1-Ethylcyclohexanol supplier

Name
1-Ethylcyclohexanol
EINECS 621-537-2
CAS No. 1940-18-7
Article Data63
CAS DataBase
Density 0.919 g/cm³
Solubility
Melting Point 34.5°C
Formula C₈H₁₆O
Boiling Point 165.999 °C at 760 mmHg
Molecular Weight 128.214
Flash Point 68.17 °C
Transport Information
Appearance
Safety 26-36/37/39
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols
Synonyms 1-Ethyl-1-cyclohexanol;1-Ethyl-1-hydroxycyclohexane;NSC 25550;
PSA 20.23000
LogP 2.09160

Synthetic route

: 925-90-6
ethylmagnesium bromide

: 108-94-1
cyclohexanone

: 1940-18-7
1-ethylcyclohexanol

Conditions

Conditions	Yield
With methylaluminum bis(2,6-di-tert-butylphenoxide) In diethyl ether; toluene at -78℃; for 2h;	100%
In diethyl ether at 0 - 20℃;	90%
In diethyl ether; benzene
In diethyl ether

: 78-27-3
1-Ethynyl-1-cyclohexanol

: 1940-18-7
1-ethylcyclohexanol

Conditions

Conditions	Yield
With ethanol; lithium; nickel dichloride; poly(4-vinylbiphenyl-co-divinylbenzene) In tetrahydrofuran at 20℃; for 12h;	95%
With sodium tetrahydroborate; copper(ll) sulfate pentahydrate; cobalt(II) chloride hexahydrate In methanol at 20℃; for 0.333333h;	94%
With sodium tetrahydroborate; hydrogen; nickel dichloride In isopropyl alcohol at 60℃; under 760.051 Torr; for 8h;	92%

: 17328-74-4
2-methyl-1-oxaspiro[2.5]octane

: 1940-18-7
1-ethylcyclohexanol

Conditions

Conditions	Yield
With lithium triethylborohydride	95%

: 78-27-3
1-Ethynyl-1-cyclohexanol

A: 1940-19-8
1-vinylcyclohexanol

B: 1940-18-7
1-ethylcyclohexanol

Conditions

Conditions	Yield
With hydrogen; copper-palladium; silica gel In ethanol at 25℃; under 760 Torr; Kinetics;	A 94% B n/a
With quinoline; hydrogen; Lindlar catalyst with MnCl2 doping salt In n-heptane at 25℃; under 735 - 738 Torr; Product distribution; without doping salt;
With potassium chloride; hydrogen; nickel In methanol; water Product distribution; catodically pretreated Raney-Ni-powder; hydrogenation in presence of pyridine or hydrogensulfide; change of potential during the hydrogenation;
With hydrazine hydrate; cobalt(II) chloride; sodium hydroxide In isopropyl alcohol at 60℃; for 6h; Reagent/catalyst;
With hydrogen; dimethyl sulfoxide In ethyl acetate at 20℃; under 760.051 Torr; for 1.25h;	A 91 %Spectr. B 9 %Spectr.

: 17328-74-4
2-methyl-1-oxaspiro[2.5]octane

A: 1940-18-7
1-ethylcyclohexanol

B: 1193-81-3
rac-1-cyclohexylethanol

C: 1-(1-chlorocyclohexyl)ethanol

Conditions

Conditions	Yield
With bis(cyclopentadienyl)titanium (III) chloride; cyclohexa-1,4-diene In tetrahydrofuran Product distribution; Mechanism; Ambient temperature; other epoxides, reaction without cyclohexa-1,4-diene;	A 1.5% B 92% C 0.9%
With bis(cyclopentadienyl)titanium (III) chloride; cyclohexa-1,4-diene In tetrahydrofuran Ambient temperature;	A 1.5% B 92% C 0.9%
With bis(cyclopentadienyl)titanium (III) chloride; cyclohexa-1,4-diene In tetrahydrofuran for 0.666667h; Product distribution; Mechanism; other epoxides; other H-atom donors; var. temperature, var. time;	A 1.5% B 64% C 0.9%
With bis(cyclopentadienyl)titanium (III) chloride; cyclohexa-1,4-diene In tetrahydrofuran for 0.25h;	A n/a B 64% C 0.9%
With bis(cyclopentadienyl)titanium (III) chloride; cyclohexa-1,4-diene In tetrahydrofuran for 0.25h; Yields of byproduct given;	A n/a B n/a C 0.9%

