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Ality Chemical Corporation

Astaxanthin 98% 10% 5% 1% CAS Number: 472-61-7 Specification: USP/BP/EP/FCC Certification: GMP/DMF/HACCP/HALAL/KOSHER Expiry Time: 2 Years Packing: 1kg/Tin, 5kg/Tin, 20kg/Drum, 25kg/Drum, 50kg/Drum, 200kg/Drum, 1MT/Drum Storage: Store i

Factory Supply Astaxanthin

Cas:472-61-7

Min.Order:1 Gram

Negotiable

Type:Other

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Kono Chem Co.,Ltd

Superiority Kono Chem is a leading manufacturer and supplier of chemicals in China. We develop ,produce and distribute high quality pharmaceuticals, intermediates, special chemicals and other fine chemicals. We could give you: 1.Best quality

Astaxanthin

Cas:472-61-7

Min.Order:1 Kilogram

FOB Price: $150.0 / 1000.0

Type:Other

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Vertexyn (Nanjing) Bioworks Co., Ltd.

1. Rich in Natural Astaxanthin: Astaxanthin is a potent antioxidant, approximately 6,000 times stronger than vitamin C. It quickly enhances the vitality of shrimp and crabs, with noticeable effects in 1-2 days. 2. Neutralizes Harmful Free Radicals:

Natural Material Manufacturer Directly Offer Astaxanthin with Top Quality & Best Price

Cas:472-61-7

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Binbo Biological Co., Ltd

1.high purity 2.consistent quality 3.competitive price 4.fast shipping Binbo Biological Products Co. Ltd., is a professional high-tech enterprise which engaged in Biological products and raw materials. Binbo is engaged in R&D with perfect eq

High quality Astaxanthin powder

Cas:472-61-7

Min.Order:1 Kilogram

FOB Price: $100.0 / 200.0

Type:Lab/Research institutions

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Hangzhou Think Chemical Co. Ltd

HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about ten years of business experiences on the marketing & distribution, thinkchem specializes in exp

Astaxanthin

Cas:472-61-7

Min.Order:1 Kilogram

Negotiable

Type:Other

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Greenutra Resource Inc

Astaxanthin Powder Specification: Name: Astaxanthin Powder Assay: 1%--8% Identification Standardization Aspect

Astaxanthin Powder

Cas:472-61-7

Min.Order:1 Kilogram

FOB Price: $30.0

Type:Trading Company

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Xi'an Quanao Biotech Co., Ltd.

Pure Haematococcus Pluvialis Extract Powder Astaxanthin 10% Feed Grade Astaxanthin Professional Factory We has a complete production and operating system, with an annual output capacity of 2000 tons. It can produce variety of content and proportion

Pure Haematococcus Pluvialis Extract Powder Astaxanthin 10% Feed Grade Astaxanthin

Cas:472-61-7

Min.Order:1 Kilogram

FOB Price: $105.0 / 257.0

Type:Manufacturers

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

1.Free sample(10-20g or enough to detection) and Unconditional assume respons 2.100% Natural porduct, without any synthetize ingredient 3.Manufacturer direct supply, provide OEM, R&D service 4.ISO/HACCP/KOSHER/GMP/FDA 5.Leading plant ex

CAS No. 472-61-7 Astaxanthin

Cas:472-61-7

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

ShangHai Soyoung Biotechnology Inc

Trade Assurance Get full protection for your orders 100% Product quality protection 100% On-time shipment protection 100% Payment protection Appearance:red powder Storage:Store in a cool dry place, avoiding sunlight directly Package:aluminium foil

Haematococcus Pluvialis Extract Astaxanthin Powder

Cas:472-61-7

Min.Order:1 Kilogram

FOB Price: $188.0

Type:Lab/Research institutions

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Astaxanthin Manufacturer/High quality/Best price/In stock

Cas:472-61-7

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Sinoway Industrial Co., Ltd.

