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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

5-Bromoindazole Manufacturer/High quality/Best price/In stock

Cas:53857-57-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 5-Bromo-1H-Indazole supplier in China

Cas:53857-57-1

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Henan Allgreen Chemical Co.,Ltd

he company has advanced technology, as well as a large number of excellent R & D team, to provide customers from the grams to one hundred kilograms and tons of high-quality products, competitive prices and quality se T rvice Appearance:Whit

5-BroMoindazole

Cas:53857-57-1

Min.Order:1 Gram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 5-Bromo-1H-Indazole

Cas:53857-57-1

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price OLED 99% 53857-57-1 5-BroMoindazole Manufacturer

Cas:53857-57-1

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermedi

5-Bromoindazole

Cas:53857-57-1

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

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ANQING CHICO PHARMACEUTICAL CO.,LTD.

High quality. Factory supply. In stock. Best price.1.Quick response within 24 hours;2.Best quality in your requirement;?3.We pay more attention on delivery time, and usually ship on time;4.Under the premise of safety and effectiveness, we can produce

5-Bromoindazole

Cas:53857-57-1

Min.Order:0

Negotiable

Type:Trading Company

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

5-Bromoindazole

Cas:53857-57-1

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

5-Bromoindazole

Cas:53857-57-1

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

chengdu and import and export trade co., LTD., who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do res

5-bromo-1H-indazole

Cas:53857-57-1

Min.Order:1 Kilogram

FOB Price: $120.0 / 150.0

Type:Trading Company

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Henan Tianfu Chemical Co., Ltd.

5-Bromoindazole Basic information Product Name: 5-Bromoindazole Synonyms: 5-BROMO-1H-INDAZOLE;5-BROMOINDAZOLE;4-BROMOIMIDAZOLE;5-Bromo-1H-indazole 97%;5-Bromo-1H-in

5-Bromoindazole 53857-57-1

Cas:53857-57-1

Min.Order:0 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Manufacturer supply CAS 53857-57-1 with best quality

Cas:53857-57-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

5-Bromoindazole/ LIDE PHARMA- Factory supply / Best price

Cas:53857-57-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Sinotech Import&Export Corporation

Product Name 5-Bromoindazole CAS 53857-57-1 MF C7H5BrN2 MW 197.03

5-Bromoindazole CAS: 53857-57-1

Cas:53857-57-1

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

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Henan Wentao Chemical Product Co., Ltd.

We are leading fine chemicals supplier in China with ISO certificate, Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...) 2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...) 3.OLED

1H-Indazole, 5-bromo-CAS NO.:53857-57-1

Cas:53857-57-1

Min.Order:1 Gram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:Powder Storage:Store in sealed containers at cool & dry pla

Pharmaceutical Intermediates 5-Bromoindazole CAS 53857-57-1

Cas:53857-57-1

Min.Order:100 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

5-Bromoindazole 53857-57-1

Cas:53857-57-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 5-Bromoindazole CAS: 53857-57-1 MF: C7H5BrN2 MW: 197.03 EINECS: Mol File: 53857-57-1.mol 5-Bromoindazole Structure 5-Bromoindazole Chemical Properties Melting point 131-135 °C(lit.) Boiling point 333.8&p

5-bromoindazole

Cas:53857-57-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

5-Bromoindazole

Cas:53857-57-1

Min.Order:1 Metric Ton

FOB Price: $22.0 / 30.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

5-Bromoindazole CAS:53857-57-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermedi

5-Bromoindazole CAS:53857-57-1

Cas:53857-57-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

5-Bromoindazole

Cas:53857-57-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

5-Bromo-1H-Indazole

Cas:53857-57-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Triumph International Development Limilted

Lorcaserin(856681-05-5)is an orally administered agent and a selective 5-HT2C receptor agonist for the treatment of obesity. It had been approved for marketing in US by FDA on 27 June in 2012. In clinical studies, lorcaserin h

5-Bromoindazole

Cas:53857-57-1

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

5-bromo-1H-indazole

Cas:53857-57-1

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

5-Bromo-1H-indazole

Cas:53857-57-1

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

5-Bromoindazole

Cas:53857-57-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

5-Bromoindazole

Cas:53857-57-1

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High purity 5-Bromoindazole

Cas:53857-57-1

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

5-BromoindazoleAppearance:white powder Storage:Store in dry, dark and ventilated place Package:according to customers' requirements Application:chemical research Transportation:By air(EMS or EUB or FedEx or TNT ect...) or by sea(FOB or CIF or CNF ect

5-Bromoindazole

Cas:53857-57-1

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Siwei Development Group Ltd.

