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Yangzhou Qinyuan Pharmatech Co.,Ltd

Cas no. 779-89-5 3-[3-(Trifluoromethyl)phenyl]prop-2-enoic acid API or Intermediates Our products are high quality, good price, quick delivery time and we supply all customers best service in the long-term cooperation as below: 1.Established manu

3-[3-(Trifluoromethyl)phenyl]prop-2-enoic acid

Cas:779-89-5

Min.Order:100 Gram

Negotiable

Type:Trading Company

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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

3-(Trifluoromethyl)cinnamic acid

Cas:779-89-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 3-(Trifluoromethyl)Cinnamic Acid supplier in China

Cas:779-89-5

Min.Order:1 Metric Ton

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Type:Manufacturers

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Hangzhou Think Chemical Co. Ltd

3-(Trifluoromethyl)cinnamic acid CAS No.:779-89-5 Name: 3-(Trifluoromethyl)cinnamic acid

High purity 3-(Trifluoromethyl)cinnamic acid CAS No.:779-89-5

Cas:779-89-5

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Other

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Henan Allgreen Chemical Co.,Ltd

he company has advanced technology, as well as a large number of excellent R & D team, to provide customers from the grams to one hundred kilograms and tons of high-quality products, competitive prices and quality se T rvice Appearance:Whit

3-(TrifluoroMethyl)cinnaMic Acid

Cas:779-89-5

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermedi

3-(Trifluoromethyl)cinnamic acid

Cas:779-89-5

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 3-(trifluoromethyl)cinnamic acid

Cas:779-89-5

Min.Order:1

Negotiable

Type:Other

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

3-(Trifluoromethyl)Cinnamic Acid

Cas:779-89-5

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Chemwill Asia Co., Ltd.

3-(Trifluoromethyl)cinnamic acid CAS 779-89-5 In stock

Cas:779-89-5

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Manufacturers

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Jinan Finer Chemical Co., Ltd

Product Description Product website: http://www.finerchem.com/pro01en/id/1175.html Product Name 3-(Trifluoromethyl)cinnamic acid CAS No. 779

3-(Trifluoromethyl)cinnamic acid

Cas:779-89-5

Min.Order:1 Gram

FOB Price: $11.0

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

TIANFUCHEM--779-89-5--3-(Trifluoromethyl)cinnamic acid factory price Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had established stable bu

TIANFUCHEM--779-89-5--3-(Trifluoromethyl)cinnamic acid factory price

Cas:779-89-5

Min.Order:1 Metric Ton

FOB Price: $2000.0

Type:Lab/Research institutions

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LIDE PHARMACEUTICALS LIMITED

LIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc.

3-(Trifluoromethyl)cinnamic acid

Cas:779-89-5

Min.Order:1 Kilogram

FOB Price: $0.9 / 1.0

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

3-(Trifluoromethyl)cinnamic acid

Cas:779-89-5

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

ManufacturerCAS 779-89-5 with high quality products

Cas:779-89-5

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

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Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developmen

3-(Trifluoromethyl)cinnamic acid CAS NO.779-89-5

Cas:779-89-5

Min.Order:1 Kilogram

FOB Price: $2.0 / 6.0

Type:Trading Company

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Hubei Langyou International Trading Co., Ltd

Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is

3-(Trifluoromethyl)cinnamic acid CAS NO 779-89-5

Cas:779-89-5

Min.Order:1 Kilogram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2-Propenoic acid, 3-(3-(trifluoromethyl)phenyl)- 779-89-5

Cas:779-89-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

3-(Trifluoromethyl)cinnamic acid

Cas:779-89-5

Min.Order:1 Kilogram

FOB Price: $85.0 / 98.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

3-(Trifluoromethyl)cinnamic acid CAS:779-89-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality or

3-(Trifluoromethyl)cinnamic acid CAS:779-89-5

Cas:779-89-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2-Propenoic acid, 3-(3-(trifluoromethyl)phenyl)-

Cas:779-89-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Leader Biochemical Group

PRODUCT DETAILS

China Biggest Factory Manufacturer Supply 3-(Trifluoromethyl)cinnamic acid CAS 779-89-5

Cas:779-89-5

Min.Order:1 Kilogram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:779-89-5

Cas:779-89-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Wuhan Zenuo Biological Medicine Technology Co Ltd

