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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Diethyl Phenylmalonate supplier in China

Cas:83-13-6

Min.Order:0 Metric Ton

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Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

High purity Diethyl phenylmalonate with good quality CAS NO.83-13-6

Cas:83-13-6

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

Type:Manufacturers

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Hefei TNJ chemical industry co.,ltd

1. Quality Our products meet MSDS safe standard and we have ISO and other certificate so yan can get high quality products from our company. 2. Price We are the company which is the joint of trade and industry so we cao provide the competiti

Diethyl phenylmalonate/CAS 83-13-6

Cas:83-13-6

Min.Order:1 Metric Ton

Negotiable

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Diethyl phenylmalonate

Cas:83-13-6

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% Diethyl phenylmalonate 83-13-6 ISO Producer

Cas:83-13-6

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem’s R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantiti

High purity Diethyl phenylmalonate 98% TOP1 supplier in China

Cas:83-13-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Phenylmalonic acid diethyl ester

Cas:83-13-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.

TIANFU CHEM 83-13-6 Diethyl phenylmalonate

Cas:83-13-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

Diethyl phenylmalonate

Cas:83-13-6

Min.Order:1 Kilogram

FOB Price: $100.0 / 150.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 83-13-6 with best quality

Cas:83-13-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Hot Sell Factory Supply Raw Material CAS 83-13-6 ,Diethyl phenylmalonate

Cas:83-13-6

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Diethyl phenylmalonate 83-13-6

Cas:83-13-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Pharmaceutical Intermediates Diethyl phenylmalonate CAS:83-13-6

Cas:83-13-6

Min.Order:25 Kilogram

FOB Price: $546.0 / 553.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

Diethyl phenylmalonate CAS:83-13-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic inter

Diethyl phenylmalonate CAS:83-13-6

Cas:83-13-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Diethyl phenylmalonate

Cas:83-13-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:83-13-6

Cas:83-13-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

Diethyl Phenylmalonate

Cas:83-13-6

Min.Order:0

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Triumph International Development Limilted

Appearance:white powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:Common products:Sea/Air/Courie

Diethyl phenylmalonate

Cas:83-13-6

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

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Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

Diethyl phenylmalonate

Cas:83-13-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Diethyl phenylmalonate

Cas:83-13-6

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Diethyl phenylmalonate

Cas:83-13-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hangzhou Lingrui Chemical Co.,Ltd.

83-13-6 Diethyl phenylmalonate Appearance:white powder Storage:room temperature Package:according to customers' requirements Application:Pharma intermediates Transportation:By air(EMS or EUB or FedEx or TNT ect...) or by sea(FOB or CIF or CNF ect..

83-13-6 Diethyl phenylmalonate

Cas:83-13-6

Min.Order:1 Gram

Negotiable

Type:Other

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Diethyl Phenylmalonate

Cas:83-13-6

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

Diethyl phenylmalonate

Cas:83-13-6

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

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HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:clear colourless to yellowish liquid after melting Storage:Keep away of light,cool place Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:Pharmaceutical

Diethyl phenylmalonate

Cas:83-13-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

Diethyl phenylmalonate

Cas:83-13-6

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

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Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Best PriceDiethyl phenylmalonate

Cas:83-13-6

Min.Order:0

Negotiable

Type:Trading Company

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Shanghai Minstar Chemical Co., Ltd

Product Name: Diethyl phenylmalonate CAS: 83-13-6 MF: C13H16O4 MW: 236.26 EINECS: 201-456-5 Mol File: 83-13-6.mol Diethyl phenylmalonate Structure Diethyl phenylmalonate Chemical Properties Melting point 16 °C (lit.) Boili

Diethyl phenylmalonate

Cas:83-13-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

Hot sale 99% purity Diethyl phenylmalonate CAS NO.83-13-6

Cas:83-13-6

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

Diethyl phenylmalonate

Cas:83-13-6

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

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Synthetic route

iodobenzene
591-50-4

iodobenzene

diethyl malonate
105-53-3

diethyl malonate

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

Conditions
ConditionsYield
With barium dihydroxide; sodium tetrachloropalladate(II) In N,N-dimethyl acetamide at 100℃; for 14h;100%
With N,N'-(1R,2R)-cyclohexane-1,2-diyl-bis-[1-(pyridine-2-yl)methanimine]; 3 A molecular sieve; caesium carbonate; copper(l) iodide In acetonitrile at 70℃; for 30h;93%
With copper(l) iodide; caesium carbonate In 1,4-dioxane at 70℃; for 2h;93%
bromobenzene
108-86-1

