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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

2-Butene-1,4-diol,(2E)- Manufacturer/High quality/Best price/In stock

Cas:821-11-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

(E)-2-Butene-1,4-diol

Cas:821-11-4

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

821-11-4 2-BUTENE-1,4-DIOL Now we would like to update our product list for you, kindly check the below information: 1. Catalyst series ( such as Noble Metal Catalyst, Phosphorous ligand, etc ) 2. Pharmaceutical Intermediate ( suc

821-11-4 2-BUTENE-1,4-DIOL

Cas:821-11-4

Min.Order:1 Metric Ton

FOB Price: $0.1 / 1.0

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 821-11-4 with competitive price

Cas:821-11-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2-Butene-1,4-diol,(2E)- 821-11-4

Cas:821-11-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:821-11-4

Cas:821-11-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

trans-2-Butene-1,4-diol

Cas:821-11-4

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

(2E)-But-2-ene-1,4-diol

Cas:821-11-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

trans-2-Butene-1,4-diol

Cas:821-11-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

(E)-but-2-ene-1,4-diol

Cas:821-11-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec trans-2-Butene-1,4-diol 25g

Cas:821-11-4

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

trans-2-Butene-1,4-diol

Cas:821-11-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

trans-2-Butene-1,4-diol

Cas:821-11-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Best quality with low price Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Shanghai

trans-2-Butene-1,4-diol

Cas:821-11-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Fandachem Co.,Ltd

2-Butene-1,4-diol,(2E)- cas 821-11-4Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

2-Butene-1,4-diol,(2E)- cas 821-11-4

Cas:821-11-4

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

2-Butene-1,4-diol

Cas:821-11-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Application:Medical or chemical

821-11-4

Cas:821-11-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai Scochem Technology Co., Ltd.

High quality suppliers Application:healing drugs

2-butene-1,4-diol

Cas:821-11-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemsigma International Co.,Ltd.

bulk?production Application:Pharmaceutical intermediates

2-Butene-1,4-diol

Cas:821-11-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

(E)-but-2-ene-1,4-diol

Cas:821-11-4

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Run-Biotech Co., Ltd.

Shanghai, Run-Biotech Co., Ltd is a leading domestic pharmaceutical, biopharmaceutical, and health care products R & D outsourcing services company. As an innovation-driven and customer-focused company, Run Biotech provides a broad and integrat

2-BUTENE-1,4-DIOL

Cas:821-11-4

Min.Order:1 Gram

FOB Price: $1.0

Type:Trading Company

inquiry

Wuhan Sun-shine Bio-technology Corporation Limited

Wuhan Sun-shine Bio-technology Corporation Limited is specializing in the anticancer, antitumor,heart head blood-vessel,pharmaceutical intermediates,fine Chemicals production and customization..Company has strong ability of research and development,

2-BUTENE-1,4-DIOL

Cas:821-11-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

U-Chemo Holding Co.,Limited

U-CHEMO is a high-tech enterprise taking pharmaceutical intermediates and fine chemicals as main products. We pay high attention on product quality and apply quality management in the whole manufacturing process from research to production. In additi

trans-2-Butene-1,4-diol

Cas:821-11-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

GZ HONESTCHEM CO., LTD

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

(E)-but-2-ene-1,4-diol

Cas:821-11-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

YangZhou ZhiDa Chemical Co.,Ltd.

CAS Number: 821-11-4 Linear Formula: C4H8O2 Molecular Weight: 88.11 Appearance slightly pale yellow clear oil Assay(GC) Min. 97% m.p 25°C IR,…Appearance:slightly pale yellow clear oila Package:1g/5g/25g

2-Butene-1,4-diol,(2E)-

Cas:821-11-4

Min.Order:0 Gram

FOB Price: $700.0 / 750.0

Type:Other

inquiry

Finetech Industry Limited

High Quality Best Price Storage:Store in dry, dark and ventilated place Application:Chemical Synthesis Intermediate

