1,1,1,3,3,3-Hexafluoroisopropyl acrylate supplier

Name
1,1,1,3,3,3-Hexafluoroisopropyl acrylate
EINECS 218-479-1
CAS No. 2160-89-6
Article Data2
CAS DataBase
Density 1.394 g/cm³
Solubility Insoluble
Melting Point
Formula C₆H₄F₆O₂
Boiling Point 110.3 °C at 760 mmHg
Molecular Weight 222.087
Flash Point 10 °C
Transport Information
Appearance clear colorless liquid
Safety 26-28-61-37/39-16
Risk Codes 36/37/38-51/53-11
Molecular Structure
Hazard Symbols Xi,N,F
Synonyms Acrylicacid, 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ester (7CI,8CI);Ethanol,2,2,2-trifluoro-1-(trifluoromethyl)-, acrylate (8CI);1-Trifluoromethyl-2,2,2-trifluoroethyl acrylate;HFIPA;Hexafluoroisopropylacrylate;
PSA 26.30000
LogP 2.20880

Synthetic route

: 920-66-1
1,1,1,3',3',3'-hexafluoro-propanol

: 814-68-6
acryloyl chloride

: 2160-89-6
1,1,1,3,3,3-hexafluoroisopropyl acrylate

Conditions

Conditions	Yield
With scandium tris(trifluoromethanesulfonate) at 20℃; for 20.0833h;

: 2160-89-6
1,1,1,3,3,3-hexafluoroisopropyl acrylate

: (E)-(pent-3-en-1-yn-1-yl)cyclohexane

: 1,1,1,3,3,3-hexafluoropropan-2-yl (S,E)-3-cyclohexyl-2-(prop-1-en-1-yl) cyclobut-2-ene-1-carboxylate

Conditions

Conditions	Yield
With C27H34Br2CoNOP; sodium tetrakis[(3,5-di-trifluoromethyl)phenyl]borate; zinc In toluene at 23℃; for 15h; Inert atmosphere; Glovebox; Sealed tube; enantioselective reaction;	99%

: 2160-89-6
1,1,1,3,3,3-hexafluoroisopropyl acrylate

: (E)-(pent-3-en-1-yn-1-yl)cyclohexane

: 1,1,1,3,3,3-hexafluoropropan-2-yl (E)-3-cyclohexyl-2-(prop-1-en-1-yl) cyclobut-2-ene-1-carboxylate

Conditions

Conditions	Yield
With C21H18Br2CoNOP; sodium tetrakis[(3,5-di-trifluoromethyl)phenyl]borate; zinc In toluene at 23℃; Inert atmosphere; Glovebox; Sealed tube; regioselective reaction;	99%

: 2160-89-6
1,1,1,3,3,3-hexafluoroisopropyl acrylate

: C12H16OS

: C18H20F6O3S

Conditions

Conditions	Yield
With 3,6‐di‐tert‐butyl‐9‐mesityl‐10‐phenylacridin‐10‐ium tetrafluoroborate; sodium 2,2,2-trifluoroacetate In methanol; dichloromethane at 30℃; Irradiation;	98%

: 591-50-4
iodobenzene

: 2160-89-6
1,1,1,3,3,3-hexafluoroisopropyl acrylate

: (E)-3-Phenyl-acrylic acid 2,2,2-trifluoro-1-trifluoromethyl-ethyl ester

Conditions

Conditions	Yield
With PdAS-V; triethylamine In toluene at 100℃; for 5h; Heck reaction;	95%
With triethylamine; poly{bis[(N-iPr-acrylamide)5-co-((4-vinylphenyl)PPh2)]PdCl2} In toluene at 100℃; for 5h; Heck reaction;	95%

: 2160-89-6
1,1,1,3,3,3-hexafluoroisopropyl acrylate

: 606123-24-4
N-(o-bromobenzyl)-6-pent-4-enylpiperidin-2-one

: 606123-37-9
1,1,1,3,3,3-hexafluoroisopropyl (E)-6-[1-(2-bromobenzyl)-6-oxopiperidin-2-yl]hex-2-enoate

