2,5-Dichloroaniline supplier

Name
2,5-Dichloroaniline
EINECS 202-455-2
CAS No. 95-82-9
Article Data72
CAS DataBase
Density 1.401 g/cm³
Solubility water: 0.56 g/L (20 °C)
Melting Point 48 °C
Formula C₆H₅Cl₂N
Boiling Point 250.999 °C at 760 mmHg
Molecular Weight 162.018
Flash Point 100.361 °C
Transport Information UN 3442 6.1/PG 2
Appearance light brown solid
Safety 28-36/37-45-60-61-28
Risk Codes 23/24/25-33-50/53
Molecular Structure
Hazard Symbols T,N
Synonyms Lake Scarlet GG Base;Hiltonil Fast Scarlet 2G Base;Azoene Fast Scarlet 2G Base;Naphtoelan Fast Scarlet GG Base;Fast scarlet 2g base;Naphtoelan fast scarlet GG salt;Amarthol fast scarlet GG salt;Mitsui scarlet GG salt;CI Azoic Diazo Component 3;Symulon scarlet 2g salt;Kayaku Scarlet GG Base;Azogene Fast Scarlet GGC;Spectrolene Scarlet 2G;
PSA 26.02000
LogP 3.15680

Synthetic route

: 89-61-2
2,5-dichloronitrobenzene

: 95-82-9
2,5 dichloroaniline

Conditions

Conditions	Yield
With hydrogen; zinc dibromide; palladium on activated charcoal In ethyl acetate under 760 Torr;	100%
	99%
With platinum on activated charcoal; hydrogen at 60℃; for 1h; Temperature; Inert atmosphere; Autoclave; Supercritical conditions;	99.4%

: 106-46-7
para-dichlorobenzene

: 95-82-9
2,5 dichloroaniline

Conditions

Conditions	Yield
Stage #1: para-dichlorobenzene With sulfuric acid; nitric acid Stage #2: With platinum on activated charcoal; hydrogen In acetic acid under 3102.97 Torr;	95%
With ammonium hydroxide; bis(acetylacetonate)oxovanadium; tetrabutylammomium bromide; dihydrogen peroxide In acetonitrile at 90℃; for 5h; Reagent/catalyst; Solvent; Time; Molecular sieve;	57%
Multi-step reaction with 2 steps 1: H2SO4; HNO3 2: 88.9 percent / aq. H2SO4 / ethanol / 48 - 50 °C / Electrochemical reaction View Scheme
Multi-step reaction with 2 steps 1: bei der Nitrierung 2: tin; hydrochloric acid View Scheme

: 135145-90-3
2,5-dichlorobenzeneboronic acid

: 95-82-9
2,5 dichloroaniline

Conditions

Conditions	Yield
With copper(I) oxide; ammonium hydroxide; air In methanol at 20℃; for 20h;	89%

: 6626-75-1
N-(2,5-dichlorophenyl)benzamide

: 95-82-9
2,5 dichloroaniline

Conditions

Conditions	Yield
With sulfuric acid for 3h; Heating;	82%

: 110-86-1
pyridine

: 305-15-7
(2,5-dichlorophenyl)hydrazine

A: 95-82-9
2,5 dichloroaniline

B: 106-46-7
para-dichlorobenzene

C: 4381-30-0
2-(2,5-dichlorophenyl)pyridine

D: 4467-14-5
4-(2,5-Dichloro-phenyl)-pyridine

Conditions

Conditions	Yield
With KO2 for 10h; Ambient temperature; Yield given. Further byproducts given;	A 6% B 59% C n/a D n/a

...Expand

: 305-15-7
(2,5-dichlorophenyl)hydrazine

A: 95-82-9
2,5 dichloroaniline

B: 106-46-7
para-dichlorobenzene

C: 4381-30-0
2-(2,5-dichlorophenyl)pyridine

D: 4467-14-5
4-(2,5-Dichloro-phenyl)-pyridine

Conditions

Conditions	Yield
With KO2 In pyridine for 10h; Ambient temperature; Further byproducts given;	A 6% B 59% C n/a D n/a

