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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

(S)-(+)-2-METHYLGLUTARICACID

Cas:4286-15-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

(S)-(+)-2-Phenylbutyric acid

Cas:4286-15-1

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Food Grade CAS 4286-15-1 with high-quality service

Cas:4286-15-1

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

Benzeneacetic acid, a-ethyl-, (aS)-

Cas:4286-15-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

(S)-(+)-2-PHENYLBUTYRIC ACID CAS:4286-15-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organ

(S)-(+)-2-PHENYLBUTYRIC ACID CAS:4286-15-1

Cas:4286-15-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Benzeneacetic acid, a-ethyl-, (aS)-

Cas:4286-15-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Benzeneacetic acid, a-ethyl-, (aS)-

Cas:4286-15-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Benzeneacetic acid, a-ethyl-, (aS)-

Cas:4286-15-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

(S)-(+)-2-Phenylbutyric acid

Cas:4286-15-1

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providing h

Factory Supply S(+)-2-phenylbutyric acid

Cas:4286-15-1

Min.Order:0

Negotiable

Type:Other

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Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

Benzeneacetic acid, a-ethyl-, (aS)-

Cas:4286-15-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

(S)-(+)-2-PHENYLBUTYRIC ACID

Cas:4286-15-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Benzeneacetic acid, a-ethyl-, (aS)-

Cas:4286-15-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

DB BIOTECH CO., LTD

best seller Application:API

(S)-(+)-2-PHENYLBUTYRIC ACID

Cas:4286-15-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

(S)-(+)-2-PHENYLBUTYRIC ACIDCASAppearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

(S)-(+)-2-PHENYLBUTYRIC ACIDCAS

Cas:4286-15-1

Min.Order:0

Negotiable

Type:Other

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Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

(S)-(+)-2-PHENYLBUTYRIC ACID

Cas:4286-15-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

4286-15-1

Cas:4286-15-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hebei Muhuang Technology Co., Ltd

best seller Application:API

(S)-(+)-2-PHENYLBUTYRIC ACID

Cas:4286-15-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

(S)-(+)-2-PHENYLBUTYRIC ACID

Cas:4286-15-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

LEAP CHEM Co., Ltd.

Best Seller, High Quality, Competitive Price, Fast Delivery, Quick ResponseAppearance:powder, or liquid Storage:Stored in room temperature, ventilated place Package:Bottle, barrel, cargo, container, etc. Application:Pharmaceuticals, intermediates, AP

(S)-(+)-2-PHENYLBUTYRIC ACID

Cas:4286-15-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Jilin haofei import and export trade Co.,Ltd

Price, service, company and transport advantage: 1. Best service, place of origin China, high quality, and reasonable price. 2. It's customers' right to choose the package (EMS, DHL, FEDEX, UPS). 3. It's customers' right

(S)-(+)-2-METHYLGLUTARICACID CAS NO.4286-15-1

Cas:4286-15-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Chemical Technology Co.,LTD

1. Production capacity: we have three production base with high-tech production equipment and instruments, equipped with professional production personnel, meet your requirements.2. Quality assurance: we have a first-class testing equipment and testi

(S)-(+)-2-PHENYLBUTYRIC ACID

Cas:4286-15-1

Min.Order:0

Negotiable

Type:Other

inquiry

HuBei Ipure Biotech CO.,ltd

HuBei ipure is a diversified product production and operation enterprise, with API, pharma intermediates, and other fine chemicals as well as R&D and pigments development and sales as one of the large enterprises, with more than 130 acres of pl

(S)-(+)-2-Phenylbutyric acid

Cas:4286-15-1

Min.Order:1 Gram

FOB Price: $1.0 / 2.0

Type:Trading Company

inquiry

Shanghai Hanhong Scientific Co.,Ltd.

factory,reasonable price Appearance:detailed see specifications Storage:Store in dry, dark and ventilated place. Package:according to the clients requirement Application:pharmaceutical intermediates Transportation:by courier,air or sea Port:S

(S)-2-Phenylbutanoic acid4286-15-1

Cas:4286-15-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Share Chemical Co., Ltd

At Share Chemical Company, we scrupulously abide by our policy of “Excellent Quality at a Reasonable Price”. We strive to satisfy all of our customers by providing the finest quality products supported by the finest in customer servi

(S)-(+)-2-Phenylbutyric acid

Cas:4286-15-1

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Capot Chemical Co., Ltd.

