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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

6-Bromoindole

Cas:52415-29-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

CHemwill -- 6-Bromoindole

Cas:52415-29-9

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Manufacturers

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

6-Bromo-1H-indole/ LIDE PHARMA- Factory supply / Best price

Cas:52415-29-9

Min.Order:1 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

TIANFUCHEM- 6-Bromo-1H-indole

Cas:52415-29-9

Min.Order:1 Kilogram

FOB Price: $2000.0

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be sent

6-Bromo-1H-indole

Cas:52415-29-9

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 52415-29-9 with fast shipping

Cas:52415-29-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages High purity, all above 98.5%, no impurities after dissolution We will test each batch to ensure quality OEM and private brand services designed for free Various cap colors available We can also provide MT1 peptide powd

6-Bromo-1H-indole

Cas:52415-29-9

Min.Order:1 Kilogram

FOB Price: $50.0 / 100.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Product Name: 6-Bromo-1H-indole Synonyms: EOS-60560;6-Bromoindole in stock Factory;bromoindole;BROMOINDOLE-6;6-BROMO-1H-INDOLE;6-BROMOINDOLE;6-Bromoindole,98%;bromoindole 6-Bromoindole CAS:

6-Bromo-1H-indole CAS: 52415-29-9

Cas:52415-29-9

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

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Henan Wentao Chemical Product Co., Ltd.

We are leading fine chemicals supplier in China with ISO certificate, Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...) 2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...) 3.OLED

6-BromoindoleCAS NO.: 52415-29-9

Cas:52415-29-9

Min.Order:1 Gram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:Powder Storage:Store in sealed containers at cool & dry pla

High purity cas 52415-29-9 6-Bromoindole / Bromoindole

Cas:52415-29-9

Min.Order:100 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

6-Bromoindole 52415-29-9

Cas:52415-29-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

6-Bromo-1H-indole CAS: 52415-29-9 Important Material Chemical Intermediate

Cas:52415-29-9

Min.Order:1 Kilogram

FOB Price: $56.0 / 58.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

6-Bromo-1H-indole CAS:52415-29-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic interme

6-Bromo-1H-indole CAS:52415-29-9

Cas:52415-29-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

6-Bromoindole

Cas:52415-29-9

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

6-Bromoindole

Cas:52415-29-9

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

6-bromoindole

Cas:52415-29-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

6-Bromo-1H-indole

Cas:52415-29-9

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Bromoindole

Cas:52415-29-9

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Shanghai Send Pharmaceutical Technology Co., Ltd.

low price high quality high purity good sevice stock Appearance:white Storage:Preserve In Well-Closed, Light-Resistant and Tight Containers. Store In Cool & Dry Place Package:1g,5g,10g...1kg,5kg...more Application:Pharmaceutical interme

6-Bromo-1H-indole

Cas:52415-29-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

6-Bromo-1H-indole

Cas:52415-29-9

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

6-Bromoindole

Cas:52415-29-9

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

6-Bromoindole

Cas:52415-29-9

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

moderate price & quick delivery. Appearance:white to brown powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:100g/bottle,1kg/bottle,25kg/drum or as per your request Application:6-Bromoindole is a starting

6-Bromo-1H-indole

Cas:52415-29-9

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction to our products and services. If you are interested in our products, please contact us via email product quality √ 1.

6-Bromo-1H-indole

Cas:52415-29-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

6-Bromo-1H-indole

Cas:52415-29-9

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

6-Bromo-1H-indole Basic information Product Name: 6-Bromo-1H-indole Synonyms: EOS-60560;6-Bromoindole in stock Factory;bromoindole;BROMOINDOLE-6;6-BROMO-1H-INDOLE;6-BROMOINDOLE;6-Bromoindole,98%;bromoindole 6-Bromoindole CAS: 52415-29-9 MF:

6-Bromo-1H-indole

Cas:52415-29-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

6-Bromoindole

Cas:52415-29-9

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

6-Bromo-1H-indole

Cas:52415-29-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

6-Bromoindole

Cas:52415-29-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

6-Bromoindole

Cas:52415-29-9

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Synthetic route

6-bromo-indole-2-carboxylic acid(Ref.7.)
16732-65-3

6-bromo-indole-2-carboxylic acid(Ref.7.)

