CAS No.58059-31-7,3-CHLORO-6-(4-METHOXYPHENYL)-PYRIDAZINE Suppliers

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Pyridazine,3-chloro-6-(4-methoxyphenyl)-

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Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

3-CHLORO-6-(4-METHOXYPHENYL)-PYRIDAZINE

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Henan Allgreen Chemical Co.,Ltd

high qualityAppearance:white crystalline powder Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

(1S,2S)-2-[(4R,11bS)-3,5-dihydro-4H-dinaphtho[2,1-c:1',2'-e]phosphepin-4-yl]-1-phenylpropan-2-aMine, Min. 97%

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(1S,2S)-2-[(4R,11bS)-3,5-dihydro-4H-dinaphtho[2,1-c:1',2'-e]phosphepin-4-yl]-1-phenylpropan-2-aMine, Min. 97%Appearance:white crystalline powder Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Appl

(1S,2S)-2-[(4R,11bS)-3,5-dihydro-4H-dinaphtho[2,1-c:1',2'-e]phosphepin-4-yl]-1-phenylpropan-2-aMine, Min. 97%

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Hangzhou Fandachem Co.,Ltd

3-CHLORO-6-(4-METHOXYPHENYL)PYRIDAZINEAppearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

3-CHLORO-6-(4-METHOXYPHENYL)PYRIDAZINE

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ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

3-CHLORO-6-(4-METHOXYPHENYL)-PYRIDAZINE

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Jilin haofei import and export trade Co.,Ltd

Price, service, company and transport advantage: 1. Best service, place of origin China, high quality, and reasonable price. 2. It's customers' right to choose the package (EMS, DHL, FEDEX, UPS). 3. It's customers' right

(1S,2S)-2-[(4R,11bS)-3,5-dihydro-4H-dinaphtho[2,1-c:1',2'-e]phosphepin-4-yl]-1-phenylpropan-2-aMine, Min. 97% CAS NO.58059-31-7

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Finetech Industry Limited

FINETECH INDUSTRY LIMITED is a LONDON based CRO company providing drug discovery & development services to worldwide clients. FINETECH INDUSTRY LIMITED supplies the 3-Chloro-6-(4-methoxyphenyl)pyridazine, CAS:58059-31-7 with the most competitive pric

3-Chloro-6-(4-methoxyphenyl)pyridazine

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Tianjin SPHINX SCIENTIFIC LAB.

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Pyridazine,3-chloro-6-(4-methoxyphenyl)-

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Pyridazine,3-chloro-6-(4-methoxyphenyl)-

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GS-ctLab

Pyridazine,3-chloro-6-(4-methoxyphenyl)-

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BICKFORD CONSULTING KEG

PLEASE CONTACT US mbickford@sbo-consulting.com

Pyridazine,3-chloro-6-(4-methoxyphenyl)-

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Synthetic route

: 2166-33-8
6-(4-methoxyphenyl)-2H-pyridazin-3-one

: 58059-31-7
3-chloro-6-(4-methoxyphenyl)pyridazine

Conditions

Conditions	Yield
With isocyanate de chlorosulfonyle In acetonitrile at 60 - 65℃; for 3.5h;	82%
With trichlorophosphate at 85 - 95℃; for 4h;
With trichlorophosphate Heating;

: 33397-21-6
tris(4-methoxyphenyl)bismuth

: 135034-10-5
3-chloro-6-iodopyridazine

: 58059-31-7
3-chloro-6-(4-methoxyphenyl)pyridazine

Conditions

Conditions	Yield
With palladium diacetate; triphenylphosphine In N,N-dimethyl-formamide at 90℃; for 4h; Catalytic behavior; Reagent/catalyst; Inert atmosphere; chemoselective reaction;	82%

: 5720-07-0
4-methoxyphenylboronic acid

: 135034-10-5
3-chloro-6-iodopyridazine

A: 2166-07-6
3,6-bis-(4-methoxyphenyl)-pyridazine

B: 58059-31-7
3-chloro-6-(4-methoxyphenyl)pyridazine

Conditions

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0); caesium carbonate In 1,4-dioxane Suzuki Coupling; Heating; Inert atmosphere; chemoselective reaction;	A 15% B 70%

...Expand

: 141-30-0
3,6-dichlorpyridazine

: 5720-07-0
4-methoxyphenylboronic acid

: 58059-31-7
3-chloro-6-(4-methoxyphenyl)pyridazine

Conditions

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0); caesium carbonate In 1,4-dioxane Suzuki Coupling; Heating; Inert atmosphere; chemoselective reaction;	58%
With potassium phosphate tribasic trihydrate; (2-mesityl-1H-inden-3-yl)dicyclohexyl phosphine; palladium diacetate; Aliquat 336 In water at 20 - 100℃; for 8h; Suzuki-Miyaura Coupling; Inert atmosphere;	43%
With sodium carbonate; tetrakis(triphenylphosphine) palladium(0) In ethanol; water; toluene at 80℃; for 16h;