FT-0701262

Cas:821-11-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

1,4-dihydroxybut-2-yne
110-65-6

1,4-dihydroxybut-2-yne

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 20℃; for 48h; Inert atmosphere;100%
With lithium aluminium tetrahydride In tetrahydrofuran for 3h; Reduction; Heating;99%
With lithium aluminium tetrahydride In tetrahydrofuran for 18h; Heating;90%
(E)-2-Hexen-1-ol
928-95-0

(E)-2-Hexen-1-ol

A

trans-4-Octene
14850-23-8

trans-4-Octene

B

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

Conditions
ConditionsYield
With C37H40Cl2N2ORuS2 In tetrahydrofuran-d8 at 45℃; for 1h; Inert atmosphere;A 100%
B 100%
allyl alcohol
107-18-6

allyl alcohol

(R)-3-allylsulfanyl-2-tert-butoxycarbonylaminopropionic acid methyl ester
232953-12-7

(R)-3-allylsulfanyl-2-tert-butoxycarbonylaminopropionic acid methyl ester

A

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

B

C13H23NO5S
1043521-67-0

C13H23NO5S

Conditions
ConditionsYield
With Hoveyda-Grubbs catalyst second generation In water; tert-butyl alcohol at 32℃; for 2.5h; optical yield given as %de;A 99%
B 56%
trans-1,4-diacetoxy-2-butene
1576-98-3

trans-1,4-diacetoxy-2-butene

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

Conditions
ConditionsYield
With hydrogenchloride; diethyl ether; water In ethanol for 16h; Inert atmosphere; Reflux;98%
With hydrogenchloride In ethanol; water at 80℃; for 12h;72%
Trifluoro-acetic acid (E)-4-(2,2,2-trifluoro-acetoxy)-but-2-enyl ester

Trifluoro-acetic acid (E)-4-(2,2,2-trifluoro-acetoxy)-but-2-enyl ester

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

Conditions
ConditionsYield
With silica gel; triethylamine In diethyl ether; Petroleum ether Substitution; Detrifluoroacetylation;95%
(E)-1,4-bis(2-tetrahydropyranyloxy)-2-butene

(E)-1,4-bis(2-tetrahydropyranyloxy)-2-butene

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

Conditions
ConditionsYield
With tetra-N-butylammonium tribromide In methanol at 20℃; for 0.16h;95%
diethyl Fumarate
623-91-6

diethyl Fumarate

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

Conditions
ConditionsYield
With diisobutylaluminium hydride In toluene at 20℃; for 12h;79%
With diisobutylaluminium hydride In toluene at 20℃; Inert atmosphere;60%
With diethylaluminium hydride; benzene
With diisobutylaluminium hydride; benzene
With diisobutylaluminium hydride In hexane; benzene at 5 - 20℃; for 3h;
butyne-1,4-diol
628-23-9

butyne-1,4-diol

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 20℃; for 12.3333h; Inert atmosphere;67%
With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 20℃; for 12h;67%
allyl alcohol
107-18-6

allyl alcohol

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

Conditions
ConditionsYield
With Hoveyda-Grubbs catalyst second generation; 5,17-bis[(3-(2,6-diisopropylphenyl)imidazolium)methyl]-25,26,27,28-tetrapropoxycalix[4]arene dichloride In water at 45℃; for 24h; optical yield given as %de;54%
methylene-pyridinium-tagged Hoveyda-Grubbs pre-catalyst at 25℃; for 3.5h;99 % Chromat.
epoxybutene
930-22-3

epoxybutene

A

3,4-butenediol
497-06-3

3,4-butenediol

B

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

Conditions
ConditionsYield
With water
trans-1,4-dichlorobut-2-ene
110-57-6

trans-1,4-dichlorobut-2-ene

A

3,4-butenediol
497-06-3

3,4-butenediol

B

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

Conditions
ConditionsYield
With sodium carbonate
With sodium carbonate at 90 - 95℃;
(E)-1,4-dibromobutene
821-06-7

