2-Amino-3-hydroxyphenazine supplier

Name
3-AMINO-PHENAZIN-2-OL
EINECS
CAS No. 4569-77-1
Article Data19
CAS DataBase
Density 1.46g/cm³
Solubility
Melting Point >300℃
Formula C12H9 N3 O
Boiling Point 381.6°Cat760mmHg
Molecular Weight 211.223
Flash Point 184.6°C
Transport Information
Appearance
Safety Mutation data reported. When heated to decomposition it emits toxic vapors of NO_x.
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms 2-Amino-3-hydroxyphenazine;2-Hydroxy-3-aminophenazine; 3-Amino-2-hydroxyphenazine; 3-Amino-2-phenazinol;NSC 52575
PSA 72.03000
LogP 2.65200

Synthetic route

: 95-54-5
1,2-diamino-benzene

A: 655-86-7
2,3-diaminephenazine

B: 4569-77-1
2-amino-3-hydroxy-phenazine

Conditions

Conditions	Yield
With hydrogenchloride; iron(III) chloride at 20℃;	A 78% B n/a
With hydrogenchloride; iron(III) chloride
With hydrogenchloride; iron(III) chloride at 20℃; under 760 Torr; Title compound not separated from byproducts;

: 775347-31-4
2-amino-5-hydroxy-[1,4]benzoquinone

: 39145-59-0
o-phenylenediamine hydrochloride

: 4569-77-1
2-amino-3-hydroxy-phenazine

Conditions

Conditions	Yield
With ethanol

: 95-54-5
1,2-diamino-benzene

: 4569-77-1
2-amino-3-hydroxy-phenazine

Conditions

Conditions	Yield
With hydrogenchloride; iron(III) chloride In water at 60 - 70℃;

: 4569-77-1
2-amino-3-hydroxy-phenazine

: 95-54-5
1,2-diamino-benzene

: 111076-33-6
5,14-dihydro-5,7,12,14-tetraazapentacene

Conditions

Conditions	Yield
With hydrogenchloride; sodium chloride In water at 320℃; for 0.0833333h;	100%

: 4569-77-1
2-amino-3-hydroxy-phenazine

: C12H8N3O(1-)*Na(1+)

Conditions

Conditions	Yield
With sodium hydroxide In ethanol at 20℃;	98%

: 4569-77-1
2-amino-3-hydroxy-phenazine

: 3171-45-7
4,5-dimethyl-1,2-phenylenediamine

: 8,9-dimethyl-5,14-dihydro-5,7,12,14-tetraazapentacene

Conditions

Conditions	Yield
With hydrogenchloride; sodium chloride In water at 320℃; for 0.0833333h;	95%

: 4569-77-1
2-amino-3-hydroxy-phenazine

: 446-52-6
2-Fluorobenzaldehyde

: 105-56-6
ethyl 2-cyanoacetate

: ethyl 3,5-diamino-1-(2-fluorophenyl)-1H-pyrano[3,2-a]phenazine-2-carboxylate

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In ethanol Reflux;	93%

...Expand

: 4569-77-1
2-amino-3-hydroxy-phenazine

: 89-98-5
2-chloro-benzaldehyde

: 109-77-3
malononitrile

: 3,5-diamino-1-(2-chlorophenyl)-1H-pyrano[3,2-a]phenazine-2-carbonitrile

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In ethanol Reflux;	91%

...Expand

: 3132-99-8
m-bromobenzoic aldehyde

: 4569-77-1
2-amino-3-hydroxy-phenazine

: 105-56-6
ethyl 2-cyanoacetate

: ethyl 3,5-diamino-1-(3-bromophenyl)-1H-pyrano[3,2-a]phenazine-2-carboxylate

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In ethanol Reflux;	90%

...Expand

: 4569-77-1
2-amino-3-hydroxy-phenazine

: 100-52-7
benzaldehyde

: 109-77-3
malononitrile

: C22H15N5O

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In ethanol Reflux; Inert atmosphere;	89%

...Expand

: 4569-77-1
2-amino-3-hydroxy-phenazine

: 31558-40-4
4-bromo-3,5-dimethoxybenzaldehyde

: 105-56-6
ethyl 2-cyanoacetate

: ethyl 3,5-diamino-1-(4-bromo-3,5-dimethoxyphenyl)-1H-pyrano[3,2-a]phenazine-2-carboxylate

