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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

Thiochroman-4-one

Cas:3528-17-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Manufacturer supply CAS 3528-17-4 with best quality

Cas:3528-17-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

Thiochroman-4-one

Cas:3528-17-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Thiochroman-4-one

Cas:3528-17-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:3528-17-4

Cas:3528-17-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Thiochroman-4-one CAS NO.3528-17-4

Cas:3528-17-4

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Thiochroman-4-one

Cas:3528-17-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

Thiochroman-4-one CAS NO.3528-17-4

Cas:3528-17-4

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

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Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

Thiochroman-4-one

Cas:3528-17-4

Min.Order:0

Negotiable

Type:Trading Company

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Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

Thiochroman-4-one CAS NO.3528-17-4

Cas:3528-17-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

Thiochroman-4-one CAS NO.3528-17-4

Cas:3528-17-4

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

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Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

3528-17-4

Cas:3528-17-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

Thiochroman-4-one CAS NO.3528-17-4

Cas:3528-17-4

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

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GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

thiochroman-4-one

Cas:3528-17-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

thiochroman-4-one

Cas:3528-17-4

Min.Order:0

Negotiable

Type:Other

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Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec Thiochroman-4-one 5g

Cas:3528-17-4

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Thiochroman-4-one, 98%

Cas:3528-17-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

Thiochroman-4-one Application:Organic Chemicals

3528-17-4

Cas:3528-17-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

We are a trading company aiming at providing high-quality services to customers. Established for many years, with good reputation in the industry Storage:Sealed and preserved Application:Fine chemical intermediates, used as the main raw material for

Thiochroman-4-one CAS NO.3528-17-4

Cas:3528-17-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hubei Langyou International Trading Co., Ltd

Thiochroman-4-one CAS NO.3528-17-4 Application:Thiochroman-4-one CAS NO.3528-17-4

Thiochroman-4-one CAS NO.3528-17-4

Cas:3528-17-4

Min.Order:0

Negotiable

Type:Other

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Changchun Artel lmport and Export trade company

Supply top quality products with a reasonable price Application:api

3528-17-4

Cas:3528-17-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

Thiochroman-4-one cas 3528-17-4Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

Thiochroman-4-one cas 3528-17-4

Cas:3528-17-4

Min.Order:0

Negotiable

Type:Other

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Hangzhou Sartort Biopharma Co., Ltd

Best quality with low price Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Shanghai

thiochroman-4-one

Cas:3528-17-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

Thiochroman-4-one

Cas:3528-17-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hunan Longxianng Runhui Trading Co.,Ltd

Thiochroman-4-one CAS NO.3528-17-4Appearance:off-white fine crystalline powder Storage:Dry and ventilated Package:Standard or as customer's require Application:intermediates Transportation:By express (Door to door) such as FEDEX, DHL, EMS for small a

Thiochroman-4-one CAS NO.3528-17-4

Cas:3528-17-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Saiwante (shanghai) New Material Technology Co., Ltd.

Stable supply of goods and provision of high-quality services Application:As raw materials in the field of medicine and biology

Thiochroman-4-one CAS NO.3528-17-4

Cas:3528-17-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Application:Medical or chemical

3528-17-4

Cas:3528-17-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Chemsigma International Co.,Ltd.

bulk?production Application:Pharmaceutical intermediates

THIOCHROMAN-4-ONE

Cas:3528-17-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

Thiochroman-4-one

Cas:3528-17-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

LEAP CHEM Co., Ltd.