Conditions

Conditions	Yield
Grubbs catalyst first generation In dichloromethane at 20℃; for 12h;	92%

: 15980-15-1
1,4-Oxathiane

: 2160-89-6
1,1,1,3,3,3-hexafluoroisopropyl acrylate

: C10H12F6O3S

Conditions

Conditions	Yield
With 3,6‐di‐tert‐butyl‐9‐mesityl‐10‐phenylacridin‐10‐ium tetrafluoroborate; sodium 2,2,2-trifluoroacetate In methanol; dichloromethane at 30℃; Irradiation;	91%

: 2160-89-6
1,1,1,3,3,3-hexafluoroisopropyl acrylate

: 100-52-7
benzaldehyde

: 253197-70-5
1,1,1,3,3,3-hexafluoropropan-2-yl (R)-3-hydroxy-2-methylene-3-phenylpropanoate

Conditions

Conditions	Yield
With 4-(3-ethyl-4-oxa-1-azatricyclo[4,4,0,0(3,8)]dec-5-yl)quinolin-6-ol In tetrahydrofuran; N,N-dimethyl-formamide at -55℃; for 24h; Morita-Baylis-Hillman Alkylation; enantioselective reaction;	90%
Stage #1: benzaldehyde With 4-[(5S)-3-ethyl-4-oxa-1-azatricyclo[4.4.0.03,8]decan-5-yl]quinolin-6-yl (2,2,2-trichloroacetyl)carbamate In N,N-dimethyl-formamide at 20℃; for 0.166667h; Morita-Baylis-Hillman reaction; Molecular sieve; Stage #2: 1,1,1,3,3,3-hexafluoroisopropyl acrylate In N,N-dimethyl-formamide at -55℃; for 3h; Morita-Baylis-Hillman reaction; optical yield given as %ee; enantioselective reaction;	83%
With 4-(3-ethyl-4-oxa-1-azatricyclo[4,4,0,0(3,8)]dec-5-yl)quinolin-6-ol In N,N-dimethyl-formamide at -55℃; for 48h; Baylis-Hillman reaction;	75%
With (3R,8R,9S)-10,11-dihydro-3,9-epoxy-6'-hydroxy-cinchonane In N,N-dimethyl-formamide at -55℃; for 48h; Baylis-Hillman reaction;	75%

: 29683-23-6
tetrahydrothiopyran-4-ol

: 2160-89-6
1,1,1,3,3,3-hexafluoroisopropyl acrylate

: C11H14F6O3S

Conditions

Conditions	Yield
With 3,6‐di‐tert‐butyl‐9‐mesityl‐10‐phenylacridin‐10‐ium tetrafluoroborate; sodium 2,2,2-trifluoroacetate In methanol; dichloromethane at 30℃; Irradiation;	90%

: 2160-89-6
1,1,1,3,3,3-hexafluoroisopropyl acrylate

: 96157-01-6
tert-Butyl-((8R,9S,13S,14S)-3-methoxy-13-methyl-7,8,9,11,12,13,14,15-octahydro-6H-cyclopenta[a]phenanthren-17-yloxy)-dimethyl-silane

A: (4bS,6aS,6bR,7R,8aS,9aS,9bR)-6b-(tert-Butyl-dimethyl-silanyloxy)-2-methoxy-6a-methyl-5,6,6a,6b,7,8,8a,9,9a,9b,10,11-dodecahydro-4bH-cyclobuta[3,4]cyclopenta[1,2-a]phenanthrene-7-carboxylic acid 2,2,2-trifluoro-1-trifluoromethyl-ethyl ester