At Capot,We can synthesize and purify your complex molecules from 100 gram to 10 tons.Appearance:Clear colorless to light yellow liquid Storage:Dry,Seal and Cool place Package:1G,5G,10G,25G,100G,250G,500G,1KG,5KG,10KG,25KG,50KG,100KG,150KG,200KG. App

(S)-(+)-2-Phenylbutyric acid

Cas:4286-15-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai united Scientific Co.,Ltd.

United Scientific Company Located in Shanghai of China , is a competitive player in the global specialty and fine chemical market. Fenghua has both the expertise and flexibility to produce a wide range of chemicals. Focusing on developing the innovat

Benzeneacetic acid, a-ethyl-, (aS)-

Cas:4286-15-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Finetech Industry Limited

FINETECH INDUSTRY LIMITED is a LONDON based CRO company providing drug discovery & development services to worldwide clients. FINETECH INDUSTRY LIMITED supplies the (S)-(+)-2-PHENYLBUTYRIC ACID, CAS:4286-15-1 with the most competitive price and the b

(S)-(+)-2-PHENYLBUTYRIC ACID

Cas:4286-15-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Nanjing Raymon Biotech Co., Ltd.

Benzeneacetic acid, a-ethyl-, (aS)- Storage:keep in dry and cool condition Package:25kg or according to cutomer's demand Application:Chemical research/pharma intermediate Transportation:By Sea,by Air,By courier like DHL or Fedx. Port:Shanghai/Shenzhe

Benzeneacetic acid, a-ethyl-, (aS)-

Cas:4286-15-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Skyrun Industrial Co.,Ltd

Adequate stocks available,prompt shipment,Strictly control on quality,Timely after-sales

(S)-(+)-2-Phenylbutyric acid, 99%

Cas:4286-15-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

(R)-1-(4-pyridinyl)ethanol
27854-88-2

(R)-1-(4-pyridinyl)ethanol

2-Phenylbutyric acid
90-27-7

2-Phenylbutyric acid

A

(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

B

(2R)-2-phenylbutanoic acid
938-79-4

(2R)-2-phenylbutanoic acid

C

2-Phenyl-butyric acid (R)-1-pyridin-4-yl-ethyl ester
88549-64-8, 88549-65-9, 88588-27-6, 88588-31-2, 97996-71-9, 134624-71-8

2-Phenyl-butyric acid (R)-1-pyridin-4-yl-ethyl ester

Conditions
ConditionsYield
With Palomo reagent; triethylamine In toluene for 48h; Ambient temperature; Yields of byproduct given;A n/a
B n/a
C 99%
With dicyclohexyl-carbodiimide In toluene for 6h; Product distribution; kinetic resolution of racemic carboxylic acids; other carboxylic acids and homochiral alcohols; var. reaction time, temperature and solvents;A n/a
B n/a
C 86%
With dicyclohexyl-carbodiimide In toluene for 6h; Yields of byproduct given;A n/a
B n/a
C 86%
(4R)-3-((2S)-2-phenylbutanoyl)-4-phenyl-oxazolidin-2-one

(4R)-3-((2S)-2-phenylbutanoyl)-4-phenyl-oxazolidin-2-one

A

(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

B

(4R)-phenyl-2-oxazolidinone
90319-52-1

(4R)-phenyl-2-oxazolidinone

Conditions
ConditionsYield
Stage #1: (4R)-3-((2S)-2-phenylbutanoyl)-4-phenyl-oxazolidin-2-one With lithium hydroxide monohydrate; dihydrogen peroxide In tetrahydrofuran; water at 20℃; for 12h; Inert atmosphere;
Stage #2: With hydrogenchloride In water pH=3; Inert atmosphere;
A 91%
B 82%
With dihydrogen peroxide; lithium hydroxide In tetrahydrofuran; waterA 89%
B 85%
1,1-bis(trimethylsilyloxy)-2-phenylbutene
167476-42-8

