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Hangzhou Think Chemical Co. Ltd

HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about ten years of business experiences on the marketing & distribution, thinkchem specializes in exporti

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Cas:312753-53-0

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

s5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride CAS NO.312753-53-0

Cas:312753-53-0

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

Type:Manufacturers

inquiry

Henan Allgreen Chemical Co.,Ltd

5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride Basic information Product Name: 5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride Synonyms: 5,6-Diethyl-

5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Cas:312753-53-0

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Cas:312753-53-0

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Cas:312753-53-0

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Cas:312753-53-0

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Jinan Finer Chemical Co., Ltd

Product Description Product website: http://www.finerchem.com/pro01en/id/1114.html Product Name 5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride CA

5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Cas:312753-53-0

Min.Order:1 Gram

FOB Price: $66.0

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

TIANFUCHEM--312753-53-0--High purity 5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride factory price Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in Chi

TIANFUCHEM--312753-53-0--High purity 5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride factory price

Cas:312753-53-0

Min.Order:1 Metric Ton

FOB Price: $2000.0

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 312753-53-0 with competitive price

Cas:312753-53-0

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by email in time prod

1H-Inden-2-amine,5,6-diethyl-2,3-dihydro-, hydrochloride (1:1)

Cas:312753-53-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride 312753-53-0

Cas:312753-53-0

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

inquiry

Hubei Langyou International Trading Co., Ltd

Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best s

Indaprol Intermediate Manufacturer CAS:312753-53-0

Cas:312753-53-0

Min.Order:10 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1H-Inden-2-amine,5,6-diethyl-2,3-dihydro-, hydrochloride (1:1) 312753-53-0

Cas:312753-53-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Cas:312753-53-0

Min.Order:1 Kilogram

FOB Price: $6000.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride CAS:312753-53-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specia

5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride CAS:312753-53-0

Cas:312753-53-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

312753-53-0/5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Cas:312753-53-0

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

1H-Inden-2-amine,5,6-diethyl-2,3-dihydro-, hydrochloride (1:1)

Cas:312753-53-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Triumph International Development Limilted

Product name: sodium metabisulfite / sodium metabisulphite Molecular weight: 190.10 Specification: 25Kg woven bag Quality guarantee period: 6 months Appearance:white powder Storage:Room Temperature Package:Carton(The aluminum foil

5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Cas:312753-53-0

Min.Order:10 Gram

FOB Price: $10.0

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

5, 6-Diethyl-2,3-dihydro-1H- inden - 2-amine hydrochloride

Cas:312753-53-0

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Cas:312753-53-0

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Cas:312753-53-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Cas:312753-53-0

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Cas:312753-53-0

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Cas:312753-53-0

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: 1H-Inden-2-Amine,5,6-Diethyl-2,3-Dihydro-,Hydrochloride CAS No.:312753-53-0 Molecule Formula:C13H20ClN Molecule Weight:225.76 Purity: 98.0% Package: 25kg/drum Description:White or off-white powder Manufacture Standards:Enterprise

High Quality 1H-Inden-2-Amine,5,6-Diethyl-2,3-Dihydro-,Hydrochloride on stock

Cas:312753-53-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

5,6-diethyl-2,3-dihydro-1H-inden-2-amine

Cas:312753-53-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Cas:312753-53-0

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

Hangzhou Huarong Pharm Co., Ltd.established since 2006 , has been actively developing specialty products for Finished Dosages, APIs, Intermediates, and Fine chemicals markets in North America, Europe, Korea, Japan, Mid-East and all over the World. Hu

5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Cas:312753-53-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

C15H21NO

C15H21NO

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
312753-53-0

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In water for 10h; Reflux;92.6%
C13H17N3

C13H17N3

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
312753-53-0

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Conditions
ConditionsYield
Stage #1: C13H17N3 With palladium 10% on activated carbon; hydrogen In methanol under 3800.26 Torr; Autoclave;
Stage #2: With hydrogenchloride In ethyl acetate
92%
5,6-diethyl-2,3-dihydro-1H-inden-2-amine
312753-70-1

5,6-diethyl-2,3-dihydro-1H-inden-2-amine

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
312753-53-0

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In diethyl ether under 760.051 Torr; Inert atmosphere;77%
With hydrogenchloride In Isopropyl acetate at 20 - 25℃; for 2.66667h;70.8 g
5,6-diethyl-3-oxime-1H-indene-1,2(3H)-dione