B: (4bS,6aS,6bR,7S,8aS,9aS,9bR)-6b-(tert-Butyl-dimethyl-silanyloxy)-2-methoxy-6a-methyl-5,6,6a,6b,7,8,8a,9,9a,9b,10,11-dodecahydro-4bH-cyclobuta[3,4]cyclopenta[1,2-a]phenanthrene-7-carboxylic acid 2,2,2-trifluoro-1-trifluoromethyl-ethyl ester

Conditions

Conditions	Yield
With ethylaluminum dichloride In dichloromethane at -60℃; for 0.166667h; Temperature; Inert atmosphere; Overall yield = 86 %; diastereoselective reaction;	A n/a B 89%
With ethylaluminum dichloride In dichloromethane at -78℃; for 4h; Title compound not separated from byproducts;

...Expand

: 2160-89-6
1,1,1,3,3,3-hexafluoroisopropyl acrylate

: 96157-01-6
tert-Butyl-((8R,9S,13S,14S)-3-methoxy-13-methyl-7,8,9,11,12,13,14,15-octahydro-6H-cyclopenta[a]phenanthren-17-yloxy)-dimethyl-silane

: (4bS,6aS,6bR,7S,8aS,9aS,9bR)-6b-(tert-Butyl-dimethyl-silanyloxy)-2-methoxy-6a-methyl-5,6,6a,6b,7,8,8a,9,9a,9b,10,11-dodecahydro-4bH-cyclobuta[3,4]cyclopenta[1,2-a]phenanthrene-7-carboxylic acid 2,2,2-trifluoro-1-trifluoromethyl-ethyl ester

Conditions

Conditions	Yield
With ethylaluminum dichloride In dichloromethane at -40℃; for 0.166667h; Temperature; Inert atmosphere; diastereoselective reaction;	89%
Multi-step reaction with 2 steps 1: ethylaluminum dichloride / dichloromethane / 0.17 h / -60 °C / Inert atmosphere 2: ethylaluminum dichloride / dichloromethane / 0.17 h / 20 °C / Inert atmosphere View Scheme
Multi-step reaction with 2 steps 1: ethylaluminum dichloride / dichloromethane / 0.17 h / -78 °C / Inert atmosphere 2: ethylaluminum dichloride / dichloromethane / 0.17 h / 20 °C / Inert atmosphere View Scheme

: 2160-89-6
1,1,1,3,3,3-hexafluoroisopropyl acrylate

: 264279-67-6
3,3-diethyl-5,5-dimethylmorpholin-2-one

: C16H21F6NO4

Conditions

Conditions	Yield
With silver(I) acetate; palladium diacetate at 60℃;	89%

: 2160-89-6
1,1,1,3,3,3-hexafluoroisopropyl acrylate

: 1-(((dimethyl(oxo)- λ6-sulfanylidene)methyl)sulfonyl)-4-methylbenzene

: 1,1,1,3,3,3-hexafluoropropan-2-yl 2-(6-methyl-3-oxo-2,3-dihydro-1H-inden-1-yl)acetate

Conditions

Conditions	Yield
With silver hexafluoroantimonate; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; 1,1,1,3',3',3'-hexafluoro-propanol; sodium acetate at 100℃; for 24h; Glovebox;	88%

: 2160-89-6
1,1,1,3,3,3-hexafluoroisopropyl acrylate

: (2R,3S)-3-triethylsiloxy-2-methyl-3-phenylpropanal

: 1,1,1,3,3,3-hexafluoropropan-2-yl (3R,4S,5R)-3-hydroxy-5-triethylsiloxy-4-methyl-2-methylene-5-phenylpentanoate

Conditions

Conditions	Yield
With 4-(3-ethyl-4-oxa-1-azatricyclo[4,4,0,0(3,8)]dec-5-yl)quinolin-6-ol In tetrahydrofuran; N,N-dimethyl-formamide at -55℃; for 72h; Morita-Baylis-Hillman Alkylation;	87%

