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China Synchem Technology Co.,Ltd

1-Phenyloxindole CAS: 3335-98-6 Linopirdine intermediate Company Profile: Synchem is dedicated to custom synthesis and manufacturing services for small molecules. We serve the needs of customers in the pharmaceutical, agrochemical, and elect

1-Phenyloxindole

Cas:3335-98-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

1-Phenyloxindole

Cas:3335-98-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Phenyloxindol? supplier in China

Cas:3335-98-6

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Phenyloxindol

Cas:3335-98-6

Min.Order:1

Negotiable

Type:Other

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

1-Phenyl-2-oxindole

Cas:3335-98-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Good quality of 1-Phenyloxindole at competitive price from Henan Tianfu Chemical: Henan Tianfu Chemical Co.,LTD was built in 2009 with an ISO certificate in the past 5 years, we have grown up as a famous fine chemicals supplier in china and we ha

1-Phenyloxindole

Cas:3335-98-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Wholesale price CAS 3335-98-6 with best price

Cas:3335-98-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

1-Phenyloxindole Category: Pharmaceutical intermediates CAS NO.: 3335-98-6 Molecular formula: C14H11NO

1-Phenyloxindole

Cas:3335-98-6

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

1-Phenyloxindole

Cas:3335-98-6

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1-Phenyloxindole 3335-98-6

Cas:3335-98-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

1-Phenyloxindole CAS:3335-98-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermedi

1-Phenyloxindole CAS:3335-98-6

Cas:3335-98-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1-Phenyloxindole

Cas:3335-98-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Changchun Artel lmport and Export trade company

Superiority We can customize and synthesize products that other suppliers may not be able to provide. Advantage cof, mof ligand manufacturer Product Detail

low price 1-Phenyloxindole CAS:3335-98-6

Cas:3335-98-6

Min.Order:100 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

1-Phenyloxindole

Cas:3335-98-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

Appearance:White to Light beige crystalline Storage:Store with seal at regular temperature Package:As your request Application:intermediate of linopirdine dihydrochloride Transportation:Store with seal at reg

1-Phenyloxindole

Cas:3335-98-6

Min.Order:1 Kilogram

FOB Price: $0.05 / 0.1

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

Phenyloxindol

Cas:3335-98-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

1-Phenyloxindole

Cas:3335-98-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

1-Phenyloxindole/High quality/Best price

Cas:3335-98-6

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality/Best price 1-Phenyloxindole

Cas:3335-98-6

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

1-Phenyloxindole

Cas:3335-98-6

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: 1-Phenyloxindole CAS No.: 3335-98-6 Molecule Formula:C14H11NO Molecule Weight:209.24 Purity: 99.0% Package: 25kg/drum Description:White powder Manufacture Standards:Enterprise Standard TESTING ITEMS

Lower Price 1-Phenyloxindole

Cas:3335-98-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

1-Phenyloxindole Basic information Product Name: 1-Phenyloxindole Synonyms: 1,3-Dihydro-1-phenyl-2H-indol-2-one 98%;1-Phenyl-2-indolinone;2-Oxo-1-phenylindoline;1-phenyl-3H-indol-2-one;1-phenyl-2(1H,3H)-indolone;N-phenyl-indole ketone;1-phenox

1-Phenyloxindole

Cas:3335-98-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

1-Phenyloxindole/High quality/Best price

Cas:3335-98-6

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

1-Phenyloxindole

Cas:3335-98-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

1-Phenyloxindole/High quality/Best price

Cas:3335-98-6

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

N-Phenyloxindole

Cas:3335-98-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

1-Phenyloxindole

Cas:3335-98-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

1-Phenyloxindole/High quality/Best price

Cas:3335-98-6

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratoryAppearance:off-white crystal powder Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