6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

Conditions
ConditionsYield
With quinoline; copper Heating;98%
With copper In quinoline Heating;95%
With quinoline; copper(I) bromide
(E)-2-(4-bromo-2-nitrophenyl)-N,N-dimethylethyleneamine
99474-21-2

(E)-2-(4-bromo-2-nitrophenyl)-N,N-dimethylethyleneamine

6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

Conditions
ConditionsYield
With iron(III) chloride hexahydrate; pyrographite; hydrazine hydrate In ethanol at 75℃; for 7h;93%
With zinc In acetic acid at 85℃; for 2h;62%
With acetic acid; zinc In methanol; dichloromethane Heating;52%
With acetic acid; zinc at 75 - 85℃; for 3.5h;2.675 g
4-bromo-2-nitrotoluene
60956-26-5

4-bromo-2-nitrotoluene

N,N-dimethyl-formamide dimethyl acetal
4637-24-5

N,N-dimethyl-formamide dimethyl acetal

6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

Conditions
ConditionsYield
Stage #1: 4-bromo-2-nitrotoluene; N,N-dimethyl-formamide dimethyl acetal With pyrrolidine In N,N-dimethyl-formamide at 110℃; for 2h;
Stage #2: With hydrogenchloride; titanium(III) chloride; ammonium acetate In N,N-dimethyl-formamide at 0℃; for 0.25h;
90%
Stage #1: 4-bromo-2-nitrotoluene; N,N-dimethyl-formamide dimethyl acetal With pyrrolidine In 1,4-dioxane at 102℃; for 3.5h; Leimgruber-Batcho Indole Synthesis; Reflux; Inert atmosphere;
Stage #2: With hydrazine hydrate In 1,4-dioxane at 45℃; for 1h; Leimgruber-Batcho Indole Synthesis;
82%
Stage #1: 4-bromo-2-nitrotoluene; N,N-dimethyl-formamide dimethyl acetal With pyrrolidine In N,N-dimethyl-formamide at 105 - 110℃; for 21h; Leimgruber-Batcho Indole Synthesis;
Stage #2: With acetic acid; zinc at 70 - 90℃; for 3h; Temperature; Reagent/catalyst; Leimgruber-Batcho Indole Synthesis;
56%
6-bromo-2,3-dihydro-1H-indole-2-one
99365-40-9

6-bromo-2,3-dihydro-1H-indole-2-one

6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

Conditions
ConditionsYield
With bis(trimethylsilyl)amide yttrium(III); 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane In toluene at 120℃; for 36h; Inert atmosphere;90%
6-bromo-1-(4-methylphenylsulfonyl)-1H-indole
189265-99-4

6-bromo-1-(4-methylphenylsulfonyl)-1H-indole

6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl acetamide at 60℃; for 5h; Inert atmosphere;85%
1-indoline
496-15-1

1-indoline

6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

Conditions
ConditionsYield
Stage #1: 1-indoline With silver(II) sulfate; sulfuric acid for 0.5h;
Stage #2: With bromine for 0.5h;
Stage #3: With chloranil In 5,5-dimethyl-1,3-cyclohexadiene for 5h; Reflux;
73%
(2S)-2-amino-3-(6-bromo-1H-indol-3-yl)propanoic acid
52448-17-6

(2S)-2-amino-3-(6-bromo-1H-indol-3-yl)propanoic acid

6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

Conditions
ConditionsYield
With dipotassium hydrogenphosphate; tryptophanase TnaA at 25℃; pH=7.4; Enzymatic reaction;70.4%
1-[(E)-2-(4-bromo-2-nitrophenyl)vinyl]pyrrolidine

1-[(E)-2-(4-bromo-2-nitrophenyl)vinyl]pyrrolidine

6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

Conditions
ConditionsYield
With ammonium hydroxide; iron(II) sulfate Heating;31%
β-dimethylamino-2-nitrostyrene
78508-22-2

β-dimethylamino-2-nitrostyrene

6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

Conditions
ConditionsYield
With acetic acid; zinc In water at 75℃; for 1h; Stirred;27%
With hydrogen; W-2 Raney nickel In ethanol340 mg
With acetic acid; zinc
With hydrogen In benzene under 2585.81 Torr; for 26h;0.29 g
pyrrolidine
123-75-1

pyrrolidine

4-bromo-2-nitrotoluene
60956-26-5

4-bromo-2-nitrotoluene

N,N-dimethyl-formamide dimethyl acetal
4637-24-5

N,N-dimethyl-formamide dimethyl acetal

6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

Conditions
ConditionsYield
With ammonium acetate; titanium(III) chloride 1) DMF, 100-110 deg C, 2 h, 2) water, DMF; Yield given. Multistep reaction;
With zinc In hexane; acetic acid; N,N-dimethyl-formamide
With zinc In hexane; acetic acid; N,N-dimethyl-formamide
With zinc In hexane; acetic acid; N,N-dimethyl-formamide
6-bromo-indoline
63839-24-7