Sinoway Industrial co., ltd. was established in 1987 in Xiamen, China, and now has been a leading group specialized in research, development, custom manufacturing and trading of pharmaceutical intermediates, APIs, health and food supplements, cosmeti

Haematococcus Pluvialis Extract Astaxanthin powder

Cas:472-61-7

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Astaxanthin supplier in China

Cas:472-61-7

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Hebei yanxi chemical co.,LTD.

Hebei yanxi chemical co., LTD is a professional research, development and production 2-phenylacetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low carbon environ

Astaxanthin CAS NO.472-61-7

Cas:472-61-7

Min.Order:100 Gram

FOB Price: $2.0

Type:Manufacturers

inquiry

Wuhan Fortuna Chemical Co.,Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; ...... Appearance:Dark red powder Storage:-20°C Package:1kg/foil bag; 25kg/fibe

Good quality Natural astaxanthin powder 4% CAS 472-61-7 extracted from haematococcus pluvialis

Cas:472-61-7

Min.Order:1 Kilogram

FOB Price: $170.0 / 250.0

Type:Trading Company

inquiry

Hefei TNJ chemical industry co.,ltd

TNJ is a chemical company since 2001. Our specialization, your Confidence ! We keep committing to meet the needs of both market and customers with our innovative technology, high stable quality products and excellent service. We always combine econ

astaxanthin oil 5%-10%(HPLC)

Cas:472-61-7

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Assay 98%min ----------------------------------------------------------------------------------------------

High purity astaxanthin CAS:472-61-7

Cas:472-61-7

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Manufacturers

inquiry

Baoding Faithful Industry Co., Ltd.

Sales: 1.24hours to reply your E-mail 2.Market information trend share with customers Suggestion for purchase decision Reputation: 1.Implementing contract terms strictly 2.Timely solve any discrepancy or goods claims Take our responsibility for loss

Cosmetic Grade Astaxanthin 2% Raw Material Astaxanthin

Cas:472-61-7

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality Food Grade Astaxanthin 472-61-7 HACCP Manufacturer

Cas:472-61-7

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Xian Changyue Biological Technology Co., Ltd.

Our Advantages: 1. Free samples and unconditional hypothetical responses. 2.100% natural product, without any synthetic ingredients. 3. Direct sales from manufacturers, providing OEM and R&D services. 4. Complete certificates. 5. China's lead

Astaxanthin

Cas:472-61-7

Min.Order:25 Kilogram

Negotiable

Type:Manufacturers

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

Astaxanthin

Cas:472-61-7

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

inquiry

Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality Astaxanthin

Cas:472-61-7

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

Astaxanthin Powder

Cas:472-61-7

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Product Name: Astaxanthin Synonyms: 3,3'-DIHYDROXY-B,B-CAROTENE-4,4'-DIONE;3,3-DIHYDROXY-B,B-CAROTENE-4,4-DIONE;3,3'-DIHYDROXY-BETA,BETA-CAROTENE-4,4'-DIONE;ASTAXANTHIN;AXN;Astazine 5%;(3S,3’S)-3,3’-Dihydroxy-.beta.,.be

472-61-7 Astaxanthin

Cas:472-61-7

Min.Order:1 Kilogram

FOB Price: $500.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

Haematococcus Pluvialis Powder Astaxanthin:472-61-7

Cas:472-61-7

Min.Order:1 Kilogram

FOB Price: $10.0 / 16.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Food Grade CAS 472-61-7 with best price

Cas:472-61-7

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Assay by HPLC Natural : 2% 2.5% 3%by HPLC 2% 2.5% 3% by UV Synthetic: 2% 2.5% 3% 3.5% 4% 5% by HPLC 2% 2.5% 3% 3.5% 4% 5% by UV Astaxanthin Oil: 5% 8% 10% by HPLC 5% 8% 10% b

3,3'-Dihydroxy-beta,beta-carotene-4,4'-dione

Cas:472-61-7

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Appearance:Drak-purple Storage:ln stock Package:25kg/Barrel Application:Enhance immunity, anti-oxidation, anti-inflammatory Transportation:Express/Sea/Air Port:Any port of china

