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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for the fine c

4-Bromo-9H-fluoren-9-one

Cas:4269-17-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

4-bromo-9H-fluoren-9-one

Cas:4269-17-4

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price OLED 99% 4269-17-4 4-bromo-9H-fluoren-9-one Manufacturer

Cas:4269-17-4

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Shanghai Hohance Chemical Co., ltd

4-bromo-9H-fluoren-9-one company introduction Hohance Chemical Co., Ltd. is a researchbased pharmaceutical & chemical corporation focusing on the custom synthesis service of novel products in the field of pharmaceuticals. With our R&D cente

4-bromo-9H-fluoren-9-one

Cas:4269-17-4

Min.Order:50 Gram

FOB Price: $11.0 / 15.0

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so

NSC81339

Cas:4269-17-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Jinan Finer Chemical Co., Ltd

Product Description Product website: http://www.finerchem.com Product Name 4-bromo-9H-fluoren-9-one CAS No. 426

4-bromo-9H-fluoren-9-one

Cas:4269-17-4

Min.Order:1 Gram

FOB Price: $12.0

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 4269-17-4 with competitive price

Cas:4269-17-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

4-bromofluoren-9-one

Cas:4269-17-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

4-Bromo-9H-fluoren-9-one CAS: 4269-17-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic

4-Bromo-9H-fluoren-9-one CAS: 4269-17-4

Cas:4269-17-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

4-bromofluoren-9-one

Cas:4269-17-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

4-bromofluoren-9-one/ LIDE PHARMA- Factory supply / Best price

Cas:4269-17-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram

4-bromo-9H-fluoren-9-one CAS NO.4269-17-4

Cas:4269-17-4

Min.Order:10 Gram

Negotiable

Type:Trading Company

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Triumph International Development Limilted

Appearance:white or light yellow crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:By

4-BroMo-9-fluorenone

Cas:4269-17-4

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

4-bromofluoren-9-one

Cas:4269-17-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

4-Bromo-9H-fluoren-9-one

Cas:4269-17-4

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

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Wuhan Fortuna Chemical Co.,Ltd

1.High quality : the purity is 99% min . through multiple producing procedures. 2.Competitive price : low price because of our skilled production technolpgy ,save the production cost at most , and give big profit room to our customers 3.Safe a

4-Bromofluorenone

Cas:4269-17-4

Min.Order:0 Metric Ton

Negotiable

Type:Trading Company

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

4-bromo-9H-fluoren-9-one

Cas:4269-17-4

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

4-bromofluoren-9-one

Cas:4269-17-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

We are leading fine chemicals supplier in China with ISO certificate, Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...) 2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...) 3.OLED

NSC81339CAS NO.: 4269-17-4

Cas:4269-17-4

Min.Order:1 Gram

FOB Price: $2.0

Type:Lab/Research institutions

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TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

4-Bromo-9H-fluoren-9-one

Cas:4269-17-4

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

4269-17-4 CAS NO.4269-17-4

Cas:4269-17-4

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

inquiry

Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service an

4-bromofluorenone

Cas:4269-17-4

Min.Order:1 Gram

Negotiable

Type:Other

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Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

4-Bromofluorenone

Cas:4269-17-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe

4-Bromo-9H-fluoren-9-one

Cas:4269-17-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratoryAppearance:white to light yellow powder Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

4-Bromofluoren-9-one cas no. 4269-17-4 98%

Cas:4269-17-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Jiling Chemical Co., Ltd

factory Storage:Shading, sealed and preserved. Package:Grams, Kilograms Application:An organic synthetic intermediate used Transportation:According to customer request Port:Qingdao

4-bromofluoren-9-one

Cas:4269-17-4

Min.Order:0

Negotiable

Type:Other

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

4-bromo-9H-fluoren-9-one

Cas:4269-17-4

Min.Order:0

Negotiable

Type:Other

inquiry

Wuxi TAA Chemical Industry Co.,LTD.

1.A strong technical force and advanced processing equipments. The quality of the products has been strictly inspected and all kinds of index have reached or exceeded domestic and international standards.2. Now we have established long-term stable re

NSC81339 CAS 4269-17-4

Cas:4269-17-4

Min.Order:0

Negotiable

Type:Other

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

4-Bromo-9H-fluoren-9-one

Cas:4269-17-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

manufacture Application:The refence standard products, for lab use, also we could produce bigger quantity on yr requirement.

