Products

Refine

Country

Business Type

Certificate

Display

Hangzhou Think Chemical Co. Ltd

HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about ten years of business experiences on the marketing & distribution, thinkchem specializes in exp

High quality of Canrenone with best price for sale

Cas:976-71-6

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Hangzhou Yunuo Chemical Co., Ltd is located in Hangzhou city China. As a global supplier in the chemical industry, Yunuochem is to create added value for customers around the world. Sticking to such business idea of "Good faith wins the busine

Pregna-4,6-diene-21-carboxylicacid, 17-hydroxy-3-oxo-, g-lactone, (17a)-

Cas:976-71-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Sinoway Industrial Co., Ltd.

Why is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c

99% up GMP DMF Canrenone 976-71-6

Cas:976-71-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Appearance Yellow Powder Complies Identification Corresponds to the retenti

High quality Canrenone with best price cas:976-71-6

Cas:976-71-6

Min.Order:1 Kilogram

FOB Price: $250.0 / 350.0

Type:Trading Company

inquiry

Kono Chem Co.,Ltd

Canrenone is an active metabolite of spironolactone that acts as an MCR antagonist, inhibiting aldosterone biosynthesis. it also blocks ouabain effects. Specification Analysis Test

CAS:976-71-6 Canrenone

Cas:976-71-6

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Wuhan Fortuna Chemical Co.,Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; ...... Appearance:Yellow crystalline powder Storage:Store at RT Package:1kg/foi

Favorable price Canrenone CAS 976-71-6 supplied by manufacturer

Cas:976-71-6

Min.Order:1 Kilogram

FOB Price: $600.0 / 800.0

Type:Trading Company

inquiry

Hebei yanxi chemical co.,LTD.

Hebei yanxi chemical co., LTD is a professional research, development and production enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low carbon environmental protection safety

Canrenone

Cas:976-71-6

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

Type:Manufacturers

inquiry

Hefei TNJ chemical industry co.,ltd

Good products, good service. We have professional sales team working on sales service for 15 years. Good products can win good market but can not stand long without good service. We have strict sales regulation and service procedure to make sure yo

TNJ High Purity Slightly Yellow Canrenone

Cas:976-71-6

Min.Order:50 Kilogram

Negotiable

Type:Trading Company

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Canrenone

Cas:976-71-6

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% Canrenone 90% 976-71-6 GMP manufacturer

Cas:976-71-6

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermedi

Canrenone

Cas:976-71-6

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

inquiry

Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality canrenone

Cas:976-71-6

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Canrenone

Cas:976-71-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Product Name: Canrenone Synonyms: 11614r.p;17-(2-Carboxyethyl)17-hydroxy-3-oxoandrosta-4,6-dienelactone;17-(2-Carboxyethyl)17-hydroxyandrosta-4,6-dien-3-onelactone;17-hydroxy-3-oxo-,gamma-lactone,(17-alpha)-pregna-6-diene-21-carboxylicacid;17-Hydr

976-71-6 Canrenone

Cas:976-71-6

Min.Order:1 Kilogram

FOB Price: $500.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufactu

Food Additives Canrenoate CAS 976-71-6

Cas:976-71-6

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Canrenone/ LIDE PHARMA- Factory supply / Best price

Cas:976-71-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Appearance:white to beige powder Storage:room temperature Package:25kg/drum Application:antiinflammatory, glucocorticoid Transportation:Express/Sea/Air Port:any port in china

Canrenone factory price

Cas:976-71-6

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Pregna-4,6-diene-21-carboxylicacid, 17-hydroxy-3-oxo-, g-lactone, (17a)- 976-71-6

Cas:976-71-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

Carbonyl compounds,Canrenone API CAS NO.:976-71-6

Cas:976-71-6

Min.Order:1 Kilogram

FOB Price: $470.0 / 500.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

Canrenone CAS: 976-71-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates, s

Canrenone CAS: 976-71-6

Cas:976-71-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Pregna-4,6-diene-21-carboxylicacid, 17-hydroxy-3-oxo-, g-lactone, (17a)-

Cas:976-71-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Terui OP New Material Technology Co., Ltd.