(E)-1,4-dibromobutene

A

3,4-butenediol
497-06-3

3,4-butenediol

B

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

Conditions
ConditionsYield
With sodium carbonate at 90 - 95℃;
(E)-1,4-dibromobutene
821-06-7

(E)-1,4-dibromobutene

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

Conditions
ConditionsYield
With water; lead(II) oxide
With lead(II) oxide In water Heating;
(2E)-but-2-enedioic acid
110-17-8

(2E)-but-2-enedioic acid

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

Conditions
ConditionsYield
With lithium aluminium tetrahydride; diethyl ether
Acetylenedicarboxylic acid
142-45-0

Acetylenedicarboxylic acid

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

Conditions
ConditionsYield
With lithium aluminium tetrahydride; diethyl ether
buta-1,3-diene
106-99-0

buta-1,3-diene

A

3,4-butenediol
497-06-3

3,4-butenediol

B

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

Conditions
ConditionsYield
With sodium perchlorate In water; acetonitrile (electrolysis);
1,4-dihydroxybut-2-yne
110-65-6

1,4-dihydroxybut-2-yne

A

1,4-butenediol
6117-80-2

1,4-butenediol

B

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

Conditions
ConditionsYield
With hydrogen; ruthenium palladium In propan-1-ol at 89.9℃; Rate constant;
With hydrogen; copper(II) sulfate; nickel In ammonium hydroxide; water at 40℃; under 5250.4 Torr; Title compound not separated from byproducts;
With hydrogen In isopropyl alcohol at 30℃; under 7500.75 Torr; for 1h; Autoclave; optical yield given as %de; stereoselective reaction;
(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

Formic acid (2S,3S)-4-formyloxy-2,3-dihydroxy-butyl ester

Formic acid (2S,3S)-4-formyloxy-2,3-dihydroxy-butyl ester

A

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

B

(R)-(+)-3,4-dihydroxy-1-butene
86106-09-4

(R)-(+)-3,4-dihydroxy-1-butene

Conditions
ConditionsYield
With sodium methylate In methanol Ambient temperature; Yield given;
dimethylfumarate
624-49-7

dimethylfumarate

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

Conditions
ConditionsYield
With diisobutylaluminium hydride In toluene 1.) -78 deg C, 90 min, 2.) 0 deg C, 30 min;
With diisobutylaluminium hydride In toluene at -10 - 20℃; for 18h;
With diisobutylaluminium hydride In toluene at -10 - 20℃; for 18h;
dl-2,3-dibromo-1,4-butanediol
1947-58-6

dl-2,3-dibromo-1,4-butanediol

A

1,4-butenediol
6117-80-2

1,4-butenediol

B

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

Conditions
ConditionsYield
With samarium In methanol for 1h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
epoxybutene
930-22-3

epoxybutene

A

2,5-dihydrofuran
1708-29-8

2,5-dihydrofuran

B

trans-Crotonaldehyde
123-73-9

trans-Crotonaldehyde

C

3,4-butenediol
497-06-3

3,4-butenediol

D

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

E

4-iodo-2-butene-1-ol

4-iodo-2-butene-1-ol

Conditions
ConditionsYield
With potassium iodide; USY zeolite In various solvent(s) at 74.85℃; for 24h; Product distribution; Mechanism; var. nucleophiles and acids; var. solv. and time;
diethyl ether
60-29-7

diethyl ether

(2E)-but-2-enedioic acid
110-17-8

(2E)-but-2-enedioic acid

lithium alanate

lithium alanate

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

diethyl ether
60-29-7

diethyl ether

Acetylenedicarboxylic acid
142-45-0

Acetylenedicarboxylic acid

lithium alanate

lithium alanate

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

1,4-dihydroxybut-2-yne
110-65-6

1,4-dihydroxybut-2-yne

palladium/charcoal

palladium/charcoal

ethanolic NaOH-solution

ethanolic NaOH-solution

A

1,4-butenediol
6117-80-2

1,4-butenediol

B

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

Conditions
ConditionsYield
Hydrogenation;
1,4-dihydroxybut-2-yne
110-65-6

1,4-dihydroxybut-2-yne

ethanol
64-17-5

ethanol

Raney nickel

Raney nickel

A

2,5-dihydrofuran
1708-29-8

2,5-dihydrofuran

B

Butane-1,4-diol
110-63-4

Butane-1,4-diol

C

1,4-butenediol
6117-80-2

1,4-butenediol

D

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

Conditions
ConditionsYield
Produkt5: But-2ξ-en-1-ol.Hydrogenation;
diacetate of trans-butene-(2)-diol-(1.4)