China supplier Astanxanthin

Cas:472-61-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:dark red powder Storage:Store in sealed containers at cool &

HANWAYS CHEMPHARM CO.,LIMITED

Hanways chempharm is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. The marketing department is located in Wuhan. We have two GMP facilities in Hubei Pr

China Products/Suppliers Natural Haematococcus Pluvialis Extract Astaxanthin Oil Astaxanthin Powder

Cas:472-61-7

Min.Order:1 Kilogram

FOB Price: $200.0 / 400.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1,In No Less five years exporting experience. 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Onchem specialized in APIs, chemical intermediate

Topsale Astaxanthin99% with lower price

Cas:472-61-7

Min.Order:25 Kilogram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Synthetic route

(2E,4E,6E)-2,7-dimethyl-2,4,6-octatrienedial
5056-17-7

(2E,4E,6E)-2,7-dimethyl-2,4,6-octatrienedial

<5-((S)-4-Hydroxy-2,6,6-trimethyl-3-oxo-1-cyclohexen-1-yl)-3-methyl-2,4-pentadienyl>triphenylphosphoniumbromid

<5-((S)-4-Hydroxy-2,6,6-trimethyl-3-oxo-1-cyclohexen-1-yl)-3-methyl-2,4-pentadienyl>triphenylphosphoniumbromid

A

(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

B

(3R,3'S)-3,3′-dihydroxy-β,β′-caroten-4,4′-dione
71772-51-5

(3R,3'S)-3,3′-dihydroxy-β,β′-caroten-4,4′-dione

Conditions
ConditionsYield
With sodium methylate In methanol at 0 - 25℃; for 4h;A 94.6%
B 4.2 % Chromat.
In various solvent(s) for 20h; Heating;A 97.7 % Chromat.
B 2.1 % Chromat.
C12H20O4
696647-73-1

C12H20O4

[(4E)-5-(4-hydroxy-2,6,6-trimethyl-3-oxo-1-cyclohexen-1-yl)-3-methyl-2,4-pentadienyl]-triphenylphosphonium bromide

[(4E)-5-(4-hydroxy-2,6,6-trimethyl-3-oxo-1-cyclohexen-1-yl)-3-methyl-2,4-pentadienyl]-triphenylphosphonium bromide

(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

Conditions
ConditionsYield
Stage #1: C12H20O4; [(4E)-5-(4-hydroxy-2,6,6-trimethyl-3-oxo-1-cyclohexen-1-yl)-3-methyl-2,4-pentadienyl]-triphenylphosphonium bromide With sodium methylate In methanol at 0℃; for 2h; Wittig Reaction;
Stage #2: With acetic acid In methanol; water at 20 - 75℃; for 20h; Heating / reflux;
83%
(3S,3'S)-Astaxanthin-di-(-)-camphanat

(3S,3'S)-Astaxanthin-di-(-)-camphanat

(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

Conditions
ConditionsYield
With sodium hydroxide In methanol; dichloromethane for 1.16667h; Ambient temperature;73%
(2E,4E,6E)-2,7-dimethyl-2,4,6-octatrienedial
5056-17-7

(2E,4E,6E)-2,7-dimethyl-2,4,6-octatrienedial

<5-((S)-4-Hydroxy-2,6,6-trimethyl-3-oxo-1-cyclohexen-1-yl)-3-methyl-2,4-pentadienyl>triphenylphosphoniumbromid

<5-((S)-4-Hydroxy-2,6,6-trimethyl-3-oxo-1-cyclohexen-1-yl)-3-methyl-2,4-pentadienyl>triphenylphosphoniumbromid

(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

Conditions
ConditionsYield
70.7%
(2E,4E,6E)-2,7-dimethyl-2,4,6-octatrienedial
5056-17-7

