1-Octacosanol supplier | CasNO.557-61-9

Name
1-Octacosanol
EINECS 209-181-2
CAS No. 557-61-9
Article Data21
CAS DataBase
Density 0.841 g/cm³
Solubility <0.1 g/100 mL at 21.5 °C in water
Melting Point 81-83 °C
Formula C₂₈H₅₈O
Boiling Point 428.1 °C at 760 mmHg
Molecular Weight 410.768
Flash Point 135.3 °C
Transport Information
Appearance white crystals or powder
Safety 22-24/25-37/39-26
Risk Codes 20/21/22-36/37/38
Molecular Structure
Hazard Symbols Xn
Synonyms montanyl alcohol;octacosyl alcohol;octacosan-1-ol;Cluytyl alcohol;Octacosanol;n-octacosanol;Octacosanol (Policosanol);Policosanol (Octacosanol);
PSA 20.23000
LogP 10.14120

Synthetic route

: 636583-59-0
(E,Z)-octacos-10-en-1-ol

: 557-61-9
octacosyl alcohol

Conditions

Conditions	Yield
With hydrogen; palladium on activated charcoal In methanol under 19001.3 Torr; for 6h;	97%
With palladium 10% on activated carbon; hydrogen In tetrahydrofuran at 80℃; under 26252.6 Torr; for 4h;	89%

: benzyl 1-octacosanol

: 557-61-9
octacosyl alcohol

Conditions

Conditions	Yield
With hydrogen; 5%-palladium/activated carbon In propan-1-ol at 90℃; under 3750.38 Torr; for 18h;	81%

: benzyl octacos-10-enol

: 557-61-9
octacosyl alcohol

Conditions

Conditions	Yield
With hydrogen; 5%-palladium/activated carbon In propan-1-ol at 90℃; under 3750.38 Torr; for 18h;	80%

: 2-octacosyloxy-tetrahydro-pyran

: 557-61-9
octacosyl alcohol

Conditions

Conditions	Yield
With hydrogenchloride; acetic acid In tetrahydrofuran; ethanol; water at 20℃; for 16h;	80%

: t-butyl-dimethyl-octacosyloxy-silane

: 557-61-9
octacosyl alcohol

Conditions

Conditions	Yield
With hydrogenchloride In ethanol at 72℃; for 5h;	77%

: 112-95-8
icosane

: 629-97-0
n-docosane

: 630-01-3
n-hexacosane

: 629-50-5
Tridecane

: 593-45-3
octadecane

: 646-31-1
tetracosane

: 630-02-4
octacosane

: 638-68-6
n-triacontane

A: 112-92-5
1-octadecanol

B: 629-96-9
n-eicosanol

C: 593-50-0
melissyl alcohol

D: 661-19-8
1-docosanol

E: 506-51-4
tetracosyl alcohol

F: 506-52-5
hexacosyl alcohol

G: 557-61-9
octacosyl alcohol

Conditions

Conditions	Yield
Stage #1: icosane; n-docosane; n-hexacosane; octadecane; tetracosane; octacosane; n-triacontane With oxygen at 30 - 50℃; under 1575.16 Torr; for 0.5h; Stage #2: Tridecane With titanium(IV) isopropylate at 30 - 50℃; under 1575.16 - 3750.38 Torr; for 6.86667h; Stage #3: With sulfuric acid; water at 80℃; Product distribution / selectivity;	A 17.66% B 19.46% C 0.1% D 13.62% E 6.93% F 2.04% G 0.48%

...Expand

: 112-95-8
icosane

: 629-97-0
n-docosane

: 630-01-3
n-hexacosane

: 593-45-3
octadecane

: 646-31-1
tetracosane

: 630-02-4
octacosane

: 638-68-6
n-triacontane

A: 112-92-5
1-octadecanol

B: 629-96-9
n-eicosanol

C: 593-50-0
melissyl alcohol

D: 661-19-8
1-docosanol

E: 506-51-4
tetracosyl alcohol

F: 506-52-5
hexacosyl alcohol

G: 557-61-9
octacosyl alcohol

Conditions

Conditions	Yield
Stage #1: icosane; n-docosane; n-hexacosane; octadecane; tetracosane; octacosane; n-triacontane With oxygen at 30 - 50℃; under 1575.16 - 3675.37 Torr; for 3h; Stage #2: With sulfuric acid; water Product distribution / selectivity;	A 12.4% B 13.4% C 0.05% D 7.8% E 3.2% F 1% G 0.2%

