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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

2-Hydroxy-4-(methylthio)butanoic acid Manufacturer/High quality/Best price/In stock

Cas:583-91-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2-Hydroxy-4-(methylthio)butanoic acid

Cas:583-91-5

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% 583-91-5 2-Hydroxy-4-(methylthio)butyric Acid Manufacturer

Cas:583-91-5

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermedi

Desmeninol

Cas:583-91-5

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Methionine hydroxy analogue

Cas:583-91-5

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

2-HYDROXY-4-(METHYLTHIO)BUTYRIC ACID

Cas:583-91-5

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Henan Tianfu Chemical Co., Ltd.

Our company engages in Sodium Tripolyphosphate (STPP) and Sodium Hexametabphosphate (SHMP) production; development of noble metal catalysts, synthesis of electronic chemical materials and general chemicals Imp&Exp trading business. The company

TIANFU-CHEM - 2-HYDROXY-4-(METHYLTHIO)BUTYRIC ACID

Cas:583-91-5

Min.Order:1 Kilogram

FOB Price: $1000.0

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 583-91-5 with competitive price

Cas:583-91-5

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

2-HYDROXY-4-(METHYLTHIO)BUTYRIC ACID factory price

Cas:583-91-5

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2-Hydroxy-4-(methylthio)butanoic acid 583-91-5

Cas:583-91-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

Empagliflozin CAS:864070-44-0 2-HYDROXY-4-(METHYLTHIO)BUTYRIC ACID CAS:583-91-5Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates

2-HYDROXY-4-(METHYLTHIO)BUTYRIC ACID CAS:583-91-5

Cas:583-91-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2-Hydroxy-4-(methylthio)butanoic acid

Cas:583-91-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hebei Mojin Biotechnology Co.,Ltd

Hebei Mojin Biotechnology Co., Ltd, Our company is a professional chemical raw materials and chemical reagents research and development production enterprises. We have several production line,So we can control the lowest price. We also have several

2-Hydroxy-4-(methylthio)butyric Acid cas:583-91-5

Cas:583-91-5

Min.Order:25 Gram

FOB Price: $90.0 / 100.0

Type:Trading Company

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Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

2-HYDROXY-4-(METHYLTHIO)BUTYRIC ACID

Cas:583-91-5

Min.Order:1 Kilogram

FOB Price: $80.0 / 100.0

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

2-Hydroxy-4-(methylthio)butanoic acid

Cas:583-91-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

MHA

Cas:583-91-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2-Hydroxy-4-(methylthio)butanoic acid

Cas:583-91-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 2-Hydroxy-4-(methylthio)butanoic acid

Cas:583-91-5

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:Light brown liquid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:100g/bottle,1kg/bottle,25kg/drum or as per your request Application:Methionine h

2-Hydroxy-4-(methylthio)butanoic acid

Cas:583-91-5

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

2-HYDROXY-4-(METHYLTHIO)BUTYRIC ACID

Cas:583-91-5

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

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Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

2-Hydroxy-4-(methylthio)butanoic acid

Cas:583-91-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Buy Top Purity 2-HYDROXY-4-(METHYLTHIO)BUTYRIC ACID

Cas:583-91-5

Min.Order:0

Negotiable

Type:Trading Company

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EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

TIANFUCHEM--High purity 2-HYDROXY-4-(METHYLTHIO)BUTYRIC ACID factory price

Cas:583-91-5

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

2-HYDROXY-4-(METHYLTHIO)BUTYRIC ACID

Cas:583-91-5

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

TIANFUCHEM--High purity 2-HYDROXY-4-(METHYLTHIO)BUTYRIC ACID factory price

Cas:583-91-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

TIANFUCHEM--High purity 2-HYDROXY-4-(METHYLTHIO)BUTYRIC ACID factory price

Cas:583-91-5

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

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Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Business Custom Synthesis:

