2,3-Dichloro-1,4-naphthoquinone supplier

Name
2,3-Dichloro-1,4-naphthoquinone
EINECS 204-210-5
CAS No. 117-80-6
Article Data70
CAS DataBase
Density 1.54 g/cm³
Solubility 0.008 g/L in water
Melting Point 194-197 °C(lit.)
Formula C₁₀H₄Cl₂O₂
Boiling Point 304 °C at 760 mmHg
Molecular Weight 227.047
Flash Point 127.5 °C
Transport Information UN 2811 6.1/PG 3
Appearance yellow crystalline powder
Safety 26-60-61
Risk Codes 22-36/38-50/53
Molecular Structure
Hazard Symbols Xn; N
Synonyms 2,3-Dichloronaphthoquinone-1,4;2,3-Dichloronaphthoquinone;Sanquinon;1,4-Naphthalenedione, 2,3-dichloro-;1,4-Naphthalenedione,2,3-dichloro-;Algistat;1,4-Naphthoquinone, 2,3-dichloro-;EPA Pesticide Chemical Code 029601;USR 604;2,3-dichloronaphthalene-1,4-dione;US Rubber 604;CNQ;Phygon;2,3-Dichloro-1,4-naphthalenedione;Uniroyal;Dichlone;Phygon Seed Protectant;Dichloronaphthoquinone;2, 3-Dichloro-.alpha.-naphthoquinone;Quintar 540F;2,3-Dichloro-1, 4-naphthalenedione;Dichlone [BSI:ISO];2,3-Dichloro-1,4-naphthaquinone;Quintar;2, 3-Dichloronaphthoquinone;U.S. Rubber 604;
PSA 34.14000
LogP 2.75480

Synthetic route

: 1010-60-2
2-chloro-1,4-naphthoquinone

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

Conditions

Conditions	Yield
With pyridine; thionyl chloride In benzene for 3.5h; Heating;	88%
With chlorine; acetic acid
With chlorine; acetic acid at 95 - 100℃;	265 g

: 130-15-4
[1,4]naphthoquinone

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

Conditions

Conditions	Yield
With pyridine; thionyl chloride In benzene for 3.5h; Heating;	87%
With hydrogenchloride; sodium chlorate; tetrabutylammomium bromide In ethyl acetate at 50℃; for 20h;	73%
With iodine; acetic acid durch Chlorierung;

: 571-60-8
1,4-Dihydroxynaphthalene

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

Conditions

Conditions	Yield
With pyridine; thionyl chloride In benzene for 3h; Heating;	74%
Multi-step reaction with 3 steps 1: 92 percent / SOCl2 / benzene / 2 h / Heating 2: 71 percent / SCl2, S2Cl2, pyridine / benzene / 1.5 h / Heating 3: 88 percent / SOCl2, pyridine / benzene / 3.5 h / Heating View Scheme
Multi-step reaction with 2 steps 1: 92 percent / SOCl2 / benzene / 2 h / Heating 2: 87 percent / SOCl2, pyridine / benzene / 3.5 h / Heating View Scheme

: 2395-97-3
9,10-dimethoxyanthracene

A: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

B: 1010-60-2
2-chloro-1,4-naphthoquinone

Conditions

Conditions	Yield
With hydrogenchloride; iodosylbenzene; sodium hydrogencarbonate In diethyl ether for 0.5h; Chlorination; oxidation;	A 21% B 67%
With hydrogenchloride; sulfuric acid for 0.5h; Chlorination; oxidation;	A 31% B 36%

: 139719-08-7
2,3-Dichloro-N-p-tolylsulfonyl-1,4-naphthoquinonemonoimine

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

Conditions

Conditions	Yield
With water	22%

: 3669-52-1
4-acetyl-1-naphthol

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

Conditions

Conditions	Yield
With hydrogenchloride; dihydrogen peroxide In acetonitrile for 1h; Heating;	21%