Best Seller, High Quality, Competitive Price, Fast Delivery, Quick ResponseAppearance:powder, or liquid Storage:Stored in room temperature, ventilated place Package:Bottle, barrel, cargo, container, etc. Application:Pharmaceuticals, intermediates, AP

硫代色满-4-酮

Cas:3528-17-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

thiochroman-4-ol
40316-60-7

thiochroman-4-ol

2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

Conditions
ConditionsYield
With dimethyl sulfoxide; triethylamine In dichloromethane at -40 - 20℃; for 8h;93%
With 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione In dimethyl sulfoxide for 24h; Ambient temperature;92%
With ammonium nitrate; hydrogenchloride; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; oxygen In water; acetonitrile at 60℃; for 18h; Green chemistry;85%
thiochroman-4-one semicarbazone
93622-03-8

thiochroman-4-one semicarbazone

2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

Conditions
ConditionsYield
With potassium permanganate; silica gel In water at 20℃; for 0.416667h;91%
acide phenylthio-3 propanoique
5219-65-8

acide phenylthio-3 propanoique

2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

Conditions
ConditionsYield
With PPA for 0.0166667h; microwave irradiation;80%
With sulfuric acid at 110℃; for 4h;80%
With PPA at 60℃; for 96h;66%
4-(trimethylsilyloxy)thiochrom-3-ene
55454-08-5

4-(trimethylsilyloxy)thiochrom-3-ene

cyclohexanone
108-94-1

cyclohexanone

A

2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

B

3-cyclohexylidene-4-thiochromanone
94445-51-9

3-cyclohexylidene-4-thiochromanone

Conditions
ConditionsYield
With titanium tetrachloride In dichloromethane 1.) -78 deg C; 2.) 25 deg C, 18 h;A 63%
B 32%
4-(trimethylsilyloxy)thiochrom-3-ene
55454-08-5

4-(trimethylsilyloxy)thiochrom-3-ene

cyclopentanone
120-92-3

cyclopentanone

A

2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

B

thiochromen-4-one
491-39-4

thiochromen-4-one

C

3-cyclopentylidene-4-thiochromanone
94445-49-5

3-cyclopentylidene-4-thiochromanone

Conditions
ConditionsYield
With titanium tetrachloride In dichloromethane 1.) -78 deg C; 2.) 25 deg C, 18 h;A 24%
B 20%
C 22%
sulfuric acid
7664-93-9

sulfuric acid

acide phenylthio-3 propanoique
5219-65-8

acide phenylthio-3 propanoique

2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

sodium thiophenolate
930-69-8

sodium thiophenolate

cyclooctatetraene 1,2-trans-dihalide

cyclooctatetraene 1,2-trans-dihalide

2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 86 percent / 0.06 h / microwave irradiation
2: 80 percent / polyphosphoric acid / 0.02 h / microwave irradiation
View Scheme
diphenyldisulfane
882-33-7

diphenyldisulfane

1-(4-(biphenyl-4-yl)thiazol-2-yl)piperazine bound to Wang resin

1-(4-(biphenyl-4-yl)thiazol-2-yl)piperazine bound to Wang resin

2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: ethanol / Heating
2: various solvent(s) / 1 h / 100 °C / Heating
View Scheme
thiophenol
108-98-5

thiophenol

2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: NaOH-solution
2: concentrated sulfuric acid / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: NaOH-solution
2: concentrated sulfuric acid / 60 °C
View Scheme
Multi-step reaction with 2 steps
1: ethanol; water / 2 h / Reflux
2: sulfuric acid / 0 - 20 °C
View Scheme
chloropropionic acid
107-94-8

chloropropionic acid

thiophenol
108-98-5

thiophenol

2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

Conditions
ConditionsYield
With sodium hydroxide
ethyl 3-(phenylthio)propionate
60805-64-3

ethyl 3-(phenylthio)propionate

2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium hydroxide / methanol; water / Reflux
2: polyphosphoric acid / 100 °C
View Scheme
2-(phenylthio)acetaldehyde
66303-55-7

2-(phenylthio)acetaldehyde

2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: zinc; iodine / diethyl ether; benzene / 20 °C / Inert atmosphere
1.2: 24 h / Inert atmosphere
2.1: sodium hydroxide / methanol; water / Reflux
3.1: polyphosphoric acid / 100 °C
View Scheme
(phenylthio)acetic acid
103-04-8

(phenylthio)acetic acid

2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: polyphosphoric acid / 100 °C
2.1: zinc; iodine / diethyl ether; benzene / 20 °C / Inert atmosphere
2.2: 24 h / Inert atmosphere
3.1: sodium hydroxide / methanol; water / Reflux
4.1: polyphosphoric acid / 100 °C
View Scheme
2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

