1-Chlorooctadecane supplier

Name
1-Chlorooctadecane
EINECS 222-207-7
CAS No. 3386-33-2
Article Data25
CAS DataBase
Density 0.857 g/cm³
Solubility 0.03 g/L (20 °C) in water
Melting Point 20-24 °C
Formula C₁₈H₃₇Cl
Boiling Point 347.8 °C at 760 mmHg
Molecular Weight 288.945
Flash Point 151.9 °C
Transport Information UN 1593 6.1/PG 3
Appearance clear colorless to yellowish liquid after melting
Safety 26-36-45-36/37/39-23-53-36/37-24/25
Risk Codes 36/37/38-63-20/22-45-40
Molecular Structure
Hazard Symbols Xn, T, Xi
Synonyms 1-Octadecyl chloride;NSC 5543;Octadecyl chloride;n-Octadecyl chloride;
PSA 0.00000
LogP 7.48670

Synthetic route

: 112-92-5
1-octadecanol

: 3386-33-2
1-chlorooctadecane

Conditions

Conditions	Yield
With hydrogenchloride; N-n-octylalkylpyridinium chlorides; mixture of at 150℃; for 8h; Product distribution / selectivity;	99.8%
With Amberlite IRA 93 (PCl5 form) In benzene for 5h; Heating;	96%
With hydrogenchloride; trimethyloctadecylammonium chloride for 10h; Irradiation;	77%

: 2-(octadecylthio)benzonitrile

A: 2634-33-5
1,2-benzisothiazolin-3-one

B: 3386-33-2
1-chlorooctadecane

Conditions

Conditions	Yield
With water; chlorine In chlorobenzene at 20 - 65℃; for 3h;	A 93.5% B 210 g
With water; chlorine In chlorobenzene at 20 - 65℃; for 3h;

: 2-(octadecylthio)benzonitrile

A: 2634-33-5
1,2-benzisothiazolin-3-one

B: 873-32-5
2-Chlorobenzonitrile

C: 3386-33-2
1-chlorooctadecane

Conditions

Conditions	Yield
Stage #1: 2-(octadecylthio)benzonitrile With water; chlorine In chlorobenzene at 20 - 65℃; for 3h; Stage #2: With sodium hydroxide In water at 60 - 65℃; pH=9 - 10; Stage #3: With hydrogenchloride In water at 20 - 30℃; pH=3 - 4;	A 102 g B 93.5% C 210 g

...Expand

: 57-11-4
stearic acid

: 3386-33-2
1-chlorooctadecane

Conditions

Conditions	Yield
With phosgene; 4-(dimethylamino)pyridine hydrochloride at 150℃;	91%

: 51637-93-5
stearyl chloroformate

: 3386-33-2
1-chlorooctadecane

Conditions

Conditions	Yield
With hexabutylguanidinium chloride at 120℃; for 4h;	90%

: 2885-00-9
Octadecanethiol

: 3386-33-2
1-chlorooctadecane

Conditions

Conditions	Yield
With tetrachloromethane; cross-linked polymer (containing 2.50 mmol of phosphine/g) for 3h; Heating;	78%
Multi-step reaction with 2 steps 1.1: tetrabutylammomium bromide; sodium hydroxide / chlorobenzene; water / 4 h / 65 - 70 °C / Inert atmosphere 2.1: chlorine; water / chlorobenzene / 3 h / 20 - 65 °C 2.2: 60 - 65 °C / pH 9 - 10 2.3: 20 - 30 °C / pH 3 - 4 View Scheme

: 74-85-1
ethene

: 3386-33-2
1-chlorooctadecane

Conditions

Conditions	Yield
With hydrogenchloride; dibenzoyl peroxide at 100℃; under 294203 - 367754 Torr;
With hydrogenchloride; dibenzoyl peroxide at 100℃; under 294203 - 367754 Torr;