...Expand

: 588-07-8
3-Chloroacetanilide

A: 95-82-9
2,5 dichloroaniline

B: 95-76-1
m,p-dichloroaniline

Conditions

Conditions	Yield
With acetic acid Durch Chlorieren und Destillation des Reaktionsproduktes mit Natronlauge;
With acetic acid Durch Chlorieren;

: 29551-86-8
N-chloro-m-chloroacetanilide

A: 95-82-9
2,5 dichloroaniline

B: 95-76-1
m,p-dichloroaniline

Conditions

Conditions	Yield
With acetic acid Verseifen des Reaktionsproduktes;
With acetic acid und Verseifung des Reaktionsproduktes;

: 67083-41-4
1,4-dichloro-2-nitroso-benzene

: 124-41-4
sodium methylate

A: 95-82-9
2,5 dichloroaniline

B: 961-28-4
bis-(2,5-dichloro-phenyl)-diazene-N-oxide

...Expand

: 3032-32-4
3,6-dichloroanthranilic acid

: 95-82-9
2,5 dichloroaniline

Conditions

Conditions	Yield
at 230 - 240℃;

: 3032-32-4
3,6-dichloroanthranilic acid

A: 95-82-9
2,5 dichloroaniline

B: 15719-64-9, 15719-76-3, 97762-63-5
methylammonium carbonate

Conditions

Conditions	Yield
at 230 - 240℃;

: 2,5-dichloro-4-(2,5-dichloro-phenylazo)-aniline

A: 95-82-9
2,5 dichloroaniline

B: 20103-09-7
2,5-dichloro-1,4-phenylenediamine

Conditions

Conditions	Yield
bei der Reduktion;

: N,N-diethyl-4-(2,5-dichloro-phenylazo)-2-methyl-aniline

A: 95-82-9
2,5 dichloroaniline

B: 2628-71-9
N,N-diethyl-2-methyl-p-phenylenediamine

Conditions

Conditions	Yield
bei der Reduktion;

: 71-23-8
propan-1-ol

: 6819-41-6
sodium n-propoxide

: 89-61-2
2,5-dichloronitrobenzene

: 71-43-2
benzene

A: 95-82-9
2,5 dichloroaniline

B: 99586-92-2
N-(2,5-dichloro-phenyl)-alanine

...Expand

: 141-52-6
sodium ethanolate

: 89-61-2
2,5-dichloronitrobenzene

: 71-43-2
benzene

A: 95-82-9
2,5 dichloroaniline

B: 961-28-4
bis-(2,5-dichloro-phenyl)-diazene-N-oxide

...Expand

: 89-61-2
2,5-dichloronitrobenzene

A: 95-82-9
2,5 dichloroaniline

B: 43192-05-8
N-(2,5-dichloro-phenyl)-hydroxylamine

Conditions

Conditions	Yield
With sodium hydrogensulfide; water; calcium chloride

: 8-(2,5-dichloro-phenylazo)-1,3-dimethyl-3,7-dihydro-purine-2,6-dione

Na2S2O4: Na2S2O4

aqueous alkali: aqueous alkali

A: 95-82-9
2,5 dichloroaniline

B 8-amino-theophylline: 8-amino-theophylline

...Expand

: 64-17-5
ethanol

: 53847-61-3
5-methyl-2-phenyl-2H-pyrazole-3,4-dione 4-[(2,5-dichloro-phenyl)-hydrazone]

: 64-19-7
acetic acid

zinc dust: zinc dust

A: 95-82-9
2,5 dichloroaniline

B rubazonic acid: rubazonic acid

Conditions

Conditions	Yield
durch Oxydation an der Luft in Gegenwart von Eisenchlorid;

