(R)-(+)-9-(2-Hydroxypropyl)adenine supplier

Name
(R)-(+)-9-(2-Hydroxypropyl)adenine
EINECS 604-188-0
CAS No. 14047-28-0
Article Data37
CAS DataBase
Density 1.57 g/cm³
Solubility
Melting Point 193 °C
Formula C₈H₁₁N₅O
Boiling Point 457.7 °C at 760 mmHg
Molecular Weight 193.208
Flash Point 230.6 °C
Transport Information
Appearance
Safety
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms 9H-Purine-9-ethanol,6-amino-a-methyl-, (R)-;9H-Purine-9-ethanol, 6-amino-a-methyl-, D- (8CI);(R)-9-(2-Hydroxypropyl)adenine;9-[(2R)-2-Hydroxypropyl]adenine;D-(-)-9-(2-Hydroxypropyl)adenine;
PSA 89.85000
LogP 0.37050

Synthetic route

: (R)-6-acetyl-9-(2-hydroxypropyl)adenine

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

Conditions

Conditions	Yield
With sodium hydroxide In water at 93℃; for 2h; Temperature;	97.7%

: 180587-74-0
(R)-1-(6-chloro-9H-purin-9-yl) propan-2-ol

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

Conditions

Conditions	Yield
With ammonium hydroxide In 1,4-dioxane at 100 - 110℃; Sealed tube; Large scale;	96.3%
With ammonia at 65℃;	91%
With monomethanolamine In water at 0 - 60℃; for 48h;	76%

: (Z)-6-amino-9-(prop-1-en-1-yl)-9H-purine

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

Conditions

Conditions	Yield
With D-tartaric acid; 3-chloro-benzenecarboperoxoic acid In dichloromethane at 0℃; Concentration; Reagent/catalyst; Temperature;	95.4%

: 4121-40-8
9-propenyladenine

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

Conditions

Conditions	Yield
With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; (S)-(1,1'-binaphthalene)-2,2'-diylbis(diphenylphosphine) In dichloromethane at 15℃; for 5h; Temperature; Concentration;	94.7%

: 852954-49-5
(R)-5-amino-1-(2-hydroxypropyl)-1H-imidazole-4-carbonitrile

: 3473-63-0
formamidine acetic acid

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

Conditions

Conditions	Yield
With barium hydroxide monohydrate In N,N-dimethyl-formamide for 16h; Solvent; Concentration; Heating;	93%

: 66224-66-6, 66224-67-7, 66224-68-8, 66224-69-9, 134434-48-3, 134434-49-4, 134454-76-5, 134461-75-9
adenine

: 16606-55-6
(R)-1,2-propylene carbonate

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

Conditions

Conditions	Yield
With sodium hydroxide In N,N-dimethyl-formamide at 145℃; Temperature; Large scale;	89.5%
With sodium hydroxide In N,N-dimethyl-formamide at 90 - 140℃; for 12h; Inert atmosphere;	87%
With sodium hydroxide In N,N-dimethyl-formamide at 130 - 140℃; for 12h; Inert atmosphere;	87%

: 160616-02-4
(R)-9-<2-(2-tetrahydropyranyloxy)propyl>adenine

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

Conditions

Conditions	Yield
With sulfuric acid Ambient temperature;	85%

: 73-24-5
7H-purin-6-ylamine

: 16606-55-6
(R)-1,2-propylene carbonate

A: (R)-3-(2′-hydroxyprop-1-yl)adenine

B: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

Conditions

Conditions	Yield
With sodium hydroxide In N,N-dimethyl-formamide for 8h; Reflux;	A 8% B 80%

...Expand

: 66224-66-6, 66224-67-7, 66224-68-8, 66224-69-9, 134434-48-3, 134434-49-4, 134454-76-5, 134461-75-9
adenine

: 15448-47-2
(R)-propylene oxide

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

Conditions

Conditions	Yield
With sodium carbonate In N,N-dimethyl-formamide at 95℃; for 6h; Reagent/catalyst; Temperature;	69%

: 105970-02-3
1-(6-amino-9H-purin-9-yl)propan-2-one

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

Conditions

Conditions	Yield
With dichloro(benzene)ruthenium(II) dimer; sodium formate; (R)-α,α-diphenylprolinol In acetonitrile at 20 - 30℃; for 48h; enantioselective reaction;	64%