5,6-diethyl-3-oxime-1H-indene-1,2(3H)-dione

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
312753-53-0

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Conditions
ConditionsYield
Stage #1: 5,6-diethyl-3-oxime-1H-indene-1,2(3H)-dione With sulfuric acid; hydrogen; 5%-palladium/activated carbon In acetic acid for 5h;
Stage #2: With sodium hydroxide pH=10;
Stage #3: With hydrogenchloride In diethyl ether
N-(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)-2,2,2-trifluoroacetamide
601487-90-5

N-(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)-2,2,2-trifluoroacetamide

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
312753-53-0

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In Isopropyl acetate; water
N-(2,3-dihydro-1H-inden-2-yl)-2,2,2-trifluoroacetamide
193756-44-4

N-(2,3-dihydro-1H-inden-2-yl)-2,2,2-trifluoroacetamide

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
312753-53-0

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: aluminum (III) chloride / neat (no solvent) / 0.25 h / 0 - 5 °C
1.2: 255 / 1 h / 0 - 10 °C
2.1: hydrogen; 5%-palladium/activated carbon / ethanol; water / 25 °C / 2250.23 Torr / Inert atmosphere
3.1: aluminum (III) chloride / dichloromethane / 0.75 h / 0 °C
3.2: 1 h / 0 - 5 °C
4.1: palladium 10% on activated carbon / water; ethyl acetate / 0.17 h / 25 °C / 2828.7 Torr / Inert atmosphere
5.1: sodium hydroxide / ethanol / 1.5 h / 78 °C / Inert atmosphere
6.1: hydrogenchloride / Isopropyl acetate / 2.67 h / 20 - 25 °C
View Scheme
N-(5-acetyl-2,3-dihydro-1H-inden-2-yl)-2,2,2-trifluoroacetamide
601487-87-0

N-(5-acetyl-2,3-dihydro-1H-inden-2-yl)-2,2,2-trifluoroacetamide

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
312753-53-0

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: hydrogen; 5%-palladium/activated carbon / ethanol; water / 25 °C / 2250.23 Torr / Inert atmosphere
2.1: aluminum (III) chloride / dichloromethane / 0.75 h / 0 °C
2.2: 1 h / 0 - 5 °C
3.1: palladium 10% on activated carbon / water; ethyl acetate / 0.17 h / 25 °C / 2828.7 Torr / Inert atmosphere
4.1: sodium hydroxide / ethanol / 1.5 h / 78 °C / Inert atmosphere
5.1: hydrogenchloride / Isopropyl acetate / 2.67 h / 20 - 25 °C
View Scheme
N-(5-ethyl-2,3-dihydro-1H-inden-2-yl)-2,2,2-trifluoroacetamide
601487-88-1

N-(5-ethyl-2,3-dihydro-1H-inden-2-yl)-2,2,2-trifluoroacetamide

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
312753-53-0

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: aluminum (III) chloride / dichloromethane / 0.75 h / 0 °C
1.2: 1 h / 0 - 5 °C
2.1: palladium 10% on activated carbon / water; ethyl acetate / 0.17 h / 25 °C / 2828.7 Torr / Inert atmosphere
3.1: sodium hydroxide / ethanol / 1.5 h / 78 °C / Inert atmosphere
4.1: hydrogenchloride / Isopropyl acetate / 2.67 h / 20 - 25 °C
View Scheme
N-(5-acetyl-6-ethyl-2,3-dihydro-1H-inden-2-yl)-2,2,2-trifluoroacetamide
601487-89-2

N-(5-acetyl-6-ethyl-2,3-dihydro-1H-inden-2-yl)-2,2,2-trifluoroacetamide

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
312753-53-0

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: palladium 10% on activated carbon / water; ethyl acetate / 0.17 h / 25 °C / 2828.7 Torr / Inert atmosphere
2: sodium hydroxide / ethanol / 1.5 h / 78 °C / Inert atmosphere
3: hydrogenchloride / Isopropyl acetate / 2.67 h / 20 - 25 °C
View Scheme
2,3-dihydro-1H-inden-2-amine
2975-41-9