: 2160-89-6
1,1,1,3,3,3-hexafluoroisopropyl acrylate

: 555-16-8
4-nitrobenzaldehdye

: 1,1,1,3,3,3-hexafluoropropan-2-yl (R)-3-hydroxy-2-methylene-3-(4-nitrophenyl)-propanoate

Conditions

Conditions	Yield
With C33H27F6FeN2PS; sodium hydroxide In tetrahydrofuran at 25℃; for 48h; Catalytic behavior; Reagent/catalyst; Morita-Baylis-Hillman Alkylation; enantioselective reaction;	85%
Stage #1: 4-nitrobenzaldehdye With 4-[(5S)-3-ethyl-4-oxa-1-azatricyclo[4.4.0.03,8]decan-5-yl]quinolin-6-yl (2,2,2-trichloroacetyl)carbamate In N,N-dimethyl-formamide at 20℃; for 0.166667h; Morita-Baylis-Hillman reaction; Molecular sieve; Stage #2: 1,1,1,3,3,3-hexafluoroisopropyl acrylate In N,N-dimethyl-formamide at -55℃; for 2h; Morita-Baylis-Hillman reaction; optical yield given as %ee; enantioselective reaction;	63%

Yield

With C33H27F6FeN2PS; sodium hydroxide In tetrahydrofuran at 25℃; for 48h; Catalytic behavior; Reagent/catalyst; Morita-Baylis-Hillman Alkylation; enantioselective reaction;

85%

Stage #1: 4-nitrobenzaldehdye With 4-[(5S)-3-ethyl-4-oxa-1-azatricyclo[4.4.0.03,8]decan-5-yl]quinolin-6-yl (2,2,2-trichloroacetyl)carbamate In N,N-dimethyl-formamide at 20℃; for 0.166667h; Morita-Baylis-Hillman reaction; Molecular sieve;
Stage #2: 1,1,1,3,3,3-hexafluoroisopropyl acrylate In N,N-dimethyl-formamide at -55℃; for 2h; Morita-Baylis-Hillman reaction; optical yield given as %ee; enantioselective reaction;

63%

: 2160-89-6
1,1,1,3,3,3-hexafluoroisopropyl acrylate

: 96157-01-6
tert-Butyl-((8R,9S,13S,14S)-3-methoxy-13-methyl-7,8,9,11,12,13,14,15-octahydro-6H-cyclopenta[a]phenanthren-17-yloxy)-dimethyl-silane

: (4bS,6aS,6bR,7R,8aS,9aS,9bR)-6b-(tert-Butyl-dimethyl-silanyloxy)-2-methoxy-6a-methyl-5,6,6a,6b,7,8,8a,9,9a,9b,10,11-dodecahydro-4bH-cyclobuta[3,4]cyclopenta[1,2-a]phenanthrene-7-carboxylic acid 2,2,2-trifluoro-1-trifluoromethyl-ethyl ester

Conditions

Conditions	Yield
With ethylaluminum dichloride In dichloromethane at -78℃; for 0.166667h; Inert atmosphere; diastereoselective reaction;	85%

: 6946-99-2
3-hydroxypropyl benzoate

: 2160-89-6
1,1,1,3,3,3-hexafluoroisopropyl acrylate

: 2-(5-oxotetrahydrofuran-2-yl)ethyl benzoate

Conditions

Conditions	Yield
With quinuclidin-3-yl benzenesulfonate; 3,3,3',3'-tetrakis(trifluoromethyl)-1,1'(3H,3'H)-spirobi<2,1-benzoxasilole>; C36H16F16IrN4(1+)*F6P(1-) In acetonitrile at 20℃; for 14h; Glovebox; Inert atmosphere; Sealed tube; Irradiation;	85%

: 2160-89-6
1,1,1,3,3,3-hexafluoroisopropyl acrylate

: 66-99-9
β-naphthaldehyde

: 1476067-48-7
1,1,1,3,3,3-hexafluoropropan-2-yl (S)-3-hydroxy-2-methylene-3-(naphthalen-2-yl)-propanoate

