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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

3-Chloro-4-fluoroaniline Manufacturer/High quality/Best price/In stock

Cas:367-21-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 3-Chloro-4-Fluoroaniline supplier in China

Cas:367-21-5

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Henan Allgreen Chemical Co.,Ltd

Good quality Good price Promptly delivery Appearance:white powder Storage:dry dondition Package:According to the demand of customer Application:intermediate Transportation:According to the demand of customer Port:shanghai

367-21-53-Chloro-4-fluoroaniline

Cas:367-21-5

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 3-chloro-4-fluoroaniline

Cas:367-21-5

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price OLED 99% 367-21-5 3-Chloro-4-fluoroaniline Manufacturer

Cas:367-21-5

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

3-Chloro-4-fluoroaniline

Cas:367-21-5

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

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ANQING CHICO PHARMACEUTICAL CO.,LTD.

High quality. Factory supply. In stock. Best price.1.Quick response within 24 hours;2.Best quality in your requirement;?3.We pay more attention on delivery time, and usually ship on time;4.Under the premise of safety and effectiveness, we can produce

3-Chloro-4-fluoroaniline

Cas:367-21-5

Min.Order:0

Negotiable

Type:Trading Company

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

3-Chloro-4-fluoroaniline

Cas:367-21-5

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

Hebei Yanxi Chemical Co., Ltd. is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low car

3-chloro-4-fluoroaniline

Cas:367-21-5

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Trading Company

inquiry

Hubei DiBo chemical co., LTD

Name:3-Chloro-4-fluoroaniline CAS:367-21-5 Grade:For chemical industry, scientific research and export Product Quality 12 years of chemical raw materials Mature operation of the industry System stability Data storage Security without vulnerab

3-Chloro-4-fluoroaniline Manufacturer/High quality/Best price/In stock

Cas:367-21-5

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

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Hebei Nengqian Chemical Import and Export Co., LTD

3-Chloro-4-fluoroaniline CAS No.367-21-5 White crystalline powder 99% 3-Chloro-4-fluoroaniline CAS No.367-21-5 Product name 3-Chloro-4-fluoroaniline Synonyms 3-Chloro-4-fluorobenzenamine CAS No. 367

High Quality 3-Chloro-4-Fluoroaniline CAS: 367-21-5

Cas:367-21-5

Min.Order:1 Kilogram

FOB Price: $10.0 / 20.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company engages in Sodium Tripolyphosphate (STPP) and Sodium Hexametabphosphate (SHMP) production; development of noble metal catalysts, synthesis of electronic chemical materials and general chemicals Imp&Exp trading business. The company

TIANFU-CHEM - 3-Chloro-4-fluoroaniline

Cas:367-21-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 367-21-5 with best quality

Cas:367-21-5

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:white or off-white powder Storage:Store in sealed containers

Intermediate factory 3-Chloro-4-fluoroaniline 367-21-5

Cas:367-21-5

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

3-Chloro-4-fluoroaniline 367-21-5

Cas:367-21-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

3-Chloro-4-fluoroaniline CAS:367-21-5

Cas:367-21-5

Min.Order:1 Kilogram

FOB Price: $45.0 / 50.2

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

3-Chloro-4-fluoroaniline CAS:367-21-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic in

3-Chloro-4-fluoroaniline CAS:367-21-5

Cas:367-21-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

3-Chloro-4-fluoroaniline

Cas:367-21-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

3-Chloro-4-fluoroaniline/ LIDE PHARMA- Factory supply / Best price

Cas:367-21-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:367-21-5

Cas:367-21-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

3-CHLORO-4-FLUOROANILINE A

Cas:367-21-5

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

3-Chloro-4-Fluoroaniline

Cas:367-21-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

3-Chloro-4-fluoro aniline

Cas:367-21-5

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

cas 367-21-5 cas 367-21-5 3-Chloro-4-fluoroaniline

Cas:367-21-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

3-CHLORO-4-FLUOROANILINE

Cas:367-21-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

3-Chloro-4-fluoroaniline

Cas:367-21-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Miheng Trading Co., Ltd.