2,3-dihydro-1H-inden-2-amine

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
312753-53-0

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1.1: Isopropyl acetate / 3.17 h / 0 - 25 °C
2.1: aluminum (III) chloride / neat (no solvent) / 0.25 h / 0 - 5 °C
2.2: 255 / 1 h / 0 - 10 °C
3.1: hydrogen; 5%-palladium/activated carbon / ethanol; water / 25 °C / 2250.23 Torr / Inert atmosphere
4.1: aluminum (III) chloride / dichloromethane / 0.75 h / 0 °C
4.2: 1 h / 0 - 5 °C
5.1: palladium 10% on activated carbon / water; ethyl acetate / 0.17 h / 25 °C / 2828.7 Torr / Inert atmosphere
6.1: sodium hydroxide / ethanol / 1.5 h / 78 °C / Inert atmosphere
7.1: hydrogenchloride / Isopropyl acetate / 2.67 h / 20 - 25 °C
View Scheme
Multi-step reaction with 6 steps
1.1: triethylamine / dichloromethane / 2 h / 10 - 20 °C
2.1: aluminum (III) chloride / dichloromethane / 0.33 h / 0 - 10 °C
2.2: 1 h / 10 - 20 °C
3.1: 5%-palladium/activated carbon; hydrogen / ethanol / 6 h / 20 °C
4.1: aluminum (III) chloride / dichloromethane / 0.33 h / 0 - 10 °C
4.2: 1 h / 0 - 10 °C
5.1: 5%-palladium/activated carbon; hydrogen / ethanol / 6 h / 20 °C
6.1: hydrogenchloride / water / 10 h / Reflux
View Scheme
N-indan-2-yl-acetamide
13935-80-3

N-indan-2-yl-acetamide

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
312753-53-0

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: aluminum (III) chloride / dichloromethane / 0.33 h / 0 - 10 °C
1.2: 1 h / 10 - 20 °C
2.1: 5%-palladium/activated carbon; hydrogen / ethanol / 6 h / 20 °C
3.1: aluminum (III) chloride / dichloromethane / 0.33 h / 0 - 10 °C
3.2: 1 h / 0 - 10 °C
4.1: 5%-palladium/activated carbon; hydrogen / ethanol / 6 h / 20 °C
5.1: hydrogenchloride / water / 10 h / Reflux
View Scheme
N-(5-acetyl-2,3-dihydro-1H-inden-2-yl)acetamide
114149-10-9

N-(5-acetyl-2,3-dihydro-1H-inden-2-yl)acetamide

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
312753-53-0

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: 5%-palladium/activated carbon; hydrogen / ethanol / 6 h / 20 °C
2.1: aluminum (III) chloride / dichloromethane / 0.33 h / 0 - 10 °C
2.2: 1 h / 0 - 10 °C
3.1: 5%-palladium/activated carbon; hydrogen / ethanol / 6 h / 20 °C
4.1: hydrogenchloride / water / 10 h / Reflux
View Scheme
N-(5-ethyl-2,3-dihydro-1H-inden-2-yl)acetamide

N-(5-ethyl-2,3-dihydro-1H-inden-2-yl)acetamide

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
312753-53-0

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: aluminum (III) chloride / dichloromethane / 0.33 h / 0 - 10 °C
1.2: 1 h / 0 - 10 °C
2.1: 5%-palladium/activated carbon; hydrogen / ethanol / 6 h / 20 °C
3.1: hydrogenchloride / water / 10 h / Reflux
View Scheme
indan-2-ol
4254-29-9

indan-2-ol

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
312753-53-0

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 0 - 20 °C
2: bromine; N-Bromosuccinimide / acetonitrile / 20 °C / Darkness
3: tetrahydrofuran / 20 °C / Inert atmosphere
4: pyridine / dichloromethane / 20 °C
5: sodium azide / N,N-dimethyl-formamide / 20 °C
6: palladium 10% on activated carbon; hydrogen / methanol / 3800.26 Torr / Autoclave
View Scheme
2-acetoxyindane
4254-31-3

2-acetoxyindane

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
312753-53-0

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: bromine; N-Bromosuccinimide / acetonitrile / 20 °C / Darkness
2: tetrahydrofuran / 20 °C / Inert atmosphere
3: pyridine / dichloromethane / 20 °C
4: sodium azide / N,N-dimethyl-formamide / 20 °C
5: palladium 10% on activated carbon; hydrogen / methanol / 3800.26 Torr / Autoclave
View Scheme
5,6-dibromoindan-2-ol acetate
862135-55-5

5,6-dibromoindan-2-ol acetate

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
312753-53-0

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: tetrahydrofuran / 20 °C / Inert atmosphere
2: pyridine / dichloromethane / 20 °C
3: sodium azide / N,N-dimethyl-formamide / 20 °C
4: palladium 10% on activated carbon; hydrogen / methanol / 3800.26 Torr / Autoclave
View Scheme
C13H18O

C13H18O

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
312753-53-0

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: pyridine / dichloromethane / 20 °C
2: sodium azide / N,N-dimethyl-formamide / 20 °C
3: palladium 10% on activated carbon; hydrogen / methanol / 3800.26 Torr / Autoclave
View Scheme
5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
312753-53-0

