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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

2-Chloro-6-fluorobenzonitrile Manufacturer/High quality/Best price/In stock

Cas:668-45-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2-Chloro-6-Fluorobenzonitrile with high purity

Cas:668-45-1

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Henan Allgreen Chemical Co.,Ltd

T he company has advanced technology, as well as a large number of excellent R & D team, to provide customers from the grams to one hundred kilograms and tons of high-quality products, competitive prices and quality service Appearance:W

2-Chloro-6-fluorobenzonitrile

Cas:668-45-1

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermedi

2-Chloro-6-fluorobenzonitrile

Cas:668-45-1

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-Chloro-6-fluorobenzonitrile

Cas:668-45-1

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

2-Fluoro-6-Chlorobenzonitrile 668-45-1

Cas:668-45-1

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Benzonitrile,2-chloro-6-fluoro- Our company was built in 2009 with an ISO certificate.In the past 8 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Th

668-45-1 Benzonitrile,2-chloro-6-fluoro-

Cas:668-45-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 668-45-1 with fast shipping

Cas:668-45-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Product name: 2-Chloro-6-Fluorobenzonitrile CAS No.: 668-45-1 Molecular formula: C7H3ClFN Molecular weight: 155.56 Structural formula:

2-Chloro-6-Fluorobenzonitrile

Cas:668-45-1

Min.Order:5 Metric Ton

FOB Price: $1.0 / 5.0

Type:Other

inquiry

Shijiazhuang Sdyano Fine Chemical Co., Ltd

1. Best prices with satisfied quality; 2. It's clients' right to choose the package's Courier (EMS, DHL, FedEx, UPS); 3.It's clients' right to choose the packing way for his produccts from many recent effective packing w

2-Chloro-6-fluorobenzonitrile

Cas:668-45-1

Min.Order:0 Metric Ton

Negotiable

Type:Trading Company

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:powder Storage:Store in sealed containers at cool & dry pla

2-Chloro-6-fluorobenzonitrile cas no 668-45-1

Cas:668-45-1

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Benzonitrile,2-chloro-6-fluoro- 668-45-1

Cas:668-45-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

2-Fluoro-6-Chlorobenzonitrile CAS:668-45-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality orga

2-Fluoro-6-Chlorobenzonitrile CAS:668-45-1

Cas:668-45-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:668-45-1

Cas:668-45-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

2-Chloro-6-fluorobenzonitrile

Cas:668-45-1

Min.Order:1 Kilogram

FOB Price: $10.0 / 20.0

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2-Chloro-6-Fluorobenzonitrile

Cas:668-45-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2-Chloro-6-fluorobenzonitrile

Cas:668-45-1

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2-Chloro-6-fluorobenzonitrile

Cas:668-45-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2-Chloro-6-fluorobenzonitrile

Cas:668-45-1

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

2-Chloro-6-fluorobenzonitrile CAS NO.668-45-1

Cas:668-45-1

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

2-Chloro-6-fluorobenzonitrile

Cas:668-45-1

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

2-Chloro-6-fluorobenzonitrile

Cas:668-45-1

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: 2-Chloro-6-Fluorobenzonitrile CAS No.:668-45-1 Molecule Formula:C9H7FO2 Molecule Weight:166.15 Purity: 99.0% Package: 25kg/drum Description:White crystalline powder Manufacture Standards:Enterprise Standard

Best Quality 2-Chloro-6-Fluorobenzonitrile with good supplier

Cas:668-45-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

2-Chloro-6-fluorobenzonitrile

Cas:668-45-1

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

2-Chloro-6-fluorobenzonitrile Basic information Product Name: 2-Chloro-6-fluorobenzonitrile Synonyms: AKOS BBS-00006480;LABOTEST-BB LT00159627;2-CHLORO-6-FLUOROBENZONITRILE;6-Chloro-2-Fluorobenzonitrile;2-CHLORO-6-FLUOROBENZONITRILE 99% (H&amp