...Expand

: 7647-01-0
hydrogenchloride

: 98-95-3
nitrobenzene

: 95-82-9
2,5 dichloroaniline

Conditions

Conditions	Yield
at 245℃;

: 64-17-5
ethanol

: 89-61-2
2,5-dichloronitrobenzene

Raney nickel: Raney nickel

: 95-82-9
2,5 dichloroaniline

Conditions

Conditions	Yield
at 50 - 100℃; Hydrogenation;

...Expand

: 7647-01-0
hydrogenchloride

: 89-61-2
2,5-dichloronitrobenzene

tin: tin

: 95-82-9
2,5 dichloroaniline

...Expand

: 7647-01-0
hydrogenchloride

: 893-39-0
2,5,2',5'-tetrachlorodiazoaminobenzene

A: 95-82-9
2,5 dichloroaniline

B: 87-87-6
2,3,5,6-tetrachlorobenzene-1,4-diol

Conditions

Conditions	Yield
at 130℃;

...Expand

: 7647-01-0
hydrogenchloride

: 893-39-0
2,5,2',5'-tetrachlorodiazoaminobenzene

tin dichloride: tin dichloride

A: 95-82-9
2,5 dichloroaniline

B: 305-15-7
(2,5-dichlorophenyl)hydrazine

...Expand

: 7782-50-5
chlorine

: 108-42-9
3-chloro-aniline

A: 95-82-9
2,5 dichloroaniline

B: 634-67-3
2,3,4-trichloroaniline

C: 95-76-1
m,p-dichloroaniline

D: 636-30-6
2,4,5-trichloroaniline

...Expand

: 89-61-2
2,5-dichloronitrobenzene

alcoholic potash: alcoholic potash

A: 95-82-9
2,5 dichloroaniline

B: 89-64-5
p-chloro-o-nitrophenol

C: 961-28-4
bis-(2,5-dichloro-phenyl)-diazene-N-oxide

...Expand

: 106-46-7
para-dichlorobenzene

SO2: SO2

: 95-82-9
2,5 dichloroaniline

: 588-07-8
3-Chloroacetanilide

: 95-82-9
2,5 dichloroaniline

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: KHCO3; hypochlorous acid 2: glacial acetic acid / und Verseifung des Reaktionsproduktes View Scheme

: 71-43-2
benzene

: 95-82-9
2,5 dichloroaniline

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: iodine; chlorine 2: bei der Nitrierung 3: tin; hydrochloric acid View Scheme

: 108-42-9
3-chloro-aniline

: 95-51-2
2-Chloroaniline

: 95-82-9
2,5 dichloroaniline

Conditions

Conditions	Yield
With aniline

: 95-82-9
2,5 dichloroaniline

: 89-25-8
edaravone

: 6407-75-6
pigment yellow 10

Conditions

Conditions	Yield
Stage #1: 2,5 dichloroaniline With hydrogenchloride; sodium nitrite In water at 20℃; for 0.166667h; Stage #2: 3-methyl-1-phenylpyrazolin-5-(4H)-one In water at 20℃; for 0.166667h;	99%

: 19735-89-8
3-methyl-1-phenylpyrazolin-5(4H)-one

: 95-82-9
2,5 dichloroaniline

: 6407-75-6
pigment yellow 10

Conditions

Conditions	Yield
Stage #1: 2,5 dichloroaniline With hydrogenchloride; sodium nitrite In water at 20℃; for 0.333333h; Green chemistry; Stage #2: 3-methyl-1-phenylpyrazolin-5(4H)-one In water at 20℃; for 0.166667h; Green chemistry;	99%

: tetrafluoroboric acid

: 95-82-9
2,5 dichloroaniline

: 2,5-dichloroaniline diazonium fluoroboric salt

Conditions

Conditions	Yield
Stage #1: 2,5 dichloroaniline With hydrogenchloride; acetic acid; sodium nitrite In water at 0 - 50℃; Stage #2: tetrafluoroboric acid In water at 5℃;	98.7%