We have overseas warehouses in California, Nuevo Laredo, Mexico, Vancouver, Canada, Amsterdam, The Netherlands and Melbourne, Australia. Overseas warehouses can provide some of the best selling products. We look forward to cooperating with strong loc

Hot selling cas 976-71-6 Canrenone Safely delivered to USA, Mexico, Canada

Cas:976-71-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Pregna-4,6-diene-21-carboxylicacid, 17-hydroxy-3-oxo-, g-lactone, (17a)-

Cas:976-71-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Triumph International Development Limilted

Lorcaserin(856681-05-5)is an orally administered agent and a selective 5-HT2C receptor agonist for the treatment of obesity. It had been approved for marketing in US by FDA on 27 June in 2012. In clinical studies, lorcaserin h

Canrenone

Cas:976-71-6

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Taizhou Crene Biotechnology co.ltd

Our company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-

NSC-261713 Canrenone 976-71-6

Cas:976-71-6

Min.Order:5 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Canrenone

Cas:976-71-6

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Canrenone

Cas:976-71-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

Canrenone

Cas:976-71-6

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Canrenone

Cas:976-71-6

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

Canrenone

Cas:976-71-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

SPIRONOLACTONE
52-01-7

SPIRONOLACTONE

canrenone
976-71-6

canrenone

Conditions
ConditionsYield
With mercury dichloride In ethanol Ambient temperature;95%
With sodium methylate In tetrahydrofuran at 20℃; for 18h; Elimination;72%
With potassium dihydrogenphosphate In ethanol at 40℃; Rate constant; Kinetics; Thermodynamic data; var. buffers, pH, temp., ionic strengh, spironolactone and buffer conc.; energy of activation;
potassium canrenoate

potassium canrenoate

canrenone
976-71-6

canrenone

Conditions
ConditionsYield
With NH2SO4 In methanol for 0.0833333h; Heating;92%
With hydrogenchloride In chloroform for 8h; Heating;86%
With acetic acid for 0.5h; Heating;
17β-hydroxy-3-ethoxy-17α-pregna-3,5-diene-21-carboxylic acid-γ-lactone

17β-hydroxy-3-ethoxy-17α-pregna-3,5-diene-21-carboxylic acid-γ-lactone

canrenone
976-71-6

canrenone

Conditions
ConditionsYield
With chloranil In methanol; water; 1,2-dichloro-ethane at 20℃; for 1h;84%
17β-hydroxy-3-ethoxy-17α-pregn-3,5-diene-21-carboxylic acid-γ-lactone

17β-hydroxy-3-ethoxy-17α-pregn-3,5-diene-21-carboxylic acid-γ-lactone

canrenone
976-71-6

canrenone

Conditions
ConditionsYield
Stage #1: 17β-hydroxy-3-ethoxy-17α-pregn-3,5-diene-21-carboxylic acid-γ-lactone With chloranil In methanol; dichloromethane; water at 20℃; for 1h;
Stage #2: With sodium thiosulfate In methanol; water at 20℃; for 1h;
83%
3-oxopregn-4-ene-21,17α-carbolactone
976-70-5

3-oxopregn-4-ene-21,17α-carbolactone

canrenone
976-71-6

canrenone

Conditions
ConditionsYield
With chloranil In tert-butyl alcohol Heating;70%
With chloranil; toluene-4-sulfonic acid; xylene
SPIRONOLACTONE
52-01-7

SPIRONOLACTONE

A

canrenone
976-71-6

canrenone

B

Chloronone
79327-11-0

Chloronone

Conditions
ConditionsYield
With mercury dichloride In ethanol for 2h; Heating;A 38%
B 54%
Conditions
ConditionsYield
Yield given. Multistep reaction;
levonorgestrel
434-03-7

levonorgestrel

canrenone
976-71-6

canrenone

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 98 percent / trimethyl orthoformate, p-toluenesulfonic acid / methanol / 3 h / 50 °C
2: H2, triphenylphosphine, rhodium acetate dimer / ethyl acetate / 20 h / 80 °C / 9000.7 Torr
3: 100 percent / N-methylmorpholine N-oxide (NMO), RuCl2(Ph3P)3 / dimethylformamide / 0.17 h
4: 97 percent / 6 N HCl / tetrahydrofuran / 0.5 h
5: 70 percent / p-chloranil / 2-methyl-propan-2-ol / Heating
View Scheme
17α-ethynyl-17β-hydroxy-5-androsten-3-one ethylene ketal
50407-76-6