1,1-bis(trimethylsilyloxy)-2-phenylbutene

(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

Conditions
ConditionsYield
With methanol; 2,6-bis(1,3-dimethylphenanthren-9-yl)-4H-dinaphtho[2,1-d:1',2'-f][1,3,2]dithiazepine 3,3,5,5-tetraoxide In dichloromethane at 20℃; for 0.25h; Inert atmosphere; enantioselective reaction;82%
(S)-2-Phenyl-butyric acid 2,2-diphenyl-vinyl ester
865363-42-4

(S)-2-Phenyl-butyric acid 2,2-diphenyl-vinyl ester

(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

Conditions
ConditionsYield
With lithium hydroxide; dihydrogen peroxide In tetrahydrofuran; water at 0℃; for 1.5h;81%
phenylacetic acid
103-82-2

phenylacetic acid

ethyl iodide
75-03-6

ethyl iodide

(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

Conditions
ConditionsYield
Stage #1: phenylacetic acid With n-butyllithium; N1,N3-bis((R)-1-phenyl-2-(piperidin-1-yl)ethyl)propane-1,3-diamine In tetrahydrofuran; hexanes at 0℃; Inert atmosphere;
Stage #2: ethyl iodide In tetrahydrofuran; hexanes at -78℃; for 0.166667h; Inert atmosphere; optical yield given as %ee; enantioselective reaction;
81%
2-Phenylbutyric acid
90-27-7

2-Phenylbutyric acid

A

(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

B

(2R)-2-phenylbutanoic acid
938-79-4

(2R)-2-phenylbutanoic acid

Conditions
ConditionsYield
A 70%
B n/a
A n/a
B 70%
Stage #1: 2-Phenylbutyric acid With (1S,2R)-1-amino-2-indanol In ethanol; water at 30℃; for 12h; Addition;
Stage #2: With hydrogenchloride Hydrolysis;
(R)-(-)-2-phenylbutyramide
74042-63-0

(R)-(-)-2-phenylbutyramide

A

(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

B

(2R)-2-phenylbutanoic acid
938-79-4

(2R)-2-phenylbutanoic acid

Conditions
ConditionsYield
With hydrogen cation for 7h; Heating; Title compound not separated from byproducts;A n/a
B 54%
2-phenylbutyramide
90-26-6

2-phenylbutyramide

A

(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

B

(R)-(-)-2-phenylbutyramide
74042-63-0

(R)-(-)-2-phenylbutyramide

Conditions
ConditionsYield
With potassium phosphate buffer; Rhodococcus sp. AJ270 at 30℃; for 120h; pH=7.0; Hydrolysis;A 51%
B 47%
at 30℃; for 145h; Rhodococcus sp. (SP 361), pH 7;A 25%
B 20%
2-phenylbutanenitrile
769-68-6

2-phenylbutanenitrile

A

(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

B

(R)-(-)-2-phenylbutyramide
74042-63-0

(R)-(-)-2-phenylbutyramide

Conditions
ConditionsYield
With Rhodococcus sp. CGMCC 0497 In phosphate buffer for 34h; pH=7.0;A 38%
B 50%
With potassium phosphate buffer; Rhodococcus sp. AJ270 at 30℃; for 96h; pH=7.0; Hydrolysis;A 40%
B 34%
2-phenylbutanenitrile
769-68-6

2-phenylbutanenitrile

A

(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

B

(S)-2-phenylbutyramide
13490-76-1

(S)-2-phenylbutyramide

C

(R)-(-)-2-phenylbutyramide
74042-63-0

(R)-(-)-2-phenylbutyramide

Conditions
ConditionsYield
at 30℃; for 71h; Rhodococcus sp. (SP 361), pH 7;A 22%
B n/a
C 31%
at 30℃; for 71h; Rhodococcus sp. (SP 361), pH 7; Title compound not separated from byproducts;A 22%
B n/a
C 31%
for 71h; SP361 enzyme system; Yields of byproduct given;A 22%
B n/a
C n/a
for 71h; SP361 enzyme system; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
(S)-1-phenyl-ethylamine
2627-86-3

