1-Propanol supplier | CasNO.71-23-8

Name
1-Propanol
EINECS 200-746-9
CAS No. 71-23-8
Article Data946
CAS DataBase
Density 0.795 g/cm³
Solubility soluble in water
Melting Point -127 °C
Formula C₃H₈O
Boiling Point 95.784 °C at 760 mmHg
Molecular Weight 60.0959
Flash Point 15 °C
Transport Information UN 1274 3/PG 2
Appearance colourless liquid
Safety 7-16-24-26-39
Risk Codes 11-41-67
Molecular Structure
Hazard Symbols F, Xi
Synonyms Propylalcohol (8CI);1-Hydroxypropane;Ethylcarbinol;NSC 30300;Optal;Osmosolextra;Propanol;n-Propanol;n-Propyl alcohol;
PSA 20.23000
LogP 0.38870

Synthetic route

: 123-38-6
propionaldehyde

: 71-23-8
propan-1-ol

Conditions

Conditions	Yield
With hydrogen; mer-Os(PPh3)3HBr(CO) at 150℃; under 22800 Torr; for 1.66667h; Product distribution;	100%
With hydrogen; mer-Os(PPh3)3HBr(CO) In toluene at 150℃; under 22800 Torr; for 1.7h;	100%
With hydrogen In water at 60℃; under 15001.5 Torr; for 8h; Reagent/catalyst; Autoclave;	100%

: 107-18-6
allyl alcohol

: 71-23-8
propan-1-ol

Conditions

Conditions	Yield
With hydrogen; poly-1,2,3-triazolyl ferrocenyl dendrimer-Pd nanoparticle In methanol; chloroform at 25℃; under 760.051 Torr;	100%
With (1+)*OTf(1-); Gantrez 149; bis[(2-diphenylphosphino)ethyl]amine hydrochloride; hydrogen at 25℃; Mechanism; Product distribution; 1.) CH3CN, 10 h; 2.) H2O; var. Rh(I) complex cat., solvent;	95%
With <(Pd5Phen2)OAc>n; hydrogen In water at 30℃; Product distribution; hydogen and substrate concentration dependence;	90%

: 1333-74-0
hydrogen

: 107-18-6
allyl alcohol

: 71-23-8
propan-1-ol

Conditions

Conditions	Yield
With C61H62ClN3P2Ru In dichloromethane-d2 at 50℃; under 3040.2 Torr; for 10h; Reagent/catalyst; Time;	100%

: 624-48-6
dimethyl cis-but-2-ene-1,4-dioate

A: 109-99-9
tetrahydrofuran

B: 13436-45-8
2-methoxytetrahydrofuran

C: 96-48-0
4-butanolide

D: 71-23-8
propan-1-ol

E: 64001-06-5
2-(4'-hydroxybutoxy)-tetrahydrofuran

F: 110-63-4
Butane-1,4-diol

G: 71-36-3
butan-1-ol

Conditions

Conditions	Yield
With hydrogen; copper catalyst, T 4489, Sud-Chemie AG, Munich at 150 - 280℃; under 187519 Torr; Neat liquid(s) and gas(es)/vapour(s);	A 1% B n/a C 0.4% D n/a E n/a F 98% G 0.5%

...Expand

: 79-33-4
L-Lactic acid

: 71-23-8
propan-1-ol

Conditions

Conditions	Yield
With hydrogen In water at 119.84℃; under 60006 Torr; for 2h; Catalytic behavior; Reagent/catalyst; Autoclave; Sealed tube;	97%

: 802294-64-0
propionic acid

: 71-23-8
propan-1-ol

Conditions

Conditions	Yield
Stage #1: propionic acid With borane-2-methyltetrahydrofuran complex In 2-methyltetrahydrofuran at 0 - 20℃; for 2h; Stage #2: With water In 2-methyltetrahydrofuran Product distribution / selectivity;	96.5%
With hydrogen In water at 119.84℃; under 7500.75 - 60006 Torr; for 2h; Catalytic behavior; Reagent/catalyst; Autoclave; Sealed tube;	96%
With hydrogen In water at 100℃; under 37503.8 Torr; for 12h; Pressure; Reagent/catalyst; Autoclave;	94%