17α-ethynyl-17β-hydroxy-5-androsten-3-one ethylene ketal

canrenone
976-71-6

canrenone

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: H2, triphenylphosphine, rhodium acetate dimer / ethyl acetate / 20 h / 80 °C / 9000.7 Torr
2: 100 percent / N-methylmorpholine N-oxide (NMO), RuCl2(Ph3P)3 / dimethylformamide / 0.17 h
3: 97 percent / 6 N HCl / tetrahydrofuran / 0.5 h
4: 70 percent / p-chloranil / 2-methyl-propan-2-ol / Heating
View Scheme
5'-hydroxyspiro-5-en-3-one
121936-43-4

5'-hydroxyspiro-5-en-3-one

canrenone
976-71-6

canrenone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 100 percent / N-methylmorpholine N-oxide (NMO), RuCl2(Ph3P)3 / dimethylformamide / 0.17 h
2: 97 percent / 6 N HCl / tetrahydrofuran / 0.5 h
3: 70 percent / p-chloranil / 2-methyl-propan-2-ol / Heating
View Scheme
C24H34O4
75219-50-0

C24H34O4

canrenone
976-71-6

canrenone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 97 percent / 6 N HCl / tetrahydrofuran / 0.5 h
2: 70 percent / p-chloranil / 2-methyl-propan-2-ol / Heating
View Scheme
3-(3-oxo-7α-thio-17β-hydroxy-4-androsten-17α-yl)propionic acid γ-lactone
38753-76-3

3-(3-oxo-7α-thio-17β-hydroxy-4-androsten-17α-yl)propionic acid γ-lactone

methyl iodide
74-88-4

methyl iodide

A

canrenone
976-71-6

canrenone

B

7-Thiomethylspirolactone
38753-77-4

7-Thiomethylspirolactone

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran at 20℃; for 2h;
3-(3-oxo-7α-thio-17β-hydroxy-4-androsten-17α-yl)propionic acid γ-lactone
38753-76-3

3-(3-oxo-7α-thio-17β-hydroxy-4-androsten-17α-yl)propionic acid γ-lactone

canrenone
976-71-6

canrenone

Conditions
ConditionsYield
With sodium methylate; methyl iodide In methanol at 20℃; for 1h;
SPIRONOLACTONE
52-01-7

SPIRONOLACTONE

A

3-(3-oxo-7α-thio-17β-hydroxy-4-androsten-17α-yl)propionic acid γ-lactone
38753-76-3

3-(3-oxo-7α-thio-17β-hydroxy-4-androsten-17α-yl)propionic acid γ-lactone

B

canrenone
976-71-6

canrenone

Conditions
ConditionsYield
With sodium hypochlorite; octabromotetrakis(2,6-dichlorophenyl)porphyrin Fe(III)Cl In water; acetonitrile at 80℃; for 0.833333h; Microwave irradiation;
With curvularia lunata Microbiological reaction;
Androstenedione
63-05-8

Androstenedione

canrenone
976-71-6

canrenone

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: potassium hydroxide / tetrahydrofuran / 6.5 h / 15 - 20 °C / Inert atmosphere
2: 5%-palladium/activated carbon; hydrogen / ethanol / 5 h / 20 - 30 °C / Inert atmosphere
3: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; potassium bromide; sodium hypochlorite; tetrabutyl-ammonium chloride / dichloromethane / 6 h / 10 - 15 °C
4: pyridine; sodium acetate; acetic acid; N-Bromosuccinimide / acetone; water / 2 h / -2 - 2 °C
5: lithium carbonate; lithium bromide / N,N-dimethyl-formamide / 3 h / 100 - 105 °C
View Scheme
C22H29BrO3

C22H29BrO3

canrenone
976-71-6

canrenone

Conditions
ConditionsYield
With lithium carbonate; lithium bromide In N,N-dimethyl-formamide at 100 - 105℃; for 3h;7.8 g
17,23-dihydroxy-21,24-dinor-17βH-chol-4-en-20-yn-3-one
55542-26-2