(2E,4E,6E)-2,7-dimethyl-2,4,6-octatrienedial

[(2E,4E)-3-Methyl-5-((S)-2,6,6-trimethyl-3-oxo-4-phenoxymethoxycarbonyl-cyclohex-1-enyl)-penta-2,4-dienyl]-triphenyl-phosphonium; bromide

[(2E,4E)-3-Methyl-5-((S)-2,6,6-trimethyl-3-oxo-4-phenoxymethoxycarbonyl-cyclohex-1-enyl)-penta-2,4-dienyl]-triphenyl-phosphonium; bromide

(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

Conditions
ConditionsYield
With sodium hydride In dichloromethane; isopropyl alcohol
(3S,3'S)-astaxanthin disulfate

(3S,3'S)-astaxanthin disulfate

(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

Conditions
ConditionsYield
With hydrogenchloride In methanol at 40℃;
3,4,3',4'-tetrahydroxy-β,β-carotene
6094-35-5, 28082-20-4

3,4,3',4'-tetrahydroxy-β,β-carotene

(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

Conditions
ConditionsYield
With 2,3-dicyano-5,6-dichloro-p-benzoquinone In 1,4-dioxane
(S)-6-Hydroxy-3-(5-hydroxy-3-methyl-1,3-pentadienyl)-2,4,4-trimethyl-2-cyclohexen-1-on

(S)-6-Hydroxy-3-(5-hydroxy-3-methyl-1,3-pentadienyl)-2,4,4-trimethyl-2-cyclohexen-1-on

(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: aq. HBr / CH2Cl2 / 0.17 h / 0 °C
3: 94.6 percent / NaOMe / methanol / 4 h / 0 - 25 °C
View Scheme
(S)-3-((1E,3E)-5-Bromo-3-methyl-penta-1,3-dienyl)-6-hydroxy-2,4,4-trimethyl-cyclohex-2-enone

(S)-3-((1E,3E)-5-Bromo-3-methyl-penta-1,3-dienyl)-6-hydroxy-2,4,4-trimethyl-cyclohex-2-enone

(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
2: 94.6 percent / NaOMe / methanol / 4 h / 0 - 25 °C
View Scheme
3,3'-dihydroxy-β,β-carotene-4,4'-dione
7542-45-2

3,3'-dihydroxy-β,β-carotene-4,4'-dione

A

(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

B

(3R,3'R)-3,3′-dihydroxy-β,β′-caroten-4,4′-dione
60760-95-4

(3R,3'R)-3,3′-dihydroxy-β,β′-caroten-4,4′-dione

C

(3R,3'S)-3,3′-dihydroxy-β,β′-caroten-4,4′-dione
71772-51-5

(3R,3'S)-3,3′-dihydroxy-β,β′-caroten-4,4′-dione

Conditions
ConditionsYield
Resolution of racemate;
(S)-2,7,11-trimethyl-13-(4-hydroxy-2,6,6-trimethyl-3-oxo-1-cyclohexen-1-yl)-2,4,6,8,10,12-tridecahexaen-1-al
72523-68-3

(S)-2,7,11-trimethyl-13-(4-hydroxy-2,6,6-trimethyl-3-oxo-1-cyclohexen-1-yl)-2,4,6,8,10,12-tridecahexaen-1-al

(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

Conditions
ConditionsYield
In ethanol for 3h; Heating / reflux;
astaxanthin radical-cation

astaxanthin radical-cation

(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

Conditions
ConditionsYield
With daidzein dianion In methanol; chloroform at 25℃; Thermodynamic data; Kinetics; Reagent/catalyst;
(4S)-4-acetoxy-3-oxo-1-(3-oxo-1-butenyl)-2,6,6-trimethyl-1-cyclohexene

