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Kono Chem Co.,Ltd

Superiority konochemical is a leading manufacturer and supplier of chemicals in China. We develop ,produce and distribute high quality pharmaceuticals, intermediates, special chemicals and other fine chemicals. We could give you: 1.Best quali

Best price cosmetic raw material pure natural beta and alpha arbutin

Cas:497-76-7

Min.Order:1 Kilogram

FOB Price: $200.0 / 300.0

Type:Other

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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem’s R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantiti

buy Skin Whitening Arbutin 98% from TOP1 supplier in China

Cas:497-76-7

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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Wuhan ZeShanCheng Biomedical Technology Co., Ltd.

Chinese Name: β- Arbutin English Name: Arbutin CAS No.: 497-76-7 Molecular formula: C12H16O7 Molecular weight: 272.25 Use In medicine, it is used as diuretic, urinary system anti infective, color photography development stabilizer, whitenin

β- Arbutin

Cas:497-76-7

Min.Order:100 Kilogram

FOB Price: $1000.0

Type:Trading Company

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Wuhan Zenuo Biological Medicine Technology Co Ltd

Strict quality control: good raw materials, good quality, Zenuo Biology has always regarded quality as the life of the enterprise. Zenuo Biology has an independent quality control department and long-term cooperation with the third-party detection

Arbutin Manufactuered in China high quality

Cas:497-76-7

Min.Order:100 Gram

Negotiable

Type:Trading Company

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HANWAYS CHEMPHARM CO.,LIMITED

Hanways focus on: -Pharmaceutical raw materials -Chemical raw materials -Food additives -Flavors and fragrances -Feed additives -Plant extracts -Veterinary raw materials We could supply you: -Best quality -Competitive price

Arbutin 497-76-7

Cas:497-76-7

Min.Order:1 Kilogram

FOB Price: $10.0

Type:Trading Company

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Wuhan BJM Pharm Inc.

Wuhan BJM Pharm Inc. was found in 2013, located in Hubei Province, where has long history, rich culture, convenient traffic, beautiful environment and preferential policy. We have two factories in Dezhou, Shandong and Xianning, Hubei. The factor

Beta Arbutin skin whitening 497-76-7/84380-01-8 Factory Supply Purity

Cas:497-76-7

Min.Order:1 Kilogram

FOB Price: $30.0 / 50.0

Type:Other

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Greenutra Resource Inc

Alpha Arbutin Powder Product Name: arbutin Synonyms: 4-hydroxyphenyl-beta-d-glucopyranosid;beta-arbutin;4-HYDROXYPHENYL-BETA-D-GLUCOPYRANOSIDE;ARBUTIN;ARBUTOSIDE;B-D-GLUCOPYRANOSIDE, 4-HYDROXYPHENYL;HYDROQUINONE-BETA-D-GLUCOPYRANOSIDE;HYDRO

Alpha Arbutin Powder

Cas:497-76-7

Min.Order:1 Kilogram

FOB Price: $21.5

Type:Trading Company

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GIHI CHEMICALS CO.,LIMITED

Product Name:Arbutin CAS No.: 497-76-7 Chemical formula: C6H7NO2 Molecular weight: 272.25 Item Specification Appearance White or white-like crystalline powder Melting point,℃

Biggest manufacturer of Arbutin,higher purity, lower price, sample available from gihichem

Cas:497-76-7

Min.Order:1 Gram

FOB Price: $3.0

Type:Lab/Research institutions

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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Assay 98%min -----------------------------------------------------------------------------------------------

High purity Various Specifications Arbutin CAS:497-76-7

Cas:497-76-7

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Manufacturers

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Arbutin supplier in China

Cas:497-76-7

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

buy Skin Whitening Arbutin 98% from TOP1 supplier in China CAS NO.497-76-7

Cas:497-76-7

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

High quality beta-Arbutin CAS 497-76-7 supplied by reliable manufacturer Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/F

High quality beta-Arbutin CAS 497-76-7 supplied by reliable manufacturer

Cas:497-76-7

Min.Order:10 Kilogram

FOB Price: $300.0

Type:Trading Company

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Xi'an Quanao Biotech Co., Ltd.