1-phenyl-3H-indol-2-one cas no. 3335-98-6 98%

Cas:3335-98-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

1-Phenyloxindole

Cas:3335-98-6

Min.Order:0

Negotiable

Type:Other

inquiry

Synthetic route

sodium; (2-phenylamino-phenyl)-acetate

sodium; (2-phenylamino-phenyl)-acetate

1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

Conditions
ConditionsYield
With trifluoroacetic anhydride Product distribution; Further Variations:; Reagents;100%
Multi-step reaction with 4 steps
1: 98 percent / dimethylformamide / 4 h / 24 °C
2: 98 percent / Et3N; DMAP / CH2Cl2 / 3.5 h / 20 - 40 °C
3: 95 percent / hydrogen / Pd/C / methanol / 3 h / 30 °C
4: polyphosphoric acid / toluene / 11 h / 110 °C
View Scheme
2-diazo-N,N-diphenyl-acetamide
38118-74-0

2-diazo-N,N-diphenyl-acetamide

1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

Conditions
ConditionsYield
With [(S)-(2-phenyl-4-pheox)Ru(CH3CN)4]PF6 In dichloromethane at 20℃; for 0.0166667h; Inert atmosphere; regioselective reaction;99%
2-chloro-N,N-diphenylacetamide
5428-43-3

2-chloro-N,N-diphenylacetamide

1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

Conditions
ConditionsYield
With palladium diacetate; triethylamine; johnphos In toluene at 80℃; for 3h;95%
With aluminium trichloride at 180 - 190℃; for 0.166667h;81.5%
With aluminium trichloride at 180 - 190℃; for 1h;75%
1-phenyl-indole-2,3-dione
723-89-7

1-phenyl-indole-2,3-dione

1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

Conditions
ConditionsYield
With hydrazine hydrate for 0.25h; Heating;92%
Stage #1: 1-phenyl-indole-2,3-dione With potassium hydroxide; hydrazine In water; ethylene glycol at 160℃; for 1.5h;
Stage #2: With hydrogenchloride In water; ethylene glycol
90%
With hydrazine hydrate In ethanol for 6h; Wolff-Kishner reduction; Heating;58%
3-(methylthio)-1-phenylindolin-2-one
79388-20-8

3-(methylthio)-1-phenylindolin-2-one

1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

Conditions
ConditionsYield
With nickel In ethanol for 2h; Heating;85%
2-acetoxy-N,N-diphenylacetamide

2-acetoxy-N,N-diphenylacetamide

1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

Conditions
ConditionsYield
With sulfuric acid; tetrabutylammomium bromide In 5,5-dimethyl-1,3-cyclohexadiene at 100℃; for 16h; Solvent; Reagent/catalyst;84%
2-oxoindole
59-48-3

2-oxoindole

iodobenzene
591-50-4

iodobenzene

1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

Conditions
ConditionsYield
With copper(l) iodide; potassium carbonate; N,N`-dimethylethylenediamine In 1,4-dioxane for 24h; Reflux;83%
With copper(l) iodide; potassium carbonate; N,N`-dimethylethylenediamine In acetonitrile Reflux; Inert atmosphere;82%
With potassium phosphate; copper(l) iodide In dimethyl sulfoxide at 130℃; for 24h; Ullmann Condensation; Inert atmosphere; Glovebox;41 %Chromat.
With potassium phosphate; copper(l) iodide; 3-azapentane-1,5-diamine In dimethyl sulfoxide at 50℃; for 24h; Reagent/catalyst; Inert atmosphere; Glovebox; Sealed tube;27 %Chromat.
2-(2-bromophenyl)-N-phenylacetamide
120230-90-2

2-(2-bromophenyl)-N-phenylacetamide

1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

Conditions
ConditionsYield
With caesium carbonate; XPhos; palladium diacetate In toluene at 100℃; for 0.5h; microwave irradiation;82%
2-(2-chlorophenyl)-N-phenylacetamide
71512-21-5