4-bromofluorenone

Cas:4269-17-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

bromobenzene
108-86-1

bromobenzene

3-Bromopropionyl chloride
15486-96-1

3-Bromopropionyl chloride

4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

Conditions
ConditionsYield
Stage #1: bromobenzene In dichloromethane at 5℃; for 0.5h;
Stage #2: 3-Bromopropionyl chloride In dichloromethane at 5 - 20℃; for 16h;
Stage #3: With trifluorormethanesulfonic acid In dichloromethane at 90℃; for 4h; Temperature; Reagent/catalyst;
88.5%
2'-bromo-[1,1'-biphenyl]-2-carbonitrile
54245-41-9

2'-bromo-[1,1'-biphenyl]-2-carbonitrile

4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

Conditions
ConditionsYield
With sulfuric acid; acetic acid for 12h; Reflux;80%
With dichloro bis(acetonitrile) palladium(II); water; silver trifluoroacetate In N,N-dimethyl acetamide; trifluoroacetic acid at 140℃; for 72h; Heck Reaction; Glovebox; Inert atmosphere;57%
With sulfuric acid
ethyl 2’-bromo-[1,1’-biphenyl]-2-carboxylate
690260-87-8

ethyl 2’-bromo-[1,1’-biphenyl]-2-carboxylate

4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

Conditions
ConditionsYield
With methanesulfonic acid at 100℃; for 14h;61%
9-fluorenone
486-25-9

9-fluorenone

4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

Conditions
ConditionsYield
With N-Bromosuccinimide; sulfuric acid In dichloromethane at 20℃; for 12h;47.9%
1-Bromo-2-iodobenzene
583-55-1

1-Bromo-2-iodobenzene

(S)-2-(3-bromo-2-iodophenyl)-4-isopropyl-4,5-dihydrooxazole

(S)-2-(3-bromo-2-iodophenyl)-4-isopropyl-4,5-dihydrooxazole

A

4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

B

(4S)-2-(6-bromo-2'-iodo-(1,1'-biphenyl)-2-yl)-4-isopropyl-4,5-dihydrooxazole

(4S)-2-(6-bromo-2'-iodo-(1,1'-biphenyl)-2-yl)-4-isopropyl-4,5-dihydrooxazole

Conditions
ConditionsYield
Stage #1: (S)-2-(3-bromo-2-iodophenyl)-4-isopropyl-4,5-dihydrooxazole With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.25h; Inert atmosphere;
Stage #2: 1-Bromo-2-iodobenzene In tetrahydrofuran; hexane at -78℃; Inert atmosphere;
Stage #3: With n-butyllithium In tetrahydrofuran; hexane at -78 - 25℃; for 12h; Inert atmosphere; diastereoselective reaction;
A 20%
B 46%
Stage #1: (S)-2-(3-bromo-2-iodophenyl)-4-isopropyl-4,5-dihydrooxazole With n-butyllithium In tetrahydrofuran; hexane at -78℃;
Stage #2: 1-Bromo-2-iodobenzene In tetrahydrofuran; hexane at -78℃; for 12h; Overall yield = 46 %; Overall yield = 234 mg; diastereoselective reaction;
A n/a
B n/a
furfural
98-01-1

furfural

2-bromo-2’-iodo-1,1’-biphenyl
39655-12-4

2-bromo-2’-iodo-1,1’-biphenyl

A

9-fluorenone
486-25-9

9-fluorenone

B

4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

Conditions
ConditionsYield
With chloro(1,5-cyclooctadiene)rhodium(I) dimer; 1,3-bis-(diphenylphosphino)propane; sodium carbonate In 5,5-dimethyl-1,3-cyclohexadiene at 150℃; for 48h; Inert atmosphere;A 18%
B 31%
4-bromo-9H-fluorene
19459-33-7

4-bromo-9H-fluorene

4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

4-aminofluorenone
4269-15-2

4-aminofluorenone

4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

Conditions
ConditionsYield
With hydrogen bromide Diazotization.Erhitzen mit CuBr und wss. HBr;
(2-amino-3-bromophenyl)(phenyl)methanone

