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Hangzhou Think Chemical Co. Ltd

(11beta,17alpha)-11,17-Dihydroxy-3-oxoandrosta-1,4-diene-17-carboxylic acid[CAS:37927-29-0] Conclusion:It Complies with the Enterprise’s Standard . HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of tra

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

(11beta,17alpha)-11,17-dihydroxy-3-oxoandrosta-1,4-diene-17-carboxylic acid 37927-29-0

Cas:37927-29-0

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for the fine chemicals, ph

(11beta,17alpha)-11,17-dihydroxy-3-oxoandrosta-1,4-diene-17-carboxylic acid

Cas:37927-29-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Androsta-1,4-diene-17-carboxylicacid, 11,17-dihydroxy-3-oxo-, (11b,17a)- 37927-29-0

Cas:37927-29-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

(11beta,17alpha)-11,17-dihydroxy-3-oxoandrosta-1,4-diene-17-carboxylic acid CAS: 37927-29-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical

(11beta,17alpha)-11,17-dihydroxy-3-oxoandrosta-1,4-diene-17-carboxylic acid CAS: 37927-29-0

Cas:37927-29-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shaanxi Cuicheng Biomedical Technology Co., Ltd.

Why Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu

(11beta,17alpha)-11,17-dihydroxy-3-oxoandrosta-1,4-diene-17-carboxylic acid

Cas:37927-29-0

Min.Order:1 Gram

Negotiable

Type:Other

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

(11beta,17alpha)-11,17-Dihydroxy-3-oxoandrosta-1

Cas:37927-29-0

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

(11beta,17alpha)-11,17-Dihydroxy-3-oxoandrosta-1

Cas:37927-29-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so

(11beta,17alpha)-11,17-Dihydroxy-3-oxoandrosta-1

Cas:37927-29-0

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

Androsta-1,4-diene-17-carboxylicacid, 11,17-dihydroxy-3-oxo-, (11b,17a)-

Cas:37927-29-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

Product Name: (11beta,17alpha)-11,17-dihydroxy-3-oxoandrosta-1,4-diene-17-carboxylic acid Synonyms: (11beta,17alpha)-11,17-dihydroxy-3-oxoandrosta-1,…Appearance:Solid powder Storage:Sealed,light and oxygen resistant Package:aluminum foil bag,carton

(11beta,17alpha)-11,17-Dihydroxy-3-oxoandrosta-1

Cas:37927-29-0

Min.Order:0

Negotiable

Type:Other

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GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

(11β,17α)-11,17-dihydroxy-3-oxoandrosta-1,4-diene-17-carboxylic acid

Cas:37927-29-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

hight degree of purity Application:Fine chemical intermediates, used as the main raw material for he synthesis of various pesticides, medicines, surfactants, polymer monomers, Ond Ontifungal agents

Androsta-1,4-diene-17-carboxylicacid, 11,17-dihydroxy-3-oxo-, (11b,17a)-

Cas:37927-29-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:Pharm intermediate

Prednisolone Impurity 6

Cas:37927-29-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

(11BETA,17A)-11,17-DIHYDROXY-3-OXOANDROSTA-1,4-DIENE-17-CARBOXYLIC ACIDCASAppearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

Chemlyte Solutions

factory?direct?sale Application:Fine chemical intermediates, used as the main raw material for the synthesis of various pesticides, medicines, surfactants, polymer monomers, and antifungal agents

Chemsigma International Co.,Ltd.

bulk?production Application:Pharmaceutical intermediates

(11beta,17alpha)-11,17-dihydroxy-3-oxoandrosta-1,4-diene-17-carboxylic acid

Cas:37927-29-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

(11beta,17alpha)-11,17-dihydroxy-3-oxoandrosta-1,4-diene-17-carboxylic acid

Cas:37927-29-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hebei youze Biotechnology Co.,Ltd

1. Professional manufacturing and R&D department 2.Sperior quality and good package 3.Fast and safety delivery by well-reputed shipping line; 4.Better payment term and cost advantage: the origin of medicinal materials for the low purchase pric

Toda Biotechnology Co., Limited.