: 17435-30-2
(R)-1-(5-Amino-6-chloro-pyrimidin-4-ylamino)-propan-2-ol

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 86 percent / conc. HCl / Ambient temperature 2: 91 percent / NH3 / 65 °C View Scheme

: 66224-66-6, 66224-67-7, 66224-68-8, 66224-69-9, 134434-48-3, 134434-49-4, 134454-76-5, 134461-75-9
adenine

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: pyridine; dmap / N,N-dimethyl-formamide / 10 h / 5 - 85 °C 2.1: 4 h / 130 °C 2.2: 2 h / 20 °C / pH 9 / Cooling 3.1: sodium hydroxide / water / 2 h / 93 °C View Scheme

: 66224-66-6, 66224-67-7, 66224-68-8, 66224-69-9, 134434-48-3, 134434-49-4, 134454-76-5, 134461-75-9
adenine

: 16606-55-6
(R)-1,2-propylene carbonate

A: C8H11N5O

B: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

Conditions

Conditions	Yield
Stage #1: adenine With sodium hydroxide In N,N-dimethyl-formamide at 20℃; for 0.333333h; Stage #2: (R)-1,2-propylene carbonate at 120 - 130℃; for 16h;	A 97.9 %Chromat. B 92.9 %Chromat.

...Expand

: 73-24-5
7H-purin-6-ylamine

: 15448-47-2
(R)-propylene oxide

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

Conditions

Conditions	Yield
Stage #1: 7H-purin-6-ylamine With sodium hydroxide In water at 100 - 110℃; for 5h; Stage #2: (R)-propylene oxide With ammonium chloride In water at 25℃; Reagent/catalyst; Solvent; Temperature;	5.5 g

: 87-42-3
6-chloropurine

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: potassium carbonate / N,N-dimethyl-formamide / 0.17 h / Cooling with ice 1.2: 1 h / Cooling with ice 2.1: ruthenium; D-Prolin; sodium formate / acetonitrile / 24 h / 20 °C 3.1: monomethanolamine / water / 48 h / 0 - 60 °C View Scheme

: 4121-40-8
9-propenyladenine

A: 14047-27-9
(S)-1-(6-amino-9H-purin-9-yl) propan-2-ol

B: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

Conditions

Conditions	Yield
With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; (R)-2,2'-bis(diphenylphosphanyl)-1,1'-binaphthyl In dichloromethane at 25℃; for 5h; Temperature; Concentration; Overall yield = 43.8 %; Overall yield = 4.2 g;

: 6034-68-0
N6-acetyladenine

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: formic acid ethyl ester / 7 h / Reflux 2: sodium hydroxide / water / 2 h / 70 °C 3: lithium ethoxide / tetrahydrofuran; ethanol / 0.5 h / 20 °C 4: (S)-(1,1'-binaphthalene)-2,2'-diylbis(diphenylphosphine); 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / dichloromethane / 5 h / 15 °C View Scheme

: 6034-68-0
N6-acetyladenine

A: 14047-27-9
(S)-1-(6-amino-9H-purin-9-yl) propan-2-ol

B: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: formic acid ethyl ester / 7 h / Reflux 2: sodium hydroxide / water / 2 h / 70 °C 3: lithium ethoxide / tetrahydrofuran; ethanol / 0.5 h / 20 °C 4: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; (R)-2,2'-bis(diphenylphosphanyl)-1,1'-binaphthyl / dichloromethane / 5 h / 25 °C View Scheme

: C8H7N5O2

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: sodium hydroxide / water / 2 h / 70 °C 2: lithium ethoxide / tetrahydrofuran; ethanol / 0.5 h / 20 °C 3: (S)-(1,1'-binaphthalene)-2,2'-diylbis(diphenylphosphine); 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / dichloromethane / 5 h / 15 °C View Scheme

: C8H7N5O2

A: 14047-27-9
(S)-1-(6-amino-9H-purin-9-yl) propan-2-ol

B: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: sodium hydroxide / water / 2 h / 70 °C 2: lithium ethoxide / tetrahydrofuran; ethanol / 0.5 h / 20 °C 3: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; (R)-2,2'-bis(diphenylphosphanyl)-1,1'-binaphthyl / dichloromethane / 5 h / 25 °C View Scheme

: 9-formyladenine

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: lithium ethoxide / tetrahydrofuran; ethanol / 0.5 h / 20 °C 2: (S)-(1,1'-binaphthalene)-2,2'-diylbis(diphenylphosphine); 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / dichloromethane / 5 h / 15 °C View Scheme

