Product Name

  • Name

    1-Hydroxyoctadecane

  • EINECS 204-017-6
  • CAS No. 112-92-5
  • Article Data236
  • CAS DataBase
  • Density 0.837 g/cm3
  • Solubility insoluble in water
  • Melting Point 55-58 °C
  • Formula C18H38O
  • Boiling Point 334.3 °C at 760 mmHg
  • Molecular Weight 270.499
  • Flash Point 138.7 °C
  • Transport Information UN 1986
  • Appearance White flakes
  • Safety 24/25
  • Risk Codes
  • Molecular Structure Molecular Structure of 112-92-5 (1-Hydroxyoctadecane)
  • Hazard Symbols
  • Synonyms 1-Hydroxyoctadecane;1-Stearyl alcohol;Adol 62;Adol 64;Adol 68;Alfol 18;Alfol 18NF;Atalco S;CO 1895;CO 1895F;CO 1897;Cachalot S 43;Conol 1675;Conol 30F;Conol 30S;Conol 30SS;Crodacol S;Crodacol S 70;Crodacol S 95;Crodacol S 95 NF;Hainol18SS;Hyfatol 18-95;Hyfatol 18-98;Kalchol 8098;Kalcohl 80;Kalcohl 8098;Kalcohl 8099;Kalcol 8098;Lanette 18;Lanette 18DEO;Lanol S;Laurex 18;Lorol28;Lorol C 18;NSC 5379;Octadecanol;Octadecyl alcohol;Rofamol;Sipol S;Siponol S;Siponol SC;Stearic alcohol;Stearol;Stearyl alcohol;Steraffine;Tego alkanol 18;VLTN 6;n-Octadecanol;n-Octadecyl alcohol;
  • PSA 20.23000
  • LogP 6.24020

Synthetic route

1-octadecanol
112-92-5

1-octadecanol

(2,6-dichloro-5-methoxyphenyl)-(2,4-dichlorophenyl)methyl octadecyl ether
1205121-90-9

(2,6-dichloro-5-methoxyphenyl)-(2,4-dichlorophenyl)methyl octadecyl ether

1-octadecanol
112-92-5

1-octadecanol

Conditions
ConditionsYield
With trifluoroacetic acid In dichloromethane for 4h;100%
stearic acid ethyl ester
111-61-5

stearic acid ethyl ester

1-octadecanol
112-92-5

1-octadecanol

Conditions
ConditionsYield
With hydrogen In dodecane at 200℃; under 37503.8 Torr; for 8h; Temperature; Pressure;99.8%
With C30H34Cl2N2P2Ru; potassium methanolate; hydrogen In tetrahydrofuran at 100℃; under 38002.6 - 76005.1 Torr; for 15h; Glovebox; Autoclave;98%
With methanol; sodium tetrahydroborate; sodium ethanolate at 40℃; Reagent/catalyst;72%
Methyl stearate
112-61-8

Methyl stearate

1-octadecanol
112-92-5

1-octadecanol

Conditions
ConditionsYield
With sodium tetrahydroborate; N,N-dimethyl-aniline; zinc(II) chloride In tetrahydrofuran for 2h; Heating;99%
With lithium aluminium tetrahydride In toluene at 90℃;98%
With lithium borohydride; 9-methoxy-9-BBN In diethyl ether for 0.5h; Heating;97%
2-(octadecyloxy)tetrahydro-2H-pyran
66938-10-1

2-(octadecyloxy)tetrahydro-2H-pyran

1-octadecanol
112-92-5

1-octadecanol

Conditions
ConditionsYield
poly(4-vinylpyridinium) p-toluenesulfonate In tetrahydrofuran; ethanol at 75℃; for 60h; Hydrolysis;99%
With trichloroisocyanuric acid In methanol at 20℃; for 6h;94%
With iodine In methanol for 0.2h; microwave irradiation;80%
glycerol tristearate
555-43-1

glycerol tristearate

1-octadecanol
112-92-5

1-octadecanol

Conditions
ConditionsYield
With C24H38Cl2N3PRu; hydrogen; sodium methylate In isopropyl alcohol at 100℃; under 38002.6 Torr; for 2h; Autoclave;98%
Stage #1: glycerol tristearate With diethylzinc; lithium chloride In tetrahydrofuran; hexane at 20℃; for 6h; Inert atmosphere;
Stage #2: With sodium hydroxide In tetrahydrofuran; hexane; water at 20℃; for 8h; Inert atmosphere; chemoselective reaction;
98%
With 5 wt% Re/TiO2; hydrogen In neat (no solvent) at 230℃; under 37503.8 Torr; for 30h; Autoclave;82%
1-(tert-butyldimethylsilyloxy)octadecan
65598-00-7

