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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

Methyl (S)-(+)-3-hydroxybutyrate Manufacturer/High quality/Best price/In stock

Cas:53562-86-0

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Methyl S-3-Hydroxybutanoate supplier in China

Cas:53562-86-0

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

Methyl (S)-(+)-3-Hydroxybutyrate

Cas:53562-86-0

Min.Order:1 Gram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Methyl S-3-Hydroxybutanoate

Cas:53562-86-0

Min.Order:1

Negotiable

Type:Other

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Methyl (S)-(+)-3-hydroxybutyrate

Cas:53562-86-0

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Our advantage:Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scient

TIANFU-CHEM Methyl (S)-(+)-3-hydroxybutyrate

Cas:53562-86-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

Methyl (S)-(-)-3-hydroxybutyrate

Cas:53562-86-0

Min.Order:1 Kilogram

FOB Price: $100.0 / 150.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 53562-86-0 with best quality

Cas:53562-86-0

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Chemical Name Methyl (S)-(+)-3-hydroxybutyrate Synonyms (S)-(+)-Methyl 3-hydroxybutyrate CAS No. 53562-86-0 EINECS No. 258-628-8

Methyl (S)-(-)-3-hydroxybutyrate

Cas:53562-86-0

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Henan Wentao Chemical Product Co., Ltd.

We are leading fine chemicals supplier in China with ISO certificate, Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...) 2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...) 3.OLED

Methyl (S)-(+)-3-hydroxybutyrateCAS NO.:53562-86-0

Cas:53562-86-0

Min.Order:1 Gram

FOB Price: $4.0

Type:Lab/Research institutions

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Butanoic acid,3-hydroxy-, methyl ester, (3S)- 53562-86-0

Cas:53562-86-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Butanoic acid,3-hydroxy-, methyl ester, (3S)-

Cas:53562-86-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

METHYL (S)-(+)-3-HYDROXYBUTYRATE

Cas:53562-86-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

methyl S-3-hydroxybutanoate

Cas:53562-86-0

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

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Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products Methyl (S)-(+)-3-hydroxybutyrate

Cas:53562-86-0

Min.Order:100 Gram

Negotiable

Type:Other

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Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

Methyl (S)-(+)-3-hydroxybutyrate

Cas:53562-86-0

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

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Shanghai Minstar Chemical Co., Ltd

Methyl (S)-(+)-3-hydroxybutyrate Basic information Product Name: Methyl (S)-(+)-3-hydroxybutyrate Synonyms: (S)-(+)-METHYL 3-HYDROXYBUTYRATE;(S)-(+)-3-HYDROXYBUTYRIC ACID METHYL ESTER;(S)-3-HYDROXYBUTYRIC ACID METHYL ESTER;(S)-(+)-3-HYDROXY-N-

Methyl (S)-(+)-3-hydroxybutyrate

Cas:53562-86-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

53562-86-0 CAS NO.53562-86-0

Cas:53562-86-0

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

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Hangzhou ZeErRui Chemical Co., Ltd.

Product name Methyl (S)-(+)-3-hydroxybutyrate Content ≥98% CAS NO. 53562-86-0 Package Structure Formula Appearance:

Methyl (S)-(+)-3-hydroxybutyrate supplier

Cas:53562-86-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service and h

Butanoic acid,3-hydroxy-, methyl ester, (3S)-

Cas:53562-86-0

Min.Order:0

Negotiable

Type:Other

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Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

Methyl (S)-(+)-3-hydroxybutyrate

Cas:53562-86-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe

Methyl (S)-(+)-3-hydroxybutyrate

Cas:53562-86-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

Methyl (S)-(+)-3-hydroxybutyrate

Cas:53562-86-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:colorless transparent liquid Storage:stored in a cool, dry and ventilated place to provent sun and rain Package:25kg/drum, or as per your request. Application:Used as Pharmaceuti

Methyl (S)-(+)-3-hydroxybutyrate

Cas:53562-86-0

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

methyl S-3-hydroxybutanoate cas no. 53562-86-0 98%

Cas:53562-86-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Greenutra Resource Inc

