Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
Cas:496-12-8
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:496-12-8
Min.Order:5 Kiloliter
FOB Price: $1.2 / 5.0
Type:Manufacturers
inquiry1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ
Cas:496-12-8
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryIsoindoline CAS:496-12-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates,
Cas:496-12-8
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:496-12-8
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
superior quality Appearance:powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application: Used to make a chiral diamine catalyst from L-proline for the
J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Cas:496-12-8
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:496-12-8
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiryOur company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O
Cas:496-12-8
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryGMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,
We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O
Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai
Cas:496-12-8
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryThe process is mature and can be mass produced to 100 kg, with good quality and purity up to 99%.The product has a large stock and can be supplied stably. Package:bottle Application:Drug R&D Transportation:Sealed drying(25℃) Port:ShangHai
high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou
high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,or Intermediates,fine chemicals Transportation:air,sea,courier
Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as
Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali
Cas:496-12-8
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryFactory supply high purity low priceAppearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China
Isoindoline cas 496-12-8Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express
factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
Best quality with low price Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Shanghai
Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai
Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen
Quality assurance, stable process and affordable priceAppearance:detailed see specifications Storage:enquiry Package:according to the clients requirement Application:Pharmaceutical intermediates Transportation:Normal Port:chengdu
high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China
Known for its best quality and competitve price, this chemicals we offered is widely appreciated by our customers.Appearance:White powder Storage:keep sealed and keep from direct light Package:According client's requirements Application:pharmaceutica
high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China
2(toluene-p-sulphonyl)isoindoline
isoindoline
Conditions | Yield |
---|---|
With hydrogen bromide; propionic acid; phenol for 2h; Inert atmosphere; Reflux; | 93% |
With hydrogen bromide; phenol In propionic acid for 2h; Heating; | 61% |
With hydrogen bromide; propionic acid; phenol |
N-(2-furylmethyl)-N-(prop-2-en-1-yl)amine
isoindoline
Conditions | Yield |
---|---|
With hydrogenchloride; sodium hydrogencarbonate 1.) ether, 90 deg C, 32 h, 2.) H2O; | 85% |
2-benzylisoindoline
isoindoline
Conditions | Yield |
---|---|
With palladium on activated charcoal; hydrogen In methanol | 84% |
With iodine; hypophosphorous acid; acetic acid for 12h; Heating; | 75% |
With ethanol; palladium | |
With hydrogen; palladium on activated charcoal In methanol at 20℃; for 8h; | |
With palladium 10% on activated carbon; hydrogen In methanol at 20℃; for 8h; |
Conditions | Yield |
---|---|
With sodium cyanoborohydride In methanol at 25℃; for 3h; | 80% |
phthalimide
isoindoline
Conditions | Yield |
---|---|
With borane-THF In tetrahydrofuran for 14h; Inert atmosphere; Reflux; | 78% |
With borane-THF In tetrahydrofuran for 14h; Heating; | 50% |
With sulfuric acid at 60℃; bei der elektrolytischen Reduktion; |
Conditions | Yield |
---|---|
platinum In tetrahydrofuran | 75% |
