2,5-Thiophenedicarboxylic acid supplier

Name
2,5-Thiophenedicarboxylic acid
EINECS 224-284-2
CAS No. 4282-31-9
Article Data42
CAS DataBase
Density 1.655 g/cm³
Solubility Very soluble in water.
Melting Point >300 °C(lit.)
Formula C₆H₄O₄S
Boiling Point 444.6 °C at 760 mmHg
Molecular Weight 172.161
Flash Point 222.7 °C
Transport Information
Appearance white to light yellow crystal powder
Safety 26-36-37/39
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms 2,5-Dicarboxythiophene;NSC 81789;Thiophene-2,5-dicarboxylic acid;
PSA 102.84000
LogP 1.14450

Synthetic route

: 18853-40-2
2,5-thiophenedicarbonitrile

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

Conditions

Conditions	Yield
With hydrogenchloride for 6h; Heating;	79%

: 124-04-9
Adipic acid

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

Conditions

Conditions	Yield
Stage #1: Adipic acid With dmap; thionyl chloride at 78 - 81℃; for 3.5h; Large scale; Stage #2: With sodium hydroxide In water at 70 - 72℃; for 2h; pH=9.3 - 10; Reagent/catalyst; Temperature; pH-value; Large scale;	75.58%

: 61755-85-9
2,5‐diethyl thiophene‐2,5‐dicarboxylate

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

Conditions

Conditions	Yield
With potassium hydroxide In ethanol for 2h; Heating;	70%
With potassium hydroxide

: 625-88-7
2,5-diiodothiophene

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

Conditions

Conditions	Yield
With n-butyllithium; carbon dioxide In tetrahydrofuran; water	60%
With diethyl ether; phenyllithium Behandeln des Reaktionsgemisches mit festem Kohlendioxid;

: 67-56-1
methanol

: 3141-27-3
2,5-dibromothiophen

: 201230-82-2
carbon monoxide

A: 4282-31-9
Thiophene-2,5-dicarboxylic acid

B: 4282-34-2
Dimethyl thiophene-2,5-dicarboxylate

Conditions

Conditions	Yield
With tert-Amyl alcohol; sodium hydride; cobalt(II) acetate In tetrahydrofuran at 40℃; under 760 Torr; for 54h; Irradiation;	A 17% B 55%

...Expand

: 3141-27-3
2,5-dibromothiophen

: 201230-82-2
carbon monoxide

A: 4282-31-9
Thiophene-2,5-dicarboxylic acid

B: 4282-34-2
Dimethyl thiophene-2,5-dicarboxylate

Conditions

Conditions	Yield
With methanol; tert-Amyl alcohol; sodium hydride; cobalt(II) acetate In tetrahydrofuran at 40℃; under 760 Torr; for 54h; Irradiation;	A 17% B 55%

...Expand

: 3141-27-3
2,5-dibromothiophen

: 124-38-9
carbon dioxide

A: 7311-63-9
5-bromothiophene-2-carboxylic acid

B: 4282-31-9
Thiophene-2,5-dicarboxylic acid

Conditions

Conditions	Yield
Stage #1: 2,5-dibromothiophen; carbon dioxide With tert.-butyl lithium In pentane at -70℃; Inert atmosphere; Stage #2: With sulfuric acid; water In pentane at 20℃; Inert atmosphere;	A 34% B 5%

...Expand

: 188290-36-0
thiophene

: 1822-71-5
n-pentylsodium

: 14593-46-5
sodium tert-pentoxide

: 15719-64-9, 15719-76-3, 97762-63-5
methylammonium carbonate

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

Conditions

Conditions	Yield
aufeinanderfolgender Umsetzung;

...Expand

: 188290-36-0
thiophene

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

Conditions

Conditions	Yield
With n-heptane; n-pentylsodium; sodium tert-pentoxide anschliessend Behandeln mit festem Kohlendioxid;

: 638-02-8
2,5-DIMETHYLTHIOPHENE

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

Conditions

Conditions	Yield
With alkaline permanganate solution

: 13679-74-8
2-Acetyl-5-methylthiophen

A: 1918-79-2
2-methylthiophene-5-carboxylic acid

B: 4282-31-9
Thiophene-2,5-dicarboxylic acid

Conditions

Conditions	Yield
With potassium hydroxide; potassium permanganate Behandeln des Reaktionsprodukts mit wss. Wasserstoffperoxid;