Methyl (S)-(-)-3-hydroxybutyrateAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air

Methyl (S)-(-)-3-hydroxybutyrate

Cas:53562-86-0

Min.Order:0

Negotiable

Type:Trading Company

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Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

Methyl (S)-(-)-3-hydroxybutyrate

Cas:53562-86-0

Min.Order:0

Negotiable

Type:Other

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Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

(S)-3-Hydroxybutanoic acid Methyl ester

Cas:53562-86-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Lonwin Chemical Group Limited

Shanghai Lonwin Chemical company is a subsidiary of Lonwin Industry Group Limited, was established in 2011 and is headquartered in Shanghai, adjacent to China National Convention and Exhibition Center and Hongqiao transportation hub.Lonwinchem is

High Purity Methyl S-3-Hydroxybutanoate 53562-86-0

Cas:53562-86-0

Min.Order:100 Kilogram

FOB Price: $100.0 / 150.0

Type:Other

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GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,or Intermediates,fine chemicals Transportation:air,sea,courier

Methyl-(S)-(+)-3-Hydroxy butryate

Cas:53562-86-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

Conditions
ConditionsYield
With cat; hydrogen In methanol; dichloromethane at 25℃; under 77572.2 Torr; for 48h;100%
With (S)-BiphempRuBr2; hydrogen In methanol at 80℃; under 7600 Torr; for 1h;100%
With hydrogen; [RuCl2(Sax-4,4'-bis(3-diphenylphosphineestra...)(DMF)]n In methanol at 100℃; under 76000 Torr; for 1h; Catalytic hydrogenation;100%
acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

A

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

B

Methyl (R)-3-hydroxybutyrate
3976-69-0

Methyl (R)-3-hydroxybutyrate

Conditions
ConditionsYield
With Ru2Cl4-(S)-(2,2'-bis(diphenylphosphino)-1,1'-binaphthyl)2*NEt3; hydrogen In methanol at 35℃; under 76000.1 Torr; for 48h; Title compound not separated from byproducts;A 100%
B n/a
With <((R)-(1,1'-binaphthyl-2,2'-diyl)bis(diphenylphosphine))RuCl2>2NEt3; hydrogen In methanol at 35℃; under 76000.1 Torr; for 48h; Title compound not separated from byproducts;A n/a
B 100%
With hydrogen; Ru(BICP)Br2 In methanol at 40 - 65℃; under 750.075 - 3750.38 Torr;A n/a
B 95%
acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

A

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

B

Methyl (R)-3-hydroxybutyrate
3976-69-0

Methyl (R)-3-hydroxybutyrate

C

3,3-bismethoxybutyric acid methyl ester
29267-46-7

3,3-bismethoxybutyric acid methyl ester

Conditions
ConditionsYield
With hydrogen; {RuI((R)-2,2'-bis(diphenylphospino)-1,1'-binaphthyl)(p-cymene)}I In methanol at 30℃; under 76000 Torr; for 35h; Product distribution; other: catalysts, solvents, time, pressure, temperatures;A 97%
B n/a
C 3%
acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

A

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

B

3,3-bismethoxybutyric acid methyl ester
29267-46-7

3,3-bismethoxybutyric acid methyl ester

Conditions
ConditionsYield
With hydrogen; {RuI((R)-2,2'-bis(diphenylphospino)-1,1'-binaphthyl)(p-cymene)}I In methanol at 30℃; under 76000 Torr; for 35h;A 97%
B 3%
With hydrogen; {RuI((R)-2,2'-bis(diphenylphospino)-1,1'-binaphthyl)(p-cymene)}I In methanol at 30℃; for 35h; Product distribution; in an autoclave; enantioselectivity; other catalysts;A 96%
B 4%
With hydrogen; {RuI((R)-2,2'-bis(diphenylphospino)-1,1'-binaphthyl)(p-cymene)}I In methanol at 30℃; for 35h; in an autoclave;A 96%
B 4%
methanol
67-56-1

methanol

perennisaponin E
1033766-73-2

perennisaponin E

A

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

B

α-L-Rhamnopyranosyl(1->3)-2β,3β,16α,23-tetrahydroxyolean-12-en-28-saeure-28-O-α-L-rhamnopyranosyl(1->3)-β-D-xylopyranosyl(1->4)-α-L-rhamnopyranosyl(1->2)-β-D-fucopyranosid
121340-61-2

