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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

Haloperidol Manufacturer/High quality/Best price/In stock

Cas:52-86-8

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C

Haloperidol manufacturer with low price

Cas:52-86-8

Min.Order:1 Gram

Negotiable

Type:Manufacturers

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Henan Allgreen Chemical Co.,Ltd

good quality Appearance:white powder Storage:cold storage Package:meet the demand of customer Application:diagnostic reagent Transportation:by sea or by air Port:Shanghai, Qingdao Port

HALOPERIDOL

Cas:52-86-8

Min.Order:1 Gram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Haloperidol

Cas:52-86-8

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price API 99% Haloperidol 52-86-8 GMP Manufacturer

Cas:52-86-8

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

High purity supply Haloperidol

Cas:52-86-8

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Haloperidol

Cas:52-86-8

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hubei DiBo chemical co., LTD

Name: Haloperidol Synonyms: haloperidol; haloperidol; haloperidol; 1-(4-fluorophenyl) -4-[4-(4-chlorophenyl) -4-hydroxy-1-piperidinyl]-1-butanone; iohexol impurity J; haloperidol; haloperidol; haloperidol; methanol test standard (halop

Haloperidol Manufacturer/supplier in China/High quality

Cas:52-86-8

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

Haloperidol

Cas:52-86-8

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Discount priceCAS 52-86-8 with best price

Cas:52-86-8

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Haloperidol/ LIDE PHARMA- Factory supply / Best price

Cas:52-86-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Henan Sinotech Import&Export Corporation

Product Name: Haloperidol Synonyms: 1-(3-p-Fluorobenzoylpropyl)-4-p-chlorophenyl-4-hydroxypiperidine;1-Butanone, 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-;1-butanone,4-(4-(4

Haloperidol

Cas:52-86-8

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Hubei Langyou International Trading Co., Ltd

Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best s

99% Haloperidol 52-86-8 For Antipsychotic

Cas:52-86-8

Min.Order:10 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1-Butanone,4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)- 52-86-8

Cas:52-86-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

Haloperidol CAS: 52-86-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates,

Haloperidol CAS: 52-86-8

Cas:52-86-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Haloperidol

Cas:52-86-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

1-Butanone,4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-

Cas:52-86-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Shanghai Terui OP New Material Technology Co., Ltd.

We have overseas warehouses in California, New Laredo Mexico, Vancouver Canada, Amsterdam Netherlands, and Melbourne Australia. Overseas warehouses can provide some of the best-selling products. We look forward to the cooperation of local powerful

Top Quality Safe Fast Shipping Free Customs Haloperidol CAS 52-86-8

Cas:52-86-8

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

Haloperidol

Cas:52-86-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We have s

52-86-8 Haloperidol

Cas:52-86-8

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Haloperidol

Cas:52-86-8

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Haloperidol

Cas:52-86-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hefei Zhaobo Technology Co., Ltd.

Haloperidol CAS 52-86-8 Purity: 99% Min Application: Intermediates Appearance: Powder Package: Bag Delivery: 3-5days Our Advantage & Service 1.Top quality: Using high quality material and establishing a strict quality control system,

Haloperidol CAS 52-86-8

Cas:52-86-8

Min.Order:1 Kilogram

FOB Price: $10.0 / 50.0

Type:Trading Company

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Wuhan Xinhao Biotechnology Co., Ltd.

Our Strengths 1.Place of Origin China with Super quality by reasonable price. 2.Fast delivery by safe express way to all the country. 3.Has a number of highly qualified engineers and experts to provide guidance for reagents. 4.When you meet problems

High Purity Haloperidol supplier in China CAS NO. 52-86-8

Cas:52-86-8

Min.Order:1 Kilogram

FOB Price: $10.0 / 20.0

Type:Trading Company

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Haloperidol

Cas:52-86-8

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Hangzhou Lingrui Chemical Co.,Ltd.

HaloperidolAppearance:white powder Storage:Keep away of light, cool place Package:according to customers' requirements Application:pharmaceutical intermediates Transportation:By air(EMS or EUB or FedEx or TNT ect...) or by sea(FOB or CIF or CNF ect..

