Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents, Our company h
Cas:610-97-9
Min.Order:1 Kilogram
FOB Price: $15.0 / 20.0
Type:Trading Company
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:610-97-9
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiryhigh quality Appearance:white powder Storage:Sealed, dry, microtherm , avoid light and smell Package:According to the demand of customer Application:Pharmaceutical intermediates Transportation:by air or by sea Port:shanghai
Product name: Methyl 2-iodobenzoate Alias: 2-iodobenzoic acid methyl ester CAS: 610-97-9 Molecular formula: C8H7IO2 Chemical structure: Methyl 2-iodobenzoate Appearance: colorless to light red liquid Content: 98% above Uses: me
Cas:610-97-9
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryAs a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch
Cas:610-97-9
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
Cas:610-97-9
Min.Order:0 Metric Ton
Negotiable
Type:Manufacturers
inquiry1 high purity 2 able to provide COA/HNMR/HPLC 3 High quality 4 low price 5 Best service Appearance:white crystalline powder Storage:-20°C Package:bag/bottle/drum Application:pharmaceutical intermediate Transportation:common transportation Por
Product description: Product name Methyl 2-iodobenzoate CAS number 610-97-9 Assay ≥99% Appearance Colorless to yellowish liquid Capacity 200mt/year Application Pharmaceutical
Cas:610-97-9
Min.Order:10 Gram
FOB Price: $12.0
Type:Lab/Research institutions
inquiryFactory supply Methyl 2-iodobenzoate Cas 610-97-9 with low price Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed addi
Cas:610-97-9
Min.Order:10 Kilogram
FOB Price: $10.0
Type:Trading Company
inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
Cas:610-97-9
Min.Order:1 Gram
FOB Price: $0.1
Type:Manufacturers
inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:610-97-9
Min.Order:5 Kiloliter
FOB Price: $1.2 / 5.0
Type:Manufacturers
inquiryOur company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O
Cas:610-97-9
Min.Order:1 Kilogram
FOB Price: $1000.0
Type:Lab/Research institutions
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:610-97-9
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiryProduct name: Methyl 2-iodobenzoate CAS No.: 610-97-9 Molecular formula C8H7IO2 Appearance: Colorless to slight red liquid Assay: 98.0% S
Cas:610-97-9
Min.Order:1 Kilogram
FOB Price: $1.0
Type:Other
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:610-97-9
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryOur company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese
Cas:610-97-9
Min.Order:1 Kilogram
FOB Price: $50.0 / 56.0
Type:Trading Company
inquiryMethyl 2-iodobenzoate CAS:610-97-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic inter
Cas:610-97-9
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:610-97-9
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryISO9001 1.Appearance: Colorless to redish 2.CAS No.610-97-9 3.MF: C8H7IO2 4.Assay: 98% min Appearance:colorless to redish liquid Storage:Store in dry and cool place with good seal Package:25kg/ Plastic drum Application:Pharmaceutical Intermedi
1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie
Cas:610-97-9
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia
Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
Cas:610-97-9
Min.Order:0 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryCompany Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments
Cas:610-97-9
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Why Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu
Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff
Cas:610-97-9
Min.Order:100 Gram
Negotiable
Type:Other