: 13679-74-8
2-Acetyl-5-methylthiophen

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

Conditions

Conditions	Yield
With alkaline permanganate solution
With sodium hydroxide; potassium permanganate Oxidation;

: 28569-48-4
2,5-bis-chloromethyl-thiophene

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

Conditions

Conditions	Yield
With potassium hydroxide; potassium permanganate
With potassium permanganate; acetone

: 131543-46-9
Glyoxal

: 925-47-3
diethyl thioglycolate

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

Conditions

Conditions	Yield
With sodium ethanolate Abdampfen der mit Wasser versetzten Mischung und Ansaeuern mit Salzsaeure;

: 18761-46-1
1-(5-ethyl-thiophen-2-yl)-ethanone

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

Conditions

Conditions	Yield
With alkaline permanganate solution

: 188290-36-0
thiophene

: 124-38-9
carbon dioxide

A: 527-72-0
2-thiophenylcarboxylic acid

B: 4282-31-9
Thiophene-2,5-dicarboxylic acid

Conditions

Conditions	Yield
With n-butyllithium 1.) methylcyclohexane, THF, from 0 deg C to 25 deg C, 20 h, 2.) methylcyclohexane, THF, ether; Yield given. Multistep reaction. Yields of byproduct given;

...Expand

: 3141-27-3
2,5-dibromothiophen

: 124-38-9
carbon dioxide

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

Conditions

Conditions	Yield
With n-butyllithium 1. THF/-50 - -55 deg C; Yield given. Multistep reaction;
Stage #1: 2,5-dibromothiophen With iodine; magnesium In tetrahydrofuran; 1,4-dioxane at 60℃; for 4h; Inert atmosphere; Stage #2: carbon dioxide In tetrahydrofuran; 1,4-dioxane Solvent; Temperature;

: 527-72-0
2-thiophenylcarboxylic acid

: 124-38-9
carbon dioxide

A: 4282-31-9
Thiophene-2,5-dicarboxylic acid

B: 1451-95-2
thiophene-2,3-dicarboxylic acid

Conditions

Conditions	Yield
With n-butyllithium 1.) THF/hexane, -78 deg C, 30 min, 2.) THF/hexane, -78 -> -10 deg C; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;

...Expand

5-chloromethyl-thiophene-2-carboxylic acid ethyl ester: 5-chloromethyl-thiophene-2-carboxylic acid ethyl ester

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

Conditions

Conditions	Yield
With nitric acid

5-ethyl-thiophene-carboxylic acid-(2): 5-ethyl-thiophene-carboxylic acid-(2)

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

Conditions

Conditions	Yield
With alkaline permanganate solution

5-methyl-thiophene-carboxylic acid-(2): 5-methyl-thiophene-carboxylic acid-(2)

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

Conditions

Conditions	Yield
With alkaline permanganate solution

potassium salt of/the/ thiophene-disulfonic acid-(2.4): potassium salt of/the/ thiophene-disulfonic acid-(2.4)

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

Conditions

Conditions	Yield
With potassium cyanide Verseifen durch Kochen mit alkoh. Kali;

potassium-salt of/the/ thiophene-2-carboxylic acid: potassium-salt of/the/ thiophene-2-carboxylic acid

A: 188290-36-0
thiophene

B: 4282-31-9
Thiophene-2,5-dicarboxylic acid

Conditions

Conditions	Yield
With cadmium catalyst unter Kohlendioxid;

: 872-55-9
2-ethylthiophene

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: petroleum ether; aluminium chloride 2: alkaline permanganate solution View Scheme

: 4282-34-2
Dimethyl thiophene-2,5-dicarboxylate

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

Conditions

Conditions	Yield
With sulfuric acid In water at 60℃; for 2h; Large scale;	1679 g

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

: 64-17-5
ethanol

: 61755-85-9
2,5‐diethyl thiophene‐2,5‐dicarboxylate

Conditions

Conditions	Yield
With sulfuric acid Reflux;	100%
With sulfuric acid for 120h; Reflux;	90%
With graphene oxide at 100℃; for 24h;	67%
With sulfuric acid at 85℃; for 72h; Inert atmosphere;	3.2 g
for 6h; Reflux;