: 91-20-3
naphthalene

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

Conditions

Conditions	Yield
With chromyl chloride; acetic acid

: 64-17-5
ethanol

: 2243-28-9
2,2,3,4,4-pentachloro-1-oxo-1,2,3,4-tetrahydronaphthaline

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

Conditions

Conditions	Yield
at 120 - 130℃;

: 90-15-3
α-naphthol

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

Conditions

Conditions	Yield
With hydrogenchloride; potassium chlorate
With sulfuric acid Verduennen mit Wasser, Zusatz von Salzsaeure und Eintragen von KClO3;
With sulfuric acid; chlorine; iron(II) sulfate; acetic acid at 10 - 20℃; zuletzt bei 100-120grad;
durch Sulfurierung und nachf. Behandlung mit Kaliumchlorat und Salzsaeure;
Multi-step reaction with 2 steps 1: glacial acetic acid; chlorine 2: diluted acetic acid / 120 - 130 °C / im Druckrohr View Scheme

: 84-86-6
4-amino-1-naphthalenesufonic acid

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

Conditions

Conditions	Yield
With sulfuric acid; chlorine; iron at 10 - 20℃; zuletzt bei 90grad;
With sulfuric acid; chlorine; iron(II) sulfate at 10 - 20℃; zuletzt bei 90grad;

: 2243-28-9
2,2,3,4,4-pentachloro-1-oxo-1,2,3,4-tetrahydronaphthaline

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

Conditions

Conditions	Yield
With ethanol at 120 - 130℃; im Druckrohr;
With acetic acid at 120 - 130℃; im Druckrohr;

: 605-69-6
1-hydroxy-2,4-dinitronaphthalene

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

Conditions

Conditions	Yield
With hydrogenchloride; potassium chlorate

: 605-69-6
1-hydroxy-2,4-dinitronaphthalene

A: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

B: 1010-60-2
2-chloro-1,4-naphthoquinone

Conditions

Conditions	Yield
With hydrogenchloride; potassium chlorate

: 71284-96-3
2,3-dichloro-[1]naphthol

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

Conditions

Conditions	Yield
With chromium(VI) oxide; acetic acid

: 1013-00-9
2,3-dichloro-1,2,3,4-tetrahydronaphthalene-1,4-dione

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

Conditions

Conditions	Yield
With sodium acetate; chlorine; acetic acid at 10 - 20℃; zuletzt bei Siedetemperatur;

: 94409-51-5
[1,4]naphthoquinone-mono-chlorimin

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

Conditions

Conditions	Yield
With hydrogenchloride; acetic acid at 25 - 30℃;

: 103754-44-5
2,3-dichloro-5,8-dihydro-naphthalene-1,4-diol

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

Conditions

Conditions	Yield
With chromium(VI) oxide

: 2243-28-9
2,2,3,4,4-pentachloro-1-oxo-1,2,3,4-tetrahydronaphthaline

: 64-19-7
acetic acid

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

Conditions

Conditions	Yield
at 120 - 130℃;

: 495-48-7
azoxybenzene

A: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

B: 122-66-7
diphenyl hydrazine

Conditions

Conditions	Yield
With sodium hydroxide; D-glucose

: 697-91-6
2,6-dichloro-1,4-benzoquinone

: 59637-68-2, 22062-59-5
2,3-Dichlor-1,4-naphthosemichinon

A: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

B: 34537-54-7
2,6-dichloro-p-benzoquinone anion radical

Conditions

Conditions	Yield
In gas at 150℃; Rate constant;

...Expand

: 107379-25-9
4-chloro-N-(3-chloro-4-oxonaphthalen-1(4H)-ylidene)benzenesulfonamide

A: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

B: 77302-41-1
2,2,3,3-Tetrachloro-1,2,3,4-tetrahydronaphthalene-1,4-dione

Conditions

Conditions	Yield
With water Yield given. Yields of byproduct given;

: Butyl-[2-(3-chloro-1,4-dioxo-1,4-dihydro-naphthalen-2-ylamino)-ethyl]-dimethyl-ammonium; bromide