inquirySuperior quality, moderate price & quick delivery. Appearance:colourless or light yellow liquid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:25kg/drum, or as per your request. Application:Used as Pharm
Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,
Cas:610-97-9
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryConditions | Yield |
---|---|
With sulfuric acid Reflux; | 100% |
With sulfuric acid for 3h; Reflux; | 99% |
With sulfuric acid at 80℃; for 2.5h; Inert atmosphere; | 99% |
Conditions | Yield |
---|---|
With sulfuric acid Reflux; | 98% |
With sodium hydroxide | |
With oxalyl dichloride In dichloromethane for 0.5h; Inert atmosphere; | |
With triethylamine at 0 - 20℃; for 2h; | |
With triethylamine at 0 - 20℃; for 0.5h; | 0.42 g |
Conditions | Yield |
---|---|
With potassium carbonate In acetone | 98% |
With potassium carbonate In N,N-dimethyl-formamide at 20℃; | 96% |
Stage #1: 2-Iodobenzoic acid With caesium carbonate In N,N-dimethyl-formamide Stage #2: methyl iodide In N,N-dimethyl-formamide at 50℃; for 1h; | 95% |
2-(methoxycarbonyl)phenylzinc iodide
o-iodo-methyl-benzoic acid
Conditions | Yield |
---|---|
With N-chloro-succinimide In various solvent(s) at 20℃; for 0.166667h; Substitution; | 96% |
With N-chloro-succinimide In various solvent(s) at 20℃; for 0.166667h; | 48% |
trifluoroacetic acid-methyl ester
1-(2-iodophenyl)pentan-1-one
A
1,1,1-trifluoro-2-hexanone
B
o-iodo-methyl-benzoic acid
Conditions | Yield |
---|---|
Stage #1: trifluoroacetic acid-methyl ester With sodium hydride In tetrahydrofuran at 20℃; for 0.166667h; Inert atmosphere; Schlenk technique; Stage #2: 1-(2-iodophenyl)pentan-1-one In tetrahydrofuran at 0 - 20℃; for 3h; Inert atmosphere; Schlenk technique; Stage #3: With hydrogenchloride In tetrahydrofuran; water at 0℃; for 0.25h; Inert atmosphere; Schlenk technique; | A n/a B 96% |
Conditions | Yield |
---|---|
Stage #1: 2-carbomethoxyaniline With sulfuric acid; sodium nitrite In water at 0 - 7℃; Inert atmosphere; Stage #2: With sulfuric acid; sodium hydrogensulfite; potassium iodide In water at -5 - 80℃; for 1.58333h; Inert atmosphere; | 93% |
Stage #1: 2-carbomethoxyaniline With sulfuric acid; sodium nitrite Stage #2: With potassium iodide | |
Stage #1: 2-carbomethoxyaniline With toluene-4-sulfonic acid In acetonitrile at 20℃; for 0.166667h; Stage #2: With potassium iodide; sodium nitrite In water; acetonitrile at 0 - 20℃; |
2-iodo-N-(quinolin-8-yl)benzamide
o-iodo-methyl-benzoic acid
Conditions | Yield |
---|---|
With toluene-4-sulfonic acid In methanol at 110℃; for 36h; Sealed tube; | 93% |
Conditions | Yield |
---|---|
Stage #1: benzoic acid methyl ester With 2,2,6,6-tetramethyl-piperidine; n-butyllithium; cadmium(II) chloride-N,N,N',N'-tetramethylethylenediamine In tetrahydrofuran; hexane at 0 - 20℃; Inert atmosphere; Stage #2: With iodine In tetrahydrofuran; hexane Inert atmosphere; chemoselective reaction; | 89% |
Stage #1: benzoic acid methyl ester With (2,2,6,6-tetramethylpiperidido)2Ag(CN)Li2 In tetrahydrofuran at -40℃; for 2h; Stage #2: With iodine In tetrahydrofuran at 20℃; for 3h; Reagent/catalyst; chemoselective reaction; | 86% |
With N-iodo-succinimide; silver hexafluoroantimonate; trifluorormethanesulfonic acid; nickel diacetate In 1,2-dichloro-ethane at 80℃; for 12h; regioselective reaction; | 77% |
Stage #1: benzoic acid methyl ester With cadmium(II) chloride-N,N,N',N'-tetramethylethylenediamine; 2,2,6,6-tetramethylpiperidinyl-lithium In tetrahydrofuran; hexane at 20℃; for 2h; Inert atmosphere; Stage #2: With iodine In tetrahydrofuran; hexane Inert atmosphere; regioselective reaction; | 62% |
With 2,2,6,6-tetramethylpiperidinyl-lithium; iodine; di-tert-butylzinc 1.) THF, RT, 2.) THF, RT; Yield given; Multistep reaction; |
boron trifluoride dimethyl etherate
2-Iodobenzoic acid