2-(2-chlorophenyl)-N-phenylacetamide

1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

Conditions
ConditionsYield
With caesium carbonate; XPhos; palladium diacetate In toluene at 100℃; for 0.5h; microwave irradiation;80%
methyl (2-nitrophenyl)acetate
30095-98-8

methyl (2-nitrophenyl)acetate

phenylboronic acid
98-80-6

phenylboronic acid

1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

Conditions
ConditionsYield
With 1,2,2,3,4,4-hexamethylphosphetane 1-oxide; diphenylsilane In m-xylene at 120℃; for 4h; Catalytic behavior; Reagent/catalyst; Solvent; Inert atmosphere; Schlenk technique; Sealed tube;80%
diphenylamine
122-39-4

diphenylamine

chloroacetyl chloride
79-04-9

chloroacetyl chloride

1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

Conditions
ConditionsYield
With montmorillonite KSF at 20℃; for 1.08333h; Stolle synthesis; Sonication; Neat (no solvent);76%
2-bromo-N,N-diphenylacetamide
6335-34-8

2-bromo-N,N-diphenylacetamide

A

1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

B

N,N-diphenylacetamide
519-87-9

N,N-diphenylacetamide

Conditions
ConditionsYield
With tri-n-butyl-tin hydride; 2,2'-azobis(isobutyronitrile) In toluene for 14h; Heating;A 8%
B 75%
2-chloro-N,N-diphenylacetamide
5428-43-3

2-chloro-N,N-diphenylacetamide

A

1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

B

N,N-diphenylacetamide
519-87-9

N,N-diphenylacetamide

Conditions
ConditionsYield
With tri-n-butyl-tin hydride; 2,2'-azobis(isobutyronitrile) In toluene for 14h; Heating;A 11%
B 74%
2-[(methoxycarbonyl)phenylamino]benzeneacetic acid
353497-35-5

2-[(methoxycarbonyl)phenylamino]benzeneacetic acid

A

1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

B

10,11-dihydro-10-oxo-5H-dibenz[b,f]azepine-5-carboxylic acid methyl ester
353497-31-1

10,11-dihydro-10-oxo-5H-dibenz[b,f]azepine-5-carboxylic acid methyl ester

Conditions
ConditionsYield
With PPA at 95℃; for 3h;A n/a
B 70%
C18H21NO2

C18H21NO2

1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

Conditions
ConditionsYield
at 120℃; for 60h;68%
1-phenyl-1H-indole
16096-33-6

1-phenyl-1H-indole

1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

Conditions
ConditionsYield
With water; iodine In N,N-dimethyl-formamide for 12h; Reflux;62%
With 1-fluoro-1,2-phenyliodohydrin-3-(1H)-one In 1,4-dioxane; water at 140℃; for 5h;61%
With 1-fluoro-1,2-phenyliodohydrin-3-(1H)-one In 1,4-dioxane; water at 140℃; for 5h;61%
2-oxoindole
59-48-3

2-oxoindole

2-(trimethylsilyl)phenyl trifluoromethanesulfonate
88284-48-4

2-(trimethylsilyl)phenyl trifluoromethanesulfonate

A

1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

B

N-phenyl-1,3-dihydro-3,3-diphenyl-2H-indol-2-one
124145-27-3

N-phenyl-1,3-dihydro-3,3-diphenyl-2H-indol-2-one

Conditions
ConditionsYield
With cesium fluoride In acetonitrile at 20℃; for 6h;A 45%
B 26%
With cesium fluoride In acetonitrile at 75℃; for 6h; Reagent/catalyst;A 22%
B 39%
2-oxoindole
59-48-3

2-oxoindole

bromobenzene
108-86-1

bromobenzene

1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

Conditions
ConditionsYield
With potassium carbonate; N,N`-dimethylethylenediamine; copper(l) iodide In acetonitrile Heating;43%
{2-[Phenyl-(2,2,2-trifluoro-acetyl)-amino]-phenyl}-acetic acid
731851-81-3

{2-[Phenyl-(2,2,2-trifluoro-acetyl)-amino]-phenyl}-acetic acid

A

1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

B

5-trifluoroacetyl-5,11-dihydro-dibenzo[b,f]azepin-10-one
731851-85-7

5-trifluoroacetyl-5,11-dihydro-dibenzo[b,f]azepin-10-one

Conditions
ConditionsYield
With PPA In toluene at 110℃; for 11h;A n/a
B 40%
2-bromo-N,N-diphenylacetamide
6335-34-8

