Products

Refine

Country

Business Type

Certificate

Display

Xi'an Quanao Biotech Co., Ltd.

Xi’an Quanao Biotech Co., Ltd. with 18 years experience in plant extract filed. Product grade: Medicine, Health care product, Cosmetics, Food, Beverage, Feed. Hot selling market: Europe, North America, South America, Middle East, Asia Pacifi

2021 New Product 99% Dextromethorphan / Methorphan Powder price cas:125-71-3

Cas:125-71-3

Min.Order:1 Kilogram

FOB Price: $99.0 / 158.0

Type:Manufacturers

inquiry

Kono Chem Co.,Ltd

Dextromethorphan [NO. 125-71-3] CAS [product name] Chinese dextromethorphan [product name] Dextromethorphan [product] effect of dextromethorphan as antitussive, [indications] cough caused by upper respiratory tract infection

Hot Selling Dextromethorphan in Bulk Supply

Cas:125-71-3

Min.Order:1 Kilogram

FOB Price: $360.0 / 380.0

Type:Other

inquiry

Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality Dextromethorphan

Cas:125-71-3

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

Hubei DiBo chemical co., LTD

Name:dextromethorphan CAS NO:125-71-3 Grade:For chemical industry, scientific research and export Product Quality 12 years of chemical raw materials Mature operation of the industry System stability Data storage Security without vulnerability

dextromethorphan CAS:125-71-3 Chinese manufacturers high-quality

Cas:125-71-3

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Dextromethorphan/ LIDE PHARMA- Factory supply / Best price

Cas:125-71-3

Min.Order:1 Gram

FOB Price: $0.9 / 1.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. High quality and competitive price: 1) Standard: BP/USP/EP/ enterprise standard 2) All purity 鈮 9% 3) We are manufacturers and can provide high quality products at factory prices. 2. Fast and safe delivery 1) The package can

Purity 99% Pharmaceutical Grade CAS 125-71-3 Dxm Dextromethorphan Powder

Cas:125-71-3

Min.Order:1 Metric Ton

FOB Price: $5.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 125-71-3 with competitive price

Cas:125-71-3

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by email in time prod

2021 New Product 99% Dextromethorphan / Methorphan Powder price cas:125-71-3

Cas:125-71-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best s

99% DEXTROMETHORPHAN CAS:125-71-3

Cas:125-71-3

Min.Order:10 Gram

Negotiable

Type:Other

inquiry

Qingdao Beluga Import and Export Co., LTD

Dextromethorphan CAS:125-71-3 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermedi

Dextromethorphan CAS:125-71-3

Cas:125-71-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Lonwin Chemical Group Limited

DEXTROMETHORPHAN CAS: 125-71-3 Specification Boiling point 414.48°C (rough estimate) density 1.0115 (rough estimate) refractive index 1.5740 (estimate) Fp 9℃ storage temp. 20°

Factory supply DEXTROMETHORPHAN

Cas:125-71-3

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Morphinan,3-methoxy-17-methyl-, (9α,13α,14α)-

Cas:125-71-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

Dextromethorphan

Cas:125-71-3

Min.Order:1 Kilogram

FOB Price: $1.0 / 100000.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white crystalline powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:as per your request Application:Respiratory System Agents Transportati

DEXTROMETHORPHAN

Cas:125-71-3

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Hefei Zhaobo Technology Co., Ltd.

Dextromethorphan CAS 125-71-3 Purity: 99% Min Application: Intermediates Appearance: Powder Package: Bag Delivery: 3-5days Our Advantage & Service 1.Top quality: Using high quality material and establishing a strict quality control s

Dextromethorphan CAS 125-71-3

Cas:125-71-3

Min.Order:1 Kilogram

FOB Price: $10.0 / 50.0

Type:Trading Company

inquiry

Shaanxi New nine Material Technology Co., Ltd.