o-iodo-methyl-benzoic acid
Conditions | Yield |
---|---|
at 120℃; for 4h; Reflux; | 89% |
2-Iodobenzoic acid
carbonic acid dimethyl ester
o-iodo-methyl-benzoic acid
Conditions | Yield |
---|---|
With potassium carbonate In dimethyl sulfoxide at 90℃; for 16h; Inert atmosphere; Green chemistry; | 88% |
Conditions | Yield |
---|---|
With iron(III) trifluoromethanesulfonate at 90℃; Schlenk technique; | 85% |
2-Iodobenzoic acid
methyl 1-imidazolecarboxylate
o-iodo-methyl-benzoic acid
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide at 80℃; for 24h; Inert atmosphere; | 84% |
Conditions | Yield |
---|---|
With 1,3-Diiodo-5,5-dimethyl-2,4-imidazolidinedione In 1,2-dichloro-ethane for 24h; Irradiation; Inert atmosphere; Reflux; | 80% |
With N-iodo-succinimide; [4,4’-bis(1,1-dimethylethyl)-2,2’-bipyridine-N1,N1‘]bis [3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-N]phenyl-C]iridium(III) hexafluorophosphate; iodine; caesium carbonate In 1,2-dichloro-ethane at 50℃; for 24h; Inert atmosphere; Irradiation; Sealed tube; | 65% |
2-iodo-N-methoxybenzamide
o-iodo-methyl-benzoic acid
Conditions | Yield |
---|---|
With N-Bromosuccinimide In toluene at 60℃; for 1h; | 76% |
methyl 2-(tosyldiazenyl)benzoate
o-iodo-methyl-benzoic acid
Conditions | Yield |
---|---|
With 18-crown-6 ether; potassium iodide In diethyl ether; acetonitrile for 4h; Ambient temperature; | 74% |
Conditions | Yield |
---|---|
With copper diacetate; acetic anhydride In N,N-dimethyl-formamide; acetonitrile at 130℃; for 1h; Sealed tube; | 57% |
methanol
carbon monoxide
1-(2-iodophenyl)diazonium tetrafluoroborate
o-iodo-methyl-benzoic acid
Conditions | Yield |
---|---|
With fluorescein free acid In acetonitrile at 20℃; under 60804.1 Torr; for 21h; Autoclave; Irradiation; | 50% |
Conditions | Yield |
---|---|
With hydrogenchloride; methanol | |
Multi-step reaction with 2 steps 1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 2 h / Inert atmosphere 2: oxalyl dichloride / dichloromethane / 0.5 h / Inert atmosphere View Scheme | |
Multi-step reaction with 2 steps 1: thionyl chloride; N,N-dimethyl-formamide / benzene / 2 h / 80 °C 2: triethylamine / 2 h / 0 - 20 °C View Scheme | |
Multi-step reaction with 2 steps 1: N,N-dimethyl-formamide; thionyl chloride / dichloromethane / 1 h 2: triethylamine / 0.5 h / 0 - 20 °C View Scheme |
Conditions | Yield |
---|---|
With (dissociation) In acetic acid at 15℃; Rate constant; |
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: hydrogenchloride; sodium nitrite / water / 0.5 h / 0 - 5 °C / Inert atmosphere 1.2: 1 h / 10 - 90 °C / Inert atmosphere 2.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 2 h / Inert atmosphere 3.1: oxalyl dichloride / dichloromethane / 0.5 h / Inert atmosphere View Scheme |
N-quinolin-8-yl-benzamide
o-iodo-methyl-benzoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: nickel dichloride; ammonium thiocyanate; potassium carbonate / N,N-dimethyl-formamide / 3 h / 120 °C 1.2: -10 °C 2.1: toluene-4-sulfonic acid / methanol / 36 h / 110 °C / Sealed tube View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: dmap; triethylamine / dichloromethane / 0.08 h / 0 °C / Inert atmosphere 1.2: 3 h / 0 - 20 °C / Inert atmosphere 2.1: nickel dichloride; ammonium thiocyanate; potassium carbonate / N,N-dimethyl-formamide / 3 h / 120 °C 2.2: -10 °C 3.1: toluene-4-sulfonic acid / methanol / 36 h / 110 °C / Sealed tube View Scheme |
Conditions | Yield |
---|---|
With copper(l) iodide; sodium iodide; zinc(II) iodide; N,N`-dimethylethylenediamine In 1,4-dioxane at 120℃; under 1500.15 Torr; for 24h; Reagent/catalyst; Finkelstein Reaction; Autoclave; Inert atmosphere; Schlenk technique; |
methyl 2-{[(4-methylphenyl)sulfonyl]oxy}benzoate
