Product Name

  • Name

    2-(4-Aminophenyl)ethylamine

  • EINECS 236-739-2
  • CAS No. 13472-00-9
  • Article Data33
  • CAS DataBase
  • Density 1.062 g/cm3
  • Solubility Insoluble in water.
  • Melting Point 28-31 °C(lit.)
  • Formula C8H12N2
  • Boiling Point 313.8 °C at 760 mmHg
  • Molecular Weight 136.197
  • Flash Point 140.9 °C
  • Transport Information UN 3259 8/PG 2
  • Appearance Light yellow solid or liquid
  • Safety 26-36/37/39-45-27
  • Risk Codes 34-20/21/22
  • Molecular Structure Molecular Structure of 13472-00-9 (2-(4-Aminophenyl)ethylamine)
  • Hazard Symbols CorrosiveC,IrritantXi
  • Synonyms Phenethylamine,p-amino- (8CI);(p-Aminophenyl)ethylamine;2-(4-Aminophenyl)phenethylamine;2-(p-Aminophenyl)ethylamine;4-(2-Aminoethyl)benzenamine;4-(2-Aminoethyl)phenylamine;4-Amino-b-phenylethylamine;4-Aminobenzeneethanamine;4-Aminophenylethylamine;NSC 299558;NSC 9060;p-(2-Aminoethyl)aniline;p-Aminophenethylamine;b-(p-Aminophenyl)ethylamine;
  • PSA 52.04000
  • LogP 2.05150

Synthetic route

p-aminophenylacetonitrile
3544-25-0

p-aminophenylacetonitrile

p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

Conditions
ConditionsYield
With hydrazine hydrate; nickel In ethanol at 50 - 55℃;100%
With hydrazine hydrate; nickel In ethanol at 50 - 55℃; Product distribution; Other aminoarylalkylnitriles. Object: selective reduction of the nitrile group.;100%
With methanol; cobalt(II) chloride; diborane for 0.5h; Ambient temperature;97.7%
2-(p-nitrophenyl)ethylamine
24954-67-4

2-(p-nitrophenyl)ethylamine

p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

Conditions
ConditionsYield
With hydrogen In methanol at 20℃; under 760.051 Torr;100%
With 5%-palladium/activated carbon; hydrogen In ethanol under 760.051 Torr;91%
With hydrogenchloride; tin
With palladium on activated charcoal; hydrogen
With palladium on activated charcoal; hydrogen
1-nitro-4-(2-nitroethyl)benzene
21473-45-0

1-nitro-4-(2-nitroethyl)benzene

p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

Conditions
ConditionsYield
With samarium diiodide; water; isopropylamine In tetrahydrofuran86%
4-Nitrophenylacetonitrile
555-21-5

4-Nitrophenylacetonitrile

p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

Conditions
ConditionsYield
With sodium tetrahydroborate; (-) In ethanol at 20℃; for 156h;77%
With acetic anhydride; platinum Hydrogenation.Erhitzen des Reaktionsprodukts mit wss.Salzsaeure;
With ethanol; nickel Hydrogenation;
1-azido-2-(4'-nitrophenyl)ethane
70079-91-3

1-azido-2-(4'-nitrophenyl)ethane

p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

Conditions
ConditionsYield
With hydrogenchloride; indium In tetrahydrofuran at 20℃; for 7h;63%
N-benzyloxycarbonyl-4-nitrophenethylamine
182252-00-2

N-benzyloxycarbonyl-4-nitrophenethylamine

A

p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

B

N-benzyloxycarbonyl-4-aminophenethylamine
159182-10-2

N-benzyloxycarbonyl-4-aminophenethylamine

C

4,4'-azobis(N-benzyloxycarbonyl)phenethylamine

4,4'-azobis(N-benzyloxycarbonyl)phenethylamine

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal; ethylenediamine In tetrahydrofuran at 20℃; under 760 Torr; for 8h; Hydrogenation;A n/a
B 60%
C n/a
(p-aminophenyl)alanine
2922-41-0