2-bromo-N,N-diphenylacetamide

1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

Conditions
ConditionsYield
Multistep reaction.;39%
In acetonitrile Cyclization; Dehydrobromination; Irradiation;26%
Multistep reaction;24 mg
Multi-step reaction with 2 steps
1: N,N'-ditosylhydrazine; 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere
2: [(S)-(2-phenyl-4-pheox)Ru(CH3CN)4]PF6 / dichloromethane / 0.02 h / 20 °C / Inert atmosphere
View Scheme
2-oxoindole
59-48-3

2-oxoindole

2-(trimethylsilyl)phenyl trifluoromethanesulfonate
88284-48-4

2-(trimethylsilyl)phenyl trifluoromethanesulfonate

A

1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

B

5,11-diphenyl-5H-dibenzo[b,e]azepin-6(11H)-one

5,11-diphenyl-5H-dibenzo[b,e]azepin-6(11H)-one

C

N-phenyl-1,3-dihydro-3,3-diphenyl-2H-indol-2-one
124145-27-3

N-phenyl-1,3-dihydro-3,3-diphenyl-2H-indol-2-one

Conditions
ConditionsYield
With cesium fluoride In acetonitrile at 20℃; for 6h;A 15%
B 8%
C 32%
3-hydroxy-1-phenyl-1,4,5,6-tetrahydro-indol-2-one
52480-52-1

3-hydroxy-1-phenyl-1,4,5,6-tetrahydro-indol-2-one

1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

Conditions
ConditionsYield
With pyridine hydrochloride at 230℃; for 1h;12.4%
With pyridine hydrochloride at 230℃; for 1h; Product distribution; other time, temperature;12.4%
2-chloro-N,N-diphenylacetamide
5428-43-3

2-chloro-N,N-diphenylacetamide

A

1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

B

3-hydroxy-1,1'-diphenyl-1,3,1',3'-tetrahydro-[3,3']biindolyl-2,2'-dione

3-hydroxy-1,1'-diphenyl-1,3,1',3'-tetrahydro-[3,3']biindolyl-2,2'-dione

Conditions
ConditionsYield
With aluminium trichloride
1-phenyl-3.3-dichloro-oxindole

1-phenyl-3.3-dichloro-oxindole

1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

Conditions
ConditionsYield
With calcium hypochlorite; water
2-[2-(phenylamino)phenyl]acetic acid
70172-33-7

2-[2-(phenylamino)phenyl]acetic acid

1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

Conditions
ConditionsYield
With PPA In toluene at 110℃; for 11h; Product distribution; Further Variations:; Reagents; Solvents; Temperatures;
[2-(acetyl-phenyl-amino)-phenyl]-acetic acid
731851-88-0

[2-(acetyl-phenyl-amino)-phenyl]-acetic acid

A

1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

B

5-acetyl-1,3-dihydro-1-phenyl-2H-indol-2-one

5-acetyl-1,3-dihydro-1-phenyl-2H-indol-2-one

Conditions
ConditionsYield
With PPA at 95℃; for 3h; Product distribution;A n/a
B 35 % Chromat.
[2-(benzyl-phenyl-amino)-phenyl]-acetic acid
731851-78-8

[2-(benzyl-phenyl-amino)-phenyl]-acetic acid

1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

Conditions
ConditionsYield
With PPA In chlorobenzene at 90℃; for 2h; Product distribution;
diphenylamine
122-39-4

diphenylamine

1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 42 percent / NEt3 / CH2Cl2 / 16 h / 20 °C
View Scheme
Multi-step reaction with 3 steps
1: 98 percent / 2 h / 20 °C
2: 83 percent / AlCl3 / CS2 / 2 h / 20 °C
3: 58 percent / hydrazine hydrate / ethanol / 6 h / Heating
View Scheme
Multi-step reaction with 2 steps
1: 97 percent / dimethylformamide / 2 h / 80 °C
2: 75 percent / AlCl3 / 1 h / 180 - 190 °C
View Scheme
(N,N-diphenylcarbamoyl) formyl chloride
75385-92-1