2-Chloro-6-fluorobenzonitrile

Cas:668-45-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

2-Chloro-6-fluorobenzonitrile

Cas:668-45-1

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

2-Chloro-6-fluorobenzonitrile

Cas:668-45-1

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

2-Chloro-6-fluorobenzonitrile

Cas:668-45-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

2-Chloro-6-fluorobenzonitrile

Cas:668-45-1

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service and h

Benzonitrile,2-chloro-6-fluoro-

Cas:668-45-1

Min.Order:0

Negotiable

Type:Other

inquiry

Synthetic route

N-[(2-chloro-6-fluorophenyl)methylidene]hydroxylamine
443-33-4

N-[(2-chloro-6-fluorophenyl)methylidene]hydroxylamine

2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

Conditions
ConditionsYield
With trifluoromethylsulfonic anhydride; triethylamine; triphenylphosphine In dichloromethane at 0℃; for 0.166667h;96%
With 1,1,3,3-tetraphenyl-2-oxa-1,3-phoshpinobenzene bis(trifluoromethanesulfonate); triethylamine In dichloromethane at 20℃; for 0.333333h;96%
Stage #1: N-[(2-chloro-6-fluorophenyl)methylidene]hydroxylamine With bis(trichloromethyl) carbonate; N,N-dimethyl-formamide In acetonitrile at 20℃; for 0.166667h;
Stage #2: With water; sodium hydrogencarbonate In acetonitrile
94%
With [PdCl2{κ2-(P,N)-2-Ph2PC6H4CH=NOH}] In acetonitrile at 100℃; for 24h; Inert atmosphere; Sealed tube;91%
With C24H33ClF3N3Os In acetonitrile at 80℃; for 1h; Sealed tube;82%
2-chloro-6-nitrobenzonitrile
6575-07-1

2-chloro-6-nitrobenzonitrile

2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

Conditions
ConditionsYield
With biphenyl; tetramethylammonium hydrogen difluoride In N,N-dimethyl acetamide at 60℃; for 3h;84%
With potassium fluoride; tetraphenylphosphonium bromide at 82℃; The ratio of the initial rates of flurine transfer reaction with KF alone and KF-Ph4PBr were measured in CH3CN and sulpholane.;
With potassium fluoride In dimethyl sulfoxide at 82℃; solvent effect of nucleophilie fluorine transfer, var. chloro-nitrobenzene;
2-chloro-6-nitrobenzonitrile
6575-07-1

2-chloro-6-nitrobenzonitrile

A

2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

B

2,6 difluorobenzonitrile
1897-52-5

2,6 difluorobenzonitrile

Conditions
ConditionsYield
With biphenyl; tetramethylammonium fluoride In N,N-dimethyl acetamide at 60℃; for 0.666667h;A 72%
B 5%
With tetrabutyl ammonium fluoride In tetrahydrofuran for 1.5h; Ambient temperature;A 75 % Chromat.
B 25 % Chromat.
2-chloro-6-nitrobenzonitrile
6575-07-1

2-chloro-6-nitrobenzonitrile

A

2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

B

2,6 difluorobenzonitrile
1897-52-5

2,6 difluorobenzonitrile

C

3-chloro-2-cyanophenol
89999-90-6

3-chloro-2-cyanophenol

D

2-Fluoro-6-hydroxybenzonitrile
140675-43-0

2-Fluoro-6-hydroxybenzonitrile

Conditions
ConditionsYield
With tetramethylammonium fluoride In dimethyl sulfoxide at 100℃; for 1h; Fluorination;
2,6-dichloro-benzonitrile
1194-65-6

2,6-dichloro-benzonitrile

A

2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

B

2,6 difluorobenzonitrile
1897-52-5

2,6 difluorobenzonitrile

Conditions
ConditionsYield
With potassium fluoride; 1-butyl-3-methylimidazolium tetrafluoroborate In sulfolane at 180℃; for 18h; Product distribution / selectivity;A 45 %Chromat.
B 52 %Chromat.
1-butyl-3-methylimidazolium hexafluorophosphate In sulfolane at 180℃; for 18h; Product distribution / selectivity;A 79 %Chromat.
B 19 %Chromat.
2-chloro-6-nitrobenzonitrile
6575-07-1

2-chloro-6-nitrobenzonitrile

Ph4 P+ HF

Ph4 P+ HF

2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

Conditions
ConditionsYield
In dimethyl sulfoxide
2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