: 57-55-6
propylene glycol

: 71-23-8
propan-1-ol

Conditions

Conditions	Yield
With [C6H3-2,6-(OP(tBu)2)2]IrH2; trifluorormethanesulfonic acid; water; hydrogen In 1,4-dioxane at 125℃; under 5171.62 Torr; Temperature; Pressure; Solvent; Autoclave;	95%
With hydrogen In water at 210℃; under 30753.1 Torr; for 5h; Autoclave; Sealed tube;
With hydrogen In water at 179.84℃; under 37503.8 Torr; for 12h;	80 %Chromat.
at 315℃; Gas phase;

: 1-chloropropenol

: 71-23-8
propan-1-ol

Conditions

Conditions	Yield
With N-ethyl-N-hydroxy-ethanamine; sodium hydroxide In tert-butyl alcohol for 2h;	93%

: 53720-59-5
dipropyl phenylarsonate

: 100-39-0
benzyl bromide

A: 71-23-8
propan-1-ol

B: 106-94-5
propyl bromide

C: 75099-95-5
C16H19AsO3

Conditions

Conditions	Yield
at 150℃; for 1.5h;	A n/a B n/a C 91.7%

...Expand

: 57-55-6
propylene glycol

A: 71-23-8
propan-1-ol

B: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
With hydrogen at 180℃; under 37503.8 Torr; Catalytic behavior; chemoselective reaction;	A 91.2% B 7.8%
With hydrogen In water at 179.84℃; under 22502.3 Torr; for 10h; Autoclave;	A 76% B 9%
With hydrogen In water at 130℃; under 30003 Torr; for 24h;

: 56-81-5
glycerol

A: 71-23-8
propan-1-ol

B: 57-55-6
propylene glycol

Conditions

Conditions	Yield
In ethanol at 180℃; under 3750.38 Torr; for 24h; Inert atmosphere; Autoclave;	A 6% B 90%
With hydrogen at 210℃; under 33753.4 Torr; for 12h; Catalytic behavior; Reagent/catalyst; Temperature; Pressure;	A n/a B 51.3%
With hydrogen In 1,4-dioxane at 139.84℃; under 60006 Torr; for 24h;	A 34% B 18%

: 554-12-1
propanoic acid methyl ester

: 71-23-8
propan-1-ol

Conditions

Conditions	Yield
With (Ppyz)Zr(BH4)2Cl2 In diethyl ether for 4h; Heating;	90%
With isobutylmagnesium bromide; bis(cyclopentadienyl)titanium dichloride In diethyl ether for 1h; Ambient temperature; Yield given;
With hydrogen In water at 179.84℃; under 37503.8 Torr; for 6h;
With hydrogen In water at 150℃; under 37503.8 Torr; for 16h; Autoclave;	> 99 %Chromat.

: 15606-91-4
tripropyl arsenite

: 120-80-9
benzene-1,2-diol

A: 71-23-8
propan-1-ol

B: 66073-82-3
o-hydroxyphenylenoxybenzo-1,3,2-dioxaarsole

Conditions

Conditions	Yield
at 145 - 155℃;	A n/a B 90%

...Expand

: 107-19-7
propargyl alcohol

A: 71-23-8
propan-1-ol

B: 107-18-6
allyl alcohol

Conditions

Conditions	Yield
palladium anchored polystyrene In neat (no solvent) at 25℃; under 41371.8 Torr; for 15h;	A 5% B 90%
With hydrogen; copper-palladium; silica gel In ethanol at 25℃; under 760 Torr; Kinetics;	A n/a B 85%
With hydrogen; palladium dichloride In N,N-dimethyl-formamide under 18751.5 Torr; for 0.316667h; Product distribution; Ambient temperature; various time;	A 2.6% B 76.3%