(4S)-4-acetoxy-3-oxo-1-(3-oxo-1-butenyl)-2,6,6-trimethyl-1-cyclohexene

(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: E-2 / aq. phosphate buffer; acetone / 1 h / 20 - 30 °C / pH 7 / Large scale; Enzymatic reaction
2.1: pyridinium p-toluenesulfonate / toluene / 0.5 h / -5 - 5 °C / Large scale
3.1: tetrahydrofuran / 2 h / -75 - -55 °C / Large scale
4.1: hydrogen bromide / dichloromethane / 0.5 h / -21 - -11 °C / Large scale
5.1: triphenylphosphine; ethyloxirane / ethyl acetate / 24 h / 0 - 30 °C / Large scale
5.2: 30 h / Reflux; Inert atmosphere; Large scale
View Scheme
(4S)-4-hydroxy-3-oxo-1-(3-oxo-1-butenyl)-2,6,6-trimethyl-1-cyclohexene

(4S)-4-hydroxy-3-oxo-1-(3-oxo-1-butenyl)-2,6,6-trimethyl-1-cyclohexene

(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: pyridinium p-toluenesulfonate / toluene / 0.5 h / -5 - 5 °C / Large scale
2.1: tetrahydrofuran / 2 h / -75 - -55 °C / Large scale
3.1: hydrogen bromide / dichloromethane / 0.5 h / -21 - -11 °C / Large scale
4.1: triphenylphosphine; ethyloxirane / ethyl acetate / 24 h / 0 - 30 °C / Large scale
4.2: 30 h / Reflux; Inert atmosphere; Large scale
View Scheme
(4S)-4-(2-methoxypropan-2-yloxy)-3-oxo-1-(3-oxo-1-butenyl)-2,6,6-trimethyl-1-cyclohexene

(4S)-4-(2-methoxypropan-2-yloxy)-3-oxo-1-(3-oxo-1-butenyl)-2,6,6-trimethyl-1-cyclohexene

(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: tetrahydrofuran / 2 h / -75 - -55 °C / Large scale
2.1: hydrogen bromide / dichloromethane / 0.5 h / -21 - -11 °C / Large scale
3.1: triphenylphosphine; ethyloxirane / ethyl acetate / 24 h / 0 - 30 °C / Large scale
3.2: 30 h / Reflux; Inert atmosphere; Large scale
View Scheme
1-(3-hydroxy-3-methyl-1,4-pentadienyl)-(4S)-4-(2-methoxypropan-2-yloxy)-3-oxo-2,6,6-trimethyl-1-cyclohexene

1-(3-hydroxy-3-methyl-1,4-pentadienyl)-(4S)-4-(2-methoxypropan-2-yloxy)-3-oxo-2,6,6-trimethyl-1-cyclohexene

(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: hydrogen bromide / dichloromethane / 0.5 h / -21 - -11 °C / Large scale
2.1: triphenylphosphine; ethyloxirane / ethyl acetate / 24 h / 0 - 30 °C / Large scale
2.2: 30 h / Reflux; Inert atmosphere; Large scale
View Scheme
(2E,4E,6E)-2,7-dimethyl-2,4,6-octatrienedial
5056-17-7

(2E,4E,6E)-2,7-dimethyl-2,4,6-octatrienedial

1-(5-bromo-3-methyl-1,3-pentadienyl)-(4S)-4-hydroxy-3-oxo-2,6,6-trimethyl-1-cyclohexene

1-(5-bromo-3-methyl-1,3-pentadienyl)-(4S)-4-hydroxy-3-oxo-2,6,6-trimethyl-1-cyclohexene

(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

Conditions
ConditionsYield
Stage #1: 1-(5-bromo-3-methyl-1,3-pentadienyl)-(4S)-4-hydroxy-3-oxo-2,6,6-trimethyl-1-cyclohexene With ethyloxirane; triphenylphosphine In ethyl acetate at 0 - 30℃; for 24h; Large scale;
Stage #2: (2E,4E,6E)-2,7-dimethyl-2,4,6-octatrienedial With ethyloxirane; 2,6-di-tert-butyl-4-methyl-phenol In isopropyl alcohol for 30h; Reflux; Inert atmosphere; Large scale;
1.53 kg
2-[2-((4RS)-4-acetoxy-3-oxo-2,6,6-trimethyl-1-cyclohexenyl)vinyl]-2-methyl-1,3-dioxolane

