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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Large Stock 99.0% 4-Piperidinone, 1,2,5-trimethyl- 7516-33-8 Producer

Cas:7516-33-8

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Manufacturer supply CAS 7516-33-8 with competitive price

Cas:7516-33-8

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

4-Piperidinone, 1,2,5-trimethyl-

Cas:7516-33-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

4-PIPERIDINONE, 1,2,5-TRIMETHYL-

Cas:7516-33-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

4-Piperidinone, 1,2,5-trimethyl-

Cas:7516-33-8

Min.Order:0

Negotiable

Type:Trading Company

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TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

4-Piperidinone, 1,2,5-trimethyl-

Cas:7516-33-8

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

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Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

4-Piperidinone, 1,2,5-trimethyl-

Cas:7516-33-8

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

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Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

4-Piperidinone, 1,2,5-trimethyl-

Cas:7516-33-8

Min.Order:0

Negotiable

Type:Other

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Antimex Chemical Limied

Our own factory produces direct sales with absolute price advantage Application:Pharmaceutical industry Transportation:By sea Port:Shanghai/tianjin

4-Piperidinone, 1,2,5-trimethyl-

Cas:7516-33-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SAGECHEM LIMITED

laboratory Application:Synthetic building block

4-Piperidinone, 1,2,5-trimethyl-

Cas:7516-33-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

Our own factory produces direct sales with absolute price advantage Application:Pharmaceutical industry Transportation:By sea Port:Shanghai/tianjin

4-Piperidinone, 1,2,5-trimethyl-

Cas:7516-33-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemsigma International Co.,Ltd.

bulk production Chemsigma International Co.,Ltd. is a chemical manufacturer, specialize in custom synthesis and organic chemical manufacturing for overseas customers, in the field of API, pharmaceutical intermediates, chemical intermediates, fine ch

4-Piperidinone, 1,2,5-triMethyl-

Cas:7516-33-8

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

4-Piperidinone, 1,2,5-trimethyl-

Cas:7516-33-8

Min.Order:0

Negotiable

Type:Trading Company

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Shanghai united Scientific Co.,Ltd.

United Scientific Company Located in Shanghai of China , is a competitive player in the global specialty and fine chemical market. Fenghua has both the expertise and flexibility to produce a wide range of chemicals. Focusing on developing the innovat

4-Piperidinone, 1,2,5-trimethyl-

Cas:7516-33-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemical Technology Co.,LTD

1. Production capacity: we have three production base with high-tech production equipment and instruments, equipped with professional production personnel, meet your requirements.2. Quality assurance: we have a first-class testing equipment and testi

4-Piperidinone, 1,2,5-triMethyl-

Cas:7516-33-8

Min.Order:0

Negotiable

Type:Other

inquiry

Shaanxi Mingqi Chemical Co., Ltd

Known for its best quality and competitve price, this chemicals we offered is widely appreciated by our customers. Our advantages:1, High quality with competitive price:1) Standard:BP/USP/EP/Enterprise standard2) All Purity≥99%3) We are manufacturer

4-Piperidinone, 1,2,5-trimethyl-

Cas:7516-33-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

GZ HONESTCHEM CO., LTD

4-Piperidinone, 1,2,5-trimethyl-Appearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air

4-Piperidinone, 1,2,5-trimethyl-

Cas:7516-33-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

ENAO Chemical Co, Limited

kodgyq8oAppearance:white powders Storage:Store at 2-8°C. Package:As per buyer requirement Application:Pharmaceuticals, Skincare, Medical Ingedients and others Transportation:By courier or By sea Port:As per buyer requirement

1,2,5-Trimethylpiperidin-4-one

Cas:7516-33-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

5-methoxy-2-methyl-1-hexen-3-one
13058-36-1

5-methoxy-2-methyl-1-hexen-3-one

methylamine
74-89-5

methylamine

1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

Conditions
ConditionsYield
In methanol; water at 60℃; for 4h;71.2%
3-[(2-methoxycarbonyl-propyl)-methyl-amino]-butyric acid ethyl ester
897400-05-4