α-L-Rhamnopyranosyl(1->3)-2β,3β,16α,23-tetrahydroxyolean-12-en-28-saeure-28-O-α-L-rhamnopyranosyl(1->3)-β-D-xylopyranosyl(1->4)-α-L-rhamnopyranosyl(1->2)-β-D-fucopyranosid

Conditions
ConditionsYield
With sodium methylate at 20℃; for 3h;A n/a
B 92.3%
methanol
67-56-1

methanol

perennisaponin F
1033766-74-3

perennisaponin F

A

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

B

α-L-Rhamnopyranosyl(1->3)-2β,3β,16α,23-tetrahydroxyolean-12-en-28-saeure-28-O-α-L-rhamnopyranosyl(1->3)-β-D-xylopyranosyl(1->4)-α-L-rhamnopyranosyl(1->2)-β-D-fucopyranosid
121340-61-2

α-L-Rhamnopyranosyl(1->3)-2β,3β,16α,23-tetrahydroxyolean-12-en-28-saeure-28-O-α-L-rhamnopyranosyl(1->3)-β-D-xylopyranosyl(1->4)-α-L-rhamnopyranosyl(1->2)-β-D-fucopyranosid

Conditions
ConditionsYield
With sodium methylate at 20℃; for 3h;A n/a
B 88.8%
methanol
67-56-1

methanol

perennisaponin C
1033766-71-0

perennisaponin C

A

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

B

besysaponin C12

besysaponin C12

Conditions
ConditionsYield
With sodium methylate at 20℃; for 3h;A n/a
B 88.5%
methanol
67-56-1

methanol

perennisaponin B
1033766-70-9

perennisaponin B

A

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

B

polygalacic acid 28-O-α-L-rhamnopyranosyl(1->3)-β-D-xylopyranosyl(1->4)-α-L-rhamnopyranosyl(1->2)-β-D-fucopyranoside

polygalacic acid 28-O-α-L-rhamnopyranosyl(1->3)-β-D-xylopyranosyl(1->4)-α-L-rhamnopyranosyl(1->2)-β-D-fucopyranoside

Conditions
ConditionsYield
With sodium methylate at 20℃; for 3h;A n/a
B 88.4%
methanol
67-56-1

methanol

perennisaponin D
1033766-72-1

perennisaponin D

A

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

B

α-L-Rhamnopyranosyl(1->3)-2β,3β,16α,23-tetrahydroxyolean-12-en-28-saeure-28-O-α-L-rhamnopyranosyl(1->3)-β-D-xylopyranosyl(1->4)-α-L-rhamnopyranosyl(1->2)-β-D-fucopyranosid
121340-61-2

α-L-Rhamnopyranosyl(1->3)-2β,3β,16α,23-tetrahydroxyolean-12-en-28-saeure-28-O-α-L-rhamnopyranosyl(1->3)-β-D-xylopyranosyl(1->4)-α-L-rhamnopyranosyl(1->2)-β-D-fucopyranosid

Conditions
ConditionsYield
With sodium methylate at 20℃; for 3h;A n/a
B 88.4%
methanol
67-56-1

methanol

carbon monoxide
201230-82-2

carbon monoxide

(S)-Propylene oxide
16088-62-3

(S)-Propylene oxide

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

Conditions
ConditionsYield
dicobalt octacarbonyl at 20℃; under 760.051 Torr; for 24h;88%
methyl (2R,3S)-2-bromo-3-hydroxy butanoate
133268-19-6

methyl (2R,3S)-2-bromo-3-hydroxy butanoate

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

Conditions
ConditionsYield
With hydrogen; triethylamine; palladium on activated charcoal In methanol for 4h;85%
(R)-3-Hydroxy-4-((R)-toluene-4-sulfinyl)-butyric acid methyl ester
142176-65-6