2-[2-((4RS)-4-acetoxy-3-oxo-2,6,6-trimethyl-1-cyclohexenyl)vinyl]-2-methyl-1,3-dioxolane

(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1.1: LAY 400-AF / aq. phosphate buffer; toluene / 24 h / 37 °C / pH 7 / Enzymatic reaction
1.2: 3 h / 50 °C
2.1: hydrogenchloride / toluene; methanol; water / 2 h / 20 - 30 °C
3.1: E-2 / aq. phosphate buffer; acetone / 1 h / 20 - 30 °C / pH 7 / Large scale; Enzymatic reaction
4.1: pyridinium p-toluenesulfonate / toluene / 0.5 h / -5 - 5 °C / Large scale
5.1: tetrahydrofuran / 2 h / -75 - -55 °C / Large scale
6.1: hydrogen bromide / dichloromethane / 0.5 h / -21 - -11 °C / Large scale
7.1: triphenylphosphine; ethyloxirane / ethyl acetate / 24 h / 0 - 30 °C / Large scale
7.2: 30 h / Reflux; Inert atmosphere; Large scale
View Scheme
Multi-step reaction with 7 steps
1.1: LAY 400-AF / aq. phosphate buffer; toluene / 24 h / 37 °C / pH 7 / Enzymatic reaction
2.1: hydrogenchloride / toluene; methanol; water / 2 h / 20 - 30 °C
3.1: E-2 / aq. phosphate buffer; acetone / 1 h / 20 - 30 °C / pH 7 / Large scale; Enzymatic reaction
4.1: pyridinium p-toluenesulfonate / toluene / 0.5 h / -5 - 5 °C / Large scale
5.1: tetrahydrofuran / 2 h / -75 - -55 °C / Large scale
6.1: hydrogen bromide / dichloromethane / 0.5 h / -21 - -11 °C / Large scale
7.1: triphenylphosphine; ethyloxirane / ethyl acetate / 24 h / 0 - 30 °C / Large scale
7.2: 30 h / Reflux; Inert atmosphere; Large scale
View Scheme
2-[2-((4S)-4-acetoxy-3-oxo-2,6,6-trimethyl-1-cyclohexenyl)vinyl]-2-methyl-1,3-dioxolane

2-[2-((4S)-4-acetoxy-3-oxo-2,6,6-trimethyl-1-cyclohexenyl)vinyl]-2-methyl-1,3-dioxolane

(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: hydrogenchloride / toluene; methanol; water / 2 h / 20 - 30 °C
2.1: E-2 / aq. phosphate buffer; acetone / 1 h / 20 - 30 °C / pH 7 / Large scale; Enzymatic reaction
3.1: pyridinium p-toluenesulfonate / toluene / 0.5 h / -5 - 5 °C / Large scale
4.1: tetrahydrofuran / 2 h / -75 - -55 °C / Large scale
5.1: hydrogen bromide / dichloromethane / 0.5 h / -21 - -11 °C / Large scale
6.1: triphenylphosphine; ethyloxirane / ethyl acetate / 24 h / 0 - 30 °C / Large scale
6.2: 30 h / Reflux; Inert atmosphere; Large scale
View Scheme
canthaxanthin
514-78-3

canthaxanthin

(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

Conditions
ConditionsYield
Stage #1: canthaxanthin With iodosylbenzene; sodium hydroxide In methanol at 10 - 20℃; for 12.5h; Inert atmosphere;
Stage #2: With sulfuric acid In water at 20℃; for 5h; Reagent/catalyst; Temperature; Solvent;
4.48 g
(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

n-hexadecanoyl chloride
112-67-4

n-hexadecanoyl chloride

A

astaxanthin dipalmitate
5794-22-9

astaxanthin dipalmitate

B

(6S)-6-palmitoyloxy-3-[(all-E)-18-[(4S)-4-hydroxy-2,6,6-trimethyl-3-oxo-1-cyclohexenyl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-2,4,4-trimethyl-1-cyclohex-2-enone