(2-amino-3-bromophenyl)(phenyl)methanone

4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

4-Brom-1-amino-fluorenon-(9)
16149-47-6

4-Brom-1-amino-fluorenon-(9)

4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

Conditions
ConditionsYield
(i) NaNO2, aq. HCl, (ii) H3PO2; Multistep reaction;
2'-bromo-biphenyl-carboxylic acid-(2)

2'-bromo-biphenyl-carboxylic acid-(2)

4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

Conditions
ConditionsYield
With sulfuric acid at 45 - 50℃;
4-bromo-fluoren-9-ol
99514-93-9

4-bromo-fluoren-9-ol

4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: acetic acid; aqueous HI
2: acetic acid; Na2Cr2O7
View Scheme
1-Bromo-2-iodobenzene
583-55-1

1-Bromo-2-iodobenzene

4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: Cu
2: Py / dimethylformamide
3: aq. H2SO4
View Scheme
2,2'-dibromobiphenyl
13029-09-9

2,2'-dibromobiphenyl

4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Py / dimethylformamide
2: aq. H2SO4
View Scheme
Multi-step reaction with 2 steps
1.1: n-butyllithium / tetrahydrofuran; hexane / 0.67 h / -78 °C / Inert atmosphere
1.2: Inert atmosphere
2.1: sulfuric acid / water / 2 h / 50 °C
View Scheme
Multi-step reaction with 2 steps
1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C
1.2: 18 h / -78 - 20 °C
2.1: sulfuric acid / 2 h / 0 - 50 °C
View Scheme
1-amino-9H-fluoren-9-one
6344-62-3

1-amino-9H-fluoren-9-one

4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Br2, AcOH
2: (i) NaNO2, aq. HCl, (ii) H3PO2
View Scheme
2'-bromo-[1,1'-biphenyl]-2-carboxylic acid
69200-16-4

2'-bromo-[1,1'-biphenyl]-2-carboxylic acid

4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

Conditions
ConditionsYield
With sulfuric acid In water at 50℃; for 2h;
With sulfuric acid at 0 - 50℃; for 2h;36 g
1-Bromo-2-iodobenzene
583-55-1

1-Bromo-2-iodobenzene

o-cyanophenylboronic acid-1,3-propylene glycol ester
172732-52-4

o-cyanophenylboronic acid-1,3-propylene glycol ester

4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Pd(PPh3)2Cl2; tripotassium phosphate "n" hydrate / toluene / 12 h / 100 °C / Schlenk technique; Inert atmosphere
2: water; silver trifluoroacetate; dichloro bis(acetonitrile) palladium(II) / trifluoroacetic acid; N,N-dimethyl acetamide / 72 h / 140 °C / Glovebox; Inert atmosphere
View Scheme
2-Cyanophenylboronic acid
138642-62-3

2-Cyanophenylboronic acid

4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: toluene / 2 h / 110 °C
2: Pd(PPh3)2Cl2; tripotassium phosphate "n" hydrate / toluene / 12 h / 100 °C / Schlenk technique; Inert atmosphere
3: water; silver trifluoroacetate; dichloro bis(acetonitrile) palladium(II) / trifluoroacetic acid; N,N-dimethyl acetamide / 72 h / 140 °C / Glovebox; Inert atmosphere
View Scheme
methyl 2-iodo-3-bromobenzoate
121772-84-7

methyl 2-iodo-3-bromobenzoate

4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: tetrakis(triphenylphosphine) palladium(0) / tetrahydrofuran / 0.5 h / Inert atmosphere
1.2: 0.33 h / Reflux
2.1: sodium hydroxide; ethanol / 6 h
3.1: methanesulfonic acid / 24 h / 30 °C
View Scheme
Multi-step reaction with 3 steps
1.1: tetrakis(triphenylphosphine) palladium(0) / tetrahydrofuran / 0.5 h / Inert atmosphere
1.2: Reflux
2.1: sodium hydroxide / ethanol / 6 h / Reflux
3.1: methanesulfonic acid / 24 h / 30 °C
View Scheme
phenylboronic acid
98-80-6

phenylboronic acid

4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: tetrakis(triphenylphosphine) palladium(0) / tetrahydrofuran / 0.5 h / Inert atmosphere
1.2: 0.33 h / Reflux
2.1: sodium hydroxide; ethanol / 6 h
3.1: methanesulfonic acid / 24 h / 30 °C
View Scheme
Multi-step reaction with 3 steps
1.1: tetrakis(triphenylphosphine) palladium(0) / tetrahydrofuran / 0.5 h / Inert atmosphere
1.2: Reflux
2.1: sodium hydroxide / ethanol / 6 h / Reflux
3.1: methanesulfonic acid / 24 h / 30 °C
View Scheme
C14H11BrO2

