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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price API 99% Ethacrynic acid 58-54-8 GMP Manufacturer

Cas:58-54-8

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality etacrynic acid

Cas:58-54-8

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Ethacrynic acid

Cas:58-54-8

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

Ethacrynic acid CAS 58-54-8

Cas:58-54-8

Min.Order:1 Kilogram

FOB Price: $70.0 / 90.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Acetic acid,2-[2,3-dichloro-4-(2-methylene-1-oxobutyl)phenoxy]- 58-54-8

Cas:58-54-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Etacrynic Acid/CAS:58-54-8

Cas:58-54-8

Min.Order:1 Gram

FOB Price: $454.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

Ethacrynic acid CAS:58-54-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediate

Ethacrynic acid CAS:58-54-8

Cas:58-54-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Acetic acid,2-[2,3-dichloro-4-(2-methylene-1-oxobutyl)phenoxy]-

Cas:58-54-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Superiority We can customize and synthesize products that other suppliers may not be able to provide. Advantage cof, mof ligand manufacturer Product Detail bes

99% Ethacrynic Acid CAS:58-54-8

Cas:58-54-8

Min.Order:100 Kilogram

Negotiable

Type:Trading Company

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

Ethacrynic acid

Cas:58-54-8

Min.Order:1 Kilogram

FOB Price: $40.0 / 50.0

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Acetic acid,2-[2,3-dichloro-4-(2-methylene-1-oxobutyl)phenoxy]-

Cas:58-54-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Ethacrynic acid CAS NO.58-54-8

Cas:58-54-8

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Ethacrynic acid

Cas:58-54-8

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hefei Zhaobo Technology Co., Ltd.

Ethacrynic acid cas 58-54-8 Purity: 99% Min Application: Intermediates Appearance: Powder Package: Bag Delivery: 3-5days Our Advantage & Service 1.Top quality: Using high quality material and establishing a strict quality control sys

Ethacrynic acid cas 58-54-8

Cas:58-54-8

Min.Order:1 Kilogram

FOB Price: $10.0 / 50.0

Type:Trading Company

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Hangzhou Fonlynn Health Technology Co., Ltd.

Packing: According to customer requirements Delivery time: In stock or depands Port of shipment: Ningbo/Shanghai/Qingdao OEM/ODM:Welcome Sample:We can offer our existing samples at once Transportation:Express/Sea/Air Port:Ningbo/Shanghai/Qingd

Ethacrynic acid

Cas:58-54-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Ethacrynic acid

Cas:58-54-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

Ethacrynic Acid

Cas:58-54-8

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

Ethacrynic acid CAS NO.58-54-8

Cas:58-54-8

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

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TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

Ethacrynic acid

Cas:58-54-8

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung, LG, Merck, Thermo Fisher Scientific and so o

58-54-8

Cas:58-54-8

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

Ethacrynic acid Manufacturer/High quality/Best price/In stock

Cas:58-54-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Buy Top Purity Ethacrynic acid

Cas:58-54-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

Ethacrynic acid CAS NO.58-54-8

Cas:58-54-8

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

Ethacrynic acid

Cas:58-54-8

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

Ethacrynic acid CAS NO.58-54-8

Cas:58-54-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

99% Ethacrynic Acid CAS:58-54-8 CAS NO.58-54-8

Cas:58-54-8

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

Ethacrynic acid

Cas:58-54-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:Active Pharmaceutical I

Ethacrynic acid

Cas:58-54-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

Ethacrynic acid

Cas:58-54-8

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

Ethacrynic acid CAS NO.58-54-8

Cas:58-54-8

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Synthetic route

formaldehyd
50-00-0

formaldehyd

<2,3-dichloro-4-(1-oxobutyl)phenyloxy>acetic acid
1217-67-0

<2,3-dichloro-4-(1-oxobutyl)phenyloxy>acetic acid

ethacrynic acid
58-54-8

ethacrynic acid

Conditions
ConditionsYield
With potassium carbonate In ethanol; water at 90℃; for 10h;80.5%
t-butylamine salt of ethacrynic acid

t-butylamine salt of ethacrynic acid

ethacrynic acid
58-54-8

ethacrynic acid

Conditions
ConditionsYield
With hydrogenchloride In water; ethyl acetate at 30℃; for 0.5h; pH=2 - 3;60.1%
2,3-dichloro-4-(2-methylenebutyryl)-phenol
4115-00-8