3-chloro-2-cyanophenol
89999-90-6

3-chloro-2-cyanophenol

Conditions
ConditionsYield
With 2-(methylsulfonyl)ethyl alcohol; sodium hydride In tetrahydrofuran at 20℃; for 0.5h;100%
Stage #1: 2-chloro-6-fluorobenzonitrile With 18-crown-6 ether; potassium tert-butylate In acetonitrile Inert atmosphere; Reflux;
Stage #2: With sodium hydroxide In water; acetonitrile for 1h;
Stage #3: In water pH=4; Acidic conditions;
60%
With 18-crown-6 ether; potassium acetate In acetonitrile for 24h; Heating;2.20 g
2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

phenol
108-95-2

phenol

2-chloro-6-phenyloxybenzonitrile
91692-70-5

2-chloro-6-phenyloxybenzonitrile

Conditions
ConditionsYield
With potassium carbonate In dimethyl sulfoxide at 190℃; for 0.1h; Microwave irradiation; Sealed tube;97%
With potassium carbonate In dimethyl sulfoxide at 190℃; for 0.1h; Microwave irradiation; Sealed tube;97%
With potassium fluoride on basic alumina; 18-crown-6 ether In dimethyl sulfoxide at 140℃; for 20h;90%
3-methoxy-1-iodobenzene
766-85-8

3-methoxy-1-iodobenzene

2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

C14H9ClFNO

C14H9ClFNO

Conditions
ConditionsYield
Stage #1: 2-chloro-6-fluorobenzonitrile With lithium chlorozincate; lithium dicyclohexylamide In tetrahydrofuran at 0℃; for 0.0111111h; Flow reactor;
Stage #2: 3-methoxy-1-iodobenzene With trifuran-2-yl-phosphane; bis(dibenzylideneacetone)-palladium(0) In tetrahydrofuran at 25℃; for 2h; Negishi Coupling; Flow reactor;
97%
2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

2-chloro-6-fluorobenzoic acid
434-75-3

2-chloro-6-fluorobenzoic acid

Conditions
ConditionsYield
With 1-butyl-3-methylimidazolium hydrogen sulfate; water at 60 - 65℃; for 2.5h; Green chemistry;95%
2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

methylhydrazine
60-34-4

methylhydrazine

4-chloro-1-methyl-1H-indazol-3-amine
959240-93-8

4-chloro-1-methyl-1H-indazol-3-amine

Conditions
ConditionsYield
In ethanol Reflux; regioselective reaction;94%
2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

guanidine hydrogen carbonate
124-46-9, 20734-13-8, 100224-74-6, 593-85-1

guanidine hydrogen carbonate

5-chloro-2,4-diaminoquinazoline
17511-21-6

5-chloro-2,4-diaminoquinazoline

Conditions
ConditionsYield
In N,N-dimethyl acetamide at 140 - 142℃; for 7h;92%
2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

2-chloro-6-hydrazinobenzonitrile

2-chloro-6-hydrazinobenzonitrile

Conditions
ConditionsYield
With hydrazine In tetrahydrofuran at 20 - 30℃; for 0.75h;90%
2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

S-tert-butylsulfinimide
146374-27-8

S-tert-butylsulfinimide

N-(2-cyano-3-fluorophenyl)-2-methylpropane-2-sulfinamide
1338209-85-0

N-(2-cyano-3-fluorophenyl)-2-methylpropane-2-sulfinamide

Conditions
ConditionsYield
With palladium diacetate; caesium carbonate; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene In 1,4-dioxane at 110℃; for 15h; Inert atmosphere;90%
2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

sodium methylate
124-41-4

sodium methylate

2-Chlor-6-methoxybenzoesaeurenitril
6575-10-6

2-Chlor-6-methoxybenzoesaeurenitril

Conditions
ConditionsYield
In methanol at 85℃;89.8%
2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

2-chloro-6-fluorobenzyl amine
15205-15-9

2-chloro-6-fluorobenzyl amine

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran; diethyl ether at 0℃; for 24h; Inert atmosphere;89%
With indium(III) chloride; sodium tetrahydroborate In tetrahydrofuran at 25℃; for 4h; Inert atmosphere;75%
With lithium borohydride In tetrahydrofuran at 25℃; for 3h;70%
With lithium borohydride; diisopropopylaminoborane In tetrahydrofuran for 2h; Reflux;70%
With diisobutylaluminum borohydride In tetrahydrofuran at 25℃; for 1h; Inert atmosphere;16%
2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

