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Kono Chem Co.,Ltd

About us We are a Professionally Managed Biotech Company exclusively into the manufacturing, Marketing and Exporting of Plant Extracts and Health Care Products.There are 15 experts in our research team. We insist in innovation and pr

Matrine

Cas:519-02-8

Min.Order:1 Kilogram

FOB Price: $300.0

Type:Other

inquiry

Greenutra Resource Inc

Product Name: Matrine-Sophora flavescenns Ait Extract Apperance:White fine powder Active ingredients: Matrine Specification:98%.99% by HPLC Molecular Formula: C15H24N2O Molecular Weight: 248.36

Kushenin 98% /Matrine

Cas:519-02-8

Min.Order:1 Kilogram

FOB Price: $25.0

Type:Trading Company

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Matrine supplier in China

Cas:519-02-8

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Assay (Ursolic acid) 98%min 98.22% ----------------------------------------------------------------

High purity 519-02-8 matrine

Cas:519-02-8

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Trading Company

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Hebei yanxi chemical co.,LTD.

Hebei yanxi chemical co., LTD is a professional research, development and production 2-phenylacetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low carbon environ

Matrine with high purity

Cas:519-02-8

Min.Order:100 Gram

FOB Price: $2.0

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

Maufacturer supply Matrine CAS 519-02-8 at reasonable price Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives

Maufacturer supply Matrine CAS 519-02-8 at reasonable price

Cas:519-02-8

Min.Order:10 Kilogram

FOB Price: $10.0

Type:Trading Company

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Xi'an Quanao Biotech Co., Ltd.

We are: Focus on the research, production and sale of Plant and Animal extract, Medical intermediate, complete coverage six industries. Product grade: Medicine, Health care product, Cosmetics, Food,Feed, Biopesticide. Hot selling market: Europe,

Top Grade Supply Sophora Flavescens Root Extract Matrine Powder 10%

Cas:519-02-8

Min.Order:1 Kilogram

FOB Price: $1.0 / 3.0

Type:Manufacturers

inquiry

Baoding Faithful Industry Co., Ltd.

Sales: 1.24hours to reply your E-mail 2.Market information trend share with customers Suggestion for purchase decision Reputation: 1.Implementing contract terms strictly 2.Timely solve any discrepancy or goods claims Take our responsibility for loss

Herbal 10: 1 Maca Extract Powder Maca Root Extract

Cas:519-02-8

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price API 99% Matrine 519-02-8 GMP Manufacturer

Cas:519-02-8

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Xi`an Eastling Biotech Co., Ltd.

Matrine CAS: 519-02-8 Molecular Formula: C15H24N2O Home Product Category Biomedicine Chinese herbal extracts 519-02-8 519-02-8 - Names and Identifiers Name Matrine Synonyms MATRENE Matrine MATRINE Matrines

Top Quality Natural Matrine

Cas:519-02-8

Min.Order:1 Kilogram

FOB Price: $35.0 / 49.0

Type:Lab/Research institutions

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Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality Matrine

Cas:519-02-8

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

Matrine Powder

Cas:519-02-8

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

Matrine Manufacturer/High quality/Best price/In stock

Cas:519-02-8

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Matrine

Cas:519-02-8

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hubei DiBo chemical co., LTD

Name:Matrine CAS NO: 519-02-8 Grade:Medical chemical industry, agricultural industry Product Quality 12 years of chemical raw materials Mature operation of the industry System stability Data storage Security without vulnerability Product

Matrine CAS: 519-02-8 Chinese manufacturers high-quality

Cas:519-02-8

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

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LIDE PHARMACEUTICALS LIMITED

1.100% natural product ,without any synthetize ingredient. 2. Manufacturer direct supply. 3.Delivery Time: Immediate delivery. 4.Guaranteed quality /high purity/Competitive Price/can be supplied from milligrams to grams/COA and HP

Maca powder (Pure Natural)

Cas:519-02-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Our advantage:Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scient

TIANFU-CHEM Matrine

Cas:519-02-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

Sophora flavescens extract CAS 519-02-8 Matrine

Cas:519-02-8

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 519-02-8 with competitive price