: 107-10-8
propylamine

: 100-52-7
benzaldehyde

: 98-86-2
acetophenone

A: 71-23-8
propan-1-ol

B: 580-35-8
2,4,6-triphenylpyridine

Conditions

Conditions	Yield
With diphenylammonium trifluoromethanesulfonate at 120℃; for 4.5h; Neat (no solvent); regioselective reaction;	A 85 %Chromat. B 89%

...Expand

: 623-43-8, 4358-59-2, 18707-60-3, 130981-57-6
methyl crotonate

: 71-23-8
propan-1-ol

Conditions

Conditions	Yield
With sodium tetrahydroborate; C36H30F6N10Ni4O10(2+)*2C2F3O2(1-); zinc(II) chloride In tetrahydrofuran at 45℃; for 12h;	89%

: 302-17-0
chloral hydrate

: 16196-02-4
phenyl phosphinic acid dipropyl ester

A: 71-23-8
propan-1-ol

B: 1235818-82-2
C11H14Cl3O3P

Conditions

Conditions	Yield
In benzene at 30 - 40℃; Abramov reaction; Inert atmosphere;	A n/a B 88%

...Expand

: 56-81-5
glycerol

A: 71-23-8
propan-1-ol

B: 74-98-6
propane

Conditions

Conditions	Yield
With hydrogen In 1,4-dioxane at 159.84℃; under 60006 Torr; for 24h; Autoclave;	A 87% B 9%
With [Ru(OH2)3(4'-phenyl-2,2':6',2''-terpy)](OTf)2; hydrogen; ortho-tungstic acid In water at 250℃; under 41254.1 Torr; for 24h;	A 39 %Chromat. B 52 %Chromat.
With hydrogen In water at 200℃; under 18751.9 Torr; for 16h; Autoclave;

: 503-66-2
3-hydroxypropionic acid

A: 71-23-8
propan-1-ol

B: 110-63-4
Butane-1,4-diol

Conditions

Conditions	Yield
With hydrogen In water at 100℃; under 37503.8 Torr; for 30h; Pressure; Reagent/catalyst; Autoclave;	A 10% B 85%

: 56-81-5
glycerol

A: 71-23-8
propan-1-ol

B: 57-55-6
propylene glycol

C: 107-21-1
ethylene glycol

Conditions

Conditions	Yield
In isopropyl alcohol at 180℃; under 3750.38 Torr; for 12h; Inert atmosphere; Autoclave;	A 6% B 84% C 6%
With hydrogen In water at 200℃; under 60006 Torr; for 18h; Reagent/catalyst; Autoclave;
With iridium on carbon; hydrogen In water at 200℃; under 37503.8 Torr; for 4h;
With hydrogen In water at 200℃; under 18617.8 Torr; for 12h; Catalytic behavior; Reagent/catalyst; Autoclave;
With hydrogen In water at 220℃; under 60006 Torr; for 120h; Catalytic behavior; Reagent/catalyst; Autoclave;

...Expand

: 1245613-12-0
4-benzyloxycarbonylaminobutyric acid propyl ester

A: 71-23-8
propan-1-ol

B: 5105-78-2
4-(benzyloxycarbonylamino)butyric acid

Conditions

Conditions	Yield
With methanol; Bacillus subtilis esterase In hexane at 37℃; for 0.5h; pH=7.4; Kinetics; Reagent/catalyst; Time; aq. phosphate buffer; Enzymatic reaction;	A n/a B 83%

: 96-48-0
4-butanolide

A: 109-99-9
tetrahydrofuran

B: 71-23-8
propan-1-ol

C: 110-63-4
Butane-1,4-diol

D: 107-92-6
butyric acid

E: 71-36-3
butan-1-ol

Conditions

Conditions	Yield
With hydrogen; 5% platinum on alumina at 250℃; under 152000 Torr; Product distribution; var. catalysts;	A 82.3% B 1% C 4.8% D 1.2% E 1%