3-Chloro-4-fluoroaniline CAS 367-21-5 Our advantage 1.Top quality: Using high quality material and establishing a strict quality control system,assigning specific persons in charge of each part of production,from raw material purchase to asse

3-Chloro-4-fluoroaniline CAS 367-21-5

Cas:367-21-5

Min.Order:1 Kilogram

FOB Price: $10.0 / 50.0

Type:Trading Company

inquiry

ACHIEVER SYSTEAM BIOCHEM CO., LTD.

We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to provide excellence in researching, manufacturing and drug discovery process. Our research team of scientists co

3-Chloro-4-fluoroaniline

Cas:367-21-5

Min.Order:100 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Hefei Zhaobo Technology Co., Ltd.

3-Chloro-4-fluoroaniline CAS 367-21-5 Purity: 99% Min Application: Intermediates Appearance: Powder Package: Bag Delivery: 3-5days Our Advantage & Service 1.Top quality: Using high quality material and establishing a strict quality c

3-Chloro-4-fluoroaniline CAS 367-21-5

Cas:367-21-5

Min.Order:1 Kilogram

FOB Price: $10.0 / 50.0

Type:Trading Company

inquiry

Synthetic route

3-chloro-4-fluoronitrobenzene
350-30-1

3-chloro-4-fluoronitrobenzene

3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

Conditions
ConditionsYield
With hydrogen In ethanol; water at 25℃; under 760.051 Torr; for 3h; Autoclave;99.9%
With sodium tetrahydroborate; cyclohexanediamine-Pd-β-cyclodextrin In water at 20℃; for 3h; Sealed tube;96%
With hydrazine hydrate In ethanol at 100℃; under 760.051 Torr; for 8h; Time; Sealed tube; chemoselective reaction;94.7%
C14H11ClFNO2

C14H11ClFNO2

3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

Conditions
ConditionsYield
With methanol; sodium tetrahydroborate; nickel(II) chloride hexahydrate at 20℃; for 0.25h; chemoselective reaction;86%
(3-chloro-4-fluoro-phenyl)-carbamic acid tert-butyl ester
119951-96-1

(3-chloro-4-fluoro-phenyl)-carbamic acid tert-butyl ester

3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

Conditions
ConditionsYield
With methanol; oxalyl dichloride at 20℃; for 2h;80%
3-Chloronitrobenzene
121-73-3

3-Chloronitrobenzene

A

3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

B

3-chloro-aniline
108-42-9

3-chloro-aniline

Conditions
ConditionsYield
With Piperonyl butoxide; hydrogen fluoride Yields of byproduct given;A 34%
B n/a
1-(3-Chloro-4-fluoro-phenyl)-ethanone oxime

1-(3-Chloro-4-fluoro-phenyl)-ethanone oxime

3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

Conditions
ConditionsYield
(i) PCl5, (ii) aq. HCl; Multistep reaction;
4-Fluoronitrobenzene
350-46-9

4-Fluoronitrobenzene

3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: iron-powder / Einleiten von Chlor
2: titanium (III)-chloride; water
View Scheme
Multi-step reaction with 2 steps
1: Cl2, FeCl3
2: Fe, aq. NH4Cl
View Scheme
3-chloro-aniline
108-42-9

3-chloro-aniline

3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: hydrogenchloride; sodium nitrite / water / 0.5 h
2: trifluoromethan; fluorosulfonyl fluoride / 70 °C
3: hydrogenchloride / water / 2 h / 50 °C
View Scheme
4-fluoro-3-chloronitrosoaniline