(p-aminophenyl)alanine

p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

Conditions
ConditionsYield
With pyridoxal 5'-phosphate; aromatic L-amino acid decarboxylase In various solvent(s) at 30℃; for 48h;28%
N-<2-(4-nitrophenyl)ethyl>phthalimide
101291-45-6

N-<2-(4-nitrophenyl)ethyl>phthalimide

p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

Conditions
ConditionsYield
With sodium sulfide; water
4-(2-(((methyl)carbonyl)amino)ethyl)aniline
40377-41-1

4-(2-(((methyl)carbonyl)amino)ethyl)aniline

p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

Conditions
ConditionsYield
With hydrogenchloride
N-<2-(4-nitrophenyl)ethyl>acetamide
6270-07-1

N-<2-(4-nitrophenyl)ethyl>acetamide

p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

Conditions
ConditionsYield
With hydrogenchloride; tin; ethanol nachfolgendes Eindampfen;
Multi-step reaction with 2 steps
1: iron; aq.-ethanolic HCl
2: aqueous HCl
View Scheme
With iron; acetic acid Eindampfen der alkalisch gemachten Loesung;
p-aminophenylacetonitrile
3544-25-0

p-aminophenylacetonitrile

cyclohexanol
108-93-0

cyclohexanol

A

p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

B

(4-amino-phenethyl)-cyclohexyl-amine
861337-37-3

(4-amino-phenethyl)-cyclohexyl-amine

C

bis-(4-amino-phenethyl)-amine
861318-82-3

bis-(4-amino-phenethyl)-amine

Conditions
ConditionsYield
at 90℃; Hydrogenation;
ethanol
64-17-5

ethanol

4-Nitrophenylacetonitrile
555-21-5

4-Nitrophenylacetonitrile

ethyl acetate
141-78-6

ethyl acetate

hydrogen

hydrogen

nickel

nickel

p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

Conditions
ConditionsYield
at 20℃;
tetralin
119-64-2

tetralin

4-Nitrophenylacetonitrile
555-21-5

4-Nitrophenylacetonitrile

nickel kieselguhr-catalyst

nickel kieselguhr-catalyst

A

p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

B

bis-(4-amino-phenethyl)-amine
861318-82-3

bis-(4-amino-phenethyl)-amine

Conditions
ConditionsYield
at 130℃; under 20 Torr; Hydrogenation;
4-nitro-phenethylamine hydrochloride

4-nitro-phenethylamine hydrochloride

p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

Conditions
ConditionsYield
With hydrogenchloride; palladium Hydrogenation.Behandeln des Reaktionsprodukts mit Kaliumcarbonat in wss.Natronlauge;
With hydrogenchloride; amalgamated zinc Behandeln des Reaktionsprodukts mit Kaliumcarbonat in wss.Natronlauge;
With hydrogenchloride; tin(ll) chloride Behandeln des Reaktionsprodukts mit Kaliumcarbonat in wss.Natronlauge;
p-aminophenylacetonitrile
3544-25-0

p-aminophenylacetonitrile

tetralin
119-64-2

tetralin

nickel kieselguhr

nickel kieselguhr

A

p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

B

bis-(4-amino-phenethyl)-amine
861318-82-3

bis-(4-amino-phenethyl)-amine

Conditions
ConditionsYield
at 130℃; Hydrogenation;
2-(4-nitrophenyl)ethylamine monohydrochloride
29968-78-3