...Expand

: 99948-03-5
2,2-pentamethylene-3-(trimethylsilyl)-5-propyl-2,5-dihydrofuran

A: 71-23-8
propan-1-ol

B: 99948-11-5
5,5-pentamethylene-4-(trimethylsilyl)-2(5H)-furanone

Conditions

Conditions	Yield
With oxygen for 72h; Ambient temperature;	A n/a B 82%

: 624-48-6
dimethyl cis-but-2-ene-1,4-dioate

A: 109-99-9
tetrahydrofuran

B: 13436-45-8
2-methoxytetrahydrofuran

C: 96-48-0
4-butanolide

D: 71-23-8
propan-1-ol

E: 1-methoxy-1,4-butanediol

F: 64001-06-5
2-(4'-hydroxybutoxy)-tetrahydrofuran

G: 4-hydroxy-butanoic acid 4-hydroxybutyl ester

H: 110-63-4
Butane-1,4-diol

I: 25714-71-0
4-hydroxybutyraldehyde

J: 925-57-5
methyl 4-hydroxybutanoate

K: 71-36-3
butan-1-ol

Conditions

Conditions	Yield
With hydrogen at 190℃; under 46504.7 Torr; Gas phase;	A 5.3% B n/a C 10.4% D n/a E n/a F n/a G n/a H 79.1% I n/a J n/a K n/a

...Expand

: 503-66-2
3-hydroxypropionic acid

A: 71-23-8
propan-1-ol

B: 504-63-2
trimethyleneglycol

Conditions

Conditions	Yield
With ruthenium-carbon composite; hydrogen In water at 119.84℃; under 7500.75 - 60006 Torr; for 2h; Catalytic behavior; Autoclave; Sealed tube;	A 18% B 79%

: 110-63-4
Butane-1,4-diol

A: 96-48-0
4-butanolide

B: 71-23-8
propan-1-ol

C: 71-36-3
butan-1-ol

Conditions

Conditions	Yield
With ZnCuO2; hydrogen at 260℃; under 750.075 Torr;	A 77.2% B 6.7% C 5.3%

...Expand

: (C5H4CH3)2MoH3(1+)*O3SC6H4CH3(1-)={(C5H4CH3)2MoH3}(O3SC6H4CH3)

: 107-18-6
allyl alcohol

A: 71-23-8
propan-1-ol

B: {bis(η5-methylcyclopentadienyl)(η3-allyl)molybdenum(IV)} tosylate

C: 1333-74-0
hydrogen

Conditions

Conditions	Yield
N2 or Ar atmosphere or vac.; stirring (50°C);	A 19% B 76% C 77%

...Expand

: 106-36-5
propyl propionate

: 71-23-8
propan-1-ol

Conditions

Conditions	Yield
With C18H28Br2N4Ru; potassium tert-butylate; hydrogen In 1,4-dioxane at 105℃; under 22502.3 Torr; for 8h;	77%
Stage #1: propyl propionate With iron (II) stearate; ethylenediamine In toluene at 20℃; for 0.0833333h; Inert atmosphere; Schlenk technique; Stage #2: In toluene at 100℃; for 20h; Inert atmosphere; Schlenk technique;	75 %Chromat.
With [bis({2‐[bis(propan‐2‐yl)phosphanyl]ethyl})amine](borohydride)(carbonyl)(hydride)iron(II); hydrogen In tetrahydrofuran at 120℃; under 22502.3 Torr; for 19h; Autoclave;	68 %Chromat.