(N,N-diphenylcarbamoyl) formyl chloride

1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 83 percent / AlCl3 / CS2 / 2 h / 20 °C
2: 58 percent / hydrazine hydrate / ethanol / 6 h / Heating
View Scheme
1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

sodium; (2-phenylamino-phenyl)-acetate

sodium; (2-phenylamino-phenyl)-acetate

Conditions
ConditionsYield
With sodium hydroxide at 100℃; for 6h;97%
1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

4-tert-butylphenyltosylate
7598-28-9

4-tert-butylphenyltosylate

3-(4-tert-butylphenyl)-1-phenylindolin-2-one

3-(4-tert-butylphenyl)-1-phenylindolin-2-one

Conditions
ConditionsYield
With potassium fluoride; 2-[2-(dicyclohexylphosphino)-phenyl]-1-methyl-1H-indole; palladium diacetate In tert-butyl alcohol at 20 - 120℃; for 18.0833h; Inert atmosphere; Schlenk technique;97%
1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

para-thiocresol
106-45-6

para-thiocresol

1-phenyl-3-(p-tolylthio)indolin-2-one

1-phenyl-3-(p-tolylthio)indolin-2-one

Conditions
ConditionsYield
With oxygen; sodium hydroxide In N,N-dimethyl-formamide at 0℃; for 6h; Green chemistry;97%
1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

trifluoromethylsulfonic anhydride
358-23-6

trifluoromethylsulfonic anhydride

1-phenyl-1H-indol-2-yl trifluoromethanesulfonate
1373936-46-9

1-phenyl-1H-indol-2-yl trifluoromethanesulfonate

Conditions
ConditionsYield
With 2,4,6-tri-tertbutylpyridine In 1,2-dichloro-ethane at 0 - 20℃; Inert atmosphere;96%
1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

ethyl 2,3-butadienoate
14369-81-4

ethyl 2,3-butadienoate

C26H27NO5

C26H27NO5

Conditions
ConditionsYield
With triphenylphosphine In 5,5-dimethyl-1,3-cyclohexadiene at 50℃; for 24h; Inert atmosphere;96%
1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

(SS)-2-methyl-N-(2,2,2-trifluoroethylidene)-propane-2-sulfinamide

(SS)-2-methyl-N-(2,2,2-trifluoroethylidene)-propane-2-sulfinamide

A

(S)-2-methyl-N-(2,2,2-trifluoro-1-(2-oxo-1-phenylindolin-3-yl)ethyl)propane-2-sulfinamide

(S)-2-methyl-N-(2,2,2-trifluoro-1-(2-oxo-1-phenylindolin-3-yl)ethyl)propane-2-sulfinamide

B

(S)-2-methyl-N-((S)-2,2,2-trifluoro-1-((S)-2-oxo-1-phenylindolin-3-yl)ethyl)propane-2-sulfinamide

(S)-2-methyl-N-((S)-2,2,2-trifluoro-1-((S)-2-oxo-1-phenylindolin-3-yl)ethyl)propane-2-sulfinamide

Conditions
ConditionsYield
Stage #1: 1-phenyl-1,3-dihydro-indol-2-one With lithium diisopropyl amide In hexane; dichloromethane at -78℃; for 1h; Inert atmosphere;
Stage #2: (SS)-2-methyl-N-(2,2,2-trifluoroethylidene)-propane-2-sulfinamide In hexane; dichloromethane at -78℃; for 5h; Inert atmosphere;
Stage #3: With ammonium chloride In hexane; dichloromethane; water at -78℃; Inert atmosphere; diastereoselective reaction;
A n/a
B 95%
1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

chlorobenzene
108-90-7

chlorobenzene

1,3-dihydro-1,3-diphenyl-2H-indol-2-one
23210-25-5

1,3-dihydro-1,3-diphenyl-2H-indol-2-one

Conditions
ConditionsYield
With copper(II) ferrite; potassium carbonate In 1,4-dioxane at 70℃; for 1.33333h; Reagent/catalyst;95%
1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