6-bromo-indoline

6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

Conditions
ConditionsYield
With dimethylsulfide; tert-butylhypochlorite; sodium ethanolate; triethylamine 1.) -65 deg C, CH2Cl2, 1 h, 2.) -65 deg C --> RT, 2 h; Yield given. Multistep reaction;
(5-Bromo-2-trimethylsilanylethynyl-phenyl)-carbamic acid ethyl ester
112671-54-2

(5-Bromo-2-trimethylsilanylethynyl-phenyl)-carbamic acid ethyl ester

6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

Conditions
ConditionsYield
With sodium ethanolate In ethanol Heating; Yield given;
(E)-4-bromo-2-nitro-β-piperidinostyrene
108061-73-0

(E)-4-bromo-2-nitro-β-piperidinostyrene

6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

Conditions
ConditionsYield
With titanium(III) chloride; ammonium acetate buffer In water; acetone for 0.166667h; Yield given;
6-amino-1H-indole
5318-27-4

6-amino-1H-indole

6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

Conditions
ConditionsYield
With hydrogenchloride; copper(I) bromide; sodium nitrite 1.) 0 deg C, 5 min, 2.) H2O, -10 deg C, 3 h; Yield given. Multistep reaction;
4-bromo-2-nitrotoluene
60956-26-5

4-bromo-2-nitrotoluene

6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: CuI; DMF / 0.33 h / 180 °C / 6000.6 - 7500.75 Torr / microwave irradiation
2: 52 percent / Zn; AcOH / methanol; CH2Cl2 / Heating
View Scheme
Multi-step reaction with 2 steps
1: pyrrolidine / dimethylformamide / 1 h / 110 °C
2: 2.675 g / Zn; aq. HOAc / 3.5 h / 75 - 85 °C
View Scheme
Multi-step reaction with 2 steps
1: 4 h / 110 °C
2: 20percent TiCl3, 4M ammonium acetate buffer / H2O; acetone / 0.17 h
View Scheme
2,4-dinitrotoluene
121-14-2

2,4-dinitrotoluene

alkali

alkali

6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 99 percent / 2 h / Heating
2: 64 percent / aluminum amalgam / H2O / 5 h / Irradiation
3: 1.) 1M aq. HCl, sodium nitrite, 2.) CuBr / 1.) 0 deg C, 5 min, 2.) H2O, -10 deg C, 3 h
View Scheme
(E)-2-(2,4-dinitrophenyl)-N,N-dimethyl-1-ethenamine
61293-29-6

(E)-2-(2,4-dinitrophenyl)-N,N-dimethyl-1-ethenamine

6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 64 percent / aluminum amalgam / H2O / 5 h / Irradiation
2: 1.) 1M aq. HCl, sodium nitrite, 2.) CuBr / 1.) 0 deg C, 5 min, 2.) H2O, -10 deg C, 3 h
View Scheme
4-Methyl-3-nitroanilin
119-32-4

4-Methyl-3-nitroanilin

6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 1.) sodium nitrite, 16percent HBr, 2.) copper(I) bromide / 1.) water, -1 deg C, 2.) water, 70 deg C, 1 h
2: 4 h / 110 °C
3: 20percent TiCl3, 4M ammonium acetate buffer / H2O; acetone / 0.17 h
View Scheme
Multi-step reaction with 2 steps
1.1: hydrogen bromide / water / 0.33 h / Reflux
1.2: 0.25 h / 0 °C
1.3: 0 °C / Heating
2.1: pyrrolidine / N,N-dimethyl-formamide / 21 h / 105 - 110 °C
2.2: 3 h / 70 - 90 °C
View Scheme
Multi-step reaction with 3 steps
1.1: hydrogen bromide / water / 0.33 h / Reflux
1.2: 0.25 h / 0 °C
1.3: 0 °C / Heating
2.1: 5.5 h / 110 °C
3.1: hydrogen / benzene / 26 h / 2585.81 Torr
View Scheme
Multi-step reaction with 3 steps
1.1: hydrogen bromide / water / 0.33 h / Reflux
1.2: 0.25 h / 0 °C
1.3: 0 °C / Heating
2.1: N,N-dimethyl-formamide / 21 h / 105 - 110 °C
3.1: acetic acid; zinc / 3 h / 70 - 90 °C
View Scheme
N-(4-bromo-2-nitrophenyl)acetamide
881-50-5