diacetate of trans-butene-(2)-diol-(1.4)

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

Conditions
ConditionsYield
With barium dihydroxide
trans-1,4-dichlorobut-2-ene
110-57-6

trans-1,4-dichlorobut-2-ene

aqueous natrium carbonate

aqueous natrium carbonate

A

3,4-butenediol
497-06-3

3,4-butenediol

B

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

1-chloro-2-hydroxy-3-butene
671-56-7

1-chloro-2-hydroxy-3-butene

NaHCO3

NaHCO3

A

epoxybutene
930-22-3

epoxybutene

B

3,4-butenediol
497-06-3

3,4-butenediol

C

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

p-toluenesulfonyl chloride
98-59-9

p-toluenesulfonyl chloride

(E)-1,4-ditosyloxybut-2-ene
49837-05-0

(E)-1,4-ditosyloxybut-2-ene

Conditions
ConditionsYield
With sodium t-butanolate In tetrahydrofuran at 0 - 20℃;100%
With sodium t-butanolate In tetrahydrofuran at 0 - 20℃; Inert atmosphere;82%
With potassium hydroxide; N-benzyl-N,N,N-triethylammonium chloride In 1,4-dioxane at -3 - 20℃; for 3.5h;
With sodium t-butanolate
(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

acetic anhydride
108-24-7

acetic anhydride

trans-1-hydroxy-4-acetoxy-2-butene
27977-16-8, 64196-68-5, 70940-89-5

trans-1-hydroxy-4-acetoxy-2-butene

Conditions
ConditionsYield
With pyridine at 20℃; for 24h;95%
With sodium hydride In tetrahydrofuran Ambient temperature;70%
Stage #1: trans-butene-1,4-diol With pyridine In toluene for 0.166667h;
Stage #2: acetic anhydride In toluene at 0 - 20℃; for 24h;
45%
In pyridine
3,4-dihydro-2H-pyran
110-87-2

3,4-dihydro-2H-pyran

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

(E)-1,4-bis(2-tetrahydropyranyloxy)-2-butene

(E)-1,4-bis(2-tetrahydropyranyloxy)-2-butene

Conditions
ConditionsYield
With tetra-N-butylammonium tribromide In dichloromethane at 20℃; for 0.5h;95%
(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

benzyl bromide
100-39-0

benzyl bromide

(E)-1,4-bis(benzyloxy)-2-butene
68972-93-0

(E)-1,4-bis(benzyloxy)-2-butene

Conditions
ConditionsYield
Stage #1: trans-butene-1,4-diol With sodium hydride In tetrahydrofuran at 0℃; for 3.5h; Inert atmosphere; Reflux;
Stage #2: benzyl bromide In tetrahydrofuran for 3.5h; Inert atmosphere; Reflux;
93%
Stage #1: trans-butene-1,4-diol With sodium hydride In tetrahydrofuran; mineral oil at 0℃; Inert atmosphere; Reflux;
Stage #2: benzyl bromide In tetrahydrofuran for 3.5h; Inert atmosphere; Reflux;
91%
(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

4-biphenyl-carboxylic acid chloride
14002-51-8

4-biphenyl-carboxylic acid chloride

Biphenyl-4-carboxylic acid (E)-4-hydroxy-but-2-enyl ester

Biphenyl-4-carboxylic acid (E)-4-hydroxy-but-2-enyl ester

Conditions
ConditionsYield
With pyridine at 20℃; for 72h;92%
C-(N-tert-butoxycarbonylamino)methanol
365572-48-1