: 62008-64-4
thiocarbonic acid O-(4-chloro-phenyl) ester O-octadecyl ester

: 3386-33-2
1-chlorooctadecane

Conditions

Conditions	Yield
With pyridine; benzenesulfenyl chloride

: chlorosulfurous acid octadecyl ester

A: 3386-33-2
1-chlorooctadecane

B SO2: SO2

Conditions

Conditions	Yield
at 97℃;

: 110-86-1
pyridine

: chlorosulfurous acid octadecyl ester

A: 3386-33-2
1-chlorooctadecane

B SO2: SO2

Conditions

Conditions	Yield
at 54℃;

...Expand

: 10147-41-8
1-octadecanesulfonyl chloride

A: 3386-33-2
1-chlorooctadecane

B sulfur dioxide: sulfur dioxide

Conditions

Conditions	Yield
at 125℃; Rate constant; Pyrolysis;
at 150℃; Rate constant; Pyrolysis;
at 175℃; Rate constant; Pyrolysis;

: 593-45-3
octadecane

A: 3386-33-2
1-chlorooctadecane

B: 71662-61-8
1-chlorooctadecane

Conditions

Conditions	Yield
With tetrachloromethane; manganese(III) acetylacetonate; acetonitrile at 200℃; for 8h; Time; Sealed tube;

: 3386-33-2
1-chlorooctadecane

: 931-15-7, 931-16-8, 6850-38-0, 6982-39-4, 33092-82-9, 38898-70-3, 74111-21-0, 108267-20-5
(1R,2R)-2-aminocyclohexanol

: (1R,2R)-2-(Stearoylamino)cyclohexanol

Conditions

Conditions	Yield
	100%
	100%

: 3386-33-2
1-chlorooctadecane

: 498-63-5
2-hydroxymethylpyrrolidine

: (S)-1-Stearoyl-2-pyrrolidinemethanol

Conditions

Conditions	Yield
	100%

: 3386-33-2
1-chlorooctadecane

: 86639-52-3, 110714-48-2, 130144-34-2
7-ethyl-10-hydroxycamptothecin

: 7-ethyl-10-hydroxycamptothecin-10-stearate

Conditions

Conditions	Yield
Stage #1: 7-ethyl-10-hydroxycamptothecin With pyridine In dichloromethane for 0.333333h; Cooling with ice; Stage #2: 1-chlorooctadecane In dichloromethane at 20℃; for 12h; Reagent/catalyst; Solvent; Cooling with ice;	98.75%

: 3386-33-2
1-chlorooctadecane

: 75-86-5
2-hydroxy-2-methylpropanenitrile

: 28623-46-3
N-nonadecyl nitrile

Conditions

Conditions	Yield
Stage #1: 2-hydroxy-2-methylpropanenitrile With lithium hydroxide monohydrate In tetrahydrofuran at 50℃; for 1h; Stage #2: 1-chlorooctadecane In tetrahydrofuran	95.1%

: 3386-33-2
1-chlorooctadecane

: 117048-62-1, 117048-59-6
combrestatin A4

: (Z)-2-methoxy-5-(3,4, 5-trimethoxystyryl)phenyl stearate

Conditions

Conditions	Yield
Stage #1: combrestatin A4 With N-ethyl-N,N-diisopropylamine In dichloromethane for 0.333333h; Stage #2: 1-chlorooctadecane In dichloromethane at 0 - 20℃; for 2.25h;	94.32%

: 3386-33-2
1-chlorooctadecane

: 112-04-9
octadecyltrichlorosilane

Conditions

Conditions	Yield
With trichlorosilane; tetra-n-butylphosphonium chloride at 170℃; for 6h;	93%

: 3386-33-2
1-chlorooctadecane

: 110-18-9
N,N,N,N,-tetramethylethylenediamine

: C24H53N2(1+)*Cl(1-)

Conditions

Conditions	Yield
In methanol at 50℃; for 28h; Inert atmosphere;	91.5%

: 288-32-4
1H-imidazole

: 3386-33-2
1-chlorooctadecane

: 5709-33-1
1-octadecyl-1H-imidazole

Conditions

Conditions	Yield
With sodium hydroxide; tetraethylammonium bromide In benzene for 72h; Heating;	90%