: 95-82-9
2,5 dichloroaniline

: 74220-11-4
2,5-dichloroanilinium hydrogen sulfate

Conditions

Conditions	Yield
With sulfuric acid In dichloromethane	98.56%

: 95-82-9
2,5 dichloroaniline

: 27761-65-5
2,4-dibromo-3,6-dichloroaniline

Conditions

Conditions	Yield
With bromine In water at 20℃; for 0.166667h;	98%
With bromine
With N-Bromosuccinimide In tetrahydrofuran at 20℃; for 2h;
With bromine at 20 - 25℃; for 0.0333333h; pH=8.5 - 9; aq. buffer;

: 95-82-9
2,5 dichloroaniline

: 79607-22-0, 70271-77-1
6-chloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid ethyl ester

: 1636164-11-8
6-chloro-4-oxo-N'-(2,5-dichlorophenyl)-1,4-dihydroquinoline-3-carboxamide

Conditions

Conditions	Yield
In diphenylether at 210℃; for 1h;	98%

: 95-82-9
2,5 dichloroaniline

: 81386-60-9
1-hydroxy-9,9-dimethoxy-10-anthrone

: 1-hydroxy-9-(2,5-dichlorophenylimino)-10-anthrone

Conditions

Conditions	Yield
In toluene for 18h; Reflux;	98%

: 95-82-9
2,5 dichloroaniline

: 89-61-2
2,5-dichloronitrobenzene

Conditions

Conditions	Yield
With fluoro alcohol In water; ethyl acetate; acetonitrile at -20℃; for 0.0833333h;	97%

: 95-82-9
2,5 dichloroaniline

: 140-89-6
potassium ethyl xanthogenate

: 5331-91-9
5-chloro-2-mercaptobenzothiazole

Conditions

Conditions	Yield
In dimethyl sulfoxide at 160℃;	97%
In N,N-dimethyl-formamide at 120℃; for 0.2h; microwave irradiation;	93%
for 0.0833333h; Microwave irradiation;	79%

: sodium molybdate

: 75-77-4
chloro-trimethyl-silane

: 95-82-9
2,5 dichloroaniline

: 339550-51-5
Mo(VI)[(N-2,5-Cl3C6H2)2Cl2(dimethoxyethane)]

Conditions

Conditions	Yield
With triethylamine In 1,2-dimethoxyethane byproducts: [(CH3)3Si]2O, NaCl, (C2H5)3NHCl; (Ar), mixed with suspn. of Mo complex, treated with chloromethylsilane, stirred under reflux for 18 h, cooled to room temp.; filtered, washed (DME), evapd.(vac.), cooled to 0°C, elem. anal.,NMR, MAS, XRD;	97%

...Expand

: 95-82-9
2,5 dichloroaniline

: 99421-72-4
1-phenylethyl 2,2,2-trichloroacetimidate

: 1036572-20-9
2,5-dichloro-N-(1-phenylethyl)aniline

Conditions

Conditions	Yield
With camphor-10-sulfonic acid In dichloromethane at 20℃; for 24h; Reagent/catalyst; Inert atmosphere;	97%

: 95-82-9
2,5 dichloroaniline

: 532-55-8
Benzoyl isothiocyanate

: 6281-57-8
N-(2,5-dichlorophenyl)-N'-benzoylthiocarbamide

Conditions

Conditions	Yield
In tetrahydrofuran at 60 - 65℃; for 0.166667h; Microwave irradiation;	96%
In acetone	79%
In acetone
In acetone

: 95-82-9
2,5 dichloroaniline

: 66224-70-2
3-(trimethylsilyl)propynoyl chloride

: N-(2,5-dichlorophenyl)-3-(trimethylsilyl)prop-2-ynamide

Conditions

Conditions	Yield
With pyridine In diethyl ether at -50℃; for 1h; Acylation;	96%
In diethyl ether at 25℃; for 1h;

