Cas no. 585-50-2 3-(3-Trifluoromethylphenyl)propionic acid API or Intermediates Our products are high quality, good price, quick delivery time and we supply all customers best service in the long-term cooperation as below: 1.Established manufactu
Cas:585-50-2
Min.Order:100 Gram
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inquiryDayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe
Cas:585-50-2
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inquiry3-(3-Trifluoromethylphenyl)propionic acid CAS No.:585-50-2 Name: 3-(3-Trifluoromethylphenyl)propionic acid Molecular Structure Molecular
Cas:585-50-2
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inquiryhigh quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai
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inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
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inquiryChengdu words and import and export co., LTD is one specialized is engaged in pharmaceutical intermediates, fine chemical industry in the field of research. Development and production of high-tech enterprises.We can provide Ephedrine products to ne
Cas:585-50-2
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inquiryProduct Description Product website: http://www.finerchem.com/pro01en/id/1172.html Product Name 3-(3-Trifluoromethylphenyl)propionic acid CAS No.
Cas:585-50-2
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inquiryTIANFUCHEM--585-50-2--3-(3-Trifluoromethylphenyl)propionic acid factory price Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had established
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inquiryLIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc.
Cas:585-50-2
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inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
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inquiry3-(3-Trifluoromethylphenyl)propionic acid Product name 3-(3-Trifluoromethylphenyl)propionic acid Synonyms Hydrocinnamicacid, m-(trifluoromethyl)- (7CI,8CI) CAS No. 585-50
Cas:585-50-2
Min.Order:1 Kilogram
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inquiryOur Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con
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inquiry1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:powder Storage:Store in sealed containers at cool & dry pla
Cas:585-50-2
Min.Order:100 Gram
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inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:585-50-2
Min.Order:1 Kilogram
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inquiryBeluga chemical professional supply 3-(3-Trifluoromethylphenyl)propionic acid CAS 585-50-2 1. Beluga Chemical has a professional RESEARCH and development team and strong technical force to ensure technical support and research capabilities. 2. Ma
Cas:585-50-2
Min.Order:1 Gram
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Type:Lab/Research institutions
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Min.Order:1 Kilogram
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inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Product Name: 3-(3-Trifluoromethylphenyl)propionic acid Synonyms: RARECHEM AL BO 1070;3-(3'-TRIFLUOROMETHYLPHENYL)-PROPIONIC ACID;3-Trifluoromethylbenzenepropanoic acid;3-(3-Trifluoromethylphenyl)propionic acid ,97%;3-(3-TRIFLUOROMETHYLPHENY
Cas:585-50-2
Min.Order:100 Gram
Negotiable
Type:Lab/Research institutions
inquiryAppearance: White or off-white Solid Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:Common products:S
Cas:585-50-2
Min.Order:100 Metric Ton
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inquiryHangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
Cas:585-50-2
Min.Order:0 Metric Ton
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inquiryCompany Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments
Cas:585-50-2
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
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Min.Order:0
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inquiryWhy Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu
Cas:585-50-2
Min.Order:1 Gram
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Type:Other