1-(tert-butyldimethylsilyloxy)octadecan

1-octadecanol
112-92-5

1-octadecanol

Conditions
ConditionsYield
With sodium hydride In N,N,N,N,N,N-hexamethylphosphoric triamide at 25℃; for 10h;97%
With sodium hydrogen sulfate; silica gel In dichloromethane at 20℃; for 0.5h;92%
With ethane-1,2-dithiol; nickel dichloride In methanol; dichloromethane at 20℃; for 0.166667h;90%
trifluoroacetate 1-octadecanol
79392-43-1

trifluoroacetate 1-octadecanol

1-octadecanol
112-92-5

1-octadecanol

Conditions
ConditionsYield
With silica gel; triethylamine In diethyl ether; Petroleum ether Substitution; Detrifluoroacetylation;97%
stearic acid
57-11-4

stearic acid

1-octadecanol
112-92-5

1-octadecanol

Conditions
ConditionsYield
With 1,1,3,3-Tetramethyldisiloxane; copper(II) bis(trifluoromethanesulfonate) In toluene at 80℃; for 16h; sealed tube;96%
With sodium aluminum tetrahydride In tetrahydrofuran; toluene at 110℃;94%
With sodium tetrahydroborate; benzene-1,2-diol; trifluoroacetic acid In tetrahydrofuran at 25℃; for 4h;94%
stearyl acetate
822-23-1

stearyl acetate

1-octadecanol
112-92-5

1-octadecanol

Conditions
ConditionsYield
With methanol; oxo[hexa(trifluoroacetato)]tetrazinc for 12h; Reflux; Inert atmosphere;96%
With 18-crown-6 ether; tert-butylamine In diethyl ether firther solvent;78%
n-Octadecanal
638-66-4

n-Octadecanal

1-octadecanol
112-92-5

1-octadecanol

Conditions
ConditionsYield
With water; magnesium; cadmium(II) chloride In tetrahydrofuran for 0.25h;95%
With tri-n-butyl-tin hydride; silica gel In dichloromethane for 24h; Ambient temperature;82%
With acetic acid; zinc und nachfolgende Verseifung des erhaltenen Octadecylacetats mittels alkoholischer Kalilauge;
stearyl trityl ether

stearyl trityl ether

1-octadecanol
112-92-5

1-octadecanol

Conditions
ConditionsYield
With sodium hydrogen sulfate; silica gel In methanol; dichloromethane at 20℃; for 3.5h;94%
With lithium chloride In methanol for 12h; Reflux;88%
(1-Methyl-1-octadecyloxy-ethoxymethyl)-benzene
89538-90-9

(1-Methyl-1-octadecyloxy-ethoxymethyl)-benzene

1-octadecanol
112-92-5

1-octadecanol

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In ethanol under 760 Torr; Ambient temperature;92%
cis-Octadecenoic acid
112-80-1

cis-Octadecenoic acid

1-octadecanol
112-92-5

1-octadecanol

Conditions
ConditionsYield
With isopropyl alcohol at 200℃; for 4h; Temperature;91.9%
With cobalt at 135℃; under 147102 Torr; Hydrogenation;
With hydrogen In dodecane at 290℃; under 38002.6 Torr; Activation energy; Autoclave;
oleoyl alcohol
143-28-2

oleoyl alcohol

1-octadecanol
112-92-5

1-octadecanol

Conditions
ConditionsYield
With hydrogen; TMSB; palladium In ethanol at 20℃; under 760 Torr; for 42h;91%
With nickel Hydrogenation;
With diethyl ether; hydrogen; platinum
With nickel Hydrogenation;
O-Octadecyl thiobenzoate
57701-11-8