Todachem specialize in exporting chemicals for 10 years, we manufacture and distribute high quality pharmaceutical APIs, intermediates, special chemicals, active molecule and other fine chemicals. We have our research laboratory and more than 100 n

Hangzhou Neway Chemicals Co., Ltd.

We supply1.in very competitive price; 2.Quality Guaranteed; 3.Fast Delivery; 4.credit support Application:APIs and Chemical Intermediates

(11beta,17alpha)-11,17-dihydroxy-3-oxoandrosta-1,4-diene-17-carboxylic acid

Cas:37927-29-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Nanjing Sunsure Chemical Technology Co., Ltd

Nanjing Sunsure Chemical Technology Co., Ltd., established in 2009, has expanded a compositive entity from initially only as a small manufacturer. The company dedicated to the development, production and marketing of chemicals. Sunsure covers whole

11-Beta,?17-Alpha-Dihydroxy-3-Oxoandrost-1,4-Diene-17-Carboxylic?Acd 37927-29-0 supplier

Cas:37927-29-0

Min.Order:1 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai united Scientific Co.,Ltd.

United Scientific Company Located in Shanghai of China , is a competitive player in the global specialty and fine chemical market. Fenghua has both the expertise and flexibility to produce a wide range of chemicals. Focusing on developing the innovat

Androsta-1,4-diene-17-carboxylicacid, 11,17-dihydroxy-3-oxo-, (11b,17a)-

Cas:37927-29-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Simson Pharma Limited

The system can just identify the products information in first sheet, it is not be permitted to add or edit new sheet by userself.Our products are required in MG to Gram only. · Pharmaceutical Reference Standards· Traceable workin

Prednisolone Impurity B

Cas:37927-29-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Topbatt Chemical Co., Ltd.

Topbatt Chemical Co., Ltd., Established in 2019, located in Shenzhen, Guangdong Province, is a Manufacturer and Trading company which specialized in fine chemicals like Pharmaceutical Reference Standards and Stable Isotopes. Our Stable Isotopes produ

Prednisolone Impurity B (Carboxylic Acid)

Cas:37927-29-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI ZZBIO CO., LTD.

Comprehensive range product line, COA with HPLC, MS and NMR spectra. Package:1mg Application:pharmaceutical industry, biotech industry, research institutions.

[2H4]-11-beta, 17-alpha-Dihydroxy-3-oxoandrost-1,4-diene-17-carboxylic acid

Cas:37927-29-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shenzhen Sumshine Biotech Co., Ltd.

1. Our staff are all biomedical related majors with rich experience in the pharmaceutical industry, and can provide you with more professional services.2. Our supplier has a good quality management system, and the quality of products is reliable and

Prednisolone Impurity B (Carboxylic Acid)

Cas:37927-29-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Chemical Co.Ltd

Manufacturer,strong R&D,professional team Storage:Store in a cool, dry place. Store in a tightly closed container. Package:according to your requirement Application:ZhiShang Chemical is owned by ZhiShang Group, is a professional new-type chemicals en

Androsta-1,4-diene-17-carboxylicacid, 11,17-dihydroxy-3-oxo-, (11b,17a)-

Cas:37927-29-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Henan Fine Chemicals Co., Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & CommercialHenan Fine Chemicals Co., LTD. is a diversified technology - oriented integrated company, which mainly concentrates on fine chemicals. Our company is committed to becom

(11beta,17alpha)-11,17-dihydroxy-3-oxoandrosta-1,4-diene-17-carboxylic acid

Cas:37927-29-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

prednisolon
50-24-8

prednisolon

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

Conditions
ConditionsYield
With periodic acid In tetrahydrofuran; methanol at 20℃; for 2h;100%
With sodium periodate; sulfuric acid In methanol; water at 20℃; for 16h; Inert atmosphere;98.8%
With sodium periodate In methanol; water for 0.5h; Heating; Large scale;97%
C20H25BrO5

C20H25BrO5

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

Conditions
ConditionsYield
With hydrogenchloride; chromium chloride; mercaptoacetic acid; zinc In ethanol; water at 10 - 30℃; for 0.5h; Temperature; Inert atmosphere;98%
Loteprednol etabonate
82034-46-6