Product Name: 3-(Trifluoromethyl)cinnamic acid Synonyms:(2E)-3-[3-(trifluoroMethyl)phenyl]prop-2-enoic acid; (E)-3-[3-(Trifluoromethyl)phenyl]prop-2-enoic acid;2-Propenoic acid, 3-[3-(trifluoromethyl)phenyl]-;3-(Trifluoromethyl)cinnamic acid m-(T

factory 3-(Trifluoromethyl)cinnamic acid with best price

Cas:779-89-5

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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Changchun Artel lmport and Export trade company

Superiority We can customize and synthesize products that other suppliers may not be able to provide. 1. best service, high quality and reasonable way for his produccts from many recent effective packing way.best s

99% 3-(Trifluoromethyl)cinnamic acid;CAS:779-89-5

Cas:779-89-5

Min.Order:100 Kilogram

Negotiable

Type:Trading Company

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

3-(Trifluoromethyl)Cinnamic Acid

Cas:779-89-5

Min.Order:0

Negotiable

Type:Manufacturers

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Triumph International Development Limilted

Appearance:white powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:Common products:Sea/Air/Courie

3-(trifluoromethyl)cinnamic acid

Cas:779-89-5

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Taizhou Crene Biotechnology co.ltd

Our company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-

3-(Trifluoromethyl)cinnamic acid 779-89-5

Cas:779-89-5

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

3-(TRIFLUOROMETHYL)CINNAMIC ACID

Cas:779-89-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

3-(Trifluoromethyl)cinnamic acid

Cas:779-89-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shaanxi Cuicheng Biomedical Technology Co., Ltd.

Why Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu

3-(Trifluoromethyl)cinnamic acid

Cas:779-89-5

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Synthetic route

m-trifluoromethylphenyl iodide
401-81-0

m-trifluoromethylphenyl iodide

acrylic acid methyl ester
292638-85-8

acrylic acid methyl ester

3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

Conditions
ConditionsYield
With triethylamine; di-(3-methylphenyl)phosphinopolystyrene palladium catalyst In acetonitrile at 80℃; for 20h; Heck cross-coupling reaction;96%
malonic acid
141-82-2

malonic acid

3-Trifluoromethylbenzaldehyde
454-89-7

3-Trifluoromethylbenzaldehyde

3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

Conditions
ConditionsYield
With piperidine; pyridine at 110℃;89%
piperidine In pyridine at 110 - 115℃; Knoevenagel-Doebner condensation;72%
With piperidine In pyridine at 80 - 90℃;
m-trifluoromethyl-α-bromohydrocinnamic acid
1015065-52-7

m-trifluoromethyl-α-bromohydrocinnamic acid

3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

Conditions
ConditionsYield
Stage #1: m-trifluoromethyl-α-bromohydrocinnamic acid With sodium hydroxide; water; N-benzyl-N,N,N-triethylammonium chloride In isopropyl alcohol at 55 - 60℃; for 7h;
Stage #2: With hydrogenchloride; water at 0℃;
3-Trifluoromethylbenzaldehyde
454-89-7

3-Trifluoromethylbenzaldehyde

acetic anhydride
108-24-7

acetic anhydride

3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

Conditions
ConditionsYield
at 175℃; for 5.25h;
3-Trifluoromethylbenzaldehyde
454-89-7

3-Trifluoromethylbenzaldehyde

malonic

malonic

3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

Conditions
ConditionsYield
With piperidine; pyridine at 90℃;
(E)-ethyl 3-(3-trifluoromethylphenyl)prop-2-enoate
116577-12-9, 113048-68-3

(E)-ethyl 3-(3-trifluoromethylphenyl)prop-2-enoate

3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

Conditions
ConditionsYield
With lithium hydroxide In tetrahydrofuran; ethanol; water at 20℃; for 4h;
3-Trifluoromethylbenzaldehyde
454-89-7

3-Trifluoromethylbenzaldehyde

3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: dichloromethane / 16 h / 0 - 20 °C
2: lithium hydroxide / tetrahydrofuran; ethanol; water / 4 h / 20 °C
View Scheme
3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

trans-3-(trifluoromethyl)cinnamoyl chloride
60689-14-7

trans-3-(trifluoromethyl)cinnamoyl chloride

Conditions
ConditionsYield
With thionyl chloride In dichloromethane; N,N-dimethyl-formamide Reflux; Inert atmosphere;100%
With oxalyl dichloride; calcium carbonate In N,N-dimethyl-formamide; benzene for 24h; Ambient temperature;
With thionyl chloride at 90℃; for 3h;
3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