O-Octadecyl thiobenzoate

A

1-octadecanol
112-92-5

1-octadecanol

B

benzyl-octadecyl ether
120726-66-1

benzyl-octadecyl ether

Conditions
ConditionsYield
With 2,2'-azobis(isobutyronitrile); triphenylstannane In toluene at 110℃; for 0.333333h; Yields of byproduct given;A n/a
B 91%
diberomo methyl oleate

diberomo methyl oleate

1-octadecanol
112-92-5

1-octadecanol

Conditions
ConditionsYield
With sodium tetrahydroborate In tetrahydrofuran for 2h; Heating;91%
octadecyl adamantane-1-carboxylate

octadecyl adamantane-1-carboxylate

A

1-octadecanol
112-92-5

1-octadecanol

B

octadecane
593-45-3

octadecane

C

1-Adamantanecarboxylic acid
828-51-3

1-Adamantanecarboxylic acid

Conditions
ConditionsYield
With 18-crown-6 ether; tert-butylamine In diethyl etherA 53%
B 40%
C 90%
Octadecanoic acid (1S,7R)-3,5-dioxo-4-aza-tricyclo[5.2.1.02,6]dec-8-en-4-yl ester
77290-17-6

Octadecanoic acid (1S,7R)-3,5-dioxo-4-aza-tricyclo[5.2.1.02,6]dec-8-en-4-yl ester

1-octadecanol
112-92-5

1-octadecanol

Conditions
ConditionsYield
With sodium tetrahydroborate In tetrahydrofuran; methanol for 1h; Ambient temperature;90%
4,4,5,5-tetramethyl-2-(octadecyloxy)-1,3,2-dioxaborolane

4,4,5,5-tetramethyl-2-(octadecyloxy)-1,3,2-dioxaborolane

1-octadecanol
112-92-5

1-octadecanol

Conditions
ConditionsYield
With water; silica gel In methanol at 60℃; Inert atmosphere;89%
1-(NN-diethylaminothiocarbonyloxy)octadecane
73532-45-3

1-(NN-diethylaminothiocarbonyloxy)octadecane

A

1-octadecanol
112-92-5

1-octadecanol

B

octadecane
593-45-3

octadecane

Conditions
ConditionsYield
With 18-crown-6 ether; tert-butylamine In tetrahydrofuranA 12%
B 87%
With 18-crown-6 ether; tert-butylamine In tetrahydrofuran Ambient temperature;A 12%
B 87%
Octadecanoic acid 2,3,4,5-tetrachloro-6-octadecanoyloxy-phenyl ester
142834-93-3

Octadecanoic acid 2,3,4,5-tetrachloro-6-octadecanoyloxy-phenyl ester

1-octadecanol
112-92-5

1-octadecanol

Conditions
ConditionsYield
With sodium tetrahydroborate In tetrahydrofuran 1) 0 deg C, 2 h, 2) rt, 2 h;85%
ethanol
64-17-5

ethanol

stearic acid
57-11-4

stearic acid

A

1-octadecanol
112-92-5

1-octadecanol

B

stearic acid ethyl ester
111-61-5

stearic acid ethyl ester

Conditions
ConditionsYield
With hydrogen at 320℃; under 37503.8 Torr; Pressure; Temperature; Flow reactor;A 83%
B 13%
stearyl trityl ether

stearyl trityl ether

A

1-octadecanol
112-92-5

1-octadecanol

B

trityl chloride
76-83-5

trityl chloride

Conditions
ConditionsYield
With indium; ammonium chloride In methanol for 35h; Reagent/catalyst; Solvent; Temperature; Reflux;A 80%
B 65%
O-Octadecyl thiobenzoate
57701-11-8

O-Octadecyl thiobenzoate

1-octadecanol
112-92-5

1-octadecanol

Conditions
ConditionsYield
With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride In toluene at 110℃; for 0.333333h;77%
2-hexadecyloxirane
7390-81-0

2-hexadecyloxirane

1-octadecanol
112-92-5

1-octadecanol

Conditions
ConditionsYield
With bis(cyclopentadienyl)titanium dichloride; manganese; water In tetrahydrofuran at 20℃; for 24h; Inert atmosphere;75%
octadecyl adamantane-1-carboxylate

octadecyl adamantane-1-carboxylate

A

1-octadecanol
112-92-5

1-octadecanol

B

octadecane
593-45-3

octadecane

Conditions
ConditionsYield
With sodium-potassium alloy; 18-crown-6 ether; tert-butylamine further reagent;A 24%
B 74%
stearic acid
57-11-4