We are: Focus on the research, production and sale of Plant and Animal extract, Medical intermediate, complete coverage six industries. Product grade: Medicine, Health care product, Cosmetics, Food,Feed, Biopesticide. Hot selling market: Europe,

Cosmetic Field Whitening Arbutin CAS 497-76-7

Cas:497-76-7

Min.Order:1 Kilogram

FOB Price: $160.0 / 165.0

Type:Manufacturers

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Hefei TNJ chemical industry co.,ltd

TNJ is a chemical company since 2001. Our specialization, your Confidence ! We keep committing to meet the needs of both market and customers with our innovative technology, high stable quality products and excellent service. We always combine econ

beta arbutin,brighten your skin

Cas:497-76-7

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

Arbutin

Cas:497-76-7

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price API 99% Arbutin 497-76-7 GMP Manufacturer

Cas:497-76-7

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Xi`an Eastling Biotech Co., Ltd.

497-76-7 - Physico-chemical Properties Molecular Formula C12H16O7 Molar Mass 272.25 Density 1.3582 (rough estimate) Melting Point 195-198°C Boling Point 375.31°C (rough estimate)

Top Quality Natural Arbutin

Cas:497-76-7

Min.Order:1 Kilogram

FOB Price: $35.0 / 49.0

Type:Lab/Research institutions

inquiry

Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality Arbutin

Cas:497-76-7

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

β-Arbutin

Cas:497-76-7

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Arbutin

Cas:497-76-7

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Sinoway Industrial Co., Ltd.

Why is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c

497-76-7

Cas:497-76-7

Min.Order:25 Kilogram

FOB Price: $50.0

Type:Trading Company

inquiry

Hubei DiBo chemical co., LTD

Name: Arbutin CAS no. : 497-76-7 Molecular formula: C12H16O7 Molecular weight:272.25 Product Quality 12 years of chemical raw materials Mature operation of the industry System stability Data storage Security without vulnerability Prod

Arbutin /CAS :497-76-7/raw material/high-quality

Cas:497-76-7

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

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Henan Tianfu Chemical Co., Ltd.

Product Name: Arbutin Synonyms: 4-hydroxyphenyl-beta-d-glucopyranosid;beta-arbutin;4-HYDROXYPHENYL-BETA-D-GLUCOPYRANOSIDE;ARBUTIN;ARBUTOSIDE;B-D-GLUCOPYRANOSIDE, 4-HYDROXYPHENYL;HYDROQUINONE-BETA-D-GLUCOPYRANOSIDE;HYDROQUINONE-BETA-D-G

497-76-7 Arbutin

Cas:497-76-7

Min.Order:1 Gram

FOB Price: $8900.0

Type:Lab/Research institutions

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Leader Biochemical Group

Arbutin Basic information The ideal whitening agent of whitening cosmetics Ursolic acid and α- arbutin Is it suitable for using during the day Uses Product Name: Arbutin Synonyms: 4-hydroxy

China largest Factory supply Natural Beta-Arbutin CAS 497-76-7

Cas:497-76-7

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc. We are specialized in chemical synthesis, process development of

Arbutin Manufacturer

Cas:497-76-7

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

Factory Supply 99% Original Powder Arbutin CAS 497-76-7 with Safe Delivery

Cas:497-76-7

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 497-76-7 with best quality

Cas:497-76-7

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Cosmetic raw material & whitening Alpha Arbutin 99%

Cas:497-76-7

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages High purity, all above 98.5%, no impurities after dissolution We will test each batch to ensure quality OEM and private brand services designed for free Various cap colors available We can also provide MT1 peptide powd

Arbutin

Cas:497-76-7

Min.Order:1 Kilogram

FOB Price: $5.0 / 10.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Product name Beta-Arbutin Purity 99% Cas No. 497-76-7 Molecular Formula C12H16O7 Appearance White powder

Beta-Arbutin

Cas:497-76-7

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Synthetic route

4-hydroxyphenyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside
6129-66-4, 124431-77-2, 125095-10-5, 125095-11-6, 142393-05-3