N-(4-bromo-2-nitrophenyl)acetamide

6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 3N KOH / 24 h / Heating
2: 1.) sodium nitrite, 5N HCl; 2.) aq. KI / 1.) 0-10 deg C; 2.) RT, 30 min
3: 69 percent / SnCl2, conc. HCl / ethanol / 0.25 h / 50 - 60 °C
4: 72 percent / pyridine / 3 h / 0-10 deg C
5: CuI, Et3N / Pd(PPh3)2Cl2 / 60 °C
6: NaOEt / ethanol / Heating
View Scheme
4-bromoacetanilide
103-88-8

4-bromoacetanilide

6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: HNO3 / 8 min below 0 deg C, 8 min, RT.
2: 3N KOH / 24 h / Heating
3: 1.) sodium nitrite, 5N HCl; 2.) aq. KI / 1.) 0-10 deg C; 2.) RT, 30 min
4: 69 percent / SnCl2, conc. HCl / ethanol / 0.25 h / 50 - 60 °C
5: 72 percent / pyridine / 3 h / 0-10 deg C
6: CuI, Et3N / Pd(PPh3)2Cl2 / 60 °C
7: NaOEt / ethanol / Heating
View Scheme
4-Bromo-2-nitroaniline
875-51-4

4-Bromo-2-nitroaniline

6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 1.) sodium nitrite, 5N HCl; 2.) aq. KI / 1.) 0-10 deg C; 2.) RT, 30 min
2: 69 percent / SnCl2, conc. HCl / ethanol / 0.25 h / 50 - 60 °C
3: 72 percent / pyridine / 3 h / 0-10 deg C
4: CuI, Et3N / Pd(PPh3)2Cl2 / 60 °C
5: NaOEt / ethanol / Heating
View Scheme
1-iodo-4-bromo-2-nitrobenzene
112671-42-8

1-iodo-4-bromo-2-nitrobenzene

6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 69 percent / SnCl2, conc. HCl / ethanol / 0.25 h / 50 - 60 °C
2: 72 percent / pyridine / 3 h / 0-10 deg C
3: CuI, Et3N / Pd(PPh3)2Cl2 / 60 °C
4: NaOEt / ethanol / Heating
View Scheme
5-bromo-2-iodo-aniline
64085-52-5

5-bromo-2-iodo-aniline

6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 72 percent / pyridine / 3 h / 0-10 deg C
2: CuI, Et3N / Pd(PPh3)2Cl2 / 60 °C
3: NaOEt / ethanol / Heating
View Scheme
ethyl (5-bromo-2-iodophenyl)carbamate
112671-48-4

ethyl (5-bromo-2-iodophenyl)carbamate

6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: CuI, Et3N / Pd(PPh3)2Cl2 / 60 °C
2: NaOEt / ethanol / Heating
View Scheme
3-(4-bromo-2-nitrophenyl)-2-oxopropanoic acid
99365-39-6

3-(4-bromo-2-nitrophenyl)-2-oxopropanoic acid

6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Fe(OH)2; H2O
2: quinoline; copper (I)-bromide
View Scheme
1-[2-(4-bromo-2-nitrophenyl)ethenyl]pyrrolidine

1-[2-(4-bromo-2-nitrophenyl)ethenyl]pyrrolidine

6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

Conditions
ConditionsYield
With acetic acid; zinc at 75 - 85℃; for 3h;1.7 g
With acetic acid; zinc at 70 - 90℃; for 3h; Reagent/catalyst;7.19 g
Ν,Ν-dimethylacetamide dimethyl acetal
25408-61-1

Ν,Ν-dimethylacetamide dimethyl acetal

4-bromo-2-nitrotoluene
60956-26-5

4-bromo-2-nitrotoluene

6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

Conditions
ConditionsYield
Stage #1: Ν,Ν-dimethylacetamide dimethyl acetal; 4-bromo-2-nitrotoluene With pyrrolidine In N,N-dimethyl-formamide at 110℃; for 3h;
Stage #2: With acetic acid; zinc In water at 75 - 85℃; for 2h;
L-Tryptophan
73-22-3