2-chloro-6-ethoxybenzonitrile

2-chloro-6-ethoxybenzonitrile

Conditions
ConditionsYield
In tetrahydrofuran; ethanol87%
In tetrahydrofuran; ethanol87%
ethanol
64-17-5

ethanol

2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

2-chloro-6-ethoxybenzonitrile

2-chloro-6-ethoxybenzonitrile

Conditions
ConditionsYield
Stage #1: ethanol With sodium t-butanolate In tetrahydrofuran at 20℃; for 0.166667h;
Stage #2: 2-chloro-6-fluorobenzonitrile In tetrahydrofuran at 20℃; for 0.5h;
87%
2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

2-chloro-6-mercapto-benzonitrile
72371-52-9

2-chloro-6-mercapto-benzonitrile

Conditions
ConditionsYield
Stage #1: 2-chloro-6-fluorobenzonitrile With sodium sulfide In N,N-dimethyl-formamide at 20℃; for 1h; Inert atmosphere;
Stage #2: With hydrogenchloride; zinc In water Cooling with ice; Inert atmosphere;
86%
Stage #1: 2-chloro-6-fluorobenzonitrile In dimethyl sulfoxide at 75℃; for 0.333333h;
Stage #2: With sodiumsulfide nonahydrate In dimethyl sulfoxide at 75℃; for 2h;
2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

para-methylphenylmagnesium bromide
4294-57-9

para-methylphenylmagnesium bromide

3-fluoro-4'-methylbiphenyl-2-carbonitrile
1239886-78-2

3-fluoro-4'-methylbiphenyl-2-carbonitrile

Conditions
ConditionsYield
With manganese(ll) chloride In tetrahydrofuran at 0℃; for 0.5h;83%
2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

2-chloro-6-(cyanomethyl)benzonitrile
1184843-24-0

2-chloro-6-(cyanomethyl)benzonitrile

Conditions
ConditionsYield
Stage #1: methyl 2-cyanoacetate With sodium hydride In dimethyl sulfoxide at 0 - 20℃; for 0.5h;
Stage #2: 2-chloro-6-fluorobenzonitrile In dimethyl sulfoxide at 90℃;
83%
2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

2-chloro-6-fluoro-benzamide
66073-54-9

2-chloro-6-fluoro-benzamide

Conditions
ConditionsYield
With sulfuric acid at 75℃; for 3.5h;80%
With sulfuric acid at 70℃; for 4h;80%
With dihydrogen peroxide; potassium carbonate In dimethyl sulfoxide at 0 - 25℃;
With sulfuric acid at 60 - 70℃;5.5 g
2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

6-chloro-2-fluoro-3-formylbenzonitrile

6-chloro-2-fluoro-3-formylbenzonitrile

Conditions
ConditionsYield
With lithium diisopropyl amide In tetrahydrofuran; hexane; cyclohexane at -40℃; Flow reactor;80%
Stage #1: 2-chloro-6-fluorobenzonitrile With lithium diisopropyl amide In tetrahydrofuran; n-heptane at -70℃; for 0.5h; Inert atmosphere;
Stage #2: N,N-dimethyl-formamide In tetrahydrofuran; n-heptane at -70℃; for 0.5h;
17%
2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

2-amino-phenol
95-55-6

2-amino-phenol

1-chlorodibenzo[b,f][1,4]oxazepin-11-amine

1-chlorodibenzo[b,f][1,4]oxazepin-11-amine

Conditions
ConditionsYield
With potassium phosphate In N,N-dimethyl-formamide at 100℃; for 6h;80%
2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

2-(2-fluorophenyl)-5,5-dimethyl-[1,3,2]dioxaborinane
346656-39-1

2-(2-fluorophenyl)-5,5-dimethyl-[1,3,2]dioxaborinane

2′-fluoro-3-fluorobiphenyl-2-carbonitrile
537036-82-1

2′-fluoro-3-fluorobiphenyl-2-carbonitrile

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In ethanol; toluene at 80℃; for 63h; Suzuki-Miyaura coupling;78%
2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