4-hydroxyphenyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside

arbutin
497-76-7

arbutin

Conditions
ConditionsYield
With ammonia; water In methanol Microwave irradiation;99%
Stage #1: 4-hydroxyphenyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside With sodium methylate In methanol for 4h; Heating / reflux;
Stage #2: With acetic acid In methanol for 0.5h; AcOH was added after cooling; Stirring;
80%
With methanol; sodium methylate
Multi-step reaction with 2 steps
1: acetic anhydride / toluene / 1.5 h / 60 °C
2: ammonium chloride / water / 2 h / 70 °C
View Scheme
With methanol; sodium methylate at 80℃; for 5h;
pentaacetate arbutin

pentaacetate arbutin

arbutin
497-76-7

arbutin

Conditions
ConditionsYield
With methanol; sodium methylate at 50℃; for 2h; Large scale;95.2%
p-methoxyphenyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside
2872-65-3, 14581-81-8, 17042-40-9, 84380-06-3, 105260-62-6

p-methoxyphenyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside

arbutin
497-76-7

arbutin

Conditions
ConditionsYield
With copper(I) oxide; sodium methylate In methanol at 0 - 80℃; for 4h;95%
β-D-glucose
492-61-5

β-D-glucose

p-Coumaric Acid
7400-08-0

p-Coumaric Acid

arbutin
497-76-7

arbutin

Conditions
ConditionsYield
With SArbutin 5 In aq. phosphate buffer at 37℃; for 24h; pH=7.0;92%
hydroquinone
123-31-9

hydroquinone

2-nitrophenyl β-D-glucopyranoside
2816-24-2

2-nitrophenyl β-D-glucopyranoside

arbutin
497-76-7

arbutin

Conditions
ConditionsYield
With Na acetate buffer; butan-1-ol for 8h; β-glucuronidase from bovine liver;91.2%
4-acetoxyphenyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside
14698-56-7

4-acetoxyphenyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside

arbutin
497-76-7

arbutin

Conditions
ConditionsYield
With ammonium chloride In water at 70℃; for 2h; Concentration;90%
With di(n-butyl)tin oxide In methanol for 8h; Heating;87.7%
Stage #1: 4-acetoxyphenyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside With sodium methylate In methanol for 4h; Heating / reflux; 28% NaOMe;
Stage #2: With acetic acid In methanol for 0.5h; AcOH was added after cooling; Stirring;
81%
D-glucose
50-99-7

D-glucose

hydroquinone
123-31-9

hydroquinone

A

arbutin
497-76-7

arbutin

B

4-hydroxyphenyl α-D-glucopyranoside
497-76-7, 84380-01-8, 90706-69-7, 125095-12-7, 125095-13-8

4-hydroxyphenyl α-D-glucopyranoside

Conditions
ConditionsYield
With toluene-4-sulfonic acid In dimethyl sulfoxide at 100℃; for 10h;A 4%
B 11%
hydroquinone
123-31-9

hydroquinone

α-D-glucopyranosyl-1-phosphate
59-56-3

α-D-glucopyranosyl-1-phosphate

arbutin
497-76-7

arbutin

Conditions
ConditionsYield
With recombinant cellobiosephosphorylase from C. thermocellum In ethyl acetate at 50℃; for 48h; pH=6.5; Enzymatic reaction;1.6%
Conditions
ConditionsYield
With Prunus dulcis var. amara β-glucoside glucohydrolase, 68 kDa In aq. phosphate buffer; tert-butyl alcohol at 50℃; for 24h; pH=7; Enzymatic reaction;0.14%
4-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyloxy)phenylbenzoate
380153-99-1

4-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyloxy)phenylbenzoate

arbutin
497-76-7

arbutin

Conditions
ConditionsYield
With methanol; ammonia
UDP-glucose
133-89-1

UDP-glucose

hydroquinone
123-31-9

hydroquinone

arbutin
497-76-7

arbutin

Conditions
ConditionsYield
in Gegenwart eines Enzym-Praeparats aus Weizenkeimen;
With arbutin synthase Product distribution; Further Variations:; Reaction partners; Reagents; Enzymatic reaction;
hydroquinone
123-31-9

hydroquinone

arbutin
497-76-7

arbutin

Conditions
ConditionsYield
biotransformation with Rauwolfia cell culture;
(E)-(R)-6-Hydroxy-2,6-dimethyl-octa-2,7-dienoic acid (2R,3R,4S,5R,6S)-3,4,5-triacetoxy-6-(4-acetoxy-phenoxy)-tetrahydro-pyran-2-ylmethyl ester