: 67-56-1
methanol

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

: 4282-34-2
Dimethyl thiophene-2,5-dicarboxylate

Conditions

Conditions	Yield
With thionyl chloride at 0 - 20℃; for 3h; Heating / reflux;	99.9%
With thionyl chloride Reflux;	99%
With thionyl chloride Reflux;	99%

: 280-57-9
1,4-diaza-bicyclo[2.2.2]octane

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

: zinc(II) nitrate hexahydrate

: 584-03-2
1,2-dihydroxybutane

: [Zn12(thiophene-2,5-dicarboxylic acid)6(1,2-butanediol)6(1,4-diaza-bicyclo[2.2.2]octane)3]

Conditions

Conditions	Yield
Stage #1: 1,4-diaza-bicyclo[2.2.2]octane; Thiophene-2,5-dicarboxylic acid; zinc(II) nitrate hexahydrate In N,N-dimethyl-formamide for 1h; Stage #2: 1,2-dihydroxybutane In N,N-dimethyl-formamide at 130℃; for 48h; Sealed tube;	99%

...Expand

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

: 1199-46-8
2-amino-4-tert-butylphenol

: 7128-64-5
Uvitex OB

Conditions

Conditions	Yield
With boric acid In toluene at 170 - 240℃; Solvent; Temperature; Inert atmosphere;	98.7%

: 280-57-9
1,4-diaza-bicyclo[2.2.2]octane

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

: zinc(II) nitrate hexahydrate

: 107-21-1
ethylene glycol

: [Zn12(thiophene-2,5-dicarboxylic acid)6(ethylene glycol)6(1,4-diaza-bicyclo[2.2.2]octane)3]

Conditions

Conditions	Yield
Stage #1: 1,4-diaza-bicyclo[2.2.2]octane; Thiophene-2,5-dicarboxylic acid; zinc(II) nitrate hexahydrate In N,N-dimethyl-formamide for 1h; Stage #2: ethylene glycol In N,N-dimethyl-formamide at 130℃; for 48h; Sealed tube;	98%

...Expand

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

: 91-76-9
benzoguanamine

: C15H11N5O3S

Conditions

Conditions	Yield
In ethanol for 2h; Reflux;	97.9%

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

: 5856-62-2
(S)-2-aminobutan-1-ol

: (-)-2,5-bis[4'-(S)-ethyloxazolin-2'-yl]thiophene

Conditions

Conditions	Yield
In toluene for 24h; Reflux; water segregator;	96%

: 280-57-9
1,4-diaza-bicyclo[2.2.2]octane

: 57-55-6
propylene glycol

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

: zinc(II) nitrate hexahydrate

: [Zn12(thiophene-2,5-dicarboxylic acid)6(1,2-propanediol)6(1,4-diaza-bicyclo[2.2.2]octane)3]

Conditions

Conditions	Yield
Stage #1: 1,4-diaza-bicyclo[2.2.2]octane; Thiophene-2,5-dicarboxylic acid; zinc(II) nitrate hexahydrate In N,N-dimethyl-formamide for 1h; Stage #2: propylene glycol In N,N-dimethyl-formamide at 130℃; for 48h; Sealed tube;	96%

...Expand

: 280-57-9
1,4-diaza-bicyclo[2.2.2]octane

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

: zinc(II) nitrate hexahydrate

: 5343-92-0
1,2-pentanediol

: [Zn12(thiophene-2,5-dicarboxylic acid)6(1,2-pentanediol)6(1,4-diaza-bicyclo[2.2.2]octane)3]

Conditions

Conditions	Yield
Stage #1: 1,4-diaza-bicyclo[2.2.2]octane; Thiophene-2,5-dicarboxylic acid; zinc(II) nitrate hexahydrate In N,N-dimethyl-formamide for 1h; Stage #2: 1,2-pentanediol In N,N-dimethyl-formamide at 130℃; for 48h; Sealed tube;	96%