3-[(2-methoxycarbonyl-propyl)-methyl-amino]-butyric acid ethyl ester

1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

Conditions
ConditionsYield
Stage #1: 3-[(2-methoxycarbonyl-propyl)-methyl-amino]-butyric acid ethyl ester With ethanol; sodium In xylenes at 20 - 75℃; for 8h; Heating / reflux;
Stage #2: With hydrogenchloride In water for 6h; Heating / reflux;
Stage #3: With potassium hydroxide In water at 0℃; pH=10;
47%
N-(1,2,5-trimethylpiperidylidene-4)aniline
60585-74-2, 127611-57-8, 127611-58-9, 127611-59-0

N-(1,2,5-trimethylpiperidylidene-4)aniline

benzylmagnesium chloride
6921-34-2

benzylmagnesium chloride

A

1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

B

1-methyl-2r,5c-dimethyl-4t-benzyl-4c-phenylaminopiperidine
129115-34-0

1-methyl-2r,5c-dimethyl-4t-benzyl-4c-phenylaminopiperidine

C

aniline
62-53-3

aniline

Conditions
ConditionsYield
In diethyl ether for 8h; Heating;A n/a
B 46%
C n/a
5-ethoxy-2-methyl-1-hexen-3-one
103263-54-3

5-ethoxy-2-methyl-1-hexen-3-one

methylamine
74-89-5

methylamine

1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

Conditions
ConditionsYield
In methanol; water at 60℃; for 4h;45.5%
phenyllithium
591-51-5

phenyllithium

N-(1,2,5-trimethylpiperidinylidene-4-)-β-hydroxyethylamine
113556-34-6

N-(1,2,5-trimethylpiperidinylidene-4-)-β-hydroxyethylamine

A

1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

B

ethanolamine
141-43-5

ethanolamine

C

1,2,5-trimethyl-4-phenyl-4-N-(β-hydroxyethyl)aminopiperidine
113556-41-5

1,2,5-trimethyl-4-phenyl-4-N-(β-hydroxyethyl)aminopiperidine

Conditions
ConditionsYield
In diethyl etherA n/a
B n/a
C 11%
2,5-dimethyl-tetrahydro-pyran-4-one
66109-81-7

2,5-dimethyl-tetrahydro-pyran-4-one

methylamine
74-89-5

methylamine

1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

Conditions
ConditionsYield
With water
2,5-dimethylpiperidin-4-one
4558-87-6

2,5-dimethylpiperidin-4-one

methyl iodide
74-88-4

methyl iodide

1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

Conditions
ConditionsYield
With 1,4-dioxane
2-methyl-hexa-1,5-dien-3-yne
820-54-2

2-methyl-hexa-1,5-dien-3-yne

1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

Conditions
ConditionsYield
With water; butan-1-ol Erwaermen unter Zusatz von Schwefelsaeure und Quecksilber(II)-sulfat und Erwaermen des Reaktionsgemisches mit wss. Methylamin in Aethanol;
(E)-2-methylhexa-1,4-dien-3-one
13058-39-4, 105645-96-3, 105645-99-6

(E)-2-methylhexa-1,4-dien-3-one

methylamine
74-89-5

methylamine

1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

Conditions
ConditionsYield
With water
1,5-dimethoxy-2-methyl-hexan-3-one
41854-15-3

1,5-dimethoxy-2-methyl-hexan-3-one

methylamine
74-89-5

methylamine

1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

Conditions
ConditionsYield
With water
2,5-dimethyl-tetrahydro-pyran-4-one
66109-81-7

2,5-dimethyl-tetrahydro-pyran-4-one

water
7732-18-5

water

methylamine
74-89-5

methylamine

1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

3-Methyl-3-buten-2-one
814-78-8

3-Methyl-3-buten-2-one

1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 82.3 percent / NaI, Et3N / acetonitrile / 1 h / 70 °C
2: 60.6 percent / ZnCl2 / ethyl acetate / 1 h / 40 °C
3: 45.5 percent / methanol; H2O / 4 h / 60 °C
View Scheme
Multi-step reaction with 3 steps
1: 82.3 percent / NaI, Et3N / acetonitrile / 1 h / 70 °C
2: 68.2 percent / ZnCl2 / ethyl acetate / 1 h / 40 °C
3: 71.2 percent / methanol; H2O / 4 h / 60 °C
View Scheme
2-methyl-3-<(trimethylsilyl)oxy>-1,3-butadiene
54781-31-6