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

Conditions

Conditions	Yield
With Tris-HCl buffer; dodecyl-N,N-dimethylamine N-oxide

: 2,3-Dichloro-[1,4]naphthoquinone; compound with phenylamine

A: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

B: 62-53-3
aniline

Conditions

Conditions	Yield
In dichloromethane at 21.4℃; Equilibrium constant;

: 2,3-Dichloro-[1,4]naphthoquinone; compound with phenylamine

A: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

B: 62-53-3
aniline

Conditions

Conditions	Yield
In dichloromethane at 21.4℃; Equilibrium constant;

: 2,3-Dichloro-[1,4]naphthoquinone; compound with p-tolylamine

A: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

B: 106-49-0
p-toluidine

Conditions

Conditions	Yield
In dichloromethane at 23.4℃; Equilibrium constant;

: 2,3-Dichloro-[1,4]naphthoquinone; compound with m-tolylamine

A: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

B: 108-44-1
1-amino-3-methylbenzene

Conditions

Conditions	Yield
In dichloromethane at 21.9℃; Equilibrium constant;

: 2,3-Dichloro-[1,4]naphthoquinone; compound with p-tolylamine

A: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

B: 106-49-0
p-toluidine

Conditions

Conditions	Yield
In dichloromethane at 23.4℃; Equilibrium constant;

: 2,3-Dichloro-[1,4]naphthoquinone; compound with m-tolylamine

A: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

B: 108-44-1
1-amino-3-methylbenzene

Conditions

Conditions	Yield
In dichloromethane at 21.9℃; Equilibrium constant;

: 2,3-Dichloro-[1,4]naphthoquinone; compound with o-tolylamine

A: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

B: 95-53-4
o-toluidine

Conditions

Conditions	Yield
In dichloromethane at 22.1℃; Equilibrium constant;

: 2,3-Dichloro-[1,4]naphthoquinone; compound with o-tolylamine

A: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

B: 95-53-4
o-toluidine

Conditions

Conditions	Yield
In dichloromethane at 22.1℃; Equilibrium constant;

: 110-91-8
morpholine

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 6336-72-7
2-chloro-3-morpholin-4-yl-[1,4]naphthoquinone

Conditions

Conditions	Yield
In water at 50℃; for 0.333333h;	100%
With water at 50℃; for 0.5h;	98%
With triethylamine In diethyl ether at 20℃; for 24h;	64%

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 62-53-3
aniline

: 1090-16-0
2-chloro-3-(phenylamino)naphthalene-1,4-dione

Conditions

Conditions	Yield
With water at 50℃; for 0.25h;	100%
Stage #1: aniline With triethylamine In water for 0.0833333h; Green chemistry; Stage #2: 2,3-Dichloro-1,4-naphthoquinone In water at 50 - 60℃; Green chemistry; regioselective reaction;	99%
In methanol Heating;	98%

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 4356-69-8
1,1-bis-(4-methoxyphenyl)ethylene

: 93404-12-7
2-chloro-3-<2,2-bis(p-methoxyphenyl)ethenyl>-1,4-naphthoquinone

Conditions

Conditions	Yield
With pyridine In tetrachloromethane for 1h; Quantum yield; Ambient temperature; Irradiation;	100%
With pyridine In tetrachloromethane for 0.0166667h; Ambient temperature; Irradiation;	100%

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 1074-82-4
potassium phtalimide

: 83167-46-8
2,2'-(1,4-dioxo-1,4-dihydronaphthalene-2,3-diyl)bis(isoindoline-1,3-dione)

Conditions

Conditions	Yield
In acetonitrile at 20℃; for 3h; Inert atmosphere; Reflux;	100%
In acetonitrile at 85℃; for 3h;	97%
In acetonitrile at 85℃; for 3h;	97%

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 533-31-3
Sesamol

: 2,3-(methylenedioxy)benzo[b]naphtho[2,3-d]furan-7,11-dione

Conditions

Conditions	Yield
With potassium hydroxide In pyridine at 90℃;	100%

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 99-03-6
1-(3-aminophenyl)ethanone