2-(4-nitrophenyl)ethylamine monohydrochloride

p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 82 percent / Et3N / tetrahydrofuran / 17 h / 20 °C
2: H2 / Pd/C-ethylenediamine / tetrahydrofuran / 8 h / 20 °C / 760 Torr
View Scheme
With palladium 10% on activated carbon; ammonium formate In methanol Reflux;
methyl-N-(benzyl-methyl)-formamide
877-95-2

methyl-N-(benzyl-methyl)-formamide

p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
2: tin; hydrochloric acid; alcohol / nachfolgendes Eindampfen
View Scheme
Multi-step reaction with 2 steps
1: nitric acid / 0 °C
2: tin; hydrochloric acid; alcohol / nachfolgendes Eindampfen
View Scheme
phenethylamine
64-04-0

phenethylamine

p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 210 - 220 °C / durch Erhitzen zuletzt auf 290grad
3: tin; hydrochloric acid; alcohol / nachfolgendes Eindampfen
View Scheme
Multi-step reaction with 3 steps
1: 210 - 220 °C / durch Erhitzen zuletzt auf 290grad
2: nitric acid / 0 °C
3: tin; hydrochloric acid; alcohol / nachfolgendes Eindampfen
View Scheme
Multi-step reaction with 2 steps
1: hydrogenchloride; nitric acid / water / 20 °C
2: hydrogen; 5%-palladium/activated carbon / ethanol / 760.05 Torr
View Scheme
Multi-step reaction with 2 steps
1: sulfuric acid; nitric acid
2: palladium on activated charcoal; hydrogen
View Scheme
(4-nitrophenyl)ethyl bromide
5339-26-4

(4-nitrophenyl)ethyl bromide

p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: potassium carbonate / 150 °C
2: sodium sulfide; water
View Scheme
1-phenyl-2-bromoethane
103-63-9

1-phenyl-2-bromoethane

p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: Nitrierung
2: potassium carbonate / 150 °C
3: sodium sulfide; water
View Scheme
Multi-step reaction with 3 steps
1: glacial acetic acid; acetic acid anhydride; fuming nitric acid / <0
2: potassium carbonate / 150 °C
3: sodium sulfide; water
View Scheme
2-4-aminophenylethylcarbamic acid methyl ester
144222-20-8

2-4-aminophenylethylcarbamic acid methyl ester

p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

Conditions
ConditionsYield
With trifluorormethanesulfonic acid; trifluoroacetic acid at 70℃; Kinetics; Inert atmosphere;
4-(2-aminoethyl)-N-(tert-butoxycarbonyl)phenylamine
457631-44-6

4-(2-aminoethyl)-N-(tert-butoxycarbonyl)phenylamine

p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

Conditions
ConditionsYield
With trifluoroacetic acid In dichloromethane at 20℃; for 24h; Concentration;14.1 g
2-(4-nitrophenyl)ethanol
100-27-6

2-(4-nitrophenyl)ethanol

p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: hydrogen; palladium on activated charcoal / methanol / 12 h / 40 °C / 1500.15 Torr / Autoclave
2: triethanolamine / methanol / 12 h / 70 °C / Inert atmosphere
3: triethylamine / dichloromethane / 2 h / -5 - 20 °C
4: ammonium hydroxide / N,N-dimethyl-formamide / 5 h / 100 °C / Inert atmosphere
5: trifluoroacetic acid / dichloromethane / 24 h / 20 °C
View Scheme
Multi-step reaction with 5 steps
1: hydrogen; palladium on activated charcoal / methanol / 12 h / 40 °C / 1500.15 Torr / Autoclave
2: triethanolamine / methanol / 12 h / 70 °C / Inert atmosphere
3: triethylamine / dichloromethane / 2 h / 10 - 20 °C
4: ammonium hydroxide / N,N-dimethyl-formamide / 5 h / 80 °C / Inert atmosphere
5: trifluoroacetic acid / dichloromethane / 24 h / 20 °C
View Scheme
2-(4'-aminophenyl)ethyl alcohol
104-10-9