bromobenzene

diethyl malonate
105-53-3

diethyl malonate

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

Conditions
ConditionsYield
With barium dihydroxide; sodium tetrachloropalladate(II) In N,N-dimethyl acetamide at 100℃; for 14h;99%
With di-tert-butyl(neopentyl)phosphine; sodium hydride; bis(dibenzylideneacetone)-palladium(0) In toluene; mineral oil at 70℃; for 24h;89%
With tri-tert-butyl phosphine; sodium hydride; bis(dibenzylideneacetone)-palladium(0) In tetrahydrofuran at 70℃; for 1h;87%
chlorobenzene
108-90-7

chlorobenzene

diethyl malonate
105-53-3

diethyl malonate

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

Conditions
ConditionsYield
With barium dihydroxide; sodium tetrachloropalladate(II) In N,N-dimethyl acetamide at 100℃; for 14h;93%
With potassium phosphate; (1-adamantyl)di(tert-butyl) phosphine; bis(dibenzylideneacetone)-palladium(0) In toluene at 100℃;85%
Ethyl 2-phenylethanoate
101-97-3

Ethyl 2-phenylethanoate

polystyrene-o-nitrophenyl ethyl carbonate

polystyrene-o-nitrophenyl ethyl carbonate

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

Conditions
ConditionsYield
With polystyrene-trityllithium In tetrahydrofuran Ambient temperature;92%
diethyl (methylsulfonyl)phenylmalonate
154377-07-8

diethyl (methylsulfonyl)phenylmalonate

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

Conditions
ConditionsYield
Stage #1: diethyl phenyl(methylsulfonyl)malonate With 1,4-diaza-bicyclo[2.2.2]octane In toluene at 20℃; for 8h; Reflux;
Stage #2: With water
83%
With 1,4-diaza-bicyclo[2.2.2]octane; water 1.) toluene, reflux, 2.) room temperature; Yield given. Multistep reaction;
1,3-diethyl 2-diazopropanedioate
5256-74-6

1,3-diethyl 2-diazopropanedioate

benzene
71-43-2

benzene

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

Conditions
ConditionsYield
With trifluorormethanesulfonic acid In neat (no solvent) at 60℃; for 0.5h; Temperature; Friedel-Crafts Alkylation;82%
ethyl 1-imidazolecarboxylate
19213-72-0

ethyl 1-imidazolecarboxylate

Ethyl 2-phenylethanoate
101-97-3

Ethyl 2-phenylethanoate

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

Conditions
ConditionsYield
Stage #1: Ethyl 2-phenylethanoate With lithium hexamethyldisilazane In tetrahydrofuran at -78℃; for 0.5h;
Stage #2: ethyl 1-imidazolecarboxylate In tetrahydrofuran at -78 - 20℃;
81%
diethyl 2-chloro-2-phenylmalonate
107365-54-8

diethyl 2-chloro-2-phenylmalonate

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

Conditions
ConditionsYield
With zinc In water; acetic acid for 4h; Heating;80%
triphenylbismuth carbonate
47252-14-2

triphenylbismuth carbonate

diethyl malonate
105-53-3

diethyl malonate

A

diethyl 2,2-diphenylmalonate
97080-43-8

diethyl 2,2-diphenylmalonate

B

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

Conditions
ConditionsYield
In tetrahydrofuran at 67℃; for 11h;A 77%
B 18%
In tetrahydrofuran at 67℃; for 11h;A 13%
B 53%
1,3-diethyl 2-diazopropanedioate
5256-74-6

1,3-diethyl 2-diazopropanedioate

trimethyl(phenyl)stannane
934-56-5

trimethyl(phenyl)stannane

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

Conditions
ConditionsYield
With potassium fluoride; [Rh(OH)(cod)]2; XPhos In tetrahydrofuran; water at 70℃; for 1h; Stille Cross Coupling; Heating; Inert atmosphere;76%
1,1,3,3,3-pentafluoro-2-phenylpropene
1979-51-7