stearic acid

A

1-octadecanol
112-92-5

1-octadecanol

B

hepatdecane
629-78-7

hepatdecane

C

octadecane
593-45-3

octadecane

Conditions
ConditionsYield
With hydrogen In decane at 160℃; under 30003 Torr; for 4h; Temperature; Autoclave;A n/a
B n/a
C 68.39%
With hydrogen In dodecane at 289.84℃; under 6000.6 Torr; for 4h; Autoclave;
With hydrogen In cyclohexane at 179.84℃; under 15001.5 Torr; for 1h; Reagent/catalyst; Pressure; Sealed tube;
n-octadodecyl N-methanesulfonyl thioxocarbamate
175725-46-9

n-octadodecyl N-methanesulfonyl thioxocarbamate

A

1-octadecanol
112-92-5

1-octadecanol

B

O-octadecanylthioxocarbamate

O-octadecanylthioxocarbamate

Conditions
ConditionsYield
With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride In benzene for 3h; Heating;A 67%
B 23%
1-octadecanol
112-92-5

1-octadecanol

3-tert-butoxycarbonyl-2-chloro-1,3,2-oxazaphospholidine
148160-26-3

3-tert-butoxycarbonyl-2-chloro-1,3,2-oxazaphospholidine

3-tert-butoxycarbonyl-2-octadecyloxy-1,3,2-oxazaphospholidine
148160-29-6

3-tert-butoxycarbonyl-2-octadecyloxy-1,3,2-oxazaphospholidine

Conditions
ConditionsYield
With triethylamine In dichloromethane -40 deg C to r.t., 1 h;100%
1-octadecanol
112-92-5

1-octadecanol

2-chloro-3-methyl-1,3,2-oxazaphospholidine
22082-71-9

2-chloro-3-methyl-1,3,2-oxazaphospholidine

3-Methyl-2-octadecyloxy-1,3,2-oxazaphosphacyclopentane
104702-25-2

3-Methyl-2-octadecyloxy-1,3,2-oxazaphosphacyclopentane

Conditions
ConditionsYield
With triethylamine In dichloromethane for 2h; -40 deg C to RT;100%
With triethylamine In dichloromethane at -60℃; Yield given;
1-octadecanol
112-92-5

1-octadecanol

epichlorohydrin
106-89-8

epichlorohydrin

octadecyl glycidyl ether
16245-97-9

octadecyl glycidyl ether

Conditions
ConditionsYield
With sodium hydroxide; Aliquat 336 In cyclohexane Heating;100%
With sodium hydroxide; Aliquat 336 In cyclohexane Heating;99%
With sodium hydroxide; Aliquat 336 In cyclohexane for 4h; Heating;99%
1-octadecanol
112-92-5

1-octadecanol

acetic anhydride
108-24-7

acetic anhydride

stearyl acetate
822-23-1

stearyl acetate

Conditions
ConditionsYield
With trimethylsilyl trifluoromethanesulfonate In dichloromethane at 0℃; for 0.00833333h;100%
With trimethylsilyl trifluoromethanesulfonate In dichloromethane at 0℃; for 0.00833333h;100%
With silica gel-supported phosphotungstic acid In chloroform at 20℃; for 0.0333333h;98%
1-octadecanol
112-92-5

1-octadecanol

[4-(7-Diethylamino-2-oxo-2H-chromen-3-yl)-phenyl]-oxo-acetonitrile
203256-20-6

[4-(7-Diethylamino-2-oxo-2H-chromen-3-yl)-phenyl]-oxo-acetonitrile

4-(7-Diethylamino-2-oxo-2H-chromen-3-yl)-benzoic acid octadecyl ester

4-(7-Diethylamino-2-oxo-2H-chromen-3-yl)-benzoic acid octadecyl ester

Conditions
ConditionsYield
With dmap In acetonitrile for 1.5h; Heating;100%
1,4-benzenedicarboxylic acid dimethyl ester
120-61-6

1,4-benzenedicarboxylic acid dimethyl ester

1-octadecanol
112-92-5

1-octadecanol

1-methyl-4-octadecyl terephthalate
43049-06-5

1-methyl-4-octadecyl terephthalate

Conditions
ConditionsYield
Stage #1: 1,4-benzenedicarboxylic acid dimethyl ester; 1-octadecanol In xylene for 0.5h; Heating;
Stage #2: With TiO(acac)2 In xylene for 15h; Heating;
100%
1-octadecanol
112-92-5