(R)-3-Hydroxy-4-((R)-toluene-4-sulfinyl)-butyric acid methyl ester

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

Conditions
ConditionsYield
With nickel81%
Methyl (R)-4-(p-Chlorophenylthio)-3-hydroxybutanoate
114607-87-3

Methyl (R)-4-(p-Chlorophenylthio)-3-hydroxybutanoate

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

Conditions
ConditionsYield
nickel80%
(S)-3-Hydroxybutanoic Acid
6168-83-8

(S)-3-Hydroxybutanoic Acid

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

Conditions
ConditionsYield
In diethyl ether12%
With diethyl ether
In diethyl ether Yield given;
In diethyl ether for 0.166667h; Ambient temperature; Yield given;
l-menthyl (2R,6S)-6-methyl-4-oxo-2-phenyl-1,3-dioxane-2-carboxylate
153080-60-5

l-menthyl (2R,6S)-6-methyl-4-oxo-2-phenyl-1,3-dioxane-2-carboxylate

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

Conditions
ConditionsYield
With hydrogenchloride; potassium hydroxide 1.) methanol, 15 min, 3.) ether; Yield given. Multistep reaction;
methanol
67-56-1

methanol

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

A

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

B

3,3-bismethoxybutyric acid methyl ester
29267-46-7

3,3-bismethoxybutyric acid methyl ester

Conditions
ConditionsYield
With {RuCl((R)-2,2-bis(diphenylphosphino)-1,1'-binaphthyl)(phenyl)}Cl; hydrogen In water at 17℃; under 69873.2 Torr; for 44h;
3-hydroxybutyric acid methyl ester
1487-49-6

3-hydroxybutyric acid methyl ester

A

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

B

Methyl (R)-3-hydroxybutyrate
3976-69-0

Methyl (R)-3-hydroxybutyrate

Conditions
ConditionsYield
With air; cells of Geotrichum candidum IFO5767 In water at 30℃; for 24h; Product distribution;
With pentyl cage-coated capillary column Resolution of racemate;
With homochiral metal-organic cage [Zn3(deprotonated [3+3] macrocyclic Schiff base of trans-1,2-diaminocyclohexane and 4-tert-butyl-2,6-diformylphenol)2] coated capillary column In dichloromethane at 112℃; Resolution of racemate; enantioselective reaction;
Methyl 4-(4-Chlorophenylthio)-3-oxobutanoate
114607-75-9

Methyl 4-(4-Chlorophenylthio)-3-oxobutanoate

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Candida guilliermondii
2: 80 percent / Raney nickel
View Scheme
Methyl 3-oxo-4-<(R)-p-tolylsulfinyl>butyrate
106353-39-3

Methyl 3-oxo-4-<(R)-p-tolylsulfinyl>butyrate

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 60 percent / ZnCl2, HAl(iBu)2 / tetrahydrofuran / -78 °C
2: 81 percent / Raney Nickel
View Scheme
acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

(+-)-5-hydroxy-octan-4-one

(+-)-5-hydroxy-octan-4-one

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 1) LiN(iPr)2 / 1) THF, 0 deg C, 2) THF, -78 deg C, 1 h
2: 60 percent / ZnCl2, HAl(iBu)2 / tetrahydrofuran / -78 °C
3: 81 percent / Raney Nickel
View Scheme
methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-propanoate
1201813-85-5

methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-propanoate

A

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

B

Methyl (R)-3-hydroxybutyrate
3976-69-0

Methyl (R)-3-hydroxybutyrate

Conditions
ConditionsYield
With sodium perborate monohydrate In tetrahydrofuran; methanol; water at 20℃; for 12h; Inert atmosphere;
With sodium perborate In tetrahydrofuran; water at 20℃; Inert atmosphere;
perennisaponin I
1190432-98-4

perennisaponin I

sodium methylate
124-41-4

sodium methylate

A

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

B

α-L-Rhamnopyranosyl(1->3)-2β,3β,16α,23-tetrahydroxyolean-12-en-28-saeure-28-O-α-L-rhamnopyranosyl(1->3)-β-D-xylopyranosyl(1->4)-α-L-rhamnopyranosyl(1->2)-β-D-fucopyranosid
121340-61-2