Our Advantage & Service 1.Top quality: Using high quality material and establishing a strict quality control system,assigning specific persons in charge of each part of production,from raw material purchase to assembly. 2 Professional R&D

2021 New Product 99% Dextromethorphan / Methorphan Powder price cas:125-71-3

Cas:125-71-3

Min.Order:10 Gram

FOB Price: $5.0 / 7.0

Type:Trading Company

inquiry

Binbo Biological Co., Ltd

1.high purity 2.consistent quality 3.competitive price 4.fast shipping Binbo Biological Products Co. Ltd., is a professional high-tech enterprise which engaged in Biological products and raw materials. Binbo is engaged in R&D with perfect eq

Dextromethorphan CAS 125-71-3

Cas:125-71-3

Min.Order:1 Kilogram

FOB Price: $10.0 / 100.0

Type:Lab/Research institutions

inquiry

TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

DEXTROMETHORPHAN

Cas:125-71-3

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providing h

Factory Supply dextromethorphan

Cas:125-71-3

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate. In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so o

TIANFU CHEM DEXTROMETHORPHAN

Cas:125-71-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: N-Methyl-3-Methoxy-Morphinan CAS No.: 125-71-3 Molecule Formula:C18H25NO Molecule Weight:271.40 Purity: 99.0% Package: 25kg/drum Description:White powder Manufacture Standards:Enterprise Standard TESTING ITEMS

Lower Price N-Methyl-3-Methoxy-Morphinan on stock

Cas:125-71-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

DEXTROMETHORPHAN

Cas:125-71-3

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

DEXTROMETHORPHAN

Cas:125-71-3

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

DEXTROMETHORPHAN

Cas:125-71-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service an

Dextromethorphan

Cas:125-71-3

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

Dextromethorphan

Cas:125-71-3

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

healthtide biotech co.,ltd

Our advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be

Sell hot Dextromethorphan CAS 125-71-3

Cas:125-71-3

Min.Order:1 Gram

FOB Price: $1.0

Type:Trading Company

inquiry

Sinoway Industrial Co., Ltd.

Why is SINOWAY:1) Specialized in pharmaceutical and healthcare industrial since 19872) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days.4) We have warehouse in USA with quickly shipment . Application:API

99% up by HPLC Dextromethorphan 125-71-3

Cas:125-71-3

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

dextromethorphan

Cas:125-71-3

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM is one of China's leading providers of integrated fine chemical services including offering, research and development, Custom manufacturing business, as well as other Value-added customer services, for diversified range products of chemicals

DEXTROMETHORPHAN

Cas:125-71-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

dextromethorphan hydrobromide

dextromethorphan hydrobromide

dextromethorphan
125-71-3

dextromethorphan

Conditions
ConditionsYield
With sodium hydroxide In water pH=10; Inert atmosphere;100%
With ammonia In chloroform; water at 20℃; for 1h;
With ammonia In methanol at 20℃; for 1h;
With sodium hydroxide In water
In chloroform at 20℃; for 1h;2.88 g
dextromethorphan hydrobromide, monohydrate
6700-34-1

dextromethorphan hydrobromide, monohydrate

dextromethorphan
125-71-3

dextromethorphan

Conditions
ConditionsYield
With sodium hydroxide In chloroform; water for 0.5h;97.98%
dextromethorphan N-oxide hydrochloride
113951-04-5

dextromethorphan N-oxide hydrochloride

B

dextromethorphan
125-71-3

dextromethorphan

Conditions
ConditionsYield
Stage #1: dextromethorphan N-oxide hydrochloride With ferrocene In chloroform at 40℃; for 72h;
Stage #2: With sodium hydroxide In chloroform; water
A 92%
B 8%
With ferrocene In chloroform at 40℃; for 40h; Polonovski reaction; Inert atmosphere;A 92%
B 8%
(+)-2-methyl-1-(4-methoxy)benzyl-1,2,3,4,5,6,7,8-hexahydroisoquinoline
67596-84-3

(+)-2-methyl-1-(4-methoxy)benzyl-1,2,3,4,5,6,7,8-hexahydroisoquinoline

dextromethorphan
125-71-3

dextromethorphan

Conditions
ConditionsYield
With aluminum (III) chloride In dichloromethane at 20℃; for 2h; Reagent/catalyst;91%
rac-3-methoxy-17-methyl-morphinane
125-70-2, 125-71-3, 510-53-2, 3561-92-0

rac-3-methoxy-17-methyl-morphinane

dextromethorphan
125-71-3

dextromethorphan

Conditions
ConditionsYield
Gewinnung mit Hilfe von Lg-Weinsaeure;
Gewinnung mit Hilfe von Lg-Weinsaeure;
(9α,13α,14α)-3-methoxy-17-methylmorphinan-10-one
57969-05-8