...Expand

: 97-94-9
triethyl borane

: 108-94-1
cyclohexanone

: 1940-18-7
1-ethylcyclohexanol

Conditions

Conditions	Yield
With tetra-(n-butyl)ammonium iodide In tetrahydrofuran; N,N-dimethyl-formamide for 8h; Ambient temperature; electrolysis with Pt/Cu electrodes;	76%

: 425-75-2
trifluoromethanesulfonic acid ethyl ester

: 108-94-1
cyclohexanone

: 1940-18-7
1-ethylcyclohexanol

Conditions

Conditions	Yield
With naphthalene; lithium In tetrahydrofuran at -78 - 0℃; for 2h;	75%

: 1678-91-7
ethyl-cyclohexane

A: 4233-57-2
6-oxooctanoic acid

B: 1940-18-7
1-ethylcyclohexanol

Conditions

Conditions	Yield
With ozone In neat (no solvent) at 20℃; for 5h; UV-irradiation;	A 67% B 10%

: 108-94-1
cyclohexanone

: C15H33NO6*2C2H5BrMg

: 1940-18-7
1-ethylcyclohexanol

Conditions

Conditions	Yield
In toluene for 5h; Ambient temperature;	61%

: 1940-19-8
1-vinylcyclohexanol

: 79-10-7
acrylic acid

A: 699-61-6
1-oxaspiro[4.5]decan-2-one

B: 1940-18-7
1-ethylcyclohexanol

Conditions

Conditions	Yield
With hydrogen; platinum(IV) oxide; ruthenium In dichloromethane at 20℃; under 760.051 Torr;	A 57% B 6%

...Expand

: 599-70-2
ethyl phenyl sulfone

: 108-94-1
cyclohexanone

A: 1589-60-2
1-phenylcyclohexanol

B: 1940-18-7
1-ethylcyclohexanol

Conditions

Conditions	Yield
With naphthalene; boron trifluoride diethyl etherate; lithium In tetrahydrofuran at -78 - 20℃; for 5h;	A 11% B 32%

...Expand

: 10467-10-4
ethylmagnesium iodide

: 108-94-1
cyclohexanone

: 1940-18-7
1-ethylcyclohexanol

: 108-94-1
cyclohexanone

: ethyl magnesium (1+); iodide

: 1940-18-7
1-ethylcyclohexanol

Conditions

Conditions	Yield
analog reagiert mit 1-Methyl-cyclohexanon-(2), 1-Methyl-cyclohexanon-(3), 1-Methyl-cyclohexanon-(4) und Nopinon;

: 811-49-4
ethyllithium

: 108-94-1
cyclohexanone

: 1940-18-7
1-ethylcyclohexanol

Conditions

Conditions	Yield
In diethyl ether
With copper(l) iodide 1.) 0.5 h, -50 deg C, THF; 2.) THF, 1 h, -78 deg C; Yield given. Multistep reaction;

: 1445-98-3
1-ethyl-1-chloro-cyclohexane

A: 1453-24-3
1-ethylcyclohexene

B: 1940-18-7
1-ethylcyclohexanol

Conditions

Conditions	Yield
With water In ethanol at 30℃; Rate constant; solvolysis reaction;

: 64-67-5
diethyl sulfate

: 108-94-1
cyclohexanone

: 1940-18-7
1-ethylcyclohexanol

Conditions

Conditions	Yield
With lithium; naphthalene 1) THF, -78 deg C, 1 h, 2) THF, -78 to 20 deg C, 5 h; Yield given. Multistep reaction;
With naphthalene; lithium 1) THF, -78 deg C, 75 min, 2) THF, -78 to 20 deg C, 5 h; Yield given. Multistep reaction;

: 108-94-1
cyclohexanone

: 90334-43-3
N-Eth-(Z)-ylidene-N'-trityl-hydrazine

: 1940-18-7
1-ethylcyclohexanol

Conditions

Conditions	Yield
Yield given. Multistep reaction;