: 71-23-8
propan-1-ol

: 187737-37-7
propene

Conditions

Conditions	Yield
With mesoporous silica MCM-4l/Al at 349.84℃; for 50h;	100%
aluminum oxide at 375℃; under 6000.6 Torr;	99%
With HZSM-5zeolite with a SiO2/Al2O3 at 250℃; Reagent/catalyst; Inert atmosphere;	99%

: 71-23-8
propan-1-ol

: 513-08-6
phosphoric acid tripropyl ester

Conditions

Conditions	Yield
With oxygen; phosphan; copper dichloride at 24.9℃; Rate constant; Product distribution; other acohols and reagents, var. concentration of reagents and temperatures;	100%
With oxygen; phosphan; copper dichloride at 24.9℃;	100%
With trichlorophosphate In acetone at 10 - 30℃; under 10 Torr; for 4h;	97%

: 71-23-8
propan-1-ol

: 802294-64-0
propionic acid

Conditions

Conditions	Yield
With ammonium cerium (IV) nitrate; sodium trimethylsilylpropionate-d4; C18H22N4O2Ru(2+)*2F6P(1-); water at 20℃; for 0.5h;	100%
With sodium hydroxide; oxygen; lead acetate; palladium on activated charcoal In water at 150℃; under 7600 Torr; for 1h;	90.3%
With potassium phosphate; carbon dioxide; CrH6Mo6O24(3-)3H3N3H(1+) In dimethyl sulfoxide at 80℃; under 750.075 Torr; for 24h; Green chemistry;	90%

: 71-23-8
propan-1-ol

: 124-63-0
methanesulfonyl chloride

: 1912-31-8
propyl methanesulfonate

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 0 - 20℃; for 1h;	100%
With pyridine 1.) from -20 deg C to 30 deg C, 2.) room temp., 2 h;	65%
With pyridine at 0℃;

: 71-23-8
propan-1-ol

: 5381-98-6
2-chloro-2-oxo-2λ5-benzo[1,3,2]dioxaphosphorin-4-one

: 1-n-propoxy-4,5-benz-2,6-dioxaphosphorinanone-(3) 1-oxide

Conditions

Conditions	Yield
With pyridine In benzene for 2h; Ambient temperature;	100%

: 71-23-8
propan-1-ol

: 628-92-2
Cycloheptene

: 134986-44-0
(1R,2R)-1-Iodo-2-propoxy-cycloheptane

Conditions

Conditions	Yield
With ammonium cerium(IV) nitrate; iodine for 8h; Heating;	100%

: 71-23-8
propan-1-ol

: 501-97-3
4-hydroxyphenylpropionic acid

: 83281-52-1
3-(4-hydroxyphenyl)propionic acid propyl ester

Conditions

Conditions	Yield
With chloro-trimethyl-silane at 25℃; for 24h;	100%
With 3 A molecular sieve; sulfuric acid for 72h; Heating;
With hydrogenchloride Heating;
With chloro-trimethyl-silane at 25℃; for 24h;

: 71-23-8
propan-1-ol

: 54107-24-3
3-(2-vinyloxyethoxy)-1,2-propylene carbonate

: 126867-29-6
4-[2-(1-Propoxy-ethoxy)-ethoxymethyl]-[1,3]dioxolan-2-one

Conditions

Conditions	Yield
With heptafluorobutyric Acid at 20 - 45℃; for 0.333333h;	100%

: 71-23-8
propan-1-ol

: 13407-35-7, 25531-84-4, 25531-87-7, 25531-89-9, 25531-90-2, 92620-18-3, 130193-64-5
(2R,3R,4S,5S)-2,3,4,5-Tetrahydroxy-piperidine-1-carboxylic acid benzyl ester

: (+/-)(3α,4α,5β)-1-propylpiperidine-3,4,5-triol

Conditions

Conditions	Yield
With hydrogen; acetic acid; palladium on activated charcoal In methanol for 0.5h; Ambient temperature;	100%

: 71-23-8
propan-1-ol

: 2-phenyl-3-hexylamine

: N-n-propylidene-2-phenyl-3-hexylamine

Conditions

Conditions	Yield
With magnesium sulfate In dichloromethane	100%

: 71-23-8
propan-1-ol

: 159574-04-6
(2R,4R)-(-)-6-fluoro-2,3-dihydro-2',5'-dioxospiro<4H-1-benzopyran-4,4'-imidazolidine>-2-carboxylic acid