With cobalt catalyst; ammonia at 100℃; under 73550.8 Torr; Hydrogenation.Reagens 4: Dioxan; | |
With ammonia; nickel at 100℃; under 73550.8 Torr; Hydrogenation.Reagens 4: Dioxan; |
Conditions | Yield |
---|---|
With ammonia; potassium carbonate In water at 120℃; for 0.333333h; microwave irradiation; | 62% |
With hydrogenchloride; hexamethylenetetramine; triethylamine 1.) CHCl3, reflux, 4 h; 2.) EtOH, 12 h; 3.) reflux, 8 h; | 44% |
Conditions | Yield |
---|---|
With sulfuric acid at 50℃; Electrolysis.Verwendung einer Cadmium-Kathode; | |
With dimethylsulfide borane complex In tetrahydrofuran at 0 - 45℃; for 3h; Inert atmosphere; |
Conditions | Yield |
---|---|
With sulfuric acid at 40℃; Bei der elektrochemischen Reduktion an einer Zink-Amalgam-Kathode unter Normaldruck,bei 5.3 at und bei 8.5 at; |
Conditions | Yield |
---|---|
bei der elektrochemischen Reduktion an einer Blei-Kathode in wss. H2SO4; |
Conditions | Yield |
---|---|
With acetic acid; zinc |
Conditions | Yield |
---|---|
With hydrogenchloride; zinc | |
With hydrogenchloride; tin |
1,2-benzenedimethanamine
isoindoline
Conditions | Yield |
---|---|
With diethyl ether; N-phenylsulfinylamine |
o-chloromethylbenzylamine
A
isoindoline
B
2-isoindolin-2-ylmethyl-benzylamine
o-chloromethylbenzylamine
isoindoline
Conditions | Yield |
---|---|
With sodium hydroxide |
hydrogenchloride
1,3-dihydro-isoindole-2-carboxylic acid amide
isoindoline
Conditions | Yield |
---|---|
at 160 - 170℃; |
Conditions | Yield |
---|---|
at 18 - 20℃; bei elektrolytischen Reduktion an Bleikathoden,zuletz 60grad; |
Conditions | Yield |
---|---|
at 200℃; im Rohr; |
isoindoline
Conditions | Yield |
---|---|
With sulfuric acid | |
With hydrogenchloride at 160 - 170℃; |
isoindoline
Conditions | Yield |
---|---|
With ammonia at 200℃; |
isoindoline
Conditions | Yield |
---|---|
With ammonia at 250℃; im Rohr; |
isoindoline
(2-(piperidin-1-ylmethyl)phenyl)methanamine
water
A
piperidine
B
isoindoline
Conditions | Yield |
---|---|
at 200℃; im Rohr; |
phthalimide
ethanol
sulfuric acid
water
A
isoindoline
B
oxisoindole
Conditions | Yield |
---|---|
under 6251.8 Torr; Elektrochemische Reduktion an einer Zink-Amalgam-Kathode; | |
under 735.5 Torr; Elektrochemische Reduktion an einer Zink-Amalgam-Kathode; | |
under 3898.2 Torr; Elektrochemische Reduktion an einer Zink-Amalgam-Kathode; |
1H-2,3-benzoxazin-1-one
acetic acid
A
isoindoline
B
oxisoindole
C
phthalimide
isoindoline
(3R-trans)-dihydro-2,5-dioxofuran-3,4-diyl diacetate
C16H17NO7
Conditions | Yield |
---|---|
In dichloromethane at 20℃; for 2h; | 100% |
isoindoline
1-fluoro-2-nitro-4-trifluoromethyl-benzene
2-[2-nitro-4-(trifluoromethyl)phenyl]isoindoline
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide at 0 - 20℃; for 2h; | 100% |
isoindoline
di-tert-butyl dicarbonate
tert-butyl isoindoline-2-carboxylate
Conditions | Yield |
---|---|
With triethylamine In dichloromethane | 100% |
With triethylamine In dichloromethane |
Conditions | Yield |
---|---|
With pyridine at 20℃; | 100% |
In pyridine at 20℃; for 20h; |
isoindoline
Conditions | Yield |
---|---|
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 3h; | 100% |
Conditions | Yield |
---|---|
[Y((CH3)4C5Si(CH3)2N(phenyl))(trimethylsilylmethyl)(tetrahydrofuran)2] In benzene at 80℃; for 0.5h; | 99% |
[{Me2Si(C5Me4)(NPh)}Y(CH2SiMe3)(thf)2] In benzene at 80℃; for 0.5h; |
isoindoline
trifluoroacetic anhydride
1-(1,3-dihydro-2H-isoindol-2-yl)-2,2,2-trifluoroethanone
Conditions | Yield |
---|---|
With pyridine; dmap In chloroform at 0 - 20℃; for 4h; | 99% |
With pyridine; dmap In chloroform at 20℃; for 4h; Cooling with ice; | 8.66 g |
isoindoline
Conditions | Yield |
---|---|
Stage #1: N-methyl-4,6-bis(perfluorophenoxy)-1,3,5-triazin-2-amine With N-ethyl-N,N-diisopropylamine In dichloromethane for 0.0833333h; Cooling with ice; Stage #2: isoindoline In dichloromethane at 0 - 20℃; for 72.0833h; | 99% |
isoindoline
2-chloro-5-cyano-6-ethoxy-4-phenylpyridine-3-carboxaldehyde
6-(1,3-Dihydro-isoindol-2-yl)-2-ethoxy-5-formyl-4-phenyl-nicotinonitrile
Conditions | Yield |
---|---|
With triethylamine In tetrahydrofuran for 0.166667h; Heating; | 97% |
isoindoline
4-Chlorophenyl isothiocyanate
N-(4-Chlorophenyl)-1 ,3-dihydro-2H-isoindole-2-carbothioamide