Haloperidol

Cas:52-86-8

Min.Order:1 Gram

Negotiable

Type:Other

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HANGZHOU YUNUO CHEMICAL CO.,LTD

superior quality Appearance:White Crystalline Powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:Antidyskinetic; antipsychotic Transportation:

Haloperidol

Cas:52-86-8

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

Haloperidol

Cas:52-86-8

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after the dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available &diam

Haloperidol CAS52-86-8

Cas:52-86-8

Min.Order:1 Kilogram

FOB Price: $7.0 / 10.0

Type:Trading Company

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Best OfferHaloperidol

Cas:52-86-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

4-(4-chlorophenyl)-1-<4-(4-nitrophenyl)-4-oxobutyl>-4-piperidinol
150717-69-4

4-(4-chlorophenyl)-1-<4-(4-nitrophenyl)-4-oxobutyl>-4-piperidinol

haloperidol
52-86-8

haloperidol

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In dimethyl sulfoxide at 160℃; for 0.166667h; Inert atmosphere; Microwave irradiation; Anhydrous conditions;99%
With hydrogen fluoride; potassium oxalate; potassium carbonate; [2.2.2]cryptande65%
With hydrogen fluoride; potassium oxalate; potassium carbonate; [2.2.2]cryptande In dimethyl sulfoxide at 160℃; for 0.333333h;60%
4-(4-chlorophenyl)-4-hydroxypiperidine
39512-49-7

4-(4-chlorophenyl)-4-hydroxypiperidine

4-(4-fluorophenyl)-4-oxo-n-butyl chloride
3874-54-2

4-(4-fluorophenyl)-4-oxo-n-butyl chloride

haloperidol
52-86-8

haloperidol

Conditions
ConditionsYield
With potassium carbonate; potassium iodide In acetonitrile at 75℃; for 24h; Temperature;88%
With potassium iodide In toluene for 45h; Reflux;85%
With potassium iodide In toluene at 130℃; for 45h; Sealed tube;79%
4-<4-(4-chlorophenyl)-4-hydroxypiperidino>-1,1-ethylenedioxy-1-(4-fluorophenyl)butane
56660-99-2

4-<4-(4-chlorophenyl)-4-hydroxypiperidino>-1,1-ethylenedioxy-1-(4-fluorophenyl)butane

haloperidol
52-86-8

haloperidol

Conditions
ConditionsYield
With hydrogenchloride In methanol for 6h; Heating;65%
With hydrogenchloride In methanol for 2h; Heating;65%
4-fluorophenyl trifluoromethanesulfonate
132993-23-8

4-fluorophenyl trifluoromethanesulfonate

4-(4-chlorophenyl)-1-(4-hydroxybutyl)piperidin-4-ol

4-(4-chlorophenyl)-1-(4-hydroxybutyl)piperidin-4-ol

haloperidol
52-86-8

haloperidol

Conditions
ConditionsYield
With 2,2,6,6-tetramethyl-piperidine; bis(1,5-cyclooctadiene)nickel (0); acetone; [2-((diphenylphospino)methyl)-2-methyl-1,3-propanediyl]bis[diphenylphosphine] In toluene at 130℃; for 20h; Inert atmosphere;37%
Chlorohaloperidol
59995-68-5

Chlorohaloperidol

haloperidol
52-86-8

haloperidol

Conditions
ConditionsYield
With hydrogen fluoride; tetra(n-butyl)ammonium hydroxide
4-(4-chlorophenyl)-4-hydroxypiperidine
39512-49-7

4-(4-chlorophenyl)-4-hydroxypiperidine

haloperidol
52-86-8

haloperidol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 78 percent / acetic acid; NaCNBH3 / methanol / 30 h / 20 °C
2: 65 percent / conc. HCl / methanol / 2 h / Heating
View Scheme
Multi-step reaction with 2 steps
1: K2CO3, KI / dimethylformamide / 17.5 h / 100 °C
2: 65 percent / conc. HCl / methanol / 6 h / Heating
View Scheme
Multi-step reaction with 2 steps
1: potassium iodide / toluene / 48 h / Reflux; Inert atmosphere
2: bis(1,5-cyclooctadiene)nickel (0); [2-((diphenylphospino)methyl)-2-methyl-1,3-propanediyl]bis[diphenylphosphine]; acetone; 2,2,6,6-tetramethyl-piperidine / toluene / 20 h / 130 °C / Inert atmosphere
View Scheme
methyl 3-(4-fluorobenzoyl)-propionate
39560-31-1

methyl 3-(4-fluorobenzoyl)-propionate

haloperidol
52-86-8

haloperidol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 83 percent / p-TsOH / benzene / 20 h / Heating
2: 93 percent / DIBAL-H / CH2Cl2; tetrahydrofuran / 1 h / -78 °C
3: 78 percent / acetic acid; NaCNBH3 / methanol / 30 h / 20 °C
4: 65 percent / conc. HCl / methanol / 2 h / Heating
View Scheme
3-[2-(4-fluorophenyl)-[1,3]dioxolan-2-yl]propionaldehyde
847025-06-3