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

2-tert-butoxycarbonylamino-(5,6-diethyl)indane

2-tert-butoxycarbonylamino-(5,6-diethyl)indane

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 5℃; for 4.5h;96%
(R)-8-(benzyloxy)-5-(2-bromo-1-((tert-butyldimethylsilyl)oxy)ethyl)quinolin-2(1H)-one
530084-74-3

(R)-8-(benzyloxy)-5-(2-bromo-1-((tert-butyldimethylsilyl)oxy)ethyl)quinolin-2(1H)-one

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
312753-53-0

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

(R)-5- [2-(5,6-diethylindan-2-ylamino)-1-hydroxyethyl]-8-benzyloxy-1H-quinolin-2-one hydrochloride

(R)-5- [2-(5,6-diethylindan-2-ylamino)-1-hydroxyethyl]-8-benzyloxy-1H-quinolin-2-one hydrochloride

Conditions
ConditionsYield
Stage #1: (R)-8-(benzyloxy)-5-(2-bromo-1-((tert-butyldimethylsilyl)oxy)ethyl)quinolin-2(1H)-one; 5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride With sodium hydrogencarbonate In dimethyl sulfoxide at 65 - 125℃; for 6h; Inert atmosphere; Large scale;
Stage #2: With hydrogenchloride In ethanol; water at 0 - 72℃; for 27h; Large scale;
71%
(R)-1-carboxymethyl-3-(2-hydroxy-2,2-diphenylacetoxy)-1-azoniabicyclo[2.2.2]octane trifluoroacetate

(R)-1-carboxymethyl-3-(2-hydroxy-2,2-diphenylacetoxy)-1-azoniabicyclo[2.2.2]octane trifluoroacetate

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
312753-53-0

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

(R)-1-[(5,6-diethylindan-2-ylcarbamoyl)methyl]-3-(2-hydroxy-2,2-diphenylacetoxy)-1-azoniabicyclo[2.2.2]octane trifluoroacetate

(R)-1-[(5,6-diethylindan-2-ylcarbamoyl)methyl]-3-(2-hydroxy-2,2-diphenylacetoxy)-1-azoniabicyclo[2.2.2]octane trifluoroacetate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; HATU In DMF (N,N-dimethyl-formamide) at 20℃;
5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
312753-53-0

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

N,N'-(1,1'-(6-chloro-1,3,5-triazine-2,4-diyl)bis(piperidine-4,1-diyl))bis(azanediyl)bis(iminomethylene)bis(3,5-diamino-6-chloropyrazine-2-carboxamide)
1080018-19-4

N,N'-(1,1'-(6-chloro-1,3,5-triazine-2,4-diyl)bis(piperidine-4,1-diyl))bis(azanediyl)bis(iminomethylene)bis(3,5-diamino-6-chloropyrazine-2-carboxamide)

A

N,N'-(1,1'-(6-(dimethylamino)-1,3,5-triazine-2,4-diyl)bis(piperidine-4,1-diyl))bis(azanediyl)bis(aminomethan-1-yl-1-ylidene)bis(3,5-diamino-6-chloropyrazine-2-carboxamide)
1080018-54-7

N,N'-(1,1'-(6-(dimethylamino)-1,3,5-triazine-2,4-diyl)bis(piperidine-4,1-diyl))bis(azanediyl)bis(aminomethan-1-yl-1-ylidene)bis(3,5-diamino-6-chloropyrazine-2-carboxamide)

B

N,N'-(1,1'-(6-(5,6-diethyl-2,3-dihydro-1H-inden-2-ylamino)-1,3,5-triazine-2,4-diyl)bis(piperidine-4,1-diyl))bis(azanediyl)bis(aminomethan-1-yl-1-ylidene)bis(3,5-diamino-6-chloropyrazine-2-carboxamide)
1080018-53-6

N,N'-(1,1'-(6-(5,6-diethyl-2,3-dihydro-1H-inden-2-ylamino)-1,3,5-triazine-2,4-diyl)bis(piperidine-4,1-diyl))bis(azanediyl)bis(aminomethan-1-yl-1-ylidene)bis(3,5-diamino-6-chloropyrazine-2-carboxamide)

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 60 - 70℃; for 44.5h; Microwave irradiation;
5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
312753-53-0

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

C24H28BrNO4
1585234-56-5

C24H28BrNO4

C36H44N2O4

C36H44N2O4

Conditions
ConditionsYield
With sodium carbonate In water at 100℃; for 20h;
5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
312753-53-0