1,1,3,3,3-pentafluoro-2-phenylpropene

sodium ethanolate
141-52-6

sodium ethanolate

A

ethyl 3,3,3-trifluoro-2-phenylpropanoate
90784-42-2

ethyl 3,3,3-trifluoro-2-phenylpropanoate

B

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

C

(E)-3-Ethoxy-3-fluoro-2-phenyl-acrylic acid ethyl ester

(E)-3-Ethoxy-3-fluoro-2-phenyl-acrylic acid ethyl ester

Conditions
ConditionsYield
In acetonitrile at 25℃;A 74%
B 4%
C 4%
iodobenzene
591-50-4

iodobenzene

diethyl malonate
105-53-3

diethyl malonate

A

Ethyl 2-phenylethanoate
101-97-3

Ethyl 2-phenylethanoate

B

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

Conditions
ConditionsYield
With tri-tert-butyl phosphine; caesium carbonate; tris(dibenzylideneacetone)dipalladium (0) In 1,2-dimethoxyethane at 80℃; for 68h;A 11%
B 71%
With sodium hydride; copper(l) iodide In 1,4-dioxane at 101℃; for 5h; Title compound not separated from byproducts;A 3 % Chromat.
B 97 % Chromat.
copper(l) iodide In 1,4-dioxane at 101℃; for 5h; Product distribution; further solvents, catalysts and additives;A 3 % Chromat.
B 97 % Chromat.
(η6-fluorobenzene)tricarbonylchromium
12082-05-2

(η6-fluorobenzene)tricarbonylchromium

diethyl malonate
105-53-3

diethyl malonate

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

Conditions
ConditionsYield
With potassium hydroxide; iodine In diethyl ether; dimethyl sulfoxide addn. of C6H5CH(COOC2H5)2 to mixt. of Cr(CO)3-complex/powd. KOH in DMSO (stirring; 20°C, 6 h), diln. with aq. HCl, extn. with Et2O, treating with excess I2 (room temp., 3 h); distn. (reduced pressure); identification by GC and NMR;66%
1,3-diethyl 2-diazopropanedioate
5256-74-6

1,3-diethyl 2-diazopropanedioate

phenylboronic acid
98-80-6

phenylboronic acid

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

Conditions
ConditionsYield
With potassium phosphate; chloro(1,5-cyclooctadiene)rhodium(I) dimer In toluene at 80℃; for 10.5h; Inert atmosphere; Sealed tube; chemoselective reaction;63%
1,3-diethyl 2-diazopropanedioate
5256-74-6

1,3-diethyl 2-diazopropanedioate

phenyl trimethylsiloxane
2996-92-1

phenyl trimethylsiloxane

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

Conditions
ConditionsYield
With [Rh(OH)(cod)]2; tetrabutyl ammonium fluoride; tricyclohexylphosphine tetrafluoroborate In 1,4-dioxane; water at 100℃; for 5h; Hiyama Coupling; Inert atmosphere;62%
2-oxo-3-phenylbutanedioic acid diethyl ester
7147-33-3

2-oxo-3-phenylbutanedioic acid diethyl ester

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

Conditions
ConditionsYield
at 170 - 180℃; for 12h;61%
under 20 - 40 Torr; bei der Destillation;
(phenylmethylene)bis(4,4,5,5‐tetramethyl‐1,3,2‐dioxaborolane)

(phenylmethylene)bis(4,4,5,5‐tetramethyl‐1,3,2‐dioxaborolane)

Diethyl carbonate
105-58-8

Diethyl carbonate

A

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

B

1,3-Diphenylpropanone
102-04-5

1,3-Diphenylpropanone

Conditions
ConditionsYield
With lithium tert-butoxide In tetrahydrofuran at 23℃; for 3h; Glovebox;A 21%
B 33%
diethyl α-bromophenylmalonate
69836-07-3

diethyl α-bromophenylmalonate

toluene
108-88-3

toluene

A

phenyl-p-tolyl-malonic acid diethyl ester
108802-89-7

phenyl-p-tolyl-malonic acid diethyl ester

B

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

Conditions
ConditionsYield
With antimony pentafluoride 1.) SO2, -65 deg C, 2.) -65 deg C to RT; Yield given. Multistep reaction;A n/a
B 28%
diphenyliodonium tetrafluoroborate

diphenyliodonium tetrafluoroborate

diethyl malonate
105-53-3

diethyl malonate

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 70℃; for 4h; Phenylation;27%
1,3-diethyl 2-diazopropanedioate
5256-74-6