C14H11BrO2

4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium hydroxide; ethanol / 6 h
2: methanesulfonic acid / 24 h / 30 °C
View Scheme
Multi-step reaction with 2 steps
1: sodium hydroxide / ethanol / 6 h / Reflux
2: methanesulfonic acid / 24 h / 30 °C
View Scheme
6-bromo-biphenyl-2-carboxylic acid

6-bromo-biphenyl-2-carboxylic acid

4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

Conditions
ConditionsYield
With methanesulfonic acid at 30℃; for 24h;
With methanesulfonic acid at 30℃; for 24h;
4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

phenylmagnesium bromide
100-58-3

phenylmagnesium bromide

2-bromo-9-phenyl-9H-fluoren-9-ol
736928-22-6

2-bromo-9-phenyl-9H-fluoren-9-ol

Conditions
ConditionsYield
In tetrahydrofuran at 0℃; for 0.333333h;100%
9-(2-bromophenyl)-9H-carbazole
902518-11-0

9-(2-bromophenyl)-9H-carbazole

4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

C31H18BrN

C31H18BrN

Conditions
ConditionsYield
Stage #1: 9-(2-bromophenyl)-9H-carbazole With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.5h;
Stage #2: 4-bromo-9H-fluorene-9-one In tetrahydrofuran; hexane at -78℃; for 3.67h;
Stage #3: With sulfuric acid; acetic acid for 4h; Reflux;
97%
Stage #1: 9-(2-bromophenyl)-9H-carbazole With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.5h;
Stage #2: 4-bromo-9H-fluorene-9-one In tetrahydrofuran; hexane at -78 - 20℃; for 3.66667h;
97%
Stage #1: 9-(2-bromophenyl)-9H-carbazole With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.5h;
Stage #2: 4-bromo-9H-fluorene-9-one In tetrahydrofuran; hexane at -78 - 20℃; for 3.67h;
Stage #3: With sulfuric acid; acetic acid for 4h; Reflux;
97%
Stage #1: 9-(2-bromophenyl)-9H-carbazole With n-butyllithium In tetrahydrofuran at -78℃; for 0.5h; Inert atmosphere;
Stage #2: 4-bromo-9H-fluorene-9-one In tetrahydrofuran at 20℃; for 2h; Inert atmosphere;
Stage #3: With hydrogenchloride; acetic acid for 12h; Reflux;
65%
4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

2,4,7-tribromo-9H-fluoren-9-one

2,4,7-tribromo-9H-fluoren-9-one

Conditions
ConditionsYield
With bromine In dichloromethane at 0 - 20℃; for 6h;92%
With bromine In dichloromethane at 20℃; for 6h;90%
With bromine In dichloromethane at 20℃; for 6h; Cooling with ice;90%
4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

2,3-di-(4-tert-butylphenyl)-1,4-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene

2,3-di-(4-tert-butylphenyl)-1,4-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene

4,4'-(4,4''-di-tert-butyl-[1,1':2',1''-terphenyl]-3',6'-diyl)bis(9H-fluoren-9-one)

4,4'-(4,4''-di-tert-butyl-[1,1':2',1''-terphenyl]-3',6'-diyl)bis(9H-fluoren-9-one)

Conditions
ConditionsYield
With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; potassium carbonate; XPhos In 1,4-dioxane; water at 100℃; for 24h; Suzuki Coupling; Schlenk technique; Sealed tube; Inert atmosphere;91%
4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

phenol
108-95-2

phenol

4-bromospiro[fluorene-9,9′-xanthene]

4-bromospiro[fluorene-9,9′-xanthene]

Conditions
ConditionsYield
With trichlorophosphate at 120℃;87%
With trichlorophosphate
4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

