1-Propanol,2-(dimethylamino)- supplier

Name
DL-2-DIMETHYLAMINO-1-PROPANOL
EINECS 239-558-7
CAS No. 15521-18-3
Article Data10
CAS DataBase
Density 0.887 g/cm³
Solubility
Melting Point 29.84°C (estimate)
Formula C₅H₁₃NO
Boiling Point 133.8 °C at 760 mmHg
Molecular Weight 103.164
Flash Point 32.1 °C
Transport Information
Appearance
Safety
Risk Codes
Molecular Structure
Hazard Symbols Xi
Synonyms 2-(Dimethylamino)-1-propanol;2-(Dimethylamino)propanol;N,N-Dimethyl-2-aminopropan-1-ol;NSC 17707;NSC 26882;
PSA 23.47000
LogP -0.07120

Synthetic route

: 50-00-0
formaldehyd

: 6168-72-5
2-Amino-1-propanol

: 15521-18-3
2-(dimethylamino)propan-1-ol

Conditions

Conditions	Yield
With formic acid
With ethanol; water; sodium acetate Hydrieren des Reaktionsgemisches in Gegenwart von Raney-Nickel bei 65grad/70 at;
With formic acid

: 108-14-5
2-chloro-1-dimethylaminopropane

: 15521-18-3
2-(dimethylamino)propan-1-ol

Conditions

Conditions	Yield
With silver(l) oxide

: 82614-49-1
ethyl 2-(N,N-dimethylamino)-propionate

: 15521-18-3
2-(dimethylamino)propan-1-ol

Conditions

Conditions	Yield
With lithium aluminium tetrahydride In diethyl ether

: 124-40-3
dimethyl amine

: 598-72-1
2-Bromopropionic acid

: 15521-18-3
2-(dimethylamino)propan-1-ol

Conditions

Conditions	Yield
(i) H2O, (ii) EtOH, HCl, (iii) LiAlH4, Et2O; Multistep reaction;

: 124-40-3
dimethyl amine

: 535-11-5, 41978-69-2
Ethyl 2-bromopropionate

: 15521-18-3
2-(dimethylamino)propan-1-ol

Conditions

Conditions	Yield
(i) Et2O, (ii) LiAlH4; Multistep reaction;

: C59H104N2O15

A: 15521-18-3
2-(dimethylamino)propan-1-ol

B: 2-dimethylamino-3-methoxypropanol

C: (2E,4E,14E,20E)-(23S,24R,25S,26S,29R,30S,31R,32R)-13,19,34,34-Tetramethoxy-8,10,14,17,24,26,30,32-octamethyl-tetratriaconta-2,4,14,20-tetraene-1,7,9,23,25,29,31-heptaol

Conditions

Conditions	Yield
With lithium aluminium tetrahydride In diethyl ether at 23℃;

...Expand

α-dimethylamino-propionic acid ethyl ester: α-dimethylamino-propionic acid ethyl ester

: 15521-18-3
2-(dimethylamino)propan-1-ol

Conditions

Conditions	Yield
With ethanol; sodium

: 108-14-5
2-chloro-1-dimethylaminopropane

moist silver oxide: moist silver oxide

: 15521-18-3
2-(dimethylamino)propan-1-ol

: 540-72-7
sodium thiocyanide

: 6046-93-1
copper(II) acetate monohydrate

: 15521-18-3
2-(dimethylamino)propan-1-ol

: 59451-06-8, 500314-74-9
[Cu((CH3)3NCHCH2O)(NCS)]2

Conditions

Conditions	Yield
In methanol MeOH soln. of NaNCS was added to MeOH soln. of Cu(OAc)2*H2O and ligand, allowed to stand at 25°C for several ds; filtered, dried in vacuo; elem. anal.;	90%

...Expand

: 311334-77-7
5-(2-Chloro-phenyl)-2-methylsulfonyl-pyrimidine-4-carboxylic acid (3,5-bis-trifluoromethyl-benzyl)-methyl-amide