1,3-diethyl 2-diazopropanedioate

benzene
71-43-2

benzene

(1R*,5R*)-diethyl Bicyclo[3.2.0]hepta-2,6-diene-2,6-dicarboxylate

(1R*,5R*)-diethyl Bicyclo[3.2.0]hepta-2,6-diene-2,6-dicarboxylate

B

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

Conditions
ConditionsYield
at 20℃; for 17h; Mechanism; Inert atmosphere; Sealed tube; Photolysis;A 17%
B 18%
diethyl α-bromophenylmalonate
69836-07-3

diethyl α-bromophenylmalonate

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

Conditions
ConditionsYield
With antimony pentafluoride; benzene Product distribution; 1.) SO2, -65 deg C; 2.) -65 deg C to RT;13%
tetrachloromethane
56-23-5

tetrachloromethane

ethyl 2-diazo-3-oxo-3-phenylpropanoate
28383-65-5

ethyl 2-diazo-3-oxo-3-phenylpropanoate

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

Conditions
ConditionsYield
Behandeln des Reaktionsproduktes mit verd. Natriumaethylat-Loesung;
ethyl 2-diazo-3-oxo-3-phenylpropanoate
28383-65-5

ethyl 2-diazo-3-oxo-3-phenylpropanoate

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

Conditions
ConditionsYield
at 250℃; under 11 Torr;
With xylene Behandeln des Reaktionsproduktes mit verd. Natriumaethylat-Loesung;
at 250℃; under 11 Torr;
Ethyl 2-phenylethanoate
101-97-3

Ethyl 2-phenylethanoate

oxalic acid diethyl ester
95-92-1

oxalic acid diethyl ester

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

Conditions
ConditionsYield
With sodium ethanolate Erhitzen des Reaktionsprodukts unter 200 Tor auf 140-150grad;
Ethyl 2-phenylethanoate
101-97-3

Ethyl 2-phenylethanoate

Diethyl carbonate
105-58-8

Diethyl carbonate

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

Conditions
ConditionsYield
With sodium ethanolate under 125 Torr; unter Entfernen des entstehenden Aethanols;
With sodium hydride In tetrahydrofuran at 0℃; for 4h; Reflux;
Ethyl 2-phenylethanoate
101-97-3

Ethyl 2-phenylethanoate

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

Conditions
ConditionsYield
With ammonia; sodium amide Erwaermen des Reaktionsprodukts mit Kohlensaeure-diaethylester in Aether;
With diethyl ether; potassium at 20℃; Behandlung des Reaktionsprodukts mit Chlorameisensaeure-aethylester;
Multi-step reaction with 2 steps
1: sodium ethanolate
2: 12 h / 170 - 180 °C
View Scheme
oxalic acid diethyl ester
95-92-1

oxalic acid diethyl ester

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

Conditions
ConditionsYield
With ethanol; sodium at 60℃; man zersetzt das Natriumsalz mit verd. Schwefelsaeure und erhitzt bei etwa 15 mm auf 175grad;
ethyl phenylcyanoacetate
4553-07-5

ethyl phenylcyanoacetate

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

Conditions
ConditionsYield
With hydrogenchloride; ethanol
ethanol
64-17-5

ethanol

Phenylmalonic dibromide
83392-44-3

Phenylmalonic dibromide

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

Conditions
ConditionsYield
With 2-oxo-3-trimethyltetrahydro-1,3-oxazole for 0.25h; Ambient temperature; Yield given;
ethyl trimethylsilyl ether
1825-62-3

ethyl trimethylsilyl ether

Phenylmalonic dibromide
83392-44-3

Phenylmalonic dibromide

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

Conditions
ConditionsYield
In dichloromethane at 15℃; for 15h; Yield given;
diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

2-phenylpropane-1, 3-diol
1570-95-2

2-phenylpropane-1, 3-diol

Conditions
ConditionsYield
With diisobutylaluminium hydride In tetrahydrofuran for 2h; Mechanism; Product distribution; Ambient temperature; other reducing agents, var. time;100%
With diisobutylaluminium hydride In tetrahydrofuran for 2h; Ambient temperature;100%
Stage #1: diethyl 2-phenylmalonate With sodium hydroxide In tetrahydrofuran; water at 145℃; under 2280.15 Torr; for 0.933333h; Inert atmosphere;
Stage #2: With tetrabutyl-ammonium chloride In tetrahydrofuran; water for 0.183333h; Inert atmosphere;
Stage #3: With sodium hydroxide In tetrahydrofuran; water; toluene at 156℃; under 3800.26 Torr; for 3.13333h; Solvent; Temperature; Pressure; Inert atmosphere;
99.6%
2-Amino-2-methyl-1-propanol
124-68-5