Cas:519-02-8

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Name: Matrine Synonyms: (5beta)-matridin-15-one CAS:519-02-8 MF: C15H24N2O Appearance:White powder Storage:Store in cool and dry place, away from sun light. Package:25kg/drum Application:APIs Transportation:By sea or by air Port:Qingdao Por

Matrine CAS:519-02-8

Cas:519-02-8

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Appearance:White solid Storage:Sealed in dry,2-8°C Package:25kg/drum Application:(+)-Matrine is an alkaloid compound extracted from the roots of Sophora species which maintain anti-inflammatory, anti-cancer and a host of other positive pharmacologic

HANWAYS CHEMPHARM CO.,LIMITED

Hanways chempharm is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. The marketing department is located in Wuhan. We have two GMP facilities in Hubei Pr

Organic Pure C Extract Powder Food Grade 98% Matrine Extract

Cas:519-02-8

Min.Order:1 Kilogram

FOB Price: $200.0 / 400.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1H,5H,10H-Dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one, dodecahydro-, (7aS,13aR,13bR,13cS)- 519-02-8

Cas:519-02-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

DB BIOTECH CO., LTD

Quick Details CAS No.: 519-02-8 Other Names: alkaloid MF: C15H24N2O2.H2O EINECS No.: 519-02-8 Place of O

High quality Matrine in bulk supply

Cas:519-02-8

Min.Order:1 Kilogram

FOB Price: $30.0

Type:Trading Company

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

Natural Pure Sophora root extract matrinee / matrine extraction with best price CAS 519-02-8

Cas:519-02-8

Min.Order:1 Kilogram

FOB Price: $1.0 / 3.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

matrine (botanic source insecticide-from the root of the sophora,flavescens,ait.) cas reg.:519-02-8 molecular formula:c15h24n2o molecular weight:248.36 specification: 90%-98% technical grade( white crystal powder) solubility: easy to soluble

Matrine

Cas:519-02-8

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1H,5H,10H-Dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one, dodecahydro-, (7aS,13aR,13bR,13cS)-

Cas:519-02-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

Matrine CAS519-02-8

Cas:519-02-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:519-02-8

Cas:519-02-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

Conditions
ConditionsYield
With ammonium sulfate; tin(ll) chloride In water at 50℃; for 4h; Reagent/catalyst; Solvent; Temperature;96.9%
With tris(pentafluorophenyl)borate; phenylsilane In dichloromethane at 60℃; for 8h; Inert atmosphere; Schlenk technique; Green chemistry;82%
(6aS,11aR,11cS)-4,8-Dioxo-decahydro-3a,7a-diaza-benzo[de]anthracene-9,9-dicarboxylic acid dimethyl ester

(6aS,11aR,11cS)-4,8-Dioxo-decahydro-3a,7a-diaza-benzo[de]anthracene-9,9-dicarboxylic acid dimethyl ester

(+)-matrine
519-02-8

(+)-matrine

Conditions
ConditionsYield
With hydrogenchloride; dimethylsulfide borane complex; water 2.) reflux; Yield given; Multistep reaction;
(-)-sophocarpine

(-)-sophocarpine

(+)-matrine
519-02-8

(+)-matrine

Conditions
ConditionsYield
With nickel Hydrogenation;
(-)-sophoramine

(-)-sophoramine

(+)-matrine
519-02-8

(+)-matrine

Conditions
ConditionsYield
With nickel Hydrogenation;
oxymatrine

oxymatrine

(+)-matrine
519-02-8

(+)-matrine

Conditions
ConditionsYield
With sulfur dioxide
t-butyl nicotinate
65321-36-0

t-butyl nicotinate

(+)-matrine
519-02-8

(+)-matrine

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1: 90 percent / H2 / Pd/C
2: Et3N
3: acetone
4: 18 percent / lauroyl peroxide / benzene / Heating
5: lauroyl peroxide, 2-propanol / Heating
6: 90 percent / CF3COOH / CH2Cl2
8: 1.) BH3*Me2S, 2.) HCl, H2O / 2.) reflux
View Scheme
1,4,5,6-tetrahydro-pyridine-3-carboxylic acid tert-butyl ester
4695-77-6