Conditions

Conditions	Yield
With α-isocupreine In N,N-dimethyl-formamide at -55℃; for 48h; Morita-Baylis-Hillman Alkylation; Inert atmosphere; enantioselective reaction;	84%

: 2160-89-6
1,1,1,3,3,3-hexafluoroisopropyl acrylate

: 99-61-6
3-nitro-benzaldehyde

: C13H9F6NO5

Conditions

Conditions	Yield
With C33H27F6FeN2PS; sodium hydroxide In tetrahydrofuran at 25℃; for 48h; Morita-Baylis-Hillman Alkylation; enantioselective reaction;	84%

: 2160-89-6
1,1,1,3,3,3-hexafluoroisopropyl acrylate

: 79069-51-5
(S)-N-tert-butoxycarbonylvalinal

A: 916823-42-2
tert-butyl (3S,4S)-[5-((1,1,1,3,3,3-hexafluoropropan-2-yloxy)carbonyl)-4-hydroxy-2-methylhex-5-en-3-yl]carbamate

B: (2R,6S)-2,6-bis((S)-1-((tert-butoxycarbonyl)amino)-2-methylpropyl)-5-methylidene-1,3-dioxan-4-one

Conditions

Conditions	Yield
With 4-(3-ethyl-4-oxa-1-azatricyclo[4,4,0,0(3,8)]dec-5-yl)quinolin-6-ol In N,N-dimethyl-formamide at -55℃; for 46h;	A 83% B 3%

...Expand

: 110-01-0
thiophene

: 2160-89-6
1,1,1,3,3,3-hexafluoroisopropyl acrylate

: C10H12F6O2S

Conditions

Conditions	Yield
With 3,6‐di‐tert‐butyl‐9‐mesityl‐10‐phenylacridin‐10‐ium tetrafluoroborate; sodium 2,2,2-trifluoroacetate In methanol; dichloromethane at 30℃; Irradiation;	83%

: 1613-51-0
sulfure de pentamethylene

: 2160-89-6
1,1,1,3,3,3-hexafluoroisopropyl acrylate

: C11H14F6O2S

Conditions

Conditions	Yield
With 3,6‐di‐tert‐butyl‐9‐mesityl‐10‐phenylacridin‐10‐ium tetrafluoroborate; sodium 2,2,2-trifluoroacetate In methanol; dichloromethane at 30℃; Irradiation;	83%

: 1072-72-6
Tetrahydrothiopyran-4-one

: 2160-89-6
1,1,1,3,3,3-hexafluoroisopropyl acrylate

: C11H12F6O3S

Conditions

Conditions	Yield
With 3,6‐di‐tert‐butyl‐9‐mesityl‐10‐phenylacridin‐10‐ium tetrafluoroborate; sodium 2,2,2-trifluoroacetate In methanol; dichloromethane at 30℃; Irradiation;	83%

: 2160-89-6
1,1,1,3,3,3-hexafluoroisopropyl acrylate

: 68081-19-6
tert-butyl (cyclohept-1-en-1-yloxy)dimethylsilane

: (1RS,7SR,9RS)-1-(tert-butyldimethylsiloxy)-9-(1,1,1,3,3,3-hexafluoroisopropoxycarbonyl)bicyclo[5.2.0]nonane

Conditions

Conditions	Yield
With ethylaluminum dichloride In dichloromethane at -78℃; for 4h;	82%

: 2160-89-6
1,1,1,3,3,3-hexafluoroisopropyl acrylate

: 66-99-9
β-naphthaldehyde

: 1,1,1,3,3,3-hexafluoropropan-2-yl (R)-3-hydroxy-2-methylene-3-(naphthalen-2-yl)propanoate

Conditions

Conditions	Yield
With (3R,8R,9S)-10,11-dihydro-3,9-epoxy-6'-hydroxy-cinchonane In N,N-dimethyl-formamide at -55℃; for 58h; Baylis-Hillman reaction;	82%