: 156039-36-0
(2R,4R)-6-fluoro-2,3-dihydro-2',5'-dioxospiro<4H-1-benzopyran-4,4'-imidazolidine>-2-carboxylic acid n-propyl ester

Conditions

Conditions	Yield
sulfuric acid In benzene for 5h; Heating;	100%

: 71-23-8
propan-1-ol

: 6972-27-6
1,3-Dimethyl-6-chlorouracil

: 93767-18-1
1,3-Dimethyl-6-propoxy-1H-pyrimidine-2,4-dione

Conditions

Conditions	Yield
With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride In dichloromethane; water for 2h; Ambient temperature;	100%

: 71-23-8
propan-1-ol

: 103-71-9
phenyl isocyanate

: 63379-16-8
1-propyl (4-methylphenyl)carbamate

Conditions

Conditions	Yield
In pyridine; ethyl acetate	100%

: 71-23-8
propan-1-ol

: 16540-32-2
2-ethyl-1,2-oxaphospholan-5-one 2-oxide

: 19935-02-5
3-(ethylpropoxyphosphinyl)propionic acid

Conditions

Conditions	Yield
at 20 - 34℃;	100%

: 71-23-8
propan-1-ol

: 16540-32-2
2-ethyl-1,2-oxaphospholan-5-one 2-oxide

: propyl 3-(ethylhydroxyphosphinyl)propionate

Conditions

Conditions	Yield
at 0 - 15℃;	100%

: 71-23-8
propan-1-ol

: 64481-53-4
N,N'-dibenzyl-2,3,5,6-piperazinetetraone

: 76952-16-4
1,3-Dibenzyl-2-hydroxy-4,5-dioxo-imidazolidine-2-carboxylic acid propyl ester

Conditions

Conditions	Yield
for 6h; Heating;	100%

: 71-23-8
propan-1-ol

: 7361-80-0
9,12,15-octadecatrienoic acid methyl ester

: (9E,12E,15Z)-Octadeca-9,12,15-trienoic acid propyl ester

Conditions

Conditions	Yield
With chloro-trimethyl-silane for 2h; Heating;	100%

: 71-23-8
propan-1-ol

: 176501-96-5
N,N′-dinitrourea

: propyl nitrocarbamate

Conditions

Conditions	Yield
Heating;	100%

: 71-23-8
propan-1-ol

: 99056-35-6
ethyl 4,7-dihydro-2-methyl-7-oxopyrazolo[1,5-a]pyrimidine-6-carboxylate

: propyl 2-methyl-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-6-carboxylate

Conditions

Conditions	Yield
With titanium(IV) isopropylate Heating;	100%

: 71-23-8
propan-1-ol

: 168273-06-1
rimonabant

: 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)pyrazole-3-carboxamide n-propanol solvate

Conditions

Conditions	Yield
at 4 - 20℃; Heating / reflux;	100%
at 5 - 50℃; for 5h;

: 71-23-8
propan-1-ol

: 335148-89-5
bisphenol AF bisoxalyl chloride adduct

: bisphenol-AF bis(propyl oxalate)

Conditions

Conditions	Yield
In dichloromethane at -35 - 20℃; for 3h; Cooling with isopropanol/dry ice/water;	100%

: 71-23-8
propan-1-ol

: Al((CH3)2CHO)4(1-)*Ta(OCH(CH3)2)6(1-)*Cu(2+)={((CH3)2CHO)4Al}Cu{Ta(OCH(CH3)2)6}

: Al(C3H7O)4(1-)*Ta(C3H7O)6(1-)*Cu(2+)={(C3H7O)4Al}Cu{Ta(C3H7O)6}

Conditions

Conditions	Yield
In benzene excess of alcohol, stirring, reflux (20h); evapn. under a pressure of 0.3 mm (room temp.), drying at 50-60°C, elem. anal.;	100%