4-methyl-benzaldehyde
104-87-0

4-methyl-benzaldehyde

(Z)-3-(4-methylbenzylidene)thiochroman-4-one
69964-53-0, 135521-92-5, 101001-08-5

(Z)-3-(4-methylbenzylidene)thiochroman-4-one

Conditions
ConditionsYield
With hydrogenchloride In methanol for 3h;100%
With sulfuric acid In acetic acid at 20℃; for 0.333333h;89%
With hydrogenchloride In ethanol for 0.0833333h; Ambient temperature;64.1%
With piperidine In chloroform for 5h; Reflux;
With sodium hydroxide In ethanol; water at 0℃; for 0.5h;
2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

benzaldehyde
100-52-7

benzaldehyde

Z-3-benzylidene-1-thiochromanone
74074-09-2

Z-3-benzylidene-1-thiochromanone

Conditions
ConditionsYield
With hydrogenchloride In methanol for 3h;100%
With hydrogenchloride In ethanol79.6%
With piperidine In chloroform for 5h; Reflux;
With sodium hydroxide In ethanol; water at 0℃; for 0.5h;
2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

oxalic acid diethyl ester
95-92-1

oxalic acid diethyl ester

3-ethoxalyl-2,3-dihydro-1-benzothiopyran-4-one
56876-58-5

3-ethoxalyl-2,3-dihydro-1-benzothiopyran-4-one

Conditions
ConditionsYield
With sodium ethanolate In ethanol at 40℃; for 2h;100%
With sodium In ethanol Claisen Condensation;
2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

1-thiochroman-4-one 1-oxide
26524-91-4

1-thiochroman-4-one 1-oxide

Conditions
ConditionsYield
With water; silica gel; magnesium monoperoxyphthalate hexahydrate In dichloromethane at 40℃; for 1h;100%
With phthaloyl peroxide In dichloromethane at 25℃; for 8h; Schlenk technique; chemoselective reaction;99%
With sodium bromate; ammonium cerium(IV) nitrate; silica gel In dichloromethane at 20℃; for 0.566667h;96%
2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

perfluoropropionic acid methyl ester
378-75-6

perfluoropropionic acid methyl ester

lithium 3-(pentafluoropropanoyl)thiochromanonate

lithium 3-(pentafluoropropanoyl)thiochromanonate

Conditions
ConditionsYield
With methanol; lithium hydride In benzene Reflux; Inert atmosphere;100%
2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

(R)-3,4-dihydro-2H-thiochromen-4-ol
40316-60-7, 135711-13-6, 135818-63-2, 120466-74-2

(R)-3,4-dihydro-2H-thiochromen-4-ol

Conditions
ConditionsYield
With bis(1,5-cyclooctadiene)diiridium(I) dichloride; C49H64FeNOP; hydrogen; sodium t-butanolate In isopropyl alcohol at 25 - 30℃; under 38002.6 Torr; for 12h; Autoclave; enantioselective reaction;99%
With (S)-2-[(1,3,2-dioxaborolan-2-yloxy)diphenylmethyl]pyrrolidine; dimethylsulfide borane complex In tetrahydrofuran at 25℃; for 2h; Inert atmosphere; optical yield given as %ee; enantioselective reaction;92%
With [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; sodium formate In water at 30℃; for 24h; Inert atmosphere; Schlenk technique; enantioselective reaction;79%
2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

1,1-dioxo-1-thiochroman-4-one
19446-96-9

1,1-dioxo-1-thiochroman-4-one

Conditions
ConditionsYield
With dihydrogen peroxide In acetonitrile at 40℃; for 0.333333h;99%
With 3,3-dimethyldioxirane In dichloromethane; acetone at 0 - 5℃;96%
With silica gel; magnesium monoperoxyphthalate hexahydrate In dichloromethane for 1.41667h; Heating;84%
2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

(S)-3,4-dihydro-2H-thiochromen-4-ol
40316-60-7, 120466-74-2, 135818-63-2, 135711-13-6