2-(4'-aminophenyl)ethyl alcohol

p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: triethanolamine / methanol / 12 h / 70 °C / Inert atmosphere
2: triethylamine / dichloromethane / 2 h / -5 - 20 °C
3: ammonium hydroxide / N,N-dimethyl-formamide / 5 h / 100 °C / Inert atmosphere
4: trifluoroacetic acid / dichloromethane / 24 h / 20 °C
View Scheme
Multi-step reaction with 4 steps
1: triethanolamine / methanol / 12 h / 70 °C / Inert atmosphere
2: triethylamine / dichloromethane / 2 h / 10 - 20 °C
3: ammonium hydroxide / N,N-dimethyl-formamide / 5 h / 80 °C / Inert atmosphere
4: trifluoroacetic acid / dichloromethane / 24 h / 20 °C
View Scheme
tert-butyl N-[4-(2-hydroxyethyl)phenyl]carbamate
104060-23-3

tert-butyl N-[4-(2-hydroxyethyl)phenyl]carbamate

p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: triethylamine / dichloromethane / 2 h / -5 - 20 °C
2: ammonium hydroxide / N,N-dimethyl-formamide / 5 h / 100 °C / Inert atmosphere
3: trifluoroacetic acid / dichloromethane / 24 h / 20 °C
View Scheme
Multi-step reaction with 3 steps
1: triethylamine / dichloromethane / 2 h / 10 - 20 °C
2: ammonium hydroxide / N,N-dimethyl-formamide / 5 h / 80 °C / Inert atmosphere
3: trifluoroacetic acid / dichloromethane / 24 h / 20 °C
View Scheme
2-[4-(tert-butoxycarbonylamino)phenyl]ethylmethanesulfonate

2-[4-(tert-butoxycarbonylamino)phenyl]ethylmethanesulfonate

p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: ammonium hydroxide / N,N-dimethyl-formamide / 5 h / 80 °C / Inert atmosphere
2: trifluoroacetic acid / dichloromethane / 24 h / 20 °C
View Scheme
4-(2-aminoethyl)benzenamine hydrochloride salt
102606-30-4

4-(2-aminoethyl)benzenamine hydrochloride salt

p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

Conditions
ConditionsYield
With sodium hydroxide In water0.51 g
p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

4,7,10,13-tetraoxa-16-azaheneicosanoic acid 21-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-17-oxo-2,5-dioxo-1-pyrrolidinyl ester

4,7,10,13-tetraoxa-16-azaheneicosanoic acid 21-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-17-oxo-2,5-dioxo-1-pyrrolidinyl ester

C29H47N5O7S

C29H47N5O7S

Conditions
ConditionsYield
With triethylamine In dichloromethane for 4h;100%
p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

4-(1H-1,2,4-triazol-1-yl)-7-(((N-Boc)piperidin-4-yl)methoxy)quinazoline

4-(1H-1,2,4-triazol-1-yl)-7-(((N-Boc)piperidin-4-yl)methoxy)quinazoline

tert-butyl 4-{[(4-{[2-(4-aminophenyl)ethyl]amino}quinazolin-7-yl)oxy]methyl}piperidine-1-carboxylate

tert-butyl 4-{[(4-{[2-(4-aminophenyl)ethyl]amino}quinazolin-7-yl)oxy]methyl}piperidine-1-carboxylate

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide at 20℃;100%
p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

α,α,α-trifluoro-o-diacetotoluidide
172217-04-8

α,α,α-trifluoro-o-diacetotoluidide

4-(2-(((methyl)carbonyl)amino)ethyl)aniline
40377-41-1

4-(2-(((methyl)carbonyl)amino)ethyl)aniline

Conditions
ConditionsYield
In ethanol at 0℃;98%
p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

tert-butyl 4-aminophenethylcarbamate
94838-59-2

tert-butyl 4-aminophenethylcarbamate

Conditions
ConditionsYield
In 1,4-dioxane98%
In tetrahydrofuran at 0 - 20℃; for 1h;98%
With triethylamine In dichloromethane at 20 - 24℃; for 16h; Reagent/catalyst; Solvent;98%
p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