L-Tryptophan

6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium bromide; disodium hydrogenphosphate; tryptophan halogenase / 72 h / 25 °C / pH 7.4 / Enzymatic reaction
2: tryptophanase TnaA; dipotassium hydrogenphosphate / 25 °C / pH 7.4 / Enzymatic reaction
View Scheme
indole
120-72-9

indole

6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: acetic acid; sodium cyanoborohydride / 2 h / 15 °C
2.1: sulfuric acid; silver(II) sulfate / 0.5 h
2.2: 0.5 h
2.3: 5 h / Reflux
View Scheme
6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

6-bromo-1H-indole-3-carbaldehyde
17826-04-9

6-bromo-1H-indole-3-carbaldehyde

Conditions
ConditionsYield
With trichlorophosphate at 0 - 40℃; for 2.5h; Inert atmosphere;100%
With trichlorophosphate at 0 - 20℃; Vilsmeier-Haack Formylation; Inert atmosphere;99%
With sodium hydroxide; trichlorophosphate Vilsmeier-Haack reaction;98%
6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

6-bromo-1-(tert-butyldimethylsilyl)-1H-indole
184637-11-4

6-bromo-1-(tert-butyldimethylsilyl)-1H-indole

Conditions
ConditionsYield
Stage #1: 6-bromo-1H-indole With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 0.5h;
Stage #2: tert-butyldimethylsilyl chloride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 1h;
100%
Stage #1: 6-bromo-1H-indole With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; for 0.75h; Inert atmosphere;
Stage #2: tert-butyldimethylsilyl chloride In tetrahydrofuran; mineral oil at 0 - 20℃; for 12h; Inert atmosphere;
90%
Stage #1: 6-bromo-1H-indole With sodium hydride In N,N-dimethyl-formamide at 0 - 10℃; for 0.5h; Inert atmosphere;
Stage #2: tert-butyldimethylsilyl chloride In N,N-dimethyl-formamide at 20℃; Inert atmosphere;
73%
With n-butyllithium 1.) THF, hexane, -78 deg C, 15 min, 2.) THF, hexane, RT, 4 h; Yield given. Multistep reaction;
6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

3-iodo-6-bromoindole
372077-73-1

3-iodo-6-bromoindole

Conditions
ConditionsYield
With potassium hydroxide; iodine In N,N-dimethyl-formamide at 20℃;100%
With potassium hydroxide; iodine In N,N-dimethyl-formamide Ambient temperature;
Stage #1: 6-bromo-1H-indole With sodium hydroxide In methanol at 20℃; for 0.166667h;
Stage #2: With iodine; potassium iodide In methanol at 20℃; for 3h;
134 mg
6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

methyl iodide
74-88-4

methyl iodide

6-bromo-1-methyl-1H-indole
125872-95-9

6-bromo-1-methyl-1H-indole

Conditions
ConditionsYield
With potassium hydroxide In acetone at 0 - 25℃;100%
Stage #1: 6-bromo-1H-indole With sodium hydride In 1,2-dimethoxyethane; dimethyl sulfoxide at 20℃; for 0.5h;
Stage #2: methyl iodide In 1,2-dimethoxyethane; dimethyl sulfoxide at 20℃;
95%
Stage #1: 6-bromo-1H-indole With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.5h; Inert atmosphere;
Stage #2: methyl iodide In N,N-dimethyl-formamide at 20℃; for 2h; Inert atmosphere;
93.1%
6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

(E)-N,N-dimethyl-2-nitroethenamine
73430-27-0

(E)-N,N-dimethyl-2-nitroethenamine

3-<(E)-2-nitroethenyl>-6-bromoindole
222173-67-3

3-<(E)-2-nitroethenyl>-6-bromoindole

Conditions
ConditionsYield
Stage #1: (E)-N,N-dimethyl-2-nitroethenamine In trifluoroacetic acid at 20℃; for 0.0833333h; Michael Addition; Inert atmosphere;
Stage #2: 6-bromo-1H-indole In dichloromethane at 20℃; for 0.75h; Inert atmosphere;
100%
With trifluoroacetic acid at 20℃; for 0.5h;96%
6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-1(2H)-pyridinecarboxylate
375853-82-0, 286961-14-6

tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-1(2H)-pyridinecarboxylate

tert-butyl 4-(1h-indol-6-yl)-5,6-dihydropyridine-1(2H)-carboxylate

tert-butyl 4-(1h-indol-6-yl)-5,6-dihydropyridine-1(2H)-carboxylate

Conditions
ConditionsYield
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate In 1,4-dioxane; water for 2h; Inert atmosphere;100%
6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