: 71-23-8
propan-1-ol

: 69-65-8
mannitol

: 11113-50-1
boric acid

: 1,2,3,4,5,6-hexakis-O-dipropoxyboryl-D-mannitol

Conditions

Conditions	Yield
In toluene boiling a mixt. of D-mannitol, H3BO3, and n-propanol in toluene on a Dean-Stark apparatus (azeotropic removal of H2O);; removal of toluene and propanol; elem. anal.;;	100%

...Expand

: 71-23-8
propan-1-ol

: 1169854-26-5
C30H35N3O2

: 1169855-96-2
C33H41N3O2

Conditions

Conditions	Yield
With hydrogenchloride In 1,4-dioxane at 100℃; for 3h; Sealed tube;	100%

: 6118-51-0
exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride

: 71-23-8
propan-1-ol

: 7-oxa-bicyclo[2,2,1]heptane-2,3-dicarboxylic acid monopropyl ester

Conditions

Conditions	Yield
With palladium 10% on activated carbon; hydrogen at 50℃; under 37503.8 Torr;	100%

: 71-23-8
propan-1-ol

: 16526-68-4
cis-1,3,5-cyclohexane tricarboxylic acid

: 107383-91-5
cis,cis-tri-n-propyl cyclohexane-1,3,5-tricarboxylate

Conditions

Conditions	Yield
With hydrogenchloride for 3h; Reflux;	100%

: 71-23-8
propan-1-ol

: 102987-96-2
2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl isoselenocyanate

: 1434818-14-0
O-n-propyl-N-(2,3,4,6-tetra-O-acetyl-β-d-glucopyranosyl)selenocarbamate

Conditions

Conditions	Yield
at 70℃; for 2h; Inert atmosphere; Darkness;	100%

1-Propanol Specification

The 1-Propanol, with the CAS registry number 71-23-8,is also known as Propan-1-ol; Propyl alcohol. It belongs to the product categories of Carbon Steel Flex-Spout Cans;Semi-Bulk Solvents.Its EINECS number is 200-746-9. This chemical's molecular formula is C₃H₈O and molecular weight is 60.10. What's more,Its systematic name is 1-Propanol.It is a colorless liquid made by oxidation of aliphatic hydrocarbons that is used as a solvent and chemical intermediate.It may form peroxides in contact with air.And it is incompatible with alkali metals, alkaline earths, aluminium, oxidizing agents, nitro compounds,highly flammable.And it is used as a solvent in the pharmaceutical industry, and for resins and cellulose esters.

Physical properties about 1-Propanol are:
(1)ACD/LogP: 0.329; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.33; (4)ACD/LogD (pH 7.4): 0.33; (5)ACD/BCF (pH 5.5): 1.05; (6)ACD/BCF (pH 7.4): 1.05; (7)ACD/KOC (pH 5.5): 35.97; (8)ACD/KOC (pH 7.4): 35.97; (9)#H bond acceptors: 1; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 2; (12)Index of Refraction: 1.38; (13)Molar Refractivity: 17.482 cm³; (14)Molar Volume: 75.562 cm³; (15)Surface Tension: 24.576000213623 dyne/cm; (16)Density: 0.795 g/cm³; (17)Flash Point: 15 °C; (18)Enthalpy of Vaporization: 41.44 kJ/mol; (19)Boiling Point: 95.784 °C at 760 mmHg; (20)Vapour Pressure: 26.3169994354248 mmHg at 25°C.

You can still convert the following datas into molecular structure:
(1)SMILES:CCCO;
(2)Std. InChI:InChI=1S/C3H8O/c1-2-3-4/h4H,2-3H2,1H3;
(3)Std. InChIKey:BDERNNFJNOPAEC-UHFFFAOYSA-N.