17,23-dihydroxy-21,24-dinor-17βH-chol-4-en-20-yn-3-one

canrenone
976-71-6

canrenone

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 5%-palladium/activated carbon; hydrogen / ethanol / 5 h / 20 - 30 °C / Inert atmosphere
2: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; potassium bromide; sodium hypochlorite; tetrabutyl-ammonium chloride / dichloromethane / 6 h / 10 - 15 °C
3: pyridine; sodium acetate; acetic acid; N-Bromosuccinimide / acetone; water / 2 h / -2 - 2 °C
4: lithium carbonate; lithium bromide / N,N-dimethyl-formamide / 3 h / 100 - 105 °C
View Scheme
17α-(3-hydroxypropyl)-17β-hydroxy-4-androsten-3-one
55542-27-3

17α-(3-hydroxypropyl)-17β-hydroxy-4-androsten-3-one

canrenone
976-71-6

canrenone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; potassium bromide; sodium hypochlorite; tetrabutyl-ammonium chloride / dichloromethane / 6 h / 10 - 15 °C
2: pyridine; sodium acetate; acetic acid; N-Bromosuccinimide / acetone; water / 2 h / -2 - 2 °C
3: lithium carbonate; lithium bromide / N,N-dimethyl-formamide / 3 h / 100 - 105 °C
View Scheme
SPIRONOLACTONE
52-01-7

SPIRONOLACTONE

A

3-(17β-hydroxy-3-oxo-1,4,6-androstadien-17α-yl)propionic acid γ-lactone
6785-74-6

3-(17β-hydroxy-3-oxo-1,4,6-androstadien-17α-yl)propionic acid γ-lactone

B

canrenone
976-71-6

canrenone

Conditions
ConditionsYield
With gibberella fujikuroi for 240h; Microbiological reaction;
SPIRONOLACTONE
52-01-7

SPIRONOLACTONE

A

15α-hydroxycanrenone
58551-67-0

15α-hydroxycanrenone

B

1β-hydroxycanronene

1β-hydroxycanronene

C

1α-hydroxycanrenone

1α-hydroxycanrenone

D

1-dehydro-15α-hydroxycanrenone

1-dehydro-15α-hydroxycanrenone

E

3-(3-oxo-7α-thio-17β-hydroxy-4-androsten-17α-yl)propionic acid γ-lactone
38753-76-3

3-(3-oxo-7α-thio-17β-hydroxy-4-androsten-17α-yl)propionic acid γ-lactone

F

3-(17β-hydroxy-3-oxo-1,4,6-androstadien-17α-yl)propionic acid γ-lactone
6785-74-6

3-(17β-hydroxy-3-oxo-1,4,6-androstadien-17α-yl)propionic acid γ-lactone

G

canrenone
976-71-6

canrenone

Conditions
ConditionsYield
With aspergillus alliaceus Microbiological reaction;
SPIRONOLACTONE
52-01-7

SPIRONOLACTONE

A

15α-hydroxycanrenone
58551-67-0

15α-hydroxycanrenone

B

1β-hydroxycanronene

1β-hydroxycanronene

C

1α-hydroxycanrenone

1α-hydroxycanrenone

D

1-dehydro-15α-hydroxycanrenone

1-dehydro-15α-hydroxycanrenone

E

3-(17β-hydroxy-3-oxo-1,4,6-androstadien-17α-yl)propionic acid γ-lactone
6785-74-6

3-(17β-hydroxy-3-oxo-1,4,6-androstadien-17α-yl)propionic acid γ-lactone

F

canrenone
976-71-6

canrenone

Conditions
ConditionsYield
With fusarium lini Microbiological reaction;
3-ethoxyandrosta-3,5-dien-17-one
972-46-3

3-ethoxyandrosta-3,5-dien-17-one

canrenone
976-71-6

canrenone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: lithium bromide; C30H31Cl3N3(1+)*BF4(1-); triethylamine / 1,2-dichloro-ethane / 5 h / 20 °C / Inert atmosphere; Sealed tube
2: chloranil / 1,2-dichloro-ethane; methanol; water / 1 h / 20 °C
View Scheme
C25H32O5

C25H32O5

canrenone
976-71-6

canrenone

Conditions
ConditionsYield
With acetic acid In water; toluene at 0 - 100℃; for 24h; pH=7.1; Temperature; pH-value; Autoclave; Inert atmosphere;33.1 g
C22H30O4