Product name: 5-Bromoindazole CAS No.:53857-57-1 Molecule Formula: C7H5BrN2 Molecule Weight:197.03 Purity: 99.0% Package: 25kg/drum Description:White to off-white powder Manufacture Standards:Enterprise Standard TESTING ITEMS

Lower Price 5-Bromoindazole

Cas:53857-57-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

tert-butyl (4-bromo-2-methylphenyl)azo sulfide

tert-butyl (4-bromo-2-methylphenyl)azo sulfide

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

Conditions
ConditionsYield
With potassium tert-butylate In dimethyl sulfoxide for 1.5h; Ambient temperature;98%
5-bromo-2-fluorobenzaldehyde
93777-26-5

5-bromo-2-fluorobenzaldehyde

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

Conditions
ConditionsYield
With hydrazine hydrate at 100℃; for 12h;96%
With hydrazine at 100℃;50%
With hydrazine hydrate In 1,2-dimethoxyethane for 15h; Heating;45%
4-Bromo-2-methylaniline
583-75-5

4-Bromo-2-methylaniline

isopentyl nitrite
110-46-3

isopentyl nitrite

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

Conditions
ConditionsYield
With hydrogenchloride; sodium hydroxide; potassium acetate; acetic anhydride In n-heptane; chloroform; water; ethyl acetate94%
5-bromo-1-(phenylsulfonyl)-1H-indazole

5-bromo-1-(phenylsulfonyl)-1H-indazole

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

Conditions
ConditionsYield
With diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; Cu(dq)((rac)-2,2′-bis(diphenylphosphino)-1,1′-binaphthalene)BF4; N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃; for 24h; Inert atmosphere; Irradiation;89%
3,5-dibromoindazole
40598-76-3

3,5-dibromoindazole

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

Conditions
ConditionsYield
With methanol; magnesium at 20℃; chemoselective reaction;84%
With phosphorus; hydrogen iodide at 110℃;
5-bromo-1-tosyl-1H-indazole

5-bromo-1-tosyl-1H-indazole

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl acetamide at 60℃; for 2h; Inert atmosphere;82%
4-bromo-2-methylbenzenediazonium tetrafluoroborate

4-bromo-2-methylbenzenediazonium tetrafluoroborate

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

Conditions
ConditionsYield
With 18-crown-6 ether; potassium acetate In chloroform at 20℃; for 2h;80%
With potassium acetate; 18-crown-6 ether In chloroform at 20℃; for 2h;65%
With 18-crown-6 ether; potassium acetate In chloroform at 20℃;60%
4-Bromo-2-methylaniline
583-75-5

4-Bromo-2-methylaniline

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

Conditions
ConditionsYield
With acetic acid; sodium nitrite In water at 20℃; for 5h;61%
Stage #1: 4-Bromo-2-methylaniline With acetic anhydride In chloroform at 0 - 40℃; for 1h;
Stage #2: With potassium acetate; isopentyl nitrite In chloroform for 18h; Heating / reflux;
Stage #3: With hydrogenchloride In water at 50℃; for 2h;
60%
Stage #1: 4-Bromo-2-methylaniline With tetrafluoroboric acid; sodium nitrite In water at 0℃;
Stage #2: With 18-crown-6 ether; potassium acetate In chloroform at 20℃; Further stages.;
Multi-step reaction with 2 steps
1.1: water / 0.25 h / 20 °C
1.2: 0 - 5 °C
2.1: 18-crown-6 ether; potassium acetate / chloroform / 2 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: sodium acetate / toluene / 0.67 h / 85 °C
2: toluene / 4.25 h / 65 °C
View Scheme
3-amino-5-bromo-1H-indazole
61272-71-7