1,4,5,6-tetrahydro-pyridine-3-carboxylic acid tert-butyl ester

(+)-matrine
519-02-8

(+)-matrine

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: Et3N
2: acetone
3: 18 percent / lauroyl peroxide / benzene / Heating
4: lauroyl peroxide, 2-propanol / Heating
5: 90 percent / CF3COOH / CH2Cl2
7: 1.) BH3*Me2S, 2.) HCl, H2O / 2.) reflux
View Scheme
1-allyl-2-oxo-1,4-dihydro-2H-pyridine-3,3-dicarboxylic acid dimethyl ester
208714-36-7

1-allyl-2-oxo-1,4-dihydro-2H-pyridine-3,3-dicarboxylic acid dimethyl ester

(+)-matrine
519-02-8

(+)-matrine

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 30 percent / lauroyl peroxide / benzene / Heating
2: lauroyl peroxide, 2-propanol / Heating
3: 90 percent / CF3COOH / CH2Cl2
5: 1.) BH3*Me2S, 2.) HCl, H2O / 2.) reflux
View Scheme
Multi-step reaction with 6 steps
1: 30 percent / lauroyl peroxide / benzene / Heating
2: 80 percent / lauroyl peroxide / benzene
3: lauroyl peroxide, 2-propanol / Heating
4: 90 percent / CF3COOH / CH2Cl2
6: 1.) BH3*Me2S, 2.) HCl, H2O / 2.) reflux
View Scheme
Multi-step reaction with 5 steps
1: 18 percent / lauroyl peroxide / benzene / Heating
2: lauroyl peroxide, 2-propanol / Heating
3: 90 percent / CF3COOH / CH2Cl2
5: 1.) BH3*Me2S, 2.) HCl, H2O / 2.) reflux
View Scheme
1-chloroacetyl-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid tert-butyl ester

1-chloroacetyl-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid tert-butyl ester

(+)-matrine
519-02-8

(+)-matrine

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: acetone
2: 18 percent / lauroyl peroxide / benzene / Heating
3: lauroyl peroxide, 2-propanol / Heating
4: 90 percent / CF3COOH / CH2Cl2
6: 1.) BH3*Me2S, 2.) HCl, H2O / 2.) reflux
View Scheme
2-allylcarbamoyl-2-(3-oxo-propyl)-malonic acid dimethyl ester

2-allylcarbamoyl-2-(3-oxo-propyl)-malonic acid dimethyl ester

(+)-matrine
519-02-8

(+)-matrine

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: B(OH)3 / toluene / Heating
2: 30 percent / lauroyl peroxide / benzene / Heating
3: lauroyl peroxide, 2-propanol / Heating
4: 90 percent / CF3COOH / CH2Cl2
6: 1.) BH3*Me2S, 2.) HCl, H2O / 2.) reflux
View Scheme
Multi-step reaction with 7 steps
1: B(OH)3 / toluene / Heating
2: 30 percent / lauroyl peroxide / benzene / Heating
3: 80 percent / lauroyl peroxide / benzene
4: lauroyl peroxide, 2-propanol / Heating
5: 90 percent / CF3COOH / CH2Cl2
7: 1.) BH3*Me2S, 2.) HCl, H2O / 2.) reflux
View Scheme
Multi-step reaction with 6 steps
1: B(OH)3 / toluene / Heating
2: 18 percent / lauroyl peroxide / benzene / Heating
3: lauroyl peroxide, 2-propanol / Heating
4: 90 percent / CF3COOH / CH2Cl2
6: 1.) BH3*Me2S, 2.) HCl, H2O / 2.) reflux
View Scheme
1-ethoxythiocarbonylsulfanylacetyl-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid tert-butyl ester
208714-37-8

1-ethoxythiocarbonylsulfanylacetyl-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid tert-butyl ester

(+)-matrine
519-02-8

(+)-matrine

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 18 percent / lauroyl peroxide / benzene / Heating
2: lauroyl peroxide, 2-propanol / Heating
3: 90 percent / CF3COOH / CH2Cl2
5: 1.) BH3*Me2S, 2.) HCl, H2O / 2.) reflux
View Scheme
(6aS,11aR,11bS,11cS)-4,8-Dioxo-octahydro-3a,7a-diaza-benzo[de]anthracene-9,9,11b-tricarboxylic acid dimethyl ester