2-Amino-2-methyl-1-propanol

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

N,N'-bis(1-hydroxy-2-methylpropan-2-yl)-2-phenylmalonamide

N,N'-bis(1-hydroxy-2-methylpropan-2-yl)-2-phenylmalonamide

Conditions
ConditionsYield
With sodium hydride In mineral oil at 160℃; Inert atmosphere;100%
diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

diethyl α-bromophenylmalonate
69836-07-3

diethyl α-bromophenylmalonate

Conditions
ConditionsYield
With cetyltrimethylammonim bromide; manganese triacetate In acetic acid at 70℃; for 2h;99%
Stage #1: diethyl 2-phenylmalonate With sodium hydride In tetrahydrofuran
Stage #2: With dibromamine-B In tetrahydrofuran; dichloromethane at 0℃; for 1h;
88%
Stage #1: diethyl 2-phenylmalonate With sodium hydride In tetrahydrofuran at 0℃;
Stage #2: With N-Bromosuccinimide In tetrahydrofuran for 0.25h;
63%
propargyl bromide
106-96-7

propargyl bromide

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

diethyl 2-phenyl-2-(prop-2-yn-1-yl)malonate
51632-37-2

diethyl 2-phenyl-2-(prop-2-yn-1-yl)malonate

Conditions
ConditionsYield
Stage #1: diethyl 2-phenylmalonate With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; for 0.5h;
Stage #2: propargyl bromide In tetrahydrofuran; toluene; mineral oil at 0 - 20℃;
99%
(i) NaOEt, EtOH, (ii) /BRN= 605309/; Multistep reaction;
diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

α-Amino-α-phenyl-malonsaeure-diaethylester
22225-53-2

α-Amino-α-phenyl-malonsaeure-diaethylester

Conditions
ConditionsYield
Stage #1: diethyl 2-phenylmalonate With sodium hydride In tetrahydrofuran at 23℃; for 0.25h;
Stage #2: With O-(4-nitrobenzoyl) hydroxylamine In tetrahydrofuran at 23℃;
99%
With sodium hydride; O-(2,4-dinitrophenyl)hydroxylamine
(i) NaH, THF, (ii) O-(2,4-dinitro-phenyl)-hydroxylamine; Multistep reaction;
diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

(4-methylphenyl)methyl carbonate
270921-38-5

(4-methylphenyl)methyl carbonate

diethyl [(4-methylphenyl)methyl](phenyl)malonate

diethyl [(4-methylphenyl)methyl](phenyl)malonate

Conditions
ConditionsYield
With 1,1'-bis-(diphenylphosphino)ferrocene; 1,5-cis,cis-cyclooctadiene; [PdCp(η3-C3H5)] In tetrahydrofuran at 80℃;99%
With 1,1'-bis-(diphenylphosphino)ferrocene; N,O-bis-(trimethylsilyl)-acetamide; {(η4-1,5-cyclooctadiene)Pd(η3-allyl)}BF4; potassium acetate In tetrahydrofuran at 80℃; for 24h;98%
diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

(4-methoxyphenyl)methyl methyl carbonate
270921-39-6

(4-methoxyphenyl)methyl methyl carbonate

diethyl [(4-methoxyphenyl)methyl](phenyl)malonate
95002-44-1

diethyl [(4-methoxyphenyl)methyl](phenyl)malonate

Conditions
ConditionsYield
With 1,1'-bis(diisopropylphosphino)ferrocene; {(η4-1,5-cyclooctadiene)Pd(η3-allyl)}BF4; caesium carbonate In N,N-dimethyl-formamide at 30℃; for 24h; Inert atmosphere;99%
With 1,1'-bis-(diphenylphosphino)ferrocene; 1,5-cis,cis-cyclooctadiene; [PdCp(η3-C3H5)] In tetrahydrofuran at 80℃; for 3h;98%
With 1,1'-bis-(diphenylphosphino)ferrocene; N,O-bis-(trimethylsilyl)-acetamide; {(η4-1,5-cyclooctadiene)Pd(η3-allyl)}BF4; potassium acetate In tetrahydrofuran at 80℃; for 4h;94%
diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