: 141-30-0
3,6-dichlorpyridazine

: 33397-21-6
tris(4-methoxyphenyl)bismuth

A: 2132-80-1
4,4'-Dimethoxybiphenyl

B: 58059-31-7
3-chloro-6-(4-methoxyphenyl)pyridazine

Conditions

Conditions	Yield
With palladium diacetate; triphenylphosphine; cesium fluoride In N,N-dimethyl-formamide at 90℃; Inert atmosphere; chemoselective reaction;	A 17 %Chromat. B 43%

...Expand

: 2166-33-8
6-(4-methoxy-phenyl)-2H-pyridazin-3-one

: 58059-31-7
3-chloro-6-(4-methoxyphenyl)pyridazine

Conditions

Conditions	Yield
With trichlorophosphate at 0℃; for 6h; Heating / reflux;	40%

: 141-30-0
3,6-dichlorpyridazine

: 93296-09-4
4-methoxyphenylzinc chloride

A: 2166-07-6
3,6-bis-(4-methoxyphenyl)-pyridazine

B: 58059-31-7
3-chloro-6-(4-methoxyphenyl)pyridazine

Conditions

Conditions	Yield
tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran at 20℃; for 24h;

...Expand

: 141-30-0
3,6-dichlorpyridazine

: 33397-21-6
tris(4-methoxyphenyl)bismuth

: 58059-31-7
3-chloro-6-(4-methoxyphenyl)pyridazine

Conditions

Conditions	Yield
With palladium diacetate; triphenylphosphine; cesium fluoride In N,N-dimethyl-formamide at 90℃; Reagent/catalyst; Inert atmosphere; chemoselective reaction;

: C11H12N2O2

: 58059-31-7
3-chloro-6-(4-methoxyphenyl)pyridazine

Conditions

Conditions	Yield
With trichlorophosphate

: 100-06-1
1-(4-methoxyphenyl)ethanone

: 58059-31-7
3-chloro-6-(4-methoxyphenyl)pyridazine

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: acetic acid / Reflux 1.2: 2 h / Reflux 2.1: trichlorophosphate / Heating View Scheme

: 38111-44-3
phenylzinc(II) bromide

: 58059-31-7
3-chloro-6-(4-methoxyphenyl)pyridazine

: 2166-04-3
3-(4-methoxyphenyl)-6-phenylpyridazine

Conditions

Conditions	Yield
tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran at 60℃;	80%

: 109-00-2
3-HYDROXYPYRIDINE

: 58059-31-7
3-chloro-6-(4-methoxyphenyl)pyridazine

: 3-hydroxy-1-<6-(4-methoxyphenyl)-3-pyridazinyl>pyridinium chloride

Conditions

Conditions	Yield
In butan-1-ol for 4h; Heating;	79.4%

: 5382-16-1
4-HYDROXYPIPERIDINE

: 58059-31-7
3-chloro-6-(4-methoxyphenyl)pyridazine

: 93181-98-7
3-(4-hydroxypiperidino)-6-(4-methoxyphenyl)pyridazine

Conditions

Conditions	Yield
In butan-1-ol for 3h; Heating;	75%

: 288-32-4
1H-imidazole

: 58059-31-7
3-chloro-6-(4-methoxyphenyl)pyridazine

: 3-(1H-imidazol-1-yl)-6-(4-methoxyphenyl)pyridazine

Conditions

Conditions	Yield
Stage #1: 1H-imidazole With sodium hydride In N,N-dimethyl-formamide; mineral oil at 20℃; for 1h; Stage #2: 3-chloro-6-(4-methoxyphenyl)pyridazine In N,N-dimethyl-formamide; mineral oil at 100℃; for 6h;	60%

: 1068-57-1
acetic acid hydrazide

: 58059-31-7
3-chloro-6-(4-methoxyphenyl)pyridazine

: 76970-05-3
6-(4-Methoxy-phenyl)-3-methyl-[1,2,4]triazolo[4,3-b]pyridazine

Conditions

Conditions	Yield
In butan-1-ol for 48h; Heating;	51%

: 624-84-0
formic acid hydrazide

: 58059-31-7
3-chloro-6-(4-methoxyphenyl)pyridazine

: 117979-38-1
6-(4-methoxyphenyl)-1,2,4-triazolo<4,3-b>pyridazine

Conditions

Conditions	Yield
With triethylamine hydrochloride In xylene for 2h; Heating / reflux;	27%

: 58059-31-7
3-chloro-6-(4-methoxyphenyl)pyridazine

: 22042-73-5
4-(2-hydroxy-ethoxy)-benzaldehyde

: 935692-89-0
4-{2-[6-(4-methoxy-phenyl)-pyridazin-3-yloxy]-ethoxy}-benzaldehyde

Conditions

Conditions	Yield
Stage #1: 4-(2-hydroxy-ethoxy)-benzaldehyde With sodium In tetrahydrofuran at 60℃; for 2h; Stage #2: 3-chloro-6-(4-methoxyphenyl)pyridazine In tetrahydrofuran for 10h; Heating / reflux;	9%