1-octadecanol

Methyl cinnamate
103-26-4

Methyl cinnamate

octadecyl (2E)-3-phenylprop-2-enoate
61415-12-1

octadecyl (2E)-3-phenylprop-2-enoate

Conditions
ConditionsYield
Stage #1: 1-octadecanol; Methyl cinnamate In xylene for 0.5h; Heating;
Stage #2: With TiO(acac)2 In xylene for 14h; Heating;
100%
1-octadecanol
112-92-5

1-octadecanol

methyl 3-(4-hydroxy-3,5-di-tert-butyl)phenylpropanoate
6386-38-5

methyl 3-(4-hydroxy-3,5-di-tert-butyl)phenylpropanoate

Octadecyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate
2082-79-3

Octadecyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate

Conditions
ConditionsYield
Stage #1: 1-octadecanol; methyl 3-(4-hydroxy-3,5-di-tert-butyl)phenylpropanoate In xylene for 0.5h; Heating;
Stage #2: With TiO(acac)2 In xylene for 11h; Heating;
100%
With sodium montmorillonite In methanol at 110 - 120℃; under 15001.5 - 22502.3 Torr; for 7h; Reagent/catalyst; Inert atmosphere;99.1%
Stage #1: methyl 3-(4-hydroxy-3,5-di-tert-butyl)phenylpropanoate With tetramethoxytitanium; tetrabutoxytitanium In ethylene glycol; toluene for 1.33333h; Inert atmosphere; Cooling with ice;
Stage #2: 1-octadecanol With zirconium (IV) butoxide at 80℃; for 3h; Reagent/catalyst; Temperature; Inert atmosphere; Cooling with ice;
99.6%
1-octadecanol
112-92-5

1-octadecanol

methyl salicylate
119-36-8

methyl salicylate

octadecyl 2-hydroxybenzoate
14971-14-3

octadecyl 2-hydroxybenzoate

Conditions
ConditionsYield
Stage #1: 1-octadecanol; methyl salicylate In xylene for 0.5h; Heating;
Stage #2: With TiO(acac)2 In xylene for 10h; Heating;
100%
1-octadecanol
112-92-5

1-octadecanol

[ethyl undecanoate]-isobutyl-POSS
1021693-09-3

[ethyl undecanoate]-isobutyl-POSS

C57H120O14Si8
1021693-10-6

C57H120O14Si8

Conditions
ConditionsYield
toluene-4-sulfonic acid In toluene for 5h; Heating / reflux;100%
1-octadecanol
112-92-5

1-octadecanol

1-chlorooctadecane
3386-33-2

1-chlorooctadecane

Conditions
ConditionsYield
With hydrogenchloride; N-n-octylalkylpyridinium chlorides; mixture of at 150℃; for 8h; Product distribution / selectivity;99.8%
With Amberlite IRA 93 (PCl5 form) In benzene for 5h; Heating;96%
With hydrogenchloride; trimethyloctadecylammonium chloride for 10h; Irradiation;77%
1-octadecanol
112-92-5

1-octadecanol

ethyl acetate
141-78-6

ethyl acetate

stearyl acetate
822-23-1

stearyl acetate

Conditions
ConditionsYield
With C12F18O13Zn4 for 38h; Reflux; Inert atmosphere;99%
With iodine for 2h; Reflux; chemoselective reaction;98%
With aluminum oxide at 25 - 30℃; for 1h;96%
With copper(II) nitrate for 30h; Heating;85%
With cerium(IV) trifluoromethanesulfonate at 20℃; for 1h; Acetylation;75%
1-octadecanol
112-92-5

1-octadecanol

2,4,4,6-Tetrabromo-2,5-cyclohexadien-1-one
20244-61-5

2,4,4,6-Tetrabromo-2,5-cyclohexadien-1-one

1-Bromooctadecane
112-89-0

1-Bromooctadecane

Conditions
ConditionsYield
With triphenylphosphine In dichloromethane for 4h; Ambient temperature;99%
1-octadecanol
112-92-5

1-octadecanol

acetic acid
64-19-7

acetic acid

stearyl acetate
822-23-1

stearyl acetate

Conditions
ConditionsYield
With sulfonic acid-functionalized periodic mesoporous organosilicas with ethyl bridging group at 60℃; for 24h;99%
With copper(II) nitrate for 3.5h; Heating;90%
With cerium(IV) trifluoromethanesulfonate at 20℃; for 2h; Acetylation;90%
With sulfonic acid immobilized on a periodic mesoporous organosilica with an imidazolium framework In neat (no solvent) at 60℃; for 19h; Green chemistry;90%
1-octadecanol
112-92-5