Allyl chloroformate
2937-50-0

Allyl chloroformate

4-(2-aminoethyl)-N-(allylcarbonyloxy)phenylamine
1139884-80-2

4-(2-aminoethyl)-N-(allylcarbonyloxy)phenylamine

Conditions
ConditionsYield
With acetic acid In 1,4-dioxane; water pH=4.5; regioselective reaction;98%
With acetic acid In 1,4-dioxane; water at 20℃;69%
p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

1,3-diphenyl-2-propynone
7338-94-5

1,3-diphenyl-2-propynone

(Z)-3-((4-aminophenethyl)amino)-1,3-diphenylprop-2-en-1-one

(Z)-3-((4-aminophenethyl)amino)-1,3-diphenylprop-2-en-1-one

Conditions
ConditionsYield
In dimethyl sulfoxide at 20℃; for 5h; chemoselective reaction;98%
p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

2-(3-[N-tert-butoxycarbonylaminophenyl]amino)-4-chloro-6-cyclopentylamino-1,3,5-triazine
878203-48-6

2-(3-[N-tert-butoxycarbonylaminophenyl]amino)-4-chloro-6-cyclopentylamino-1,3,5-triazine

2-(2-[4-aminophenyl]ethylamino)-4-(3-[N-tert-butoxycarbonylaminophenyl]amino)-6-cyclopentylamino-1,3,5-triazine
878203-51-1

2-(2-[4-aminophenyl]ethylamino)-4-(3-[N-tert-butoxycarbonylaminophenyl]amino)-6-cyclopentylamino-1,3,5-triazine

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 20 - 60℃; for 20h;97%
p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

C35H48ClN3O10S

C35H48ClN3O10S

4-maleimidobutyric acid N-hydroxysuccinimide ester
80307-12-6

4-maleimidobutyric acid N-hydroxysuccinimide ester

C51H67ClN6O13S

C51H67ClN6O13S

Conditions
ConditionsYield
In aq. phosphate buffer; N,N-dimethyl acetamide for 2h; pH=8;97%
p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

9-benzoyl-9H-carbazole
19264-68-7

9-benzoyl-9H-carbazole

N-(4-aminophenethyl)benzamide
144765-53-7

N-(4-aminophenethyl)benzamide

Conditions
ConditionsYield
In tetrahydrofuran at 30℃; for 24h; chemoselective reaction;97%
p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

C15H16ClNO4
1338350-70-1

C15H16ClNO4

7-methoxy-8-butyloxy-2-oxo-1,2-dihydroquinoline-3-carboxylic acid 2-(4-amino-phenyl)ethylamide
1338350-75-6

7-methoxy-8-butyloxy-2-oxo-1,2-dihydroquinoline-3-carboxylic acid 2-(4-amino-phenyl)ethylamide

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃; for 16h;96%
p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

2-[4-([3-tert-butoxycarobnylaminophenyl]amino)-6-[2-[4-[4-([3-tert-butoxycarbonylaminophenyl]amino)-6-chloro[1,3,5]triazine-2-ylamino]phenyl]ethylamino][1,3,5]triazine-2-ylamino]ethanol
1192801-08-3

2-[4-([3-tert-butoxycarobnylaminophenyl]amino)-6-[2-[4-[4-([3-tert-butoxycarbonylaminophenyl]amino)-6-chloro[1,3,5]triazine-2-ylamino]phenyl]ethylamino][1,3,5]triazine-2-ylamino]ethanol

2-({4-[(3-aminophenyl)amino]-6-({2-[4-({4-[(3-aminophenyl)amino]-6-{[2-(4-aminophenyl)ethyl]amino}1,3,5-triazin-2-yl}amino)phenyl]ethyl}amino)-1,3,5-triazine-2-yl}amino)ethan-1-ol