: 108-94-1
cyclohexanone

: 75-03-6
ethyl iodide

A: 2888-11-1
1,1'-bicyclohexane-1,1'-diol

B: 1940-18-7
1-ethylcyclohexanol

C: 108-93-0
cyclohexanol

Conditions

Conditions	Yield
With cerium; iodine 1) THF, -20 deg C, 2) THF, -20 deg C, 3 h; Yield given. Multistep reaction. Yields of byproduct given;

...Expand

: 25542-62-5
6-bromo-hexanoic acid ethyl ester

: 925-90-6
ethylmagnesium bromide

: 1940-18-7
1-ethylcyclohexanol

Conditions

Conditions	Yield
With N,N,N,N,N,N-hexamethylphosphoric triamide; samarium diiodide In tetrahydrofuran a) -78 deg C, 15 min, b) RT, 2 h;	7 % Chromat.

: 123-91-1
1,4-dioxane

: 78-27-3
1-Ethynyl-1-cyclohexanol

lithium alanate: lithium alanate

A: 1940-19-8
1-vinylcyclohexanol

B: 1940-18-7
1-ethylcyclohexanol

...Expand

: 108-94-1
cyclohexanone

ethyl Mg halide: ethyl Mg halide

: 1940-18-7
1-ethylcyclohexanol

Conditions

Conditions	Yield
Heating;

: 2386-64-3
ethylmagnesium chloride

: 108-94-1
cyclohexanone

: 1940-18-7
1-ethylcyclohexanol

Conditions

Conditions	Yield
In tetrahydrofuran

: 5445-24-9
1-n-propyl-1-cyclohexanol

: 1940-18-7
1-ethylcyclohexanol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: (diacetoxy)iodobenzene; iodine / CH2Cl2 / 0.17 h / 20 °C / UV-irradiation 2: tetrahydrofuran View Scheme

: 108-94-1
cyclohexanone

: 1940-18-7
1-ethylcyclohexanol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: KOH / 85 °C / 14710.2 Torr 2: Raney nickel / 20 °C / 36775.4 Torr / Hydrogenation.zuletzt bei 80grad/200 at View Scheme
Multi-step reaction with 2 steps 1: KOH / 85 °C / 14710.2 Torr 2: Raney nickel / 20 °C / 36775.4 Torr / Hydrogenation.zuletzt bei 80grad/200 at View Scheme
Multi-step reaction with 2 steps 1: sodium methylate / tetrahydrofuran / 21 h / 0 - 10 °C / 1500.15 - 15001.5 Torr / Autoclave; Inert atmosphere 2: hydrogen; 12 % Pd/C / 1,4-dioxane / 23 h / 20 °C / 3750.38 - 15001.5 Torr / Autoclave; Cooling with ice View Scheme

: 934-30-5, 1195-12-6, 20507-53-3, 58001-99-3, 67999-50-2, 67999-53-5, 74645-32-2, 108266-75-7, 120-74-1
5-norbornene-endo-2-carboxylic acid

: 1940-18-7
1-ethylcyclohexanol

: 823-76-7
Cyclohexyl methyl ketone

: 1940-18-7
1-ethylcyclohexanol

Conditions

Conditions	Yield
With hydrogen; nickel; platinum In 4-nitro-aniline

: 1678-91-7
ethyl-cyclohexane

A: 4423-94-3
2-ethylcyclohexanone

B: 5441-51-0
4-ethylcyclohexanone

C: 64847-85-4, 74006-73-8, 74006-74-9, 22461-89-8
3-ethyl cyclohexanone

D: 1940-18-7
1-ethylcyclohexanol

E: 823-76-7
Cyclohexyl methyl ketone

Conditions

Conditions	Yield
With bis(1-methyl-1-phenylethyl)peroxide; oxygen In acetonitrile at 25℃; for 9h; Kinetics; Reagent/catalyst; Solvent; UV-irradiation;

...Expand

: 1940-18-7
1-ethylcyclohexanol

: 1445-98-3
1-ethyl-1-chloro-cyclohexane

Conditions

Conditions	Yield
With 1,3,5-trichloro-2,4,6-triazine; N,N-dimethyl-formamide In dichloromethane at 25℃; for 4h;	98%
With pyridine; thionyl chloride
With hydrogenchloride