: 2160-89-6
1,1,1,3,3,3-hexafluoroisopropyl acrylate

: 73183-34-3
bis(pinacol)diborane

: 1454308-52-1
1,1,1,3,3,3-hexafluoro-propan-2-yl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propanoate

Conditions

Conditions	Yield
Stage #1: bis(pinacol)diborane With copper(II) carbonate; triphenylphosphine In water at 20℃; for 0.5h; Inert atmosphere; Stage #2: 1,1,1,3,3,3-hexafluoroisopropyl acrylate In water at 27℃; for 24h; Inert atmosphere;	82%
Stage #1: bis(pinacol)diborane With copper carbonate hydroxide; triphenylphosphine In water at 20℃; for 0.5h; Inert atmosphere; Stage #2: 1,1,1,3,3,3-hexafluoroisopropyl acrylate In water at 27℃; for 24h; Inert atmosphere;	82%
Stage #1: bis(pinacol)diborane With copper(II) carbonate; triphenylphosphine In water at 20℃; for 0.5h; Inert atmosphere; Stage #2: 1,1,1,3,3,3-hexafluoroisopropyl acrylate In water at 27℃; for 24h; Inert atmosphere;	82%

: 2160-89-6
1,1,1,3,3,3-hexafluoroisopropyl acrylate

: 111-27-3
hexan-1-ol

: 104-61-0
γ-nonalactone

Conditions

Conditions	Yield
With quinuclidin-3-yl benzenesulfonate; 3,3,3',3'-tetrakis(trifluoromethyl)-1,1'(3H,3'H)-spirobi<2,1-benzoxasilole>; C36H16F16IrN4(1+)*F6P(1-) In acetonitrile at 20℃; for 14h; Glovebox; Inert atmosphere; Sealed tube; Irradiation;	82%

: 2160-89-6
1,1,1,3,3,3-hexafluoroisopropyl acrylate

: 80522-46-9
1-triisopropylsiloxy-1-cyclohexene

: (1RS,6SR,8RS)-1-(triisopropylsiloxy)-8-(1,1,1,3,3,3-hexafluoroisopropoxycarbonyl)bicyclo[4.2.0]octane

Conditions

Conditions	Yield
With ethylaluminum dichloride In dichloromethane at -78℃; for 4h;	80%

: 2160-89-6
1,1,1,3,3,3-hexafluoroisopropyl acrylate

: 16588-34-4
4-chloro-3-nitro-benzaldehyde

: C13H8ClF6NO5

Conditions

Conditions	Yield
With C33H27F6FeN2PS; sodium hydroxide In tetrahydrofuran at 25℃; for 48h; Morita-Baylis-Hillman Alkylation; enantioselective reaction;	80%

: 875282-59-0
4-(phenylthio-methyl)-piperidine-1-carboxylic acid tert-butyl ester

: 2160-89-6
1,1,1,3,3,3-hexafluoroisopropyl acrylate

: C23H29F6NO4S

Conditions

Conditions	Yield
With 3,6‐di‐tert‐butyl‐9‐mesityl‐10‐phenylacridin‐10‐ium tetrafluoroborate; sodium 2,2,2-trifluoroacetate In methanol; dichloromethane at 30℃; Irradiation;	78%

: 2160-89-6
1,1,1,3,3,3-hexafluoroisopropyl acrylate

: 58521-45-2
tert-butoxycarbonyl-L-leucinal

A: 916823-40-0
tert-butyl (3S,4S)-[2-((1,1,1,3,3,3-hexafluoropropan-2-yloxy)carbonyl)-3-hydroxy-6-methylhept-1-en-4-yl]carbamate

B: 2,6-bis((S)-1-((tert-butoxycarbonyl)amino)-3-methylbutyl)-5-methylidene-1,3-dioxan-4-one