p-toluenesulfonyl chloride
98-59-9

p-toluenesulfonyl chloride

6-bromo-1-(4-methylphenylsulfonyl)-1H-indole
189265-99-4

6-bromo-1-(4-methylphenylsulfonyl)-1H-indole

Conditions
ConditionsYield
Stage #1: 6-bromo-1H-indole With sodium hydride In acetonitrile at 0℃; for 0.166667h;
Stage #2: p-toluenesulfonyl chloride In acetonitrile at 0 - 20℃; for 4h;
99%
With sodium hydride In acetonitrile at 0 - 20℃; for 4h;99%
With potassium hydroxide; tetra(n-butyl)ammonium hydrogensulfate In toluene for 4h;98%
6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

triisopropylsilyl chloride
13154-24-0

triisopropylsilyl chloride

6-bromo-1-(triisopropylsilyl)-1H-indole
299432-99-8

6-bromo-1-(triisopropylsilyl)-1H-indole

Conditions
ConditionsYield
Stage #1: 6-bromo-1H-indole With sodium hydride In tetrahydrofuran at 20℃; for 0.166667h;
Stage #2: triisopropylsilyl chloride In tetrahydrofuran at 20℃; for 0.5h;
99%
Stage #1: 6-bromo-1H-indole With sodium hydride In tetrahydrofuran at 20℃; for 0.166667h;
Stage #2: triisopropylsilyl chloride In tetrahydrofuran at 20℃; for 0.5h;
99%
Stage #1: 6-bromo-1H-indole With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; for 0.5h;
Stage #2: triisopropylsilyl chloride In tetrahydrofuran; mineral oil at 0 - 20℃;
96%
6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

6-bromoindole-1-carboxylic acid tert-butyl ester
147621-26-9

6-bromoindole-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With dmap In tetrahydrofuran at 20℃; for 4h;99%
With dmap In tetrahydrofuran at 20℃; Inert atmosphere;99%
With dmap In dichloromethane98%
6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

phenylboronic acid
98-80-6

phenylboronic acid

6-phenyl-1H-indole
106851-31-4

6-phenyl-1H-indole

Conditions
ConditionsYield
With Ti0.97Pd0.03O1.97; potassium carbonate In water at 100℃; for 6h; Suzuki-Miyaura Coupling;99%
With C20H20N2O2Pd; sodium hydrogencarbonate In water at 80℃; for 6h; Suzuki-Miyaura Coupling;94%
With potassium carbonate In water for 0.5h; Suzuki-Miyaura Coupling; Heating;90%
6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

2-Bromoethyl methyl ether
6482-24-2

2-Bromoethyl methyl ether

6-bromo-1-(2-methoxyethyl)-1H-indole

6-bromo-1-(2-methoxyethyl)-1H-indole

Conditions
ConditionsYield
Stage #1: 6-bromo-1H-indole With sodium hydride In 1,2-dimethoxyethane; dimethyl sulfoxide at 20℃; for 0.5h;
Stage #2: 2-Bromoethyl methyl ether In 1,2-dimethoxyethane; dimethyl sulfoxide at 20℃;
99%
6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

allyl bromide
106-95-6

allyl bromide

6-bromo-1-(prop-2-en-1-yl)-1H-indole
945399-52-0

6-bromo-1-(prop-2-en-1-yl)-1H-indole

Conditions
ConditionsYield
Stage #1: 6-bromo-1H-indole With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.5h;
Stage #2: allyl bromide In N,N-dimethyl-formamide at 20℃; for 0.5h;
99%
Stage #1: 6-bromo-1H-indole With sodium hydride In N,N-dimethyl-formamide at 20℃;
Stage #2: allyl bromide In N,N-dimethyl-formamide for 2h;
98%
Stage #1: 6-bromo-1H-indole With sodium hydride In N,N-dimethyl-formamide; mineral oil at 20℃; for 1h;
Stage #2: allyl bromide In N,N-dimethyl-formamide; mineral oil at 20℃; for 0.75h;
3.2 g
6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

thiophenol
108-98-5

thiophenol

6-bromo-3-(phenylthio)-1H-indole
945000-95-3

6-bromo-3-(phenylthio)-1H-indole

Conditions
ConditionsYield
With iodine; potassium iodide In ethanol; water at 20 - 60℃;99%
With iodine; potassium iodide In ethanol; water at 60℃; for 72h; Schlenk technique; Inert atmosphere;77%
6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

6-bromo-indoline
63839-24-7

6-bromo-indoline

Conditions
ConditionsYield
With sodium cyanoborohydride; acetic acid at 20℃;99%
With sodium cyanoborohydride; acetic acid for 1h;79%
With sodium cyanoborohydride; acetic acid at 10℃; for 1h;70%
6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