: 1940-18-7
1-ethylcyclohexanol

: 1-azido-1-ethylcyclohexane

Conditions

Conditions	Yield
With trimethylsilylazide; boron trifluoride diethyl etherate In dichloromethane at 0 - 20℃; for 18h;	97%
With sodium azide; trifluoroacetic acid In chloroform at -5 - 0℃; Inert atmosphere;	74%

: 1940-18-7
1-ethylcyclohexanol

: 2146-62-5
8-bromo-octan-3-one

Conditions

Conditions	Yield
With bromine; potassium carbonate In acetonitrile at 0℃;	93%
With bromine; potassium carbonate In chloroform at 0℃; for 10h; retro-Barbier fragmentation;	80%
With bromine; potassium carbonate In chloroform at 0℃; for 5h; Bromination; retro-Barbier fragmentation;	80%
With sodium hydroxide; bromine

: 1940-18-7
1-ethylcyclohexanol

: 151-50-8
potassium cyanide

: 99064-87-6
N-(1-ethyl-cyclohexyl)-formamide

Conditions

Conditions	Yield
Stage #1: 1-ethylcyclohexanol; potassium cyanide With sulfuric acid; acetic acid at 20℃; for 22.5h; Ritter Reaction; Stage #2: With sodium hydroxide; water at 0℃; pH=9;	90%
With sulfuric acid

: 5781-53-3
monomethyl oxalyl chloride

: 1940-18-7
1-ethylcyclohexanol

: 1-ethylcyclohexyl methyl oxalate

Conditions

Conditions	Yield
With dmap; triethylamine In tetrahydrofuran at 0 - 25℃; for 5h; Inert atmosphere;	82%

: 10026-04-7, 53609-55-5
tetrachlorosilane

: 1940-18-7
1-ethylcyclohexanol

: 858235-07-1
(Och-1-et)2SiCl2

Conditions

Conditions	Yield
With pyridine In benzene	80%
With pyridine In benzene	80%
With pyridine In benzene	80%

: 2465-65-8
Thiophosphorsaeure-O,O-diethylester

: 1940-18-7
1-ethylcyclohexanol

: 1258430-49-7
C12H25O3PS

Conditions

Conditions	Yield
With gallium(III) triflate In 1,2-dichloro-ethane at 75℃; Inert atmosphere;	79%

: 1940-18-7
1-ethylcyclohexanol

: 71-43-2
benzene

: 32658-82-5
1-(1-ethylcyclohexyl)benzene

Conditions

Conditions	Yield
With sulfuric acid for 3h; Ambient temperature;	58%
With sulfuric acid at 20℃; for 3h; Friedel-Crafts alkylation;	41%

: 377-38-8
tetrafluorosuccinic acid

: 1940-18-7
1-ethylcyclohexanol

: 530-62-1
1,1'-carbonyldiimidazole

: 1214274-91-5
C20H30F4O4

Conditions

Conditions	Yield
Stage #1: tetrafluorosuccinic acid; 1,1'-carbonyldiimidazole In tetrahydrofuran at 23 - 30℃; for 3h; Stage #2: 1-ethylcyclohexanol With dmap In tetrahydrofuran for 23h; Reflux;	56.6%

...Expand

: 1940-18-7
1-ethylcyclohexanol

: 108-24-7
acetic anhydride

A: 3742-81-2
1-ethylcyclohexyl acetate

B: 108-94-1
cyclohexanone

C: 431-03-8
dimethylglyoxal

Conditions

Conditions	Yield
With cobalt(II) chloride In acetonitrile at 70℃; for 8h;	A 33% B 19% C n/a

...Expand

: 699-30-9
perfluorosuccinic anhydride

: 1940-18-7
1-ethylcyclohexanol

: 1214274-91-5
C20H30F4O4

Conditions

Conditions	Yield
With dmap; triethylamine In tetrahydrofuran at 10 - 27℃; Cooling with ice;	12.6%

: 366-18-7
[2,2]bipyridinyl

: tetraaqua palladium(II) perchlorate

: 1940-18-7
1-ethylcyclohexanol

: (C5H4N)2PdC6H9CHCH3(1+)