4-fluoro-3-chloronitrosoaniline

3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

Conditions
ConditionsYield
With hydrogenchloride In water at 50℃; for 2h;
3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

diethyl 2-ethoxymethylenemalonate
87-13-8

diethyl 2-ethoxymethylenemalonate

diethyl 2-[(3-chloro-4-fluorophenylamino)methylene]malonate
70032-30-3

diethyl 2-[(3-chloro-4-fluorophenylamino)methylene]malonate

Conditions
ConditionsYield
at 120 - 130℃; for 2h;100%
for 0.0333333h; Gould-Jacob reaction; Irradiation;99%
at 110℃; for 1h; Microwave irradiation;99%
3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

(3-chloro-4-fluoro-phenyl)-carbamic acid tert-butyl ester
119951-96-1

(3-chloro-4-fluoro-phenyl)-carbamic acid tert-butyl ester

Conditions
ConditionsYield
Stage #1: 3-chloro-4-fluorophenylamine With triethylamine In tetrahydrofuran; water at 20℃; for 0.0833333h;
Stage #2: di-tert-butyl dicarbonate In tetrahydrofuran; water at 0 - 20℃; for 6h;
100%
With 1-butyl-3-methylimidazolium trifluoromethanesulfonimide at 30 - 35℃; for 0.25h; neat (no solvent); chemoselective reaction;95%
In water at 30 - 35℃; for 6h;92%
3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

4-chloro-7-fluoro-6-nitroquinazoline
162012-70-6

4-chloro-7-fluoro-6-nitroquinazoline

N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine
162012-67-1

N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine

Conditions
ConditionsYield
In isopropyl alcohol for 4h; Product distribution / selectivity; Reflux;100%
With triethylamine In isopropyl alcohol for 1.5h;100%
In isopropyl alcohol at 20℃; for 24h; Inert atmosphere;99%
3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

4-chloro-6-nitro-7-trifluoromethoxyquinoline-3-carbonitrile
492456-55-0

4-chloro-6-nitro-7-trifluoromethoxyquinoline-3-carbonitrile

4-(3-chloro-4-fluorophenylamino)-6-nitro-7-trifluoromethoxyquinoline-3-carbonitrile
492456-57-2

4-(3-chloro-4-fluorophenylamino)-6-nitro-7-trifluoromethoxyquinoline-3-carbonitrile

Conditions
ConditionsYield
In isopropyl alcohol for 3.5h; Heating;100%
In ethanol for 12h; Heating;
3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

6-bromo-4-chloro-3-quinolinecarbonitrile
364793-54-4

6-bromo-4-chloro-3-quinolinecarbonitrile

6-bromo-N-(3-chloro-4-fluoro-phenyl)-quinoline-3-carbnitrile-4-amine
915369-04-9

6-bromo-N-(3-chloro-4-fluoro-phenyl)-quinoline-3-carbnitrile-4-amine

Conditions
ConditionsYield
In 1,4-dioxane at 90℃; for 2h;100%
In 1,4-dioxane at 90℃; for 2h;100%
In 2-ethoxy-ethanol at 135℃; for 2.5h; Heating / reflux;56%
With aniline In isopropyl alcohol at 80℃; for 24h;38.8%
In ethanol for 12h; Heating;
3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

2-chloro-5-methoxyquinoline
160893-07-2

2-chloro-5-methoxyquinoline

N-(3-chloro-4-fluorophenyl)-5-methoxyquinolin-2-amine

N-(3-chloro-4-fluorophenyl)-5-methoxyquinolin-2-amine

Conditions
ConditionsYield
In neat (no solvent) at 160℃;100%
1-methyl-piperazine
109-01-3

1-methyl-piperazine

3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

bis(trichloromethyl) carbonate
32315-10-9

bis(trichloromethyl) carbonate

N-(3-chloro-4-fluorophenyl)-4-methylpiperazine-1-carboxamide

N-(3-chloro-4-fluorophenyl)-4-methylpiperazine-1-carboxamide

Conditions
ConditionsYield
Stage #1: 3-chloro-4-fluorophenylamine; bis(trichloromethyl) carbonate With N-ethyl-N,N-diisopropylamine In dichloromethane at 0℃;
Stage #2: 1-methyl-piperazine In dichloromethane at 20℃; for 3h;
100%
3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

