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HANGZHOU HOLYPHARM BIOTECH CO.,LTD

Country:China (Mainland)

Year Established: 2009Business type: Other

Integral:

1. The brief introduction of Vildagliptin
Vildagliptin (CAS NO.274901-16-5)
is 2-Pyrrolidinecarbonitrile,1-[2-[(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-, (2S)- and is a white or yellow powder. Its Formula is C17H25N3O2 and Molecular Weight is 303.40. Its Synonyms may be LAF237, Jalra or XiliarxVildagliptin is an inhibitor of the enzyme dipeptidylpeptidase-4 and is used in the treatment of type 2 diabetes mellitus it may be added to metformin, a sulfonylurea, or a thiazolidinedione.

2. Other properties of Vildagliptin
Vildagliptin
 Structure:


Vildagliptin other properties: (1)ACD/LogP: -0.144 ; (2)# of Rule of 5 Violations: 0 ; (3)ACD/LogD (pH 5.5): -2.90 ; (4)ACD/LogD (pH 7.4): -1.30 ; (5)ACD/BCF (pH 5.5): 1.00 ; (6)ACD/BCF (pH 7.4): 1.00 ; (7)ACD/KOC (pH 5.5): 1.00 ; (8)ACD/KOC (pH 7.4): 1.41 ; (9)#H bond acceptors: 5 ; (10)#H bond donors: 2 ; (11)#Freely Rotating Bonds: 4 ; (12)Polar Surface Area: 76.36 Å2 ; (13)Index of Refraction: 1.601 ; (14)Molar Refractivity: 81.672 cm3 ; (15)Molar Volume: 238.325 cm3 ; (16)Polarizability: 32.377 10-24 cm3 ; (17)Surface Tension: 60.8499984741211 dyne/cm ; (18)Density: 1.273 g/cm3 ; (19)Flash Point: 275.097 °C ; (20)Enthalpy of Vaporization: 92.797 kJ/mol ; (21)Boiling Point: 531.261 °C at 760 mmHg.

3. Vildagliptin Manufacturers and Suppliers
Vildagliptin Manufacturers and Suppliers
are the main force of vildagliptin. They survive on vildagliptin and are scattering in all over the world. Top quality is their purpose. Just like HANGZHOU HOLYPHARM BIOTECH CO.,LTD, they have already developed with vildagliptin thousands of years. Most of them may be professional supplier of active pharmaceutical ingredients and intermediates. Few of them are specialized in contract R&D and custom manufacturing. Hence, when you are seeking for cooperation, please take China Vildagliptin Manufacturers and Suppliers into consideration.

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