: 15521-18-3
2-(dimethylamino)propan-1-ol

: 311334-83-5
5-(2-chloro-phenyl)-2-(3-dimethylamino-propoxy)-pyrimidine-4-carboxylic acid (3,5-bis-trifluoromethyl-benzyl)-methyl-amide

Conditions

Conditions	Yield
With caesium carbonate In acetonitrile for 16h;	77%

: 15521-18-3
2-(dimethylamino)propan-1-ol

: 127-19-5
N,N-dimethyl acetamide

Conditions

Conditions	Yield
With potassium hydroxide; air In diethyl ether at 20℃; for 90h;	73%

: 1871-76-7
diphenylacetic acid chloride

: 15521-18-3
2-(dimethylamino)propan-1-ol

: diphenyl-acetic acid-(2-dimethylamino-propyl ester)

Conditions

Conditions	Yield
With benzene

: 37089-77-3
3,3-diphenylpropanoyl chloride

: 15521-18-3
2-(dimethylamino)propan-1-ol

: 3,3-diphenyl-propionic acid-(2-dimethylamino-propyl ester)

: 6292-88-2
N,N-dicyclohexylcarbamoyl chloride

: 15521-18-3
2-(dimethylamino)propan-1-ol

: dicyclohexyl-carbamic acid-(2-dimethylamino-propyl ester)

Conditions

Conditions	Yield
With toluene

: 15521-18-3
2-(dimethylamino)propan-1-ol

: 108-24-7
acetic anhydride

: 26290-68-6
(β-acetoxy-isopropyl)-trimethyl-ammonium; iodide

Conditions

Conditions	Yield
Umsetzung des Reaktionsprodukts mit Methyljodid;

: 15521-18-3
2-(dimethylamino)propan-1-ol

: 543-20-4
succinoyl dichloride

: 96434-49-0
succinic acid bis-(2-dimethylamino-propyl ester)

Conditions

Conditions	Yield
With hydrogenchloride; chloroform

: 15521-18-3
2-(dimethylamino)propan-1-ol

: 814-68-6
acryloyl chloride

: 99969-68-3
acrylic acid-(2-dimethylamino-propyl ester)

Conditions

Conditions	Yield
With benzene

: 15521-18-3
2-(dimethylamino)propan-1-ol

: 74-88-4
methyl iodide

: 3645-02-1
(β-hydroxy-isopropyl)-trimethyl-ammonium; hydroxide

Conditions

Conditions	Yield
With ethanol und nachfolgendem Behandeln des entstandenen Jodids mit Silberoxyd;

: 15521-18-3
2-(dimethylamino)propan-1-ol

: 74-88-4
methyl iodide

: 4188-22-1
(β-hydroxy-isopropyl)-trimethyl-ammonium; iodide

Conditions

Conditions	Yield
With ethanol

: 15521-18-3
2-(dimethylamino)propan-1-ol

: 17256-39-2
2-(dimethyl-amino)-1-methylethylchloride hydrochloride

Conditions

Conditions	Yield
With thionyl chloride; chloroform
With thionyl chloride; benzene zuletzt bei Siedepemperatur;
With thionyl chloride In chloroform at -60 - 60℃;

: 15521-18-3
2-(dimethylamino)propan-1-ol

: 108-14-5
2-chloro-1-dimethylaminopropane

Conditions

Conditions	Yield
With thionyl chloride; benzene

: 96-09-3
styrene oxide

: 15521-18-3
2-(dimethylamino)propan-1-ol

: 93309-65-0
2-(2-Dimethylamino-propyloxy)-1-phenyl-ethanol-(1)

Conditions

Conditions	Yield
(i) Na, (ii) /BRN= 108582/; Multistep reaction;

: 76-89-1
methyl benzilate

: 15521-18-3
2-(dimethylamino)propan-1-ol

: 94914-83-7
benzilic acid-(2-dimethylamino-propyl ester)

Conditions

Conditions	Yield
With sodium In benzene

: 31197-69-0
ethyl 2-cyclohexyl-2-hydroxy-2-phenylacetate

: 15521-18-3
2-(dimethylamino)propan-1-ol

: 94439-61-9
Cyclohexyl-phenyl-glykolsaeure-<2-dimethylamino-propylester>

Conditions

Conditions	Yield
With sodium In benzene

: 15521-18-3
2-(dimethylamino)propan-1-ol

: 75-03-6
ethyl iodide

: 543-20-4
succinoyl dichloride

: C18H38N2O4(2+)*2I(1-)