C-(N-tert-butoxycarbonylamino)methanol

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

C10H17NO3

C10H17NO3

Conditions
ConditionsYield
With cyclopentadienylruthenium(II) trisacetonitrile hexafluorophosphate In N,N-dimethyl acetamide at 100℃; Schlenk technique; Inert atmosphere; enantioselective reaction;92%
(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

trichloroacetonitrile
545-06-2

trichloroacetonitrile

C8H8Cl6N2O2
1256294-08-2

C8H8Cl6N2O2

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In tetrahydrofuran at -5℃; for 1h; Molecular sieve;91%
(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

ethyl (triphenylphosphoranylidene)acetate
1099-45-2

ethyl (triphenylphosphoranylidene)acetate

diethyl octa-2(E),4(E),6(E)-triene-1,8-dioate
5941-43-5

diethyl octa-2(E),4(E),6(E)-triene-1,8-dioate

Conditions
ConditionsYield
With 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione In dimethyl sulfoxide at 20℃; for 10h;90%
With Dess-Martin periodane; benzoic acid In dichloromethane; dimethyl sulfoxide at 20℃; for 0.5h;64%
methanol
67-56-1

methanol

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

1,4-dihydroxy-3-iodo-2-methoxybutane

1,4-dihydroxy-3-iodo-2-methoxybutane

Conditions
ConditionsYield
With dihydrogen peroxide; iodine at 20℃; for 12h;90%
(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

(E)-4-[(tert-butyldimethylsilyl)oxy]-2-buten-1-ol
91202-69-6

(E)-4-[(tert-butyldimethylsilyl)oxy]-2-buten-1-ol

Conditions
ConditionsYield
Stage #1: trans-butene-1,4-diol With sodium hydride In tetrahydrofuran at 20℃; for 0.75h;
Stage #2: tert-butyldimethylsilyl chloride In tetrahydrofuran at 20℃; for 0.75h; Further stages.;
89%
In N,N-dimethyl-formamide at 0 - 20℃; Inert atmosphere;89%
With 1H-imidazole In N,N-dimethyl-formamide at 0 - 20℃;89%
1H-imidazole
288-32-4

1H-imidazole

(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

(E)-4-[(tert-butyldimethylsilyl)oxy]-2-buten-1-ol
91202-69-6

(E)-4-[(tert-butyldimethylsilyl)oxy]-2-buten-1-ol

Conditions
ConditionsYield
In N,N-dimethyl-formamide89%
(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

propargyl bromide
106-96-7

propargyl bromide

(E)-1,4-bis(prop-2-yn-1-yloxy)but-2-ene
116938-78-4

(E)-1,4-bis(prop-2-yn-1-yloxy)but-2-ene

Conditions
ConditionsYield
Stage #1: trans-butene-1,4-diol With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 0.5h; Inert atmosphere;
Stage #2: propargyl bromide In N,N-dimethyl-formamide; toluene; mineral oil for 2h; Inert atmosphere;
89%
(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

benzyl bromide
100-39-0

benzyl bromide

(E)-4-(benzyloxy)-2-buten-1-ol
80885-30-9, 81028-03-7, 69152-88-1

(E)-4-(benzyloxy)-2-buten-1-ol

Conditions
ConditionsYield
Stage #1: trans-butene-1,4-diol With sodium hydride In tetrahydrofuran at 20℃; for 1.5h;
Stage #2: benzyl bromide In tetrahydrofuran for 1h; Reflux;
88.8%
Stage #1: trans-butene-1,4-diol With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 1h; Inert atmosphere;
Stage #2: benzyl bromide In tetrahydrofuran; mineral oil at 0 - 75℃; for 1h; Inert atmosphere;
87%
With sodium hydride In N,N-dimethyl-formamide85%
(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

tert-butylchlorodiphenylsilane
58479-61-1

tert-butylchlorodiphenylsilane

(E)-4-(tert-butyldiphenylsilyloxy)-2-buten-1-ol
92808-78-1

(E)-4-(tert-butyldiphenylsilyloxy)-2-buten-1-ol

Conditions
ConditionsYield
With n-butyllithium In tetrahydrofuran; hexane at -78 - 20℃;88%
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 20h;56%
With 1H-imidazole at 0℃; for 15h;48%
(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