(E)-(R)-6-Hydroxy-2,6-dimethyl-octa-2,7-dienoic acid (2R,3R,4S,5R,6S)-3,4,5-triacetoxy-6-(4-acetoxy-phenoxy)-tetrahydro-pyran-2-ylmethyl ester

A

(6R)-2-trans-2,6-dimethyl-6-hydroxy-2,7-octadienoic acid
83945-54-4

(6R)-2-trans-2,6-dimethyl-6-hydroxy-2,7-octadienoic acid

B

arbutin
497-76-7

arbutin

Conditions
ConditionsYield
With sodium hydroxide In methanol for 2h; Heating;A 76 mg
B 191 mg
4-hydroxyphenyl benzoate
2444-19-1

4-hydroxyphenyl benzoate

arbutin
497-76-7

arbutin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: quinoline; silver oxide
2: ammonia; methanol
View Scheme
α-D-Glucopyranoside 1-(disodium phosphate)
56401-20-8

α-D-Glucopyranoside 1-(disodium phosphate)

hydroquinone
123-31-9

hydroquinone

arbutin
497-76-7

arbutin

Conditions
ConditionsYield
With cellobiose phosphorylase from Clostridium thermocellum In ethyl acetate at 50℃; for 48h; pH=6.5; Solvent; Enzymatic reaction;
alpha-D-glucopyranose
492-62-6

alpha-D-glucopyranose

arbutin
497-76-7

arbutin

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: sodium acetate / 4 h / 100 - 130 °C / 760.05 Torr / Large scale
2.1: triethylamine; boron trifluoride diethyl etherate / dichloromethane; toluene / 11 h / 30 - 40 °C / 760.05 Torr / Inert atmosphere; Large scale
2.2: 2 h / 15 - 20 °C / Large scale
3.1: methanol; sodium methylate / 2 h / 50 °C / Large scale
View Scheme
C21H22O10

C21H22O10

A

1-(4-hydroxyphenyl)-1,3-propanediol
22805-46-5

1-(4-hydroxyphenyl)-1,3-propanediol

B

arbutin
497-76-7

arbutin

Conditions
ConditionsYield
With sodium tetrahydroborate In ethanol at 0 - 20℃;A 2 mg
B 1 mg
D-glucose
50-99-7

D-glucose

benzene
71-43-2

benzene

A

hydroquinone
123-31-9

hydroquinone

B

arbutin
497-76-7

arbutin

Conditions
ConditionsYield
With arbutin synthase from Rauvolfia serpentina; cytochrome P450-BM3 monooxygenase from Bacillus megaterium A82F/V78F/A328F triple mutant In aq. phosphate buffer at 30℃; for 5h; pH=8;
β-D-glucose
492-61-5

β-D-glucose

arbutin
497-76-7

arbutin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Prunus dulcis var. amara β-glucoside glucohydrolase, 68 kDa / aq. phosphate buffer / 70 h / 50 °C / pH 6 / Enzymatic reaction
2: Prunus dulcis var. amara β-glucoside glucohydrolase, 68 kDa / aq. phosphate buffer; tert-butyl alcohol / 24 h / 50 °C / pH 7 / Enzymatic reaction
View Scheme
β-D-glucose pentaacetate
604-69-3

β-D-glucose pentaacetate

arbutin
497-76-7

arbutin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: triethylamine; boron trifluoride diethyl etherate / dichloromethane / 10 h / 0 - 50 °C
2: sodium methylate; methanol / 5 h / 80 °C
View Scheme
Multi-step reaction with 2 steps
1: triethylamine; boron trifluoride diethyl etherate / dichloromethane / 10 h / 0 - 50 °C
2: sodium methylate; methanol / 5 h / 80 °C
View Scheme
4-hydroxy-benzoic acid
99-96-7