1-(2-bromophenyl)naphthalene
18937-92-3

1-(2-bromophenyl)naphthalene

C29H19BrO

C29H19BrO

Conditions
ConditionsYield
Stage #1: 1-(2-bromophenyl)naphthalene With n-butyllithium In tetrahydrofuran at -78℃; Inert atmosphere;
Stage #2: 4-bromo-9H-fluorene-9-one In tetrahydrofuran at 20℃; Inert atmosphere;
Stage #3: With water In tetrahydrofuran Inert atmosphere;
85.7%
Stage #1: 1-(2-bromophenyl)naphthalene With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 1h; Inert atmosphere;
Stage #2: 4-bromo-9H-fluorene-9-one In tetrahydrofuran; hexane at -78 - 20℃;
84%
Stage #1: 1-(2-bromophenyl)naphthalene With n-butyllithium In tetrahydrofuran at -78℃; for 2h; Inert atmosphere;
Stage #2: 4-bromo-9H-fluorene-9-one In tetrahydrofuran at -78 - 20℃; for 12h; Inert atmosphere;
Stage #3: With hydrogenchloride In tetrahydrofuran; water for 0.5h; Inert atmosphere;
4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

2-bromo-4,4’-dichloro-1,1’-biphenyl
179526-95-5

2-bromo-4,4’-dichloro-1,1’-biphenyl

C25H16BrClO

C25H16BrClO

Conditions
ConditionsYield
Stage #1: 2-bromo-4,4’-dichloro-1,1’-biphenyl With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.5h;
Stage #2: 4-bromo-9H-fluorene-9-one In tetrahydrofuran; hexane at 20℃; for 1h;
85%
4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

phenylboronic acid
98-80-6

phenylboronic acid

4-phenyl-9H-fluoren-9-one
4269-14-1

4-phenyl-9H-fluoren-9-one

Conditions
ConditionsYield
With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; potassium carbonate In N,N-dimethyl-formamide at 150℃; Suzuki-Miyaura Coupling; Inert atmosphere;84%
4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

2-nitrophenylboronic acid
5570-19-4

2-nitrophenylboronic acid

C19H11NO3

C19H11NO3

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); bis(tri-t-butylphosphine)palladium(0); potassium carbonate In tetrahydrofuran; water for 2h; Reflux;84%
9-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-9H-carbazole
785051-54-9

9-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-9H-carbazole

4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

4-(4-(9Hcarbazol-9-yl)phenyl)-9H-fluoren-9-one

4-(4-(9Hcarbazol-9-yl)phenyl)-9H-fluoren-9-one

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In ethanol; water; toluene at 100℃; Suzuki-Miyaura Coupling; Inert atmosphere;82%
2-(9,9'-spirobi[fluoren]-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
1161009-89-7

2-(9,9'-spirobi[fluoren]-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

4-(9,9'-spirobifluorene-4-yl)-9H-fluoren-9-one
1257321-43-9

4-(9,9'-spirobifluorene-4-yl)-9H-fluoren-9-one

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In tetrahydrofuran; water for 48h; Suzuki coupling; Reflux; Inert atmosphere;81%
4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

2-(2-bromophenyl)dibenzo[b,e][1,4]dioxine

2-(2-bromophenyl)dibenzo[b,e][1,4]dioxine

4-bromo-9-(2-(dibenzo[b,e][1,4]dioxin-2-yl)phenyl)-9H-fluoren-9-ol

4-bromo-9-(2-(dibenzo[b,e][1,4]dioxin-2-yl)phenyl)-9H-fluoren-9-ol

Conditions
ConditionsYield
Stage #1: 2-(2-bromophenyl)dibenzo[b,e][1,4]dioxine With n-butyllithium In tetrahydrofuran at -78℃; for 1h;
Stage #2: 4-bromo-9H-fluorene-9-one In tetrahydrofuran at 20℃; for 3h;
80%
4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

2,5-di-(4-tert-butylphenyl)-1,4-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene

2,5-di-(4-tert-butylphenyl)-1,4-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene

4,4'-(4,4''-di-tert-butyl-[1,1':4',1''-terphenyl]-2',5'-diyl)bis(9H-fluoren-9-one)

4,4'-(4,4''-di-tert-butyl-[1,1':4',1''-terphenyl]-2',5'-diyl)bis(9H-fluoren-9-one)