C22H30O4

canrenone
976-71-6

canrenone

Conditions
ConditionsYield
With methanesulfonyl chloride; triethylamine In dichloromethane at 0℃; for 4h; Temperature; Reagent/catalyst; Solvent; Inert atmosphere;8.6 g
dehydroepiandrosterone
53-43-0

dehydroepiandrosterone

canrenone
976-71-6

canrenone

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: iodine; mercury dichloride; magnesium / diethyl ether / 0.5 h / 40 °C
1.2: 2.5 h / 0 - 20 °C
2.1: lithium hexamethyldisilazane / tetrahydrofuran / 1 h / 0 °C
2.2: 2 h / 0 - 20 °C
2.3: 1 h / 0 - 20 °C
3.1: Dess-Martin periodane / dichloromethane / 4 h / 0 - 20 °C
4.1: chloranil / tert-butyl alcohol / 3 h / 80 °C
View Scheme
21,24-dinor-3β,17β-dihydroxy-chol-5-en-22-yne
156894-83-6

21,24-dinor-3β,17β-dihydroxy-chol-5-en-22-yne

canrenone
976-71-6

canrenone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: lithium hexamethyldisilazane / tetrahydrofuran / 1 h / 0 °C
1.2: 2 h / 0 - 20 °C
1.3: 1 h / 0 - 20 °C
2.1: Dess-Martin periodane / dichloromethane / 4 h / 0 - 20 °C
3.1: chloranil / tert-butyl alcohol / 3 h / 80 °C
View Scheme
3β,17β-Dihydroxy-5-androsten-17α-propanoic Acid γ-Lactone
13934-61-7

3β,17β-Dihydroxy-5-androsten-17α-propanoic Acid γ-Lactone

canrenone
976-71-6

canrenone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Dess-Martin periodane / dichloromethane / 4 h / 0 - 20 °C
2: chloranil / tert-butyl alcohol / 3 h / 80 °C
View Scheme
C22H30O3

C22H30O3

canrenone
976-71-6

canrenone

Conditions
ConditionsYield
With chloranil In tert-butyl alcohol at 80℃; for 3h;7.9 mg
formic acid
64-18-6

formic acid

canrenone
976-71-6

canrenone

A

C22H27ClO3
66175-65-3

C22H27ClO3

B

7α-Chlor-6β-(formyloxy)-17β-hydroxy-3-oxo-4,6-pregnadien-21-carbonsaeure-γ-lacton
110078-67-6

7α-Chlor-6β-(formyloxy)-17β-hydroxy-3-oxo-4,6-pregnadien-21-carbonsaeure-γ-lacton

Conditions
ConditionsYield
With tert-butylhypochlorite for 1h; Ambient temperature; Title compound not separated from byproducts;A n/a
B 91%
canrenone
976-71-6

canrenone

4-(t-butyldimethylsilyloxy)-benzyl mercaptan
245076-35-1

4-(t-butyldimethylsilyloxy)-benzyl mercaptan

3-oxo-17α-pregna-4-ene-7α-[4-(t-butyldimethylsilyloxy)-benzylthia]-21,17-carbolactone
245076-30-6

3-oxo-17α-pregna-4-ene-7α-[4-(t-butyldimethylsilyloxy)-benzylthia]-21,17-carbolactone

Conditions
ConditionsYield
With sodium at 45℃; for 0.75h; Addition;91%
canrenone
976-71-6

canrenone

11α-hydroxyl canrenone
192569-17-8

11α-hydroxyl canrenone

Conditions
ConditionsYield
With D-glucose; peptone In water90%
With D-glucose In water for 72h;80%
With D-glucose In water for 72h;80%
N,N-dimethyl(methylene)ammonium chloride
30354-18-8

N,N-dimethyl(methylene)ammonium chloride

canrenone
976-71-6

canrenone

2α-Dimethylaminomethyl-3-oxo-17α-pregna-4,6-dien-21,17-carbolacton-hydrochlorid

2α-Dimethylaminomethyl-3-oxo-17α-pregna-4,6-dien-21,17-carbolacton-hydrochlorid

Conditions
ConditionsYield
In acetonitrile for 24h; Ambient temperature;86%
canrenone
976-71-6

canrenone

[4-(2-piperidin-1-yl-ethoxy)-phenyl]-methanethiol
245076-36-2

[4-(2-piperidin-1-yl-ethoxy)-phenyl]-methanethiol

3-oxo-17α-pregna-4-ene-7α-{4-[2-(1-piperidinyl)-ethoxy]benzylthia}-21,17-carbolactone