(9α,13α,14α)-3-methoxy-17-methylmorphinan-10-one

A

dextromethorphan
125-71-3

dextromethorphan

B

ent-3-methoxy-17-methyl-morphinan-10β-ol
133443-97-7

ent-3-methoxy-17-methyl-morphinan-10β-ol

Conditions
ConditionsYield
With lithium aluminium tetrahydride; diethyl ether
(+)-3-methoxy-N-formylmorphinan
28973-48-0

(+)-3-methoxy-N-formylmorphinan

dextromethorphan
125-71-3

dextromethorphan

trimethylphenylammonium hydroxide
1899-02-1

trimethylphenylammonium hydroxide

ent-17-methyl-morphinan-3-ol

ent-17-methyl-morphinan-3-ol

dextromethorphan
125-71-3

dextromethorphan

Conditions
ConditionsYield
With methanol; toluene
With methanol; toluene
4-Methoxyphenylacetic acid
104-01-8

4-Methoxyphenylacetic acid

dextromethorphan
125-71-3

dextromethorphan

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 5 h / 150 °C
2: POCl3 / benzene / Heating
3: pyridine; tetrahydrofuran / 8 h / 0 °C
4: H2 / Ru(OCOCF3)2<(S)-tolbinap> / methanol / 100 h / 30 °C / 76000.1 Torr
View Scheme
Multi-step reaction with 5 steps
1.1: diisopropyl-carbodiimide; dmap / dichloromethane / 10 h / 0 - 20 °C
2.1: trichlorophosphate / toluene / 4 h / Reflux
3.1: phenylsilane; pyrrolidine / tetrahydrofuran; methanol / 5 h / 20 °C / Inert atmosphere
4.1: methanol / 0.25 h
4.2: 10 h / 20 °C
5.1: aluminum (III) chloride / dichloromethane / 2 h / 20 °C
View Scheme
1-(4-methoxybenzyl)-3,4,5,6,7,8-hexahydro-isoquinoline
51072-35-6

1-(4-methoxybenzyl)-3,4,5,6,7,8-hexahydro-isoquinoline

dextromethorphan
125-71-3

dextromethorphan

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: pyridine; tetrahydrofuran / 8 h / 0 °C
2: H2 / Ru(OCOCF3)2<(S)-tolbinap> / methanol / 100 h / 30 °C / 76000.1 Torr
View Scheme
Multi-step reaction with 3 steps
1.1: phenylsilane; pyrrolidine / tetrahydrofuran; methanol / 5 h / 20 °C / Inert atmosphere
2.1: methanol / 0.25 h
2.2: 10 h / 20 °C
3.1: aluminum (III) chloride / dichloromethane / 2 h / 20 °C
View Scheme
N-(2-cyclohex-1-enylethyl)-2-(4-methoxyphenyl)-acetamide
51072-34-5

N-(2-cyclohex-1-enylethyl)-2-(4-methoxyphenyl)-acetamide

dextromethorphan
125-71-3

dextromethorphan

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: POCl3 / benzene / Heating
2: pyridine; tetrahydrofuran / 8 h / 0 °C
3: H2 / Ru(OCOCF3)2<(S)-tolbinap> / methanol / 100 h / 30 °C / 76000.1 Torr
View Scheme
Multi-step reaction with 4 steps
1.1: trichlorophosphate / toluene / 4 h / Reflux
2.1: phenylsilane; pyrrolidine / tetrahydrofuran; methanol / 5 h / 20 °C / Inert atmosphere
3.1: methanol / 0.25 h
3.2: 10 h / 20 °C
4.1: aluminum (III) chloride / dichloromethane / 2 h / 20 °C
View Scheme
(Z)-2-Formyl-1-<(4-methoxyphenyl)methylene>-1,2,3,4,5,6,7,8-octahydroisoquinoline
116172-20-4

(Z)-2-Formyl-1-<(4-methoxyphenyl)methylene>-1,2,3,4,5,6,7,8-octahydroisoquinoline

dextromethorphan
125-71-3

dextromethorphan

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: H2 / Ru(OCOCF3)2<(S)-tolbinap> / methanol / 100 h / 30 °C / 76000.1 Torr
View Scheme
(S)-2-Formyl-1-<(4-methoxyphenyl)methyl>-1,2,3,4,5,6,7,8-octahydroispquinoline
29144-31-8