2,6-dichloro-4-(pyrrolidin-1-yl)pyrido[3,4-d]pyrimidine

2,6-dichloro-4-(pyrrolidin-1-yl)pyrido[3,4-d]pyrimidine

6-chloro-N-(3-chloro-4-fluorophenyl)-4-(pyrrolidin-1-yl)pyrido[3,4-d]pyrimidin-2-amine

6-chloro-N-(3-chloro-4-fluorophenyl)-4-(pyrrolidin-1-yl)pyrido[3,4-d]pyrimidin-2-amine

Conditions
ConditionsYield
With toluene-4-sulfonic acid In iso-butanol Reflux; Inert atmosphere;100%
3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

chloroacetyl chloride
79-04-9

chloroacetyl chloride

N-(2-chloroacetyl)-3-chloro-4-fluoroaniline
96980-64-2

N-(2-chloroacetyl)-3-chloro-4-fluoroaniline

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 25℃;99.3%
With triethylamine In dichloromethane at 0 - 25℃;99.3%
With pyridine In benzene for 1h; Ambient temperature;90%
3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

6-acetoxy-4-chloro-7-methoxyquinazoline
230955-75-6

6-acetoxy-4-chloro-7-methoxyquinazoline

4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate
788136-89-0

4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate

Conditions
ConditionsYield
In isopropyl alcohol for 2h; Inert atmosphere; Reflux;99%
With gold(I) chloride In methanol at 65℃; Reagent/catalyst; Temperature; Concentration;93.4%
In isopropyl alcohol for 2h; Reflux;92.5%
3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

4-chloro-7-methoxy-6-(3-morpholinopropoxy)quinazoline
199327-59-8

4-chloro-7-methoxy-6-(3-morpholinopropoxy)quinazoline

gefitinib
184475-35-2

gefitinib

Conditions
ConditionsYield
With potassium hydroxide In isopropyl alcohol at 20℃;99%
In isopropyl alcohol at 80℃; for 0.533333h; Microwave irradiation;92%
With N,N,N,N,-tetramethylethylenediamine; nickel dichloride In tetrahydrofuran at 50℃; for 0.333333h; Concentration; Temperature; Reagent/catalyst;92.5%
C11H3ClF3N3O2

C11H3ClF3N3O2

3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

C17H7ClF4N4O2

C17H7ClF4N4O2

Conditions
ConditionsYield
In ethanol99%
3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

4-chloro-7-methoxy-6-nitro-quinoline-3-carbonitrile
214470-33-4

4-chloro-7-methoxy-6-nitro-quinoline-3-carbonitrile

4-(3-Chloro-4-fluoro-phenylamino)-7-methoxy-6-nitro-quinoline-3-carbonitrile
214485-59-3

4-(3-Chloro-4-fluoro-phenylamino)-7-methoxy-6-nitro-quinoline-3-carbonitrile

Conditions
ConditionsYield
Stage #1: 3-chloro-4-fluorophenylamine; 4-chloro-7-methoxy-6-nitro-quinoline-3-carbonitrile In isopropyl alcohol at 20℃; for 22h; Heating / reflux;
Stage #2: With sodium hydrogencarbonate In water; ethyl acetate
99%
In methanol; 2-methoxy-ethanol; ethyl acetate
In methanol; 2-methoxy-ethanol; ethyl acetate
4-chloro-7-ethoxy-6-nitroquinazoline
936954-10-8

4-chloro-7-ethoxy-6-nitroquinazoline

3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

N-(3-chloro-4-fluorophenyl)-7-ethoxy-6-nitroquinazoline-4-amine
1360430-70-1

N-(3-chloro-4-fluorophenyl)-7-ethoxy-6-nitroquinazoline-4-amine

Conditions
ConditionsYield
With hydrogenchloride In water; isopropyl alcohol Reflux;99%
In dichloromethane; isopropyl alcohol at 20℃;93%
In dichloromethane; isopropyl alcohol at 20℃;93%
In isopropyl alcohol for 1h; Reflux;89%
With toluene-4-sulfonic acid In isopropyl alcohol at 75℃; for 5h;76%
4-chloroquinazoline
5190-68-1

