Xi’an Quanao Biotech Co., Ltd. with 18 years experience in plant extract filed. Product grade: Medicine, Health care product, Cosmetics, Food, Beverage, Feed. Hot selling market: Europe, North America, South America, Middle East, Asia Pacifi
Cas:125-71-3
Min.Order:1 Kilogram
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inquiryDextromethorphan [NO. 125-71-3] CAS [product name] Chinese dextromethorphan [product name] Dextromethorphan [product] effect of dextromethorphan as antitussive, [indications] cough caused by upper respiratory tract infection
Cas:125-71-3
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inquiryShanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu
Cas:125-71-3
Min.Order:1 Kilogram
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inquiryName:dextromethorphan CAS NO:125-71-3 Grade:For chemical industry, scientific research and export Product Quality 12 years of chemical raw materials Mature operation of the industry System stability Data storage Security without vulnerability
Cas:125-71-3
Min.Order:25 Kilogram
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inquiryAdvantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&
Cas:125-71-3
Min.Order:1 Gram
FOB Price: $0.9 / 1.0
Type:Lab/Research institutions
inquiryOur advantages: 1. High quality and competitive price: 1) Standard: BP/USP/EP/ enterprise standard 2) All purity 鈮 9% 3) We are manufacturers and can provide high quality products at factory prices. 2. Fast and safe delivery 1) The package can
Cas:125-71-3
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inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:125-71-3
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by email in time prod
Cas:125-71-3
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryAdvantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best s
Dextromethorphan CAS:125-71-3 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermedi
Cas:125-71-3
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryDEXTROMETHORPHAN CAS: 125-71-3 Specification Boiling point 414.48°C (rough estimate) density 1.0115 (rough estimate) refractive index 1.5740 (estimate) Fp 9℃ storage temp. 20°
Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Cas:125-71-3
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryOur Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter
Cas:125-71-3
Min.Order:1 Kilogram
FOB Price: $1.0 / 100000.0
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inquirySuperior quality, moderate price & quick delivery. Appearance:white crystalline powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:as per your request Application:Respiratory System Agents Transportati
Dextromethorphan CAS 125-71-3 Purity: 99% Min Application: Intermediates Appearance: Powder Package: Bag Delivery: 3-5days Our Advantage & Service 1.Top quality: Using high quality material and establishing a strict quality control s
Cas:125-71-3
Min.Order:1 Kilogram
FOB Price: $10.0 / 50.0
Type:Trading Company
inquiryOur Advantage & Service 1.Top quality: Using high quality material and establishing a strict quality control system,assigning specific persons in charge of each part of production,from raw material purchase to assembly. 2 Professional R&D
Cas:125-71-3
Min.Order:10 Gram
FOB Price: $5.0 / 7.0
Type:Trading Company