2-({4-[(3-aminophenyl)amino]-6-({2-[4-({4-[(3-aminophenyl)amino]-6-{[2-(4-aminophenyl)ethyl]amino}1,3,5-triazin-2-yl}amino)phenyl]ethyl}amino)-1,3,5-triazine-2-yl}amino)ethan-1-ol

Conditions
ConditionsYield
With hydrogenchloride In 1,4-dioxane95%
p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

benzyl chloroformate
501-53-1

benzyl chloroformate

4-(2-aminoethyl)-N-(benzyloxycarbonyl)phenylamine
1139884-44-8

4-(2-aminoethyl)-N-(benzyloxycarbonyl)phenylamine

Conditions
ConditionsYield
With acetic acid In 1,4-dioxane; water at 20℃; pH=4.5; regioselective reaction;93%
at 20℃; regioselective reaction;81%
p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

3,5-di-tert-butylbenzoic acid
16225-26-6

3,5-di-tert-butylbenzoic acid

N-[2-(4-aminophenyl)ethyl]-3,5-di-tert-butyl-benzamide
1233488-05-5

N-[2-(4-aminophenyl)ethyl]-3,5-di-tert-butyl-benzamide

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 25℃; for 16h;93%
p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

1-iodo-3-isocyanatobenzene
23138-56-9

1-iodo-3-isocyanatobenzene

1-[2-(4-aminophenyl)ethyl]-3-(3-iodophenyl)urea
1206531-53-4

1-[2-(4-aminophenyl)ethyl]-3-(3-iodophenyl)urea

Conditions
ConditionsYield
In dichloromethane at 20℃; Cooling with ice;92%
p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

4-(N-maleimidomethyl)cyclohexane-1-carboxylic acid N-succinimidyl ester
64987-85-5

4-(N-maleimidomethyl)cyclohexane-1-carboxylic acid N-succinimidyl ester

C35H48ClN3O10S

C35H48ClN3O10S

C55H73ClN6O13S

C55H73ClN6O13S

Conditions
ConditionsYield
In aq. phosphate buffer; N,N-dimethyl acetamide for 2h; pH=8;92%
p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

C14H19NO6S2

C14H19NO6S2

A

C20H23N3

C20H23N3

B

C32H34N4

C32H34N4

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 120℃; for 20h; Temperature;A 91.5%
B 80.42 g
p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

2-(4-anilino-6-chloro-[1,3,5]triazin-2-ylamino)-ethanol
24799-62-0

2-(4-anilino-6-chloro-[1,3,5]triazin-2-ylamino)-ethanol

2-[2-(4-aminophenyl)ethylamino]-4-(2-hydroxyethylamino)-6-phenylamino-1,3,5-triazine
852673-26-8

2-[2-(4-aminophenyl)ethylamino]-4-(2-hydroxyethylamino)-6-phenylamino-1,3,5-triazine

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 60℃; for 20h;91%
p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

1-(phenylsulfonyl)-1H-benzo[d][1,2,3]triazole
4106-18-7

1-(phenylsulfonyl)-1H-benzo[d][1,2,3]triazole

N-<2-(p-aminophenyl)ethyl>benzenesulfonamide

N-<2-(p-aminophenyl)ethyl>benzenesulfonamide

Conditions
ConditionsYield
In tetrahydrofuran for 40h; Ambient temperature;90%
p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

N,N'-bis( tert-butoxycarbonyl)-1H-pyrazole-1-carboxamidine
152120-54-2, 862686-58-6, 1143572-00-2

N,N'-bis( tert-butoxycarbonyl)-1H-pyrazole-1-carboxamidine

C19H30N4O4

C19H30N4O4

Conditions
ConditionsYield
With acetic acid In 1,4-dioxane; water at 20℃; for 18h;90%
p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