(S)-3,4-dihydro-2H-thiochromen-4-ol

Conditions
ConditionsYield
With formic acid; [RuCl2(hexamethylbenzene)]2; (S)-2-piperidinemethanethiol hydrochloride; triethylamine at 30℃; for 24h; Inert atmosphere; optical yield given as %ee; enantioselective reaction;99%
With Cp*Ir(OTf)(Msdpen); hydrogen In methanol at 60℃; under 11400.8 Torr; for 24h; optical yield given as %ee; enantioselective reaction;99%
With formic acid; [RuCl2(hexamethylbenzene)]2; (S)-2-piperidinemethanethiol hydrochloride; triethylamine at 30℃; for 24h; Inert atmosphere; optical yield given as %ee; enantioselective reaction;99%
2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

ethane-1,2-dithiol
540-63-6

ethane-1,2-dithiol

spiro[thiochromane-4,2’-[1,3]dithiolane]

spiro[thiochromane-4,2’-[1,3]dithiolane]

Conditions
ConditionsYield
With boron trifluoride diethyl etherate In dichloromethane at 20℃; Inert atmosphere;99%
2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

thiochromane
2054-35-5

thiochromane

Conditions
ConditionsYield
With hydrogenchloride; mercury dichloride; zinc In toluene for 72h; Heating;98%
With hydrogenchloride; amalgamated zinc In toluene for 72h; Heating;98%
With molybdenum trisulfide; hydrogen In octane at 240℃; under 75006 Torr; for 1.5h;95%
2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

thiochroman-4-ol
40316-60-7

thiochroman-4-ol

Conditions
ConditionsYield
With sodium tetrahydroborate In ethanol at 20℃; Inert atmosphere;98%
With methanol; sodium tetrahydroborate at 0 - 20℃; for 0.666667h; Inert atmosphere;84%
With potassium hydroxide; Cr(L-Ala)2 In water; N,N-dimethyl-formamide for 18h; Ambient temperature; pH=9.9;74%
2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

potassium cyanide
151-50-8

potassium cyanide

ammonium carbonate
506-87-6

ammonium carbonate

spiro(hydantoin-5,4'-thiochromane)
66892-42-0

spiro(hydantoin-5,4'-thiochromane)

Conditions
ConditionsYield
In ethanol; water at 55 - 60℃; Bucherer-Bergs reaction;98%
chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

4-(trimethylsilyloxy)thiochrom-3-ene
55454-08-5

4-(trimethylsilyloxy)thiochrom-3-ene

Conditions
ConditionsYield
With triethylamine; potassium iodide In chloroform 1.) chloroform, 0 deg C; 2.) reflux, 16 h;97%
With triethylamine; potassium iodide In chloroform for 16h; Heating;94%
2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

phenylhydrazine
100-63-0

phenylhydrazine

6,11-Dihydro-5-thia-11-aza-benzo[a]fluorene
4079-26-9

6,11-Dihydro-5-thia-11-aza-benzo[a]fluorene

Conditions
ConditionsYield
With chloro-trimethyl-silane In ethanol for 4h; Reflux;96%
With chloro-trimethyl-silane In ethanol for 4h; Reflux;72%
(i) AcOH, (ii) HCl; Multistep reaction;
With hydrogenchloride In 1,4-dioxane; ethanol for 4h; Fischer indole reaction; Heating;
2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

ethyl trifluoroacetate,
383-63-1

ethyl trifluoroacetate,

3-trifluoroacetyl-thiochroman-4-one

3-trifluoroacetyl-thiochroman-4-one

Conditions
ConditionsYield
Stage #1: ethyl trifluoroacetate, With sodium hydride In tetrahydrofuran at 20℃; for 0.5h;
Stage #2: 2,3-dihydro-4H-[1]benzothiopyran-4-one In tetrahydrofuran for 2h; Reflux;
96%
With sodium methylate In methanol; diethyl ether for 16h;
2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