1-octadecanol

formic acid ethyl ester
109-94-4

formic acid ethyl ester

Octadecyl formate
5451-75-2

Octadecyl formate

Conditions
ConditionsYield
With copper(II) nitrate for 4h; Heating;99%
With cerium(IV) trifluoromethanesulfonate at 20℃; for 0.166667h; Formylation;65%
thiophene-2-carboxylic acid methyl ester
5380-42-7

thiophene-2-carboxylic acid methyl ester

1-octadecanol
112-92-5

1-octadecanol

octadecyl thiophene-2-carboxylate

octadecyl thiophene-2-carboxylate

Conditions
ConditionsYield
Stage #1: thiophene-2-carboxylic acid methyl ester; 1-octadecanol In xylene for 0.5h; Heating;
Stage #2: With TiO(acac)2 In xylene for 13h; Heating;
99%
With iron(III)-acetylacetonate; sodium carbonate In n-heptane at 105℃; for 5h; Inert atmosphere;96%
1-octadecanol
112-92-5

1-octadecanol

4-nitrobenzoic acid methyl ester
619-50-1

4-nitrobenzoic acid methyl ester

octadecyl 4-nitro-benzoate
56426-96-1

octadecyl 4-nitro-benzoate

Conditions
ConditionsYield
Stage #1: 1-octadecanol; 4-nitrobenzoic acid methyl ester In xylene for 0.5h; Heating;
Stage #2: With TiO(acac)2 In xylene for 4.5h; Heating;
99%
1-octadecanol
112-92-5

1-octadecanol

4-methoxycarbonylphenyl bromide
619-42-1

4-methoxycarbonylphenyl bromide

4-Brombenzoesaeure-n-octadecylester
70153-15-0

4-Brombenzoesaeure-n-octadecylester

Conditions
ConditionsYield
Stage #1: 1-octadecanol; 4-methoxycarbonylphenyl bromide In xylene for 0.5h; Heating;
Stage #2: With TiO(acac)2 In xylene for 5h; Heating;
99%
cycl-isopropylidene malonate
2033-24-1

cycl-isopropylidene malonate

1-octadecanol
112-92-5

1-octadecanol

Conditions
ConditionsYield
at 115℃; for 3h;99%
Stage #1: cycl-isopropylidene malonate; 1-octadecanol In toluene for 4h; Reflux;
Stage #2: With sodium hydrogencarbonate In water; toluene at 20℃;
Stage #3: With hydrogenchloride In water
96%
at 110 - 120℃; for 1h;93%
1-octadecanol
112-92-5

1-octadecanol

bis(trichloromethyl) carbonate
32315-10-9

bis(trichloromethyl) carbonate

stearyl chloroformate
51637-93-5

stearyl chloroformate

Conditions
ConditionsYield
With pyridine In tetrachloromethane at -15 - 40℃; Product distribution / selectivity;99%
With pyridine In dichloromethane at 10 - 15℃; for 2h; Cooling with ice;83%
Stage #1: bis(trichloromethyl) carbonate With potassium carbonate; N,N-dimethyl-formamide In toluene at 0℃; for 0.5h; Inert atmosphere;
Stage #2: 1-octadecanol In toluene at 0 - 20℃; for 12h; Inert atmosphere;
75%
With pyridine In tetrachloromethane at -20 - 20℃;
1-octadecanol
112-92-5

1-octadecanol

3-phenylpropanoic acid methyl ester
103-25-3

3-phenylpropanoic acid methyl ester

octadecyl 3-phenylpropionate
120703-15-3

octadecyl 3-phenylpropionate

Conditions
ConditionsYield
With Zn4(OCOCF3)6O In di-isopropyl ether for 18h; Heating;99%
With potassium phosphate; N-benzyl-N,N,N-triethylammonium chloride In toluene for 48h; Reflux;69%
1-octadecanol
112-92-5

1-octadecanol

(E)-3-phenylacrylic acid
140-10-3

(E)-3-phenylacrylic acid

octadecyl (2E)-3-phenylprop-2-enoate
61415-12-1

octadecyl (2E)-3-phenylprop-2-enoate

Conditions
ConditionsYield
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran at 20℃; Mitsunobu reaction;99%
1-octadecanol
112-92-5