inquiryOur Advantages Production: Advanced chemical equipment with years of experience.Staffs for producing various extract products. Quality Control:A complete set of Testing Professional and Analysis Equipment ensures the Quality Requirements and Speci
Cas:585-50-2
Min.Order:1 Kilogram
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Type:Trading Company
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:585-50-2
Min.Order:10 Gram
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inquiryProduct name: 3-(3-Trifluoromethylphenyl)Propionic Acid CAS No.:585-50-2 Molecule Formula:C10H9F3O2 Molecule Weight:218.17 Purity: 99.0% Package: 200kg/drum Description:Yellow liquid Manufacture Standards:Enterprise Standard TEST
Cas:585-50-2
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryProduct Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,
Cas:585-50-2
Min.Order:1 Metric Ton
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inquiry3-(3-Trifluoromethylphenyl)propionic acid Chemical Properties Melting point 35°C(lit.) Boiling point 149°C/11mmHg(lit.) density 1.307±0.06 g/cm3(Predicted) storage temp. Sealed in dry,Room Temperature pka 4.56±
Cas:585-50-2
Min.Order:1 Gram
FOB Price: $66.0
Type:Lab/Research institutions
inquiryfactory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
Cas:585-50-2
Min.Order:1 Kilogram
FOB Price: $18.0 / 20.0
Type:Trading Company
inquiryZhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed
Cas:585-50-2
Min.Order:1 Kilogram
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inquiryConditions | Yield |
---|---|
With hydrogen; palladium dihydroxide at 40 - 60℃; under 2250.23 Torr; | 100% |
With palladium on activated charcoal; hydrogen; sodium carbonate In water at 25℃; under 1500.15 - 2250.23 Torr; for 3h; | 99.4% |
With hydrogen; palladium on activated charcoal In methanol at 20 - 25℃; under 30.003 Torr; | 95.2% |
Conditions | Yield |
---|---|
With hydrogen; 5% Pd(II)/C(eggshell) In methanol at 25℃; under 735.572 Torr; for 10h; | 100% |
Stage #1: 3-(trifluoromethyl)cinnamic acid With palladium diacetate; 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane In dichloromethane at 25℃; for 12h; Schlenk technique; Inert atmosphere; Stage #2: With hydrogenchloride In water | 97% |
With palladium diacetate; 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane In dichloromethane at 25℃; for 12h; Sealed tube; Inert atmosphere; chemoselective reaction; | 97% |
3-(3-(trifluoromethyl)phenyl)propanenitrile
3-(3-trifluoromethylphenyl)propanoic acid
Conditions | Yield |
---|---|
With hydrogenchloride; water for 4.5h; Product distribution / selectivity; | 94% |
With sodium hydroxide; water In ethylene glycol at 125℃; for 9h; Product distribution / selectivity; |
2-vinyl-1,3-dioxolane
3-bromo-1-trifluoromethylbenzene
3-(3-trifluoromethylphenyl)propanoic acid
Conditions | Yield |
---|---|
Stage #1: 2-vinyl-1,3-dioxolane; 3-bromo-1-trifluoromethylbenzene With potassium carbonate; Pd-Tedicyp catalyst In N,N-dimethyl-formamide at 110℃; for 20h; Heck reaction; Stage #2: With sodium hydroxide; water In N,N-dimethyl-formamide at 50 - 80℃; | 93% |
A
3-(3-trifluoromethylphenyl)propanoic acid
B
(E)-3-(3-(trifluoromethyl)phenyl)acrylaldehyde
Conditions | Yield |
---|---|
With edetate disodium; thiamine diphosphate; sodium citrate; magnesium chloride In water; acetonitrile at 20℃; Rate constant; pH 6.0, brewers' yeast pyruvate decarboxylase (PDC, EC 4.1.1.1), also in the presence of pyruvamide; |
3-(3-trifluoromethylphenyl)propanoic acid
Conditions | Yield |
---|---|
With carbon dioxide; magnesium |
3-(3-trifluoromethylphenyl)propanoic acid
Conditions | Yield |
---|---|
Stage #1: m-trifluoromethyl-α-chlorohydrocinnamic acid With acetic acid; zinc In water at 20 - 35℃; for 1h; Stage #2: With hydrogenchloride In water at 20℃; Product distribution / selectivity; |
methyl 3-(3-(trifluoromethyl)phenyl)propanoate
3-(3-trifluoromethylphenyl)propanoic acid
Conditions | Yield |
---|---|
Stage #1: methyl 3-(3-(trifluoromethyl)phenyl)propanoate With sodium hydroxide; isopropyl alcohol at 20℃; for 6h; Stage #2: With hydrogenchloride; water | |
Stage #1: methyl 3-(3-(trifluoromethyl)phenyl)propanoate With lithium hydroxide monohydrate In tetrahydrofuran; water at 20℃; for 48h; Stage #2: With hydrogenchloride In tetrahydrofuran; diethyl ether; water | |