...Expand

: 6624-78-8
ethyl octacosanoate

: 557-61-9
octacosyl alcohol

Conditions

Conditions	Yield
With sodium; Petroleum ether; butan-1-ol
With lithium aluminium tetrahydride

: 55682-92-3
methyl octacosanoate

: 557-61-9
octacosyl alcohol

Conditions

Conditions	Yield
With lithium aluminium tetrahydride In tetrahydrofuran for 1h; Heating;

: 25728-82-9
sodium octacosanoate

: 557-61-9
octacosyl alcohol

Conditions

Conditions	Yield
With lithium aluminium tetrahydride In tetrahydrofuran Heating; Yield given;

: 148172-69-4
Octacos-9-yn-1-ol

: 557-61-9
octacosyl alcohol

Conditions

Conditions	Yield
With hydrogen; palladium on activated charcoal In ethanol

: Erythrinasinate

A: 557-61-9
octacosyl alcohol

B: 537-73-5
trans-3-hydroxy-4-methoxycinnamic acid

Conditions

Conditions	Yield
With potassium hydroxide In chloroform for 1h; Heating;	A 50 mg B 8 mg

: octacosanyl triacontanoate

A: 557-61-9
octacosyl alcohol

B: 506-50-3
melissic acid

Conditions

Conditions	Yield
With potassium hydroxide In ethanol for 5h; Heating;

: (2R,3S,4S,5R,6R)-2-Hydroxymethyl-6-octacosyloxy-tetrahydro-pyran-3,4,5-triol

: 557-61-9
octacosyl alcohol

Conditions

Conditions	Yield
With hydrogenchloride In methanol for 5h; Heating;

: Benzoic acid (2R,3R,4S,5R,6R)-3,5-dihydroxy-2-hydroxymethyl-6-octacosyloxy-tetrahydro-pyran-4-yl ester

: 557-61-9
octacosyl alcohol

Conditions

Conditions	Yield
With hydrogenchloride In methanol for 5h; Heating;
Multi-step reaction with 2 steps 1: KOH / methanol / 5 h / Heating 2: HCl / methanol / 5 h / Heating View Scheme

: 505-95-3
12-hydroxydodecanoic acid

: 557-61-9
octacosyl alcohol

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: 90 percent / 50percent HBr / acetic acid / 5 h / Heating 2: EtONa / ethanol / 0.5 h / Heating 3: Li2CuCl4 / tetrahydrofuran / 4 h / -10 - -5 °C 4: LiAlH4 / tetrahydrofuran / Heating View Scheme

: 73367-80-3
12-bromododecanoic acid

: 557-61-9
octacosyl alcohol

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: EtONa / ethanol / 0.5 h / Heating 2: Li2CuCl4 / tetrahydrofuran / 4 h / -10 - -5 °C 3: LiAlH4 / tetrahydrofuran / Heating View Scheme

octacosyl alcohol: octacosyl alcohol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: Li2CuCl4 / tetrahydrofuran / 4 h / -10 - -5 °C 2: LiAlH4 / tetrahydrofuran / Heating View Scheme

: 17643-36-6
9-decyn-1-ol

: 557-61-9
octacosyl alcohol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 1.) n-BuLi / 1.) HMPA. 2.) HMPA 2: H2 / Pd/C / ethanol View Scheme

: 112-89-0
1-Bromooctadecane

: 557-61-9
octacosyl alcohol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 1.) n-BuLi / 1.) HMPA. 2.) HMPA 2: H2 / Pd/C / ethanol View Scheme

: 35444-44-1
methyl adipoyl chloride

: 557-61-9
octacosyl alcohol

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: 65 percent / stannic chloride / benzene / 2 h / Ambient temperature 2: BF3(OC2H5)3 / CHCl3 / Ambient temperature 3: W6 Raney nickel / ethanol / Heating 4: LAH / tetrahydrofuran / 1 h / Heating View Scheme

: 102945-07-3
2-octadecylthiophene

: 557-61-9
octacosyl alcohol

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: 65 percent / stannic chloride / benzene / 2 h / Ambient temperature 2: BF3(OC2H5)3 / CHCl3 / Ambient temperature 3: W6 Raney nickel / ethanol / Heating 4: LAH / tetrahydrofuran / 1 h / Heating View Scheme

: 111514-85-3
6-(5-Octadecyl-thiophen-2-yl)-6-oxo-hexanoic acid methyl ester

: 557-61-9
octacosyl alcohol

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: BF3(OC2H5)3 / CHCl3 / Ambient temperature 2: W6 Raney nickel / ethanol / Heating 3: LAH / tetrahydrofuran / 1 h / Heating View Scheme