: 64-18-6
formic acid

: 95-82-9
2,5 dichloroaniline

: 6639-55-0
N-(2,5-dichlorophenyl)formamide

Conditions

Conditions	Yield
at 20℃; for 4h; Green chemistry;	95%
at 20℃; for 3.33333h; Irradiation;	95%
at 20℃; for 72h;	67%

: 95-82-9
2,5 dichloroaniline

: 1435-50-3
2-bromo-1,4-dichlorobenzene

Conditions

Conditions	Yield
Stage #1: 2,5 dichloroaniline With hydrogen bromide; sodium nitrite In water at -5 - 0℃; for 0.0833333h; Stage #2: With hydrogen bromide; copper(I) bromide In water at 20 - 50℃; for 0.75h;	95%
Diazotization.Behandlung der Diazoniumsalz-Loesung mit CuBr und HBr;

: 95-82-9
2,5 dichloroaniline

: 348-59-4
1,4-dichloro-2-fluorobenzene

Conditions

Conditions	Yield
Stage #1: 2,5 dichloroaniline With hydrogenchloride; fluoroboric acid; sodium nitrite In water at 25℃; for 0.00555556h; Balz-Schiemann Reaction; Stage #2: In 1,2-dichloro-benzene at 200℃; for 0.0166667h; Balz-Schiemann Reaction;	95%
With hydrogenchloride; tetrafluoroboric acid; sodium nitrite Erhitzen des Reaktionsprodukts;

: 95-82-9
2,5 dichloroaniline

: 893-39-0
2,5,2',5'-tetrachlorodiazoaminobenzene

Conditions

Conditions	Yield
With hydrogenchloride; sodium nitrite In water at 0 - 20℃; for 3h;	95%
With hydrogenchloride; sodium acetate; sodium nitrite
Stage #1: 2,5 dichloroaniline With hydrogenchloride; sodium nitrite In water at 0 - 5℃; for 0.333333h; Stage #2: 2,5 dichloroaniline In water at 0 - 5℃; for 0.0833333h;

: 95-82-9
2,5 dichloroaniline

: 110-13-4
2,5-hexanedione

: N-(2′,5′-dichlorophenyl)-2,5-dimethylpyrrole

Conditions

Conditions	Yield
With calcium(II) chloride dihydrate In neat (no solvent) for 0.166667h; Paal-Knorr Pyrrole Synthesis; Microwave irradiation; Green chemistry;	95%
With Cl(1-)C5H14NO(1+)3ZnCl2 In neat (no solvent) at 20℃; for 0.166667h; Paal-Knorr Pyrrole Synthesis; Sealed tube; Sonication; Green chemistry;	86%
With MIL-53(Al) In neat (no solvent) at 80℃; for 0.5h; Paal-Knorr Pyrrole Synthesis; Sonication;	85%

: 95-82-9
2,5 dichloroaniline

A: 4571-24-8
1,4-dibromo-2,5-dichlorobenzene

B: 73557-61-6
1,2,4-tribromo-3,6-dichlorobenzene

Conditions

Conditions	Yield
With tert.-butylnitrite; bromine; copper(ll) bromide In acetonitrile at 50℃; for 0.25h;	A 2% B 95%

: 95-82-9
2,5 dichloroaniline

: 5147-80-8
[Bis(methylthio)methylene]malononitrile

: 2-[(2,5-Dichloro-phenylamino)-methylsulfanyl-methylene]-malononitrile

Conditions

Conditions	Yield
With resin D261 In acetonitrile Heating;	95%

: 95-82-9
2,5 dichloroaniline

: 536-74-3
phenylacetylene

: 2,5-dichloro-N-(1-phenylethylidene)aniline

Conditions

Conditions	Yield
With Ph3P-Au(phthalimide); C20H38N5(1+)H(1+)2BF4(1-) at 50℃; for 4h; Inert atmosphere;	95%
With C20H38N5(1+)H(1+)2BF4(1-); C16H8AuN2O4(1-)*C15H29N2(1+) at 50℃; for 4h; Inert atmosphere;	93%
With gallium(III) trichloride at 60℃; for 12h; regioselective reaction;