4-oxo-3,4-dihydro-2H-thiochromen-3-yl acetate
55444-15-0

4-oxo-3,4-dihydro-2H-thiochromen-3-yl acetate

Conditions
ConditionsYield
With acetic acid In benzene for 5h; Heating;96%
In benzene Heating;89%
2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

thiochroman-4-one oxime
15857-68-8

thiochroman-4-one oxime

Conditions
ConditionsYield
With pyridine; hydroxylamine hydrochloride at 20℃; for 1.5h;96%
With hydroxylamine hydrochloride; sodium acetate In methanol at 20℃; for 12h;90%
With pyridine; hydroxylamine hydrochloride at 20℃; for 3h;87%
2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

benzaldehyde
100-52-7

benzaldehyde

toluene-4-sulfonamide
70-55-3

toluene-4-sulfonamide

rac-(R)-3-[(S)-phenyl(tosylamino)methyl]thiochroman-4-one

rac-(R)-3-[(S)-phenyl(tosylamino)methyl]thiochroman-4-one

Conditions
ConditionsYield
With N,N,N',N'-tetramethylguanidine In toluene at 20℃; for 5h; Mannich reaction; Molecular sieve; optical yield given as %de; diastereoselective reaction;96%
2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

formic acid ethyl ester
109-94-4

formic acid ethyl ester

3-(hydroxymethylene)thiochroman-4-one
55390-63-1

3-(hydroxymethylene)thiochroman-4-one

Conditions
ConditionsYield
With sodium hydride In toluene95%
With sodium methylate In pyridine for 18h; Ambient temperature;
2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

pentafluorophenyl hydrazine
828-73-9

pentafluorophenyl hydrazine

N-pentafluorophenyl-N'-thiochroman-4-ylidene-hydrazine

N-pentafluorophenyl-N'-thiochroman-4-ylidene-hydrazine

Conditions
ConditionsYield
With acetic acid In ethanol for 3h; Condensation; Heating;95%
2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

A

1-thiochroman-4-one 1-oxide
26524-91-4

1-thiochroman-4-one 1-oxide

B

1,1-dioxo-1-thiochroman-4-one
19446-96-9

1,1-dioxo-1-thiochroman-4-one

Conditions
ConditionsYield
With 3,3-dimethyldioxirane In dichloromethane; acetone at 0 - 5℃;A 93%
B 4.8%
With dihydrogen peroxide; titanium(IV) isopropylate; L-Tartaric acid; silica gel In methanol; water at 25℃; for 24h; Title compound not separated from byproducts;A 92 % Spectr.
B 3%
With sodium periodate Yield given. Yields of byproduct given;
2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

(2,4,6-trichlorophenyl)hydrazine
5329-12-4

(2,4,6-trichlorophenyl)hydrazine

N-thiochroman-4-ylidene-N'-(2,4,6-trichloro-phenyl)-hydrazine

N-thiochroman-4-ylidene-N'-(2,4,6-trichloro-phenyl)-hydrazine

Conditions
ConditionsYield
With acetic acid In ethanol for 3h; Condensation; Heating;93%
2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

benzaldehyde
100-52-7

benzaldehyde

thiourea
17356-08-0

thiourea

4-phenyl-(5H)-(1-benzthiopyrano)-(4,3-d)-1,2,3,4-tetrahydropyrimidine-2-thione
116924-21-1

4-phenyl-(5H)-(1-benzthiopyrano)-(4,3-d)-1,2,3,4-tetrahydropyrimidine-2-thione

Conditions
ConditionsYield
With 1-butyl-3-methylimidazolium hydrogen sulfate at 70℃; for 1h; Reagent/catalyst; Temperature; Green chemistry;92%
With hydrogenchloride In butan-1-ol Heating;53.23%
2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

ethylhydrazine carboxylate
4114-31-2

ethylhydrazine carboxylate

thiochroman-4-one ethoxy carbonylhydrazone
464201-58-9

thiochroman-4-one ethoxy carbonylhydrazone

Conditions
ConditionsYield
With acetic acid In ethanol for 3h; Heating;92%
2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

benzaldehyde
100-52-7

benzaldehyde

thiourea
17356-08-0

thiourea

4-chlorobenzoylmethyl bromide
536-38-9

4-chlorobenzoylmethyl bromide

9-(4-chlorophenyl)-7-phenyl-6,7-dihydrothiazolo[3,2-a]thiochromeno[4,3 d] pyrimidine