Loteprednol etabonate

A

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

B

17α-ethoxycarbonyloxy-11β-hydroxy-3-oxoandrosta-1,4-diene-17β-carboxylic acid

17α-ethoxycarbonyloxy-11β-hydroxy-3-oxoandrosta-1,4-diene-17β-carboxylic acid

Conditions
ConditionsYield
With heptakis(2,6-di-O-methyl)cyclomaltoheptaose; water at 37℃; Kinetics; Activation energy; Further Variations:; Temperatures; Reagents; Solvents; Hydrolysis;
11α-hydroxy-androsta-1,4-diene-3,17-dione
898-84-0, 96893-16-2, 7801-18-5

11α-hydroxy-androsta-1,4-diene-3,17-dione

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: acetic anhydride; phosphoric acid / dichloromethane / 5 h / 0 - 5 °C / Inert atmosphere
2.1: magnesium; ethylene dibromide / tetrahydrofuran / 1 h / 50 - 60 °C / Inert atmosphere
2.2: 1 h / -5 - 5 °C / Inert atmosphere
3.1: sodium hydrogencarbonate; potassium fluoride / tetrahydrofuran / 0.5 h / 25 °C / Inert atmosphere
3.2: 5 h / 25 °C / Inert atmosphere
4.1: chromium(VI) oxide; sulfuric acid / acetone; water / 0 - 25 °C
5.1: perchloric acid; N-bromoacetamide / acetone / 3.33 h / -5 - 5 °C / Inert atmosphere
6.1: mercaptoacetic acid; chromium chloride; zinc; hydrogenchloride / water; ethanol / 0.5 h / 10 - 30 °C / Inert atmosphere
View Scheme
androsta-1,4,9(11)-triene-3,17-dione
15375-21-0

androsta-1,4,9(11)-triene-3,17-dione

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: magnesium; ethylene dibromide / tetrahydrofuran / 1 h / 50 - 60 °C / Inert atmosphere
1.2: 1 h / -5 - 5 °C / Inert atmosphere
2.1: sodium hydrogencarbonate; potassium fluoride / tetrahydrofuran / 0.5 h / 25 °C / Inert atmosphere
2.2: 5 h / 25 °C / Inert atmosphere
3.1: chromium(VI) oxide; sulfuric acid / acetone; water / 0 - 25 °C
4.1: perchloric acid; N-bromoacetamide / acetone / 3.33 h / -5 - 5 °C / Inert atmosphere
5.1: mercaptoacetic acid; chromium chloride; zinc; hydrogenchloride / water; ethanol / 0.5 h / 10 - 30 °C / Inert atmosphere
View Scheme
C25H38O3Si

C25H38O3Si

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: sodium hydrogencarbonate; potassium fluoride / tetrahydrofuran / 0.5 h / 25 °C / Inert atmosphere
1.2: 5 h / 25 °C / Inert atmosphere
2.1: chromium(VI) oxide; sulfuric acid / acetone; water / 0 - 25 °C
3.1: perchloric acid; N-bromoacetamide / acetone / 3.33 h / -5 - 5 °C / Inert atmosphere
4.1: mercaptoacetic acid; chromium chloride; zinc; hydrogenchloride / water; ethanol / 0.5 h / 10 - 30 °C / Inert atmosphere
View Scheme
C20H26O3

C20H26O3

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: chromium(VI) oxide; sulfuric acid / acetone; water / 0 - 25 °C
2: perchloric acid; N-bromoacetamide / acetone / 3.33 h / -5 - 5 °C / Inert atmosphere
3: mercaptoacetic acid; chromium chloride; zinc; hydrogenchloride / water; ethanol / 0.5 h / 10 - 30 °C / Inert atmosphere
View Scheme
chloro-methylsulfanyl-methane
2373-51-5

chloro-methylsulfanyl-methane

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

methylthiomethyl 11β,17α-dihydroxy-3-oxo-androst-1,4-diene-17β-carboxylate

methylthiomethyl 11β,17α-dihydroxy-3-oxo-androst-1,4-diene-17β-carboxylate

Conditions
ConditionsYield
With triethylamine98%
(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

chloroformic acid ethyl ester
541-41-3

chloroformic acid ethyl ester

17α-[(ethoxycarbonyl)oxy]-11β-hydroxy-3-oxoandrosta-1,4-diene-17β-carboxylic ethoxycarboxylic anhydride