: 95-82-9
2,5 dichloroaniline

: 122835-14-7
5-bromo-2-prop-2-ynyloxy-benzaldehyde

: 121-45-9
phosphorous acid trimethyl ester

: dimethyl ((5-bromo-2-(prop-2-yn-1-yloxy)phenyl)((2,5-dichlorophenyl)amino)methyl)phosphonate

Conditions

Conditions	Yield
With triethylamine sulfate In neat (no solvent) at 20℃; for 0.5h; Green chemistry;	95%

...Expand

: 95-82-9
2,5 dichloroaniline

: Potassium; 4-amino-2,5-dichloro-benzenesulfonate

Conditions

Conditions	Yield
With sodium hydroxide; sulfuric acid In 1,2-dichloro-benzene at 35 - 40℃; Product distribution; var. alkaline agents;	94.1%
With potassium hydroxide; sulfuric acid In 1,2-dichloro-benzene at 35 - 40℃; Yield given;

: 50-00-0
formaldehyd

: 95-82-9
2,5 dichloroaniline

: 461677-71-4
1-benzyl-3-diazo-1,3-dihydro-2H-indol-2-one

: 1598427-65-6
1-benzyl-3-((2,5-dichlorophenyl)amino)-3-(hydroxymethyl)indolin-2-one

Conditions

Conditions	Yield
With dirhodium tetraacetate In water; ethyl acetate at 60℃; for 2h;	94%
With rhodium(II) acetate dimer In ethyl acetate at 60℃; for 2h;	94%

...Expand

: 95-82-9
2,5 dichloroaniline

: 201230-82-2
carbon monoxide

: 610-97-9
o-iodo-methyl-benzoic acid

: 1485-35-4
2-(2,5-dichlorophenyl)isoindoline-1,3-dione

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 100℃; under 760.051 Torr; for 1h; Schlenk technique;	94%

...Expand

: 95-82-9
2,5 dichloroaniline

: 5331-91-9
5-chloro-2-mercaptobenzothiazole

Conditions

Conditions	Yield
	93.5%

: 95-82-9
2,5 dichloroaniline

: 2,5-dichloroaniline-3-sulfonic acid

Conditions

Conditions	Yield
With sulfuric acid In 1,2-dichloro-benzene at 175 - 180℃; 3-5 h;	93.2%

: 95-82-9
2,5 dichloroaniline

: 106-51-4
p-benzoquinone

: 79756-69-7
2-(2',5'-dichlorophenyl)-1,4-benzoquinone

Conditions

Conditions	Yield
Stage #1: 2,5 dichloroaniline With hydrogenchloride; sodium nitrite In water at 0 - 5℃; for 1.5h; Stage #2: p-benzoquinone With sodium acetate In water	93%
Meerwein arylation;	70%

2,5-Dichloroaniline Consensus Reports

Reported in EPA TSCA Inventory.

2,5-Dichloroaniline Specification

The 2,5-Dichloroaniline, with the CAS registry number 95-82-9, is also known as Benzenamine, 2,5-dichloro-. It belongs to the product categories of Intermediates of Dyes and Pigments; Dyes and Pigments; Amines; C2 to C6; Nitrogen Compounds; Alpha Sort; Aromatics Pesticides & Metabolites; Chemical Class; D; DAlphabetic; DIA - DIC. Its EINECS registry number is 202-455-2. This chemical's molecular formula is C₆H₅Cl₂N and molecular weight is 162.02. What's more, its IUPAC name is the same with its product name. It should be stored in a cool, dry and well-ventilated place.