Conditions | Yield |
---|---|
In ethanol | 97% |
isoindoline
4-formylbenzene-1-sulfonyl chloride
4-(1,3-dihydro-isoindole-2-sulfonyl)-benzaldehyde
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 20℃; for 1h; | 96% |
isoindoline
2,4-bis(benzyloxy)-5-bromobenzoic acid
(2,4-bis-benzyloxy-5-bromophenyl)-(1,3-dihydroisoindol-2-yl)methanone
Conditions | Yield |
---|---|
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 3h; | 96% |
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; | 70% |
isoindoline
ethyl trifluoroacetate,
1-(1,3-dihydro-2H-isoindol-2-yl)-2,2,2-trifluoroethanone
Conditions | Yield |
---|---|
In methanol at 45℃; | 96% |
isoindoline
N,N-dimethyl-N'-(1-methoxy-2-methyl-2-propyl) formamidine
Conditions | Yield |
---|---|
Heating; | 95% |
isoindoline
3-methyl-3-phenylcyclopropene
Conditions | Yield |
---|---|
With C39H27(1-)*2C9H12N(1-)*Sm(3+) In toluene at 25℃; for 12h; Inert atmosphere; enantioselective reaction; | 95% |
Conditions | Yield |
---|---|
Stage #1: 3,5-Di-tert-butylphenol With tetrakis(actonitrile)copper(I) hexafluorophosphate; N,N'-di-tert-butylethylenediamine; oxygen at 23℃; under 760.051 Torr; for 4h; Stage #2: isoindoline With oxygen at 50℃; under 760.051 Torr; for 4h; Stage #3: With sodium tetrahydroborate at 0 - 23℃; for 2h; | 95% |
Conditions | Yield |
---|---|
With sodium hydride In tetrahydrofuran for 12h; Inert atmosphere; Reflux; | 95% |
isoindoline
4-chloro-2-methylphenyl isocyanate
Conditions | Yield |
---|---|
In 1,4-dioxane at 20℃; | 94% |
isoindoline
pentacarbonyl(1-methoxybenzylidene)chromium(0)
(CO)5CrC(C6H5)NC8H8
Conditions | Yield |
---|---|
In tetrahydrofuran Isoindoline was added to a THF soln. of (CO)5CrC(OCH3)C6H5. The solvent was removed under vac..; elem.anal.; | 94% |
isoindoline
N,N-dimethyl-N'-tert-butylformamidine
N-(tert-butyliminomethyl)isoindoline
Conditions | Yield |
---|---|
With ammonium sulfate In toluene for 4.5h; Heating; | 93% |
With ammonium sulfate In toluene for 20h; Reflux; Inert atmosphere; | 71% |
isoindoline
(1S,3R,4R)-N-tert-butoxycarbonyl-2-azabicyclo[2.2.1]heptane-3-carboxylic acid
(1S,3R,4R)-N-tert-butoxycarbonyl-3-(N-isoindolinyl)carbonyl-2-azabicyclo[2.2.1]heptane
Conditions | Yield |
---|---|
Stage #1: (1S,3R,4R)-N-tert-butoxycarbonyl-2-azabicyclo[2.2.1]heptane-3-carboxylic acid With benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triethylamine In dichloromethane at 0℃; for 0.25h; Condensation; Stage #2: isoindoline In dichloromethane at 20℃; Acylation; Further stages.; | 93% |
isoindoline
2-Amino-4,6-dichloropyrimidine
4-chloro-6-(1,3-dihydro-2H-isoindol-2-yl)pyrimidin-2-amine
Conditions | Yield |
---|---|
With triethylamine In ethanol at 85℃; for 6h; | 93% |
Conditions | Yield |
---|---|
With 2,8-dibromo-5,5-difluoro-1,3,7,9-tetramethyl-10-phenyl-5H-dipyrrolo[1,2-c:2′,1′-f ][1,3,2]diazaborinin-4-ium-5-uide; 2,6-di-tert-butyl-4-methyl-phenol; oxygen In 1,4-dioxane at 25℃; for 12h; Sealed tube; Irradiation; Green chemistry; | 93% |
isoindoline
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 18h; | 93% |
isoindoline
5-chloro-2,4-dimethoxy-6-methylbenzoic acid
(3-chloro-4,6-dimethoxy-2-methylphenyl)(isoindolin-2-yl)methanone
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine; HATU In N,N-dimethyl-formamide at 20℃; for 12h; | 92% |
isoindoline
(S)-1-tert-butyl 2-methyl 4-oxopyrrolidine-1,2-dicarboxylate
Conditions | Yield |
---|---|
Stage #1: isoindoline; (S)-1-tert-butyl 2-methyl 4-oxopyrrolidine-1,2-dicarboxylate With acetic acid In dichloromethane for 1h; Stage #2: With sodium tris(acetoxy)borohydride In dichloromethane at 20℃; | 92% |
Conditions | Yield |
---|---|
With sodium hydride In tetrahydrofuran for 12h; Inert atmosphere; Reflux; | 92% |
isoindoline
1,3-diphenyl-2-propynone
(E)-3-(2,3-dihydro-1H-2-isoindolyl)-1,3-diphenyl-2-propen-1-one
Conditions | Yield |
---|---|
In diethyl ether for 12h; | 91% |
isoindoline
Trichloroacetyl chloride
2,2,2-trichloro-1-(1,3-dihydro-2H-isoindol-2-yl)ethanone
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 0 - 20℃; for 1h; | 91% |
With triethylamine In chloroform at 20℃; for 1h; Cooling with ice; | 6.59 g |
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