...Expand

: 190773-57-0
N,N’,N’’,N’’’-tetrakis(2-pyridylmethyl)-1,6-diaminohexane

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

: 6147-53-1
cobalt(II) diacetate tetrahydrate

: poly{[Co2(thiophene-2,5-dicarboxylato)2(N,N’,N’’,N’’’-tetrakis(2-pyridylmethyl)-1,6-diaminohexane)]·H2O}

Conditions

Conditions	Yield
Stage #1: N,N’,N’’,N’’’-tetrakis(2-pyridylmethyl)-1,6-diaminohexane; cobalt(II) diacetate tetrahydrate In methanol at 20℃; Stage #2: Thiophene-2,5-dicarboxylic acid In methanol at 20℃;	96%

...Expand

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

: tungsten 2,2-dimethylpropionate

: [((pivalate)3W2)2(2,5-thienyldicarboxylate)]

Conditions

Conditions	Yield
In toluene C4H2S(COOH)2 added to soln. of W2((CH3)3CCOO)4 in toluene; soln. stirredfor 7-10 d at rt; precipitate filtered off; detd. by elem. anal.;	95%
In toluene under Ar atm. to soln. (W2(O2C(t)Bu)4) in toluene 2,5-Th(COOH)2 was added and stirred at room temp. for 5-10 days; ppt. was filtered, washed with toluene and hexane, and dried in vacuo; elem. anal.;	95%

: 110-86-1
pyridine

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

: bismuth (III) nitrate pentahydrate

: 2C6H2O4S(2-)*2.5H2O*Bi(3+)*C5H5N*H(1+)

Conditions

Conditions	Yield
With acetic acid In ethanol at 20℃; for 120 - 168h; pH=4 - 5;	94%

...Expand

: 280-57-9
1,4-diaza-bicyclo[2.2.2]octane

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

: zinc(II) nitrate hexahydrate

: 56-81-5
glycerol

: [Zn12(thiophene-2,5-dicarboxylic acid)6(glycerol)6(1,4-diaza-bicyclo[2.2.2]octane)3]

Conditions

Conditions	Yield
Stage #1: 1,4-diaza-bicyclo[2.2.2]octane; Thiophene-2,5-dicarboxylic acid; zinc(II) nitrate hexahydrate In N,N-dimethyl-formamide for 1h; Stage #2: glycerol In N,N-dimethyl-formamide at 130℃; for 48h; Sealed tube;	94%

...Expand

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

: 95-84-1
3-amino-4-hydroxytoluene

: 3723-19-1
5,5'-dimethyl-2,2'-thiophene-2,5-diyl-bis-benzooxazole

Conditions

Conditions	Yield
With boric acid; tin(ll) chloride In 1,2-dichloro-benzene at 220℃; for 24h; Inert atmosphere; Dean-Stark;	94%

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

: 3182-95-4
L-Phenylalaninol

: (+)-2,5-bis[4'-(S)-benzyloxazolin-2'-yl]thiophene

Conditions

Conditions	Yield
In toluene for 24h; Reflux; water segregator;	93%

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

: 20989-17-7
(2S)-2-phenylglycinol

: 1259933-47-5
(+)-2,5-bis[4'-(S)-phenyloxazolin-2'-yl]thiophene

Conditions

Conditions	Yield
In toluene for 24h; Reflux; water segregator;	93%

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

: 1117-97-1
N,0-dimethylhydroxylamine

: 821797-87-9
N2,N5-dimethoxy-N2,N5-dimethylthiophene-2,5-dicarboxamide

Conditions

Conditions	Yield
Stage #1: Thiophene-2,5-dicarboxylic acid; N,0-dimethylhydroxylamine In toluene at 0℃; for 0.166667h; Stage #2: With phosphorus trichloride In toluene at 20 - 60℃; for 0.5h;	92%

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

: manganese(II) chloride tetrahydrate

: 1349082-74-1
2-(5-{6-[5-(pyrazin-2-yl)-1H-1,2,4-triazol-3-yl]-pyridin-2-yl}-1H-1,2,4-triazol-3-yl)pyrazine

: 7732-18-5
water

: {[Mn2(ptptp)(Hbtc)(H2O)2]·2H2O}n

Conditions

Conditions	Yield
With 3-ethyl-1-methyl-1H-imidazol-3-ium bromide In acetonitrile at 160℃; for 72h; Reagent/catalyst; Autoclave;	92%