(6aS,11aR,11bS,11cS)-4,8-Dioxo-octahydro-3a,7a-diaza-benzo[de]anthracene-9,9,11b-tricarboxylic acid dimethyl ester

(+)-matrine
519-02-8

(+)-matrine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
2: 1.) BH3*Me2S, 2.) HCl, H2O / 2.) reflux
View Scheme
(6aS,11aR,11bS,11cS)-4,8-Dioxo-octahydro-3a,7a-diaza-benzo[de]anthracene-9,9,11b-tricarboxylic acid 11b-tert-butyl ester 9,9-dimethyl ester

(6aS,11aR,11bS,11cS)-4,8-Dioxo-octahydro-3a,7a-diaza-benzo[de]anthracene-9,9,11b-tricarboxylic acid 11b-tert-butyl ester 9,9-dimethyl ester

(+)-matrine
519-02-8

(+)-matrine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 90 percent / CF3COOH / CH2Cl2
3: 1.) BH3*Me2S, 2.) HCl, H2O / 2.) reflux
View Scheme
1-[5-(5-tert-butoxycarbonyl-3,4-dihydro-2H-pyridin-1-yl)-2-ethoxythiocarbonylsulfanyl-5-oxo-pentyl]-2-oxo-1,4-dihydro-2H-pyridine-3,3-dicarboxylic acid dimethyl ester
208714-38-9

1-[5-(5-tert-butoxycarbonyl-3,4-dihydro-2H-pyridin-1-yl)-2-ethoxythiocarbonylsulfanyl-5-oxo-pentyl]-2-oxo-1,4-dihydro-2H-pyridine-3,3-dicarboxylic acid dimethyl ester

(+)-matrine
519-02-8

(+)-matrine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: lauroyl peroxide, 2-propanol / Heating
2: 90 percent / CF3COOH / CH2Cl2
4: 1.) BH3*Me2S, 2.) HCl, H2O / 2.) reflux
View Scheme
Multi-step reaction with 5 steps
1: 80 percent / lauroyl peroxide / benzene
2: lauroyl peroxide, 2-propanol / Heating
3: 90 percent / CF3COOH / CH2Cl2
5: 1.) BH3*Me2S, 2.) HCl, H2O / 2.) reflux
View Scheme
11-ethoxythiocarbonylsulfanyl-4,8-dioxo-octahydro-3a,7a-diaza-benzo[de]anthracene-9,9,11b-tricarboxylic acid 11b-tert-butyl ester 9,9-dimethyl ester

11-ethoxythiocarbonylsulfanyl-4,8-dioxo-octahydro-3a,7a-diaza-benzo[de]anthracene-9,9,11b-tricarboxylic acid 11b-tert-butyl ester 9,9-dimethyl ester

(+)-matrine
519-02-8

(+)-matrine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: lauroyl peroxide, 2-propanol / Heating
2: 90 percent / CF3COOH / CH2Cl2
4: 1.) BH3*Me2S, 2.) HCl, H2O / 2.) reflux
View Scheme
Conditions
ConditionsYield
With hydrogen; nickel In water at 20℃; for 8h;
Oxymatrine
16837-52-8

Oxymatrine

(+)-matrine
519-02-8

(+)-matrine

Conditions
ConditionsYield
With hydrazine hydrate In ethanol; water at 80℃; for 48h; Reagent/catalyst; Solvent; Temperature;409.5 g
(+)-matrine
519-02-8

(+)-matrine

matrinic acid
519-08-4, 22272-82-8

matrinic acid

Conditions
ConditionsYield
With sodium hydroxide In water at 90℃; for 12h; Reagent/catalyst; Solvent;99%
With potassium hydroxide In water at 20℃; Reflux;98.3%
Stage #1: (+)-matrine With sodium hydroxide for 9h; Reflux;
Stage #2: With hydrogenchloride In water at 20℃;
98%
(+)-matrine
519-02-8