: 58059-31-7
3-chloro-6-(4-methoxyphenyl)pyridazine

: 18772-76-4
3-hydrazino-6-(p-methoxyphenyl)pyridazine

Conditions

Conditions	Yield
With hydrazine hydrate In butan-1-ol at 100℃; for 6h;

: 58059-31-7
3-chloro-6-(4-methoxyphenyl)pyridazine

: 6-endo-cyano-8-<6-(4-methoxyphenyl)-3-pyridazinyl>-8-azabicyclo<3.2.1>oct-3-en-2-one

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 79.4 percent / butan-1-ol / 4 h / Heating 2: Et3N 3: 45 percent / hydroquinone / acetonitrile / 48 h / Heating View Scheme

: 58059-31-7
3-chloro-6-(4-methoxyphenyl)pyridazine

: 6-endo-phenyl-8-<6-(4-methoxyphenyl)-3-pyridazinyl>-8-azabicyclo<3.2.1>oct-3-en-2-one

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 79.4 percent / butan-1-ol / 4 h / Heating 2: 40 percent / Et3N, hydroquinone / 48 h / Heating View Scheme

: 58059-31-7
3-chloro-6-(4-methoxyphenyl)pyridazine

: (1R,2S,6R,7R)-3,11-Bis-[6-(4-methoxy-phenyl)-pyridazin-3-yl]-3,11-diaza-tricyclo[5.3.1.12,6]dodeca-4,9-diene-8,12-dione

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 79.4 percent / butan-1-ol / 4 h / Heating 2: Et3N View Scheme

: 58059-31-7
3-chloro-6-(4-methoxyphenyl)pyridazine

: 3-hydroxy-1-<6-(4-methoxyphenyl)-3-pyridazinyl>pyridinium maleate

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 79.4 percent / butan-1-ol / 4 h / Heating 2: Et3N 3: 91 percent / tetrahydrofuran / 14 h / Heating View Scheme

: 58059-31-7
3-chloro-6-(4-methoxyphenyl)pyridazine

: 3-hydroxy-1-<6-(4-methoxyphenyl)-3-pyridazinyl>pyridinium fumarate

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 79.4 percent / butan-1-ol / 4 h / Heating 2: Et3N 3: 85 percent / dioxane / 14 h / Heating View Scheme

: 58059-31-7
3-chloro-6-(4-methoxyphenyl)pyridazine

: 104104-50-9
2-(3-carboxypropyl)-3-amino-6-(4-methoxyphenyl)pyridazinium bromide

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: hydrazine hydrate / butan-1-ol / 6 h / 100 °C 2: H2 / Raney Ni / methanol / 20 °C / 760 Torr 3: dimethylformamide / 8 h / 80 °C 4: 48percent HBr / acetic acid / 10 h / 100 °C View Scheme

: 58059-31-7
3-chloro-6-(4-methoxyphenyl)pyridazine

: 105538-31-6
6-Amino-1-(3-ethoxycarbonyl-propyl)-3-(4-methoxy-phenyl)-pyridazin-1-ium; bromide

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: hydrazine hydrate / butan-1-ol / 6 h / 100 °C 2: H2 / Raney Ni / methanol / 20 °C / 760 Torr 3: dimethylformamide / 8 h / 80 °C View Scheme

: 58059-31-7
3-chloro-6-(4-methoxyphenyl)pyridazine

: 4776-87-8
3-amino-6-(4'-methoxyphenyl)pyridazine

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: hydrazine hydrate / butan-1-ol / 6 h / 100 °C 2: H2 / Raney Ni / methanol / 20 °C / 760 Torr View Scheme

: 58059-31-7
3-chloro-6-(4-methoxyphenyl)pyridazine

: 99708-46-0
3-chloro-6-(4-hydroxyphenyl)pyridazine

Conditions

Conditions	Yield
With boron tribromide In dichloromethane at 20℃; for 16h;

: 3291-03-0
3,4,5-trimethoxybenzohydrazide

: 58059-31-7
3-chloro-6-(4-methoxyphenyl)pyridazine

: 3-(3,4,5-trimethoxyphenyl)-6-(4-methoxyphenyl)-[1,2,4]triazolo[4,3-b]pyridazine

Conditions

Conditions	Yield
In butan-1-ol Heating; Microwave irradiation;

: 1153791-73-1
C10H14N2O4

: 58059-31-7
3-chloro-6-(4-methoxyphenyl)pyridazine

: 3-(2,3,4-trimethoxyphenyl)-6-(4-methoxyphenyl)-[1,2,4]triazolo[4,3-b]pyridazine

Conditions

Conditions	Yield
In butan-1-ol Heating; Microwave irradiation;

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Jilin haofei import and export trade Co.,Ltd

Finetech Industry Limited

Tianjin SPHINX SCIENTIFIC LAB.

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Synthetic route

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