3-amino-5-bromo-1H-indazole

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

Conditions
ConditionsYield
With nitrous acid isobutyl ester; hypophosphorous acid In ethanol; water at 0 - 20℃; for 3h;40%
5-bromobenzopyrazole-3-carboxylic acid
1077-94-7

5-bromobenzopyrazole-3-carboxylic acid

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

Conditions
ConditionsYield
at 320℃;
3-Diazo-3H-indazol
2596-89-6

3-Diazo-3H-indazol

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

Conditions
ConditionsYield
With hydrogen bromide
acetic acid-(4-bromo-2-methyl-N-nitroso-anilide)
861796-22-7

acetic acid-(4-bromo-2-methyl-N-nitroso-anilide)

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

Conditions
ConditionsYield
With benzene
acetic acid-(4-bromo-2-methyl-N-nitroso-anilide)
861796-22-7

acetic acid-(4-bromo-2-methyl-N-nitroso-anilide)

benzene
71-43-2

benzene

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

Conditions
ConditionsYield
at 60℃;
5-bromo-indazole-carboxylic acid-(3)

5-bromo-indazole-carboxylic acid-(3)

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

5-bromo-1-(2-nitro-benzoyl)-1H-indazole

5-bromo-1-(2-nitro-benzoyl)-1H-indazole

alcoholic KOH-solution

alcoholic KOH-solution

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

hydrogen iodide
10034-85-2

hydrogen iodide

3,5-dibromoindazole
40598-76-3

3,5-dibromoindazole

red phosphorus

red phosphorus

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

Conditions
ConditionsYield
at 110℃;
5-bromobenzopyrazole-3-carboxylic acid
1077-94-7

5-bromobenzopyrazole-3-carboxylic acid

water
7732-18-5

water

A

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

B

methylammonium carbonate
15719-64-9, 15719-76-3, 97762-63-5

methylammonium carbonate

Conditions
ConditionsYield
at 200℃;
3-Diazo-3H-indazol
2596-89-6

3-Diazo-3H-indazol

hydrogen bromide
10035-10-6, 12258-64-9

hydrogen bromide

A

benzimidazole
271-44-3

benzimidazole

B

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

C

3-bromo-1H-indazole
40598-94-5

3-bromo-1H-indazole

D

3,5-dibromoindazole
40598-76-3

3,5-dibromoindazole

5-bromo-2-fluoro-benzaldehyde O-methyl-oxime

5-bromo-2-fluoro-benzaldehyde O-methyl-oxime

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

Conditions
ConditionsYield
With hydrazine In 1,2-dimethoxyethane Heating;
With hydrazine hydrate Reflux;
With hydrazine hydrate Reflux;
tert.-butylnitrite
540-80-7

tert.-butylnitrite

4'-bromo-2'-methylacetanilide
24106-05-6

4'-bromo-2'-methylacetanilide

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

Conditions
ConditionsYield
In toluene at 65℃; for 4.25h;
4'-bromo-2'-methylacetanilide
24106-05-6

4'-bromo-2'-methylacetanilide

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: glacial acetic acid / Einleiten von nitrosen Gasen
2: benzene
View Scheme
Multi-step reaction with 3 steps
1.1: hydrogenchloride / ethanol / 3 h / Reflux
1.2: 0.5 h / 20 °C
2.1: water / 0.25 h / 20 °C
2.2: 0 - 5 °C
3.1: 18-crown-6 ether; potassium acetate / chloroform / 2 h / 20 °C
View Scheme
3-bromo-1H-indazole
40598-94-5