(+)-matrine

matrinic acid

matrinic acid

Conditions
ConditionsYield
With potassium hydroxide In water at 20℃; for 9h; Reflux;98.3%
carbonic acid dimethyl ester
616-38-6

carbonic acid dimethyl ester

(+)-matrine
519-02-8

(+)-matrine

4-methoxycarbonylmatrine

4-methoxycarbonylmatrine

Conditions
ConditionsYield
With n-butyllithium; diisopropylamine In tetrahydrofuran at -78 - 0℃; for 3h; Inert atmosphere;98%
With n-butyllithium; diisopropylamine In tetrahydrofuran at -78 - 20℃; for 1h; Inert atmosphere;97%
With n-butyllithium; diisopropylamine In tetrahydrofuran at -78 - 20℃; for 1h; Inert atmosphere;94%
Stage #1: (+)-matrine With n-butyllithium; diisopropylamine In tetrahydrofuran at -78℃; for 1h;
Stage #2: carbonic acid dimethyl ester In tetrahydrofuran at -78 - 20℃; for 4.5h;
74%
methanol
67-56-1

methanol

(+)-matrine
519-02-8

(+)-matrine

C16H28N2O2
109616-04-8

C16H28N2O2

Conditions
ConditionsYield
Stage #1: (+)-matrine With hydrogenchloride In water for 6h; Reflux;
Stage #2: methanol In water at 20℃; for 3h;
97%
Stage #1: (+)-matrine With sodium hydroxide for 9h; Reflux;
Stage #2: methanol With hydrogenchloride In water for 2h; Reflux;
76%
Stage #1: (+)-matrine With sodium hydroxide In water for 9h; Reflux;
Stage #2: methanol With hydrogenchloride In water for 2h; Reflux;
diphenyldisulfane
882-33-7

diphenyldisulfane

(+)-matrine
519-02-8

(+)-matrine

14-phenylthio matrine

14-phenylthio matrine

Conditions
ConditionsYield
Stage #1: (+)-matrine With n-butyllithium; N-ethyl-N,N-diisopropylamine In tetrahydrofuran; hexane at -78 - 25℃; for 1.25h; Inert atmosphere; Green chemistry;
Stage #2: diphenyldisulfane In tetrahydrofuran; hexane Reagent/catalyst; Inert atmosphere; Green chemistry;
96%
Stage #1: (+)-matrine With lithium diisopropyl amide In tetrahydrofuran; hexane at 25℃; for 1h;
Stage #2: diphenyldisulfane In tetrahydrofuran; hexane at 25℃; for 2h;
96%
With n-butyllithium; diisopropylamine In tetrahydrofuran; hexane at -78 - 20℃; for 2h;96%
Conditions
ConditionsYield
With lithium aluminium tetrahydride In diethyl ether for 10h; Reflux;95%
With lithium aluminium tetrahydride In tetrahydrofuran at 0℃; for 10.1667h; Reflux;88%
With lithium aluminium tetrahydride In tetrahydrofuran Reflux;88%
With lithium aluminium tetrahydride In tetrahydrofuran for 10h; Reflux;
(+)-matrine
519-02-8

(+)-matrine

matrinic acid
519-08-4, 22272-82-8

matrinic acid

Conditions
ConditionsYield
With water; sodium hydroxide at 100℃; for 10h;95%
(+)-matrine
519-02-8

(+)-matrine

matrine hydrochloride

matrine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In water for 3h;93%
N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

(+)-matrine
519-02-8

(+)-matrine

14-formyl-15-chloromatrine

14-formyl-15-chloromatrine

Conditions
ConditionsYield
Stage #1: N,N-dimethyl-formamide With trichlorophosphate In dichloromethane at 0℃; for 1h; Vilsmeier-Haack Formylation;
Stage #2: (+)-matrine In dichloromethane at 20℃; for 9h; Vilsmeier-Haack Formylation;
Stage #3: With sodium hydroxide In dichloromethane; water at 60℃; for 2h; pH=8 - 9; Vilsmeier-Haack Formylation;
92%
With trichlorophosphate In dichloromethane at 0 - 60℃; for 11h; Vilsmeier-Haack Formylation;92%
With trichlorophosphate In dichloromethane at 0 - 60℃; for 11h; Vilsmeier-Haack Formylation;92%
Stage #1: N,N-dimethyl-formamide With trichlorophosphate In dichloromethane at 0℃; for 1h;
Stage #2: (+)-matrine In dichloromethane at 0 - 20℃; for 8h;
85%
(+)-matrine
519-02-8