(S)-2-Formyl-1-<(4-methoxyphenyl)methyl>-1,2,3,4,5,6,7,8-octahydroispquinoline

dextromethorphan
125-71-3

dextromethorphan

2-(1-cyclohexenyl)ethylamine
3399-73-3

2-(1-cyclohexenyl)ethylamine

dextromethorphan
125-71-3

dextromethorphan

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 5 h / 150 °C
2: POCl3 / benzene / Heating
3: pyridine; tetrahydrofuran / 8 h / 0 °C
4: H2 / Ru(OCOCF3)2<(S)-tolbinap> / methanol / 100 h / 30 °C / 76000.1 Torr
View Scheme
Multi-step reaction with 5 steps
1.1: diisopropyl-carbodiimide; dmap / dichloromethane / 10 h / 0 - 20 °C
2.1: trichlorophosphate / toluene / 4 h / Reflux
3.1: phenylsilane; pyrrolidine / tetrahydrofuran; methanol / 5 h / 20 °C / Inert atmosphere
4.1: methanol / 0.25 h
4.2: 10 h / 20 °C
5.1: aluminum (III) chloride / dichloromethane / 2 h / 20 °C
View Scheme
Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: toluene; methanol
2: Gewinnung mit Hilfe von Lg-Weinsaeure
View Scheme
Multi-step reaction with 2 steps
1: methanol; toluene
2: Gewinnung mit Hilfe von Lg-Weinsaeure
View Scheme
tri(4-tolyl)aminium hexafluorophosphate

tri(4-tolyl)aminium hexafluorophosphate

phenylmagnesium bromide
100-58-3

phenylmagnesium bromide

dextromethorphan
125-71-3

dextromethorphan

A

tri(p-tolyl)amine
1159-53-1

tri(p-tolyl)amine

B

11-benzyl-3-methoxy-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene

11-benzyl-3-methoxy-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene

Conditions
ConditionsYield
Stage #1: tri(4-tolyl)aminium hexafluorophosphate; dextromethorphan With 1,4-diaza-bicyclo[2.2.2]octane In acetonitrile at -5℃; for 0.0833333h; Inert atmosphere;
Stage #2: phenylmagnesium bromide In tetrahydrofuran; acetonitrile at 0℃; for 0.0833333h; Inert atmosphere; regioselective reaction;
A 99%
B 83%
Conditions
ConditionsYield
Stage #1: dextromethorphan With 3-chloro-benzenecarboperoxoic acid Polonovski type reaction; Inert atmosphere;
Stage #2: With iron In chloroform at 20℃; Polonovski type reaction; Inert atmosphere;
97%
With BM3 variant 4H5 Enzymatic reaction;50%
With human CYP3A4 expressed in Escherichia coli; NADPH-regenerating system In phosphate buffer for 0.25h; pH=7.4; Enzyme kinetics; Further Variations:; Reagents;
dextromethorphan
125-71-3

dextromethorphan

2,2,2-Trichloroethyl chloroformate
17341-93-4

2,2,2-Trichloroethyl chloroformate

1,3,4,9,10,10A-hexahydro-6-methoxy-2H-10,4A-(iminoethano)phenanthrene-11-carboxylic acid
245407-53-8

1,3,4,9,10,10A-hexahydro-6-methoxy-2H-10,4A-(iminoethano)phenanthrene-11-carboxylic acid

Conditions
ConditionsYield
In toluene Heating;95%
In toluene for 2h; Heating;91.2%
dextromethorphan
125-71-3

dextromethorphan

methyl iodide
74-88-4

methyl iodide

ent-3-methoxy-17,17-dimethyl-9,10-didehydro-9,17-seco-morphinane
112349-71-0

ent-3-methoxy-17,17-dimethyl-9,10-didehydro-9,17-seco-morphinane

Conditions
ConditionsYield
Stage #1: dextromethorphan; methyl iodide
Stage #2: Alkaline hydrolysis;
95%
dextromethorphan
125-71-3

dextromethorphan

dextromethorphan N-oxide
113951-05-6

dextromethorphan N-oxide

Conditions
ConditionsYield
With perfluoro-cis-2-n-butyl-3-n-propyloxaziridine; HCFC-225ca,cb In dichloromethane at -60℃; for 0.333333h;94%
With methanol; water; dihydrogen peroxide
With dihydrogen peroxide In methanol at 20℃; for 48h;
dextromethorphan
125-71-3