2-methyl-3-<(trimethylsilyl)oxy>-1,3-butadiene

1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 60.6 percent / ZnCl2 / ethyl acetate / 1 h / 40 °C
2: 45.5 percent / methanol; H2O / 4 h / 60 °C
View Scheme
Multi-step reaction with 2 steps
1: 68.2 percent / ZnCl2 / ethyl acetate / 1 h / 40 °C
2: 71.2 percent / methanol; H2O / 4 h / 60 °C
View Scheme
C13H25NO4
1252678-29-7

C13H25NO4

1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

Conditions
ConditionsYield
Stage #1: C13H25NO4 With sodium In 5,5-dimethyl-1,3-cyclohexadiene; ethanol Dieckmann reaction; Reflux;
Stage #2: With hydrogenchloride In water Reflux;
1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

3-methyl-2-pyrazoline-5-one
108-26-9

3-methyl-2-pyrazoline-5-one

malononitrile
109-77-3

malononitrile

C15H21N5O

C15H21N5O

Conditions
ConditionsYield
In ethanol at 20℃; for 12h;94%
1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

acetic acid hydrazide
1068-57-1

acetic acid hydrazide

1,2,5-Trimethyl-4-piperidone acetylhydrazone
102689-09-8

1,2,5-Trimethyl-4-piperidone acetylhydrazone

Conditions
ConditionsYield
at 20℃; for 0.25h;90%
1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

2-aminoethyl vinyl ether
7336-29-0

2-aminoethyl vinyl ether

1,2,5-trimethyl-4-(β-vinyloxyethylimino)piperidine
72310-54-4

1,2,5-trimethyl-4-(β-vinyloxyethylimino)piperidine

Conditions
ConditionsYield
In benzene Heating;85%
1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

(S)-1-phenyl-ethylamine
2627-86-3

(S)-1-phenyl-ethylamine

(-)-1,2,5-trimethyl-4-(1S-phenylethylimino)piperidine

(-)-1,2,5-trimethyl-4-(1S-phenylethylimino)piperidine

Conditions
ConditionsYield
With toluene-4-sulfonic acid In benzene Heating;85%
1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

1,2,5-trimethylpiperidine-4-one oxime
113849-83-5, 131485-23-9

1,2,5-trimethylpiperidine-4-one oxime

Conditions
ConditionsYield
With hydroxylamine hydrochloride; sodium acetate In ethanol for 4h; Heating;81%
1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

acetonitrile
75-05-8

acetonitrile

N-(4-Acetylamino-1,2,5-trimethyl-piperidin-4-yl)-acetamide

N-(4-Acetylamino-1,2,5-trimethyl-piperidin-4-yl)-acetamide

Conditions
ConditionsYield
With sulfuric acid at 60℃; for 2h;81%
1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

benzylamine
100-46-9

benzylamine

N-(1-methyl-2,5-dimethyl-4-piperidylidene)benzylamine
113556-33-5

N-(1-methyl-2,5-dimethyl-4-piperidylidene)benzylamine

Conditions
ConditionsYield
With zinc(II) chloride In toluene Heating; catalytic amount of acetic acid, benzene;76.5%
In toluene Heating;
1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

aniline
62-53-3

aniline

N-(1,2,5-trimethylpiperidylidene-4)aniline
60585-74-2, 127611-57-8, 127611-58-9, 127611-59-0

N-(1,2,5-trimethylpiperidylidene-4)aniline

Conditions
ConditionsYield
With acetic acid In toluene Heating;72%
With toluene-4-sulfonic acid In benzene Heating;71.3%
1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

propan-1-ol-3-amine
156-87-6

propan-1-ol-3-amine

N-(1,2,5-trimethylpiperidylidene-4-)-γ-hydroxypropylamine
113556-47-1

N-(1,2,5-trimethylpiperidylidene-4-)-γ-hydroxypropylamine

Conditions
ConditionsYield
With zinc(II) chloride In toluene Heating; catalytic amount of acetic acid, benzene;72%
1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