...Expand

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

: 2026-48-4
(S)-valinol

: (-)-2,5-bis[4'-(S)-isopropyloxazolin-2'-yl]thiophene

Conditions

Conditions	Yield
In toluene for 24h; Reflux; water segregator;	91%

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

: dimolybdenum tetrapivalate

: [((pivalate)3Mo2)2(2,5-thienyldicarboxylate)]

Conditions

Conditions	Yield
In toluene C4H2S(COOH)2 added to soln. of Mo2((CH3)3CCOO)4 in toluene; soln. stirred for 7-10 d at rt; precipitate filtered off; detd. by elem. anal., MALDI;	90%
In toluene under Ar atm. to soln. (Mo2(O2C(t)Bu)4) in toluene 2,5-Th(COOH)2 was added and stirred at room temp. for 5-10 days; ppt. was filtered; elem. anal.;	90%

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

: manganese(II) chloride tetrahydrate

: 7732-18-5
water

: Mn2(thiophene-2,5-dicarboxylate)2(H2O)3

Conditions

Conditions	Yield
With NH3H2O In water High Pressure; mixt. of MnCl24H2O, thiohene-2,5-dicarboxylic acid, H2O adjusted to pH 7.4 by aq. soln. of NH3*H2O, placed in autoclave, heated at 110°Cfor 3 d, slow cooled to room temp.; ppt. filtered, washed with H2O; elem. anal.;	90%

...Expand

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

: cobalt(II) chloride hexahydrate

: 7732-18-5
water

: Co2(thiophene-2,5-dicarboxylate)2(H2O)3

Conditions

Conditions	Yield
With NH3H2O In water High Pressure; mixt. of CoCl26H2O, thiohene-2,5-dicarboxylic acid, H2O adjusted to pH 7.4 by aq. soln. of NH3*H2O, placed in autoclave, heated at 110°Cfor 3 d, slow cooled to room temp.; ppt. filtered, washed with H2O; elem. anal.;	90%

...Expand

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

: zinc(II) nitrate hexahydrate

: 2,5-bis(4-(pyridine-4-yl)phenyl)thiazolo[5,4-d]thiazole

: 68-12-2, 33513-42-7
N,N-dimethyl-formamide

: [Zn2(2,5-bis(4-(pyridine-4-yl)phenyl)thiazolo[5,4-d]thiazole)2(2,5-thiophene dicarboxylate)2]n*2DMF

Conditions

Conditions	Yield
at 120℃; for 72h;	90%

...Expand

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

: aluminum(III) sulphate octadecahydrate

: 7732-18-5
water

: [Al(μ-OH)(2,5-thiophenedicarboxylate)]

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 135℃; for 24h;	90%

...Expand

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

: 6147-53-1
cobalt(II) diacetate tetrahydrate

: 263713-26-4
N,N’-(1,4-phenylenebis(methylene))bis(1-(pyridin-2-yl)-N-(pyridin-2-ylmethyl)methanamine)

: poly{[Co2(thiophene-2,5-dicarboxylato)2(N,N’-(1,4-phenylenebis(methylene))bis(1-(pyridin-2-yl)-N-(pyridin-2-ylmethyl)methanamine))]·6H2O}

Conditions

Conditions	Yield
Stage #1: cobalt(II) diacetate tetrahydrate; N,N’-(1,4-phenylenebis(methylene))bis(1-(pyridin-2-yl)-N-(pyridin-2-ylmethyl)methanamine) In methanol at 20℃; Stage #2: Thiophene-2,5-dicarboxylic acid In methanol at 20℃;	90%

...Expand

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

: 95-55-6
2-amino-phenol

: 2866-43-5
2,2'-thiophene-2,5-diylbis(benzoxazole)

Conditions

Conditions	Yield
With boric acid; tin(ll) chloride In 1,2-dichloro-benzene at 220℃; for 24h; Inert atmosphere; Dean-Stark;	89.23%
Stage #1: Thiophene-2,5-dicarboxylic acid; 2-amino-phenol at 150℃; for 2h; Inert atmosphere; Stage #2: With ammonia In water at 20℃; pH=~ 10 - 11; Cooling with cold water;	5.5%
With boric acid In 1-methyl-pyrrolidin-2-one; toluene at 20 - 185℃; for 13h;