chlorobenzene
108-90-7

chlorobenzene

A

1,3-dihydro-1,3-diphenyl-2H-indol-2-one
23210-25-5

1,3-dihydro-1,3-diphenyl-2H-indol-2-one

B

N-phenyl-1,3-dihydro-3,3-diphenyl-2H-indol-2-one
124145-27-3

N-phenyl-1,3-dihydro-3,3-diphenyl-2H-indol-2-one

Conditions
ConditionsYield
With cobalt ferrite; potassium carbonate In 1,4-dioxane at 70℃; for 4h;A 95%
B 8%
1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

malononitrile
109-77-3

malononitrile

2-(2-oxo-1-phenylindolin-3-ylidene)malononitrile
1370462-98-8

2-(2-oxo-1-phenylindolin-3-ylidene)malononitrile

Conditions
ConditionsYield
With iron(III) chloride hexahydrate; oxygen In N,N-dimethyl-formamide at 50℃; for 2h; Green chemistry;95%
1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

octanol
111-87-5

octanol

C22H27NO
1571113-82-0

C22H27NO

Conditions
ConditionsYield
In 1,3,5-trimethyl-benzene at 170℃; for 24h; Inert atmosphere;94%
1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

5-chloroindole 2,3-dione
17630-76-1

5-chloroindole 2,3-dione

(E)-5'-chloro-1-phenyl-[3,3'-biindolinylidene]-2,2'-dione

(E)-5'-chloro-1-phenyl-[3,3'-biindolinylidene]-2,2'-dione

Conditions
ConditionsYield
With zirconium(IV) chloride In ethanol for 10h; Reflux;94%
1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

formic acid ethyl ester
109-94-4

formic acid ethyl ester

3-(Hydroxymethylene)-1-phenyloxindole

3-(Hydroxymethylene)-1-phenyloxindole

Conditions
ConditionsYield
With potassium tert-butylate In ethanol at 80℃; for 0.0833333h;93%
In ethanol
1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

4-bromobenzenecarbonitrile
623-00-7

4-bromobenzenecarbonitrile

C21H14N2O

C21H14N2O

Conditions
ConditionsYield
With nickel(II) ferrite; potassium carbonate In 1,4-dioxane at 70℃; for 1.66667h; Reagent/catalyst;93%
ammonium thiocyanate

ammonium thiocyanate

1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

1-phenyl-5-thiocyanato-1,3-dihydro-indol-2-one

1-phenyl-5-thiocyanato-1,3-dihydro-indol-2-one

Conditions
ConditionsYield
With iodine In methanol at 20℃; for 0.416667h;92%
1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

benzyl alcohol
100-51-6

benzyl alcohol

3-benzyl-1,3-dihydro-1-phenyl-2H-indol-2-one
23226-10-0

3-benzyl-1,3-dihydro-1-phenyl-2H-indol-2-one

Conditions
ConditionsYield
In 1,3,5-trimethyl-benzene at 170℃; for 24h; Inert atmosphere;92%
With (1,4-dimethyl-5,7-diphenyl-1,2,3,4-tetrahydro-6H-cyclopenta[b]pyrazin-6-one) irontricarbonyl complex3; potassium carbonate; triphenylphosphine In 5,5-dimethyl-1,3-cyclohexadiene at 150℃; for 24h;75%
1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

p-Chlorothiophenol
106-54-7

p-Chlorothiophenol

3-((4-chlorophenyl)thio)-1-phenylindolin-2-one

3-((4-chlorophenyl)thio)-1-phenylindolin-2-one

Conditions
ConditionsYield
With iron(III) chloride; potassium carbonate In dimethyl sulfoxide at 50℃; for 1h; Green chemistry;92%
1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

indole-2,3-dione
91-56-5

indole-2,3-dione

(E)-1-phenyl-[3,3'-biindolinylidene]-2,2'-dione

(E)-1-phenyl-[3,3'-biindolinylidene]-2,2'-dione

Conditions
ConditionsYield
With zirconium(IV) chloride In ethanol Reflux;91%
With zirconium(IV) chloride In ethanol for 9h; Reflux;91%
With hydrogenchloride; acetic acid
1-bromo-4-methoxy-benzene
104-92-7