2,3-dichloro-4-(2-methylenebutyryl)-phenol

ethacrynic acid
58-54-8

ethacrynic acid

formaldehyd
50-00-0

formaldehyd

2,3-Dichlor-4-butyryl-phenoxyessigsaeure-aethylester
2977-51-7

2,3-Dichlor-4-butyryl-phenoxyessigsaeure-aethylester

ethacrynic acid
58-54-8

ethacrynic acid

Conditions
ConditionsYield
Stage #1: formaldehyd; 2,3-Dichlor-4-butyryl-phenoxyessigsaeure-aethylester With potassium carbonate Aldol condensation;
Stage #2: With hydrogenchloride; water
With potassium carbonate In ethanol; water for 24h; Aldol Condensation; Reflux;
2',3'-dichloro-4'-hydroxybutyrophenone
2350-46-1

2',3'-dichloro-4'-hydroxybutyrophenone

ethacrynic acid
58-54-8

ethacrynic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: potassium carbonate / toluene / 48 h / Reflux
2: potassium carbonate / ethanol; water / 24 h / Reflux
View Scheme
Multi-step reaction with 2 steps
1.1: potassium carbonate; potassium iodide / acetone / 0.5 h
1.2: 4 h / 60 °C
1.3: 2 h / 20 °C
2.1: potassium carbonate / ethanol; water / 10 h / 90 °C
View Scheme
Multi-step reaction with 4 steps
1.1: potassium carbonate / ethanol / 0.33 h / 30 °C
1.2: 12 h / 30 - 83 °C
2.1: N,N-dimethyl-formamide / 0.17 h / 30 °C
2.2: 12 h / 100 °C
3.1: N,N-dimethyl-formamide; toluene / 5 h / 20 - 30 °C
4.1: hydrogenchloride / ethyl acetate; water / 0.5 h / 30 °C / pH 2 - 3
View Scheme
2,3-dichlorophenol
576-24-9

2,3-dichlorophenol

ethacrynic acid
58-54-8

ethacrynic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: aluminum (III) chloride / carbon disulfide
2: potassium carbonate / toluene / 48 h / Reflux
3: potassium carbonate / ethanol; water / 24 h / Reflux
View Scheme
Multi-step reaction with 4 steps
1.1: potassium carbonate / acetone / 0.5 h
1.2: 3 h / 60 °C
2.1: aluminum (III) chloride / dichloromethane / 3.5 h / 0 - 40 °C
2.2: 3 h / 20 °C / Cooling with ice
3.1: potassium carbonate; potassium iodide / acetone / 0.5 h
3.2: 4 h / 60 °C
3.3: 2 h / 20 °C
4.1: potassium carbonate / ethanol; water / 10 h / 90 °C
View Scheme
Os(η6-p-cymene)(acetylacetonato)(2-(2,3-dichloro-4-(2-ethylenebutanoyl)phenoxy)acetato)

Os(η6-p-cymene)(acetylacetonato)(2-(2,3-dichloro-4-(2-ethylenebutanoyl)phenoxy)acetato)

A

[(η6-p-cymene)Os(acetylacetonato)Cl]

[(η6-p-cymene)Os(acetylacetonato)Cl]

B

ethacrynic acid
58-54-8

ethacrynic acid

Conditions
ConditionsYield
In water; dimethyl sulfoxide at 37℃; for 72h;
2,3-dichloroanisole
1984-59-4

2,3-dichloroanisole

ethacrynic acid
58-54-8

ethacrynic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: aluminum (III) chloride / dichloromethane / 3.5 h / 0 - 40 °C
1.2: 3 h / 20 °C / Cooling with ice
2.1: potassium carbonate; potassium iodide / acetone / 0.5 h
2.2: 4 h / 60 °C
2.3: 2 h / 20 °C
3.1: potassium carbonate / ethanol; water / 10 h / 90 °C
View Scheme
Multi-step reaction with 5 steps
1.1: aluminum (III) chloride / dichloromethane / 0.17 h / 30 °C
1.2: 8 h / 20 - 30 °C
1.3: 8 h / 30 - 42 °C
2.1: potassium carbonate / ethanol / 0.33 h / 30 °C
2.2: 12 h / 30 - 83 °C
3.1: N,N-dimethyl-formamide / 0.17 h / 30 °C
3.2: 12 h / 100 °C
4.1: N,N-dimethyl-formamide; toluene / 5 h / 20 - 30 °C
5.1: hydrogenchloride / ethyl acetate; water / 0.5 h / 30 °C / pH 2 - 3
View Scheme
C26H22Cl12Nb2O8

C26H22Cl12Nb2O8

ethacrynic acid
58-54-8

ethacrynic acid

Conditions
ConditionsYield
In diethyl ether; water at 20℃; for 48h; Inert atmosphere;
<2,3-dichloro-4-(1-oxobutyl)phenyloxy>acetic acid
1217-67-0