: 2-<(3'-acetylphenyl)amino>-3-chloro-1,4-naphthoquinone

Conditions

Conditions	Yield
In ethanol for 5h; Heating;	100%
In ethanol Reflux;	60%
With N,N-diethylaniline Reflux;

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 107-11-9
1-amino-2-propene

: 22272-29-3
2-(2-propenylamino)-3-chloronaphthalene-1,4-dione

Conditions

Conditions	Yield
In water at 20℃; for 0.5h;	100%
In ethanol for 6h;	95%
In ethanol at 20℃; for 60h;	80%

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

prenylindium sesquibromide: prenylindium sesquibromide

: 82214-83-3
2-chloro-3-(3-methylbut-2-enyl)naphthalene-1,4-dione

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at -23℃; for 3h;	100%

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 1159-54-2
tri(4-chlorophenyl)phosphine

: C28H16Cl3N4O2P

Conditions

Conditions	Yield
Stage #1: 2,3-Dichloro-1,4-naphthoquinone With sodium azide In ethanol at 20℃; for 1h; Substitution; Stage #2: tri(4-chlorophenyl)phosphine Cyclization;	100%

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 5720-07-0
4-methoxyphenylboronic acid

: 50982-55-3
2,3-bis(4-methoxyphenyl)naphthalene-1,4-dione

Conditions

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In water; benzene for 4h; Suzuki coupling; Heating;	100%

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 623-51-8
ethyl 2-sulfanylacetate

: 916250-47-0
ethyl 2-(3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-ylthio)acetate

Conditions

Conditions	Yield
With water at 50℃; for 2h;	100%
In water at 50℃; for 2h;	100%
In ethanol at 80 - 90℃;	97%

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 121-52-8
3-nitrophenylsulfonamide

: 1610042-49-3
N-(3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-3-nitrobenzenesulfonamide

Conditions

Conditions	Yield
With caesium carbonate In N,N-dimethyl-formamide at 20℃; Sealed tube; Microwave irradiation;	100%

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 106-49-0
p-toluidine

: 62101-46-6
TW-69

Conditions

Conditions	Yield
With cerium(III) chloride heptahydrate In ethanol at 20℃;	99%
In water Reflux; Green chemistry;	98%
In water Reflux;	98%

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 123-30-8
4-amino-phenol

: 64897-00-3
TW-73

Conditions

Conditions	Yield
In ethanol at 20 - 60℃; for 16h;	99%
In methanol at 20℃; for 10h;	97%
Stage #1: 4-amino-phenol With triethylamine In water for 0.0833333h; Green chemistry; Stage #2: 2,3-Dichloro-1,4-naphthoquinone In water at 50 - 60℃; Green chemistry; regioselective reaction;	96%

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 1679-18-1
4-Chlorophenylboronic acid

: 2,3-bis-(4-chloro-phenyl)-[1,4]naphthoquinone

Conditions

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In water; benzene for 6h; Suzuki coupling; Heating;	99%

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: bis(tetraetylammonium) bis(thioxo-1,3-dithiole-4,5-dithiolato)zincate(II)

: 180385-47-1
2-Thioxo-1,3,4,11-tetrathia-cyclopenta[b]anthracene-5,10-dione

Conditions

Conditions	Yield
In acetone at 20℃;	99%

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 106-44-5
p-cresol

: 2-chloro-3-(p-tolyloxy)-1,4-naphthoquinone

Conditions

Conditions	Yield
Stage #1: p-cresol With laundry detergent (Ariel) In water for 0.0833333h; Micellar solution; Stage #2: 2,3-Dichloro-1,4-naphthoquinone In water at 60℃; for 0.5h; Micellar solution; chemoselective reaction;	99%
Stage #1: p-cresol With Ariel laundry detergent In water for 0.0833333h; Stage #2: 2,3-Dichloro-1,4-naphthoquinone In water at 60℃; for 0.5h; chemoselective reaction;	99%
With caesium carbonate In tetrahydrofuran at 20℃; for 76h;	95%