6-iodo-1 H-indole
115666-47-2

6-iodo-1 H-indole

Conditions
ConditionsYield
With copper(l) iodide; sodium iodide; N,N`-dimethylethylenediamine In 1,4-dioxane at 110℃; for 22h; Inert atmosphere; Sealed tube;99%
With copper(l) iodide; sodium iodide; N,N`-dimethylethylenediamine In 1,4-dioxane at 110℃; for 22h; Inert atmosphere;99%
With copper(l) iodide; sodium iodide; N,N`-dimethylethylenediamine In 1,4-dioxane at 110℃; for 22h; Microwave irradiation; Sealed tube; Inert atmosphere;97%
6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

ethyl 5-methyl-2-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-3-carboxylate
1533443-74-1

ethyl 5-methyl-2-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-3-carboxylate

ethyl (R)-5-methyl-3-(5-methyl-1H-indol-3-yl)-2-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-3-carboxylate
1533444-23-3

ethyl (R)-5-methyl-3-(5-methyl-1H-indol-3-yl)-2-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-3-carboxylate

Conditions
ConditionsYield
With C38H33O4P In toluene at -40℃; for 4h; enantioselective reaction;99%
6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

C14H13NO4

C14H13NO4

ethyl (S)-3-[3-(6-bromo-1H-indol-3-yl)-1-methyl-2-oxoindolin-3-yl]-2-oxopropanoate

ethyl (S)-3-[3-(6-bromo-1H-indol-3-yl)-1-methyl-2-oxoindolin-3-yl]-2-oxopropanoate

Conditions
ConditionsYield
With C53H40N2O2; copper(II) bis(trifluoromethanesulfonate) In ethylbenzene at 20℃; for 24h; Friedel-Crafts Alkylation; Inert atmosphere; enantioselective reaction;99%
6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

1,2,3,4-tetrahydronaphthalen-2-one
530-93-8

1,2,3,4-tetrahydronaphthalen-2-one

6-bromo-3-(3,4-dihydronaphthalen-2-yl)-1H-indole

6-bromo-3-(3,4-dihydronaphthalen-2-yl)-1H-indole

Conditions
ConditionsYield
With L-Tartaric acid; 1,1-Dimethylurea at 70℃; for 3h;99%
6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

C18H28BF3O3Si

C18H28BF3O3Si

C20H22F3NOSi

C20H22F3NOSi

Conditions
ConditionsYield
With (2-dicyclohexylphosphino-2’,6’-diisopropoxy-1,1‘-biphenyl)[2-(2’-methylamino-1,1’-biphenyl)]palladium(II) methanesulfonate; caesium carbonate In tetrahydrofuran; water at 80℃; Suzuki Coupling;99%
6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

isocyanate de chlorosulfonyle
1189-71-5

isocyanate de chlorosulfonyle

6-bromo-1H-indole-3-carbonitrile
224434-83-7

6-bromo-1H-indole-3-carbonitrile

Conditions
ConditionsYield
In N,N-dimethyl-formamide at -50 - 20℃; Inert atmosphere;99%
6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

4-methyl-N-(4-trifluoromethylbenzylidene)-benzenesulfonamide
198012-02-1

4-methyl-N-(4-trifluoromethylbenzylidene)-benzenesulfonamide

(S)-N-((6-bromo-1H-indol-3-yl)(4-(trifluoromethyl)phenyl)methyl)-4-methylbenzenesulfonamide

(S)-N-((6-bromo-1H-indol-3-yl)(4-(trifluoromethyl)phenyl)methyl)-4-methylbenzenesulfonamide

Conditions
ConditionsYield
With (Rp)-4,12-di(4-(3',5'-bis(trifluoromethyl))-phenyl-3-yl)-[2.2]paracyclophane-hydrogenphosphate In toluene at -20℃; for 12h; Molecular sieve; enantioselective reaction;99%
6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

chlorosulfonamide isocyanate

chlorosulfonamide isocyanate

6-bromo-1H-indole-3-carbonitrile
224434-83-7

6-bromo-1H-indole-3-carbonitrile

Conditions
ConditionsYield
In N,N-dimethyl-formamide at -50 - 20℃; for 1.5h; Inert atmosphere;99%
6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