(6S)-6-palmitoyloxy-3-[(all-E)-18-[(4S)-4-hydroxy-2,6,6-trimethyl-3-oxo-1-cyclohexenyl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-2,4,4-trimethyl-1-cyclohex-2-enone

Conditions
ConditionsYield
With pyridine In dichloromethane for 5h; Concentration;A 92.48%
B 0.63%
(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

C16H23ClO3Si

C16H23ClO3Si

astaxanthin diferulate

astaxanthin diferulate

Conditions
ConditionsYield
Stage #1: (3S,3'S)-astaxanthin; C16H23ClO3Si With pyridine In dichloromethane at 0 - 20℃; Inert atmosphere;
Stage #2: With caesium carbonate In water; N,N-dimethyl-formamide for 2h; Inert atmosphere;
80%
(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

Stearoyl chloride
112-76-5

Stearoyl chloride

astaxanthin dioctadecanoate
173422-82-7

astaxanthin dioctadecanoate

Conditions
ConditionsYield
With pyridine In dichloromethane at 20℃;80%
(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

n-hexadecanoyl chloride
112-67-4

n-hexadecanoyl chloride

astaxanthin dipalmitate
5794-22-9

astaxanthin dipalmitate

Conditions
ConditionsYield
With pyridine In dichloromethane at 20℃; Concentration; Reagent/catalyst; Temperature; Solvent;73%
With pyridine
n-dodecanoyl chloride
112-16-3

n-dodecanoyl chloride

(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

astaxanthin didodecanoate

astaxanthin didodecanoate

Conditions
ConditionsYield
With pyridine In dichloromethane at 20℃;73%
(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

n-decanoyl chloride
112-13-0

n-decanoyl chloride

[(1S)-4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4S)-4-decanoyloxy-2,6,6-trimethyl-3-oxocyclohexen-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethyl-2-oxocyclohex-3-en-1-yl] decanoate

[(1S)-4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4S)-4-decanoyloxy-2,6,6-trimethyl-3-oxocyclohexen-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethyl-2-oxocyclohex-3-en-1-yl] decanoate

Conditions
ConditionsYield
With pyridine In dichloromethane at 20℃;69%
(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

benzoic acid
65-85-0

benzoic acid

4,4'-dioxo-β,β-carotene-3,3'-diyl dibenzoate

4,4'-dioxo-β,β-carotene-3,3'-diyl dibenzoate

Conditions
ConditionsYield
With Novozyme 435 In methanol; toluene at 37℃; for 6h; Darkness; Enzymatic reaction;59%
(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

p-Toluic acid
99-94-5

p-Toluic acid

4,4'-dioxo-β,β-carotene-3,3'-diyl di(4-methylbenzoate)

4,4'-dioxo-β,β-carotene-3,3'-diyl di(4-methylbenzoate)

Conditions
ConditionsYield
With Novozyme 435 In methanol; toluene at 37℃; for 6h; Darkness; Enzymatic reaction;58%
nicotinic acid
59-67-6

nicotinic acid

(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

4,4'-dioxo-β,β-carotene-3,3'-diyl di(pyridine-3-carboxylate)

4,4'-dioxo-β,β-carotene-3,3'-diyl di(pyridine-3-carboxylate)

Conditions
ConditionsYield
With Novozyme 435 In methanol; toluene at 37℃; for 6h; Darkness; Enzymatic reaction;57%
(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

4-Nitrophenyl chloroformate
7693-46-1

4-Nitrophenyl chloroformate

C54H58N2O12

C54H58N2O12

Conditions
ConditionsYield
Stage #1: (3S,3'S)-astaxanthin With n-butyllithium In tetrahydrofuran at -70℃; for 0.25h;
Stage #2: 4-Nitrophenyl chloroformate In tetrahydrofuran at 20℃; for 8h;
56.1%
(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