<2,3-dichloro-4-(1-oxobutyl)phenyloxy>acetic acid

ethacrynic acid
58-54-8

ethacrynic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: N,N-dimethyl-formamide / 0.17 h / 30 °C
1.2: 12 h / 100 °C
2.1: N,N-dimethyl-formamide; toluene / 5 h / 20 - 30 °C
3.1: hydrogenchloride / ethyl acetate; water / 0.5 h / 30 °C / pH 2 - 3
View Scheme
(2,3-dichloro-4-[2-dimethylaminomethyl-butyryl]phenoxy)acetic acid
1160-10-7

(2,3-dichloro-4-[2-dimethylaminomethyl-butyryl]phenoxy)acetic acid

ethacrynic acid
58-54-8

ethacrynic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: N,N-dimethyl-formamide; toluene / 5 h / 20 - 30 °C
2: hydrogenchloride / ethyl acetate; water / 0.5 h / 30 °C / pH 2 - 3
View Scheme
ethacraplatin
847227-34-3

ethacraplatin

B

ethacrynic acid
58-54-8

ethacrynic acid

Conditions
ConditionsYield
With sodium L-ascorbate In tetrahydrofuran; aq. phosphate buffer; dimethyl sulfoxide at 20℃; pH=7.4; Kinetics;
C13H18Cl4N2O5Pt

C13H18Cl4N2O5Pt

B

ethacrynic acid
58-54-8

ethacrynic acid

Conditions
ConditionsYield
With sodium L-ascorbate In aq. phosphate buffer at 20℃; pH=7.4; Kinetics;
ethacrynic acid
58-54-8

ethacrynic acid

2-(2,3-dichloro-4-(2-methylbutanoyl)phenoxy)acetic acid
5378-94-9

2-(2,3-dichloro-4-(2-methylbutanoyl)phenoxy)acetic acid

Conditions
ConditionsYield
With hydrogen; palladium In methanol at 20℃; for 12h;100%
With palladium on activated charcoal; hydrogen In isopropyl alcohol under 2250.23 Torr; for 0.333333h; Inert atmosphere;100%
With L-Selectride In tetrahydrofuran at -78℃; for 2h; Inert atmosphere;56%
ethacrynic acid
58-54-8

ethacrynic acid

<2,3-dichloro-4-(2-methylenebutyryl)phenoxy>acetyl chloride
113239-57-9

<2,3-dichloro-4-(2-methylenebutyryl)phenoxy>acetyl chloride

Conditions
ConditionsYield
With oxalyl dichloride at 70℃; for 1h;98.13%
With thionyl chloride In benzene for 1.25h; Heating;
With oxalyl dichloride In toluene Heating;
ethacrynic acid
58-54-8

ethacrynic acid

methyl (E)-3-aminocrotonate
14205-39-1

methyl (E)-3-aminocrotonate

<2,3-Dichlor-4-(3-ethyl-5-methoxycarbonyl-6-methyl-pyridin-2-yl)phenoxy>-essigsaeure
104684-27-7

<2,3-Dichlor-4-(3-ethyl-5-methoxycarbonyl-6-methyl-pyridin-2-yl)phenoxy>-essigsaeure

Conditions
ConditionsYield
at 120℃; for 0.5h;98%
ethacrynic acid
58-54-8

ethacrynic acid

diethyl malonate
105-53-3

diethyl malonate

2-[2-(4-Carboxymethoxy-2,3-dichloro-benzoyl)-butyl]-malonic acid diethyl ester
183430-20-8

2-[2-(4-Carboxymethoxy-2,3-dichloro-benzoyl)-butyl]-malonic acid diethyl ester

Conditions
ConditionsYield
With sodium ethanolate In ethanol for 0.0833333h; Ambient temperature;98%
ethacrynic acid
58-54-8

ethacrynic acid

ethyl acetoacetate
141-97-9

ethyl acetoacetate

2-Acetyl-4-(4-carboxymethoxy-2,3-dichloro-benzoyl)-hexanoic acid ethyl ester

2-Acetyl-4-(4-carboxymethoxy-2,3-dichloro-benzoyl)-hexanoic acid ethyl ester

Conditions
ConditionsYield
With sodium ethanolate In ethanol for 0.25h; Ambient temperature;93%
ethacrynic acid
58-54-8

ethacrynic acid

tert-butyl N-(6-aminohexyl)carbamate
51857-17-1

tert-butyl N-(6-aminohexyl)carbamate

C24H34Cl2N2O5

C24H34Cl2N2O5

Conditions
ConditionsYield
With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃;93%
p-hydroxyphenethyl alcohol
501-94-0