17α-[(ethoxycarbonyl)oxy]-11β-hydroxy-3-oxoandrosta-1,4-diene-17β-carboxylic ethoxycarboxylic anhydride

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 10℃; for 0.5h; Large scale;96%
With tetra(n-butyl)ammonium hydrogensulfate; sodium hydrogencarbonate In dichloromethane at 20℃; for 3h; Time;90.2%
dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

tetra(n-butyl)ammonium hydrogensulfate
32503-27-8

tetra(n-butyl)ammonium hydrogensulfate

17α-dichloroacetoxy-11β-hydroxyandrosta-1,4-diene-3-one-17β-carboxylic acid
199331-37-8

17α-dichloroacetoxy-11β-hydroxyandrosta-1,4-diene-3-one-17β-carboxylic acid

Conditions
ConditionsYield
With sodium hydrogencarbonate In methanol; dichloromethane; water95%
With sodium hydrogencarbonate In methanol; dichloromethane; water95%
With sodium hydrogencarbonate In dichloromethane; water
With sodium hydrogencarbonate In dichloromethane; water
dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

17α-dichloroacetoxy-11β-hydroxyandrosta-1,4-diene-3-one-17β-carboxylic acid
199331-37-8

17α-dichloroacetoxy-11β-hydroxyandrosta-1,4-diene-3-one-17β-carboxylic acid

Conditions
ConditionsYield
With potassium hydrogencarbonate In dichloromethane; water for 2h;93%
With potassium hydrogencarbonate In dichloromethane; water for 2.5h;93%
(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

11β-hydroxy-17-methyl-18-norandrosta-1,4,13(17)-trien-3-one

11β-hydroxy-17-methyl-18-norandrosta-1,4,13(17)-trien-3-one

Conditions
ConditionsYield
With dicyclohexyl-carbodiimide In 1,4-dioxane; acetonitrile for 1h; Ambient temperature;88%
9-deoxo-9a-aza-9a-demethyl-9a-(3-aminopropyl)-9a-homoerythromycin A
92594-46-2

9-deoxo-9a-aza-9a-demethyl-9a-(3-aminopropyl)-9a-homoerythromycin A

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

C60H101N3O16
442638-01-9

C60H101N3O16

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane at 0 - 20℃; for 18h; Inert atmosphere;88%
(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

diisopropyl-carbodiimide
693-13-0

diisopropyl-carbodiimide

(17R)-3'-isopropyl-2'-isopropylimino-11β-hydroxyspiro-3,4'-dione

(17R)-3'-isopropyl-2'-isopropylimino-11β-hydroxyspiro-3,4'-dione

Conditions
ConditionsYield
With copper dichloride In 1,4-dioxane; acetonitrile for 1h; Ambient temperature;86%
(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

2-(4-methoxyphenoxy)ethylamine
50800-92-5

2-(4-methoxyphenoxy)ethylamine

C29H37NO6

C29H37NO6

Conditions
ConditionsYield
Stage #1: (1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 1h; Inert atmosphere;
Stage #2: 2-(4-methoxyphenoxy)ethylamine With triethylamine In N,N-dimethyl-formamide at 60℃; for 1.5h; Inert atmosphere;
75%
(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

(L)-phenylalanine ethyl ester hydrochloride
3182-93-2

(L)-phenylalanine ethyl ester hydrochloride

ethyl 2-(11β,17α-dihydroxy-3-oxo-androst-1,4-dien-17β-carboxamido)-3-phenylpropionate

ethyl 2-(11β,17α-dihydroxy-3-oxo-androst-1,4-dien-17β-carboxamido)-3-phenylpropionate