[4-(methoxycarbonyl)phenyl]methyl methyl carbonate

[4-(methoxycarbonyl)phenyl]methyl methyl carbonate

diethyl [{4-(methoxycarbonyl)phenyl}methyl](phenyl)malonate

diethyl [{4-(methoxycarbonyl)phenyl}methyl](phenyl)malonate

Conditions
ConditionsYield
With 1,1'-bis-(diphenylphosphino)ferrocene; 1,5-cis,cis-cyclooctadiene; [PdCp(η3-C3H5)] In tetrahydrofuran at 80℃;99%
With 1,1'-bis-(diphenylphosphino)ferrocene; N,O-bis-(trimethylsilyl)-acetamide; {(η4-1,5-cyclooctadiene)Pd(η3-allyl)}BF4; potassium acetate In tetrahydrofuran at 80℃; for 24h;86%
With 1,1'-bis(diisopropylphosphino)ferrocene; {(η4-1,5-cyclooctadiene)Pd(η3-allyl)}BF4; caesium carbonate In N,N-dimethyl-formamide at 30℃; for 4h; Inert atmosphere;84%
diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

methyl 2-naphthalenylmethyl carbonate

methyl 2-naphthalenylmethyl carbonate

diethyl [(2-naphthyl)methyl](phenyl)malonate

diethyl [(2-naphthyl)methyl](phenyl)malonate

Conditions
ConditionsYield
With 1,1'-bis-(diphenylphosphino)ferrocene; [PdCp(η3-C3H5)] In tetrahydrofuran at 80℃; for 1h;99%
diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

methyl (naphthalen-1-ylmethyl) carbonate

methyl (naphthalen-1-ylmethyl) carbonate

diethyl [(1-naphthyl)methyl](phenyl)malonate

diethyl [(1-naphthyl)methyl](phenyl)malonate

Conditions
ConditionsYield
With 1,1'-bis-(diphenylphosphino)ferrocene; [PdCp(η3-C3H5)] In tetrahydrofuran at 80℃; for 1h;99%
3-acetoxy-1,3-diphenylpropene
73930-97-9

3-acetoxy-1,3-diphenylpropene

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

C28H28O4

C28H28O4

Conditions
ConditionsYield
With bis(η3-allyl-μ-chloropalladium(II)); C24H31O2P; lithium acetate; bis-(trimethylsilyl)acetamide In dichloromethane at -20℃; for 10h; Inert atmosphere; optical yield given as %ee;99%
<2H9>trimethylsulphoxonium iodide
23726-00-3

<2H9>trimethylsulphoxonium iodide

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

diethyl 2-(methyl-d3)-2-phenylmalonate

diethyl 2-(methyl-d3)-2-phenylmalonate

Conditions
ConditionsYield
Stage #1: diethyl 2-phenylmalonate With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 0.5h; Sealed tube;
Stage #2: <2H9>trimethylsulphoxonium iodide In tetrahydrofuran; mineral oil at 80℃; for 8h; Sealed tube;
99%
diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

methyl iodide
74-88-4

methyl iodide

diethyl 2-methyl-2-phenylmalonate
34009-61-5

diethyl 2-methyl-2-phenylmalonate

Conditions
ConditionsYield
Stage #1: diethyl 2-phenylmalonate With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.166667h;
Stage #2: methyl iodide In N,N-dimethyl-formamide for 18h;
98%
With sodium ethanolate In ethanol for 3h; Heating;81%
Stage #1: diethyl 2-phenylmalonate With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 0.5h; Inert atmosphere; Schlenk technique;
Stage #2: methyl iodide In tetrahydrofuran; mineral oil at 0 - 20℃; for 36h; Inert atmosphere; Schlenk technique;
75%
benzyl methyl carbonate
13326-10-8

benzyl methyl carbonate

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

diethyl 2-benzyl-2-phenylmalonate
613670-59-0

diethyl 2-benzyl-2-phenylmalonate

Conditions
ConditionsYield
With 1,1'-bis(diisopropylphosphino)ferrocene; {(η4-1,5-cyclooctadiene)Pd(η3-allyl)}BF4; caesium carbonate In N,N-dimethyl-formamide at 30℃; for 48h; Inert atmosphere;98%
With 1,1'-bis-(diphenylphosphino)ferrocene; N,O-bis-(trimethylsilyl)-acetamide; {(η4-1,5-cyclooctadiene)Pd(η3-allyl)}BF4; potassium acetate In tetrahydrofuran at 80℃; for 24h;95%
With 1,1'-bis-(diphenylphosphino)ferrocene; 1,5-cis,cis-cyclooctadiene; [PdCp(η3-C3H5)] In tetrahydrofuran at 80℃;84%
diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