inquiry1.high purity 2.consistent quality 3.competitive price 4.fast shipping Binbo Biological Products Co. Ltd., is a professional high-tech enterprise which engaged in Biological products and raw materials. Binbo is engaged in R&D with perfect eq
Cas:125-71-3
Min.Order:1 Kilogram
FOB Price: $10.0 / 100.0
Type:Lab/Research institutions
inquiryEstablished in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site
The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providing h
Our company was built in 2009 with an ISO certificate. In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so o
Cas:125-71-3
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryProduct name: N-Methyl-3-Methoxy-Morphinan CAS No.: 125-71-3 Molecule Formula:C18H25NO Molecule Weight:271.40 Purity: 99.0% Package: 25kg/drum Description:White powder Manufacture Standards:Enterprise Standard TESTING ITEMS
Cas:125-71-3
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryGMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,
Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed
Cas:125-71-3
Min.Order:1 Kilogram
FOB Price: $2.0
Type:Lab/Research institutions
inquiryShandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W
Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service an
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Cas:125-71-3
Min.Order:1 Gram
FOB Price: $1.0
Type:Trading Company
inquiryWhy is SINOWAY:1) Specialized in pharmaceutical and healthcare industrial since 19872) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days.4) We have warehouse in USA with quickly shipment . Application:API
Cas:125-71-3
Min.Order:0
Negotiable
Type:Trading Company
inquiryTAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp
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dextromethorphan
Conditions | Yield |
---|---|
With sodium hydroxide In water pH=10; Inert atmosphere; | 100% |
With ammonia In chloroform; water at 20℃; for 1h; | |
With ammonia In methanol at 20℃; for 1h; | |
With sodium hydroxide In water | |
In chloroform at 20℃; for 1h; | 2.88 g |
Conditions | Yield |
---|---|
With sodium hydroxide In chloroform; water for 0.5h; | 97.98% |
dextromethorphan N-oxide hydrochloride
A
(+)-3-methoxymorphinan
B
dextromethorphan
Conditions | Yield |
---|---|
Stage #1: dextromethorphan N-oxide hydrochloride With ferrocene In chloroform at 40℃; for 72h; Stage #2: With sodium hydroxide In chloroform; water | A 92% B 8% |
With ferrocene In chloroform at 40℃; for 40h; Polonovski reaction; Inert atmosphere; | A 92% B 8% |
(+)-2-methyl-1-(4-methoxy)benzyl-1,2,3,4,5,6,7,8-hexahydroisoquinoline
dextromethorphan
Conditions | Yield |
---|---|
With aluminum (III) chloride In dichloromethane at 20℃; for 2h; Reagent/catalyst; | 91% |
rac-3-methoxy-17-methyl-morphinane
dextromethorphan
Conditions | Yield |
---|---|
Gewinnung mit Hilfe von Lg-Weinsaeure; | |
Gewinnung mit Hilfe von Lg-Weinsaeure; |
(9α,13α,14α)-3-methoxy-17-methylmorphinan-10-one
A
dextromethorphan
B
ent-3-methoxy-17-methyl-morphinan-10β-ol
Conditions | Yield |
---|---|
With lithium aluminium tetrahydride; diethyl ether |
(+)-3-methoxy-N-formylmorphinan
dextromethorphan
Conditions | Yield |
---|---|
With methanol; toluene | |
With methanol; toluene |
Conditions | Yield |
---|---|
Multi-step reaction with 6 steps 1: 5 h / 150 °C 2: POCl3 / benzene / Heating 3: pyridine; tetrahydrofuran / 8 h / 0 °C 4: H2 / Ru(OCOCF3)2<(S)-tolbinap> / methanol / 100 h / 30 °C / 76000.1 Torr View Scheme | |