3-[2-(4-fluorophenyl)-[1,3]dioxolan-2-yl]propionaldehyde

haloperidol
52-86-8

haloperidol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 78 percent / acetic acid; NaCNBH3 / methanol / 30 h / 20 °C
2: 65 percent / conc. HCl / methanol / 2 h / Heating
View Scheme
3-[2-(4-fluorophenyl)-[1,3]dioxolan-2-yl]propionic acid methyl ester
847025-05-2

3-[2-(4-fluorophenyl)-[1,3]dioxolan-2-yl]propionic acid methyl ester

haloperidol
52-86-8

haloperidol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 93 percent / DIBAL-H / CH2Cl2; tetrahydrofuran / 1 h / -78 °C
2: 78 percent / acetic acid; NaCNBH3 / methanol / 30 h / 20 °C
3: 65 percent / conc. HCl / methanol / 2 h / Heating
View Scheme
(4-aminophenyl)(cyclopropyl)methanone
57189-90-9

(4-aminophenyl)(cyclopropyl)methanone

haloperidol
52-86-8

haloperidol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 1) HBF4, NaNO2, 2) Cu, NaNO2 / 1) H2O, 30 min, 2) H2O, 1 h
2: 75 percent / conc. HCl / methanol / 0.5 h / 120 °C
3: 31 percent / KI / toluene / 100 - 110 °C
4: 60 percent / HF, potassium carbonate, potassium oxalate, kryptofix 222 / dimethylsulfoxide / 0.33 h / 160 °C
View Scheme
1-(4-acetylaminophenyl)-4-chloro-1-butanone
56924-11-9

1-(4-acetylaminophenyl)-4-chloro-1-butanone

haloperidol
52-86-8

haloperidol

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 90 percent / 4 M NaOH / ethanol / 2 h / Heating
2: 1) HBF4, NaNO2, 2) Cu, NaNO2 / 1) H2O, 30 min, 2) H2O, 1 h
3: 75 percent / conc. HCl / methanol / 0.5 h / 120 °C
4: 31 percent / KI / toluene / 100 - 110 °C
5: 60 percent / HF, potassium carbonate, potassium oxalate, kryptofix 222 / dimethylsulfoxide / 0.33 h / 160 °C
View Scheme
Acetanilid
103-84-4

Acetanilid

haloperidol
52-86-8

haloperidol

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 20 percent / AlCl3 / CS2 / room temperature, 30 min; 60 deg C, 2 h
2: 90 percent / 4 M NaOH / ethanol / 2 h / Heating
3: 1) HBF4, NaNO2, 2) Cu, NaNO2 / 1) H2O, 30 min, 2) H2O, 1 h
4: 75 percent / conc. HCl / methanol / 0.5 h / 120 °C
5: 31 percent / KI / toluene / 100 - 110 °C
6: 60 percent / HF, potassium carbonate, potassium oxalate, kryptofix 222 / dimethylsulfoxide / 0.33 h / 160 °C
View Scheme
cyclopropyl(4-nitrophenyl)methanone
93639-12-4

cyclopropyl(4-nitrophenyl)methanone

haloperidol
52-86-8

haloperidol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 75 percent / conc. HCl / methanol / 0.5 h / 120 °C
2: 31 percent / KI / toluene / 100 - 110 °C
3: 60 percent / HF, potassium carbonate, potassium oxalate, kryptofix 222 / dimethylsulfoxide / 0.33 h / 160 °C
View Scheme
4-chloro-4'-nitrobutyrophenone
93639-13-5

4-chloro-4'-nitrobutyrophenone

haloperidol
52-86-8

haloperidol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 31 percent / KI / toluene / 100 - 110 °C
2: 60 percent / HF, potassium carbonate, potassium oxalate, kryptofix 222 / dimethylsulfoxide / 0.33 h / 160 °C
View Scheme
4-(4-fluorophenyl)-4-oxo-n-butyl chloride
3874-54-2