(S)-1-phenyl-ethylamine

2-Phenylbutyric acid
90-27-7

2-Phenylbutyric acid

(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

2-Phenylbutyric acid
90-27-7

2-Phenylbutyric acid

Cinchonidin
485-71-2

Cinchonidin

(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

(S)-2-Octanol
6169-06-8

(S)-2-Octanol

(R)-(-)-2-phenylbutyric acid chloride
105227-22-3

(R)-(-)-2-phenylbutyric acid chloride

A

(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

B

(2R)-2-phenylbutanoic acid
938-79-4

(2R)-2-phenylbutanoic acid

C

(S)-2-Phenyl-butyric acid (S)-1-methyl-heptyl ester
126415-96-1

(S)-2-Phenyl-butyric acid (S)-1-methyl-heptyl ester

D

(R)-2-Phenyl-butyric acid (S)-1-methyl-heptyl ester
53483-37-7, 53483-38-8, 126415-96-1

(R)-2-Phenyl-butyric acid (S)-1-methyl-heptyl ester

Conditions
ConditionsYield
dmap In pyridine at 60℃; for 4h; Product distribution; study of racemization of acid chloride;
2-phenylbutyramide
90-26-6

2-phenylbutyramide

A

(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

B

(2R)-2-phenylbutanoic acid
938-79-4

(2R)-2-phenylbutanoic acid

Conditions
ConditionsYield
for 216h; SP361 enzyme system; Yield given. Title compound not separated from byproducts;
(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

2-phenylbutyric anhydride
1519-21-7

2-phenylbutyric anhydride

A

(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

B

(S)-2-phenylbutyric acid-(R)-1-phenylethyl ester
53483-44-6, 53483-45-7, 84713-91-7

(S)-2-phenylbutyric acid-(R)-1-phenylethyl ester

C

(R)-2-phenylbutyric acid-(R)-1-phenylethyl ester
53483-44-6, 53483-45-7, 84713-91-7

(R)-2-phenylbutyric acid-(R)-1-phenylethyl ester

D

(2R)-2-phenylbutanoic acid
938-79-4

(2R)-2-phenylbutanoic acid

Conditions
ConditionsYield
In pyridine for 20h; Product distribution; Ambient temperature; reaction with further chiral secondary alcohols for determination of their absolute configuration;
2-Phenylbutyryl chloride
36854-57-6

2-Phenylbutyryl chloride

neomeranol
120637-78-7

neomeranol

A

(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

B

(2R)-2-phenylbutanoic acid
938-79-4

(2R)-2-phenylbutanoic acid

C

(R)-2-Phenyl-butyric acid (1R,2R,3R,5S,8R,9R)-9-bromo-1,4,4,8-tetramethyl-tricyclo[6.3.0.03,5]undec-2-yl ester
120637-80-1, 126456-60-8

(R)-2-Phenyl-butyric acid (1R,2R,3R,5S,8R,9R)-9-bromo-1,4,4,8-tetramethyl-tricyclo[6.3.0.03,5]undec-2-yl ester

D

(S)-2-Phenyl-butyric acid (1R,2R,3R,5S,8R,9R)-9-bromo-1,4,4,8-tetramethyl-tricyclo[6.3.0.03,5]undec-2-yl ester
120637-80-1, 126456-60-8

(S)-2-Phenyl-butyric acid (1R,2R,3R,5S,8R,9R)-9-bromo-1,4,4,8-tetramethyl-tricyclo[6.3.0.03,5]undec-2-yl ester