α-L-Rhamnopyranosyl(1->3)-2β,3β,16α,23-tetrahydroxyolean-12-en-28-saeure-28-O-α-L-rhamnopyranosyl(1->3)-β-D-xylopyranosyl(1->4)-α-L-rhamnopyranosyl(1->2)-β-D-fucopyranosid

Conditions
ConditionsYield
In methanol at 20℃; for 3h;A n/a
B 1.5 mg
perennisaponin J
1190433-12-5

perennisaponin J

sodium methylate
124-41-4

sodium methylate

A

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

B

α-L-Rhamnopyranosyl(1->3)-2β,3β,16α,23-tetrahydroxyolean-12-en-28-saeure-28-O-α-L-rhamnopyranosyl(1->3)-β-D-xylopyranosyl(1->4)-α-L-rhamnopyranosyl(1->2)-β-D-fucopyranosid
121340-61-2

α-L-Rhamnopyranosyl(1->3)-2β,3β,16α,23-tetrahydroxyolean-12-en-28-saeure-28-O-α-L-rhamnopyranosyl(1->3)-β-D-xylopyranosyl(1->4)-α-L-rhamnopyranosyl(1->2)-β-D-fucopyranosid

Conditions
ConditionsYield
In methanol at 20℃; for 3h;A n/a
B 1.5 mg
perennisaponin K
1190433-29-4

perennisaponin K

sodium methylate
124-41-4

sodium methylate

A

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

B

α-L-Rhamnopyranosyl(1->3)-2β,3β,16α,23-tetrahydroxyolean-12-en-28-saeure-28-O-α-L-rhamnopyranosyl(1->3)-β-D-xylopyranosyl(1->4)-α-L-rhamnopyranosyl(1->2)-β-D-fucopyranosid
121340-61-2

α-L-Rhamnopyranosyl(1->3)-2β,3β,16α,23-tetrahydroxyolean-12-en-28-saeure-28-O-α-L-rhamnopyranosyl(1->3)-β-D-xylopyranosyl(1->4)-α-L-rhamnopyranosyl(1->2)-β-D-fucopyranosid

Conditions
ConditionsYield
In methanol at 20℃; for 3h;A n/a
B 1.5 mg
perennisaponin L
1190433-46-5

perennisaponin L

sodium methylate
124-41-4

sodium methylate

A

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

B

α-L-Rhamnopyranosyl(1->3)-2β,3β,16α,23-tetrahydroxyolean-12-en-28-saeure-28-O-α-L-rhamnopyranosyl(1->3)-β-D-xylopyranosyl(1->4)-α-L-rhamnopyranosyl(1->2)-β-D-fucopyranosid
121340-61-2

α-L-Rhamnopyranosyl(1->3)-2β,3β,16α,23-tetrahydroxyolean-12-en-28-saeure-28-O-α-L-rhamnopyranosyl(1->3)-β-D-xylopyranosyl(1->4)-α-L-rhamnopyranosyl(1->2)-β-D-fucopyranosid

Conditions
ConditionsYield
In methanol at 20℃; for 3h;A n/a
B 1.5 mg
perennisaponin M
1190433-62-5

perennisaponin M

sodium methylate
124-41-4

sodium methylate

A

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

B

α-L-Rhamnopyranosyl(1->3)-2β,3β,16α,23-tetrahydroxyolean-12-en-28-saeure-28-O-α-L-rhamnopyranosyl(1->3)-β-D-xylopyranosyl(1->4)-α-L-rhamnopyranosyl(1->2)-β-D-fucopyranosid
121340-61-2