hydroxyphenylmalonic acid diethyl ester
73640-03-6

hydroxyphenylmalonic acid diethyl ester

Conditions
ConditionsYield
With 10% Pd on charcoal; oxygen; triethylamine In ethanol at 20℃; for 6h;98%
With 5%-palladium/activated carbon; triethylamine In ethanol at 20℃; for 5h; Reagent/catalyst;98%
With Pd2hpp4; 1,3,4,6,7,8-hexahydro-2H-pyrimido[1,2-a]pyrimidine; oxygen In tetrahydrofuran at 6℃; under 760.051 Torr; for 12h; regioselective reaction;97%
With iodine; sodium acetate In tetrahydrofuran; water at 35℃; for 5h; Irradiation; Green chemistry;88%
diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

ethyl 2-(hydroxyimino)-2-phenylacetate
131934-09-3, 135765-81-0, 712-41-4

ethyl 2-(hydroxyimino)-2-phenylacetate

Conditions
ConditionsYield
With sulfuric acid; potassium carbonate; sodium nitrite In ethanol; water at 10℃; for 5h;97.2%
trans-geranyl bromide
6138-90-5

trans-geranyl bromide

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

(E)-diethyl 2-[3,7-dimethylocta-2,6-dienyl]-2-phenylmalonate
16725-60-3

(E)-diethyl 2-[3,7-dimethylocta-2,6-dienyl]-2-phenylmalonate

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran at 20℃; for 0.0833333h; Inert atmosphere;97%
With sodium ethanolate In ethanol
4-methoxy-aniline
104-94-9

4-methoxy-aniline

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

4-hydroxy-6-methoxy-3-phenyl-2(1H)-quinolinone
28563-21-5

4-hydroxy-6-methoxy-3-phenyl-2(1H)-quinolinone

Conditions
ConditionsYield
In diphenylether at 250 - 300℃; for 3h;97%
71%
at 260 - 270℃;71%
diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

methyl (2-methylphenyl)methyl carbonate

methyl (2-methylphenyl)methyl carbonate

diethyl [(2-methylphenyl)methyl](phenyl)malonate

diethyl [(2-methylphenyl)methyl](phenyl)malonate

Conditions
ConditionsYield
With 1,1'-bis(diisopropylphosphino)ferrocene; {(η4-1,5-cyclooctadiene)Pd(η3-allyl)}BF4; caesium carbonate In N,N-dimethyl-formamide at 50℃; for 24h; Inert atmosphere;97%
With 1,1'-bis-(diphenylphosphino)ferrocene; 1,5-cis,cis-cyclooctadiene; [PdCp(η3-C3H5)] In tetrahydrofuran at 80℃;90%
rac-(E)-1,3-diphenyl-3-acetoxy-prop-1-ene
87751-69-7

rac-(E)-1,3-diphenyl-3-acetoxy-prop-1-ene

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

(S,E)-diethyl 2-(1,3-diphenylallyl)-2-phenylmalonate

(S,E)-diethyl 2-(1,3-diphenylallyl)-2-phenylmalonate

Conditions
ConditionsYield
With N,O-bis-(trimethylsilyl)-acetamide; bis(η3-allyl-μ-chloropalladium(II)); N-[(S)-1-(2-(diphenylphosphino)phenyl)ethyl]-1,7,7-trimethylbicyclo[2,2,1]heptan-2-imine; cesium acetate In toluene at 20℃; enantioselective reaction;97%
With N,O-bis-(trimethylsilyl)-acetamide; bis(η3-allyl-μ-chloropalladium(II)); (S)-7-(diphenylphosphino)-2′-isopropyl-2,3-dihydro-5′H-spiro[indene-1,4′-oxazole]; potassium acetate In toluene at 0℃; for 5h; Inert atmosphere; Schlenk technique; enantioselective reaction;91%
C12H10(2)HF2NO6S

C12H10(2)HF2NO6S

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

C14H15(2)HF2O4

C14H15(2)HF2O4

Conditions
ConditionsYield
Stage #1: diethyl 2-phenylmalonate With lithium tert-butoxide In acetonitrile at 20℃; for 0.166667h;
Stage #2: C12H10(2)HF2NO6S In acetonitrile at 20℃; for 0.166667h;
97%
(6-methoxynaphthalen-2-yl)methyl 2,3,4,5,6-pentafluorobenzoate