dextromethorphan

dextromethorphan N-oxide hydrochloride
113951-04-5

dextromethorphan N-oxide hydrochloride

Conditions
ConditionsYield
Stage #1: dextromethorphan With m-CPBA In chloroform at -30 - -20℃;
Stage #2: With sodium hydroxide In chloroform; water
Stage #3: With hydrogenchloride In chloroform; water
94%
Stage #1: dextromethorphan With dihydrogen peroxide In methanol; water at 0 - 20℃; for 18h;
Stage #2: With hydrogenchloride In water
94%
dextromethorphan
125-71-3

dextromethorphan

[2H]-Dextromethorphan 17-d3
524713-56-2

[2H]-Dextromethorphan 17-d3

Conditions
ConditionsYield
With deuterium In tetrahydrofuran for 36h; Glovebox; Inert atmosphere; regioselective reaction;92%
C24H30N2O5S

C24H30N2O5S

dextromethorphan
125-71-3

dextromethorphan

C42H55N3O6S

C42H55N3O6S

Conditions
ConditionsYield
With (4s,6s)-2,4,5,6-tetra(9H-carbazol-9-yl)isophthalonitrile; sodium acetate In N,N-dimethyl-formamide at 20℃; for 16h; Irradiation; Inert atmosphere; diastereoselective reaction;86%
dextromethorphan
125-71-3

dextromethorphan

(+)-3-Methoxymorphinan hydrochloride

(+)-3-Methoxymorphinan hydrochloride

Conditions
ConditionsYield
Stage #1: dextromethorphan With carbonochloridic acid 1-chloro-ethyl ester In toluene at 20℃; for 1h;
Stage #2: With methanol In toluene at 65℃; for 1h; Reflux;
84.1%
1,4-diaza-bicyclo[2.2.2]octane
280-57-9

1,4-diaza-bicyclo[2.2.2]octane

sodium hydrogencarbonate
144-55-8

sodium hydrogencarbonate

dextromethorphan
125-71-3

dextromethorphan

A

1-(3-methoxy-11-methyl-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoetheno)phenanthren-13-yl)-1,4-diazabicyclo[2.2.2]octan-1-ium bicarbonate

1-(3-methoxy-11-methyl-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoetheno)phenanthren-13-yl)-1,4-diazabicyclo[2.2.2]octan-1-ium bicarbonate

Conditions
ConditionsYield
Stage #1: 1,4-diaza-bicyclo[2.2.2]octane; dextromethorphan With tri(4-tolyl)aminium hexafluorophosphate In acetonitrile at -5℃; for 0.0833333h; Inert atmosphere;
Stage #2: sodium hydrogencarbonate With water chemoselective reaction;
A 8%
B 83%
ethylmagnesium bromide
925-90-6

ethylmagnesium bromide

dextromethorphan
125-71-3

dextromethorphan

3-methoxy-11-propyl-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene

3-methoxy-11-propyl-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene

Conditions
ConditionsYield
Stage #1: dextromethorphan With 1,4-diaza-bicyclo[2.2.2]octane; tri(4-tolyl)aminium hexafluorophosphate In acetonitrile at -5℃; for 0.0833333h; Inert atmosphere;
Stage #2: ethylmagnesium bromide In diethyl ether; acetonitrile at 0℃; for 0.0833333h; Inert atmosphere; regioselective reaction;
81%
dextromethorphan
125-71-3

dextromethorphan

(+)-dextrorphan
125-73-5

(+)-dextrorphan

Conditions
ConditionsYield
With SoLo unspecific peroxygenase In aq. phosphate buffer; acetonitrile at 30℃; for 16.5h; pH=7; Reagent/catalyst; Enzymatic reaction;75.2%
With cytochrome P450 2D6 expressed in human lymphoblast cells In phosphate buffer at 37℃; pH=7.4; Enzyme kinetics;
With yeast expressing CYP2D6 microsomes In phosphate buffer at 37℃; for 0.25h; pH=7.4; Enzyme kinetics; Further Variations:; Reagents;
vinyl magnesium bromide
1826-67-1

vinyl magnesium bromide

dextromethorphan
125-71-3

dextromethorphan

11-allyl-3-methoxy-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene
131723-91-6