3-(3-trifluoromethylphenyl)propanoic acid
585-50-2

3-(3-trifluoromethylphenyl)propanoic acid

Conditions
ConditionsYield
With hydrogen; palladium dihydroxide at 40 - 60℃; under 2250.23 Torr;100%
With palladium on activated charcoal; hydrogen; sodium carbonate In water at 25℃; under 1500.15 - 2250.23 Torr; for 3h;99.4%
With hydrogen; palladium on activated charcoal In methanol at 20 - 25℃; under 30.003 Torr;95.2%
3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

(E)-N,N-dimethyl-3-(3-(trifluoromethyl)phenyl)acrylamide
93040-63-2

(E)-N,N-dimethyl-3-(3-(trifluoromethyl)phenyl)acrylamide

Conditions
ConditionsYield
With hydrogenchloride; 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide In 1,4-dioxane at 120℃; for 4h;99%
methanol
67-56-1

methanol

3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

trans-methyl 3-(3-(trifluoromethyl)phenyl)acrylate
104201-66-3

trans-methyl 3-(3-(trifluoromethyl)phenyl)acrylate

Conditions
ConditionsYield
With thionyl chloride at 0℃; for 6h; Inert atmosphere; Reflux;95%
With sulfuric acid Heating;
With sulfuric acid Reflux; Acidic conditions;
With sulfuric acid Inert atmosphere; Reflux;
para-bromotoluene
106-38-7

para-bromotoluene

3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

1-(1-p-tolylvinyl)-3-(trifluoromethyl)benzene

1-(1-p-tolylvinyl)-3-(trifluoromethyl)benzene

Conditions
ConditionsYield
Stage #1: 3-(trifluoromethyl)cinnamic acid With potassium tert-butylate In ethanol at 20℃; for 1h; Inert atmosphere; Sealed tube;
Stage #2: para-bromotoluene With palladium(II) acetylacetonate; 1,10-Phenanthroline; tris-(o-tolyl)phosphine; copper(I) bromide In 1-methyl-pyrrolidin-2-one; quinoline; ethanol at 170℃; for 16h; Heck Reaction; Inert atmosphere; Sealed tube;
94%
3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

dimethyl sulfate
77-78-1

dimethyl sulfate

trans-methyl 3-(3-(trifluoromethyl)phenyl)acrylate
104201-66-3

trans-methyl 3-(3-(trifluoromethyl)phenyl)acrylate

Conditions
ConditionsYield
With N,N-dimethyl-formamide at 150℃; for 0.333333h;90.9%
With potassium carbonate In acetone Heating;
3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

(E)-3-(3-(trifluoromethyl)phenyl)acrylamide
64380-24-1

(E)-3-(3-(trifluoromethyl)phenyl)acrylamide

Conditions
ConditionsYield
Stage #1: 3-(trifluoromethyl)cinnamic acid With thionyl chloride In tetrahydrofuran at 50℃; for 1h;
Stage #2: With ammonium hydroxide In tetrahydrofuran at 0℃; for 0.0833333h;
87%
Multi-step reaction with 2 steps
1: oxalyl chloride, CaCO3 / benzene; dimethylformamide / 24 h / Ambient temperature
2: NH3(gas) / benzene / 12 h
View Scheme
p-cresol
106-44-5

p-cresol

3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

4-(3-(trifluoromethyl)phenyl)-3,4-dihydro-6-methylchromen-2-one

4-(3-(trifluoromethyl)phenyl)-3,4-dihydro-6-methylchromen-2-one

Conditions
ConditionsYield
With sulfuric acid at 110℃; for 12h; Inert atmosphere;85%
With sulfuric acid at 120℃; for 15h;80%
3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

tartaric acid
87-69-4

tartaric acid

6β-N-methylnaltrexamine
102869-99-8

6β-N-methylnaltrexamine

(2E)-N-[(5R,6R)-17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-yl]-3-(3-trifluoromethylphenyl)-N-methylprop-2-enamide tartrate

(2E)-N-[(5R,6R)-17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-yl]-3-(3-trifluoromethylphenyl)-N-methylprop-2-enamide tartrate

Conditions
ConditionsYield
Stage #1: 3-(trifluoromethyl)cinnamic acid; 6β-N-methylnaltrexamine
Stage #2: tartaric acid
84%
3-(2,4,5-trimethoxyphenyl)-(2E)-2-propen-1-ol
1392497-89-0

3-(2,4,5-trimethoxyphenyl)-(2E)-2-propen-1-ol

3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

(E)-3-(2,4,5-trimethoxyphenyl)allyl (E)-3-(3-(trifluoromethyl)phenyl)acrylate

(E)-3-(2,4,5-trimethoxyphenyl)allyl (E)-3-(3-(trifluoromethyl)phenyl)acrylate

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; Inert atmosphere;77.7%
2-(2-(piperazin-1-yl)ethyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione
66235-11-8