3-(1-phenylvinyl)-1H-indole

3-(1-phenylvinyl)-1H-indole

(R)-3-(1-(1H-indol-3-yl)-1-phenylethyl)-6-bromo-1H-indole

(R)-3-(1-(1H-indol-3-yl)-1-phenylethyl)-6-bromo-1H-indole

Conditions
ConditionsYield
Stage #1: 3-(1-phenylvinyl)-1H-indole With C76H57F12NO6P2 In 1,2-dichloro-ethane at 0℃; for 0.166667h; Molecular sieve;
Stage #2: 6-bromo-1H-indole In 1,2-dichloro-ethane at 0℃; for 24h; Molecular sieve; enantioselective reaction;
99%
6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

1-(1,3-benzothiazol-2-yl)-2,2,2-trifluoroethane-1,1-diol
1033591-96-6

1-(1,3-benzothiazol-2-yl)-2,2,2-trifluoroethane-1,1-diol

(R)-1-(benzo[d]thiazol-2-yl)-1-(6-bromo-1H-indol-3-yl)-2,2,2-trifluoroethan-1-ol

(R)-1-(benzo[d]thiazol-2-yl)-1-(6-bromo-1H-indol-3-yl)-2,2,2-trifluoroethan-1-ol

Conditions
ConditionsYield
With (R)-6,6'-bis(2,4,6-triisopropylphenyl)-1,1'-spirobiindanyl-7,7'-diyl hydrogen phosphate In dichloromethane at 20℃; Friedel-Crafts Alkylation; Molecular sieve; enantioselective reaction;99%
6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

3,4-(methylenedioxy)-benzeneboronic acid
94839-07-3

3,4-(methylenedioxy)-benzeneboronic acid

C15H11NO2

C15H11NO2

Conditions
ConditionsYield
With Ti0.97Pd0.03O1.97; potassium carbonate In water at 100℃; for 6h; Suzuki-Miyaura Coupling;98%
6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

ethyl-3,3,3-trifluoropyruvate
13081-18-0

ethyl-3,3,3-trifluoropyruvate

(S)-ethyl 2-(6-bromo-1H-indol-3-yl)-3,3,3-trifluoro-2-hydroxypropanoate

(S)-ethyl 2-(6-bromo-1H-indol-3-yl)-3,3,3-trifluoro-2-hydroxypropanoate

Conditions
ConditionsYield
With (3aR,11aR,14aS,16bS)-2,2,13,13-tetra-isopropyl-3a,11a,14a,16b-tetrahydro-bis(1,3-dioxolano[4',5':3,4]pyrrolo)[1,2-a:1',2'-a]naphtho[1,2-d:8,7-d']diimidazole; copper(II) bis(trifluoromethanesulfonate) at 25℃; for 1h; Friedel-Crafts Alkylation; Inert atmosphere; Schlenk technique; stereoselective reaction;97.3%
6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

benzenesulfonyl chloride
98-09-9

benzenesulfonyl chloride

1‐(benzenesulfonyl)‐6‐bromo‐1H‐indole
679794-03-7

1‐(benzenesulfonyl)‐6‐bromo‐1H‐indole

Conditions
ConditionsYield
With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate In dichloromethane at 0 - 20℃; for 3h;97%
With tetra(n-butyl)ammonium hydrogensulfate; sodium hydroxide In dichloromethane at 20℃; for 3.16667h; Cooling with ice;95%
With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃;92%
6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

5-bromo-indole-1-carboxylic acid tert-butyl ester
182344-70-3

5-bromo-indole-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With dmap In dichloromethane at 20℃;97%
With dmap In dichloromethane at 20℃; for 1h; Addition;90%
6-bromo-1H-indole
52415-29-9

6-bromo-1H-indole

L-serin
56-45-1

L-serin

(2S)-2-amino-3-(6-bromo-1H-indol-3-yl)propanoic acid
52448-17-6

(2S)-2-amino-3-(6-bromo-1H-indol-3-yl)propanoic acid

Conditions
ConditionsYield
With Pf0A9 enzyme In aq. phosphate buffer; water; dimethyl sulfoxide at 75℃; for 12h; pH=8; Enzymatic reaction;97%
With ammonium sulfate; pyridoxal 5'-phosphate; sodium sulfite In phosphate buffer; dimethyl sulfoxide at 37℃; for 6h; pH=7.8;
Stage #1: 6-bromo-1H-indole; L-serin With acetic anhydride; acetic acid at 73℃; for 3h; Inert atmosphere;
Stage #2: With cobalt(II) chloride; sodium hydroxide In aq. buffer at 37℃; for 48h; pH=8; Enzymatic reaction;

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