4-(4-fluorophenyl)-4-oxo-n-butyl chloride

haloperidol
52-86-8

haloperidol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: p-toluenesulfonic acid / benzene / 12 h / Heating
2: K2CO3, KI / dimethylformamide / 17.5 h / 100 °C
3: 65 percent / conc. HCl / methanol / 6 h / Heating
View Scheme
4-chloro-1-(4-fluorophenyl)-1,1-(ethylenedioxy)butane
3308-94-9

4-chloro-1-(4-fluorophenyl)-1,1-(ethylenedioxy)butane

haloperidol
52-86-8

haloperidol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: K2CO3, KI / dimethylformamide / 17.5 h / 100 °C
2: 65 percent / conc. HCl / methanol / 6 h / Heating
View Scheme
fluorobenzene
462-06-6

fluorobenzene

haloperidol
52-86-8

haloperidol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: AlCl3
2: toluene
View Scheme
4-Brom-4-(4-chlor-phenyl)-piperidin
91335-13-6

4-Brom-4-(4-chlor-phenyl)-piperidin

haloperidol
52-86-8

haloperidol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: NaOH-solution; water
2: toluene
View Scheme
reduced haloperidol
34104-67-1

reduced haloperidol

haloperidol
52-86-8

haloperidol

Conditions
ConditionsYield
With manganese dioxide In chloroform
1-(4-chlorobut-1-yn-1-yl)-4-fluorobenzene
1183278-95-6

1-(4-chlorobut-1-yn-1-yl)-4-fluorobenzene

haloperidol
52-86-8

haloperidol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: iron(III) chloride; water; silver(I) triflimide / 1,4-dioxane / 18 h
2: potassium iodide / toluene / 25 h / 125 °C
View Scheme
Multi-step reaction with 2 steps
1: bis(trifluoromethanesulfonyl)amide; water / 1,4-dioxane / 100 °C
2: potassium iodide; sodium hydrogencarbonate / toluene / 100 °C
View Scheme
bromochlorobenzene
106-39-8

bromochlorobenzene

haloperidol
52-86-8

haloperidol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: iodine; magnesium / tetrahydrofuran / 4 h / 60 - 70 °C / Inert atmosphere
1.2: 6 h / 30 °C / Inert atmosphere
1.3: 3 h / 60 °C / Inert atmosphere
2.1: hydrogen; palladium on activated charcoal / water / 24 h / 25 °C / 750.08 Torr
3.1: potassium carbonate; potassium iodide / acetonitrile / 24 h / 75 °C
View Scheme
N-benzyl-2-piperidinone
4783-65-7

N-benzyl-2-piperidinone

haloperidol
52-86-8

haloperidol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: iodine; magnesium / tetrahydrofuran / 4 h / 60 - 70 °C / Inert atmosphere
1.2: 6 h / 30 °C / Inert atmosphere
1.3: 3 h / 60 °C / Inert atmosphere
2.1: hydrogen; palladium on activated charcoal / water / 24 h / 25 °C / 750.08 Torr
3.1: potassium carbonate; potassium iodide / acetonitrile / 24 h / 75 °C
View Scheme
N-benzyl-4-(4-chlorophenyl)-4-hydroxypiperidin
56108-25-9

N-benzyl-4-(4-chlorophenyl)-4-hydroxypiperidin

haloperidol
52-86-8

haloperidol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: hydrogen; palladium on activated charcoal / water / 24 h / 25 °C / 750.08 Torr
2: potassium carbonate; potassium iodide / acetonitrile / 24 h / 75 °C
View Scheme
haloperidol
52-86-8

haloperidol

C21H21(2)H2ClFNO2

C21H21(2)H2ClFNO2

Conditions
ConditionsYield
With tris(pentafluorophenyl)borate; water-d2 In toluene at 100℃; for 12h; Inert atmosphere; regioselective reaction;97%
With [(N,N′-bis(2,6-diisopropylphenyl)-2,3-butanediimine)Ni(μ−H)]2; deuterium at -196 - 80℃; under 760.051 Torr; for 24h; Reagent/catalyst; Sealed tube;32 mg
haloperidol
52-86-8