1,2,5-trimethyl-4-naphthalen-1-ylethynyl-piperidin-4-ol
40964-05-4

1,2,5-trimethyl-4-naphthalen-1-ylethynyl-piperidin-4-ol

Conditions
ConditionsYield
Stage #1: 1-ethynylnaphthalene With n-butyllithium In tetrahydrofuran; hexanes at 0 - 20℃; for 1.08333h;
Stage #2: 1,2,5-trimethyl-4-piperidone In tetrahydrofuran; hexanes at 20℃; for 1h;
67%
1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

diethyldiethynylsilane
18292-19-8

diethyldiethynylsilane

β-isomer of 4-<(diethylethynylsilyl)ethynyl>-1,2,5-trimethyl-4-piperidinol

β-isomer of 4-<(diethylethynylsilyl)ethynyl>-1,2,5-trimethyl-4-piperidinol

γ-isomer of 4-<(diethylethynylsilyl)ethynyl>-1,2,5-trimethyl-4-piperidinol

γ-isomer of 4-<(diethylethynylsilyl)ethynyl>-1,2,5-trimethyl-4-piperidinol

Conditions
ConditionsYield
With ethylmagnesium bromide In diethyl ether at 80 - 90℃; for 2h;A 17.55%
B 52.45%
1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

N-methyl-N-propargylaniline
4282-82-0

N-methyl-N-propargylaniline

1,2,5-trimethyl-4-hydroxy-4-<3-(N-methyl-N-phenylamino)-propynyl>piperidine

1,2,5-trimethyl-4-hydroxy-4-<3-(N-methyl-N-phenylamino)-propynyl>piperidine

1,2,5-trimethyl-4-hydroxy-4-<3-(N-methyl-N-phenylamino)-propynyl>piperidine

1,2,5-trimethyl-4-hydroxy-4-<3-(N-methyl-N-phenylamino)-propynyl>piperidine

1,2,5-trimethyl-4-hydroxy-4-<3-(N-methyl-N-phenylamino)-propynyl>piperidine

1,2,5-trimethyl-4-hydroxy-4-<3-(N-methyl-N-phenylamino)-propynyl>piperidine

Conditions
ConditionsYield
With potassium hydroxide In diethyl ether for 8h; Ambient temperature;A 8%
B 32%
C 51%
1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

aniline
62-53-3

aniline

1,2,5-trimethyl-4-N-phenyliminopiperidine
60585-74-2, 127611-57-8, 127611-58-9, 127611-59-0

1,2,5-trimethyl-4-N-phenyliminopiperidine

Conditions
ConditionsYield
With toluene-4-sulfonic acid In benzene Heating;50%
1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

1,2-diamino-benzene
95-54-5

1,2-diamino-benzene

A

C14H21N3
83821-86-7

C14H21N3

B

N-[1,2,5-Trimethyl-piperidin-(4Z)-ylidene]-benzene-1,2-diamine
83821-90-3

N-[1,2,5-Trimethyl-piperidin-(4Z)-ylidene]-benzene-1,2-diamine

Conditions
ConditionsYield
With toluene-4-sulfonic acid In benzene Heating;A 5%
B 50%
1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

rac-methylbenzylamine
618-36-0

rac-methylbenzylamine

N-(1-methyl-2,5-dimethyl-4-piperidylidene)-α-phenylethylamine
142917-25-7

N-(1-methyl-2,5-dimethyl-4-piperidylidene)-α-phenylethylamine

Conditions
ConditionsYield
In toluene Heating;49%
1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

m,p-dichloroaniline
95-76-1

m,p-dichloroaniline

N-(1,2,5-trimethyl-4-piperidylidene)-3,4-dichloroaniline
136038-82-9

N-(1,2,5-trimethyl-4-piperidylidene)-3,4-dichloroaniline

Conditions
ConditionsYield
With acetic acid In toluene for 8h; Heating;40%
1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

4-p-dimethylaminophenyl-3-buten-2-one
5432-53-1

4-p-dimethylaminophenyl-3-buten-2-one

4a-hydroxy-8-(p-dimethylaminophenyl)-2,3,8a-trimethyldecahydro-6-isoquinolone

4a-hydroxy-8-(p-dimethylaminophenyl)-2,3,8a-trimethyldecahydro-6-isoquinolone

Conditions
ConditionsYield
Stage #1: 1,2,5-trimethyl-4-piperidone With sodium hydride In water; N,N-dimethyl-formamide at 20℃; Mannich reaction;
Stage #2: 4-p-dimethylaminophenyl-3-buten-2-one In water; N,N-dimethyl-formamide at 20℃; Mannich reaction;
40%
1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

ethanolamine
141-43-5

ethanolamine

N-(1,2,5-trimethylpiperidinylidene-4-)-β-hydroxyethylamine
113556-34-6

N-(1,2,5-trimethylpiperidinylidene-4-)-β-hydroxyethylamine

Conditions
ConditionsYield
With zinc(II) chloride In toluene Heating; catalytic amount of acetic acid, benzene;35%
1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