2-(phenylsulfonyl)acetonitrile
7605-28-9

2-(phenylsulfonyl)acetonitrile

1-phenylsulfonyl-1-cyano-2-vinylcyclopropane

1-phenylsulfonyl-1-cyano-2-vinylcyclopropane

Conditions
ConditionsYield
With 1,1'-azodicarbonyl-dipiperidine; trimethylphosphane In tetrahydrofuran at 22℃; for 4h;88%
(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

acrylonitrile
107-13-1

acrylonitrile

(E)-3,3'-(but-2-ene-1,4-diylbis(oxy))dipropanenitrile

(E)-3,3'-(but-2-ene-1,4-diylbis(oxy))dipropanenitrile

Conditions
ConditionsYield
With potassium tert-butylate In neat (no solvent) at 20℃; for 0.333333h; Michael Addition; Inert atmosphere;88%
(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

1,2,4-trihydroxy-3-iodobutane

1,2,4-trihydroxy-3-iodobutane

Conditions
ConditionsYield
With dihydrogen peroxide; iodine In acetonitrile at 20℃; for 13h;87%
(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

cyclohexane-1,2-epoxide
286-20-4

cyclohexane-1,2-epoxide

2-[(E)-4-hydroxybut-2-enyloxy]cyclohexanol

2-[(E)-4-hydroxybut-2-enyloxy]cyclohexanol

Conditions
ConditionsYield
With boron trifluoride diethyl etherate In dichloromethane at 20℃; for 0.5h;87%
(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

3-chloro-3-oxopropanoic acid methyl ester
37517-81-0

3-chloro-3-oxopropanoic acid methyl ester

2,2'-(2E)-but-2-ene-1,4-diyl 3,3'-dimethyl dimalonate
915234-98-9

2,2'-(2E)-but-2-ene-1,4-diyl 3,3'-dimethyl dimalonate

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane at 0 - 20℃; for 1h;87%
(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

Zn(CD2I)2*DME

Zn(CD2I)2*DME

(R,R)-2,2-dideuterio-1,3-cyclopropanedimethanol
883223-46-9

(R,R)-2,2-dideuterio-1,3-cyclopropanedimethanol

Conditions
ConditionsYield
With (4S,5S)-2-butyl-N4,N4,N5,N5-tetramethyl-1,3,2-dioxaborolane-4,5-dicarboxamide In dichloromethane at -45 - 20℃; Charette cyclopropanation;86%
(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

methyl iodide
74-88-4

methyl iodide

(E)-1,4-dimethoxy-2-butene
22805-71-6

(E)-1,4-dimethoxy-2-butene

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran at 0 - 25℃; for 25h;86%
Stage #1: trans-butene-1,4-diol With sodium hydride In tetrahydrofuran; mineral oil at 0 - 5℃; for 1.33333h; Inert atmosphere;
Stage #2: methyl iodide In tetrahydrofuran; mineral oil at 16 - 19℃; for 16.5h;
(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

2-bromoisobutyric acid bromide
20769-85-1

2-bromoisobutyric acid bromide

A

1,2-bis(bromoisobutrylyoxy)-2-butene

1,2-bis(bromoisobutrylyoxy)-2-butene

B

1,2-bis(bromoisobutyryloxy)-2-butene

1,2-bis(bromoisobutyryloxy)-2-butene

Conditions
ConditionsYield
With triethylamine In tetrahydrofuranA n/a
B 85%
(E)-2-butene-1,4-diol
821-11-4

(E)-2-butene-1,4-diol

1-iodononane
4282-42-2

1-iodononane

C22H44O2

C22H44O2

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 0 - 80℃; for 72h;85%

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