: 123-75-1
pyrrolidine

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 2-chloro-3-(pyrrolidin-1-yl)naphthalene-1,4-dione

Conditions

Conditions	Yield
With water at 20℃; for 0.166667h;	99%
In water at 20℃; for 0.166667h;	99%

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 56445-08-0
3-amino-N-ethylbenzenesulfonamide

: 1241892-00-1
C18H15ClN2O4S

Conditions

Conditions	Yield
In ethanol; water at 120℃; for 72h;	99%

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 75105-48-5
N,N'-dimesitylformamidine

: 1,3-dimesityl-4,5-naphthquino-imidazolium chloride

Conditions

Conditions	Yield
Stage #1: 2,3-Dichloro-1,4-naphthoquinone; N,N'-dimesitylformamidine In acetonitrile at 110℃; for 48h; Sealed; Stage #2: With sodium hydrogencarbonate at 20 - 60℃; for 16h;	99%

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 64-04-0
phenethylamine

: 6307-22-8
2-chloro-3-(phenethylamino)naphthalene-1,4-dione

Conditions

Conditions	Yield
In acetonitrile at 20℃; for 1.5h;	99%
In ethanol at 20℃;	76%
In ethanol Reflux;	62%
In ethanol at 20℃; for 3h;	48.4%

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 108-91-8
cyclohexylamine

: 84349-14-4
2-chloro-3-(cyclohexylamino)naphthalene-1,4-dione

Conditions

Conditions	Yield
In ethanol at 20℃; for 6h; chemoselective reaction;	99%
In acetonitrile at 20℃; for 1.5h;	98%
With triethylamine In diethyl ether at 20℃; for 24h;	75%

: 110-89-4
piperidine

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 1221-13-2
2-chloro-3-piperidyl-1,4-naphthoquinone

Conditions

Conditions	Yield
With water at 20℃; for 0.166667h;	98%
In water at 20℃; for 0.166667h;	98%
With triethylamine In diethyl ether at 20℃; for 24h;	75%
With ethanol

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 63-74-1
sulfanilamide

: 6949-34-4
4-((3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)amino)benzenesulfonamide

Conditions

Conditions	Yield
In water for 3h; Reflux;	98%
In ethanol at 115℃; for 72h;	38.9%
With acetic acid; N,N-diethylaniline
In ethanol Reflux;

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 106-50-3
1,4-phenylenediamine

: 92796-77-5
2-(4-amino-anilino)-3-chloro-[1,4]naphthoquinone

Conditions

Conditions	Yield
In DMF (N,N-dimethyl-formamide) at 20℃; for 2h;	98%
With ethanol
In water; N,N-dimethyl-formamide
In ethanol Reflux;

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 2846-89-1
4,5-diaminopyridine-6<1H>-thione

: 106719-13-5
11-amino-6-chlorobenzo-8,10-diazaphenothiazin-5-one

Conditions

Conditions	Yield
With sodium carbonate In chloroform for 3.5h; Heating;	98%

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 99-98-9
4-amino-N,N-dimethylaniline

: 42262-96-4
2-chloro-3-(4-N,N-dimethylaminoanilino)-1,4-naphthoquinone

Conditions

Conditions	Yield
In ethanol at 20℃; for 5h;	98%

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 371-40-4
4-fluoroaniline

: 2-chloro-3-((4-fluorophenyl)amino)naphthalene-1,4-dione

Conditions

Conditions	Yield
In methanol Reflux;	98%
With cerium(III) chloride In ethanol at 65 - 70℃;	95%
With sodium carbonate In ethanol at 20℃; for 6h;	88.7%

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 2365-48-2
Methyl thioglycolate

: methyl 2-(3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-ylthio)acetate

Conditions

Conditions	Yield
In water at 20℃; for 1h;	98%
In ethanol at 80 - 90℃;

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 150-19-6
O-methylresorcine

: 2-chloro-3-(3-methoxyphenoxy)-1,4-naphthoquinone

Conditions

Conditions	Yield
With caesium carbonate In tetrahydrofuran at 20℃; for 20h;	98%

2,3-Dichloro-1,4-naphthoquinone Consensus Reports

Reported in EPA TSCA Inventory.