haloperidol

benzoyl chloride
98-88-4

benzoyl chloride

benzoic acid haloperidol ester

benzoic acid haloperidol ester

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane for 24h; Inert atmosphere;96.7%
haloperidol
52-86-8

haloperidol

Haloperidol N-oxide

Haloperidol N-oxide

Conditions
ConditionsYield
With perfluoro-cis-2-n-butyl-3-n-propyloxaziridine; HCFC-225ca,cb In dichloromethane at -60℃; for 0.333333h;96%
In CaH2; dichloromethane71%
haloperidol
52-86-8

haloperidol

4-[4-(4-deuteriophenyl)-4-hydroxypiperidino]-4′-fluorobutyrophenone

4-[4-(4-deuteriophenyl)-4-hydroxypiperidino]-4′-fluorobutyrophenone

Conditions
ConditionsYield
With bis(η3-allyl-μ-chloropalladium(II)); 1-deuteriodiphenylmethanol; 3-(2,6-dibenzhydryl-4-methylphenyl)-4,5-dimethyl-1-(2,4,6-trimethylbenzyl)imidazolium chloride; caesium carbonate In toluene at 90℃; for 16h; Inert atmosphere;94%
haloperidol
52-86-8

haloperidol

7,7',8,8'-tetracyanoquinodimethane
1518-16-7

7,7',8,8'-tetracyanoquinodimethane

C21H23ClFNO2*C12H4N4
1421948-04-0

C21H23ClFNO2*C12H4N4

Conditions
ConditionsYield
In methanol; chloroform at 20℃; for 0.75h;93%
haloperidol
52-86-8

haloperidol

cyclohexylamine
108-91-8

cyclohexylamine

4-<4-(4-Chlorophenyl)-4-hydroxypiperidino>-4'-(cyclohexylamino)butyrophenone

4-<4-(4-Chlorophenyl)-4-hydroxypiperidino>-4'-(cyclohexylamino)butyrophenone

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide for 5h; Heating;92%
haloperidol
52-86-8

haloperidol

N,N-dimethylethylenediamine
108-00-9

N,N-dimethylethylenediamine

4-<4-(4-Chlorophenyl)-4-hydroxypiperidino>-4'-<<2-(dimethylamino)ethyl>amino>butyrophenone

4-<4-(4-Chlorophenyl)-4-hydroxypiperidino>-4'-<<2-(dimethylamino)ethyl>amino>butyrophenone

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide for 5h; Heating;92%
2-(2-methylphenyl)pyridine
10273-89-9

2-(2-methylphenyl)pyridine

haloperidol
52-86-8

haloperidol

C33H33FN2O2

C33H33FN2O2

Conditions
ConditionsYield
With C17H24N5Ru(1+)*F6P(1-); potassium acetate; potassium carbonate In 1-methyl-pyrrolidin-2-one at 35℃; for 48h; Inert atmosphere;92%
haloperidol
52-86-8

haloperidol

3-trifluoromethylaniline
98-16-8

3-trifluoromethylaniline

1-(4-fluorophenyl)-4-(4-hydroxy-4-(4-((3-(trifluoromethyl)phenyl)amino)phenyl)piperidin-1-yl)butan-1-one
1612891-27-6

1-(4-fluorophenyl)-4-(4-hydroxy-4-(4-((3-(trifluoromethyl)phenyl)amino)phenyl)piperidin-1-yl)butan-1-one

Conditions
ConditionsYield
With Pd-PEPPSI-(2,6-(3-pentyl)pentylphenyl-2H-imidazol-2-ylidene)Cl-o-picoline; caesium carbonate In 1,2-dimethoxyethane at 45℃; for 24h; Buchwald-Hartwig Coupling; Inert atmosphere; Glovebox;91%
haloperidol
52-86-8

haloperidol

reduced haloperidol
34104-67-1

reduced haloperidol

Conditions
ConditionsYield
With sodium tetrahydroborate In methanol at 20℃; for 1.33333h;90%
With sodium tetrahydroborate In ethanol at 0 - 20℃;90%
With human liver dihydrodiol dehydrogenase 1; NADPH In phosphate buffer at 25℃; pH=6.0; Enzyme kinetics; Further Variations:; Reagents;
1,2-propanediene
463-49-0