Conditions
ConditionsYield
With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; potassium carbonate; XPhos In 1,4-dioxane; water at 100℃; for 24h; Suzuki Coupling; Schlenk technique; Sealed tube; Inert atmosphere;79%
4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

C18H11Br

C18H11Br

C31H17Br

C31H17Br

Conditions
ConditionsYield
Stage #1: C18H11Br With n-butyllithium In tetrahydrofuran; hexane at -78 - 70℃; for 0.5h; Inert atmosphere;
Stage #2: 4-bromo-9H-fluorene-9-one In tetrahydrofuran; hexane for 1.5h; Inert atmosphere;
Stage #3: With hydrogenchloride; acetic acid for 4h; Reflux;
78%
2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
61676-62-8

2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

2-(9,9'-spirobi[fluoren]-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
1161009-89-7

2-(9,9'-spirobi[fluoren]-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Conditions
ConditionsYield
With n-butyllithium In tetrahydrofuran at -78 - 20℃; for 1h; Inert atmosphere;77%
4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

1-(2-bromophenyl)naphthalene
18937-92-3

1-(2-bromophenyl)naphthalene

C29H17Br

C29H17Br

Conditions
ConditionsYield
Stage #1: 1-(2-bromophenyl)naphthalene With n-butyllithium In tetrahydrofuran at -78℃; for 1h;
Stage #2: 4-bromo-9H-fluorene-9-one In tetrahydrofuran at 18 - 28℃; for 12h;
Stage #3: With hydrogenchloride; acetic acid at 120℃; for 5h;
75%
4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

N-(2-bromophenyl)-N-phenylbenzenamine
78600-31-4

N-(2-bromophenyl)-N-phenylbenzenamine

4'-bromo-10-phenyl-10H-spiro[acridine-9,9'-fluorene]

4'-bromo-10-phenyl-10H-spiro[acridine-9,9'-fluorene]

Conditions
ConditionsYield
Stage #1: N-(2-bromophenyl)-N-phenylbenzenamine With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 1h; Inert atmosphere; Schlenk technique; Glovebox;
Stage #2: 4-bromo-9H-fluorene-9-one In tetrahydrofuran; hexane at -78 - 25℃; for 21h; Inert atmosphere; Schlenk technique; Glovebox;
73%
Stage #1: N-(2-bromophenyl)-N-phenylbenzenamine With n-butyllithium In tetrahydrofuran; hexane at -78℃; Inert atmosphere; Schlenk technique;
Stage #2: 4-bromo-9H-fluorene-9-one In tetrahydrofuran; hexane at -78 - 20℃; for 13h; Friedel-Crafts Alkylation; Inert atmosphere; Schlenk technique;
Stage #3: With hydrogenchloride; acetic acid In water for 2h; Reflux;
56%
Stage #1: 4-bromo-9H-fluorene-9-one; N-(2-bromophenyl)-N-phenylbenzenamine With n-butyllithium In tetrahydrofuran
Stage #2: With hydrogenchloride; acetic acid
4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

2-iodobiphenyl
2113-51-1

2-iodobiphenyl

C25H17BrO

C25H17BrO

Conditions
ConditionsYield
Stage #1: 2-iodobiphenyl With n-butyllithium In tetrahydrofuran at -78℃; for 1h;
Stage #2: 4-bromo-9H-fluorene-9-one In tetrahydrofuran
73%
4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

C36H26N4

C36H26N4

C49H32N4O

C49H32N4O

Conditions
ConditionsYield
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium t-butanolate In toluene for 14h; Inert atmosphere; Reflux;73%
4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

C18H11Br

C18H11Br

C31H17Br

C31H17Br

Conditions
ConditionsYield
Stage #1: C18H11Br With n-butyllithium In tetrahydrofuran; hexane at -78 - -70℃; for 0.5h; Inert atmosphere;
Stage #2: 4-bromo-9H-fluorene-9-one In tetrahydrofuran; hexane at -70 - 20℃; for 1.5h; Inert atmosphere;
Stage #3: With hydrogenchloride; acetic acid In water for 4h; Reflux;
73%
9-(2-bromophenyl)-9H-carbazole
902518-11-0