o-iodo-methyl-benzoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: (1,2-dimethoxyethane)dichloronickel(II); 1,4-bis(2,6-diisopropylphenyl)-2,3-dimethyl-1,4-diazabuta-1,3-diene / N,N-dimethyl-formamide; ethylene dibromide / 20 h / 20 °C / Schlenk technique 2: iodine / 0.17 h / 0 °C View Scheme |
o-iodo-methyl-benzoic acid
Conditions | Yield |
---|---|
With iodine at 0℃; for 0.166667h; | 501 mg |
o-iodo-methyl-benzoic acid
ethyl 4-(iodozincio)butanoate
ethyl 4-[(2-methoxycarbonyl)phenyl]butanoate
Conditions | Yield |
---|---|
dichlorobis(tri-O-tolylphosphine)palladium In N,N-dimethyl acetamide; benzene at 60℃; for 0.5h; | 100% |
o-iodo-methyl-benzoic acid
propargyl alcohol
methyl 2-(3-hydroxyprop-1-yn-1-yl)benzoate
Conditions | Yield |
---|---|
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In tetrahydrofuran at 40℃; for 0.5h; Sonogashira Cross-Coupling; Microwave irradiation; | 100% |
With triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide In acetonitrile for 3h; Inert atmosphere; Reflux; | 92% |
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; tetrabutylammomium bromide; triethylamine In benzene at 60℃; for 0.5h; | 90% |
o-iodo-methyl-benzoic acid
phenylacetylene
methyl 2-(phenylethynyl)benzoate
Conditions | Yield |
---|---|
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 20℃; Sonogashira Cross-Coupling; Inert atmosphere; | 100% |
With triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide at 55℃; Sonogashira coupling; | 99% |
With copper(l) iodide; trans-bis(triphenylphosphine)palladium dichloride; triethylamine In tetrahydrofuran at 55℃; Inert atmosphere; | 99% |
o-iodo-methyl-benzoic acid
trimethylsilylacetylene
methyl 2-(2-trimethylsilyl-1-ethynyl)benzoate
Conditions | Yield |
---|---|
With triethylamine; triphenylphosphine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide In tetrahydrofuran at 20℃; Sonogashira coupling reaction; | 100% |
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 20℃; for 15h; Sonogashira coupling; Inert atmosphere; | 100% |
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 20℃; for 24h; Inert atmosphere; | 100% |
o-iodo-methyl-benzoic acid
4-methoxyphenylboronic acid
methyl 4'-methoxybiphenyl-2-carboxylate
Conditions | Yield |
---|---|
With palladium diacetate; sodium carbonate In water; acetonitrile at 60℃; Suzuki-Miyaura Coupling; Inert atmosphere; | 100% |
With bis(triphenylphosphine)palladium(II) dichloride; sodium carbonate In tetrahydrofuran; water at 80℃; for 14h; Suzuki-Miyaura Coupling; Schlenk technique; Inert atmosphere; Sealed tube; | 95% |
With tetrakis(triphenylphosphine) palladium(0); sodium hydrogencarbonate In toluene for 18h; Heating; | 80% |
o-iodo-methyl-benzoic acid
2-(1-Hydroxypropyl)-1-ethynylbenzene
Methyl 2-<2-<2-(1-hydroxy-1-propyl)phenyl>ethynyl>benzoate
Conditions | Yield |
---|---|
With copper(l) iodide; bis(triphenylphosphine)palladium(II)-chloride; triethylamine for 16h; Heating; | 100% |
o-iodo-methyl-benzoic acid
2-Methoxyphenylboronic acid
2'-methoxy-biphenyl-2-carboxylic acid methyl ester
Conditions | Yield |
---|---|
With palladium diacetate; sodium carbonate; triphenylphosphine In water; N,N-dimethyl-formamide for 18h; Suzuki coupling; Ionic liquid; Reflux; Inert atmosphere; | 100% |
With potassium phosphate; SBA-Si-PEG-Pd(PPh3)n In water at 50℃; for 10h; Suzuki coupling; | 89% |
With di-tert-butylphosphine; (2,6-iPr2-C6H3OCO-N)-imidazolium-(N-CH2C6H4-2-Br) bromide; caesium carbonate; tris-(dibenzylideneacetone)dipalladium(0) In 1,4-dioxane at 150℃; for 48h; Suzuki-Miyaura coupling; | 86% |
With potassium carbonate In water at 80℃; for 10h; Suzuki-Miyaura Coupling; Green chemistry; | 26% |
carbon monoxide
o-iodo-methyl-benzoic acid
cyclohexylamine
N-cyclohexylphthalimide