11-allyl-3-methoxy-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene

Conditions
ConditionsYield
Stage #1: dextromethorphan With 1,4-diaza-bicyclo[2.2.2]octane; tri(4-tolyl)aminium hexafluorophosphate In acetonitrile at -5℃; for 0.0833333h; Inert atmosphere;
Stage #2: vinyl magnesium bromide In tetrahydrofuran; acetonitrile at 0℃; for 0.0833333h; Inert atmosphere; regioselective reaction;
75%
(trimethylsilyl)methylmagnesium chloride
13170-43-9

(trimethylsilyl)methylmagnesium chloride

dextromethorphan
125-71-3

dextromethorphan

(4bS,8aS,9S)-11-methyl-3-((trimethylsilyl)methyl)-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene

(4bS,8aS,9S)-11-methyl-3-((trimethylsilyl)methyl)-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene

Conditions
ConditionsYield
With nickel diacetate; 1,3-dicyclohexyl-1H-imidazol-3-ium chloride In tetrahydrofuran; toluene at 80℃; for 18h; Inert atmosphere; Sealed tube;74%
cyclopropylmagnesium bromide
23719-80-4

cyclopropylmagnesium bromide

dextromethorphan
125-71-3

dextromethorphan

11-(cyclopropylmethyl)-3-methoxy-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene

11-(cyclopropylmethyl)-3-methoxy-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene

Conditions
ConditionsYield
Stage #1: dextromethorphan With 1,4-diaza-bicyclo[2.2.2]octane; tri(4-tolyl)aminium hexafluorophosphate In acetonitrile at -5℃; for 0.0833333h; Inert atmosphere;
Stage #2: cyclopropylmagnesium bromide In 2-methyltetrahydrofuran; acetonitrile at 0℃; for 0.0833333h; Inert atmosphere; regioselective reaction;
74%
phenylmagnesium bromide
1589-82-8

phenylmagnesium bromide

dextromethorphan
125-71-3

dextromethorphan

(4bS,8aS,9S)-3-benzyl-11-methyl-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene

(4bS,8aS,9S)-3-benzyl-11-methyl-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene

Conditions
ConditionsYield
With nickel diacetate; 1,3-dicyclohexyl-1H-imidazol-3-ium chloride In tetrahydrofuran; toluene at 100℃; for 18h; Inert atmosphere; Sealed tube;72%
allyl iodid
556-56-9

allyl iodid

dextromethorphan
125-71-3

dextromethorphan

11-(but-3-en-1-yl)-3-methoxy-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene

11-(but-3-en-1-yl)-3-methoxy-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene

Conditions
ConditionsYield
Stage #1: dextromethorphan With 1,4-diaza-bicyclo[2.2.2]octane; tri(4-tolyl)aminium hexafluorophosphate In acetonitrile at -5℃; for 0.0833333h; Inert atmosphere;
Stage #2: allyl iodid With indium In N,N-dimethyl-formamide; acetonitrile at 0℃; for 0.0833333h; Inert atmosphere; regioselective reaction;
71%
allyl bromide
106-95-6

allyl bromide

dextromethorphan
125-71-3

dextromethorphan

Allyl-[2-((4aS,10aR)-6-methoxy-1,3,4,10a-tetrahydro-2H-phenanthren-4a-yl)-ethyl]-methyl-amine

Allyl-[2-((4aS,10aR)-6-methoxy-1,3,4,10a-tetrahydro-2H-phenanthren-4a-yl)-ethyl]-methyl-amine

Conditions
ConditionsYield
Stage #1: allyl bromide; dextromethorphan
Stage #2: Alkaline hydrolysis;
67%
dextromethorphan
125-71-3

dextromethorphan

(+)-2-amino-3-methoxy-17-methyl-9α,13α,14α-morphinan

(+)-2-amino-3-methoxy-17-methyl-9α,13α,14α-morphinan

Conditions
ConditionsYield
Stage #1: dextromethorphan With sulfuric acid; hydroxylamine hydrochloride In acetonitrile at 25℃; for 0.166667h;
Stage #2: With hydrogenchloride; titanium(III) chloride In water; acetonitrile at 25℃; Inert atmosphere; Sealed tube;
65%
benzyl (2S,4S)-2-(tert-butyl)-4-isobutyl-5-oxooxazolidine-3-carboxylate
163084-89-7

benzyl (2S,4S)-2-(tert-butyl)-4-isobutyl-5-oxooxazolidine-3-carboxylate

dextromethorphan
125-71-3

dextromethorphan

C34H44N2O5

C34H44N2O5

Conditions
ConditionsYield
With [4,4’-bis(1,1-dimethylethyl)-2,2’-bipyridine-N1,N1‘]bis [3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-N]phenyl-C]iridium(III) hexafluorophosphate In acetonitrile at 23℃; for 12h; Irradiation; chemoselective reaction;64%
neopentylmagnesium bromide
33974-41-3

neopentylmagnesium bromide

dextromethorphan
125-71-3

dextromethorphan

(4bS,8aS,9S)-11-methyl-3-neopentyl-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene

(4bS,8aS,9S)-11-methyl-3-neopentyl-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene

Conditions
ConditionsYield
With nickel diacetate; 1,3-dicyclohexyl-1H-imidazol-3-ium chloride In tetrahydrofuran; toluene at 100℃; for 18h; Inert atmosphere; Sealed tube;60%
2-Bromoethyl methyl ether
6482-24-2

2-Bromoethyl methyl ether

dextromethorphan
125-71-3

dextromethorphan

(2-Methoxy-ethyl)-[2-((4aS,10aR)-6-methoxy-1,3,4,10a-tetrahydro-2H-phenanthren-4a-yl)-ethyl]-methyl-amine

(2-Methoxy-ethyl)-[2-((4aS,10aR)-6-methoxy-1,3,4,10a-tetrahydro-2H-phenanthren-4a-yl)-ethyl]-methyl-amine

Conditions
ConditionsYield
Stage #1: 2-Bromoethyl methyl ether; dextromethorphan
Stage #2: Alkaline hydrolysis;
59%
dextromethorphan
125-71-3

dextromethorphan

C18H27NO

C18H27NO

Conditions
ConditionsYield
With N,N'-Dimethylurea; tris(pyrrolidino)phosphine oxide; lithium bromide In tetrahydrofuran at 20℃; Electrochemical reaction;59%
4-penten-1-ylmagnesium bromide
34164-50-6

4-penten-1-ylmagnesium bromide

dextromethorphan
125-71-3

dextromethorphan

11-(hex-5-en-1-yl)-3-methoxy-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene

11-(hex-5-en-1-yl)-3-methoxy-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene

Conditions
ConditionsYield
Stage #1: dextromethorphan With 1,4-diaza-bicyclo[2.2.2]octane; tri(4-tolyl)aminium hexafluorophosphate In acetonitrile at -5℃; for 0.0833333h; Inert atmosphere;
Stage #2: 4-penten-1-ylmagnesium bromide In tetrahydrofuran; acetonitrile at 0℃; for 0.0833333h; Inert atmosphere; regioselective reaction;
57%
tris-iso-propylsilyl acetylene
89343-06-6

tris-iso-propylsilyl acetylene

dextromethorphan
125-71-3

dextromethorphan

(4bS,8aS,9S)-11-methyl-3-((triisopropylsilyl)ethynyl)-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene

(4bS,8aS,9S)-11-methyl-3-((triisopropylsilyl)ethynyl)-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene

Conditions
ConditionsYield
Stage #1: tris-iso-propylsilyl acetylene With ethylmagnesium bromide In tetrahydrofuran at 20℃; for 0.0833333h; Inert atmosphere; Glovebox;
Stage #2: dextromethorphan With bis(1,5-cyclooctadiene)nickel (0); 1,3-dicyclohexyl-1H-imidazol-3-ium chloride In 1,4-dioxane at 120℃; for 18h; Inert atmosphere; Sealed tube;
52%
4-but-1-enylmagnesium bromide
7103-09-5

4-but-1-enylmagnesium bromide

dextromethorphan
125-71-3

dextromethorphan

3-methoxy-11-(pent-4-en-1-yl)-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene

3-methoxy-11-(pent-4-en-1-yl)-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene

Conditions
ConditionsYield
Stage #1: dextromethorphan With 1,4-diaza-bicyclo[2.2.2]octane; tri(4-tolyl)aminium hexafluorophosphate In acetonitrile at -5℃; for 0.0833333h; Inert atmosphere;
Stage #2: 4-but-1-enylmagnesium bromide In tetrahydrofuran; acetonitrile at 0℃; for 0.0833333h; Inert atmosphere; regioselective reaction;
48%

Downstream Products

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View