1-Phenylbut-1-en-3-one
122-57-6

1-Phenylbut-1-en-3-one

4a-hydroxy-2,3,8a-trimethyl-8-phenyldecahydro-6-isoquinolone

4a-hydroxy-2,3,8a-trimethyl-8-phenyldecahydro-6-isoquinolone

Conditions
ConditionsYield
Stage #1: 1,2,5-trimethyl-4-piperidone With sodium hydride In water; N,N-dimethyl-formamide at 20℃; for 1h; Mannich reaction;
Stage #2: 1-Phenylbut-1-en-3-one In water; N,N-dimethyl-formamide at 20℃; for 72h; Mannich reaction;
34%
1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

2,2,6,6-Tetramethyl-4-piperidone
826-36-8

2,2,6,6-Tetramethyl-4-piperidone

C20H30N2S

C20H30N2S

Conditions
ConditionsYield
With sulfuric acid at 60 - 65℃; for 4h;32%
1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

ortho-cresol
95-48-7

ortho-cresol

trans-1,2,5-Trimethyl-4-(4-hydroxy-3-methylphenyl)-Δ3-tetrahydropyridine
108332-84-9

trans-1,2,5-Trimethyl-4-(4-hydroxy-3-methylphenyl)-Δ3-tetrahydropyridine

Conditions
ConditionsYield
With boron trifluoride diethyl etherate31%
2-thiazolylamine
96-50-4

2-thiazolylamine

1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

1,2,5-trimethyl-4-(2-thiazolyl)iminopiperidine
139117-78-5

1,2,5-trimethyl-4-(2-thiazolyl)iminopiperidine

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene Heating;30%
1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

1,3-diphenyl-propen-3-one
614-47-1

1,3-diphenyl-propen-3-one

1,2,5-trimethyl-3-(3-oxo-1,3-diphenylpropyl)piperidin-4-one

1,2,5-trimethyl-3-(3-oxo-1,3-diphenylpropyl)piperidin-4-one

B

6-hydroxy-1,3,4-trimethyl-6,8-diphenyl-3-azabicyclo[3.3.1]nonan-9-one hydrochloride

6-hydroxy-1,3,4-trimethyl-6,8-diphenyl-3-azabicyclo[3.3.1]nonan-9-one hydrochloride

Conditions
ConditionsYield
With potassium hydroxide In ethanol; water for 5h; Michael reaction;A 6.39%
B 23.2%
1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

4-(2-methoxy-naphthalen-1-ylethynyl)-1,2,5-trimethyl-piperidin-4-ol

4-(2-methoxy-naphthalen-1-ylethynyl)-1,2,5-trimethyl-piperidin-4-ol

Conditions
ConditionsYield
Stage #1: 1-(2',2'-dibromovinyl)-2-methoxynaphthalene With n-butyllithium In tetrahydrofuran; hexanes at -78 - 20℃; for 1.5h;
Stage #2: 1,2,5-trimethyl-4-piperidone In tetrahydrofuran; hexanes at 20℃; for 0.25h;
19%
1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

carbon disulfide
75-15-0

carbon disulfide

sodium cyanide
143-33-9

sodium cyanide

1,2,5-trimethylpiperidine-4-spiro-5'-imidazolidine-2',4'-dithione

1,2,5-trimethylpiperidine-4-spiro-5'-imidazolidine-2',4'-dithione

Conditions
ConditionsYield
With ammonium chloride In ethanol at 50 - 55℃; for 24h;18%
1,2,5-trimethyl-4-piperidone
7516-33-8

1,2,5-trimethyl-4-piperidone

(2E)-3-(4-bromophenyl)-1-phenylprop-2-en-1-one
22966-09-2

(2E)-3-(4-bromophenyl)-1-phenylprop-2-en-1-one

8-(4-bromophenyl)-6-hydroxy-1,3,4-trimethyl-6-phenyl-3-azabicyclo[3.3.1]nonan-9-one hydrochloride

8-(4-bromophenyl)-6-hydroxy-1,3,4-trimethyl-6-phenyl-3-azabicyclo[3.3.1]nonan-9-one hydrochloride

Conditions
ConditionsYield
With potassium hydroxide In ethanol; water; benzene for 48h; Michael reaction;14.6%

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