α-L-Rhamnopyranosyl(1->3)-2β,3β,16α,23-tetrahydroxyolean-12-en-28-saeure-28-O-α-L-rhamnopyranosyl(1->3)-β-D-xylopyranosyl(1->4)-α-L-rhamnopyranosyl(1->2)-β-D-fucopyranosid

Conditions
ConditionsYield
In methanol at 20℃; for 3h;A n/a
B 1.5 mg
3-Hydroxybutyric acid
300-85-6, 625-71-8

3-Hydroxybutyric acid

A

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

B

Methyl (R)-3-hydroxybutyrate
3976-69-0

Methyl (R)-3-hydroxybutyrate

Conditions
ConditionsYield
In diethyl ether; water; ethyl acetate for 0.25h;
(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: bis[2-(diphenylphosphino)phenyl] ether; copper(l) chloride; sodium t-butanolate / tetrahydrofuran; methanol
2: Candida antarctica lipase immobilized on acrylic resin / hexane / 24 h / 70 °C / Sealed tube; Enzymatic reaction
3: sodium perborate tetrahydrate / tetrahydrofuran; water / 1 h / 20 °C
View Scheme
(S)-methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butanoate
1185248-82-1

(S)-methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butanoate

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

Conditions
ConditionsYield
With sodium perborate tetrahydrate In tetrahydrofuran; water at 20℃; for 1h;
(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

(3S)-3-(tert-butyldimethylsilyloxy)butanoic acid methyl ester
148555-62-8

(3S)-3-(tert-butyldimethylsilyloxy)butanoic acid methyl ester

Conditions
ConditionsYield
With 1H-imidazole; dmap In N,N-dimethyl-formamide at 0 - 20℃; for 3h; Inert atmosphere;100%
With 1H-imidazole In N,N-dimethyl-formamide at 70℃; for 8h;99%
With 1H-imidazole In N,N-dimethyl-formamide at 20℃;98%
(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

tert-butylchlorodiphenylsilane
58479-61-1

tert-butylchlorodiphenylsilane

methyl (3S)-3-{[tert-butyl(diphenyl)silyl]oxy}butanoate
215444-96-5

methyl (3S)-3-{[tert-butyl(diphenyl)silyl]oxy}butanoate

Conditions
ConditionsYield
With 1H-imidazole In N,N-dimethyl-formamide100%
With 1H-imidazole In N,N-dimethyl-formamide at 53℃; for 18h;100%
With 1H-imidazole In N,N-dimethyl-formamide at 0 - 20℃;99%
(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

(S)-3-Methanesulfonyloxy-butyric acid methyl ester

(S)-3-Methanesulfonyloxy-butyric acid methyl ester

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0℃;99%
With triethylamine In dichloromethane for 1h; Ambient temperature;91%
3,4-dihydro-2H-pyran
110-87-2

3,4-dihydro-2H-pyran

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

(S)-3-(Tetrahydro-pyran-2-yloxy)-butyric acid methyl ester

(S)-3-(Tetrahydro-pyran-2-yloxy)-butyric acid methyl ester

Conditions
ConditionsYield
With hydrogen cation97%
(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

O-(4-methoxybenzyl)-trichloroacetimidate
89238-99-3

O-(4-methoxybenzyl)-trichloroacetimidate

methyl (S)-3-(4-methoxybenzyloxy)butanoate
350848-03-2

methyl (S)-3-(4-methoxybenzyloxy)butanoate

Conditions
ConditionsYield
With 10-camphorsulfonic acid In dichloromethane at 20℃; for 7h;95%
With D,L-camphorsulfonic acid In dichloromethane at 20℃; for 12h; Inert atmosphere;70%
With camphor-10-sulfonic acid In dichloromethane
acetic acid tert-butyl ester
540-88-5

acetic acid tert-butyl ester

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

(+)-(5S)-hydroxy-5-oxo-3-hexanoate de tert-butyle
97037-72-4, 125404-66-2, 125404-65-1