(R)-2-hydroxy-2-phenylethyl 4-methylbenzenesulfonate
40434-87-5

(R)-2-hydroxy-2-phenylethyl 4-methylbenzenesulfonate

YM-208876
391901-45-4

YM-208876

Conditions
ConditionsYield
In acetonitrile at 70℃; for 10h;89.7%
p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

1-acetoxy-4-methylbenzene
140-39-6

1-acetoxy-4-methylbenzene

4-(2-(((methyl)carbonyl)amino)ethyl)aniline
40377-41-1

4-(2-(((methyl)carbonyl)amino)ethyl)aniline

Conditions
ConditionsYield
at 20℃; for 30h;89.7%
at 20℃; for 30h;89.7%
p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

acrylonitrile
107-13-1

acrylonitrile

3-(4-aminophenethyl)aminopropionitrile
1421487-29-7

3-(4-aminophenethyl)aminopropionitrile

Conditions
ConditionsYield
With Ps-AlCl3 at 20℃; for 2h; Michael Addition; regioselective reaction;89%
p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

(R)-4-(oxiran-2-yl)-2,8-bis(trifluoromethyl)quinoline
1292282-18-8

(R)-4-(oxiran-2-yl)-2,8-bis(trifluoromethyl)quinoline

2‐((4‐aminophenethyl)amino)‐1‐(2,8‐bis(trifluoromethyl)quinolin‐4‐yl)ethan‐1‐ol

2‐((4‐aminophenethyl)amino)‐1‐(2,8‐bis(trifluoromethyl)quinolin‐4‐yl)ethan‐1‐ol

Conditions
ConditionsYield
In ethanol at 130℃; for 0.5h; Microwave irradiation;89%
p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

(S)-4-(oxiran-2-yl)-2,8-bis(trifluoromethyl)quinoline
1292282-19-9

(S)-4-(oxiran-2-yl)-2,8-bis(trifluoromethyl)quinoline

2‐((4‐aminophenethyl)amino)‐1‐(2,8‐bis(trifluoromethyl)quinolin‐4‐yl)ethan‐1‐ol

2‐((4‐aminophenethyl)amino)‐1‐(2,8‐bis(trifluoromethyl)quinolin‐4‐yl)ethan‐1‐ol

Conditions
ConditionsYield
In ethanol at 130℃; for 0.5h; Microwave irradiation;89%
p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

ethyl trifluoroacetate,
383-63-1

ethyl trifluoroacetate,

N-[2-(4-aminophenyl)ethyl]-2,2,2-trifluoroacetamide
24954-62-9

N-[2-(4-aminophenyl)ethyl]-2,2,2-trifluoroacetamide

Conditions
ConditionsYield
In chloroform at 0 - 20℃; for 16h;89%
p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

acrylic acid methyl ester
292638-85-8

acrylic acid methyl ester

methyl 3-(4-aminophenethyl)aminopropanoate
1421487-28-6

methyl 3-(4-aminophenethyl)aminopropanoate

Conditions
ConditionsYield
With Ps-AlCl3 at 20℃; for 2h; Michael Addition; regioselective reaction;88%
p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

5-bromo-1,3-xylene
556-96-7

5-bromo-1,3-xylene

A

2-(4-aminophenyl)-N-(3,5-dimethylphenyl)ethylamine

2-(4-aminophenyl)-N-(3,5-dimethylphenyl)ethylamine

B

4-(2-aminoethyl)-N-(3,5-dimethylphenyl)aniline

4-(2-aminoethyl)-N-(3,5-dimethylphenyl)aniline

Conditions
ConditionsYield
With tris(dibenzylideneacetone)dipalladium (0); potassium carbonate; XPhos In tert-butyl alcohol at 100℃; for 22h;A n/a
B 87%
p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

2-(4-azidophenyl)ethan-1-amine

2-(4-azidophenyl)ethan-1-amine

Conditions
ConditionsYield
With sodium azide; sulfuric acid; sodium nitrite In water at 0℃; for 0.333333h;87%
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