As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch
Cas:5190-68-1
Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
Cas:5190-68-1
Min.Order:0 Metric Ton
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inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so
Cas:5190-68-1
Min.Order:1 Metric Ton
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Type:Lab/Research institutions
inquiryWith our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin
Cas:5190-68-1
Min.Order:1 Kilogram
FOB Price: $100.0 / 150.0
Type:Trading Company
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:5190-68-1
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:5190-68-1
Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiry4-CHLORO-QUINAZOLINE CAS:5190-68-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic inte
Cas:5190-68-1
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:5190-68-1
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryBest quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia
J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:5190-68-1
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiry1)quick response within 12 hours; 2)quality guarantee: all products are strictly tested by our qc, confirmed by qa and approved by third party lab in china, usa, canada, germany, uk, italy, france etc. 3) oem/odm available; 4) rea
Cas:5190-68-1
Min.Order:1 Gram
FOB Price: $4.0
Type:Lab/Research institutions
inquiry4-CHLORO-QUINAZOLINE Chemical Properties Melting point 96-100 °C Boiling point 281.0±13.0 °C(Predicted) density 1.349±0.06 g/cm3(Predicted) storage temp. Inert atmosphere,2-8°C pka 0.83±0.30(Predict
Cas:5190-68-1
Min.Order:1 Gram
FOB Price: $66.0
Type:Lab/Research institutions
inquiryOur company is engaged in customizing the benzene ring and pyridine derivative organic intermediates, and the quantity is flexible according to customer's needs. It mainly provides high-quality intermediates for domestic and foreign pharmaceuti
Cas:5190-68-1
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryWe Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O
High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:Active Pharmaceutical I
ISO/factory/goodqualityAppearance:White to yellow Storage:Dry,cool place Package:drum Application:active pharmaceutical ingredients Transportation:by air/sea/express Port:shenzhen/shanghai
Shanghai Lonwin Chemical company is a subsidiary of Lonwin Industry Group Limited, was established in 2011 and is headquartered in Shanghai, adjacent to China National Convention and Exhibition Center and Hongqiao transportation hub.Lonwinchem is
Cas:5190-68-1
Min.Order:100 Kilogram
FOB Price: $100.0 / 150.0
Type:Other
inquiryhigh purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier
high qualityAppearance:white crystalline powder Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea
Cas:5190-68-1
Min.Order:0
Negotiable
Type:Manufacturers
inquiryOur clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS
Shanghai Finebiotech Co.,Ltd.was established in 2020, which providing professional chemical services. As a customer-oriented company, we have distinguished ourself from others in providing worldwide customers with cost-effective and efficient service
Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as
Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali
Amoychem is committed to providing the top-quality chemical products and services Internationally. We offer our customers with friendly, professional service and reliable, high performance products that have been manufactured according to the accredi
Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present
Factory supply high purity low priceAppearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China
Cas:5190-68-1
Min.Order:0
Negotiable
Type:Trading Company
inquiry4-Chloroquinazoline cas 5190-68-1Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express
factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
4-(methylsulfanyl)quinazoline
4-chloroquinazoline
Conditions | Yield |
---|---|
With sulfuryl dichloride In dichloromethane; acetonitrile at 0℃; for 0.5h; | 99% |