(6-methoxynaphthalen-2-yl)methyl 2,3,4,5,6-pentafluorobenzoate

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

diethyl 2-((6-methoxynaphthalen-2-yl)methyl)-2-phenylmalonate

diethyl 2-((6-methoxynaphthalen-2-yl)methyl)-2-phenylmalonate

Conditions
ConditionsYield
With 2-Picolinic acid; bis[dichloro(pentamethylcyclopentadienyl)ruthenium(III)]; caesium carbonate In acetonitrile at 60℃; for 18h; Inert atmosphere;97%
2-(2-bromoethoxy)tetrahydropyran
17739-45-6, 59146-56-4

2-(2-bromoethoxy)tetrahydropyran

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

(tetrahydropyrannyl-2 oxy)-2 ethyl phenyl malonate de diethyle
106996-59-2

(tetrahydropyrannyl-2 oxy)-2 ethyl phenyl malonate de diethyle

Conditions
ConditionsYield
With hydrogenchloride In N,N-dimethyl-formamide96%
With potassium tert-butylate 1.) t-butanol, 70 deg. C, 2 h; 2.) 70 deg C, 10 h; Yield given. Multistep reaction;
diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

Diethyl [α-2H]phenylmalonate
300537-13-7

Diethyl [α-2H]phenylmalonate

Conditions
ConditionsYield
Stage #1: diethyl 2-phenylmalonate With sodium hydride In tetrahydrofuran for 5h; Metallation; Heating;
Stage #2: With diclazuril; water-d2 Substitution; Deuteration; Further stages.;
96%
diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

[(4-trifluoromethyl)phenyl]methyl methyl carbonate
270921-40-9

[(4-trifluoromethyl)phenyl]methyl methyl carbonate

diethyl [{4-(trifluoromethyl)phenyl}methyl](phenyl)malonate

diethyl [{4-(trifluoromethyl)phenyl}methyl](phenyl)malonate

Conditions
ConditionsYield
With 1,1'-bis(diisopropylphosphino)ferrocene; {(η4-1,5-cyclooctadiene)Pd(η3-allyl)}BF4; caesium carbonate In N,N-dimethyl-formamide at 30℃; for 24h; Inert atmosphere;96%
With 1,1'-bis-(diphenylphosphino)ferrocene; 1,5-cis,cis-cyclooctadiene; [PdCp(η3-C3H5)] In tetrahydrofuran at 80℃;90%
With 1,1'-bis-(diphenylphosphino)ferrocene; N,O-bis-(trimethylsilyl)-acetamide; {(η4-1,5-cyclooctadiene)Pd(η3-allyl)}BF4; potassium acetate In tetrahydrofuran at 80℃; for 48h;78%
4-hydroxy-6-methyl-2-pyridone
3749-51-7

4-hydroxy-6-methyl-2-pyridone

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

C15H11NO4
955377-04-5

C15H11NO4

Conditions
ConditionsYield
In diphenylether Heating;96%
diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

3-amino-4,6-dimethylpyrazolo[3,4-b]pyridine
41601-44-9

3-amino-4,6-dimethylpyrazolo[3,4-b]pyridine

4-hydroxy-8,10-dimethyl-3-phenylpyrido[2',3':3,4]pyrazolo[1,5-a]pyrimidin-2(1H)-one
1220996-95-1

4-hydroxy-8,10-dimethyl-3-phenylpyrido[2',3':3,4]pyrazolo[1,5-a]pyrimidin-2(1H)-one

Conditions
ConditionsYield
In diphenylether at 220 - 250℃;96%
(Z)-3-bromo-5-triisopropylsilyl-1,3-pentadiene
1187617-25-9

(Z)-3-bromo-5-triisopropylsilyl-1,3-pentadiene

diethyl 2-phenylmalonate
83-13-6

diethyl 2-phenylmalonate

diethyl 2-phenyl-2-[5-(triisopropylsilyl)penta-2,3-dienyl]propane-1,3-dioate
1370439-84-1

diethyl 2-phenyl-2-[5-(triisopropylsilyl)penta-2,3-dienyl]propane-1,3-dioate

Conditions
ConditionsYield
With (PdAllylCl)2; sodium hydride; 2,2'-bis(diphenylphosphino)biphenyl In tetrahydrofuran at 23℃; for 12h; Inert atmosphere;96%

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