: 111514-96-6
5-[2-(5-Octadecyl-thiophen-2-yl)-[1,3]dithiolan-2-yl]-pentanoic acid methyl ester

: 557-61-9
octacosyl alcohol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: W6 Raney nickel / ethanol / Heating 2: LAH / tetrahydrofuran / 1 h / Heating View Scheme

: C30H62O2

: 557-61-9
octacosyl alcohol

Conditions

Conditions	Yield
With methanol; hydrogenchloride Heating / reflux;
With methanol; hydrogenchloride Heating / reflux;

: BrMg(1+)*C10H20BrO(1-)

: n-octadecylmagnesium chloride

: 557-61-9
octacosyl alcohol

Conditions

Conditions	Yield
Stage #1: BrMg(1+)*C10H20BrO(1-); dilithium tetrachlorocuprate In tetrahydrofuran at -20℃; for 0.333333h; Stage #2: n-octadecylmagnesium chloride In tetrahydrofuran at -20 - 20℃; Stage #3: With ammonium chloride In tetrahydrofuran; water

: 1611-56-9
1-Bromo-11-hydroxyundecane

: 557-61-9
octacosyl alcohol

Conditions

Conditions	Yield
Multi-step reaction with 7 steps 1: triethylamine / dichloromethane 2: n-butyllithium; N,N,N,N,N,N-hexamethylphosphoric triamide / tetrahydrofuran 3: hydrogen; palladium 10% on activated carbon / ethyl acetate 4: pyridinium chlorochromate / dichloromethane 5: sodium hexamethyldisilazane / tetrahydrofuran 6: tetrabutyl ammonium fluoride / tetrahydrofuran 7: hydrogen; palladium 10% on activated carbon / ethyl acetate View Scheme

Yield

Multi-step reaction with 7 steps
1: triethylamine / dichloromethane
2: n-butyllithium; N,N,N,N,N,N-hexamethylphosphoric triamide / tetrahydrofuran
3: hydrogen; palladium 10% on activated carbon / ethyl acetate
4: pyridinium chlorochromate / dichloromethane
5: sodium hexamethyldisilazane / tetrahydrofuran
6: tetrabutyl ammonium fluoride / tetrahydrofuran
7: hydrogen; palladium 10% on activated carbon / ethyl acetate
View Scheme

: 172995-51-6
(11-bromoundecyloxy)(tert-butyl)diphenylsilane

: 557-61-9
octacosyl alcohol

Conditions

Conditions	Yield
Multi-step reaction with 6 steps 1: n-butyllithium; N,N,N,N,N,N-hexamethylphosphoric triamide / tetrahydrofuran 2: hydrogen; palladium 10% on activated carbon / ethyl acetate 3: pyridinium chlorochromate / dichloromethane 4: sodium hexamethyldisilazane / tetrahydrofuran 5: tetrabutyl ammonium fluoride / tetrahydrofuran 6: hydrogen; palladium 10% on activated carbon / ethyl acetate View Scheme

: 1538660-98-8
C30H44O2Si

: 557-61-9
octacosyl alcohol

Conditions

Conditions	Yield
Multi-step reaction with 5 steps 1: hydrogen; palladium 10% on activated carbon / ethyl acetate 2: pyridinium chlorochromate / dichloromethane 3: sodium hexamethyldisilazane / tetrahydrofuran 4: tetrabutyl ammonium fluoride / tetrahydrofuran 5: hydrogen; palladium 10% on activated carbon / ethyl acetate View Scheme

: 557-61-9
octacosyl alcohol

: 124-63-0
methanesulfonyl chloride

: C29H60O3S

Conditions

Conditions	Yield
With triethylamine In tetrahydrofuran at 80℃;	70%

: 557-61-9
octacosyl alcohol

: 22725-64-0
octacosanal aldehyde

Conditions

Conditions	Yield
Stage #1: octacosyl alcohol With calcium carbonate In dichloromethane at 20℃; for 0.5h; Molecular sieves (MS4A); Stage #2: With pyridinium chlorochromate In dichloromethane at 20℃; for 2h; Stage #3: In hexane; dichloromethane for 0.25h;	45.9%
With pyridinium chlorochromate Oxidation;

: 557-61-9
octacosyl alcohol

: 62154-80-7
octacosanol iodide

Conditions

Conditions	Yield
With phosphorus; iodine

: 557-61-9
octacosyl alcohol

: 506-48-9
octacosanoic acid

Conditions

Conditions	Yield
With chromium; acetic acid
Jones Oxidation;