3-bromo-1H-indazole

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: glacial acetic acid / durch Bromierung
2: concentrated hydriodic acid; red phosphorus / 110 °C
View Scheme
aqueous concentrated HCl

aqueous concentrated HCl

ammonium tetrafluroborate
13826-83-0

ammonium tetrafluroborate

4-Bromo-2-methylaniline
583-75-5

4-Bromo-2-methylaniline

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

Conditions
ConditionsYield
With potassium acetate; sodium nitrite In chloroform; acetic acid
With potassium acetate; sodium nitrite In chloroform; acetic acid
With potassium acetate; sodium nitrite In chloroform; acetic acid
ammonium tetrafluroborate
13826-83-0

ammonium tetrafluroborate

4-Bromo-2-methylaniline
583-75-5

4-Bromo-2-methylaniline

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

Conditions
ConditionsYield
With hydrogenchloride; potassium acetate; acetic acid; sodium nitrite In chloroform; water
5-bromo-2-fluorobenzaldehyde
93777-26-5

5-bromo-2-fluorobenzaldehyde

A

5-bromo-2-fluorotoluene
51437-00-4

5-bromo-2-fluorotoluene

B

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

Conditions
ConditionsYield
With hydrazine Inert atmosphere; Reflux;
o-toluidine
95-53-4

o-toluidine

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: 2 h / 110 - 115 °C
2.1: bromine; acetic acid / 1.5 h / 50 °C
3.1: hydrogenchloride / ethanol / 3 h / Reflux
3.2: 0.5 h / 20 °C
4.1: water / 0.25 h / 20 °C
4.2: 0 - 5 °C
5.1: 18-crown-6 ether; potassium acetate / chloroform / 2 h / 20 °C
View Scheme
N-(2-methylphenyl)acetamide
120-66-1

N-(2-methylphenyl)acetamide

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: bromine; acetic acid / 1.5 h / 50 °C
2.1: hydrogenchloride / ethanol / 3 h / Reflux
2.2: 0.5 h / 20 °C
3.1: water / 0.25 h / 20 °C
3.2: 0 - 5 °C
4.1: 18-crown-6 ether; potassium acetate / chloroform / 2 h / 20 °C
View Scheme
N-methoxylamine hydrochloride
593-56-6

N-methoxylamine hydrochloride

5-bromo-2-fluorobenzaldehyde
93777-26-5

5-bromo-2-fluorobenzaldehyde

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

Conditions
ConditionsYield
Stage #1: N-methoxylamine hydrochloride; 5-bromo-2-fluorobenzaldehyde With potassium carbonate In 1,2-dimethoxyethane at 40℃;
Stage #2: With hydrazine In 1,2-dimethoxyethane Reflux;
5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

5-bromo-3-iodo-1H-indazole
459133-66-5

5-bromo-3-iodo-1H-indazole

Conditions
ConditionsYield
With iodine; potassium hydroxide In N,N-dimethyl-formamide at 20℃; for 3h;100%
Stage #1: 5-bromo-1H-indazole With potassium tert-butylate In tetrahydrofuran at 0℃;
Stage #2: With iodine In tetrahydrofuran at 0 - 20℃;
99%
With iodine; potassium hydroxide In N,N-dimethyl-formamide at 20℃; for 2h; Inert atmosphere;97.9%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

tert-butyl 5-bromo-1H-indazole-1-carboxylate
651780-02-8

tert-butyl 5-bromo-1H-indazole-1-carboxylate

Conditions
ConditionsYield
With dmap In dichloromethane at 20℃;100%
With dmap; triethylamine In acetonitrile for 3h;99%
With dmap In acetonitrile at 23℃; for 0.25h; Inert atmosphere;99%
5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

bis(pinacol)diborane
73183-34-3

bis(pinacol)diborane

5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
862723-42-0

5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole

Conditions
ConditionsYield
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate In N,N-dimethyl-formamide at 100℃; Inert atmosphere;100%
With potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride In N,N-dimethyl-formamide at 90℃; for 24h;84%
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate In 1,4-dioxane at 90℃; for 24h; Inert atmosphere;81%
5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