: 3386-33-2
1-chlorooctadecane

: 5188-07-8
sodium thiomethoxide

: 40289-98-3
methyl n-octadecyl sulfide

Conditions

Conditions	Yield
In ethanol Substitution; Heating;	88%

: 3386-33-2
1-chlorooctadecane

: 75178-96-0
N-Boc-1,3-diaminopropane

: N-Boc-N’-stearoyl-1,3-diamine

Conditions

Conditions	Yield
With triethylamine In dichloromethane Inert atmosphere;	87.7%

: 3386-33-2
1-chlorooctadecane

: 6146-52-7
5-nitroindole

: 5-nitro-1-octadecyl-1H-indole

Conditions

Conditions	Yield
Stage #1: 5-nitroindole With sodium hydride In N,N-dimethyl-formamide; mineral oil at 20℃; for 0.666667h; Stage #2: 1-chlorooctadecane With sodium iodide In N,N-dimethyl-formamide; mineral oil	84.5%

: 109-83-1
(2-hydroxyethyl)(methyl)amine

: 3386-33-2
1-chlorooctadecane

: 32582-64-2
N-Octadecyl-N-methyl-β-hydroxyethylamine

Conditions

Conditions	Yield
In acetone for 20h; Heating;	83%

: 109-04-6
2-bromo-pyridine

: 3386-33-2
1-chlorooctadecane

: 1558056-00-0
2-(octadec-1-ylthio)pyridine

Conditions

Conditions	Yield
With 1,1'-bis-(diphenylphosphino)ferrocene; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; Sodium thiosulfate pentahydrate; caesium carbonate In ethylene glycol; dimethyl sulfoxide at 120℃; Schlenk technique; Inert atmosphere; Green chemistry;	82%
With 1,1'-bis-(diphenylphosphino)ferrocene; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; Sodium thiosulfate pentahydrate; caesium carbonate In ethylene glycol; dimethyl sulfoxide at 120℃; Inert atmosphere;	82%

: 3386-33-2
1-chlorooctadecane

: 1708-40-3, 4141-19-9, 4141-20-2
trans-2-phenyl-1,3-dioxan-5-ol

: 87515-26-2
trans-5-(1-octadecyloxy)-2-phenyl-1,3-dioxan

Conditions

Conditions	Yield
With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate In water; toluene at 60℃; for 15h;	81%

: 3386-33-2
1-chlorooctadecane

: 74-89-5
methylamine

: 4088-22-6
N-methyldioctadecylamine

Conditions

Conditions	Yield
With sodium hydroxide; potassium iodide In water at 120℃; for 144h;	80%

: 3386-33-2
1-chlorooctadecane

: 59-05-2
N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid

: 86669-32-1
(S)-2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid dioctadecyl ester

Conditions

Conditions	Yield
With caesium carbonate In water; dimethyl sulfoxide for 45h; Ambient temperature;	76%

: (4-(6,7-dihydroxy-4-thiaheptanoylamino)benzoyl)glutamic acid di-t-butyl ester

: 3386-33-2
1-chlorooctadecane

: (4-(6,7-bis(stearyloxy)-4-thiaheptanoylamino)benzoyl)glutamic acid di-t-butyl ester

Conditions

Conditions	Yield
With 2-(Dimethylamino)pyridine; sodium bicarbonate; triethylamine; citric acid In chloroform; water	76%

: 3386-33-2
1-chlorooctadecane

: 1-(4-ferrocenylphenyl)-3-(4-chlorobenzoyl)thiourea monohydrate

: 4-ferrocenyl-N-((4-chlorobenzoyl)carbamothioyl)-N-octadecylbenzenium chloride

Conditions

Conditions	Yield
In ethanol at 80℃; for 24h;	75%

: 3386-33-2
1-chlorooctadecane

: 1708-40-3, 4141-19-9, 4141-20-2
cis-5-hydroxyl-2-phenyl-1,3-dioxane

: 82521-21-9
cis-5-(1-octadecyloxy)-2-phenyl-1,3-dioxan

Conditions

Conditions	Yield
With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate In water; toluene at 60℃;	67%
	67%