Conditions

Conditions	Yield
With 4-(3-ethyl-4-oxa-1-azatricyclo[4,4,0,0(3,8)]dec-5-yl)quinolin-6-ol In N,N-dimethyl-formamide at -55℃; for 46h;	A 77% B 4%

...Expand

1,1,1,3,3,3-Hexafluoroisopropyl acrylate Specification

The 1,1,1,3,3,3-Hexafluoroisopropyl acrylate is an organic compound with the formula C₆H₄F₆O₂. The IUPAC name of this chemical is 1,1,1,3,3,3-hexafluoropropan-2-yl prop-2-enoate. With the CAS registry number 2160-89-6, it is also named as 2-Propenoic acid, 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ester. The product's categories are monomer;Acrylic Monomers;C6 to C7Monomers; Carbonyl Compounds; Esters; Fluorinated AcrylicsSelf Assembly&Contact Printing; Fluorine-Containing Monomers for 157 nm UV Lithography Resist PolymersPhotonic and Optical Materials;Lithography Monomers; Low Refractive Index Monomers; Waveguide Materials. Besides, it is a clear colorless liquid, which should be stored in a cold, dry place.

Physical properties about 1,1,1,3,3,3-Hexafluoroisopropyl acrylate are: (1)ACD/LogP: 1.80; (2)ACD/LogD (pH 5.5): 1.79; (3)ACD/LogD (pH 7.4): 1.79; (4)ACD/BCF (pH 5.5): 13.62; (5)ACD/BCF (pH 7.4): 13.62; (6)ACD/KOC (pH 5.5): 225.61; (7)ACD/KOC (pH 7.4): 225.61; (8)#H bond acceptors: 2; (9)#Freely Rotating Bonds: 3; (10)Polar Surface Area: 26.3 Å²; (11)Index of Refraction: 1.326; (12)Molar Refractivity: 32.21 cm³; (13)Molar Volume: 159.3 cm³; (14)Polarizability: 12.77×10^-24cm³; (15)Surface Tension: 18.2 dyne/cm; (16)Density: 1.394 g/cm³; (17)Flash Point: 10 °C; (18)Enthalpy of Vaporization: 34.9 kJ/mol; (19)Boiling Point: 110.3 °C at 760 mmHg; (20)Vapour Pressure: 23.9 mmHg at 25°C.

Uses of 1,1,1,3,3,3-Hexafluoroisopropyl acrylate: it can be used to produce -(1-hydroxy-propyl)-acrylic acid 2,2,2-trifluoro-1-trifluoromethyl-ethyl ester at temperature of -55 °C. This reaction is a kind of Addition. It will need reagent (3R,8R,9S)-10,11-dihydro-3,9-epoxy-6'-hydroxycinchonane and solvent dimethylformamide with reaction time of 4 hours. The yield is about 40%.

When you are using this chemical, please be cautious about it as the following:
It is highly flammable, and harmful by inhalation, in contact with skin and if swallowed. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Besides, this chemical is Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. When you are using it, Keep away from sources of ignition - No smoking, and wear suitable suitable protective clothing and gloves. After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer).

You can still convert the following datas into molecular structure:
(1)SMILES: FC(F)(F)C(OC(=O)\C=C)C(F)(F)F
(2)InChI: InChI=1/C6H4F6O2/c1-2-3(13)14-4(5(7,8)9)6(10,11)12/h2,4H,1H2
(3)InChIKey: MNSWITGNWZSAMC-UHFFFAOYAP
(4)Std. InChI: InChI=1S/C6H4F6O2/c1-2-3(13)14-4(5(7,8)9)6(10,11)12/h2,4H,1H2
(5)Std. InChIKey: MNSWITGNWZSAMC-UHFFFAOYSA-N

Product Name

1,1,1,3,3,3-Hexafluoroisopropyl acrylate

Synthetic route

1,1,1,3,3,3-Hexafluoroisopropyl acrylate Specification

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