p-hydroxyphenethyl alcohol

ethacrynic acid
58-54-8

ethacrynic acid

4-hydroxyphenethyl 2-(2,3-dichloro-4-(2-methylenebutanoyl)phenoxy)acetate

4-hydroxyphenethyl 2-(2,3-dichloro-4-(2-methylenebutanoyl)phenoxy)acetate

Conditions
ConditionsYield
With toluene-4-sulfonic acid In dichloromethane for 12h; Inert atmosphere;92%
With toluene-4-sulfonic acid In dichloromethane at 0 - 50℃; for 12h;92%
ethacrynic acid
58-54-8

ethacrynic acid

1-Adamantanamine
768-94-5

1-Adamantanamine

C23H27Cl2NO3

C23H27Cl2NO3

Conditions
ConditionsYield
With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃;92%
ethacrynic acid
58-54-8

ethacrynic acid

[2,3-Dichloro-4-(4-ethyl-4,5-dihydro-1H-pyrazol-3-yl)-phenoxy]-acetic acid

[2,3-Dichloro-4-(4-ethyl-4,5-dihydro-1H-pyrazol-3-yl)-phenoxy]-acetic acid

Conditions
ConditionsYield
With hydrazine hydrate; N-ethyl-N,N-diisopropylamine In methanol at 60℃; for 12h;89%
ethacrynic acid
58-54-8

ethacrynic acid

4-(hydroxymethyl)-4'-methyl-2,2'-bipyridine
81998-04-1

4-(hydroxymethyl)-4'-methyl-2,2'-bipyridine

(4′-methyl-[2,2′-bipyridin]-4-yl)methyl-2-(2,3-dichloro-4-(2-methylenebutanoyl)phenoxy)acetate

(4′-methyl-[2,2′-bipyridin]-4-yl)methyl-2-(2,3-dichloro-4-(2-methylenebutanoyl)phenoxy)acetate

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 24h; Schlenk technique; Inert atmosphere;88%
ethacrynic acid
58-54-8

ethacrynic acid

4-azidobutan-1-amine
88192-20-5

4-azidobutan-1-amine

1-{4-[(4-azidobutylaminooxy)methyl]-2,3-dichlorophenyl}-2-methylenebutan-1-one
1284258-80-5

1-{4-[(4-azidobutylaminooxy)methyl]-2,3-dichlorophenyl}-2-methylenebutan-1-one

Conditions
ConditionsYield
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide for 1h; Inert atmosphere;86%
ethacrynic acid
58-54-8

ethacrynic acid

(o-hydroxyphenyl)diphenylphosphine
60254-10-6

(o-hydroxyphenyl)diphenylphosphine

C31H25Cl2O4P

C31H25Cl2O4P

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 24h; Inert atmosphere; Schlenk technique;86%
nitromethane
75-52-5

nitromethane

ethacrynic acid
58-54-8

ethacrynic acid

<2,3-Dichlor-4-(2-ethyl-4-nitrobutyryl)phenoxy>essigsaeure
138470-10-7

<2,3-Dichlor-4-(2-ethyl-4-nitrobutyryl)phenoxy>essigsaeure

Conditions
ConditionsYield
With sodium methylate In methanol for 0.0833333h; Ambient temperature;83%
other nitroalkanes;
ethacrynic acid
58-54-8

ethacrynic acid

N-(4-aminobutyl)carbaminsaeure-(tert-butyl)ester-hydrochlorid
33545-98-1

N-(4-aminobutyl)carbaminsaeure-(tert-butyl)ester-hydrochlorid

C22H30Cl2N2O5

C22H30Cl2N2O5

Conditions
ConditionsYield
With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃;83%
ethacrynic acid
58-54-8

ethacrynic acid

6-amino-9-(4-(aminomethyl)benzyl)-2-(2-methoxyethoxy)-9H-purin-8-ol

6-amino-9-(4-(aminomethyl)benzyl)-2-(2-methoxyethoxy)-9H-purin-8-ol

C29H30Cl2N6O6

C29H30Cl2N6O6

Conditions
ConditionsYield
With dmap; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine In N,N-dimethyl acetamide at 20℃; for 10h; Concentration; Solvent; Time;80.7%
ethacrynic acid
58-54-8

ethacrynic acid

4-diphenylphosphanobenzoic acid
2129-31-9

4-diphenylphosphanobenzoic acid

2-((4-(diphenylphosphanyl)benzyl)oxy)ethyl-2-(2,3-dichloro-4-(2-methylenebutanoyl)phenoxy) acetate