(+)-matrine

C15H25N3O

C15H25N3O

Conditions
ConditionsYield
With chloro(meso-tetrakis(2,6-dichlorophenyl)porphyrinato)manganese(III); O-(2,4-dinitrophenyl)hydroxylamine In dichloromethane for 24h; Catalytic behavior; Reagent/catalyst; Solvent;89%
With manganese(III) 5,10,15,20-tetrakis-(2,6-dichlorophenyl) porphyrin; O-(2,4-dinitrophenyl)hydroxylamine In dichloromethane at 20℃; for 24h;89%
(+)-matrine
519-02-8

(+)-matrine

(+)-allomatrine
641-39-4

(+)-allomatrine

Conditions
ConditionsYield
With hydrogen; platinum(IV) oxide In acetic acid for 15h; Heating;88%
With hydrogen; platinum(IV) oxide In water at 95 - 98℃; under 760 Torr; for 12h; Isomerization;452 mg
(+)-matrine
519-02-8

(+)-matrine

4-((1R,3aR,10aR,13aS)-decahydro-1H,4H-pyrido[3,2,1-ij][1,6]naphthyridin-1-yl)butyric acid
1345731-45-4

4-((1R,3aR,10aR,13aS)-decahydro-1H,4H-pyrido[3,2,1-ij][1,6]naphthyridin-1-yl)butyric acid

Conditions
ConditionsYield
With water; potassium hydroxide for 10h; Reflux;88%
(+)-matrine
519-02-8

(+)-matrine

(4S,7aS,13aR,13bR)-dodecahydro-1H,5H,8Hdipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridine-10-carbonitrile

(4S,7aS,13aR,13bR)-dodecahydro-1H,5H,8Hdipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridine-10-carbonitrile

Conditions
ConditionsYield
Stage #1: (+)-matrine With bis(triphenylphosphine)iridium(I) carbonyl chloride In toluene at 20℃; for 0.0833333h;
Stage #2: With 1,1,3,3-Tetramethyldisiloxane In toluene at 20℃; for 0.0833333h;
Stage #3: With trimethylsilyl cyanide In toluene at 20℃; for 0.5h;
85%
(+)-matrine
519-02-8

(+)-matrine

C15H22Cl2N2O

C15H22Cl2N2O

Conditions
ConditionsYield
With trichlorophosphate at 100℃; for 16h; Reagent/catalyst; Temperature;85%
4-toluenesulfonyl azide
941-55-9

4-toluenesulfonyl azide

(+)-matrine
519-02-8

(+)-matrine

C22H31N3O2S

C22H31N3O2S

Conditions
ConditionsYield
Stage #1: (+)-matrine With bis(triphenylphosphine)carbonyliridium(I) chloride; 1,1,3,3-Tetramethyldisiloxane In dichloromethane at 20℃; for 0.5h;
Stage #2: 4-toluenesulfonyl azide In dichloromethane at 20℃; for 3h; chemoselective reaction;
81%
methanol
67-56-1

methanol

(+)-matrine
519-02-8

(+)-matrine

matrinic acid methyl ester hydrochloride

matrinic acid methyl ester hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In water at 115℃; for 24h;76%
methanol
67-56-1

methanol

(+)-matrine
519-02-8

(+)-matrine

methyl matrinate dihydrochloride

methyl matrinate dihydrochloride

Conditions
ConditionsYield
With hydrogenchloride In water for 24h; Reflux;76%
Stage #1: (+)-matrine With sodium hydroxide for 9h; Reflux;
Stage #2: With hydrogenchloride pH=5 - 6;
Stage #3: methanol With hydrogenchloride for 2h; Reflux;
aniline
62-53-3

aniline

(+)-matrine
519-02-8

(+)-matrine

(E)-15-(N-phenyl) matrinic imine

(E)-15-(N-phenyl) matrinic imine

Conditions
ConditionsYield
Stage #1: (+)-matrine With trichlorophosphate In dichloromethane at 20 - 60℃;
Stage #2: aniline In dichloromethane at 60℃; for 12h;
73%
C21H36Cl2N5O5P