2-Hydroxy-4-(methylthio)butanoic acid

Cas:583-91-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe

SAGECHEM/2-Hydroxy-4-(methylthio)butyric acid

Cas:583-91-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

2-HYDROXY-4-(METHYLTHIO)BUTYRIC ACID

Cas:583-91-5

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

TIANFUCHEM--High purity 2-HYDROXY-4-(METHYLTHIO)BUTYRIC ACID factory price

Cas:583-91-5

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Synthetic route

3-hydroxyoxolan-2-one
19444-84-9

3-hydroxyoxolan-2-one

sodium thiomethoxide
5188-07-8

sodium thiomethoxide

2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

Conditions
ConditionsYield
Stage #1: 3-hydroxyoxolan-2-one; sodium thiomethoxide In N,N-dimethyl-formamide at 153℃; for 3h;
Stage #2: With hydrogenchloride; water Product distribution / selectivity;
100%
2-hydroxy-4-(methylthio)butyronitrile
17773-41-0

2-hydroxy-4-(methylthio)butyronitrile

2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

Conditions
ConditionsYield
With potassium phosphate buffer; nitrilase from Alcaligenes faecalis ATCC8750 at 30℃; for 48h; pH=7.3;99%
Multi-step reaction with 2 steps
1: 83 percent / borax / KCN / H2O / 1.5 h / 80 °C
2: 90 percent / NaOH / H2O / 3 h / Heating
View Scheme
Stage #1: 2-hydroxy-4-(methylthio)butyronitrile With sulfuric acid at 65℃;
Stage #2: With water
α-hydroxy-4-methylthiobutyramide
49540-21-8

α-hydroxy-4-methylthiobutyramide

2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

Conditions
ConditionsYield
With sodium hydroxide In water for 3h; Heating;90%
With sulfuric acid; water at 110℃; for 250 - 500h; Product distribution / selectivity;
With sulfuric acid; water at 100 - 105℃; Temperature;
phosphoric acid 1,1-dicyano-3-methylsulfanyl-propyl ester diethyl ester

phosphoric acid 1,1-dicyano-3-methylsulfanyl-propyl ester diethyl ester

2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

Conditions
ConditionsYield
With hydrogenchloride for 5h; Heating;85%
methylthiol
74-93-1

methylthiol

vinyl glycolic acid
600-17-9

vinyl glycolic acid

2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

Conditions
ConditionsYield
With triethyl borane at 20℃; UV-irradiation;85%
2-hydroxy-4-(methylthio)butanoic acid calcium salt

2-hydroxy-4-(methylthio)butanoic acid calcium salt

sulfuric acid
7664-93-9

sulfuric acid

2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

Conditions
ConditionsYield
In water for 1.5h;85%
2-hydroxy-4-(methylthio)butyronitrile
17773-41-0

2-hydroxy-4-(methylthio)butyronitrile

A

α-hydroxy-4-methylthiobutyramide
49540-21-8

α-hydroxy-4-methylthiobutyramide

B

2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

Conditions
ConditionsYield
With borax; potassium cyanide In water at 80℃; for 1.5h;A 83%
B 8%
With sulfuric acid; water at 35 - 112℃; for 1.5 - 3.16667h; Product distribution / selectivity;
With sulfuric acid; water at 40 - 125℃; under 1875.19 Torr; for 2.25h; Product distribution / selectivity;
With sulfuric acid; water at 50 - 110℃; under 12 Torr; Product distribution / selectivity; Continuous process;
hydrogen cyanide
74-90-8

hydrogen cyanide

3-(methylsulfenyl)propanal
3268-49-3

3-(methylsulfenyl)propanal

A

2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

B

DL-methionine
59-51-8

DL-methionine

Conditions
ConditionsYield
With cerium(IV) oxide; ammonia In water at 75℃; for 6h;A 62.1%
B 34.9%
With cerium(IV) oxide; ammonia In water at 75℃; for 6h;A 44.3%
B 52.6%
4-(methylthio)-2-oxo-1-butanol
1003880-00-9

4-(methylthio)-2-oxo-1-butanol

2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

Conditions
ConditionsYield
Stage #1: 4-(methylthio)-2-oxo-1-butanol With potassium hydroxide; oxygen; copper diacetate In water at 20℃; for 2h;
Stage #2: With sulfuric acid; water
46%
DL-methionine
59-51-8

DL-methionine

2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

Conditions
ConditionsYield
With silver(I) nitrite; water
L-methionine
63-68-3

L-methionine

2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

Conditions
ConditionsYield
With cis-nitrous acid; sodium bromide In water at 25℃; Rate constant;
2-acetoxy-4-methylthiobutanenitrile