Multi-step reaction with 5 steps 1.1: diisopropyl-carbodiimide; dmap / dichloromethane / 10 h / 0 - 20 °C 2.1: trichlorophosphate / toluene / 4 h / Reflux 3.1: phenylsilane; pyrrolidine / tetrahydrofuran; methanol / 5 h / 20 °C / Inert atmosphere 4.1: methanol / 0.25 h 4.2: 10 h / 20 °C 5.1: aluminum (III) chloride / dichloromethane / 2 h / 20 °C View Scheme |
1-(4-methoxybenzyl)-3,4,5,6,7,8-hexahydro-isoquinoline
dextromethorphan
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: pyridine; tetrahydrofuran / 8 h / 0 °C 2: H2 / Ru(OCOCF3)2<(S)-tolbinap> / methanol / 100 h / 30 °C / 76000.1 Torr View Scheme | |
Multi-step reaction with 3 steps 1.1: phenylsilane; pyrrolidine / tetrahydrofuran; methanol / 5 h / 20 °C / Inert atmosphere 2.1: methanol / 0.25 h 2.2: 10 h / 20 °C 3.1: aluminum (III) chloride / dichloromethane / 2 h / 20 °C View Scheme |
N-(2-cyclohex-1-enylethyl)-2-(4-methoxyphenyl)-acetamide
dextromethorphan
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: POCl3 / benzene / Heating 2: pyridine; tetrahydrofuran / 8 h / 0 °C 3: H2 / Ru(OCOCF3)2<(S)-tolbinap> / methanol / 100 h / 30 °C / 76000.1 Torr View Scheme | |
Multi-step reaction with 4 steps 1.1: trichlorophosphate / toluene / 4 h / Reflux 2.1: phenylsilane; pyrrolidine / tetrahydrofuran; methanol / 5 h / 20 °C / Inert atmosphere 3.1: methanol / 0.25 h 3.2: 10 h / 20 °C 4.1: aluminum (III) chloride / dichloromethane / 2 h / 20 °C View Scheme |
(Z)-2-Formyl-1-<(4-methoxyphenyl)methylene>-1,2,3,4,5,6,7,8-octahydroisoquinoline
dextromethorphan
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: H2 / Ru(OCOCF3)2<(S)-tolbinap> / methanol / 100 h / 30 °C / 76000.1 Torr View Scheme |
(S)-2-Formyl-1-<(4-methoxyphenyl)methyl>-1,2,3,4,5,6,7,8-octahydroispquinoline
dextromethorphan
Conditions | Yield |
---|---|
Multi-step reaction with 6 steps 1: 5 h / 150 °C 2: POCl3 / benzene / Heating 3: pyridine; tetrahydrofuran / 8 h / 0 °C 4: H2 / Ru(OCOCF3)2<(S)-tolbinap> / methanol / 100 h / 30 °C / 76000.1 Torr View Scheme | |
Multi-step reaction with 5 steps 1.1: diisopropyl-carbodiimide; dmap / dichloromethane / 10 h / 0 - 20 °C 2.1: trichlorophosphate / toluene / 4 h / Reflux 3.1: phenylsilane; pyrrolidine / tetrahydrofuran; methanol / 5 h / 20 °C / Inert atmosphere 4.1: methanol / 0.25 h 4.2: 10 h / 20 °C 5.1: aluminum (III) chloride / dichloromethane / 2 h / 20 °C View Scheme |
dextromethorphan
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: toluene; methanol 2: Gewinnung mit Hilfe von Lg-Weinsaeure View Scheme | |
Multi-step reaction with 2 steps 1: methanol; toluene 2: Gewinnung mit Hilfe von Lg-Weinsaeure View Scheme |
Conditions | Yield |
---|---|
Stage #1: tri(4-tolyl)aminium hexafluorophosphate; dextromethorphan With 1,4-diaza-bicyclo[2.2.2]octane In acetonitrile at -5℃; for 0.0833333h; Inert atmosphere; Stage #2: phenylmagnesium bromide In tetrahydrofuran; acetonitrile at 0℃; for 0.0833333h; Inert atmosphere; regioselective reaction; | A 99% B 83% |
dextromethorphan
(+)-3-methoxymorphinan
Conditions | Yield |
---|---|
Stage #1: dextromethorphan With 3-chloro-benzenecarboperoxoic acid Polonovski type reaction; Inert atmosphere; Stage #2: With iron In chloroform at 20℃; Polonovski type reaction; Inert atmosphere; | 97% |
With BM3 variant 4H5 Enzymatic reaction; | 50% |
With human CYP3A4 expressed in Escherichia coli; NADPH-regenerating system In phosphate buffer for 0.25h; pH=7.4; Enzyme kinetics; Further Variations:; Reagents; |
dextromethorphan
2,2,2-Trichloroethyl chloroformate