2-((4-(diphenylphosphanyl)benzyl)oxy)ethyl-2-(2,3-dichloro-4-(2-methylenebutanoyl)phenoxy) acetate

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 6.5h; Inert atmosphere; Schlenk technique;79%
pyridine-4-methanol
586-95-8

pyridine-4-methanol

ethacrynic acid
58-54-8

ethacrynic acid

pyridin-4-yl-methyl 2-(2,3-dichloro-4-(2-methylenebutanoyl)phenoxy)acetate

pyridin-4-yl-methyl 2-(2,3-dichloro-4-(2-methylenebutanoyl)phenoxy)acetate

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; Inert atmosphere;77%
ethacrynic acid
58-54-8

ethacrynic acid

sodium cyanide
143-33-9

sodium cyanide

<2,3-Dichlor-4-(2-cyanmethylbutyryl)phenoxy>essigsaeure
138470-12-9

<2,3-Dichlor-4-(2-cyanmethylbutyryl)phenoxy>essigsaeure

Conditions
ConditionsYield
In ethanol for 12h; Ambient temperature;76%
ethacrynic acid
58-54-8

ethacrynic acid

ethylene glycol
107-21-1

ethylene glycol

2-hydroxyethyl-2-(2,3-dichloro-4-(2-methylenebutanoyl)phenoxy)acetate

2-hydroxyethyl-2-(2,3-dichloro-4-(2-methylenebutanoyl)phenoxy)acetate

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 24h; Schlenk technique; Inert atmosphere;76%
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; Inert atmosphere;75%
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride at 20℃; for 2.5h;64%
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride at 20℃; for 15h; Schlenk technique;26%
(S)-Ethyl lactate
687-47-8

(S)-Ethyl lactate

ethacrynic acid
58-54-8

ethacrynic acid

(S)-2-(2,3-Dichlor-4-(2-methylen-1-oxobutyl)-phenoxyacetyl)-oxypropionsaeureethylester

(S)-2-(2,3-Dichlor-4-(2-methylen-1-oxobutyl)-phenoxyacetyl)-oxypropionsaeureethylester

Conditions
ConditionsYield
With dicyclohexyl-carbodiimide; dmap In dichloromethane -10 to -5 deg C, 30 min then room temp.;75.7%
(η6-p-cymene)bis(acetylacetonato)osmium

(η6-p-cymene)bis(acetylacetonato)osmium

ethacrynic acid
58-54-8

ethacrynic acid

Os(η6-p-cymene)(acetylacetonato)(2-(2,3-dichloro-4-(2-ethylenebutanoyl)phenoxy)acetato)

Os(η6-p-cymene)(acetylacetonato)(2-(2,3-dichloro-4-(2-ethylenebutanoyl)phenoxy)acetato)

Conditions
ConditionsYield
In dichloromethane at 20℃; for 24h;75%
ethacrynic acid
58-54-8

ethacrynic acid

N-BOC-1,2-diaminoethane
57260-73-8

N-BOC-1,2-diaminoethane

C20H26Cl2N2O5

C20H26Cl2N2O5

Conditions
ConditionsYield
With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃;73%
ethacrynic acid
58-54-8

ethacrynic acid

ethyl acetoacetate
141-97-9

ethyl acetoacetate

[2,3-dichloro-4-(6ethyl-3-oxo-1-cyclohexen-1-yl)phenoxy]acetic acid
183430-18-4

[2,3-dichloro-4-(6ethyl-3-oxo-1-cyclohexen-1-yl)phenoxy]acetic acid

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In ethanol for 3h; Heating;72%
With sodium methylate In ethanol; water
ethacrynic acid
58-54-8

ethacrynic acid

niobium pentachloride
10026-12-7

niobium pentachloride

C26H22Cl12Nb2O8

C26H22Cl12Nb2O8

Conditions
ConditionsYield
In dichloromethane at 20℃; for 4h; Schlenk technique; Inert atmosphere;72%
ethacrynic acid
58-54-8

ethacrynic acid

2-[2-(adamantan-1-yloxy)-ethoxy]-ethanol
1266678-98-1

2-[2-(adamantan-1-yloxy)-ethoxy]-ethanol

C27H34Cl2O6

C27H34Cl2O6

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃;72%
Nitroethane
79-24-3

Nitroethane

ethacrynic acid
58-54-8

ethacrynic acid

<2,3-Dichlor-4-(2-ethyl-4-nitrovaleryl)phenoxy>essigsaeure
138470-11-8

<2,3-Dichlor-4-(2-ethyl-4-nitrovaleryl)phenoxy>essigsaeure

Conditions
ConditionsYield
With sodium methylate In methanol for 4h; Heating;71%

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