1-octadecanol

(+-)-2-methyl-pent-4-enoic acid
1575-74-2

(+-)-2-methyl-pent-4-enoic acid

octadecyl 2-methylpent-4-enoate

octadecyl 2-methylpent-4-enoate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; Steglich Esterification;99%
1-octadecanol
112-92-5

1-octadecanol

octadecanoic acid, octadecyl ester
2778-96-3

octadecanoic acid, octadecyl ester

Conditions
ConditionsYield
With sodium bromate; sulfuric acid; sodium bromide In water at 20℃; for 24h;99%
With (bis[(2-diisopropylphosphino)ethyl]amine)Mn(CO)2 at 150℃; for 24h; Catalytic behavior; Inert atmosphere;80 %Spectr.
1-octadecanol
112-92-5

1-octadecanol

1,12-dodecanedioic acid
693-23-2

1,12-dodecanedioic acid

distearyl dodecanedioate
42234-06-0

distearyl dodecanedioate

Conditions
ConditionsYield
With 1-hexadecyl-3-sulfo-1H-imidazol-3-ium chloride In neat (no solvent) at 110℃; for 16h; Green chemistry;99%

1-Octadecanol Consensus Reports

1-OCTADECANOL is reported in EPA TSCA Inventory.

1-Octadecanol Specification

The IUPAC name of 1-Octadecanol is octadecan-1-ol. With the CAS registry number 112-92-5 and EINECS 204-017-6, it is also named as Stearyl alcohol. The product's categories are Industrial / Fine Chemicals; 1-Alkanols; Biochemistry; Higher Fatty Acids & Higher Alcohols; Monofunctional & alpha,omega-Bifunctional Alkanes; Monofunctional Alkanes; Saturated Higher Alcohols. It is white flakes which is soluble in alcohol, benzene, chloroform, insoluble in water. When heated to decomposition it emits acrid smoke and irritating fumes. Additionally, this chemical should be sealed in the container, avoided direct sunshine and stored in the cool and well-ventilated place.

The other characteristics of this product can be summarized as: (1)ACD/LogP: 8.31; (2)# of Rule of 5 Violations: 1; (3)ACD/LogD (pH 5.5): 8.31; (4)ACD/LogD (pH 7.4): 8.31; (5)#H bond acceptors: 1; (6)#H bond donors: 1; (7)#Freely Rotating Bonds: 17; (8)Polar Surface Area: 9.23 Å2; (9)Index of Refraction: 1.45; (10)Molar Refractivity: 86.97 cm3; (11)Molar Volume: 323.1 cm3; (12)Polarizability: 34.47×10-24 cm3; (13)Surface Tension: 31.4 dyne/cm; (14)Enthalpy of Vaporization: 66.88 kJ/mol; (15)Vapour Pressure: 9.11E-06 mmHg at 25°C; (16)Rotatable Bond Count: 16; (17)Exact Mass: 270.292266; (18)MonoIsotopic Mass: 270.292266; (19)Topological Polar Surface Area: 20.2; (20)Heavy Atom Count: 19; (21)Complexity: 145.

Preparation of 1-Octadecanol: It can be obtained from stearic acid by the process of catalytic hydrogenation.

Uses of 1-Octadecanol: It is used as an emollient, emulsifier, and thickener in ointments of various sorts, and is widely used as a hair coating in shampoos and hair conditioners. It is also used as an ingredient in lubricants, resins, perfumes and cosmetics. What's more, this chemical is used as a liquid solar blanket in swimming pools by forming a molecule thick layer on the surface of the water and slowing the evaporation rate of the pool water. In addition, it is used to produce 1-chloro-octadecane. This reaction needs reagent HCl at temperature of 140-150 °C.

People can use the following data to convert to the molecule structure. 
1. SMILES:OCCCCCCCCCCCCCCCCCC
2. InChI:InChI=1/C18H38O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19/h19H,2-18H2,1H3
3. InChIKey:GLDOVTGHNKAZLK-UHFFFAOYAZ

The following are the toxicity data which has been tested.

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rat LD50 oral 20gm/kg (20000mg/kg)   "Kirk-Othmer Encyclopedia of Chemical Technology," 3rd ed., Grayson, M., and D. Eckroth, eds. New York, John Wiley & Sons, Inc., 1978Vol. 1, Pg. 722, 1978.

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