• Name

  TRIS(HYDROXYPROPYL)PHOSPHINE

• EINECS
• CAS No. 4706-17-6
• Article Data4
• CAS DataBase
• Density 1.136 g/mL at 25 °C
• Solubility
• Melting Point
• Formula C₉H₂₁O₃P
• Boiling Point 196-198 °C(Press: 1 Torr)
• Molecular Weight 208.238
• Flash Point >110℃
• Transport Information UN 2924
• Appearance
• Safety 26-36/37/39
• Risk Codes 10-34
• Molecular Structure
• Hazard Symbols C
• Synonyms 1-Propanol,3,3',3''-phosphinidynetri- (6CI,8CI);Hishicolin P 500;Phosphine,tris(3-hydroxypropyl)-;Pirugon PP 40;Tris(3-hydroxypropyl)phosphine;Tris(hydroxypropyl)phosphine;
• PSA 74.28000
• LogP 0.61550

Synthetic route

acetic acid 3-[bis-(3-acetoxy-propyl)-phosphanyl]-propyl ester

A

4706-17-6

tris(3-hydroxypropyl)phosphine

B

51805-42-6

tris(3-hydroxypropyl)phosphane oxide

Conditions

Conditions	Yield
hydrolysis; Yield given; Yields of byproduct given;

107-18-6

allyl alcohol

phosphine

phosphine

A

4706-18-7

(3-Hydroxypropyl)phosphan

B

4706-16-5

bis-(3-hydroxy-propyl)-phosphine

C

4706-17-6

tris(3-hydroxypropyl)phosphine

Conditions

Conditions	Yield
im UV-Licht;

...Expand

107-18-6

allyl alcohol

A

4706-17-6

tris(3-hydroxypropyl)phosphine

B

bis-<3-hydroxy-propyl>-phosphine;3-phosphino-propan-1-ol

bis-<3-hydroxy-propyl>-phosphine;3-phosphino-propan-1-ol

Conditions

Conditions	Yield
With phosphan Irradiation.UV-Bestrahlung;

29269-17-8

trimethyl 3,3',3''-phosphanetriyltripropionate

4706-17-6

tris(3-hydroxypropyl)phosphine

Conditions

Conditions	Yield
With lithium aluminium tetrahydride In tetrahydrofuran at 0℃; for 4h;

3768-58-9

bis(dimethylamino)dimethylsilane

4706-17-6

tris(3-hydroxypropyl)phosphine

[(3-{bis-[3-(dimethylamino-dimethyl-silanyloxy)-propyl]-phosphanyl}-propoxy)-dimethyl-silanyl]-dimethyl-amine

Conditions

Conditions	Yield
In tetrahydrofuran	91%

109-69-3

n-Butyl chloride

4706-17-6

tris(3-hydroxypropyl)phosphine

butyltris(3-hydroxypropyl)phosphonium chloride

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 100℃; for 16h;	90%

4706-17-6

tris(3-hydroxypropyl)phosphine

106-51-4

p-benzoquinone

C15H25O5P

Conditions

Conditions	Yield
In acetone at 20℃; Inert atmosphere;	86%

4706-17-6

tris(3-hydroxypropyl)phosphine

1592-20-7

4-Vinylbenzyl chloride

tris(hydroxypropyl)(4-vinylbenzyl)phosphonium chloride

Conditions

Conditions	Yield
In acetonitrile at 80℃; for 24h; Inert atmosphere;	82%
In acetonitrile for 16h; Inert atmosphere; Heating;	79%

4706-17-6

tris(3-hydroxypropyl)phosphine

2880-58-2

2-methoxy-1,4-benzoquinone

C16H27O6P

Conditions

Conditions	Yield
In acetone at 20℃; Inert atmosphere;	81%

(η(5)-C5Me5)Ru(CO)2Cl

4706-17-6

tris(3-hydroxypropyl)phosphine

217815-52-6

(C5(CH3)5)RuCl(CO)(P((CH2)3OH)3)

Conditions

Conditions	Yield
In not given Irradiation (UV/VIS); Ar-atmosphere; in THF or MeOH/H2O, not specified; stirring and irradiating equimolar amts. for 1 h in quartz autoclave, then refluxing; solvent removal (vac.), chromy. (SiO2, ether, then ethyl acetate/MeOH=4:1), solvent removal (vac.), washing (H2O), drying, recrystn. (hot MePh); elem. anal.;	78%

4706-17-6

tris(3-hydroxypropyl)phosphine

20649-42-7, 458-36-6

coniferaldehyde

C19H31O6P

Conditions

Conditions	Yield
In acetone at 20℃; for 3h;	78%

4706-17-6

tris(3-hydroxypropyl)phosphine

1309945-96-7

tris(3-bromopropyl)phosphine

Conditions

Conditions	Yield
With phosphorus tribromide In dichloromethane at 20℃; for 18h;	73%
With phosphorus tribromide In dichloromethane at 20℃; for 18h; Inert atmosphere;	29%

4706-17-6

tris(3-hydroxypropyl)phosphine

4206-58-0, 87345-53-7

sinapinaldehyde

958644-05-8

C20H33O7P

Conditions

Conditions	Yield
In acetone at 20℃; for 3h;	70%

4706-17-6

tris(3-hydroxypropyl)phosphine

[(3-{bis-[3-(dimethylamino-dimethyl-silanyloxy)-propyl]-phosphanyl}-propoxy)-dimethyl-silanyl]-dimethyl-amine

3-[{3-[(3-{bis-[3-({3-[bis-(3-hydroxy-propyl)-phosphanyl]-propoxy}-dimethyl-silanyloxy)-propyl]-phosphanyl}-propoxy)-dimethyl-silanyloxy]-propyl}-(3-hydroxy-propyl)-phosphanyl]-propan-1-ol

Conditions

Conditions	Yield
In tetrahydrofuran

1-Propanol,3,3',3''-phosphinidynetris- Specification