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

C31H34N2O3*BrH

C31H34N2O3*BrH

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sodium hydroxide / water; methanol / 0.5 h
2: butan-1-ol / 3 h / 100 - 110 °C
3: (3aR)-1-methyl-3,3-diphenyl-tetrahydro-pyrrolo[1,2-c][1,3,2]oxazaborole / tetrahydrofuran / 0 - 3 °C / Inert atmosphere
View Scheme
5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
312753-53-0

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

indacaterol maleate

indacaterol maleate

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: sodium hydroxide / water; methanol / 0.5 h
2: butan-1-ol / 3 h / 100 - 110 °C
3: (3aR)-1-methyl-3,3-diphenyl-tetrahydro-pyrrolo[1,2-c][1,3,2]oxazaborole / tetrahydrofuran / 0 - 3 °C / Inert atmosphere
4: potassium carbonate / water; methanol / 1 h
5: acetic acid; palladium 10% on activated carbon; hydrogen / methanol / 6 h / 0 - 8 °C / 750.08 - 1500.15 Torr / Inert atmosphere
6: methanol / 0.5 h / 60 °C
View Scheme
5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
312753-53-0

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

5,6-diethyl-2,3-dihydro-1H-inden-2-amine
312753-70-1

5,6-diethyl-2,3-dihydro-1H-inden-2-amine

Conditions
ConditionsYield
With sodium hydroxide In methanol; water for 0.5h;
5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
312753-53-0

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

C31H32N2O3*BrH

C31H32N2O3*BrH

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium hydroxide / water; methanol / 0.5 h
2: butan-1-ol / 3 h / 100 - 110 °C
View Scheme
5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
312753-53-0

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

(R)-8-(benzyloxy)-5-[2-[(5,6-diethyl-2,3-dihydro-1H-indole-2-yl)amino]-1-hydroxyethyl]quinolin-2(1H)-one
435273-75-9

(R)-8-(benzyloxy)-5-[2-[(5,6-diethyl-2,3-dihydro-1H-indole-2-yl)amino]-1-hydroxyethyl]quinolin-2(1H)-one

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: sodium hydroxide / water; methanol / 0.5 h
2: butan-1-ol / 3 h / 100 - 110 °C
3: (3aR)-1-methyl-3,3-diphenyl-tetrahydro-pyrrolo[1,2-c][1,3,2]oxazaborole / tetrahydrofuran / 0 - 3 °C / Inert atmosphere
4: potassium carbonate / water; methanol / 1 h
View Scheme
5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
312753-53-0

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

indacaterol
312753-06-3

indacaterol

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: sodium hydroxide / water; methanol / 0.5 h
2: butan-1-ol / 3 h / 100 - 110 °C
3: (3aR)-1-methyl-3,3-diphenyl-tetrahydro-pyrrolo[1,2-c][1,3,2]oxazaborole / tetrahydrofuran / 0 - 3 °C / Inert atmosphere
4: potassium carbonate / water; methanol / 1 h
5: acetic acid; palladium 10% on activated carbon; hydrogen / methanol / 6 h / 0 - 8 °C / 750.08 - 1500.15 Torr / Inert atmosphere
View Scheme
5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
312753-53-0

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

(R)-5- [2-(5,6-diethylindan-2-ylamino)-1-hydroxyethyl]-8-benzyloxy-1H-quinolin-2-one hydrochloride

(R)-5- [2-(5,6-diethylindan-2-ylamino)-1-hydroxyethyl]-8-benzyloxy-1H-quinolin-2-one hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: triethylamine / dichloromethane / 4.5 h / 0 - 5 °C
2.1: potassium tert-butylate / N,N-dimethyl-formamide / 4 h / -5 - 20 °C
2.2: 2 h / 20 °C
View Scheme
5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride
312753-53-0

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

(R)-5- [2-(5,6-diethylindan-2-ylamino)-1-hydroxyethyl]-8-benzyloxy-1H-quinolin-2-one benzoic acid salt

(R)-5- [2-(5,6-diethylindan-2-ylamino)-1-hydroxyethyl]-8-benzyloxy-1H-quinolin-2-one benzoic acid salt

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: triethylamine / dichloromethane / 4.5 h / 0 - 5 °C
2.1: potassium tert-butylate / N,N-dimethyl-formamide / 4 h / -5 - 20 °C
2.2: 2 h / 20 °C
3.1: potassium carbonate / ethyl acetate / pH 9 / Cooling with ice
3.2: 2 h
View Scheme
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