Conditions
ConditionsYield
dmap In pyridine at 60℃; for 4h; Product distribution; reaction with futher chiral alcohols for determination of their absolute configuration;
methyl 2-phenylbutanoate
2294-71-5

methyl 2-phenylbutanoate

A

(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

B

(2R)-2-phenylbutanoic acid
938-79-4

(2R)-2-phenylbutanoic acid

Conditions
ConditionsYield
With water asymmetric hydrolysis with Aspergillus sojae or bacteria; also for other (+/-)-α-substituted carboxylic acid esters;
methyl 2-phenylbutanoate
2294-71-5

methyl 2-phenylbutanoate

A

(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

B

(2R)-2-phenylbutanoic acid
938-79-4

(2R)-2-phenylbutanoic acid

C

(+)-(S)-methyl 2-phenylbutanoate
26164-15-8

(+)-(S)-methyl 2-phenylbutanoate

D

(-)-(R)-2-phenyl-butyric acid methyl ester
2294-71-5, 26164-15-8, 127641-43-4, 88424-45-7

(-)-(R)-2-phenyl-butyric acid methyl ester

Conditions
ConditionsYield
With sodium hydroxide In water for 2h; Ambient temperature; horse liver esterase, pH 7.2; Yield given. Yields of byproduct given;
Yield given. Yields of byproduct given;
2-phenylbutyric anhydride
1519-21-7

2-phenylbutyric anhydride

3,4-epoxy-14-hydroxy-7,18-dolabelladiene
76164-03-9, 76189-99-6

3,4-epoxy-14-hydroxy-7,18-dolabelladiene

(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

Conditions
ConditionsYield
Yield given. Multistep reaction;
2-phenylbutyric anhydride
1519-21-7

2-phenylbutyric anhydride

(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

2-phenylbutyric anhydride
1519-21-7

2-phenylbutyric anhydride

A

(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

B

(2R)-2-phenylbutanoic acid
938-79-4

(2R)-2-phenylbutanoic acid

Conditions
ConditionsYield
With (R)-1-phenylethanol In pyridine for 20h; Ambient temperature; optical yield: 74.5percent; Yield given;
With (-)-8α-methyl-trans-1β-decalol; water Product distribution; multistep reaction: 1.) pyridine, room temperature, overnight, 2.) room temperature, 2 h; other secondary alcohols; kinetic resolution;
((1S,4aR,8aR)-4a,6-Dimethyl-1,2,3,4,4a,5,8,8a-octahydro-naphthalen-1-yl)-(1-phenyl-ethyl)-amine
77495-35-3

((1S,4aR,8aR)-4a,6-Dimethyl-1,2,3,4,4a,5,8,8a-octahydro-naphthalen-1-yl)-(1-phenyl-ethyl)-amine

(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal 2.) Horeau's method; Multistep reaction;
((1S,4aS,8aS)-4a,6-Dimethyl-1,2,3,4,4a,5,8,8a-octahydro-naphthalen-1-yl)-(1-phenyl-ethyl)-amine
77495-33-1

((1S,4aS,8aS)-4a,6-Dimethyl-1,2,3,4,4a,5,8,8a-octahydro-naphthalen-1-yl)-(1-phenyl-ethyl)-amine

(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal 2.) Horeau's method; Multistep reaction;
2-Phenylbutyric acid
90-27-7

2-Phenylbutyric acid

(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

Conditions
ConditionsYield
43.0 g
2-Phenylbutyric acid
90-27-7

2-Phenylbutyric acid

A

(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

B

(2R)-2-phenylbutanoic acid
938-79-4

(2R)-2-phenylbutanoic acid

C

2-Phenyl-butyric acid (R)-1-pyridin-4-yl-ethyl ester
88549-64-8, 88549-65-9, 88588-27-6, 88588-31-2, 97996-71-9, 134624-71-8

2-Phenyl-butyric acid (R)-1-pyridin-4-yl-ethyl ester

Conditions
ConditionsYield
Yield given. Yields of byproduct given. Title compound not separated from byproducts;
(1R,4S)-1,4-diphenyl-1-methoxymethoxypentan-2-one
124312-33-0

(1R,4S)-1,4-diphenyl-1-methoxymethoxypentan-2-one

(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

Conditions
ConditionsYield
With sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid In dichloromethane Ambient temperature;
(S)-N-((1S,2S)-2-Hydroxy-1-methyl-2-phenyl-ethyl)-N-methyl-2-phenyl-butyramide
159345-11-6