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

: 112245-13-3
(S)-tert-leucinol

: (+)-2,5-bis[4'-(S)-tert-butyloxazolin-2'-yl]thiophene

Conditions

Conditions	Yield
In toluene for 24h; Reflux; water segregator;	89%

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

: manganese(II) chloride tetrahydrate

: 563-83-7
ISOPROPYLAMIDE

A: Mn2(2,5-thiophenedicarboxylate)2(N,N-dimethylacetamide)2

B: Mn2(2,5-thiophenedicarboxylate)2(acetate)*(dimethylammonium)

Conditions

Conditions	Yield
at 120℃; for 120h; High pressure;	A 89% B n/a

...Expand

: 64-18-6
formic acid

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

: 10026-11-6
zirconium(IV) chloride

: 68-12-2, 33513-42-7
N,N-dimethyl-formamide

: [Zr6O6(OH)2(2,5-thiophenedicarboxylate)4(formate)2(N,Ndimethylformamide)*(H2O)5]

Conditions

Conditions	Yield
In 1-methyl-pyrrolidin-2-one at 120℃; for 48h; Sonication;	89%

...Expand

: 64-18-6
formic acid

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

: 10026-11-6
zirconium(IV) chloride

: 68-12-2, 33513-42-7
N,N-dimethyl-formamide

: Zr6O6(OH)2(2,5-thiophenedicarboxylate)4(HCOO)2(DMF)2

Conditions

Conditions	Yield
In 1-methyl-pyrrolidin-2-one at 80℃; for 48h;	89%

...Expand

2,5-Thiophenedicarboxylic acid Chemical Properties

Empirical Formula: C₆H₄O₄S
Molecular Weight: 172.1586
Index of Refraction: 1.662
Molar Refractivity: 38.49 cm³
Molar Volume: 103.9 cm³
Surface Tension: 83.9 dyne/cm
Density: 1.655 g/cm³
Flash Point: 222.7 °C
Enthalpy of Vaporization: 74.03 kJ/mol
Boiling Point: 444.6 °C at 760 mmHg
Vapour Pressure: 1.1E-08 mmHg at 25 °C
Melting point: >300 °C(lit.)
Appearance: White to light yellow crystal powder
Structure of 2,5-Thiophenedicarboxylic acid (CAS NO.4282-31-9):

Product Category of 2,5-Thiophenedicarboxylic acid (CAS NO.4282-31-9): Thiophenes;Thiophens;Functional Materials;Reagents for Conducting Polymer Research;Thiophene Derivatives (for Conduting Polymer Research);Thiophen;Heterocyclic Building Blocks

2,5-Thiophenedicarboxylic acid Safety Profile

Hazard Codes: Irritant Xi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36-37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
S37/39:Wear suitable gloves and eye/face protection.

2,5-Thiophenedicarboxylic acid Specification

2,5-Thiophenedicarboxylic acid , its cas register number is 4282-31-9. It also can be called Thiophene-2,5-dicarboxylic acid ; and NSC 81789 . It is hazardous, so the first aid measures and others should be known. Such as: When on the skin: first, should flush skin with plenty of water immediately for at least 15 minutes while removing contaminated clothing. Secondly, get medical aid. Or in the eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Then get medical aid soon. While, it's inhaled: Remove from exposure and move to fresh air immediately. Give artificial respiration while not breathing. When breathing is difficult, give oxygen. And as soon as to get medical aid. Then you have the ingesting of the product: Wash mouth out with water, and get medical aid immediately. Notes to physician: Treat supportively and symptomatically.
In addition, 2,5-Thiophenedicarboxylic acid (CAS NO.4282-31-9) is not compatible with strong oxidizing agents, and you must not take it with incompatible materials. And also prevent it to broken down into hazardous decomposition products: Carbon monoxide, carbon dioxide, sulfur oxides (SO_x), including sulfur oxide and sulfur dioxide.

Product Name

2,5-Thiophenedicarboxylic acid

Synthetic route

2,5-Thiophenedicarboxylic acid Chemical Properties

2,5-Thiophenedicarboxylic acid Safety Profile

2,5-Thiophenedicarboxylic acid Specification

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