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 100℃; under 760.051 Torr; for 1h; Schlenk technique; | 100% |
With 1,4-diaza-bicyclo[2.2.2]octane; palladium 10% on activated carbon In toluene at 120℃; under 4654.46 Torr; for 2h; Autoclave; | 93% |
With 1,3-bis-(diphenylphosphino)propane; palladium diacetate; caesium carbonate In toluene at 95℃; for 24h; | 92% |
carbon monoxide
o-iodo-methyl-benzoic acid
benzylamine
N-benzylphthalimide
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 100℃; under 760.051 Torr; for 1h; Schlenk technique; | 100% |
With 1,3-bis-(diphenylphosphino)propane; palladium diacetate; caesium carbonate In toluene at 95℃; for 24h; Reactivity; Reagent/catalyst; Concentration; Solvent; Temperature; Time; | 91% |
With triethylamine In toluene at 100℃; | 80% |
o-iodo-methyl-benzoic acid
dimethyl (1,1'-biphenyl)-2,3'-dicarboxylate
Conditions | Yield |
---|---|
With norborn-2-ene; palladium diacetate; caesium carbonate; triphenylphosphine In 1,2-dimethoxyethane at 90℃; for 1.5h; Sealed vial; | 100% |
With norbornene; palladium/alumina; potassium carbonate; benzyl alcohol at 105℃; for 72h; | 80% |
Conditions | Yield |
---|---|
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; N-ethyl-N,N-diisopropylamine at 20℃; Sonogashira coupling; | 100% |
Stage #1: Cyclopropylacetylene; o-iodo-methyl-benzoic acid With trans-bis(triphenylphosphine)palladium dichloride; triethylamine at 20℃; for 0.25h; Sonogashira Cross-Coupling; Inert atmosphere; Stage #2: With copper(l) iodide at 50℃; for 20h; Sonogashira Cross-Coupling; Inert atmosphere; | 100% |
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine | 99% |
o-iodo-methyl-benzoic acid
4-n-methylphenylacetylene
methyl 2-[(4-methylphenyl)ethynyl]benzoate
Conditions | Yield |
---|---|
Stage #1: o-iodo-methyl-benzoic acid; 4-n-methylphenylacetylene With trans-bis(triphenylphosphine)palladium dichloride; triethylamine at 20℃; for 0.25h; Sonogashira Cross-Coupling; Inert atmosphere; Stage #2: With copper(l) iodide at 50℃; for 1.5h; Sonogashira Cross-Coupling; Inert atmosphere; | 100% |
Stage #1: o-iodo-methyl-benzoic acid With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In tetrahydrofuran for 0.0833333h; Stage #2: 4-n-methylphenylacetylene In tetrahydrofuran for 16h; Reflux; | 99% |
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 20℃; Sonogashira coupling; Inert atmosphere; | 95% |
carbon monoxide
o-iodo-methyl-benzoic acid
N-butylamine
N-butylphthalimide
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 100℃; under 760.051 Torr; for 1h; Schlenk technique; | 100% |
With triethylamine In toluene at 100℃; | 79% |
4-n-chlorophenylacetylene
o-iodo-methyl-benzoic acid
2-(2-(4-chlorophenyl)ethynyl)benzoic acid methyl ester
Conditions | Yield |
---|---|
Stage #1: 4-n-chlorophenylacetylene; o-iodo-methyl-benzoic acid With trans-bis(triphenylphosphine)palladium dichloride; triethylamine at 20℃; for 0.25h; Sonogashira Cross-Coupling; Inert atmosphere; Stage #2: With copper(l) iodide at 50℃; for 2h; Sonogashira Cross-Coupling; Inert atmosphere; | 100% |
Stage #1: 4-n-chlorophenylacetylene; o-iodo-methyl-benzoic acid With trans-bis(triphenylphosphine)palladium dichloride; triethylamine at 20℃; for 0.166667h; Sonogashira Cross-Coupling; Inert atmosphere; Stage #2: With copper(l) iodide at 50℃; for 1h; Sonogashira Cross-Coupling; Inert atmosphere; | 99% |
Sonogashira Cross-Coupling; |
o-iodo-methyl-benzoic acid
trimethylsilylacetylene
2-ethynyl-benzoic acid methyl ester
Conditions | Yield |
---|---|
Stage #1: o-iodo-methyl-benzoic acid; trimethylsilylacetylene With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diisopropylamine In tetrahydrofuran at 20℃; for 2h; Inert atmosphere; Stage #2: With potassium carbonate In tetrahydrofuran; methanol at 20℃; for 12h; Inert atmosphere; | 100% |