(S)-N-((1S,2S)-2-Hydroxy-1-methyl-2-phenyl-ethyl)-N-methyl-2-phenyl-butyramide

A

(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

B

(2R)-2-phenylbutanoic acid
938-79-4

(2R)-2-phenylbutanoic acid

Conditions
ConditionsYield
With sulfuric acid In 1,4-dioxane Heating; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
With sulfuric acid In 1,4-dioxane for 1.5h; Heating; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
(+)-(S)-methyl 2-phenylbutanoate
26164-15-8

(+)-(S)-methyl 2-phenylbutanoate

(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

Conditions
ConditionsYield
With potassium hydroxide In ethanol Yield given;
phenylacetic acid
103-82-2

phenylacetic acid

ethyl iodide
75-03-6

ethyl iodide

A

(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

B

(2R)-2-phenylbutanoic acid
938-79-4

(2R)-2-phenylbutanoic acid

Conditions
ConditionsYield
With n-butyllithium; (2,2-Me2-propyl)-((R)-1-phenyl-2-piperidin-1-yl-ethyl)-amine 1.) hexane, THF, 0 deg C, 15 min, 2.) hexane, THF, -78 deg C, 20 min; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

(S)-2-phenylbutan-1-ol
33442-47-6

(S)-2-phenylbutan-1-ol

Conditions
ConditionsYield
Stage #1: (S)-2-phenylbutyric acid With sodium tetrahydroborate In tetrahydrofuran at 0℃;
Stage #2: With iodine In tetrahydrofuran at 0 - 20℃;
100%
Stage #1: (S)-2-phenylbutyric acid With sodium tetrahydroborate; iodine In tetrahydrofuran at 0 - 20℃;
Stage #2: With hydrogenchloride In tetrahydrofuran; water
100%
Stage #1: (S)-2-phenylbutyric acid With sodium tetrahydroborate In tetrahydrofuran at 0℃;
Stage #2: With iodine In tetrahydrofuran at 0 - 20℃;
Stage #3: With hydrogenchloride; water In tetrahydrofuran
100%
(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

(S)-(+)-2-phenylbutyric acid chloride
40473-35-6

(S)-(+)-2-phenylbutyric acid chloride

Conditions
ConditionsYield
With thionyl chloride for 1h; Heating;100%
With thionyl chloride In dichloromethane for 4h; Heating;80%
With thionyl chloride at 0 - 70℃; for 0.5h; Chlorination;
With oxalyl dichloride for 2h;
With thionyl chloride for 3h; Reflux;
(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

methyllithium
917-54-4

methyllithium

(S)-3-phenyl-2-pentanone
105183-84-4

(S)-3-phenyl-2-pentanone

Conditions
ConditionsYield
Stage #1: methyllithium With copper(l) cyanide In diethyl ether at 0℃; for 0.0833333h; Inert atmosphere;
Stage #2: (S)-2-phenylbutyric acid In diethyl ether at 0 - 20℃; for 15h; Inert atmosphere;
99%
(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

methyl (2R)-2-amino-2-[4-(2-methylpentyloxy)phenyl]acetate hydrochloride

methyl (2R)-2-amino-2-[4-(2-methylpentyloxy)phenyl]acetate hydrochloride

methyl (2R)-2-[4-(2-methylpentyloxy)phenyl]-2-[(S)-2-phenylbutanamido]acetate

methyl (2R)-2-[4-(2-methylpentyloxy)phenyl]-2-[(S)-2-phenylbutanamido]acetate

Conditions
ConditionsYield
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine In acetonitrile at 20℃; for 5h; Inert atmosphere;95%
(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

1-phenyl-propan-1-one
93-55-0

1-phenyl-propan-1-one

Conditions
ConditionsYield
With 1H-imidazole; sodium periodate In water; acetonitrile at 20℃; for 75h;92%
(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