2-acetoxy-4-methylthiobutanenitrile

A

2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

B

2-acetyloxy-4-(methylthio)butanoic acid
138128-01-5

2-acetyloxy-4-(methylthio)butanoic acid

Conditions
ConditionsYield
With potassium phosphate buffer; nitrilase from Alcaligenes faecalis ATCC8750 at 30℃; for 48h; pH=7.3; Title compound not separated from byproducts;A 6 % Spectr.
B 82 % Spectr.
hydrogen cyanide
74-90-8

hydrogen cyanide

3-(methylsulfenyl)propanal
3268-49-3

3-(methylsulfenyl)propanal

2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

Conditions
ConditionsYield
In water at 20 - 68℃; for 0.0833333h; pH=4.7 - 5.5;
Stage #1: hydrogen cyanide; 3-(methylsulfenyl)propanal With pyridine; acetic acid at 35 - 45℃; for 1.25h;
Stage #2: With sulfuric acid; water at 60 - 90℃; for 2.91667h;
2-acetyloxy-4-(methylthio)butanoic acid
138128-01-5

2-acetyloxy-4-(methylthio)butanoic acid

A

brucine salt

brucine salt

B

2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

Conditions
ConditionsYield
With brucine In ethanol
1-acetyloxy-3-methylthiopropene

1-acetyloxy-3-methylthiopropene

(PPh3)2 PdCl2

(PPh3)2 PdCl2

L-menthoxyethyl acetyl-L-2-hydroxy-4-methylthiobutyrate

L-menthoxyethyl acetyl-L-2-hydroxy-4-methylthiobutyrate

2-(2-isopropyl-5-methylcyclohexyloxy)ethanol

2-(2-isopropyl-5-methylcyclohexyloxy)ethanol

2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

Conditions
ConditionsYield
With hydrogenchloride; CO In tetrahydrofuran
1-carboxy-3-methylthiopropyl sulfate

1-carboxy-3-methylthiopropyl sulfate

2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

Conditions
ConditionsYield
With water at 80℃; for 24h; Purification / work up;
α-hydroxy-4-methylthiobutyramide
49540-21-8

α-hydroxy-4-methylthiobutyramide

A

1-carboxy-3-methylthiopropyl sulfate

1-carboxy-3-methylthiopropyl sulfate

B

2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

Conditions
ConditionsYield
With sulfuric acid; water at 109℃; for 4h; Heating / reflux;
2-hydroxy-4-methylthiobutyric acid ammonium salt
63302-72-7

2-hydroxy-4-methylthiobutyric acid ammonium salt

2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

Conditions
ConditionsYield
In water; 4-methyl-2-pentanone at 80 - 117℃; Product distribution / selectivity; Inert atmosphere;
sodium α-keto-(γ-methylthio)butyrate
51828-97-8

sodium α-keto-(γ-methylthio)butyrate

2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

Conditions
ConditionsYield
With hydrogen; rhodium contaminated with carbon In water at 50℃; under 7500.75 Torr; for 6h; Product distribution / selectivity; autoclave;
sodium cyanide
773837-37-9

sodium cyanide

3-(methylsulfenyl)propanal
3268-49-3

3-(methylsulfenyl)propanal

3-(methylselenyl)-propanal
119353-03-6

3-(methylselenyl)-propanal

A

DL-α-hydroxyselenomethionine
873660-49-2

DL-α-hydroxyselenomethionine

B

2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

Conditions
ConditionsYield
Stage #1: 3-(methylsulfenyl)propanal; 3-(methylselenyl)-propanal With sodium hydrogensulfite In water at 20℃; for 0.166667h;
Stage #2: sodium cyanide In water at 20℃; for 2h; Reflux;
Stage #3: With hydrogenchloride; water for 5h; Reflux;
methyl 2-hydroxy-4-(methylthio)butanoate
52703-96-5

methyl 2-hydroxy-4-(methylthio)butanoate

A

methylthiol
74-93-1

methylthiol

B

2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

Conditions
ConditionsYield
With sodium hydrosulfide monohydrate In dimethyl sulfoxide at 50℃; for 24h; Temperature; Inert atmosphere; Schlenk technique;A n/a
B 93 %Spectr.
2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