: C8H11ClN4O2

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: hydrogenchloride; trimethyl orthoformate / N,N-dimethyl-formamide; water / 20 - 30 °C 2: ammonium hydroxide / 1,4-dioxane / 100 - 110 °C / Sealed tube; Large scale View Scheme

: 73-24-5
7H-purin-6-ylamine

: 16606-55-6
(R)-1,2-propylene carbonate

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

Conditions

Conditions	Yield
With sodium hydroxide In N,N-dimethyl-formamide at 125 - 138℃;

: 5-amino-1-(2-hydroxypropyl)-1H-imidazole-4-carbonitrile

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: barium hydroxide monohydrate / acetonitrile; water / 2 h / 25 °C 2: barium hydroxide monohydrate / N,N-dimethyl-formamide / 16 h / Heating View Scheme

: 35717-98-7
bis(2-propyl)-p-toluenesulfonyloxymethylphosphonate

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

: 160616-04-6
bis(2-propyl) (R)-9-(2-phosphonomethoxypropyl)adenine

Conditions

Conditions	Yield
With magnesium 2-methylpropan-2-olate In water; N,N-dimethyl-formamide at -15 - 20℃; for 44h; Inert atmosphere;	91%
With magnesium 2-methylpropan-2-olate In water; N,N-dimethyl-formamide at -15 - 20℃; for 44h; Inert atmosphere;

: 31618-90-3
diethyl (p-toluenesulfonyloxymethane)phosphonate

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

: 147127-19-3
(S)-9-(2-phosphonylmethoxypropyl)adenine

Conditions

Conditions	Yield
Stage #1: (R)-9-(2-hydroxypropyl)adenine With bis(isopropoxy) magnesium In N,N-dimethyl-formamide at 65℃; for 1h; Inert atmosphere; Stage #2: diethyl (p-toluenesulfonyloxymethane)phosphonate In N,N-dimethyl-formamide at 45 - 55℃; for 10h; Stage #3: With hydrogenchloride In water at 90℃; for 10h;	88%

: 31618-90-3
diethyl (p-toluenesulfonyloxymethane)phosphonate

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

: 180587-75-1
(R)-diethyl (((1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate

Conditions

Conditions	Yield
With magnesium 2-methylpropan-2-olate In N,N-dimethyl-formamide at 80℃; for 5h; Solvent;	85%
With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃;	44%
Stage #1: (R)-9-(2-hydroxypropyl)adenine With sodium t-butanolate In N,N-dimethyl-formamide at 20℃; for 1h; Stage #2: diethyl (p-toluenesulfonyloxymethane)phosphonate In N,N-dimethyl-formamide for 64h;	29%

: 161760-09-4
{[(4-methylbenzenesulfonyl)oxy]methyl}phosphonic acid

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

A: C9H14N5O4P

B: 147127-20-6
tenofovir

Conditions

Conditions	Yield
In 1-methyl-pyrrolidin-2-one at 0 - 20℃; Solvent; Reagent/catalyst; Temperature; Inert atmosphere; Molecular sieve;	A 12% B 82%

...Expand

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

: 147127-20-6
tenofovir

: C17H23N10O4P

Conditions

Conditions	Yield
With dmap; triethylamine; dicyclohexyl-carbodiimide In N,N-dimethyl-formamide at 90℃; Inert atmosphere;	77.8%
With dmap; triethylamine; dicyclohexyl-carbodiimide In N,N-dimethyl-formamide at 90℃; Inert atmosphere;	55%

: (di-tert-butoxyphosphoryl)methyl methanesulfonate

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

: 147127-20-6
tenofovir

Conditions

Conditions	Yield
Stage #1: (R)-9-(2-hydroxypropyl)adenine With magnesium 2-methylpropan-2-olate In N,N-dimethyl acetamide at 90℃; for 0.5h; Schlenk technique; Inert atmosphere; Stage #2: (di-tert-butoxyphosphoryl)methyl methanesulfonate In N,N-dimethyl acetamide at 90℃; for 23h; Schlenk technique; Inert atmosphere; Stage #3: With sulfuric acid at 60℃; Reagent/catalyst; Schlenk technique; Inert atmosphere;	72%