3-oxo-17α-pregna-4-ene-7α-{4-[2-(1-piperidinyl)-ethoxy]benzylthia}-21,17-carbolactone

Conditions
ConditionsYield
With sodium at 45℃; for 1h; Addition;82%
canrenone
976-71-6

canrenone

9α,17-dihydroxy-3-oxo-17α-pregna-4,6-diene-21-carboxylic acid γ-lactone

9α,17-dihydroxy-3-oxo-17α-pregna-4,6-diene-21-carboxylic acid γ-lactone

Conditions
ConditionsYield
With Nocardia farcinica NCAIM (P)-B 001342 9α-hydroxylase; 13-ethyl-10,11α-dihydroxy-4-gonene-3,17-dione In methanol; water; N,N-dimethyl-formamide at 30℃; for 16h; Enzymatic reaction;82%
With dipotassium hydrogenphosphate; D-glucose; sodium chloride In methanol; water at 26℃; for 5 - 48h; Conversion of starting material;
With dipotassium hydrogenphosphate; D-glucose; sodium chloride In methanol; water at 26℃; for 5 - 48h; Conversion of starting material;
canrenone
976-71-6

canrenone

thioacetic acid
507-09-5

thioacetic acid

SPIRONOLACTONE
52-01-7

SPIRONOLACTONE

Conditions
ConditionsYield
Stage #1: tiolacetic acid With trifluoromethylsulfonic anhydride In tetrahydrofuran
Stage #2: canrenone In tetrahydrofuran at 20℃; for 1h;
76%
With trimethylsilyl trifluoromethanesulfonate In tetrahydrofuran at 20℃; for 3h;60%
In water at 20℃; for 2h; Michael addition;
canrenone
976-71-6

canrenone

phenylmethanethiol
100-53-8

phenylmethanethiol

3-oxo-17α-pregna-4-ene-7α-(benzylthia)-21,17-carbolactone

3-oxo-17α-pregna-4-ene-7α-(benzylthia)-21,17-carbolactone

Conditions
ConditionsYield
With sodium at 60℃; for 24h; Addition;74%
canrenone
976-71-6

canrenone

allyl-trimethyl-silane
762-72-1

allyl-trimethyl-silane

A

C25H34O3
76685-44-4

C25H34O3

B

C28H42O3Si
116506-59-3

C28H42O3Si

Conditions
ConditionsYield
titanium tetrachloride In dichloromethane at -70℃;A 73%
B 15%
1-thiopropane
107-03-9

1-thiopropane

canrenone
976-71-6

canrenone

3-oxo-17α-pregna-4-ene-7α-(propylthia)-21,17-carbolactone

3-oxo-17α-pregna-4-ene-7α-(propylthia)-21,17-carbolactone

Conditions
ConditionsYield
With sodium at 60℃; for 24h; Addition;72%
acetic anhydride
108-24-7

acetic anhydride

canrenone
976-71-6

canrenone

acetyl chloride
75-36-5

acetyl chloride

3-Acetoxy-17α-pregna-3,5,7-trien-21,17-carbolacton

3-Acetoxy-17α-pregna-3,5,7-trien-21,17-carbolacton

Conditions
ConditionsYield
With pyridine for 24h; Heating;70%
2-methylfuran
534-22-5

2-methylfuran

canrenone
976-71-6

canrenone

A

17β-hydroxy-7α-(5'-methyl-2'-furyl)-3-oxo-pregn-4-ene-21-carboxylic acid γ-lactone

17β-hydroxy-7α-(5'-methyl-2'-furyl)-3-oxo-pregn-4-ene-21-carboxylic acid γ-lactone

B

17β-hydroxy-7β-(5'-methyl-2'-furyl)-3-oxo-pregn-4-ene-21-carboxylic acid γ-lactone

17β-hydroxy-7β-(5'-methyl-2'-furyl)-3-oxo-pregn-4-ene-21-carboxylic acid γ-lactone