o-iodo-methyl-benzoic acid
4-tert-butylphenylboronic acid
methyl 4′-(tert butyl)-[1,1′-biphenyl]-2-carboxylate
Conditions | Yield |
---|---|
With bis(triphenylphosphine)palladium(II) dichloride; sodium carbonate In tetrahydrofuran; water at 80℃; for 14h; Suzuki-Miyaura Coupling; Schlenk technique; Inert atmosphere; Sealed tube; | 100% |
With palladium diacetate; sodium carbonate In water; acetonitrile at 60℃; Suzuki-Miyaura Coupling; Inert atmosphere; | 90% |
With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate In tetrahydrofuran; water at 20 - 80℃; Suzuki Coupling; Schlenk technique; Inert atmosphere; | |
With potassium phosphate; palladium diacetate; triphenylphosphine In toluene at 80℃; Inert atmosphere; Schlenk technique; |
tetraacetyl thioglucose
o-iodo-methyl-benzoic acid
(2R,3R,4S,5R,6S)-2-(acetoxymethyl)-6-((2-(methoxycarbonyl)phenyl)thio)tetrahydro-2H-pyran-3,4,5-triyl triacetate
Conditions | Yield |
---|---|
With palladium diacetate; triethylamine; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene In 1,4-dioxane at 100℃; for 1h; Inert atmosphere; Schlenk technique; Sealed tube; | 100% |
3-ethynylthiophene
o-iodo-methyl-benzoic acid
Conditions | Yield |
---|---|
Stage #1: 3-ethynylthiophene; o-iodo-methyl-benzoic acid With trans-bis(triphenylphosphine)palladium dichloride; triethylamine at 20℃; for 0.25h; Sonogashira Cross-Coupling; Inert atmosphere; Stage #2: With copper(l) iodide at 50℃; for 3h; Sonogashira Cross-Coupling; Inert atmosphere; | 100% |
Stage #1: o-iodo-methyl-benzoic acid With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In N,N-dimethyl-formamide for 1h; Sonogashira Cross-Coupling; Inert atmosphere; Stage #2: 3-ethynylthiophene In N,N-dimethyl-formamide at 80 - 85℃; for 15h; Sonogashira Cross-Coupling; Inert atmosphere; | 82% |
With copper(l) iodide; trans-bis(triphenylphosphine)palladium dichloride; triethylamine In acetonitrile for 18h; Inert atmosphere; Schlenk technique; | 78% |
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In N,N-dimethyl-formamide at 85℃; for 16h; Sonogashira Cross-Coupling; Inert atmosphere; | |
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 20℃; Sonogashira Cross-Coupling; Inert atmosphere; |
o-iodo-methyl-benzoic acid
3-methoxyphenylboronic acid
3'-methoxy-[1,1'-biphenyl]-2-carboxylic acid
Conditions | Yield |
---|---|
Stage #1: o-iodo-methyl-benzoic acid; 3-methoxyphenylboronic acid With bis-triphenylphosphine-palladium(II) chloride; potassium phosphate In 1,2-dimethoxyethane; water at 180℃; for 0.25h; Microwave irradiation; Stage #2: With sodium hydroxide In methanol; water at 150℃; for 0.0833333h; Microwave irradiation; | 100% |
Conditions | Yield |
---|---|
Stage #1: 1-ethynyl-3-trifluoromethylbenzene; o-iodo-methyl-benzoic acid With trans-bis(triphenylphosphine)palladium dichloride; triethylamine at 20℃; for 0.25h; Sonogashira Cross-Coupling; Inert atmosphere; Stage #2: With copper(l) iodide at 50℃; for 1.5h; Sonogashira Cross-Coupling; Inert atmosphere; | 100% |
Stage #1: 1-ethynyl-3-trifluoromethylbenzene; o-iodo-methyl-benzoic acid With trans-bis(triphenylphosphine)palladium dichloride; triethylamine at 20℃; for 0.166667h; Sonogashira Cross-Coupling; Inert atmosphere; Stage #2: With copper(l) iodide at 50℃; for 1.5h; Sonogashira Cross-Coupling; Inert atmosphere; | 77% |
hexan-1-amine
carbon monoxide
o-iodo-methyl-benzoic acid
N-hexylphthalimide
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 100℃; under 760.051 Torr; for 1h; Schlenk technique; | 100% |
carbon monoxide
o-iodo-methyl-benzoic acid
4-Aminoacetophenone
2-(4-acetylphenyl)-1H-isoindole-1,3(2H)-dione
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 100℃; under 760.051 Torr; for 1h; Schlenk technique; | 100% |
propylamine