1,3,4,9,10,10A-hexahydro-6-methoxy-2H-10,4A-(iminoethano)phenanthrene-11-carboxylic acid
Conditions | Yield |
---|---|
In toluene Heating; | 95% |
In toluene for 2h; Heating; | 91.2% |
dextromethorphan
methyl iodide
ent-3-methoxy-17,17-dimethyl-9,10-didehydro-9,17-seco-morphinane
Conditions | Yield |
---|---|
Stage #1: dextromethorphan; methyl iodide Stage #2: Alkaline hydrolysis; | 95% |
dextromethorphan
dextromethorphan N-oxide
Conditions | Yield |
---|---|
With perfluoro-cis-2-n-butyl-3-n-propyloxaziridine; HCFC-225ca,cb In dichloromethane at -60℃; for 0.333333h; | 94% |
With methanol; water; dihydrogen peroxide | |
With dihydrogen peroxide In methanol at 20℃; for 48h; |
dextromethorphan
dextromethorphan N-oxide hydrochloride
Conditions | Yield |
---|---|
Stage #1: dextromethorphan With m-CPBA In chloroform at -30 - -20℃; Stage #2: With sodium hydroxide In chloroform; water Stage #3: With hydrogenchloride In chloroform; water | 94% |
Stage #1: dextromethorphan With dihydrogen peroxide In methanol; water at 0 - 20℃; for 18h; Stage #2: With hydrogenchloride In water | 94% |
dextromethorphan
[2H]-Dextromethorphan 17-d3
Conditions | Yield |
---|---|
With deuterium In tetrahydrofuran for 36h; Glovebox; Inert atmosphere; regioselective reaction; | 92% |
Conditions | Yield |
---|---|
With (4s,6s)-2,4,5,6-tetra(9H-carbazol-9-yl)isophthalonitrile; sodium acetate In N,N-dimethyl-formamide at 20℃; for 16h; Irradiation; Inert atmosphere; diastereoselective reaction; | 86% |
dextromethorphan
Conditions | Yield |
---|---|
Stage #1: dextromethorphan With carbonochloridic acid 1-chloro-ethyl ester In toluene at 20℃; for 1h; Stage #2: With methanol In toluene at 65℃; for 1h; Reflux; | 84.1% |
1,4-diaza-bicyclo[2.2.2]octane
sodium hydrogencarbonate
dextromethorphan
B
(+)-3-methoxymorphinan
Conditions | Yield |
---|---|
Stage #1: 1,4-diaza-bicyclo[2.2.2]octane; dextromethorphan With tri(4-tolyl)aminium hexafluorophosphate In acetonitrile at -5℃; for 0.0833333h; Inert atmosphere; Stage #2: sodium hydrogencarbonate With water chemoselective reaction; | A 8% B 83% |
Conditions | Yield |
---|---|
Stage #1: dextromethorphan With 1,4-diaza-bicyclo[2.2.2]octane; tri(4-tolyl)aminium hexafluorophosphate In acetonitrile at -5℃; for 0.0833333h; Inert atmosphere; Stage #2: ethylmagnesium bromide In diethyl ether; acetonitrile at 0℃; for 0.0833333h; Inert atmosphere; regioselective reaction; | 81% |
Conditions | Yield |
---|---|
With SoLo unspecific peroxygenase In aq. phosphate buffer; acetonitrile at 30℃; for 16.5h; pH=7; Reagent/catalyst; Enzymatic reaction; | 75.2% |
With cytochrome P450 2D6 expressed in human lymphoblast cells In phosphate buffer at 37℃; pH=7.4; Enzyme kinetics; | |
With yeast expressing CYP2D6 microsomes In phosphate buffer at 37℃; for 0.25h; pH=7.4; Enzyme kinetics; Further Variations:; Reagents; |
vinyl magnesium bromide
dextromethorphan
11-allyl-3-methoxy-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene
Conditions | Yield |
---|---|
Stage #1: dextromethorphan With 1,4-diaza-bicyclo[2.2.2]octane; tri(4-tolyl)aminium hexafluorophosphate In acetonitrile at -5℃; for 0.0833333h; Inert atmosphere; Stage #2: vinyl magnesium bromide In tetrahydrofuran; acetonitrile at 0℃; for 0.0833333h; Inert atmosphere; regioselective reaction; | 75% |
(trimethylsilyl)methylmagnesium chloride
dextromethorphan
Conditions | Yield |
---|---|
With nickel diacetate; 1,3-dicyclohexyl-1H-imidazol-3-ium chloride In tetrahydrofuran; toluene at 80℃; for 18h; Inert atmosphere; Sealed tube; | 74% |