Conditions | Yield |
---|---|
With phosphorus pentachloride; trichlorophosphate for 0.333333h; Heating / reflux; | 93% |
With trichlorophosphate at 100℃; for 4h; | 92% |
With thionyl chloride for 3h; Reflux; | 89.7% |
Conditions | Yield |
---|---|
With thionyl chloride Reflux; | 92.7% |
With thionyl chloride Reflux; | 92.7% |
With thionyl chloride Reflux; | 92.7% |
Conditions | Yield |
---|---|
With 1,2-dichloro-ethane In dimethyl sulfoxide; N,N-dimethyl-formamide Reflux; | 81% |
With N-ethyl-N,N-diisopropylamine; trichlorophosphate for 2h; Heating / reflux; | 60% |
With trichlorophosphate at 115℃; for 8h; | |
With thionyl chloride | |
With trichlorophosphate at 115℃; |
Conditions | Yield |
---|---|
With sulfuryl dichloride In dichloromethane; acetonitrile at 0℃; for 0.5h; | 79% |
C15H11ClN2S
4-chloroquinazoline
Conditions | Yield |
---|---|
With sulfuryl dichloride In dichloromethane; acetonitrile at 0℃; for 0.5h; | 66% |
Conditions | Yield |
---|---|
In toluene | 29% |
In toluene | 29% |
4-Hydroxyquinazoline
phosphorus pentachloride
trichlorophosphate
4-chloroquinazoline
anthranilic acid
formamide
4-chloroquinazoline
Conditions | Yield |
---|---|
Stage #1: anthranilic acid; formamide Cyclization; Stage #2: With trichlorophosphate for 3h; Substitution; Heating; |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 95.4 percent / Heating 2: 54.5 percent / PCl5; POCl3 / 24 h / Heating View Scheme | |
Multi-step reaction with 2 steps 1: Heating 2: phosphorus oxychloride, phosphorus pentachloride / 5.5 h / Heating View Scheme | |
Multi-step reaction with 2 steps 1: 4 h / 120 - 125 °C 2: phosphorus pentachloride; trichlorophosphate / 4 h / 118 - 120 °C View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 90 percent / 0.33 h / 150 °C / MW irradiation 2: 85 percent / phosphoryl chloride / 0.17 h / 100 °C / MW irradiation View Scheme |
anthranilic acid amide
4-chloroquinazoline
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 12 N HCl 2: POCl3 / 90 °C View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 2 h / 170 °C 2: POCl3, dimethylaniline / toluene / 4 h / Heating View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 69 percent / 1.) 120 deg C, 2 h; 2.) 170 deg C, 2 h 2: 78.8 percent / PCl5 / POCl3 / 2 h / Heating View Scheme |
6,7-bis(2-methoxyethoxy)quinazolin-4(3H)-one
4-chloroquinazoline
Conditions | Yield |
---|---|
With trichlorophosphate |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: sulfuric acid / 0.08 h / 100 °C / Microwave irradiation 2: diethylamine; trichlorophosphate / 0.17 h / 100 °C / Microwave irradiation View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: N,N-dimethyl-formamide / 12 h / Reflux 2: triethylamine; trichlorophosphate / toluene / 4 h / Reflux View Scheme | |
Multi-step reaction with 2 steps 2: trichlorophosphate View Scheme | |
Multi-step reaction with 2 steps 1: formic acid / 5 h / 135 °C / Inert atmosphere 2: trichlorophosphate / 8 h / 115 °C View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 10 h / 135 - 140 °C 2: trichlorophosphate / N,N-dimethyl-formamide / 5 h / 70 °C View Scheme |
O-Benzoylhydroxylamine
4-chloroquinazoline
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 5 h / 135 - 145 °C 2: thionyl chloride / N,N-dimethyl-formamide; 1,2-dichloro-ethane / 4.5 h / Reflux View Scheme |
4-chloroquinazoline
ethyl 10-aminoundecanoate
4-(10-(ethoxycarbonyl)decyl-2-amino)quinazoline
Conditions | Yield |
---|---|
With triethylamine In ethanol at 20℃; Substitution; | 99% |
4-chloroquinazoline
N-methyl-N-(1-phenylethyl)amine
Conditions | Yield |
---|---|
With diethylaminomethylpolystyrene; polymer-supported Et3N In N,N-dimethyl-formamide; butan-1-ol at 100℃; for 16h; | 99% |
4-chloroquinazoline
3-chloro-4-fluorophenylamine
N-(3-chloro-4-fluorophenyl)quinazolin-4-amine
Conditions | Yield |
---|---|
In isopropyl alcohol for 2h; Reflux; | 99% |
In isopropyl alcohol for 6h; Reflux; | 91.6% |
4-chloroquinazoline
C13H12BrN3O
Conditions | Yield |
---|---|
In isopropyl alcohol for 2h; Reflux; | 99% |
4-chloroquinazoline
2-<(benzylidene)amino>benzonitrile
Conditions | Yield |
---|---|