With water; sodium hydroxide In methanol at 20℃; for 4h; | 3.9 g |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: piperidine / pyridine / 50 - 75 °C / Inert atmosphere 1.2: 0 °C / Cooling with ice 2.1: hydrogen / palladium 10% on activated carbon / methanol / 2.5 h / 750.08 Torr View Scheme | |
Multi-step reaction with 2 steps 1.1: pyridine; piperidine / 4.25 h / 20 - 120 °C / Inert atmosphere 1.2: pH 2 2.1: sodium hydroxide / water / 20 °C 2.2: 7 h / 25 - 30 °C / 750.08 Torr 2.3: pH 2 View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: palladium diacetate; potassium carbonate; triphenylphosphine / N,N-dimethyl-formamide / 15 h / 110 °C / Inert atmosphere 1.2: 15 h / 20 °C / 760.05 Torr 2.1: lithium hydroxide monohydrate / tetrahydrofuran; water / 48 h / 20 °C View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: sodium hydride / tetrahydrofuran / 0.5 h / 0 - 5 °C 1.2: 2 h 2.1: sodium chloride / water; N,N-dimethyl-formamide / 6 h / 150 °C 3.1: sodium hydroxide; water / methanol / 4 h / 20 °C View Scheme |
3-(3-trifluoromethylphenyl)propanoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: sodium chloride / water; N,N-dimethyl-formamide / 6 h / 150 °C 2: sodium hydroxide; water / methanol / 4 h / 20 °C View Scheme |
methanol
3-(3-trifluoromethylphenyl)propanoic acid
methyl 3-(3-(trifluoromethyl)phenyl)propanoate
Conditions | Yield |
---|---|
With sulfuric acid Reflux; | 99% |
With thionyl chloride for 4h; Inert atmosphere; Reflux; | 97% |
With sulfuric acid at 30 - 45℃; |
3-(3-trifluoromethylphenyl)propanoic acid
C22H17F3N2OS
Conditions | Yield |
---|---|
With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; triethylamine In chloroform at 120℃; Microwave irradiation; | 98% |
3-(3-trifluoromethylphenyl)propanoic acid
(R)-<1-(1-Naphthyl)ethyl>ammonium chloride
(R)‐N‐(1‐(naphthalen‐1‐yl)ethyl)‐3‐(3‐trifluoromethylphenyl)propanamide
Conditions | Yield |
---|---|
Stage #1: (R)-<1-(1-Naphthyl)ethyl>ammonium chloride With sodium hydroxide In toluene Stage #2: 3-(3-trifluoromethylphenyl)propanoic acid In toluene at 140 - 150℃; Further stages.; | 95% |
3-(3-trifluoromethylphenyl)propanoic acid
3-[3-(trifluoromethyl)phenyl]propan-1-ol
Conditions | Yield |
---|---|
Stage #1: 3-(3-trifluoromethylphenyl)propanoic acid With borane-THF In tetrahydrofuran at 0 - 20℃; for 25h; Stage #2: With water In tetrahydrofuran; methanol | 94% |
With borane In tetrahydrofuran at 0 - 20℃; for 25h; Inert atmosphere; | 94% |
Stage #1: 3-(3-trifluoromethylphenyl)propanoic acid With 4-methyl-morpholine; chloroformic acid ethyl ester In 2-methyltetrahydrofuran at -10 - -5℃; for 0.00166667h; Stage #2: With sodium tetrahydroborate In 2-methyltetrahydrofuran; water at 0 - 5℃; for 0.5h; Solvent; Reagent/catalyst; | 92.2% |
3-(3-trifluoromethylphenyl)propanoic acid
3-(trifluoromethyl)benzenepropanoic acid chloride
Conditions | Yield |
---|---|
With thionyl chloride; N,N-dimethyl-formamide In Isopropyl acetate at 43℃; Temperature; | 93% |
With thionyl chloride | |
With thionyl chloride In toluene for 2h; Heating; |
(R)-1-(1-Naphthyl)ethylamine
3-(3-trifluoromethylphenyl)propanoic acid
cinacalcet
Conditions | Yield |
---|---|
With tris(pentafluorophenyl)borate; phenylsilane In dibutyl ether at 120℃; for 24h; Solvent; Reagent/catalyst; Concentration; Inert atmosphere; Schlenk technique; | 89% |
With tris(pentafluorophenyl)borate; phenylsilane In dibutyl ether at 120℃; for 20h; Schlenk technique; Inert atmosphere; | 87% |
With potassium phosphate; 18-crown-6 ether; phenylsilane In tetrahydrofuran at 80℃; for 36h; Glovebox; Molecular sieve; Schlenk technique; |
3-(3-trifluoromethylphenyl)propanoic acid
Conditions | Yield |
---|---|
With dmap; 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; triethylamine In N,N-dimethyl-formamide at 20℃; for 16h; | 86% |
(R)-1-(1-Naphthyl)ethylamine
3-(3-trifluoromethylphenyl)propanoic acid
(R)‐N‐(1‐(naphthalen‐1‐yl)ethyl)‐3‐(3‐trifluoromethylphenyl)propanamide
Conditions | Yield |
---|---|
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 15h; Inert atmosphere; | 83% |
Stage #1: 3-(3-trifluoromethylphenyl)propanoic acid With 1,1'-carbonyldiimidazole In dichloromethane for 1h; Stage #2: (R)-1-(1-Naphthyl)ethylamine In dichloromethane at 25 - 35℃; Solvent; Temperature; | 82.94% |