1,2-propanediene

haloperidol
52-86-8

haloperidol

C24H29ClFNO2

C24H29ClFNO2

Conditions
ConditionsYield
Stage #1: haloperidol With copper diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In tetrahydrofuran for 0.0833333h; Inert atmosphere;
Stage #2: 1,2-propanediene With (dimethoxy)methylsilane In tetrahydrofuran at 20℃; for 12h; Inert atmosphere;
90%
piperidine
110-89-4

piperidine

haloperidol
52-86-8

haloperidol

4-<4-(4-Chlorophenyl)-4-hydroxypiperidino>-4'-piperidinobutyrophenone

4-<4-(4-Chlorophenyl)-4-hydroxypiperidino>-4'-piperidinobutyrophenone

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide for 3h; Ambient temperature;89%
haloperidol
52-86-8

haloperidol

2,4,6-Trinitrophenol
88-89-1

2,4,6-Trinitrophenol

C21H23ClFNO2*C6H3N3O7
1216665-74-5

C21H23ClFNO2*C6H3N3O7

Conditions
ConditionsYield
In methanol; chloroform at 20℃; for 0.75h;89%
haloperidol
52-86-8

haloperidol

C21H19(2)H4ClFNO2

C21H19(2)H4ClFNO2

Conditions
ConditionsYield
With [(N,N’-bis(1R,2R,3R,5S)-(−)-isopinocampheyl-1,2-ethanediimine-radical)NiI(μ2-H)]2; deuterium at -196 - 80℃; under 760.051 Torr; for 24h; Reagent/catalyst; Sealed tube;89%
1.3-propanedithiol
109-80-8

1.3-propanedithiol

haloperidol
52-86-8

haloperidol

(1,3-propanethioacetal)-4-[4-(p-chlorophenyl)-4-hydroxypiperidinyl]-4'-fluorobutyrophenone

(1,3-propanethioacetal)-4-[4-(p-chlorophenyl)-4-hydroxypiperidinyl]-4'-fluorobutyrophenone

Conditions
ConditionsYield
With trifluoroborane diethyl ether In methanol; hexane; dichloromethane; ethyl acetate88%
haloperidol
52-86-8

haloperidol

1-ethylpropylzinc bromide

1-ethylpropylzinc bromide

1-(4-fluorophenyl)-4-(4-hydroxy-4-(4-(pentan-3-yl)phenyl)piperidin-1-yl)butan-1-one

1-(4-fluorophenyl)-4-(4-hydroxy-4-(4-(pentan-3-yl)phenyl)piperidin-1-yl)butan-1-one

Conditions
ConditionsYield
Stage #1: haloperidol With C40H55Cl5N3Pd In toluene at 0℃; for 0.0833333h; Negishi Coupling; Inert atmosphere; Cooling with ice;
Stage #2: 1-ethylpropylzinc bromide In tetrahydrofuran; toluene at 23℃; for 16h; Inert atmosphere;
88%
haloperidol
52-86-8

haloperidol

propargyl bromide
106-96-7

propargyl bromide

C24H26ClFNO2(1+)*Br(1-)

C24H26ClFNO2(1+)*Br(1-)

Conditions
ConditionsYield
In tetrahydrofuran for 2h; Solvent; Temperature; Inert atmosphere; Reflux;88%
haloperidol
52-86-8

haloperidol

(+)-Dihydrohaloperidol

(+)-Dihydrohaloperidol

Conditions
ConditionsYield
With C37H40MnN2O2P2(1+)*Br(1-); sodium t-butanolate In isopropyl alcohol; toluene at 50℃; for 6h; Inert atmosphere; Schlenk technique; enantioselective reaction;85%
haloperidol
52-86-8

haloperidol

A

C42H47F2N3O4

C42H47F2N3O4

B

4-<4-hydroxy-4-(4-aminophenyl)piperidinyl>-1-(4-fluorophenyl)butanone
114361-10-3

4-<4-hydroxy-4-(4-aminophenyl)piperidinyl>-1-(4-fluorophenyl)butanone

Conditions
ConditionsYield
With C46H71Cl3N2Pd; ammonia; sodium t-butanolate In 1,4-dioxane at 80℃; for 2h; Inert atmosphere; Schlenk technique;A n/a
B 84%
haloperidol
52-86-8

haloperidol

4-(4-chlorophenyl)-1-<4-(4-fluorophenyl)-4-oxobutyl>-1,2,3,6-tetrahydopyridine
52669-92-8