2-hydroxy-4-(methylthio)butanoic acid calcium salt

2-hydroxy-4-(methylthio)butanoic acid calcium salt

Conditions
ConditionsYield
With calcium oxide In ethanol at 100℃; for 24h; Reagent/catalyst;98.09%
Stage #1: 2-hydroxy 4-methylthiobutyric acid With sodium hydroxide In water at 20℃; pH=~ 9.0;
Stage #2: With calcium chloride In water at 20℃; for 5.5h;
84%
With calcium oxide In water at 120℃; Reagent/catalyst; Temperature;
Multi-step reaction with 2 steps
1.1: sodium hydroxide / 0.5 h / 20 °C
2.1: sodium hydroxide; water / 45 - 50 °C
2.2: 0.5 h
View Scheme
Multi-step reaction with 2 steps
1.1: potassium hydroxide / methanol / 1 h / 0 °C
1.2: 0 °C
2.1: sodium hydroxide; water / 45 - 50 °C
2.2: 0.5 h
View Scheme
2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

trichloromethyl chloroformate
503-38-8

trichloromethyl chloroformate

5-(2-(methylthio)ethyl)-1,3-dioxolan-2,4-dione
1161721-72-7

5-(2-(methylthio)ethyl)-1,3-dioxolan-2,4-dione

Conditions
ConditionsYield
In tetrahydrofuran97%
methanol
67-56-1

methanol

2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

methyl 2-hydroxy-4-(methylthio)butanoate
52703-96-5

methyl 2-hydroxy-4-(methylthio)butanoate

Conditions
ConditionsYield
With sodium hydroxide at 20℃; for 0.5h;91.7%
2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

methyl p-toluene sulfonate
80-48-8

methyl p-toluene sulfonate

methyl 2-hydroxy-4-(methylthio)butanoate
52703-96-5

methyl 2-hydroxy-4-(methylthio)butanoate

Conditions
ConditionsYield
Stage #1: 2-hydroxy 4-methylthiobutyric acid With potassium hydroxide In ethanol at 20℃; for 0.5h;
Stage #2: methyl p-toluene sulfonate In ethanol at 20℃;
90.3%
2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

carbonic acid dimethyl ester
616-38-6

carbonic acid dimethyl ester

methyl 2-hydroxy-4-(methylthio)butanoate
52703-96-5

methyl 2-hydroxy-4-(methylthio)butanoate

Conditions
ConditionsYield
Stage #1: 2-hydroxy 4-methylthiobutyric acid With potassium hydroxide In methanol at 0℃; for 1h;
Stage #2: carbonic acid dimethyl ester In methanol at 0℃;
90.1%
2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

2,2-dimethoxy-propane
77-76-9

2,2-dimethoxy-propane

2,2-dimethyl-5-(2-(methylthio)ethyl)-1,3-dioxolan-4-one
1161721-65-8

2,2-dimethyl-5-(2-(methylthio)ethyl)-1,3-dioxolan-4-one

Conditions
ConditionsYield
In tetrahydrofuran89%
BF3.2H2O

BF3.2H2O

2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

MgBr2.2Et2O

MgBr2.2Et2O

2,2-dimethyl-5-(2-(methylthio)ethyl)-1,3-dioxolan-4-one
1161721-65-8

2,2-dimethyl-5-(2-(methylthio)ethyl)-1,3-dioxolan-4-one

Conditions
ConditionsYield
zinc(II) chloride In diethyl ether; water; acetone87%
dichlorotricarbonylruthenium(II) dimer

dichlorotricarbonylruthenium(II) dimer

2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

Ru(CO)3Cl2(H3CS(CH2)2CH(OH)CO2H)

Ru(CO)3Cl2(H3CS(CH2)2CH(OH)CO2H)

Conditions
ConditionsYield
In acetone at 20℃; for 24h; Inert atmosphere; Schlenk technique;83%
2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

tetradecanoyl chloride
112-64-1

tetradecanoyl chloride

A

C14-HE

C14-HE

B

C14-HE

C14-HE

Conditions
ConditionsYield
at 65℃; Overall yield = 2.6 g;A 80.5%
B 19.5%
Triisopropyl borate
5419-55-6