Conditions
ConditionsYield
With ethanol; boron trifluoride diethyl etherate In nitromethane at -19℃; for 17h;A 69.5%
B 19.8%
canrenone
976-71-6

canrenone

2α,6β,7α-Tribrom-3-oxo-17α-pregn-4-en-21,17-carbolacton

2α,6β,7α-Tribrom-3-oxo-17α-pregn-4-en-21,17-carbolacton

Conditions
ConditionsYield
With pyridinium hydrobromide perbromide In acetic acid for 1.5h; Ambient temperature;69%
methylthiol
74-93-1

methylthiol

canrenone
976-71-6

canrenone

7-Thiomethylspirolactone
38753-77-4

7-Thiomethylspirolactone

Conditions
ConditionsYield
With piperidine at 10℃;69%
With piperidine In methanol at 20℃; for 20h;
canrenone
976-71-6

canrenone

thioacetic acid
507-09-5

thioacetic acid

A

β-spironolactone
33784-05-3

β-spironolactone

B

SPIRONOLACTONE
52-01-7

SPIRONOLACTONE

Conditions
ConditionsYield
With trimethylsilyl trifluoromethanesulfonate In tetrahydrofuran for 1h; Ambient temperature; Yields of byproduct given;A n/a
B 64%
With trimethylsilyl trifluoromethanesulfonate In tetrahydrofuran for 1h; Ambient temperature; Yield given;A n/a
B 64%
Hexanethiol
111-31-9

Hexanethiol

canrenone
976-71-6

canrenone

3-oxo-17α-pregna-4-ene-7α-(hexylthia)-21,17-carbolactone

3-oxo-17α-pregna-4-ene-7α-(hexylthia)-21,17-carbolactone

Conditions
ConditionsYield
With sodium at 60℃; for 24h; Addition;62%
canrenone
976-71-6

canrenone

thiophenol
108-98-5

thiophenol

3-oxo-17α-pregna-4-ene-7α-(phenylthia)-21,17-carbolactone

3-oxo-17α-pregna-4-ene-7α-(phenylthia)-21,17-carbolactone

Conditions
ConditionsYield
With sodium at 60℃; for 24h; Addition;59%
canrenone
976-71-6

canrenone

ethanethiol
75-08-1

ethanethiol

17-hydroxy-7α-thioethyl-3-oxo-4-androstene-17α-pr0pi0nic acid, γ-lactone

17-hydroxy-7α-thioethyl-3-oxo-4-androstene-17α-pr0pi0nic acid, γ-lactone

Conditions
ConditionsYield
With sodium at 60℃; for 24h; Addition;59%
1-hexene
592-41-6

1-hexene

canrenone
976-71-6

canrenone

A

(+)-7α-hexyl-17-hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactone
1430412-93-3

(+)-7α-hexyl-17-hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactone

B

(+)-7β-hexyl-17-hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactone
1430412-96-6

(+)-7β-hexyl-17-hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactone

Conditions
ConditionsYield
Stage #1: 1-hexene With Schwartz's reagent In dichloromethane at 20℃; for 0.666667h; Inert atmosphere; Schlenk technique;
Stage #2: canrenone With chloro-trimethyl-silane; copper(I) trifluoromethanesulfonate benzene In diethyl ether; dichloromethane at 20℃; for 15h; Inert atmosphere; Schlenk technique; diastereoselective reaction;
A 59%
B 21%
Stage #1: 1-hexene With Schwartz's reagent In dichloromethane at 20℃; for 0.666667h; Inert atmosphere;
Stage #2: With C36H30CuNO2P(1+)*CF3O3S(1-) In diethyl ether; dichloromethane at 20℃; for 0.166667h; Inert atmosphere;
Stage #3: canrenone With chloro-trimethyl-silane In diethyl ether; dichloromethane at 20℃; for 15h; Inert atmosphere;
A 59%
B 21%
canrenone
976-71-6

canrenone

γ-lactone of 17α-pregna-4,6-diene-3β,17β-diol-20-carboxylic acid
67605-87-2

γ-lactone of 17α-pregna-4,6-diene-3β,17β-diol-20-carboxylic acid

Conditions
ConditionsYield
With sodium tetrahydroborate In methanol56%
canrenone
976-71-6

canrenone

6α,7α-Epoxycanrenone

6α,7α-Epoxycanrenone

Conditions
ConditionsYield
With 2,6-di-tert-butyl-4-methyl-phenol; 3-chloro-benzenecarboperoxoic acid In chloroform for 1.66667h; Heating;53%
Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View