(+)-(5S)-hydroxy-5-oxo-3-hexanoate de tert-butyle

Conditions
ConditionsYield
With lithium diisopropyl amide In tetrahydrofuran at -78 - -15℃;94%
Stage #1: acetic acid tert-butyl ester With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 0.333333h;
Stage #2: (S)-3-hydroxybutyric acid methyl ester In tetrahydrofuran at -50 - -15℃; Claisen condensation;
93%
Stage #1: acetic acid tert-butyl ester With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 0.333333h;
Stage #2: (S)-3-hydroxybutyric acid methyl ester In tetrahydrofuran at -50℃; for 2h;
87%
With lithium diisopropyl amide
With lithium diisopropyl amide In tetrahydrofuran
(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

1,3-butanediol
24621-61-2

1,3-butanediol

Conditions
ConditionsYield
With lithium aluminium tetrahydride In diethyl ether for 1h; Ambient temperature;91%
With hydrogen; Nishimura catalyst <(45.9% Rh/19.9% Pt) oxide> In methanol at 25℃; under 75007.5 Torr;
With lithium borohydride
(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

O-benzyl 2,2,2-trichloroacetimidate
81927-55-1

O-benzyl 2,2,2-trichloroacetimidate

(S)-3-(benzyloxy)butanoic acid methyl ester
90124-15-5

(S)-3-(benzyloxy)butanoic acid methyl ester

Conditions
ConditionsYield
With trifluorormethanesulfonic acid In dichloromethane at 20℃; for 24h;89%
With trifluorormethanesulfonic acid In hexane; dichloromethane at 0℃;
With trifluorormethanesulfonic acid In hexane; dichloromethane for 4h; Ambient temperature;
With cyclohexane In dichloromethane; trifluorormethanesulfonic acid
(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

N,O-dimethylhydroxylamine*hydrochloride
6638-79-5

N,O-dimethylhydroxylamine*hydrochloride

(S)-3-hydroxy-N-methoxy-N-methylbutanamide
474825-97-3

(S)-3-hydroxy-N-methoxy-N-methylbutanamide

Conditions
ConditionsYield
With isopropylmagnesium chloride In tetrahydrofuran at -30 - 0℃; for 3.5h;89%
(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

trifluoromethylsulfonic anhydride
358-23-6

trifluoromethylsulfonic anhydride

(S)-3-(Trifluormethylsulfonyloxy)buttersaeure-methylester
112424-25-6

(S)-3-(Trifluormethylsulfonyloxy)buttersaeure-methylester

Conditions
ConditionsYield
With pyridine In dichloromethane at 40℃; for 2h;87%
(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

(R)-methoxytrifluoromethylphenylacetyl chloride
20445-33-4, 39637-99-5

(R)-methoxytrifluoromethylphenylacetyl chloride

methyl (3S)-3-<(S)-(-)-α-methoxy-α-(trifluoromethyl)phenylacetyl>butyrate

methyl (3S)-3-<(S)-(-)-α-methoxy-α-(trifluoromethyl)phenylacetyl>butyrate

Conditions
ConditionsYield
With pyridine In tetrachloromethane for 12h; Ambient temperature;86%
(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