Conditions

Conditions	Yield
In perchloric acid byproducts: ethylbenzene, 1-ethyl-1-cyclohexene; Pd(II) teraaqua complex reacted with alcohol at 35 °C for 80 min,bipyridine added;	1%
With iron(III) sulfate In perchloric acid byproducts: ethylbenzene, 1-ethyl-1-cyclohexene, 2-ethyl-1-cyclohehanone; Pd(II) teraaqua complex reacted with alcohol in presense of Fe(III) ion at 35 °C for 220 min, bipyridine added; further by-products: 3-ethyl-1-cyclohexanone, 4-ethyl-1-cyclohexanone; repeated repptn. from CH2Cl2 with diethyl ether; elem. anal.;

...Expand

: 1940-18-7
1-ethylcyclohexanol

: 151-50-8
potassium cyanide

: 2626-60-0
1-ethylcyclohexan-1-amine

Conditions

Conditions	Yield
With dibutyl ether; sulfuric acid Erhitzen des Reaktionsprodukts mit wss.HCl;

: 1940-18-7
1-ethylcyclohexanol

: 3338-04-3
2-ethyl-4,5,6,7-tetrahydro-3H-azepine

Conditions

Conditions	Yield
With sodium azide; ethanol; chloroform; sulfuric acid

: 1940-18-7
1-ethylcyclohexanol

: 1124-98-7
1-ethylcyclohexane-1-carboxylic acid

Conditions

Conditions	Yield
With formic acid; sulfuric acid

: 1940-18-7
1-ethylcyclohexanol

: 1453-24-3
1-ethylcyclohexene

Conditions

Conditions	Yield
With potassium hydrogensulfate
With aluminum oxide at 200 - 220℃;
With aluminum(III) sulfate

: 1940-18-7
1-ethylcyclohexanol

: 108249-59-8
1-((Z)-1,2-dibromo-vinyl)-cyclohexanol

Conditions

Conditions	Yield
With bromine; Petroleum ether; dibenzoyl peroxide Irradiation.UV-Licht;
With chloroform; bromine Irradiation.UV-Licht;

: 1940-18-7
1-ethylcyclohexanol

: 101105-87-7
4-nitro-benzoic acid-(1-ethyl-cyclohexyl ester)

: 1940-18-7
1-ethylcyclohexanol

: 18428-15-4
1-ethyl-cyclohexyl hydroperoxide

Conditions

Conditions	Yield
With sulfuric acid; dihydrogen peroxide at 0℃;

1-Ethylcyclohexanol Chemical Properties

IUPAC Name: 1-Ethylcyclohexan-1-ol
The MF of 1-Ethylcyclohexanol (CAS NO.1940-18-7) is C₈H₁₆O.

The MW of 1-Ethylcyclohexanol (CAS NO.1940-18-7) is 128.21.
Synonyms of 1-Ethylcyclohexanol (CAS NO.1940-18-7): 1-Aethyl-cyclohexanol-(1) ; 1-Ethylcyclohexanol ; Cyclohexanol, 1-ethyl-
Index of Refraction: 1.464
Density: 0.919 g/ml
Flash Point: 68.2 °C
Boiling Point: 166 °C
Melting Point: 34.5 °C

1-Ethylcyclohexanol Uses

1-Ethylcyclohexanol (CAS NO.1940-18-7) is used as chemical reagents, organic intermediates, fine chemicals, pharmaceutical research and development.

1-Ethylcyclohexanol Toxicity Data With Reference

1.		orl-mus LD50:1300 mg/kg		ARZNAD Arzneimittel-Forschung. Drug Research. 4 (1954),477.
2.		scu-mus LD50:840 mg/kg		ARZNAD Arzneimittel-Forschung. Drug Research. 5 (1955),161.

1-Ethylcyclohexanol Safety Profile

Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits acrid smoke and irritating fumes.Safety information of 1-Ethylcyclohexanol (CAS NO.1940-18-7):
Risk Statements
36/37/38 Irritating to eyes, respiratory system and skin
Safety Statements
26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36/37/39 Wear suitable protective clothing, gloves and eye/face protection

Product Name

1-Ethylcyclohexanol

Synthetic route

1-Ethylcyclohexanol Chemical Properties

1-Ethylcyclohexanol Uses

1-Ethylcyclohexanol Toxicity Data With Reference

1-Ethylcyclohexanol Safety Profile

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