(S)-2-phenyl-butyronitrile
56652-56-3

(S)-2-phenyl-butyronitrile

Conditions
ConditionsYield
With ammonium carbonate; diphosphorus tetraiodide In carbon disulfide at 20℃; for 7h;90%
With sodium azide; triethylamine; triphenylphosphine; (bis-(2-methoxyethyl)amino)sulfur trufluoride In dichloromethane; dimethyl sulfoxide at 0 - 20℃; for 0.5h;85%
n-butyllithium
109-72-8, 29786-93-4

n-butyllithium

(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

(S)-3-phenyl-4-octanone
1333149-06-6

(S)-3-phenyl-4-octanone

Conditions
ConditionsYield
Stage #1: n-butyllithium With copper(l) cyanide In diethyl ether; hexane at 0℃; for 0.0833333h; Inert atmosphere;
Stage #2: (S)-2-phenylbutyric acid In diethyl ether; hexane at 0 - 20℃; for 15h; Inert atmosphere;
90%
lithium dibutylcyanocuprate
80473-69-4

lithium dibutylcyanocuprate

(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

A

(S)-3-phenyl-4-octanone
1333149-06-6

(S)-3-phenyl-4-octanone

B

C18H30O
1333149-07-7

C18H30O

Conditions
ConditionsYield
In diethyl ether at 0 - 20℃; for 15h; Inert atmosphere; optical yield given as %ee;A 90%
B 6%
(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

(S,S)-α-Phenylbutyric anhydride
16906-38-0

(S,S)-α-Phenylbutyric anhydride

Conditions
ConditionsYield
With dicyclohexyl-carbodiimide In dichloromethane at 20℃; stereospecific reaction;85%
(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

N,0-dimethylhydroxylamine
1117-97-1

N,0-dimethylhydroxylamine

(2S)-N-ethoxy-N-methyl-2-phenylbutanamide
130250-64-5

(2S)-N-ethoxy-N-methyl-2-phenylbutanamide

Conditions
ConditionsYield
Stage #1: (S)-2-phenylbutyric acid With N-ethyl-N,N-diisopropylamine; (bis-(2-methoxyethyl)amino)sulfur trufluoride In N,N-dimethyl-formamide at 0℃; for 0.25h;
Stage #2: N,0-dimethylhydroxylamine In N,N-dimethyl-formamide at 0 - 20℃; for 4h; Further stages.;
83%
at 0 - 20℃; for 4.25h;
(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

(S)-2-phenylbutyramide
13490-76-1

(S)-2-phenylbutyramide

Conditions
ConditionsYield
With ammonia; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In water; N,N-dimethyl-formamide at 0 - 20℃; for 12h;80%
Multi-step reaction with 2 steps
1: oxalyl dichloride / 2 h
2: ammonium hydroxide; water / benzene
View Scheme
(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

N,O-dimethylhydroxylamine*hydrochloride
6638-79-5

N,O-dimethylhydroxylamine*hydrochloride

(2S)-N-ethoxy-N-methyl-2-phenylbutanamide
130250-64-5

(2S)-N-ethoxy-N-methyl-2-phenylbutanamide

Conditions
ConditionsYield
With pyridine; carbon tetrabromide; triphenylphosphine In dichloromethane for 0.166667h; Ambient temperature;71%
(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

(3S)-3-benzylmorpholine
77897-23-5

(3S)-3-benzylmorpholine

(S)-1-((S)-3-benzylmorpholino)-2-phenylbutan-1-one
1643770-64-2

(S)-1-((S)-3-benzylmorpholino)-2-phenylbutan-1-one

Conditions
ConditionsYield
Stage #1: (S)-2-phenylbutyric acid With diisopropyl-carbodiimide In tetrahydrofuran at 0℃; for 0.166667h; Inert atmosphere;
Stage #2: (3S)-3-benzylmorpholine In tetrahydrofuran at 20℃; Inert atmosphere;
68%
(3R)-3-benzylmorpholine
481038-59-9