5-iodo-1H-indazole
55919-82-9

5-iodo-1H-indazole

Conditions
ConditionsYield
With sodium iodide; trans-N,N'-dimethyl-1,2-cyclohexyldiamine; copper(l) iodide In 1,4-dioxane at 110℃; for 68h;100%
5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

ethyl vinyl ether
109-92-2

ethyl vinyl ether

5-bromo-1-(1-ethoxyethyl)-1H-indazole
1178903-22-4

5-bromo-1-(1-ethoxyethyl)-1H-indazole

Conditions
ConditionsYield
With toluene-4-sulfonic acid In dichloromethane for 18h; regioselective reaction;99%
5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

N,2-dimethylaniline
611-21-2

N,2-dimethylaniline

N-methyl-N-(o-tolyl)-1H-indazol-5-amine
1248590-76-2

N-methyl-N-(o-tolyl)-1H-indazol-5-amine

Conditions
ConditionsYield
With chloro-(2-dicyclohexylphosphino-2′,6′-diisopropoxy-1,1′-biphenyl)[2-(2-aminoethyl)phenyl]palladium(II); lithium hexamethyldisilazane; ruphos In tetrahydrofuran at 65℃; for 4h; Inert atmosphere; Sealed vial;99%
With [Pd(RuPhos)(dvtms)]; lithium hexamethyldisilazane In tetrahydrofuran at 65℃; for 16h; Buchwald-Hartwig Coupling; Sealed tube;
3,4-dihydro-2H-pyran
110-87-2

3,4-dihydro-2H-pyran

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

5-bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole

5-bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole

Conditions
ConditionsYield
With toluene-4-sulfonic acid In dichloromethane for 1h; regioselective reaction;98.2%
With toluene-4-sulfonic acid In toluene at 15 - 75℃; for 2h; Inert atmosphere;98%
With toluene-4-sulfonic acid In dichloromethane at 20℃; for 3h;97%
5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

(2-trimethylethylsilylethoxy)methyl chloride
76513-69-4

(2-trimethylethylsilylethoxy)methyl chloride

5-bromo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-indazole
894808-05-0

5-bromo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-indazole

Conditions
ConditionsYield
Stage #1: 5-bromo-1H-indazole With lithium hexamethyldisilazane In tetrahydrofuran at -78℃; for 0.5h;
Stage #2: (2-trimethylethylsilylethoxy)methyl chloride In tetrahydrofuran at 20℃; for 16h;
98%
With potassium hydroxide; tetrabutylammomium bromide In dichloromethane; water at 0 - 20℃; for 3h;81%
With tetrabutylammomium bromide; sodium hydroxide In dichloromethane; water for 3h; Inert atmosphere;81%
Stage #1: 5-bromo-1H-indazole With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 0.5h;
Stage #2: (2-trimethylethylsilylethoxy)methyl chloride In tetrahydrofuran; mineral oil at 20℃; for 3h;
70%
Stage #1: 5-bromo-1H-indazole With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; for 0.5h; Inert atmosphere;
Stage #2: (2-trimethylethylsilylethoxy)methyl chloride In N,N-dimethyl-formamide at 0℃; for 2h;
63%
5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

1-(4-chlorophenyl)piperazine hydrochloride
13078-12-1

1-(4-chlorophenyl)piperazine hydrochloride

5-(4-(4-chlorophenyl)piperazin-1-yl)-1H-indazole
1248590-77-3

5-(4-(4-chlorophenyl)piperazin-1-yl)-1H-indazole

Conditions
ConditionsYield
With RuPhos palladacycle; lithium hexamethyldisilazane; ruphos In tetrahydrofuran at 65℃; for 4h; Inert atmosphere; Sealed vial;98%
5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

p-toluenesulfonyl chloride
98-59-9

p-toluenesulfonyl chloride

5-bromo-1-tosyl-1H-indazole

5-bromo-1-tosyl-1H-indazole

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 50℃; Reagent/catalyst; Temperature;97%
With triethylamine In acetonitrile at 50℃; for 8h;93%
3-Dimethylaminopropanethiol
42302-17-0