carbon monoxide
o-iodo-methyl-benzoic acid
N-propylphthalimide
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 100℃; under 760.051 Torr; for 1h; Schlenk technique; | 100% |
Conditions | Yield |
---|---|
Stage #1: cyclopentylacetylene; o-iodo-methyl-benzoic acid With trans-bis(triphenylphosphine)palladium dichloride; triethylamine at 20℃; for 0.25h; Sonogashira Cross-Coupling; Inert atmosphere; Stage #2: With copper(l) iodide at 50℃; for 20h; Sonogashira Cross-Coupling; Inert atmosphere; | 100% |
Conditions | Yield |
---|---|
With copper(l) iodide; N-ethyl-N,N-diisopropylamine; bis-triphenylphosphine-palladium(II) chloride In N,N-dimethyl-formamide at 20℃; for 24h; Arylation; | 99% |
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 24h; Condensation; | 99% |
With triethylamine; triphenylphosphine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide In tetrahydrofuran at 20℃; for 24h; Sonogashira coupling reaction; | 98% |
pent-1-yn-5-ol
o-iodo-methyl-benzoic acid
2-(5-hydroxypent-1-ynyl)benzoic acid methyl ester
Conditions | Yield |
---|---|
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 20℃; for 15h; Sonogashira Cross-Coupling; Inert atmosphere; | 99% |
With copper(l) iodide; triethylamine; trans-bis(triphenylphosphine)palladium(II) chloride at 25℃; for 12h; | 92% |
With piperidine; copper(l) iodide; tetrakis(triphenylphosphine) palladium(0) Sonogashira coupling reaction; | 86% |
With triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide at 55℃; Sonogashira coupling; | 85% |
Stage #1: o-iodo-methyl-benzoic acid With triethylamine for 0.0833333h; Inert atmosphere; Stage #2: pent-1-yn-5-ol With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide at 20℃; for 7h; Sonogashira coupling; Inert atmosphere; | 84% |
o-iodo-methyl-benzoic acid
hex-1-yne
2-(1-hexynyl)benzoic acid methyl ester
Conditions | Yield |
---|---|
Stage #1: o-iodo-methyl-benzoic acid With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diisopropylamine; triphenylphosphine at 20℃; for 1h; Inert atmosphere; Stage #2: hex-1-yne at 0 - 20℃; Inert atmosphere; | 99% |
Stage #1: hex-1-yne With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In N,N-dimethyl-formamide for 0.166667h; Inert atmosphere; Schlenk technique; Stage #2: o-iodo-methyl-benzoic acid In N,N-dimethyl-formamide at 25℃; for 2h; Inert atmosphere; Schlenk technique; | 98% |
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 18h; | 96% |
o-iodo-methyl-benzoic acid
N-Boc-indole-2-boronic acid
methyl 2-[1-(tert-butoxycarbonyl)-1H-indol-2-yl]benzoate
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In 1,2-dimethoxyethane; water for 12h; Suzuki-Miyaura coupling; Inert atmosphere; Reflux; | 99% |
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In 1,2-dimethoxyethane; water for 12h; Suzuki coupling; Reflux; | 97% |
2,2-dimethyl-3-butyne
o-iodo-methyl-benzoic acid
methyl 2-(3,3-dimethylbut-1-yn-1-yl)benzoate
Conditions | Yield |
---|---|
Stage #1: 3,3-Dimethylbut-1-yne; o-iodo-methyl-benzoic acid With trans-bis(triphenylphosphine)palladium dichloride; potassium carbonate In N,N-dimethyl-formamide at 20℃; for 0.25h; Sonogashira Cross-Coupling; Inert atmosphere; Stage #2: With copper(l) iodide In N,N-dimethyl-formamide at 50℃; for 16h; Sonogashira Cross-Coupling; Inert atmosphere; | 99% |
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); N-butylamine In diethyl ether Sonogashira coupling; | 98% |
Stage #1: 3,3-Dimethylbut-1-yne With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In N,N-dimethyl-formamide for 0.166667h; Inert atmosphere; Schlenk technique; Stage #2: o-iodo-methyl-benzoic acid In N,N-dimethyl-formamide at 25℃; for 2h; Inert atmosphere; Schlenk technique; | 91% |
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View