Conditions

Conditions	Yield
(i) HCl, CHCl3, (ii) /BRN= 505934/, EtOH; Multistep reaction;

...Expand

: 15521-18-3
2-(dimethylamino)propan-1-ol

: 75-03-6
ethyl iodide

: 543-20-4
succinoyl dichloride

: C18H38N2O4(2+)*2I(1-)

Conditions

Conditions	Yield
(i) HCl, CHCl3, (ii) /BRN= 505934/, EtOH; Multistep reaction;

...Expand

: 15521-18-3
2-(dimethylamino)propan-1-ol

: 106-95-6
allyl bromide

: 13388-32-4
2-Dimethylamino-1-allyloxy-propan

Conditions

Conditions	Yield
(i) NaH, toluene, (ii) /BRN= 605308/; Multistep reaction;

: 15521-18-3
2-(dimethylamino)propan-1-ol

: 109-92-2
ethyl vinyl ether

: 59276-18-5
Dimethyl-(1-methyl-2-vinyloxy-ethyl)-amine

Conditions

Conditions	Yield
With mercury(II) diacetate Heating;

: 15521-18-3
2-(dimethylamino)propan-1-ol

: 586-75-4
4-chlorobenzoyl chloride

: 4-Bromo-benzoic acid 2-dimethylamino-propyl ester

Conditions

Conditions	Yield
With pyridine at 23℃;

: 15521-18-3
2-(dimethylamino)propan-1-ol

: 79-44-7
N,N-Dimethylcarbamoyl chloride

: (RS)-2-dimethylamino-1-propyl N,N-dimethylcarbamate

Conditions

Conditions	Yield
With sodium hydride In toluene for 24h; Ambient temperature; Yield given;

1-Propanol,2-(dimethylamino)- Specification

The 1-Propanol,2-(dimethylamino)-, with the CAS registry number 15521-18-3, is also known as N,N-Dimethyl-2-aminopropan-1-ol. Its EINECS number is 239-558-7. This chemical's molecular formula is C₅H₁₃NO and molecular weight is 103.16. What's more, its IUPAC name is 2-(dimethylamino)propan-1-ol.

Physical properties of 1-Propanol,2-(dimethylamino)- are: (1)ACD/LogP: 0.02; (2)# of Rule of 5 Violations: 0; (3)#H bond acceptors: 2; (4)#H bond donors: 1; (5)#Freely Rotating Bonds: 3; (6)Polar Surface Area: 23.47 Å²; (7)Index of Refraction: 1.436; (8)Molar Refractivity: 30.42 cm³; (9)Molar Volume: 116.2 cm³; (10)Polarizability: 12.06×10^-24cm³; (11)Surface Tension: 29.5 dyne/cm; (12)Density: 0.887 g/cm³; (13)Flash Point: 32.1 °C; (14)Enthalpy of Vaporization: 43.26 kJ/mol; (15)Boiling Point: 133.8 °C at 760 mmHg; (16)Vapour Pressure: 3.62 mmHg at 25°C.

Uses of 1-Propanol,2-(dimethylamino)-: it can be used to produce N,N-dimethyl-acetamide at the temperature of 20 °C. It will need reagents KOH, air and solvent diethyl ether with the reaction time of 90 hours. The yield is about 73%.

1-Propanol,2-(dimethylamino)- can be used to produce N,N-dimethyl-acetamide at the temperature of 20 °C

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: CC(CO)N(C)C
(2)InChI: InChI=1S/C5H13NO/c1-5(4-7)6(2)3/h5,7H,4H2,1-3H3
(3)InChIKey: PBKGYWLWIJLDGZ-UHFFFAOYSA-N

Product Name

DL-2-DIMETHYLAMINO-1-PROPANOL

Synthetic route

1-Propanol,2-(dimethylamino)- Specification

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