4-hydroxy-benzoic acid

arbutin
497-76-7

arbutin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 4-hydroxybenzoate 1-hydroxylase MNX1 from yeast Candida parapsilosis strain CDC317 / 2 h / Enzymatic reaction
2: arbutin synthase (Q9AR73.1) from Rauvolfia serpentina / Enzymatic reaction
View Scheme
β-D-glucose
492-61-5

β-D-glucose

hydroquinone
123-31-9

hydroquinone

arbutin
497-76-7

arbutin

Conditions
ConditionsYield
With arbutin synthase (Q9AR73.1) from Rauvolfia serpentina Reagent/catalyst; Enzymatic reaction;
p-Coumaric Acid
7400-08-0

p-Coumaric Acid

arbutin
497-76-7

arbutin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: NADH / aq. phosphate buffer / 8 h / 37 °C / pH 7.0 / Enzymatic reaction
2: arbutin synthase (Q9AR73.1) from Rauvolfia serpentina / Enzymatic reaction
View Scheme
Multi-step reaction with 4 steps
1.1: feruloyl-CoA synthetase / Enzymatic reaction
1.2: Enzymatic reaction
2.1: vanillin dehydrogenase from genom of Pseudomonas putida KT2440 (NC_002947.4) / Enzymatic reaction
3.1: 4-hydroxybenzoate 1-hydroxylase MNX1 from yeast Candida parapsilosis strain CDC317 / 2 h / Enzymatic reaction
4.1: arbutin synthase (Q9AR73.1) from Rauvolfia serpentina / Enzymatic reaction
View Scheme
Multi-step reaction with 4 steps
1: E. coli (pET28a-TtAdo-BLPad) / aq. phosphate buffer / 6 h / 37 °C / pH 7.0 / Enzymatic reaction
2: vanillin dehydrogenase from genom of Pseudomonas putida KT2440 (NC_002947.4) / Enzymatic reaction
3: 4-hydroxybenzoate 1-hydroxylase MNX1 from yeast Candida parapsilosis strain CDC317 / 2 h / Enzymatic reaction
4: arbutin synthase (Q9AR73.1) from Rauvolfia serpentina / Enzymatic reaction
View Scheme
Multi-step reaction with 5 steps
1: Bacillus licheniformis strain CGMCC 7172 phenolic acid decarboxylase / 6 h / Enzymatic reaction
2: oxygen; Thielavia terrestris NRRL 8126 aromatic dioxygenase TtAdo (XP_003653923) / 37 °C / pH 7.0 / Enzymatic reaction
3: vanillin dehydrogenase from genom of Pseudomonas putida KT2440 (NC_002947.4) / Enzymatic reaction
4: 4-hydroxybenzoate 1-hydroxylase MNX1 from yeast Candida parapsilosis strain CDC317 / 2 h / Enzymatic reaction
5: arbutin synthase (Q9AR73.1) from Rauvolfia serpentina / Enzymatic reaction
View Scheme
4-Vinylphenol
2628-17-3

4-Vinylphenol

arbutin
497-76-7

arbutin

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: oxygen; Thielavia terrestris NRRL 8126 aromatic dioxygenase TtAdo (XP_003653923) / 37 °C / pH 7.0 / Enzymatic reaction
2: vanillin dehydrogenase from genom of Pseudomonas putida KT2440 (NC_002947.4) / Enzymatic reaction
3: 4-hydroxybenzoate 1-hydroxylase MNX1 from yeast Candida parapsilosis strain CDC317 / 2 h / Enzymatic reaction
4: arbutin synthase (Q9AR73.1) from Rauvolfia serpentina / Enzymatic reaction
View Scheme
4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

arbutin
497-76-7

arbutin

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: vanillin dehydrogenase from genom of Pseudomonas putida KT2440 (NC_002947.4) / Enzymatic reaction
2: 4-hydroxybenzoate 1-hydroxylase MNX1 from yeast Candida parapsilosis strain CDC317 / 2 h / Enzymatic reaction
3: arbutin synthase (Q9AR73.1) from Rauvolfia serpentina / Enzymatic reaction
View Scheme
allyl bromide
106-95-6

allyl bromide

arbutin
497-76-7

arbutin

(2S,3R,4S,5S,6R)-2-(4-Allyloxy-phenoxy)-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol
848940-03-4