Preparation of 1-Propanol:
It is a major constituent of fusel oil, a by-product formed from certain amino acids when potatoes or grains are fermented to produce ethanol.
It is manufactured by catalytic hydrogenation of propionaldehyde. The propionaldehyde is itself produced via the oxo process, by hydroformylation of ethylene using carbon monoxide and hydrogen in the presence of a catalyst such as cobalt octacarbonyl or a rhodium complex.
H₂C=CH₂ + CO + H₂ → CH₃CH₂CH=O
CH₃CH₂CH=O + H₂ → CH₃CH₂CH₂OH
A traditional laboratory preparation of 1-propanol involves treating n-propyl iodide with moist Ag₂O.

Safety Information of 1-Propanol:
The 1-Propanol is extremely irritating when contact with eyes and may cause burns.The vapors irritate nose and throat. In high concentrations, it may cause nausea, dizziness, headache, and stupor.So we should keep container tightly closed and away from heat. When you use it ,wear eye/face protection and avoid contact with skin. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

The toxicity data of 1-Propanol as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LDLo	intravenous	4008mg/kg (4008mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 16, Pg. 1, 1920.
dog	LDLo	oral	3gm/kg (3000mg/kg)	BLOOD: HEMORRHAGE GASTROINTESTINAL: OTHER CHANGES	Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 81, Pg. 192, 1875.
dog	LDLo	subcutaneous	4gm/kg (4000mg/kg)	BLOOD: HEMORRHAGE GASTROINTESTINAL: OTHER CHANGES	Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 81, Pg. 192, 1875.
guinea pig	LD50	intraperitoneal	1208mg/kg (1208mg/kg)		EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
hamster	LD50	intraperitoneal	2338mg/kg (2338mg/kg)		EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
mammal (species unspecified)	LDLo	subcutaneous	5gm/kg (5000mg/kg)	LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BEHAVIORAL: GENERAL ANESTHETIC	Archiv fuer Toxikologie. Vol. 16, Pg. 84, 1956.
mouse	LC50	inhalation	48gm/m3 (48000mg/m3)		Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 18(3), Pg. 48, 1974.
mouse	LD50	intraperitoneal	3125mg/kg (3125mg/kg)		EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
mouse	LD50	intravenous	697mg/kg (697mg/kg)		EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
mouse	LD50	oral	6800mg/kg (6800mg/kg)		Proceedings of the European Society for the Study of Drug Toxicity. Vol. 9, Pg. 276, 1968.
mouse	LD50	subcutaneous	4700mg/kg (4700mg/kg)		Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971.
rabbit	LD50	intraperitoneal	515mg/kg (515mg/kg)		EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
rabbit	LD50	intravenous	483mg/kg (483mg/kg)		EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
rabbit	LD50	oral	2825mg/kg (2825mg/kg)		Industrial Medicine and Surgery. Vol. 41, Pg. 31, 1972.
rabbit	LD50	skin	5040mg/kg (5040mg/kg)		AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 10, Pg. 61, 1954.
rabbit	LDLo	subcutaneous	3gm/kg (3000mg/kg)		"Zur Pharmakologie Ungesattigter Alkohole, Dissertation," Bock, H., Pharmakologischen Institu der Universitat Breslau, Poland, 1930Vol. -, Pg. -, 1930.
rabbit	LDLo	unreported	4500mg/kg (4500mg/kg)		Therapeutische Monatshefte. Vol. 6, Pg. 327, 1892.
rat	LCLo	inhalation	4000ppm/4H (4000ppm)		AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 10, Pg. 61, 1954.
rat	LD50	intraperitoneal	2164mg/kg (2164mg/kg)		EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
rat	LD50	intravenous	590mg/kg (590mg/kg)		EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
rat	LD50	oral	1870mg/kg (1870mg/kg)		AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 10, Pg. 61, 1954.
women	LDLo	oral	5700mg/kg (5700mg/kg)	LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES CARDIAC: OTHER CHANGES	Archiv fuer Toxikologie. Vol. 16, Pg. 84, 1956.

Product Name

1-Propanol

Synthetic route

1-Propanol Specification

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