2-(2-(piperazin-1-yl)ethyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione

3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

(E)-2-(2-(4-(3-(3-(trifluoromethyl)phenyl)acryloyl)piperazin-1-yl)ethyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione

(E)-2-(2-(4-(3-(3-(trifluoromethyl)phenyl)acryloyl)piperazin-1-yl)ethyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 14h;75%
3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

glycine tert-butyl ester hydrochloride
27532-96-3

glycine tert-butyl ester hydrochloride

C16H18F3NO3

C16H18F3NO3

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In tetrahydrofuran; N,N-dimethyl-formamide at 20℃;69%
3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

melampomagnolide B
93930-15-5

melampomagnolide B

((1aR,7aS,10aS,10bS,E)-1a-methyl-8-methylene-9-oxo-1a,2,3,6,7,7a,8,9,10a,10b-decahydrooxireno[2',3':9,10]cyclodeca[1,2-b]furan-5-yl)methyl (E)-3-(3-(trifluoromethyl)phenyl)acrylate

((1aR,7aS,10aS,10bS,E)-1a-methyl-8-methylene-9-oxo-1a,2,3,6,7,7a,8,9,10a,10b-decahydrooxireno[2',3':9,10]cyclodeca[1,2-b]furan-5-yl)methyl (E)-3-(3-(trifluoromethyl)phenyl)acrylate

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane at 0 - 20℃; for 8h; Inert atmosphere;69%
3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

withangulatin A

withangulatin A

C40H43F3O9

C40H43F3O9

Conditions
ConditionsYield
Stage #1: 3-(trifluoromethyl)cinnamic acid With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane at 0℃; for 1h;
Stage #2: withangulatin A In dichloromethane at 25℃; for 24h;
67%
3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

sodium benzenesulfonate
873-55-2

sodium benzenesulfonate

(E)-1-(2-((phenyl)sulfonyl)vinyl)-3-trifluoromethylbenzene
1554271-74-7

(E)-1-(2-((phenyl)sulfonyl)vinyl)-3-trifluoromethylbenzene

Conditions
ConditionsYield
With [bis(acetoxy)iodo]benzene In N,N-dimethyl-formamide at 100℃; for 0.166667h;63%
3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

3-(1-methyl-1H-indol-3-yl)-3-oxopropanenitrile
343778-74-5

3-(1-methyl-1H-indol-3-yl)-3-oxopropanenitrile

2-(1-methyl-1H-indol-3-yl)-5-(3-(trifluoromethyl)phenyl)furan-3-carbonitrile

2-(1-methyl-1H-indol-3-yl)-5-(3-(trifluoromethyl)phenyl)furan-3-carbonitrile

Conditions
ConditionsYield
With di-tert-butyl peroxide; copper diacetate In dimethyl sulfoxide at 90℃; for 8h; Sealed tube; Inert atmosphere; regioselective reaction;61%
3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

2-amino-benzenethiol
137-07-5

2-amino-benzenethiol

2,3-dihydro-2-(3-trifluoromethylphenyl)-1,5-benzothiazepin-4(5H)-one

2,3-dihydro-2-(3-trifluoromethylphenyl)-1,5-benzothiazepin-4(5H)-one

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In neat (no solvent) at 80℃; for 24h; Green chemistry;57%
3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

methyllithium
917-54-4

methyllithium

(E)-4-(3-trifluoromethylphenyl)but-3-en-2-one
84175-48-4

(E)-4-(3-trifluoromethylphenyl)but-3-en-2-one

Conditions
ConditionsYield
In diethyl ether at 5 - 20℃; for 22h;54%
3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

A

(Z)-β-bromo-3-trifluoromethylstyrene
114092-60-3

(Z)-β-bromo-3-trifluoromethylstyrene

B

(E)-1-(2-bromovinyl)-3-trifluoromethylbenzene
114092-59-0

(E)-1-(2-bromovinyl)-3-trifluoromethylbenzene

Conditions
ConditionsYield
With N-Bromosuccinimide; lithium acetate In acetonitrile for 0.0333333h; microwave irradiation;A n/a
B 52%
3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

trans-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-benzyl-piperidin-4-yl)-3-(3-trifluoromethyl-phenyl)-acrylamide

trans-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-benzyl-piperidin-4-yl)-3-(3-trifluoromethyl-phenyl)-acrylamide

Conditions
ConditionsYield
52%
3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