9-(4-chlorophenyl)-7-phenyl-6,7-dihydrothiazolo[3,2-a]thiochromeno[4,3 d] pyrimidine

Conditions
ConditionsYield
Stage #1: 2,3-dihydro-4H-[1]benzothiopyran-4-one; benzaldehyde; thiourea at 80℃; for 0.333333h; Ionic liquid;
Stage #2: 4-chlorobenzoylmethyl bromide at 80℃; for 1h; Ionic liquid;
92%
2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

benzaldehyde
100-52-7

benzaldehyde

thiourea
17356-08-0

thiourea

4-(bromoacetyl)toluene
619-41-0

4-(bromoacetyl)toluene

7-phenyl-9-(p-tolyl)-6,7-dihydrothiazolo[3,2-a]thiochromeno[4,3-d]pyrimidine

7-phenyl-9-(p-tolyl)-6,7-dihydrothiazolo[3,2-a]thiochromeno[4,3-d]pyrimidine

Conditions
ConditionsYield
Stage #1: 2,3-dihydro-4H-[1]benzothiopyran-4-one; benzaldehyde; thiourea at 80℃; for 0.333333h; Ionic liquid;
Stage #2: 4-(bromoacetyl)toluene at 80℃; for 1h; Ionic liquid;
92%
2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

4-methyl-benzaldehyde
104-87-0

4-methyl-benzaldehyde

thiourea
17356-08-0

thiourea

para-bromophenacyl bromide
99-73-0

para-bromophenacyl bromide

9-(4-bromophenyl)-7-(p-tolyl)-6,7-dihydrothiazolo[3,2-a]thiochromeno[4,3-d]pyrimidine

9-(4-bromophenyl)-7-(p-tolyl)-6,7-dihydrothiazolo[3,2-a]thiochromeno[4,3-d]pyrimidine

Conditions
ConditionsYield
Stage #1: 2,3-dihydro-4H-[1]benzothiopyran-4-one; 4-methyl-benzaldehyde; thiourea at 80℃; for 0.333333h; Ionic liquid;
Stage #2: para-bromophenacyl bromide at 80℃; for 1h; Ionic liquid;
92%
2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

4-chlorobenzaldehyde
104-88-1

4-chlorobenzaldehyde

4-Nitrophenacyl bromide
99-81-0

4-Nitrophenacyl bromide

thiourea
17356-08-0

thiourea

7-(4-chlorophenyl)-9-(4-nitrophenyl)-6,7-dihydrothiazolo[3,2-a]thiochromeno[4,3-d]pyrimidine

7-(4-chlorophenyl)-9-(4-nitrophenyl)-6,7-dihydrothiazolo[3,2-a]thiochromeno[4,3-d]pyrimidine

Conditions
ConditionsYield
Stage #1: 2,3-dihydro-4H-[1]benzothiopyran-4-one; 4-chlorobenzaldehyde; thiourea at 80℃; for 0.333333h; Ionic liquid;
Stage #2: 4-Nitrophenacyl bromide at 80℃; for 1h; Ionic liquid;
92%
2,3-dihydro-4H-[1]benzothiopyran-4-one
3528-17-4

2,3-dihydro-4H-[1]benzothiopyran-4-one

4-methoxy-benzaldehyde
123-11-5

4-methoxy-benzaldehyde

thiourea
17356-08-0

thiourea

4-(4-methoxyphenyl)-3,4-dihydro-1H-thiochromeno[4,3-d]pyrimidine-2(5H)-thione
137985-64-9

4-(4-methoxyphenyl)-3,4-dihydro-1H-thiochromeno[4,3-d]pyrimidine-2(5H)-thione

Conditions
ConditionsYield
With 1-butyl-3-methylimidazolium hydrogen sulfate at 70℃; for 1h; Green chemistry;92%

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