Physical properties about 2,5-Dichloroaniline are: (1)ACD/LogP: 2.715; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.72; (4)ACD/LogD (pH 7.4): 2.72; (5)ACD/BCF (pH 5.5): 68.10; (6)ACD/BCF (pH 7.4): 68.11; (7)ACD/KOC (pH 5.5): 714.10; (8)ACD/KOC (pH 7.4): 714.18; (9)#H bond acceptors: 1; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 1; (12)Polar Surface Area: 26.02 Å²; (13)Index of Refraction: 1.613; (14)Molar Refractivity: 40.279 cm³; (15)Molar Volume: 115.615 cm³; (16)Polarizability: 15.968×10^-24cm³; (17)Surface Tension: 48.33 dyne/cm; (18)Density: 1.401 g/cm³; (19)Flash Point: 100.361 °C; (20)Enthalpy of Vaporization: 48.829 kJ/mol; (21)Boiling Point: 250.999 °C at 760 mmHg; (22)Vapour Pressure: 0.021 mmHg at 25 °C.

Preparation of 2,5-Dichloroaniline: This chemical can be prepared by pyridine with (2,5-dichloro-phenyl)-hydrazine. This reaction needs reagent KO₂ at ambient temperature. The reaction time is 10 hours. The yield is 59 %.

Preparation of 2,5-Dichloroaniline

Uses of 2,5-Dichloroaniline: (1) It is used for synthetizing dye intermediates, it is also used in the manufacture of nitrogen fertilizer synergist. (2) It is used to produce other chemicals. For example, it can react with formic acid to get formic acid-(2,5-dichloro-anilide). This reaction temperature is 20 °C. The reaction time is 72 hours. The yield is 67 %.

2,5-Dichloroaniline can react with formic acid to get formic acid-(2,5-dichloro-anilide).

When you are dealing with this chemical, you should be very careful. This chemical may cause damage to health at low levels. It's very toxic by inhalation, in contact with skin and if swallowed. So you should keep it away from food, drink and animal feeding stuffs. After contacting with skin, you should wash immediately with plenty of abluent which is be specified by the manufacturer. In case of accident or if you feel unwell seek medical advice immediately. In addition, it may present an immediate or delayed danger to one or more components of the environment. This chemical very toxic to aquatic organisms and may cause long-term adverse effects in the aquatic environment. What's more, it may cause danger of cumulative effects. Therefore, this material and its container must be disposed of as hazardous waste. And you should refer to special instructions/safety data sheet before releasing it to the environment.

You can still convert the following datas into molecular structure:
(1) SMILES: Clc1ccc(Cl)c(N)c1
(2) InChI: InChI=1S/C6H5Cl2N/c7-4-1-2-5(8)6(9)3-4/h1-3H,9H2
(3) InChIKey: AVYGCQXNNJPXSS-UHFFFAOYSA-N

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LD50	oral	3750mg/kg (3750mg/kg)	PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 33(4), Pg. 8, 1968.
mouse	LD50	intraperitoneal	400mg/kg (400mg/kg)		Office of Toxic Substances Report. Vol. OTS,
mouse	LD50	intravenous	56mg/kg (56mg/kg)		U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#00202,
mouse	LD50	oral	1600mg/kg (1600mg/kg)		Office of Toxic Substances Report. Vol. OTS,
rabbit	LD50	oral	3750mg/kg (3750mg/kg)	LUNGS, THORAX, OR RESPIRATION: CYANOSIS BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)	Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 33(4), Pg. 8, 1968.
rat	LD50	intraperitoneal	400mg/kg (400mg/kg)		Office of Toxic Substances Report. Vol. OTS,
rat	LD50	oral	1600mg/kg (1600mg/kg)		Office of Toxic Substances Report. Vol. OTS,

Product Name

2,5-Dichloroaniline

Synthetic route

2,5-Dichloroaniline Consensus Reports

2,5-Dichloroaniline Specification

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