3-Dimethylaminopropanethiol

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

3-((1H-indazol-5-yl)thio)-N,N-dimethylpropan-1-amine

3-((1H-indazol-5-yl)thio)-N,N-dimethylpropan-1-amine

Conditions
ConditionsYield
With lithium hexamethyldisilazane In tetrahydrofuran at 120℃; for 16h; Inert atmosphere;97%
5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

dimethyl amine
124-40-3

dimethyl amine

N,N-dimethyl-1H-indazol-5-amine

N,N-dimethyl-1H-indazol-5-amine

Conditions
ConditionsYield
With RuPhos palladacycle; lithium hexamethyldisilazane; ruphos In tetrahydrofuran at 65℃; for 4h; Inert atmosphere; Sealed vial;96%
5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

phenylboronic acid
98-80-6

phenylboronic acid

5-bromo-1-phenyl-1H-indazole
861905-18-2

5-bromo-1-phenyl-1H-indazole

Conditions
ConditionsYield
With pyridine; oxygen; copper diacetate In dichloromethane at 15℃; for 12h;96%
5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

Acetic formic anhydride
2258-42-6

Acetic formic anhydride

1H-indazole-5-carboxylic acid
61700-61-6

1H-indazole-5-carboxylic acid

Conditions
ConditionsYield
Stage #1: 5-bromo-1H-indazole; formyl acetic anhydride With 1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 90℃; for 2h; Inert atmosphere;
Stage #2: With hydrogenchloride In water pH=Ca. 4 - 6;
95%
3-mercaptopropionic acid ethyl ester
5466-06-8

3-mercaptopropionic acid ethyl ester

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

ethyl 3-((1H-indazol-5-yl)thio)propionate

ethyl 3-((1H-indazol-5-yl)thio)propionate

Conditions
ConditionsYield
With tris-(dibenzylideneacetone)dipalladium(0); N-ethyl-N,N-diisopropylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene In 1,4-dioxane at 100℃; for 2h; Inert atmosphere;95%
5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

[2-(2-fluorophenyl)ethyl]amine
52721-69-4

[2-(2-fluorophenyl)ethyl]amine

N-(2-fluorophenethyl)-1H-indazol-5-amine
1248590-86-4

N-(2-fluorophenethyl)-1H-indazol-5-amine

Conditions
ConditionsYield
With dicyclohexyl-(2′,4′,6′-triisopropyl-3,6-dimethoxy-[1,1′-biphenyl]-2-yl)phosphine; chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2’,4’,6’-triisopropyl-1,1’-biphenyl] [2-(2-aminoethyl)phenyl]palladium(II); lithium hexamethyldisilazane In tetrahydrofuran at 65℃; for 4h; Inert atmosphere; Sealed vial;94%
3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

C14H12N2OS

C14H12N2OS

Conditions
ConditionsYield
With C31H49O2P*C12H10N(1-)*CH3O3S(1-)*Pd(2+)*CH2Cl2; lithium hexamethyldisilazane In tetrahydrofuran at 20℃;93%
5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

acetic anhydride
108-24-7

acetic anhydride

1-(5-bromo-1H-indazol-1-yl)ethanone
152626-92-1

1-(5-bromo-1H-indazol-1-yl)ethanone

Conditions
ConditionsYield
for 2h; Reflux;92%
Stage #1: 5-bromo-1H-indazole With ferrocene; tert-butylammonium hexafluorophosphate(V) In acetonitrile at 20℃; for 3h; Electrochemical reaction; Inert atmosphere; Glovebox;
Stage #2: acetic anhydride In acetonitrile for 2h; Electrochemical reaction; Inert atmosphere; Glovebox;
72%
With pyridine; dmap In dichloromethane at 40℃;70%
5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

benzyl bromide
100-39-0

benzyl bromide

A

2-benzyl-5-bromo-2H-indazole
937049-51-9

2-benzyl-5-bromo-2H-indazole

B

1-benzyl-5-bromo-1H-indazole
1087160-01-7

1-benzyl-5-bromo-1H-indazole

Conditions
ConditionsYield
Stage #1: 5-bromo-1H-indazole With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.166667h;
Stage #2: benzyl bromide In N,N-dimethyl-formamide at 0 - 20℃; for 2h;
A 88%
B 92%
With tetra-(n-butyl)ammonium iodide; sodium hydroxide In para-xylene at 130℃;A 302 mg
B 364 mg
5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

methyl iodide
74-88-4

methyl iodide

ClO4(1-)*C9H10BrN2(1+)