Conditions
ConditionsYield
Stage #1: (1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid With benzotriazol-1-ol; dicyclohexyl-carbodiimide In N,N-dimethyl-formamide at 0 - 8℃; for 16h;
Stage #2: (L)-phenylalanine ethyl ester hydrochloride With triethylamine In N,N-dimethyl-formamide at 0 - 8℃; for 16h;
70%
(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

diisopropyl-carbodiimide
693-13-0

diisopropyl-carbodiimide

(17R)-3'-isopropyl-11β-hydroxyspiro-2',3,4'-trione

(17R)-3'-isopropyl-11β-hydroxyspiro-2',3,4'-trione

Conditions
ConditionsYield
With water In N,N-dimethyl-formamide for 7h; Ambient temperature;66%
di-p-tolylcarbodiimide
726-42-1

di-p-tolylcarbodiimide

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

11β,17α-dihydroxy-3-oxo-N-p-tolyl-N-(p-tolylaminocarbonyl)androsta-1,4-diene-17-carboxamide

11β,17α-dihydroxy-3-oxo-N-p-tolyl-N-(p-tolylaminocarbonyl)androsta-1,4-diene-17-carboxamide

Conditions
ConditionsYield
With 1,4-diaza-bicyclo[2.2.2]octane In acetonitrile at 80℃; for 1h;63%
(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

glycine ethyl ester hydrochloride
5680-79-5

glycine ethyl ester hydrochloride

methyl 2-(11β,17α-dihydroxy-3-oxo-androst-1,4-dien-17β-carboxamido)acetate

methyl 2-(11β,17α-dihydroxy-3-oxo-androst-1,4-dien-17β-carboxamido)acetate

Conditions
ConditionsYield
Stage #1: (1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid With benzotriazol-1-ol; dicyclohexyl-carbodiimide In N,N-dimethyl-formamide at 0 - 8℃; for 16h;
Stage #2: glycine ethyl ester hydrochloride With triethylamine In N,N-dimethyl-formamide at 0 - 8℃; for 16h;
57%
(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

methyl [4-(3-aminopropoxy)benzoate]
85873-34-3

methyl [4-(3-aminopropoxy)benzoate]

C31H39NO7

C31H39NO7

Conditions
ConditionsYield
Stage #1: (1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 1h; Inert atmosphere;
Stage #2: methyl [4-(3-aminopropoxy)benzoate] In N,N-dimethyl-formamide at 60℃; for 2.5h; Inert atmosphere;
54%
(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

6α,11β,17α-trihydroxyandrosta-1,4-dien-3-one-17β-carboxylic acid

6α,11β,17α-trihydroxyandrosta-1,4-dien-3-one-17β-carboxylic acid

Conditions
ConditionsYield
With selenium(IV) oxide In 1,4-dioxane for 12h; Heating;53.9%
(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

1-(3-aminopropoxy)-3-methoxybenzene
6451-26-9

1-(3-aminopropoxy)-3-methoxybenzene

C30H39NO6

C30H39NO6

Conditions
ConditionsYield
Stage #1: (1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 1h; Inert atmosphere;
Stage #2: 1-(3-aminopropoxy)-3-methoxybenzene With triethylamine In N,N-dimethyl-formamide at 60℃; for 2.5h; Inert atmosphere;
53%
(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

ethyl β-alaninate hydrochloride
4244-84-2

ethyl β-alaninate hydrochloride

ethyl 3-(11β,17α-dihydroxy-3-oxo-androst-1,4-dien-17β-carboxamido)propionate

ethyl 3-(11β,17α-dihydroxy-3-oxo-androst-1,4-dien-17β-carboxamido)propionate

Conditions
ConditionsYield
Stage #1: (1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid With benzotriazol-1-ol; dicyclohexyl-carbodiimide In N,N-dimethyl-formamide at 0 - 8℃; for 16h;
Stage #2: ethyl β-alaninate hydrochloride With triethylamine In N,N-dimethyl-formamide at 0 - 8℃; for 16h;
51%
di-p-tolylcarbodiimide
726-42-1

di-p-tolylcarbodiimide

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

(17R)-3'-p-tolyl-11β-hydroxyspiro-2',3,4'-trione

(17R)-3'-p-tolyl-11β-hydroxyspiro-2',3,4'-trione

Conditions
ConditionsYield
With water In N,N-dimethyl-formamide for 168h; Ambient temperature;50%
chloroiodoacetyl chloride
827313-06-4

chloroiodoacetyl chloride

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

17α-chloroiodoacetoxy-11β-hydroxyandrosta-1,4-dien-3-one-17β-carboxylic acid
750645-43-3