In diethyl ether at 35℃; for 2h; | 98% |
In tetrahydrofuran for 3h; Heating; | 75% |
4-chloroquinazoline
(4-methoxyphenyl)(quinazolin-4-yl)methanone
Conditions | Yield |
---|---|
With sodium hydride In tetrahydrofuran for 1h; Heating; | 98% |
4-chloroquinazoline
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide at 40 - 50℃; for 0.5h; | 97.6% |
4-chloroquinazoline
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide at 40 - 50℃; for 0.5h; | 97.4% |
Conditions | Yield |
---|---|
With potassium fluoride In water at 100℃; for 17h; Green chemistry; | 97% |
4-chloroquinazoline
4-methoxy-dibenzofuran-3-ylamine
Conditions | Yield |
---|---|
In isopropyl alcohol for 0.333333h; microwave irradiation; | 96.5% |
Conditions | Yield |
---|---|
In 1,4-dioxane for 3h; Inert atmosphere; Reflux; | 96% |
With potassium fluoride In water at 100℃; for 17h; Green chemistry; | 80% |
With benzene |
4-chloroquinazoline
benzaldehyde
A
4-(benzyloxy)quinazoline
B
phenyl(quinazolin-4-yl)methanone
Conditions | Yield |
---|---|
With 1,3-dimethylbenzimidazolium Iodide; sodium hydride In tetrahydrofuran for 1h; Heating; | A 1% B 96% |
4-chloroquinazoline
methylhydrazine
1-methyl-1-(1-quinazolyl)hydrazine
Conditions | Yield |
---|---|
In dichloromethane at 0 - 20℃; for 3.75h; | 96% |
In dichloromethane | 80% |
Conditions | Yield |
---|---|
In isopropyl alcohol for 6h; Reflux; | 95.8% |
4-chloroquinazoline
2-Fluoroaniline
N-(2-fluorophenyl)quinazolin-4-amine
Conditions | Yield |
---|---|
In isopropyl alcohol for 6h; Reflux; | 95.4% |
4-chloroquinazoline
N-phenyl-hydrazine carboxylic acid tert-butyl ester
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In isopropyl alcohol at 60℃; for 0.5h; Microwave irradiation; | 95.4% |
4-chloroquinazoline
O-potassio-3,3-dimethyl-2-butanone
1-(quinazolin-4-yl)-3,3-dimethyl-2-butanone
Conditions | Yield |
---|---|
With ammonia; potassium amide In diethyl ether for 0.25h; | 95% |
Conditions | Yield |
---|---|
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); caesium carbonate In N,N-dimethyl-formamide at 20℃; for 3h; Sonogashira Cross-Coupling; Inert atmosphere; | 95% |
4-chloroquinazoline
1-phenyl-2,2,2-trifluoromethylethanol
Conditions | Yield |
---|---|
With caesium carbonate In acetonitrile at 20℃; for 2h; Temperature; Time; Solvent; Reagent/catalyst; Inert atmosphere; Reflux; | 95% |
Conditions | Yield |
---|---|
In isopropyl alcohol for 5h; Reflux; | 95% |
4-chloroquinazoline
1-naphthalene methanol
4-(1-naphthylmethyloxy)quinazoline
Conditions | Yield |
---|---|
With sodium hydride Ambient temperature; | 94% |
Conditions | Yield |
---|---|
Stage #1: 4-chloroquinazoline With lithium n-butanetelluroate In tetrahydrofuran at 20℃; for 0.166667h; Stage #2: With n-butyllithium In tetrahydrofuran at -78℃; Stage #3: With pivalaldehyde In tetrahydrofuran at -78 - 20℃; | 94% |
Conditions | Yield |
---|---|
With hydrogenchloride In water Reflux; | 94% |
With hydrogenchloride In water Reflux; | 94% |
In N,N-dimethyl-formamide Microwave; | |
With triethylamine In isopropyl alcohol at 80℃; |
Conditions | Yield |
---|---|
In isopropyl alcohol for 6h; Reflux; | 93.3% |
In isopropyl alcohol Reflux; | 68% |
In isopropyl alcohol Heating; |
furfural
4-chloroquinazoline
A
4-(1-naphthoyl)quinazoline
B
furan-2-yl-quinazolin-4-yl-methanone
Conditions | Yield |
---|---|
With 1,3-dimethylbenzimidazolium Iodide; sodium hydride In N,N-dimethyl-formamide at 80℃; for 0.0833333h; | A 23% B 93% |
4-chloroquinazoline
2-chloro-benzaldehyde
(2-chloro-phenyl)-quinazolin-4-yl-methanone
Conditions | Yield |
---|---|
With 1,3-dimethylbenzimidazolium Iodide; sodium hydride In N,N-dimethyl-formamide for 0.166667h; Ambient temperature; | 93% |
Conditions | Yield |
---|---|
With potassium phosphate; dichloro(1,5-cyclooctadiene)palladium(II); 2-(diphenylphosphino)-dimesitylborylbenzene In toluene at 100℃; for 20h; Suzuki-Miyaura Coupling; Schlenk technique; Glovebox; Inert atmosphere; | 93% |
4-chloroquinazoline
2,2-difluoro-1-phenyl-ethanol
Conditions | Yield |
---|---|
With caesium carbonate In acetonitrile for 2.5h; Inert atmosphere; Reflux; | 93% |
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