1-bromo-4-methoxy-benzene

1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

C21H17NO2

C21H17NO2

Conditions
ConditionsYield
With copper(II) ferrite; potassium carbonate In 1,4-dioxane at 70℃; for 2h; Reagent/catalyst;91%
1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

para-chloroacetophenone
99-91-2

para-chloroacetophenone

C22H17NO2

C22H17NO2

Conditions
ConditionsYield
With nickel(II) ferrite; potassium carbonate In 1,4-dioxane at 70℃; for 1.66667h; Reagent/catalyst;91%
1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

1-isopropyl-1H-indole-2,3-dione
10487-31-7

1-isopropyl-1H-indole-2,3-dione

(E)-1-isopropyl-1'-phenyl-[3,3'-biindolinylidene]-2,2'-dione

(E)-1-isopropyl-1'-phenyl-[3,3'-biindolinylidene]-2,2'-dione

Conditions
ConditionsYield
With zirconium(IV) chloride In ethanol Reflux;91%
1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

anthranilic acid amide
28144-70-9

anthranilic acid amide

1-phenyl-1'H-spiro[indoline-3,2'-quinazoline]-2,4'(3'H)-dione
1420904-39-7

1-phenyl-1'H-spiro[indoline-3,2'-quinazoline]-2,4'(3'H)-dione

Conditions
ConditionsYield
With iron(III) chloride; toluene-4-sulfonic acid In N,N-dimethyl-formamide at 80℃; for 3.5h;91%
1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

2-aminobenzanilide
4424-17-3

2-aminobenzanilide

1,3'-diphenyl-1'H-spiro[indoline-3,2'-quinazoline]-2,4'(3'H)-dione

1,3'-diphenyl-1'H-spiro[indoline-3,2'-quinazoline]-2,4'(3'H)-dione

Conditions
ConditionsYield
With iron(III) chloride; toluene-4-sulfonic acid In N,N-dimethyl-formamide at 80℃; for 1h;91%
1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

2-[2-(phenylamino)phenyl]acetic acid
70172-33-7

2-[2-(phenylamino)phenyl]acetic acid

Conditions
ConditionsYield
With sodium hydroxide In ethanol for 4h; Heating;90%
With sodium hydroxide In ethanol for 4h; Heating;88%
With sodium hydroxide In ethanol; water for 4h; Heating; Yield given;
Multi-step reaction with 2 steps
1: 97 percent / aq. NaOH / 6 h / 100 °C
2: acid / pH 2
View Scheme
1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

4-picolylchloride hydrochloride
1822-51-1

4-picolylchloride hydrochloride

linopirdine
105431-72-9

linopirdine

Conditions
ConditionsYield
With potassium fluoride on basic alumina for 0.05h; microwave irradiation;90%
1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

1-phenyl-indole-2,3-dione
723-89-7

1-phenyl-indole-2,3-dione

Conditions
ConditionsYield
With oxygen; sodium iodide In tetrahydrofuran at 60℃; for 12h; Schlenk technique; chemoselective reaction;90%
With tert.-butylhydroperoxide In 1,2-dichloro-ethane at 85℃; for 24h; Schlenk technique;84%
With tert.-butylnitrite; oxygen In tetrahydrofuran at 50℃; under 760.051 Torr; for 24h; Schlenk technique; Inert atmosphere;80%
With tert.-butylnitrite In tetrahydrofuran at 25℃; under 1520.1 Torr;66%
1-phenyl-1,3-dihydro-indol-2-one
3335-98-6

1-phenyl-1,3-dihydro-indol-2-one

N-butylisatin
4290-91-9

N-butylisatin

(E)-1-butyl-1'-phenyl-[3,3'-biindolylidene]-2,2'-dione

(E)-1-butyl-1'-phenyl-[3,3'-biindolylidene]-2,2'-dione

Conditions
ConditionsYield
With zirconium(IV) chloride In ethanol for 10h; Reflux;90%

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