2,3-Dichloro-1,4-naphthoquinone Specification

The 2,3-Dichloro-1,4-naphthoquinone, with the CAS registry number 117-80-6 and EINECS registry number 204-210-5, has the systematic of 2,3-dichloronaphthalene-1,4-dione. And the molecular formula of this chemical is C₁₀H₄Cl₂O₂. It is a kind of yellow fine crystalline powder, and belongs to the product category of Intermediates of Dyes and Pigments. What's more, it is used as agricultural fungicide.

The physical properties of 2,3-Dichloro-1,4-naphthoquinone are as following: (1)ACD/LogP: 2.35; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.35; (4)ACD/LogD (pH 7.4): 2.35; (5)ACD/BCF (pH 5.5): 36.07; (6)ACD/BCF (pH 7.4): 36.07; (7)ACD/KOC (pH 5.5): 453.11; (8)ACD/KOC (pH 7.4): 453.11; (9)#H bond acceptors: 2; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 0; (12)Polar Surface Area: 34.14 Å²; (13)Index of Refraction: 1.634; (14)Molar Refractivity: 52.57 cm³; (15)Molar Volume: 146.9 cm³; (16)Polarizability: 20.84×10^-24cm³; (17)Surface Tension: 55.3 dyne/cm; (18)Density: 1.54 g/cm³; (19)Flash Point: 127.5 °C; (20)Enthalpy of Vaporization: 54.44 kJ/mol; (21)Boiling Point: 304 °C at 760 mmHg; (22)Vapour Pressure: 0.000897 mmHg at 25°C.

Preparation of 2,3-Dichloro-1,4-naphthoquinone: It can be prepared by the chlorination of 1,4 - naphthoquinone. The reaction will need will occur in the alcohols, phenols and hydrocarbons solvent. And the catalyst ferrous powder or iron chloride.

Uses of 2,3-Dichloro-1,4-naphthoquinone: It can react with 5-methyl-benzene-1,3-diol to produce 3-hydroxy-1-methyl-benzo[b]naphtho[2,3-d]furan-6,11-quinone. This reaction will need reagent NaOEt, and the solvent ethanol. And the yield is about 60%.

2,3-Dichloro-1,4-naphthoquinone can react with 5-methyl-benzene-1,3-diol to produce 3-hydroxy-1-methyl-benzo[b]naphtho[2,3-d]furan-6,11-quinone

You should be cautious while dealing with this chemical. It irritates eyes, respiratory system and skin, and it is also harmful if swallowed. What's more, it is very toxic to aquatic organisms, and may cause long-term adverse effects in the aquatic environment. Therefore, you had better take the following instructions: This material and/or its container must be disposed of as hazardous waste; Avoid release to the environment. Refer to special instructions safety data sheet; In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1)SMILES: O=C2c1c(cccc1)C(=O)C(/Cl)=C2/Cl
(2)InChI: InChI=1/C10H4Cl2O2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H
(3)InChIKey: SVPKNMBRVBMTLB-UHFFFAOYAD

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Source
mouse	LD50	intraperitoneal	30mg/kg (30mg/kg)	Journal of Medicinal Chemistry. Vol. 26, Pg. 570, 1983.
mouse	LD50	oral	440mg/kg (440mg/kg)	"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 47, 1982.
rabbit	LD50	skin	500mg/kg (500mg/kg)	"Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc of Chemistry, 1983-86Vol. A137, Pg. 1983,
rat	LD50	oral	160mg/kg (160mg/kg)	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 16(5), Pg. 52, 1972.

Product Name

2,3-Dichloro-1,4-naphthoquinone

Synthetic route

2,3-Dichloro-1,4-naphthoquinone Consensus Reports

2,3-Dichloro-1,4-naphthoquinone Specification

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