9-(2-bromophenyl)-9H-carbazole

4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

C31H20BrNO

C31H20BrNO

Conditions
ConditionsYield
Stage #1: 9-(2-bromophenyl)-9H-carbazole With n-butyllithium In tetrahydrofuran at -78℃; for 0.5h;
Stage #2: 4-bromo-9H-fluorene-9-one In tetrahydrofuran at -78 - 20℃;
72%
With n-butyllithium In tetrahydrofuran at -78℃;
4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

10-(2-bromophenyl)-10H-phenoxazine
131013-62-2

10-(2-bromophenyl)-10H-phenoxazine

4-bromooxacyclospirofluorenetriphenylamine

4-bromooxacyclospirofluorenetriphenylamine

Conditions
ConditionsYield
Stage #1: 10-(2-bromophenyl)-10H-phenoxazine With n-butyllithium In tetrahydrofuran at -78℃; for 1h; Inert atmosphere;
Stage #2: 4-bromo-9H-fluorene-9-one In tetrahydrofuran at -78 - 20℃; for 13h; Inert atmosphere;
70%
Stage #1: 10-(2-bromophenyl)-10H-phenoxazine With n-butyllithium In tetrahydrofuran at -78℃; for 1h; Inert atmosphere;
Stage #2: 4-bromo-9H-fluorene-9-one In tetrahydrofuran at 20℃; for 2h; Inert atmosphere;
Stage #3: With hydrogenchloride; acetic acid for 12h; Reflux;
62%
4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

1-(2-bromophenoxy)naphthalene

1-(2-bromophenoxy)naphthalene

4-bromo-9-(2-(naphthalen-1-yloxy)phenyl)-9H-fluoren-9-ol

4-bromo-9-(2-(naphthalen-1-yloxy)phenyl)-9H-fluoren-9-ol

Conditions
ConditionsYield
Stage #1: 1-(2-bromophenoxy)naphthalene With n-butyllithium In tetrahydrofuran at -78℃; for 3.5h; Inert atmosphere;
Stage #2: 4-bromo-9H-fluorene-9-one With n-butyllithium In tetrahydrofuran for 12h; Inert atmosphere;
67%
4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

C18H13Br

C18H13Br

C31H19Br

C31H19Br

Conditions
ConditionsYield
Stage #1: C18H13Br With n-butyllithium In tetrahydrofuran; hexane at -78 - -70℃; for 0.5h; Inert atmosphere;
Stage #2: 4-bromo-9H-fluorene-9-one In tetrahydrofuran; hexane at -70 - 20℃; for 1.5h; Inert atmosphere;
Stage #3: With hydrogenchloride; acetic acid In water for 4h; Reflux;
66%
4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

4-(2-bromophenyl)-dibenzothiophene
143546-42-3

4-(2-bromophenyl)-dibenzothiophene

C31H17BrS

C31H17BrS

Conditions
ConditionsYield
Stage #1: 4-(2-bromophenyl)-dibenzothiophene With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 1h;
Stage #2: 4-bromo-9H-fluorene-9-one In tetrahydrofuran; hexane at 20℃;
Stage #3: With hydrogenchloride In ethanol at 75℃;
65%
4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

2-bromo-3-phenylfuran

2-bromo-3-phenylfuran

4-bromospiro[fluorene-9,8'-indeno[2,1-b]furan]

4-bromospiro[fluorene-9,8'-indeno[2,1-b]furan]

Conditions
ConditionsYield
Stage #1: 2-bromo-3-phenylfuran With magnesium In tetrahydrofuran at 40℃; for 1h; Inert atmosphere;
Stage #2: 4-bromo-9H-fluorene-9-one In tetrahydrofuran for 5h; Reflux; Inert atmosphere;
55.1%
4-bromo-9H-fluorene-9-one
4269-17-4

4-bromo-9H-fluorene-9-one

4-N,N-diphenylamino-1-bromobenzene
36809-26-4

4-N,N-diphenylamino-1-bromobenzene

C31H22BrO2P

C31H22BrO2P

Conditions
ConditionsYield
Stage #1: 4-N,N-diphenylamino-1-bromobenzene With n-butyllithium In tetrahydrofuran at -78℃; for 1h; Inert atmosphere;
Stage #2: 4-bromo-9H-fluorene-9-one In tetrahydrofuran at 20℃; for 1h; Inert atmosphere;
50%

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