cyclopropylmagnesium bromide
dextromethorphan
Conditions | Yield |
---|---|
Stage #1: dextromethorphan With 1,4-diaza-bicyclo[2.2.2]octane; tri(4-tolyl)aminium hexafluorophosphate In acetonitrile at -5℃; for 0.0833333h; Inert atmosphere; Stage #2: cyclopropylmagnesium bromide In 2-methyltetrahydrofuran; acetonitrile at 0℃; for 0.0833333h; Inert atmosphere; regioselective reaction; | 74% |
Conditions | Yield |
---|---|
With nickel diacetate; 1,3-dicyclohexyl-1H-imidazol-3-ium chloride In tetrahydrofuran; toluene at 100℃; for 18h; Inert atmosphere; Sealed tube; | 72% |
Conditions | Yield |
---|---|
Stage #1: dextromethorphan With 1,4-diaza-bicyclo[2.2.2]octane; tri(4-tolyl)aminium hexafluorophosphate In acetonitrile at -5℃; for 0.0833333h; Inert atmosphere; Stage #2: allyl iodid With indium In N,N-dimethyl-formamide; acetonitrile at 0℃; for 0.0833333h; Inert atmosphere; regioselective reaction; | 71% |
Conditions | Yield |
---|---|
Stage #1: allyl bromide; dextromethorphan Stage #2: Alkaline hydrolysis; | 67% |
dextromethorphan
Conditions | Yield |
---|---|
Stage #1: dextromethorphan With sulfuric acid; hydroxylamine hydrochloride In acetonitrile at 25℃; for 0.166667h; Stage #2: With hydrogenchloride; titanium(III) chloride In water; acetonitrile at 25℃; Inert atmosphere; Sealed tube; | 65% |
benzyl (2S,4S)-2-(tert-butyl)-4-isobutyl-5-oxooxazolidine-3-carboxylate
dextromethorphan
Conditions | Yield |
---|---|
With [4,4’-bis(1,1-dimethylethyl)-2,2’-bipyridine-N1,N1‘]bis [3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-N]phenyl-C]iridium(III) hexafluorophosphate In acetonitrile at 23℃; for 12h; Irradiation; chemoselective reaction; | 64% |
neopentylmagnesium bromide
dextromethorphan
Conditions | Yield |
---|---|
With nickel diacetate; 1,3-dicyclohexyl-1H-imidazol-3-ium chloride In tetrahydrofuran; toluene at 100℃; for 18h; Inert atmosphere; Sealed tube; | 60% |
Conditions | Yield |
---|---|
Stage #1: 2-Bromoethyl methyl ether; dextromethorphan Stage #2: Alkaline hydrolysis; | 59% |
dextromethorphan
Conditions | Yield |
---|---|
With N,N'-Dimethylurea; tris(pyrrolidino)phosphine oxide; lithium bromide In tetrahydrofuran at 20℃; Electrochemical reaction; | 59% |
4-penten-1-ylmagnesium bromide
dextromethorphan
Conditions | Yield |
---|---|
Stage #1: dextromethorphan With 1,4-diaza-bicyclo[2.2.2]octane; tri(4-tolyl)aminium hexafluorophosphate In acetonitrile at -5℃; for 0.0833333h; Inert atmosphere; Stage #2: 4-penten-1-ylmagnesium bromide In tetrahydrofuran; acetonitrile at 0℃; for 0.0833333h; Inert atmosphere; regioselective reaction; | 57% |
tris-iso-propylsilyl acetylene
dextromethorphan
Conditions | Yield |
---|---|
Stage #1: tris-iso-propylsilyl acetylene With ethylmagnesium bromide In tetrahydrofuran at 20℃; for 0.0833333h; Inert atmosphere; Glovebox; Stage #2: dextromethorphan With bis(1,5-cyclooctadiene)nickel (0); 1,3-dicyclohexyl-1H-imidazol-3-ium chloride In 1,4-dioxane at 120℃; for 18h; Inert atmosphere; Sealed tube; | 52% |
Conditions | Yield |
---|---|
Stage #1: dextromethorphan With 1,4-diaza-bicyclo[2.2.2]octane; tri(4-tolyl)aminium hexafluorophosphate In acetonitrile at -5℃; for 0.0833333h; Inert atmosphere; Stage #2: 4-but-1-enylmagnesium bromide In tetrahydrofuran; acetonitrile at 0℃; for 0.0833333h; Inert atmosphere; regioselective reaction; | 48% |
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