ClO4(1-)*C9H10BrN2(1+)

Conditions
ConditionsYield
Stage #1: 5-bromo-1H-indazole; methyl iodide With sodium hydroxide In methanol at 100℃; Sealed tube;
Stage #2: With perchloric acid In water at 20℃;
92%
5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

phenylmethanethiol
100-53-8

phenylmethanethiol

5-(benzylthio)-1H-indazole

5-(benzylthio)-1H-indazole

Conditions
ConditionsYield
With tris-(dibenzylideneacetone)dipalladium(0); N-ethyl-N,N-diisopropylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene In 1,4-dioxane at 90℃; for 4h; Inert atmosphere;92%
With tris-(dibenzylideneacetone)dipalladium(0); N-ethyl-N,N-diisopropylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene In 1,4-dioxane at 90℃; for 4h; Inert atmosphere;92%
3,4-dihydro-2H-pyran
110-87-2

3,4-dihydro-2H-pyran

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

5-bromo-2-(tetrahydro-2H-pyran-2-yl)-2H-indazole
1178903-21-3

5-bromo-2-(tetrahydro-2H-pyran-2-yl)-2H-indazole

Conditions
ConditionsYield
With pyridinium p-toluenesulfonate In dichloromethane for 5h; regioselective reaction;91.8%
5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

4-isoquinolineboronic acid
192182-56-2

4-isoquinolineboronic acid

C16H11N3
1610790-51-6

C16H11N3

Conditions
ConditionsYield
With tris-(dibenzylideneacetone)dipalladium(0); tripotassium phosphate "n" hydrate; XPhos In butan-1-ol at 100℃; for 18h; Inert atmosphere;91.1%
With palladium diacetate; sodium carbonate; triphenylphosphine In 1,2-dimethoxyethane; water Suzuki Coupling;
5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

5-bromo-3-chloro-1H-indazole
36760-19-7

5-bromo-3-chloro-1H-indazole

Conditions
ConditionsYield
With N-chloro-succinimide; 2,4,6-trimethylaniline In acetonitrile at 20℃; for 24h; Inert atmosphere;91%
With 1-chloro-1λ3-benzo[d][1,2]iodaoxol-3(1H)-one In N,N-dimethyl-formamide at 20℃; for 12h; regioselective reaction;86%
With N-chloro-succinimide In acetonitrile at 65℃; for 3h;48.7%
zinc(II) cyanide
557-21-1

zinc(II) cyanide

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

1H-indazole-5-carbonitrile
74626-47-4

1H-indazole-5-carbonitrile

Conditions
ConditionsYield
dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; bis(dibenzylideneacetone)-palladium(0) In water; N,N-dimethyl-formamide at 150℃; for 0.75h; Sealed vial;91%
With tris-(dibenzylideneacetone)dipalladium(0); 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene In water; N,N-dimethyl-formamide at 150℃; for 1.5h; Inert atmosphere; Microwave irradiation;24%
methanol
67-56-1

methanol

carbon monoxide
201230-82-2

carbon monoxide

5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

1H-indazole-5-carboxylic acid
61700-61-6

1H-indazole-5-carboxylic acid

Conditions
ConditionsYield
With 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; triethylamine; palladium dichloride In acetonitrile at 100℃; under 30003 Torr; for 18h;90%
5-bromo-1H-indazole
53857-57-1

5-bromo-1H-indazole

5-bromo-4-nitro-1H-indazole

5-bromo-4-nitro-1H-indazole

Conditions
ConditionsYield
With sulfuric acid; nitric acid In water at 0℃; for 1h;90%

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