: 161760-09-4
{[(4-methylbenzenesulfonyl)oxy]methyl}phosphonic acid

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

A: C10H17N5O7P2

B: 147127-20-6
tenofovir

Conditions

Conditions	Yield
With magnesium chloride In 1-methyl-pyrrolidin-2-one at -20 - 20℃; Inert atmosphere;	A 6% B 69%

...Expand

: (di-tert-butoxyphosphoryl)methyl 4-methylbenzenesulfonate

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

: 147127-20-6
tenofovir

Conditions

Conditions	Yield
Stage #1: (R)-9-(2-hydroxypropyl)adenine With magnesium 2-methylpropan-2-olate In N,N-dimethyl-formamide at 80℃; Schlenk technique; Inert atmosphere; Stage #2: (di-tert-butoxyphosphoryl)methyl 4-methylbenzenesulfonate In N,N-dimethyl-formamide at 80℃; for 23h; Schlenk technique; Inert atmosphere; Stage #3: With sulfuric acid at 60℃; Schlenk technique; Inert atmosphere;	68%

: 161760-09-4
{[(4-methylbenzenesulfonyl)oxy]methyl}phosphonic acid

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

A: C10H17N5O7P2

B: C9H14N5O4P

C: 147127-20-6
tenofovir

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 20℃; Reagent/catalyst; Solvent; Temperature; Inert atmosphere;	A 8% B 11% C 64%

...Expand

: 31618-90-3
diethyl (p-toluenesulfonyloxymethane)phosphonate

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

: 147127-20-6
tenofovir

Conditions

Conditions	Yield
With bis(isopropoxy) magnesium In N,N-dimethyl-formamide at 45 - 65℃; for 11h; Autoclave; Inert atmosphere; Large scale;	59.2%
Stage #1: diethyl (p-toluenesulfonyloxymethane)phosphonate; (R)-9-(2-hydroxypropyl)adenine With magnesium 2-methylpropan-2-olate In 1-methyl-pyrrolidin-2-one; toluene at 25 - 75℃; for 6h; Stage #2: With water; acetic acid In 1-methyl-pyrrolidin-2-one; water; acetic acid; toluene for 1h; Stage #3: With hydrogen bromide In 1-methyl-pyrrolidin-2-one; water; toluene at 90 - 95℃;
Stage #1: (R)-9-(2-hydroxypropyl)adenine With magnesium 2-methylpropan-2-olate In N,N-dimethyl-formamide at 20 - 35℃; for 0.5h; Stage #2: diethyl (p-toluenesulfonyloxymethane)phosphonate In N,N-dimethyl-formamide at 75 - 80℃; for 2h; Stage #3: With hydrogenchloride In N,N-dimethyl-formamide at 0 - 95℃; for 9h; Temperature; Reagent/catalyst;	82 g
With trimethylsilyl bromide; water; sodium hydroxide In dichloromethane at 0 - 5℃; for 3h; pH=2.5 - 3;
Stage #1: diethyl (p-toluenesulfonyloxymethane)phosphonate; (R)-9-(2-hydroxypropyl)adenine With alumina-supported potassium hydroxide In N,N-dimethyl-formamide at 40 - 130℃; for 18h; Stage #2: With water at 100 - 105℃; for 18h; Reagent/catalyst; Temperature; Solvent;

: 62921-74-8
2-(2-(2-methoxyethoxy)ethoxy)ethyl p-toluenesulfonate

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

: C15H25N5O4

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 100℃; for 7h;	49.4%

: 98-88-4
benzoyl chloride

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

: 160616-03-5
(R)-9-(2-hydroxypropyl)-N6-benzoyladenine

Conditions

Conditions	Yield
With chloro-trimethyl-silane 1) pyridine, room temperature, 1 h; 2) pyridine, room temperature, 2 h; Yield given. Multistep reaction;

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

: 919512-64-4
(R)-9-[2-(phosphanylmethoxy)propyl]adenine

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: sodium tert-butoxide / dimethylformamide / 1 h / 20 °C 1.2: 740 mg / dimethylformamide / 64 h / 20 °C 2.1: 65 percent / TMSCl; LiAlH4 / tetrahydrofuran / 2 h / 20 °C View Scheme

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

: 919512-65-5
({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphinic acid

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: sodium tert-butoxide / dimethylformamide / 1 h / 20 °C 1.2: 740 mg / dimethylformamide / 64 h / 20 °C 2.1: 65 percent / TMSCl; LiAlH4 / tetrahydrofuran / 2 h / 20 °C 3.1: 100 percent / aq. H2O2 / tetrahydrofuran / 1 h / 20 °C View Scheme