C21H36Cl2N5O5P

(+)-matrine
519-02-8

(+)-matrine

C30H49Cl2N8O3P

C30H49Cl2N8O3P

Conditions
ConditionsYield
Stage #1: C21H36Cl2N5O5P With trifluoroacetic acid In dichloromethane at 20℃; for 1h;
Stage #2: (+)-matrine With trichlorophosphate In dichloromethane for 27h; Reflux;
71.2%
ortho-anisaldehyde
135-02-4

ortho-anisaldehyde

(+)-matrine
519-02-8

(+)-matrine

14-(2-methoxy)phenylmethylenematrine

14-(2-methoxy)phenylmethylenematrine

Conditions
ConditionsYield
With potassium tert-butylate In tetrahydrofuran for 12h; Reflux;67%
malic acid
617-48-1

malic acid

(+)-matrine
519-02-8

(+)-matrine

matrine malate

matrine malate

Conditions
ConditionsYield
In ethanol for 3h;67%
(+)-matrine
519-02-8

(+)-matrine

14-oxime matrine

14-oxime matrine

Conditions
ConditionsYield
Stage #1: (+)-matrine With sodium hexamethyldisilazane In tetrahydrofuran at 20℃; for 0.5h; Inert atmosphere;
Stage #2: With tert.-butylnitrite In tetrahydrofuran at 20℃; for 2h;
67%
4-dimethylamino-benzaldehyde
100-10-7

4-dimethylamino-benzaldehyde

(+)-matrine
519-02-8

(+)-matrine

14-(4-dimethylamino)phenylmethylenematrine

14-(4-dimethylamino)phenylmethylenematrine

Conditions
ConditionsYield
With potassium tert-butylate In tetrahydrofuran for 12h; Reflux;66%
copper(II) perchlorate hexahydrate

copper(II) perchlorate hexahydrate

(+)-matrine
519-02-8

(+)-matrine

2ClO4(1-)*C30H54CuN4O5(2+)*2ClHO4

2ClO4(1-)*C30H54CuN4O5(2+)*2ClHO4

Conditions
ConditionsYield
In ethanol at 60℃; for 6h;61%
(+)-matrine
519-02-8

(+)-matrine

thiomatrine

thiomatrine

Conditions
ConditionsYield
With Lawessons reagent In toluene at 100℃; for 6h;58%
With Lawessons reagent In toluene at 100℃; for 8h;50%
With Lawessons reagent
2-carbethoxyindole
3770-50-1

2-carbethoxyindole

(+)-matrine
519-02-8

(+)-matrine

C24H29N3O2

C24H29N3O2

Conditions
ConditionsYield
Stage #1: (+)-matrine With lithium diisopropyl amide In tetrahydrofuran at 20℃; for 0.5h; Inert atmosphere; Cooling with ice;
Stage #2: 2-carbethoxyindole In tetrahydrofuran for 3h; Inert atmosphere;
53%
pivalaldehyde
630-19-3

pivalaldehyde

(+)-matrine
519-02-8

(+)-matrine

14-tert-butylmethylenematrine

14-tert-butylmethylenematrine

Conditions
ConditionsYield
With potassium tert-butylate In tetrahydrofuran for 12h; Reflux;53%
(+)-matrine
519-02-8

(+)-matrine

anthranilic acid nitrile
1885-29-6

anthranilic acid nitrile

4-amino-quinolinomatrine

4-amino-quinolinomatrine

Conditions
ConditionsYield
Stage #1: (+)-matrine With trichlorophosphate In dichloromethane at 20 - 60℃;
Stage #2: anthranilic acid nitrile In dichloromethane at 60℃; for 12h;
53%
furfural
98-01-1

furfural

(+)-matrine
519-02-8

(+)-matrine

14-(2-furyl)methylenematrine

14-(2-furyl)methylenematrine

Conditions
ConditionsYield
With potassium tert-butylate In tetrahydrofuran for 12h; Reflux;48%
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