(3R)-3-benzylmorpholine

(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

(2S)-1-((3R)-3-benzylmorpholino)-2-phenylbutan-1-one
1643770-70-0

(2S)-1-((3R)-3-benzylmorpholino)-2-phenylbutan-1-one

Conditions
ConditionsYield
Stage #1: (S)-2-phenylbutyric acid With diisopropyl-carbodiimide In tetrahydrofuran at 0℃; for 0.166667h; Inert atmosphere;
Stage #2: (3R)-3-benzylmorpholine In tetrahydrofuran at 20℃; Inert atmosphere;
68%
(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

Acetic acid (2S,3R,4R)-2-hydroxy-8-methoxy-3-methyl-1,7,12-trioxo-1,2,3,4,7,12-hexahydro-benzo[a]anthracen-4-yl ester

Acetic acid (2S,3R,4R)-2-hydroxy-8-methoxy-3-methyl-1,7,12-trioxo-1,2,3,4,7,12-hexahydro-benzo[a]anthracen-4-yl ester

4-O-acetyl-2-O-[(S)-2'-phenylbutyryl]rubiginone D2

4-O-acetyl-2-O-[(S)-2'-phenylbutyryl]rubiginone D2

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 21℃; for 2h; Esterification; Helmchen's method;65%
(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

3-hydroxy-2,2-dimethyl-1-(2-phenylacetyl)imidazolidin-4-one
1643771-07-6

3-hydroxy-2,2-dimethyl-1-(2-phenylacetyl)imidazolidin-4-one

(S)-2,2-dimethyl-5-oxo-3-(2-phenylacetyl)imidazolidin-1-yl 2-ethyl-2-phenylacetate
1643770-98-2

(S)-2,2-dimethyl-5-oxo-3-(2-phenylacetyl)imidazolidin-1-yl 2-ethyl-2-phenylacetate

Conditions
ConditionsYield
Stage #1: (S)-2-phenylbutyric acid With diisopropyl-carbodiimide In tetrahydrofuran at 0℃; for 0.333333h; Inert atmosphere;
Stage #2: 3-hydroxy-2,2-dimethyl-1-(2-phenylacetyl)imidazolidin-4-one In tetrahydrofuran at 20℃; Inert atmosphere;
65%
(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

silver(l) oxide
20667-12-3

silver(l) oxide

C10H11O2(1-)*Ag(1+)

C10H11O2(1-)*Ag(1+)

Conditions
ConditionsYield
In acetonitrile for 24h; Inert atmosphere; Darkness;64%
(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

N-benzyl-2,3-dihydroxypropionamide
117471-01-9

N-benzyl-2,3-dihydroxypropionamide

N-benzyl 2-hydroxy-3-(2-(S)-phenylbutyryloxy)propionamide

N-benzyl 2-hydroxy-3-(2-(S)-phenylbutyryloxy)propionamide

Conditions
ConditionsYield
With 1,1'-carbonyldiimidazole In tetrahydrofuran for 3h; Esterification; Heating;54%
(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

(S)-2-phenylbutyro hydroxamic acid
1201890-90-5

(S)-2-phenylbutyro hydroxamic acid

Conditions
ConditionsYield
With 4-methyl-morpholine; dmap; hydroxylamine hydrochloride; isocyanuric acid In dichloromethane at 0 - 20℃;51%
(S)-2-phenylbutyric acid
4286-15-1

(S)-2-phenylbutyric acid

N-((1R,2S,6R)-2-Hydroxy-6-hydroxymethyl-5-oxo-7-oxa-bicyclo[4.1.0]hept-3-en-3-yl)-acetamide

N-((1R,2S,6R)-2-Hydroxy-6-hydroxymethyl-5-oxo-7-oxa-bicyclo[4.1.0]hept-3-en-3-yl)-acetamide

(S)-2-Phenyl-butyric acid (1R,5S,6R)-4-acetylamino-5-hydroxy-2-oxo-7-oxa-bicyclo[4.1.0]hept-3-en-1-ylmethyl ester

(S)-2-Phenyl-butyric acid (1R,5S,6R)-4-acetylamino-5-hydroxy-2-oxo-7-oxa-bicyclo[4.1.0]hept-3-en-1-ylmethyl ester

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 2h;49%

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