prenyl bromide
870-63-3

prenyl bromide

(S)-methyl 2-((S)-1-hydroxyethyl)-5-methylhex-4-enoate

(S)-methyl 2-((S)-1-hydroxyethyl)-5-methylhex-4-enoate

Conditions
ConditionsYield
Stage #1: (S)-3-hydroxybutyric acid methyl ester With lithium diisopropyl amide In tetrahydrofuran at -30℃; for 1.75h;
Stage #2: prenyl bromide In tetrahydrofuran; 1,2-dimethoxyethane at -78 - -60℃; for 2.75h;
86%
Stage #1: (S)-3-hydroxybutyric acid methyl ester With lithium diisopropyl amide In tetrahydrofuran at -30℃; for 1.75h;
Stage #2: prenyl bromide In tetrahydrofuran; 1,2-dimethoxyethane at -78 - 60℃; for 2.5h;
86%
Stage #1: (S)-3-hydroxybutyric acid methyl ester With lithium diisopropyl amide In tetrahydrofuran at -78 - -30℃; for 1.75h;
Stage #2: prenyl bromide In tetrahydrofuran; 1,2-dimethoxyethane at -60℃; for 2.75h;
86%
Stage #1: (S)-3-hydroxybutyric acid methyl ester With n-butyllithium; diisopropylamine In tetrahydrofuran; hexane at -50 - -30℃; for 1.75h;
Stage #2: prenyl bromide In tetrahydrofuran; 1,2-dimethoxyethane; hexane at -78 - 20℃; for 2.75h;
86%
Stage #1: (S)-3-hydroxybutyric acid methyl ester With lithium diisopropyl amide In tetrahydrofuran at -70℃; for 1h; Inert atmosphere;
Stage #2: prenyl bromide With N,N,N,N,N,N-hexamethylphosphoric triamide In tetrahydrofuran at -70 - -10℃; for 3h; Inert atmosphere; diastereoselective reaction;
81%
1-iodo-2-methyl-2-propene
3756-30-7

1-iodo-2-methyl-2-propene

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

(2S,1'S)-2-(1-hydroxyethyl)-pent-4-enoate methyle
123408-35-5

(2S,1'S)-2-(1-hydroxyethyl)-pent-4-enoate methyle

Conditions
ConditionsYield
80%
(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

methyl iodide
74-88-4

methyl iodide

methyl (2S,3S)-3-hydroxy-2-methylbutanoate
66767-60-0

methyl (2S,3S)-3-hydroxy-2-methylbutanoate

Conditions
ConditionsYield
Stage #1: (S)-3-hydroxybutyric acid methyl ester With n-butyllithium; diisopropylamine In tetrahydrofuran; hexane at -78℃; for 0.5h;
Stage #2: methyl iodide at -78℃; for 1.5h;
79%
With 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; lithium diisopropyl amide In tetrahydrofuran at -78℃;78%
Stage #1: (S)-3-hydroxybutyric acid methyl ester With lithium diisopropyl amide In tetrahydrofuran; hexane at -78℃; for 0.5h; Inert atmosphere;
Stage #2: methyl iodide In tetrahydrofuran; hexane at -78℃; for 1.5h; Inert atmosphere;
77%
(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

(4R,5S)-4-benzyloxy-5-tert-butyldimethylsilyloxy-2(E)-hexenoic acid
294198-49-5

(4R,5S)-4-benzyloxy-5-tert-butyldimethylsilyloxy-2(E)-hexenoic acid

methyl (3S,8R,9S)-8-benzyloxy-9-tert-butyldimethylsiloxy-3-methyl-5-oxo-4-oxadeca (6E)-enoate
473555-54-3

methyl (3S,8R,9S)-8-benzyloxy-9-tert-butyldimethylsiloxy-3-methyl-5-oxo-4-oxadeca (6E)-enoate

Conditions
ConditionsYield
With dmap; (1S)-10-camphorsulfonic acid; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 48h; Keck condensation;75%
(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

dimethyl (2S,2E)-2-((3-(4-hydroxy-3,5-dimethoxyphenyl)acryloyl)oxy)succinate
1270043-91-8

dimethyl (2S,2E)-2-((3-(4-hydroxy-3,5-dimethoxyphenyl)acryloyl)oxy)succinate

C22H34O7Si

C22H34O7Si

Conditions
ConditionsYield
With dmap In dichloromethane at 20℃;73.7%
(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

p-toluenesulfonyl chloride
98-59-9

p-toluenesulfonyl chloride

(3S)-methyl 3-(p-toluenesulfonyl)butyrate
91366-13-1

(3S)-methyl 3-(p-toluenesulfonyl)butyrate

Conditions
ConditionsYield
In pyridine at -5 - 0℃; for 48h;70%
With pyridine Ambient temperature;
With pyridine; triethylamine In toluene at 0 - 20℃; Inert atmosphere;

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