4-chloroquinazoline

3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

N-(3-chloro-4-fluorophenyl)quinazolin-4-amine
457932-97-7

N-(3-chloro-4-fluorophenyl)quinazolin-4-amine

Conditions
ConditionsYield
In isopropyl alcohol for 2h; Reflux;99%
In isopropyl alcohol for 6h; Reflux;91.6%
3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

C15H13O4Pol

C15H13O4Pol

C21H18ClFNO2Pol

C21H18ClFNO2Pol

Conditions
ConditionsYield
Stage #1: 3-chloro-4-fluorophenylamine; C15H13O4Pol With acetic acid In dichloromethane at 20℃; for 2h; not specified; Schlenk technique; Molecular sieve;
Stage #2: With sodium tris(acetoxy)borohydride at 20℃; for 17h; not specified; Schlenk technique;
99%
3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

4-chloro-7-(3-chloropropoxy)-6-nitroquinoline-3-carbonitrile
501684-28-2

4-chloro-7-(3-chloropropoxy)-6-nitroquinoline-3-carbonitrile

4-(3-chloro-4-fluoro-phenylamino)-7-(3-chloro-propoxy)-6-nitro-quinoline-3-carbonitrile
501684-29-3

4-(3-chloro-4-fluoro-phenylamino)-7-(3-chloro-propoxy)-6-nitro-quinoline-3-carbonitrile

Conditions
ConditionsYield
In isopropyl alcohol Heating;98%
3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

4-chloro-1H-pyrrolo[2,3-d]pyrimidine
3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

(3-chloro-4-fluoro-phenyl)-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine
346600-33-7

(3-chloro-4-fluoro-phenyl)-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine

Conditions
ConditionsYield
With silver trifluoromethanesulfonate In N,N-dimethyl-formamide at 90℃;98%
3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

ortho-toluoyl chloride
933-88-0

ortho-toluoyl chloride

N-(3-chloro-4-fluorophenyl)-2-methylbenzamide

N-(3-chloro-4-fluorophenyl)-2-methylbenzamide

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃;98%
5-amino-4,6-dichloro-2-methylpyrimidine
39906-04-2

5-amino-4,6-dichloro-2-methylpyrimidine

3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

6-chloro-N4-(3-chloro-4-fluorophenyl)-2-methylpyrimidine-4,5-diamine

6-chloro-N4-(3-chloro-4-fluorophenyl)-2-methylpyrimidine-4,5-diamine

Conditions
ConditionsYield
With hydrogenchloride In ethanol; water at 20℃; for 16h; Reflux;98%
3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

7-chloro-6-nitro-4(3H)-quinazolinone
53449-14-2

7-chloro-6-nitro-4(3H)-quinazolinone

4-((3-chloro-4-fluorophenyl)amino)-6-nitro-7-chloroquinazoline
179552-73-9

4-((3-chloro-4-fluorophenyl)amino)-6-nitro-7-chloroquinazoline

Conditions
ConditionsYield
Stage #1: 7-chloro-6-nitro-4(3H)-quinazolinone With thionyl chloride In N,N-dimethyl-formamide for 3h; Reflux;
Stage #2: 3-chloro-4-fluorophenylamine In 1,4-dioxane; N,N-dimethyl-formamide at 90℃; for 1h;
98%
Stage #1: 7-chloro-6-nitro-4(3H)-quinazolinone With trichlorophosphate In acetonitrile at 80℃; for 5h;
Stage #2: 3-chloro-4-fluorophenylamine In 1,4-dioxane; acetonitrile for 1h;
70%
3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