Triisopropyl borate

2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

D,L-2-hydroxy-4-(methylthio)-butanoic acid isopropyl ester
57296-04-5

D,L-2-hydroxy-4-(methylthio)-butanoic acid isopropyl ester

Conditions
ConditionsYield
at 95℃; for 10h;72%
2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

n-octanoic acid chloride
111-64-8

n-octanoic acid chloride

A

C8-HE

C8-HE

B

C8-HE

C8-HE

C

C8-HE

C8-HE

Conditions
ConditionsYield
at 65℃;A 25.6%
B 5.3%
C 68.4%
2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

hexan-1-ol
111-27-3

hexan-1-ol

2-hydroxy-4-(methylthio)butanoic acid hexyl ester
161193-00-6

2-hydroxy-4-(methylthio)butanoic acid hexyl ester

Conditions
ConditionsYield
With sodium hydrogen sulfate In toluene for 5.5h; Dean-Stark; Reflux;64.1%
With sodium hydrogen sulfate In toluene Dean-Stark; Reflux;61.1%
2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

acetyl chloride
75-36-5

acetyl chloride

2-acetyloxy-4-(methylthio)butanoic acid
138128-01-5

2-acetyloxy-4-(methylthio)butanoic acid

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃;63.1%
Stage #1: 2-hydroxy 4-methylthiobutyric acid With triethylamine In dichloromethane at 0℃;
Stage #2: acetyl chloride In dichloromethane at 0 - 20℃;
63.1%
With triethylamine In dichloromethane at 0 - 20℃;
at 20℃; for 3h; Temperature; Large scale;
2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

butan-1-ol
71-36-3

butan-1-ol

2-hydroxy-4-(methylthio)butanoic acid butyl ester

2-hydroxy-4-(methylthio)butanoic acid butyl ester

Conditions
ConditionsYield
With sodium hydrogen sulfate In toluene for 5h; Dean-Stark; Reflux;62.3%
1-octadecanol
112-92-5

1-octadecanol

2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

octadecyl 2-hydroxy-4-(methylthio)butanoate
1446404-60-9

octadecyl 2-hydroxy-4-(methylthio)butanoate

Conditions
ConditionsYield
With sodium hydrogen sulfate In toluene Dean-Stark; Reflux;61%
Isopropyl acetate
108-21-4

Isopropyl acetate

2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

D,L-2-hydroxy-4-(methylthio)-butanoic acid isopropyl ester
57296-04-5

D,L-2-hydroxy-4-(methylthio)-butanoic acid isopropyl ester

Conditions
ConditionsYield
With sulfuric acid at 80 - 90℃; for 6h; Temperature; Reagent/catalyst; Large scale;57.5%
2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

butanone
78-93-3

butanone

2-ethyl-2-methyl-5-(2-(methylthio)ethyl)-1,3-dioxolan-4-one
1161721-66-9

2-ethyl-2-methyl-5-(2-(methylthio)ethyl)-1,3-dioxolan-4-one

Conditions
ConditionsYield
56%
octanol
111-87-5

octanol

2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

2-hydroxy-4-(methylthio)butanoic acid octyl ester
1446404-55-2

2-hydroxy-4-(methylthio)butanoic acid octyl ester

Conditions
ConditionsYield
With sodium hydrogen sulfate In toluene Dean-Stark; Reflux;45%
With sodium hydrogen sulfate In toluene for 5.5h; Dean-Stark; Reflux;45%
2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

n-hexadecanoyl chloride
112-67-4

n-hexadecanoyl chloride

4-(methylthio)-2-(palmitoyloxy)butanoic acid

4-(methylthio)-2-(palmitoyloxy)butanoic acid

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane at 0 - 20℃;45%
1-Decanol
112-30-1

1-Decanol

2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

2-hydroxy-4-(methylthio)butyric acid decyl ester
161193-01-7

2-hydroxy-4-(methylthio)butyric acid decyl ester

Conditions
ConditionsYield
With sodium hydrogen sulfate In toluene for 6h; Reflux;44%
With sodium hydrogen sulfate In toluene Dean-Stark; Reflux;43.5%
With sodium hydrogen sulfate In toluene for 6h; Dean-Stark;43.5%
1-dodecyl alcohol
112-53-8

1-dodecyl alcohol

2-hydroxy 4-methylthiobutyric acid
583-91-5

2-hydroxy 4-methylthiobutyric acid

dodecyl 2-hydroxy-4-(methylthio)butanoate
1446404-58-5

dodecyl 2-hydroxy-4-(methylthio)butanoate

Conditions
ConditionsYield
With sodium hydrogen sulfate In toluene Dean-Stark; Reflux;42%

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