: 557-61-9
octacosyl alcohol

: 108-24-7
acetic anhydride

: 18206-97-8
octacosanol acetate

Conditions

Conditions	Yield
With sodium acetate
With pyridine
In pyridine

: 557-61-9
octacosyl alcohol

: 1476-23-9
allylisocyanate

: 121706-85-2
allyl-carbamic acid octacosyl ester

Conditions

Conditions	Yield
With benzene

: 557-61-9
octacosyl alcohol

: 145205-03-4
(E)-3-<3-Methoxy-4-(tetrahydropyran-2-yloxy)phenyl>prop-2-enoic acid

: (E)-3-[3-Methoxy-4-(tetrahydro-pyran-2-yloxy)-phenyl]-acrylic acid octacosyl ester

Conditions

Conditions	Yield
With dicyclohexyl-carbodiimide In pyridine at 50 - 55℃;

: 557-61-9
octacosyl alcohol

: 16331-21-8
1-bromo-octacosane

Conditions

Conditions	Yield
With sulfuric acid; hydrogen bromide at 90 - 110℃;

: 557-61-9
octacosyl alcohol

: oleoyl chloride

: octacosyl oleate

Conditions

Conditions	Yield
With pyridine In tetrachloromethane Ambient temperature;

: 557-61-9
octacosyl alcohol

: 112-67-4
n-hexadecanoyl chloride

: octacosanyl hexadecanoate

Conditions

Conditions	Yield
With pyridine In tetrachloromethane Ambient temperature;

1-Octacosanol Chemical Properties

IUPAC Name: Octacosan-1-ol
Molecular Formula: C₂₈H₅₈O
Molecular Weight: 410.76g'/mol
EINECS: 209-181-2
Melting Point: 81-83 ºC
Freely Rotating Bonds: 27
Polar Surface Area: 9.23 Å²
Index of Refraction: 1.458
Molar Refractivity: 133.3 cm³
Molar Volume: 488.2 cm³
Polarizability: 52.84 ×10^-24cm³
Surface Tension: 32.1 dyne/cm
Density: 0.841 g/cm³
Flash Point: 135.3 °C
Enthalpy of Vaporization: 78.89 kJ/mol
Boiling Point: 428.1 °C at 760 mmHg
Vapour Pressure: 3.99E-09 mmHg at 25°C
The Cas Register Number of 1-Octacosanol is 557-61-9 .The chemical synonyms of 1-Octacosanol (CAS No. 557-61-9) are 1-Octacosanol ; Octacosyl alcohol ; Octacosanol ; Octacosanol, 1- ; N-Octacosanol ; Montanyl alcohol ; Octacosanol,95% ; Octacosan-1-ol .Product categories of 1-Octacosanol (CAS No. 557-61-9) are Miscellaneous ; 1-Alkanols ; Biochemistry ; Higher fatty acids & Higher alcohols ; Monofunctional & Alpha,omega-Bifunctional alkanes ; Monofunctional alkanes ; Saturated higher alcohols ; Nutritional fortification substances ; Reduce hypertension ; Fatty alcoholsnutrition research ; Biochemicals found in plants ; Fatty acids ; Other biochemical ; Saturated fatty acids and derivatives .The molecular structure of 1-Octacosanol (CAS No. 557-61-9) is.

1-Octacosanol Uses

1-Octacosanol (CAS NO.557-61-9) can be used as significantly reduce total cholesterol, and helps patients with Parkinson's Disease. Sometimes it can used as the major wax constituent.

1-Octacosanol Safety Profile

Hazard Codes: Harmful Xn
Risk Statements: 20/21/22-36/37/38
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 22-24/25-37/39-26
S22: Do not breathe dust.
S24/25: Avoid contact with skin and eyes.
S37/39: Wear suitable gloves and eye/face protection.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany: -

1-Octacosanol Specification

1-Octacosanol , its cas register number is 557-61-9. It also can be called Cluytyl alcohol ; Octacosyl alcohol ; Policosanol ; and Montanyl alcohol . The extinguishing agent of 1-Octacosanol (CAS No. 557-61-9) are dry powder, foam, sand, carbon dioxide, water mist.

Product Name

1-Octacosanol

Synthetic route

1-Octacosanol Chemical Properties

1-Octacosanol Uses

1-Octacosanol Safety Profile

1-Octacosanol Specification

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