2-chloro-6-fluorobenzenecarbothioamide
769-05-1

2-chloro-6-fluorobenzenecarbothioamide

Conditions
ConditionsYield
With pyridine; diammonium sulfide; triethylamine at 50℃; for 4h;78%
With diammonium sulfide; triethylamine In pyridine at 50℃;75%
With pyridine; triethylamine In (2S)-N-methyl-1-phenylpropan-2-amine hydrate72%
2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

5,8-dihydro-5-phenyl-5,8-diazaindeno[2,1-c]fluorene

5,8-dihydro-5-phenyl-5,8-diazaindeno[2,1-c]fluorene

C31H18ClN3

C31H18ClN3

Conditions
ConditionsYield
Stage #1: 2-chloro-6-fluorobenzonitrile; 5,8-dihydro-5-phenyl-5,8-diazaindeno[2,1-c]fluorene With sodium t-butanolate In toluene for 0.5h; Reflux;
Stage #2: With tetrakis(triphenylphosphine) palladium(0) In toluene for 3h; Reflux;
78%
2,2,2-trifluoroethanol
75-89-8

2,2,2-trifluoroethanol

2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

3-chloro-6-2',2',2'-trifluoroethoxybenzonitrile
93624-59-0

3-chloro-6-2',2',2'-trifluoroethoxybenzonitrile

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 150℃; for 15h;77%
2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

sodium 2,2,2-trifluoroethanolate
420-87-1

sodium 2,2,2-trifluoroethanolate

3-chloro-6-2',2',2'-trifluoroethoxybenzonitrile
93624-59-0

3-chloro-6-2',2',2'-trifluoroethoxybenzonitrile

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 90℃;77%
2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

5,12-dihydro-5-phenyl indolo[3,2-a]carbazole
1247053-55-9

5,12-dihydro-5-phenyl indolo[3,2-a]carbazole

C31H18ClN3

C31H18ClN3

Conditions
ConditionsYield
Stage #1: 2-chloro-6-fluorobenzonitrile; 5,12-dihydro-5-phenyl indolo[3,2-a]carbazole With sodium t-butanolate In toluene for 0.5h; Reflux;
Stage #2: With tetrakis(triphenylphosphine) palladium(0) In toluene for 3h; Reflux;
77%
Trimethyl borate
121-43-7

Trimethyl borate

2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

(4-chloro-3-cyano-2-fluorophenyl)boronic acid

(4-chloro-3-cyano-2-fluorophenyl)boronic acid

Conditions
ConditionsYield
With lithium diisopropyl amide In tetrahydrofuran; hexane; cyclohexane at -40℃; Flow reactor;76%
carbon dioxide
124-38-9

carbon dioxide

2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

4-chloro-3-cyano-2-fluorobenzoic acid

4-chloro-3-cyano-2-fluorobenzoic acid

Conditions
ConditionsYield
With lithium diisopropyl amide In tetrahydrofuran; hexane; cyclohexane at -50℃; Flow reactor;76%
Stage #1: 2-chloro-6-fluorobenzonitrile With lithium diisopropyl amide In tetrahydrofuran at -65℃; for 0.25h; Inert atmosphere;
Stage #2: carbon dioxide In tetrahydrofuran at -50 - 20℃; for 1.75h;
42%
9-phenyl-3,3'-bicarbazole
1060735-14-9

9-phenyl-3,3'-bicarbazole

2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

C37H22ClN3

C37H22ClN3

Conditions
ConditionsYield
Stage #1: 9-phenyl-3,3'-bicarbazole; 2-chloro-6-fluorobenzonitrile With sodium t-butanolate In toluene for 0.5h; Reflux;
Stage #2: With tetrakis(triphenylphosphine) palladium(0) In toluene for 3h; Reflux;
75%
2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
61676-62-8

2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

2-chloro-6-fluorobenzonitrile
668-45-1

2-chloro-6-fluorobenzonitrile

6-chloro-2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile

6-chloro-2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile

Conditions
ConditionsYield
With lithium diisopropyl amide In tetrahydrofuran; hexane; cyclohexane at -40℃; Flow reactor;73%

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