(2S,3R,4S,5S,6R)-2-(4-Allyloxy-phenoxy)-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 24h;100%
Stage #1: arbutin With sodium hydroxide
Stage #2: allyl bromide In N,N-dimethyl-formamide for 24h;
99%
vinyl ester of 3-phenylpropionic acid
54519-07-2

vinyl ester of 3-phenylpropionic acid

arbutin
497-76-7

arbutin

6'-O-(3-phenylpropionyl)arbutin
1277161-57-5

6'-O-(3-phenylpropionyl)arbutin

Conditions
ConditionsYield
With immobilized lipase from Penicillium expansum In tetrahydrofuran at 50℃; for 4h; Enzymatic reaction; regioselective reaction;93%
vinyl acetate
108-05-4

vinyl acetate

arbutin
497-76-7

arbutin

6'-O-acetylarbutin
10338-88-2

6'-O-acetylarbutin

Conditions
ConditionsYield
With CSL lipase In tetrahydrofuran at 60℃; for 2.5h; Temperature; Reagent/catalyst; Microwave irradiation;92.5%
trityl chloride
76-83-5

trityl chloride

arbutin
497-76-7

arbutin

6-O-triphenylmethylarbutin
180297-88-5

6-O-triphenylmethylarbutin

Conditions
ConditionsYield
With pyridine at 20℃; for 23h; tritylation;91%
10-undecenoic acid
112-38-9

10-undecenoic acid

arbutin
497-76-7

arbutin

6-O-ω-undecylenoyl p-hydroxyphenyl β-D-glucopyranoside

6-O-ω-undecylenoyl p-hydroxyphenyl β-D-glucopyranoside

Conditions
ConditionsYield
Candida antarctica-derived lipase In 1,4-dioxane; dimethyl sulfoxide at 40℃; for 168h; Product distribution / selectivity; Molecular sieve;91%
Candida antarctica-derived lipase In 1,4-dioxane at 40℃; for 168h; Product distribution / selectivity; Molecular sieve;
vinyl ester of 4-phenylbutyric acid
95063-02-8

vinyl ester of 4-phenylbutyric acid

arbutin
497-76-7

arbutin

6'-O-(4-phenylbutyryl)arbutin
1277161-61-1

6'-O-(4-phenylbutyryl)arbutin

Conditions
ConditionsYield
With immobilized lipase from Penicillium expansum In tetrahydrofuran at 50℃; for 5h; Enzymatic reaction; regioselective reaction;91%
vinyl ester of 5-phenylvaleric acid
1186473-08-4

vinyl ester of 5-phenylvaleric acid

arbutin
497-76-7

arbutin

6'-O-(5-phenylvaleryl)arbutin
1277161-64-4

6'-O-(5-phenylvaleryl)arbutin

Conditions
ConditionsYield
With immobilized lipase from Penicillium expansum In tetrahydrofuran at 50℃; for 5.5h; Enzymatic reaction; regioselective reaction;90%
cinnamic acid vinyl ester
17719-70-9, 3098-92-8

cinnamic acid vinyl ester

arbutin
497-76-7

arbutin

6'-O-cinnamoyl-arbutin
221688-07-9

6'-O-cinnamoyl-arbutin

Conditions
ConditionsYield
With immobilized lipase from Penicillium expansum In tetrahydrofuran at 50℃; for 68h; Enzymatic reaction; regioselective reaction;88%
vinyl ester of phenylacetic acid
18120-64-4

vinyl ester of phenylacetic acid

arbutin
497-76-7

arbutin

6'-O-phenylacetyl-arbutin
1277161-53-1

6'-O-phenylacetyl-arbutin

Conditions
ConditionsYield
With immobilized lipase from Penicillium expansum In tetrahydrofuran at 50℃; for 72h; Enzymatic reaction; regioselective reaction;87%
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