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

: C15H30N5O3PSi2

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1.1: sodium tert-butoxide / dimethylformamide / 1 h / 20 °C 1.2: 740 mg / dimethylformamide / 64 h / 20 °C 2.1: 65 percent / TMSCl; LiAlH4 / tetrahydrofuran / 2 h / 20 °C 3.1: 100 percent / aq. H2O2 / tetrahydrofuran / 1 h / 20 °C 4.1: tetrahydrofuran / 1 h / 20 °C View Scheme

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

: 147127-20-6
tenofovir

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: LiOt-Bu / dimethylformamide; tetrahydrofuran / 1 h / 30 - 35 °C 2: 1.) bromotrimethylsilane, 2.) NaOH / 1.) acetonitrile, reflux, 2.) H2O, pH 3 View Scheme
Multi-step reaction with 2 steps 1: 44 percent / NaH / dimethylformamide / 0 - 20 °C 2: 1.) TMSBr, 2.) H2O / 1.) MeCN, RT, 2.) acetone, 4 deg C View Scheme
Multi-step reaction with 4 steps 1: 1.) chlorotrimethylsilane / 1) pyridine, room temperature, 1 h; 2) pyridine, room temperature, 2 h 2: sodium hydride / dimethylformamide / 48 h / Ambient temperature 3: sodium methoxide / dimethylformamide / Ambient temperature 4: 47 percent / bromotrimethylsilane / acetonitrile / Ambient temperature View Scheme

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

: 160616-04-6
bis(2-propyl) (R)-9-(2-phosphonomethoxypropyl)adenine

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 1.) chlorotrimethylsilane / 1) pyridine, room temperature, 1 h; 2) pyridine, room temperature, 2 h 2: sodium hydride / dimethylformamide / 48 h / Ambient temperature 3: sodium methoxide / dimethylformamide / Ambient temperature View Scheme

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

: 627510-49-0
[(R)-2-(6-Benzoylamino-purin-9-yl)-1-methyl-ethoxymethyl]-phosphonic acid diisopropyl ester

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 1.) chlorotrimethylsilane / 1) pyridine, room temperature, 1 h; 2) pyridine, room temperature, 2 h 2: sodium hydride / dimethylformamide / 48 h / Ambient temperature View Scheme

: 14047-28-0
(R)-9-(2-hydroxypropyl)adenine

A: 1244022-55-6
C15H24N5O8P

B: 1244022-53-4
C20H32N5O11P

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: magnesium 2-methylpropan-2-olate / 1-methyl-pyrrolidin-2-one / 70 - 74 °C 2.1: chloro-trimethyl-silane; sodium bromide / 1-methyl-pyrrolidin-2-one / 0 - 75 °C 3.1: triethylamine / 1-methyl-pyrrolidin-2-one / 45 °C 3.2: 5.5 h / 45 - 50 °C View Scheme

(R)-(+)-9-(2-Hydroxypropyl)adenine Chemical Properties

Product Name: (R)-(+)-9-(2-Hydroxypropyl)adenine (CAS NO.14047-28-0)

Molecular Formula: C₈H₁₁N₅O
Molecular Weight: 193.21g/mol
Mol File: 14047-28-0.mol
Melting Point: 193 °C
Boiling point: 457.7 °C at 760 mmHg
Flash Point: 230.6 °C
Density: 1.57 g/cm³
Surface Tension: 68.5 dyne/cm
Enthalpy of Vaporization: 75.64 kJ/mol
Vapour Pressure: 3.6E-09 mmHg at 25°C
Product Categories: Chiral Reagents; Bases & Related Reagents; Nucleotides

(R)-(+)-9-(2-Hydroxypropyl)adenine Specification

(R)-(+)-9-(2-Hydroxypropyl)adenine , its CAS NO. is 14047-28-0, the synonyms are R-9-(2-hydroxypropyl) adenine, 9-HPA ; (R)-(+)-9-(2-Hydroxypropyl)adenine ; 6-Amino-alpha-methyl-9H-purine-9-ethanol ; D-(-)-9-(2-Hydroxypropyl)adenine .

Product Name

(R)-(+)-9-(2-Hydroxypropyl)adenine

Synthetic route

(R)-(+)-9-(2-Hydroxypropyl)adenine Chemical Properties

(R)-(+)-9-(2-Hydroxypropyl)adenine Specification

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