N-(3-chloro-4-fluoro-phenyl)-formamide
770-22-9

N-(3-chloro-4-fluoro-phenyl)-formamide

Conditions
ConditionsYield
With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide In ethyl acetate at 80℃; for 5.5h; Concentration; Inert atmosphere;98%
3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

Propiolic acid
471-25-0

Propiolic acid

N-(3-chloro-4-fluorophenyl)prop-2-ynamide

N-(3-chloro-4-fluorophenyl)prop-2-ynamide

Conditions
ConditionsYield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 5℃; for 1h;98%
With dmap; dicyclohexyl-carbodiimide In dichloromethane at -20 - 20℃; for 12h;
formic acid
64-18-6

formic acid

3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

N-(3-chloro-4-fluoro-phenyl)-formamide
770-22-9

N-(3-chloro-4-fluoro-phenyl)-formamide

Conditions
ConditionsYield
at 80℃; for 3.5h;97.7%
for 16h; Reflux;93%
With zinc(II) chloride at 70℃; for 1.33333h; neat (no solvent);92%
3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

N,N-dimethyl-formamide dimethyl acetal
4637-24-5

N,N-dimethyl-formamide dimethyl acetal

N'-(3-chloro-4-fluorophenyl)-N,N-dimethylmethanimidamide

N'-(3-chloro-4-fluorophenyl)-N,N-dimethylmethanimidamide

Conditions
ConditionsYield
With acetic anhydride In toluene at 105 - 110℃; for 3h; Time; Reagent/catalyst;97.4%
3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

isopropyl α-methyl α-diazoacetate
1007586-71-1

isopropyl α-methyl α-diazoacetate

(R)-isopropyl 2-(3-chloro-4-fluorophenylamino)propionate
62836-63-9

(R)-isopropyl 2-(3-chloro-4-fluorophenylamino)propionate

Conditions
ConditionsYield
With tetrakis(actonitrile)copper(I) hexafluorophosphate; C35H30N2O2; sodium tetrakis[(3,5-di-trifluoromethyl)phenyl]borate In dichloromethane at 25℃; for 2h; Inert atmosphere; optical yield given as %ee; enantioselective reaction;97%
3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

2-amino-5-hydroxy-4-methoxybenzonitrile

2-amino-5-hydroxy-4-methoxybenzonitrile

N,N-dimethyl-formamide dimethyl acetal
4637-24-5

N,N-dimethyl-formamide dimethyl acetal

4-(3-chloro-4-fluorophenylamino)-6-hydroxy-7-methoxyquinazoline
184475-71-6

4-(3-chloro-4-fluorophenylamino)-6-hydroxy-7-methoxyquinazoline

Conditions
ConditionsYield
With acetic acid In toluene at 65℃; for 7h; Solvent; Temperature; Concentration; Reagent/catalyst; Inert atmosphere;97%
3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

benzyl alcohol
100-51-6

benzyl alcohol

N-(3-chloro-4-fluorophenyl)-benzenemethanamine
131776-32-4

N-(3-chloro-4-fluorophenyl)-benzenemethanamine

Conditions
ConditionsYield
With palladium nanoparticles embedded in the solid matrix of tetrabutylammonium bromide synthetized in supercritical carbon dioxide at 140℃; Sealed tube; Inert atmosphere; Green chemistry;97%
4-chloro-6-iodoquinazoline
98556-31-1

4-chloro-6-iodoquinazoline

3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

4-((3-chloro-4-fluorophenyl)amino)-6-iodoquinazoline
578737-95-8

4-((3-chloro-4-fluorophenyl)amino)-6-iodoquinazoline

Conditions
ConditionsYield
In isopropyl alcohol at 80℃; for 2h;96%
In isopropyl alcohol at 80℃; for 2h;96.3%
With triethylamine In isopropyl alcohol at 20℃; for 9h; Reflux;95%
In tetrahydrofuran for 1h; Reflux;60%
In isopropyl alcohol
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