4-(4-chlorophenyl)-1-<4-(4-fluorophenyl)-4-oxobutyl>-1,2,3,6-tetrahydopyridine

Conditions
ConditionsYield
With hydrogenchloride; acetic acid for 24h; Reflux; Inert atmosphere;84%
N-tert-butyldimethylsilyl-S-fluoromethyl-S-(2-pyridyl)sulfoximine

N-tert-butyldimethylsilyl-S-fluoromethyl-S-(2-pyridyl)sulfoximine

haloperidol
52-86-8

haloperidol

(E)-4-(4-chlorophenyl)-1-(5-fluoro-4-(4-fluorophenyl)pent-4-enyl)piperidin-4-ol

(E)-4-(4-chlorophenyl)-1-(5-fluoro-4-(4-fluorophenyl)pent-4-enyl)piperidin-4-ol

Conditions
ConditionsYield
Stage #1: N-tert-butyldimethylsilyl-S-fluoromethyl-S-(2-pyridyl)sulfoximine With potassium hexamethylsilazane In tetrahydrofuran at -78℃; for 0.5h; Inert atmosphere;
Stage #2: haloperidol In tetrahydrofuran at -78℃; for 3h; Inert atmosphere; stereoselective reaction;
82%
haloperidol
52-86-8

haloperidol

1-amino-3-(dimethylamino)propane
109-55-7

1-amino-3-(dimethylamino)propane

4-<4-(4-Chlorophenyl)-4-hydroxypiperidino>-4'-<<3-(dimethylamino)propyl>amino>butyrophenone

4-<4-(4-Chlorophenyl)-4-hydroxypiperidino>-4'-<<3-(dimethylamino)propyl>amino>butyrophenone

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide for 3h; Heating;80%
haloperidol
52-86-8

haloperidol

2-(aminooxy)-N,N-diethylethanamine dihydrochloride
21894-85-9, 87272-47-7, 113437-87-9

2-(aminooxy)-N,N-diethylethanamine dihydrochloride

4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one O-(2-diethylamino-ethyl)-oxime

4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one O-(2-diethylamino-ethyl)-oxime

Conditions
ConditionsYield
With pyridine In ethanol for 32h; Heating;76.9%
haloperidol
52-86-8

haloperidol

butan-1-ol
71-36-3

butan-1-ol

1-(n-Butoxyphenyl)-4-<4-(4-chlorophenyl)-4-hydroxypiperidino>-n-butyl alcohol

1-(n-Butoxyphenyl)-4-<4-(4-chlorophenyl)-4-hydroxypiperidino>-n-butyl alcohol

Conditions
ConditionsYield
With sodium amide for 1h; Heating;75%
haloperidol
52-86-8

haloperidol

4-(4'-chlorophenyl)-1-(4'-(4-fluorophenyl)butyl)piperidin-4-ol
164668-08-0

4-(4'-chlorophenyl)-1-(4'-(4-fluorophenyl)butyl)piperidin-4-ol

Conditions
ConditionsYield
With [(C6H6)(PCy3)(CO)RuH]+*BF4−; hydrogen; phenol In 1,4-dioxane; isopropyl alcohol under 1520.1 Torr; for 12h; Inert atmosphere; Glovebox; Schlenk technique; chemoselective reaction;68%
haloperidol
52-86-8

haloperidol

O-(2-Pyrrolidin-1-yl-ethyl)-hydroxylamine; hydrochloride

O-(2-Pyrrolidin-1-yl-ethyl)-hydroxylamine; hydrochloride

4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one O-(2-pyrrolidin-1-yl-ethyl)-oxime

4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one O-(2-pyrrolidin-1-yl-ethyl)-oxime

Conditions
ConditionsYield
With pyridine In ethanol for 32h; Heating;67.7%
3-(tert-butyloxycarbonylamino)propionic acid
3303-84-2

3-(tert-butyloxycarbonylamino)propionic acid

haloperidol
52-86-8

haloperidol

C29H36ClFN2O5
853994-07-7

C29H36ClFN2O5

Conditions
ConditionsYield
Stage #1: 3-(tert-butyloxycarbonylamino)propionic acid; haloperidol With dmap In dichloromethane for 0.5h; Cooling with ice;
Stage #2: With dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 25h; Cooling with ice;
64.6%

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