: 75-15-0
carbon disulfide

: 3386-33-2
1-chlorooctadecane

: 1-((3R,5aS,6R,8aS,9R,10R,12aR)-3,6,9-trimethyldecahydro-3H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl)piperazine

: C38H68N2O4S2

Conditions

Conditions	Yield
Stage #1: carbon disulfide; 1-((3R,5aS,6R,8aS,9R,10R,12aR)-3,6,9-trimethyldecahydro-3H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl)piperazine With triethylamine In acetonitrile at 20℃; for 0.166667h; Stage #2: 1-chlorooctadecane In acetonitrile at 20 - 60℃; for 0.0833333h;	49.3%

...Expand

: 3386-33-2
1-chlorooctadecane

: 5149-49-5
rac-3-(benzylsulfanyl)propane-1,2-diol

: 1-Benzylsulfanyl-3-octadecyloxy-propan-2-ol

Conditions

Conditions	Yield
With sodium hydroxide; tetrabutylammomium bromide In benzene for 48h; Ambient temperature;	35%

: 3386-33-2
1-chlorooctadecane

: trans-atovaquone

: 2-octadecanoxy-3-(E-4-(para-chlorophenyl)-cyclohexyl)-1,4-naphthoquinone

Conditions

Conditions	Yield
Stage #1: trans-atovaquone With potassium carbonate In butanone for 0.5h; Reflux; Stage #2: 1-chlorooctadecane In butanone for 14h; Reflux;	26%

1-Chlorooctadecane Chemical Properties

Molecular Structure:

Molecular Formula: C₁₈H₃₇Cl
Molecular Weight: 288.9394
IUPAC Name: 1-chlorooctadecane
Synonyms of Octadecane, 1-chloro- (CAS NO.3386-33-2): AI3-28591 ; EINECS 222-207-7 ; NSC 5543 ; Octadecyl chloride ; n-Octadecyl chloride ; 1-Chlorooctadecane
CAS NO: 3386-33-2
Classification Code: Alkyl Chlorides ; Monofunctional & alpha,omega-Bifunctional Alkanes ; Monofunctional Alkanes
Melting point: 20-24 °C
Index of Refraction: 1.448
Molar Refractivity: 90.28 cm³
Molar Volume: 337 cm³
Surface Tension: 29.6 dyne/cm
Density: 0.857 g/cm³
Flash Point: 151.9 °C
Enthalpy of Vaporization: 56.87 kJ/mol
Boiling Point: 347.8 °C at 760 mmHg
Vapour Pressure: 0.000106 mmHg at 25°C

1-Chlorooctadecane Safety Profile

Hazard Codes of Octadecane, 1-chloro- (CAS NO.3386-33-2): Irritant Xi, Toxic T, Harmful Xn
Risk Statements: 36/37/38-63-20/22-45-40
R36/37/38: Irritating to eyes, respiratory system and skin.
R63: Possible risk of harm to the unborn child.
R20/22: Harmful by inhalation and if swallowed.
R45: May cause cancer.
R40: Limited evidence of a carcinogenic effect.
Safety Statements: 26-45-36/37/39-23-53-24/25
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
S23: Do not breathe vapour.
S53: Avoid exposure - obtain special instructions before use.
S24/25: Avoid contact with skin and eyes.
RIDADR: UN 1593 6.1/PG 3
WGK Germany: 3
RTECS: RG0187200
HS Code: 29031980

Product Name

1-Chlorooctadecane

Synthetic route

1-Chlorooctadecane Chemical Properties

1-Chlorooctadecane Safety Profile

Related Products

Hot Products