4,4'-dioxo-β,β-carotene-3,3'-diyl di(2-hydroxy-2-phenylethanoate)

4,4'-dioxo-β,β-carotene-3,3'-diyl di(2-hydroxy-2-phenylethanoate)

Conditions
ConditionsYield
With Novozyme 435 In methanol; toluene at 37℃; for 6h; Darkness; Enzymatic reaction;55%
(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

(3R,3'R)-3,3′-dihydroxy-β,β′-caroten-4,4′-dione
60760-95-4

(3R,3'R)-3,3′-dihydroxy-β,β′-caroten-4,4′-dione

(3R,3'S)-3,3′-dihydroxy-β,β′-caroten-4,4′-dione
71772-51-5

(3R,3'S)-3,3′-dihydroxy-β,β′-caroten-4,4′-dione

N-(all-trans-Retinoyl)-imidazole
61319-45-7

N-(all-trans-Retinoyl)-imidazole

B

(3R,3'S)-astaxanthin monoretinoate

(3R,3'S)-astaxanthin monoretinoate

Conditions
ConditionsYield
With pyridine; sodium hydride at 20℃; for 3h;A 50%
B 5%
(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

C108H104O22
1010099-33-8

C108H104O22

Conditions
ConditionsYield
With 4 A molecular sieve; silver trifluoromethanesulfonate In dichloromethane at 0℃; for 2h;31%
(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

A

9-Z-3,3′-dihydroxy-4,4′-dione-β,β′-carotene

9-Z-3,3′-dihydroxy-4,4′-dione-β,β′-carotene

B

13-Z-3,3′-dihydroxy-4,4′-dione-β,β′-carotene

13-Z-3,3′-dihydroxy-4,4′-dione-β,β′-carotene

Conditions
ConditionsYield
With iodine-doped titanium dioxide In ethyl acetate at 70℃; for 2h; Reagent/catalyst; Temperature; Solvent;A 22.7%
B 16.9%
In acetone; Petroleum ether at 70℃; for 12h;
With I-TiO2 In ethyl acetate at 70℃; for 2h;
(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

(E)-2-((3-(thiazolidin-3-yl)propyl)imino)acetic acid

(E)-2-((3-(thiazolidin-3-yl)propyl)imino)acetic acid

A

C48H64N2O5S

C48H64N2O5S

B

C56H76N4O6S2

C56H76N4O6S2

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane at 20℃; for 48h;A 10.9%
B 15.7%
(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

(3S,3'S)-15,15'-cis-Astaxanthin

(3S,3'S)-15,15'-cis-Astaxanthin

Conditions
ConditionsYield
With hydrogen; Lindlar's catalyst In dichloromethane
(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

(-)-methoxytrifluoromethylphenylacetyl chloride
39637-99-5

(-)-methoxytrifluoromethylphenylacetyl chloride

Conditions
ConditionsYield
With pyridine at 0℃; for 0.75h; determination of enantiomeric composition of partly racemized carotenols by converting them in to diastereomeric esters, HPLC and NMR (in the presence of Eu(fod)3 shift reagent) analysis;
(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

(-)-camphanic acid chloride
39637-74-6, 104530-16-7

(-)-camphanic acid chloride

C60H76O10

C60H76O10

Conditions
ConditionsYield
With pyridine at 0℃; for 0.666667h;
(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

3,4,3',4'-tetrahydroxy-β,β-carotene
6094-35-5, 28082-20-4

3,4,3',4'-tetrahydroxy-β,β-carotene

Conditions
ConditionsYield
With sodium tetrahydroborate In ethanol
(3S,3'S)-astaxanthin
472-61-7

(3S,3'S)-astaxanthin

A

(3S,3'S)-astaxanthin monosulfate

(3S,3'S)-astaxanthin monosulfate

B

(3S,3'S)-astaxanthin disulfate

(3S,3'S)-astaxanthin disulfate

Conditions
ConditionsYield
With pyridine; chlorosulfonic acid for 2.5h; Ambient temperature; Yield given;
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