4-phenyl-2-(2-phenylthiazol-4-yl)oxazole

4-phenyl-2-(2-phenylthiazol-4-yl)oxazole

2-phenyl-4-(6-phenyl-3-(3-(trifluoromethyl)phenyl)pyridin-2-yl)thiazole

2-phenyl-4-(6-phenyl-3-(3-(trifluoromethyl)phenyl)pyridin-2-yl)thiazole

Conditions
ConditionsYield
In 1,2-dichloro-benzene at 180℃; for 24h; Sealed tube; Inert atmosphere;51%
3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

ammonium thiocyanate
1147550-11-5

ammonium thiocyanate

(E)-1-(2-thiocyanatovinyl)-3-(trifluoromethyl)benzene

(E)-1-(2-thiocyanatovinyl)-3-(trifluoromethyl)benzene

Conditions
ConditionsYield
With ammonium acetate; sodium perchlorate; sodium hydrogencarbonate In water; acetonitrile at 20℃; for 9h; Electrolysis; Green chemistry;51%
3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

Langlois reagent
2926-29-6

Langlois reagent

1-[(E)-3,3,3-trifluoro-1-propen-1-yl]-3-trifluoromethylbenzene
78622-59-0

1-[(E)-3,3,3-trifluoro-1-propen-1-yl]-3-trifluoromethylbenzene

Conditions
ConditionsYield
With 2,2,2-trifluoroethanol; lithium perchlorate In 1,2-dimethoxyethane; water at 20℃; for 12h; Electrochemical reaction; Green chemistry; stereoselective reaction;51%
3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

(Z)-N'-hydroxybutyrimidamide
27620-10-6

(Z)-N'-hydroxybutyrimidamide

(E)-3-propyl-5-(3-(trifluoromethyl) styryl)-1,2,4-oxadiazole

(E)-3-propyl-5-(3-(trifluoromethyl) styryl)-1,2,4-oxadiazole

Conditions
ConditionsYield
Stage #1: 3-(trifluoromethyl)cinnamic acid With 1,1'-carbonyldiimidazole In toluene at 20℃;
Stage #2: (Z)-N'-hydroxybutyrimidamide In toluene at 20 - 110℃;
48.5%
meta-fluoroaniline
372-19-0

meta-fluoroaniline

3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

(E)-3-(3-(trifluoromethyl)phenyl)-N-(3-fluorophenyl)-2-propenamide

(E)-3-(3-(trifluoromethyl)phenyl)-N-(3-fluorophenyl)-2-propenamide

Conditions
ConditionsYield
Stage #1: 3-(trifluoromethyl)cinnamic acid With 4-methyl-morpholine; isobutyl chloroformate In tetrahydrofuran at -78℃; for 0.116667h;
Stage #2: meta-fluoroaniline In tetrahydrofuran at -78 - 20℃;
43%
3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

5-chloro-2-(4-methoxyphenyl)-4-phenyloxazole

5-chloro-2-(4-methoxyphenyl)-4-phenyloxazole

A

6-(4-methoxyphenyl)-2-phenyl-5-(3-(trifluoromethyl)phenyl)pyridin-3-ol

6-(4-methoxyphenyl)-2-phenyl-5-(3-(trifluoromethyl)phenyl)pyridin-3-ol

B

6-(4-methoxyphenyl)-2-phenyl-4-(3-(trifluoromethyl)phenyl)pyridin-3-ol

6-(4-methoxyphenyl)-2-phenyl-4-(3-(trifluoromethyl)phenyl)pyridin-3-ol

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine at 180℃; for 24h; Reagent/catalyst; Sealed tube; Inert atmosphere;A 43%
B 17%
3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

N1-(1,2,3,4-tetrahydroacridin-9-yl)hexane-1,6-diamine
249290-17-3

N1-(1,2,3,4-tetrahydroacridin-9-yl)hexane-1,6-diamine

(E)-N-(6-((1,2,3,4-tetrahydroacridin-9-yl)amino)hexyl)-3-(3-(trifluoromethyl)phenyl)acrylamide

(E)-N-(6-((1,2,3,4-tetrahydroacridin-9-yl)amino)hexyl)-3-(3-(trifluoromethyl)phenyl)acrylamide

Conditions
ConditionsYield
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 24h;38%
3-(trifluoromethyl)cinnamic acid
779-89-5

3-(trifluoromethyl)cinnamic acid

pinacol benzylboronate
87100-28-5

pinacol benzylboronate

C16H13F3

C16H13F3

Conditions
ConditionsYield
With silver carbonate; copper(II) oxide In dimethyl sulfoxide at 120℃; for 12h; Inert atmosphere;38%

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