Stage #1: 3-(3-trifluoromethylphenyl)propanoic acid With thionyl chloride; N,N-dimethyl-formamide In toluene at 25 - 75℃; for 2h; Stage #2: (R)-1-(1-Naphthyl)ethylamine With triethylamine In dichloromethane; toluene at 0 - 5℃; for 1.5 - 2h; | 70.87% |
Conditions | Yield |
---|---|
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 12h; | 79% |
3-(3-trifluoromethylphenyl)propanoic acid
3-[3-(trifluoromethyl)phenyl]propanal
Conditions | Yield |
---|---|
With succinic acid anhydride; 4,4'-dibromo-2,2'-bipyridine; diphenylsilane; nickel(II) hydroxide In tetrahydrofuran at 70℃; for 10h; Schlenk technique; Inert atmosphere; | 75% |
Multi-step reaction with 2 steps 1: 85 percent / LAH 2: 65 percent / (COCl)2/DMSO; Et3N View Scheme | |
Multi-step reaction with 2 steps 1.1: sulfuric acid / 30 - 45 °C 2.1: diisobutylaluminium hydride / toluene; hexane / 2.5 h / -80 - -78 °C 2.2: -80 - -78 °C View Scheme | |
Multi-step reaction with 2 steps 1: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C / Inert atmosphere; Schlenk technique 2: Dess-Martin periodane / tetrahydrofuran / 2 h / 20 °C / Inert atmosphere; Schlenk technique View Scheme | |
Multi-step reaction with 2 steps 1: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C / Inert atmosphere 2: Dess-Martin periodane / dichloromethane / 0 - 20 °C / Inert atmosphere View Scheme |
(R)-1-(1-Naphthyl)ethylamine
3-(3-trifluoromethylphenyl)propanoic acid
cinacalcet hydrochloride
Conditions | Yield |
---|---|
Stage #1: (R)-1-(1-Naphthyl)ethylamine; 3-(3-trifluoromethylphenyl)propanoic acid With platinum(0)-1,3-divinyl-1,1,3,3-tetramethyldisiloxane complex; phenylsilane; 1,2-bis-(diphenylphosphino)ethane In dibutyl ether at 120℃; for 18h; Schlenk technique; Inert atmosphere; Stage #2: With hydrogenchloride In diethyl ether at -20℃; Schlenk technique; Inert atmosphere; | 74% |
Conditions | Yield |
---|---|
With aluminium(III) triflate; Co(acac)3; hydrogen; [2-((diphenylphospino)methyl)-2-methyl-1,3-propanediyl]bis[diphenylphosphine] at 140℃; under 22502.3 Torr; for 18h; Autoclave; Sealed tube; | 72% |
Conditions | Yield |
---|---|
With cobalt(II) tetrafluoroborate hexahydrate; (p-anisyl)triphos; hydrogen In 1,4-dioxane at 140℃; under 30003 Torr; for 24h; Autoclave; Green chemistry; | 69% |
Conditions | Yield |
---|---|
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane for 18h; Inert atmosphere; | 53% |
Stage #1: 3-(3-trifluoromethylphenyl)propanoic acid With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In tetrahydrofuran for 0.5h; Inert atmosphere; Stage #2: Succinimide In tetrahydrofuran for 48h; | 44% |
3-(3-trifluoromethylphenyl)propanoic acid
Conditions | Yield |
---|---|
With HATU In pyridine at 85℃; for 8h; Inert atmosphere; | 39% |
2-amino-1-(1-phenyl-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)ethanone
3-(3-trifluoromethylphenyl)propanoic acid
N-(2-oxo-2-(1-phenyl-3,4-dihydropyrrolo[1,2-a]pyrazin-2-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propanamide
Conditions | Yield |
---|---|
Stage #1: 3-(3-trifluoromethylphenyl)propanoic acid With 1,1'-carbonyldiimidazole In dichloromethane at 20℃; for 1h; Stage #2: 2-amino-1-(1-phenyl-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)ethanone In dichloromethane at 20℃; for 16h; | 38% |
3-(3-trifluoromethylphenyl)propanoic acid
3-[3-(trifluoromethyl)cyclohexyl]propanoic acid
Conditions | Yield |
---|---|
With acetic acid; platinum Hydrogenation; |
3-(3-trifluoromethylphenyl)propanoic acid
diazomethyl-trimethyl-silane
methyl 3-(3-(trifluoromethyl)phenyl)propanoate
Conditions | Yield |
---|---|
With methanol Esterification; |
4-{2-[(1S)-((S)-tert-butanesulfinylamino)-3-methylbutyl]-4-(trifluoromethyl)phenyl}-1-piperazine
3-(3-trifluoromethylphenyl)propanoic acid
Conditions | Yield |
---|---|
With N-(3-dimethylaminopropyl)-N-ethylcarbodiimide In dichloromethane; N,N-dimethyl-formamide |
3-(3-trifluoromethylphenyl)propanoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 85 percent / LAH 2: 65 percent / (COCl)2/DMSO; Et3N View Scheme |
3-(3-trifluoromethylphenyl)propanoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 85 percent / LAH 2: 65 percent / (COCl)2/DMSO; Et3N View Scheme |
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