17α-chloroiodoacetoxy-11β-hydroxyandrosta-1,4-dien-3-one-17β-carboxylic acid

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 2.5h;49%
(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

dicyclohexyl-carbodiimide
538-75-0

dicyclohexyl-carbodiimide

(17R)-3'-cyclohexyl-11β-hydroxyspiro-2',3,4'-trione

(17R)-3'-cyclohexyl-11β-hydroxyspiro-2',3,4'-trione

Conditions
ConditionsYield
With water In N,N-dimethyl-formamide for 7h; Ambient temperature;48%
(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

Trichloroacetyl chloride
76-02-8

Trichloroacetyl chloride

17α-trichloroacetoxy-11β-hydroxyandrosta-1,4-dien-3-one-17β-carboxylic acid
750645-44-4

17α-trichloroacetoxy-11β-hydroxyandrosta-1,4-dien-3-one-17β-carboxylic acid

Conditions
ConditionsYield
With potassium hydrogencarbonate In dichloromethane; water for 2h;48%
(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride
25952-53-8

1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride

(17R)-2'-ethylimino-11β-hydroxy-3'-dimethylaminopropylspiro-2',3,4'-trione

(17R)-2'-ethylimino-11β-hydroxy-3'-dimethylaminopropylspiro-2',3,4'-trione

Conditions
ConditionsYield
In N,N-dimethyl-formamide for 3h; Ambient temperature;47%
(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

dicyclohexyl-carbodiimide
538-75-0

dicyclohexyl-carbodiimide

(17R)-3'-cyclohexyl-2'-cyclohexylimino-11β-hydroxyspiro-3,4'-dione

(17R)-3'-cyclohexyl-2'-cyclohexylimino-11β-hydroxyspiro-3,4'-dione

Conditions
ConditionsYield
With copper dichloride In 1,4-dioxane; acetonitrile for 1h; Ambient temperature;47%
(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

ethyl iodide
75-03-6

ethyl iodide

ethyl 11β,17α-dihydroxyandrosta-1,4-dien-3-one-17β-carboxylate
182069-13-2

ethyl 11β,17α-dihydroxyandrosta-1,4-dien-3-one-17β-carboxylate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 1.5h;45%
formic acid
64-18-6

formic acid

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

17α-formyloxy-11β-hydroxyandrosta-1,4-dien-3-one-17β-carboxylic acid

17α-formyloxy-11β-hydroxyandrosta-1,4-dien-3-one-17β-carboxylic acid

Conditions
ConditionsYield
With acetic anhydride In pyridine for 7h; Heating;39%
(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

chloroacetyl chloride
79-04-9

chloroacetyl chloride

17α-chloroacetoxy-11β-hydroxyandrosta-1,4-dien-3-one-17β-carboxylic acid
750645-47-7

17α-chloroacetoxy-11β-hydroxyandrosta-1,4-dien-3-one-17β-carboxylic acid

Conditions
ConditionsYield
With potassium hydrogencarbonate In dichloromethane; water for 2h;26%
(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

Δ1-CA-Me
10486-89-2

Δ1-CA-Me

Conditions
ConditionsYield
In methanol; diethyl ether
(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

β‐cyclodextrin
7585-39-9

β‐cyclodextrin

2C42H70O35*C20H26O5

2C42H70O35*C20H26O5

Conditions
ConditionsYield
In water at 25℃; for 168h;
(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid
37927-29-0

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0 02,7. 011,15]heptadeca-3,6-diene-14-carboxylic acid

cyclomaltooctaose
17465-86-0

cyclomaltooctaose

3C48H80O40*2C20H26O5

3C48H80O40*2C20H26O5

Conditions
ConditionsYield
In water at 25℃; for 168h;

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