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In ethanol Reflux;	89%

...Expand

: 4569-77-1
2-amino-3-hydroxy-phenazine

: 83-38-5
2,6-dichlorobenzaldehyde

: 109-77-3
malononitrile

: 3,5-diamino-1-(2,6-dichlorophenyl)-1H-pyrano[3,2-a]phenazine-2-carbonitrile

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In ethanol Reflux;	86%

...Expand

: 4569-77-1
2-amino-3-hydroxy-phenazine

: 6948-30-7
5-bromoveratralaldehyde

: 109-77-3
malononitrile

: 3,5-diamino-1-(3-bromo-4,5-dimethoxyphenyl)-1H-pyrano[3,2-a]phenazine-2-carbonitrile

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In ethanol Reflux;	86%

...Expand

: 4569-77-1
2-amino-3-hydroxy-phenazine

: 105-56-6
ethyl 2-cyanoacetate

: 6630-33-7
ortho-bromobenzaldehyde

: ethyl 3,5-diamino-1-(2-bromophenyl)-1H-pyrano[3,2-a]phenazine-2-carboxylate

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In ethanol Reflux;	86%

...Expand

: 4569-77-1
2-amino-3-hydroxy-phenazine

: 25016-01-7
5-bromo-2-methoxybenzaldehyde

: 105-56-6
ethyl 2-cyanoacetate

: ethyl 3,5-diamino-1-(5-bromo-2-methoxyphenyl)-1H-pyrano[3,2-a]phenazine-2-carboxylate

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In ethanol Reflux;	86%

...Expand

: 75-15-0
carbon disulfide

: 4569-77-1
2-amino-3-hydroxy-phenazine

: 92978-52-4
2-mercapto-oxazole[4,5-b]phenazine

Conditions

Conditions	Yield
With potassium hydroxide In ethanol; water for 26h; Heating;	85%
Stage #1: 2-amino-3-hydroxy-phenazine With potassium hydroxide In ethanol; water Heating; Stage #2: carbon disulfide In ethanol; water at 20℃;	60%
With potassium hydroxide In ethanol; water
With potassium hydroxide
With potassium hydroxide In ethanol; water at 80℃; for 26h;

: 4569-77-1
2-amino-3-hydroxy-phenazine

: 1122-91-4
4-bromo-benzaldehyde

: 109-77-3
malononitrile

: 3,5-diamino-1-(4-bromophenyl)-1H-pyrano[3,2-a]phenazine-2-carbonitrile

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In ethanol Reflux;	85%

...Expand

: 4569-77-1
2-amino-3-hydroxy-phenazine

: 555-16-8
4-nitrobenzaldehdye

: 105-56-6
ethyl 2-cyanoacetate

: ethyl 3,5-diamino-1-(4-nitrophenyl)-1H-pyrano[3,2-a]phenazine-2-carboxylate

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In ethanol Reflux;	85%

...Expand

: 4569-77-1
2-amino-3-hydroxy-phenazine

: 105-56-6
ethyl 2-cyanoacetate

: 6287-38-3
3,4-dichlorobenzaldehyde

: ethyl 3,5-diamino-1-(3,4-dichlorophenyl)-1H-pyrano[3,2-a]phenazine-2-carboxylate

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In ethanol Reflux;	85%

...Expand

: 4569-77-1
2-amino-3-hydroxy-phenazine

: 6948-30-7
5-bromoveratralaldehyde

: 105-56-6
ethyl 2-cyanoacetate

: ethyl 3,5-diamino-1-(3-bromo-4,5-dimethoxyphenyl)-1H-pyrano[3,2-a]phenazine-2-carboxylate

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In ethanol Reflux;	85%

...Expand

: 4569-77-1
2-amino-3-hydroxy-phenazine

: 351-54-2
3-fluoro-p-anisaldehyde

: 109-77-3
malononitrile

: 3,5-diamino-1-(3-fluoro-4-methoxyphenyl)-1H-pyrano[3,2-a]phenazine-2-carbonitrile

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In ethanol Reflux;	84%

...Expand

: 4569-77-1
2-amino-3-hydroxy-phenazine

: 351-54-2
3-fluoro-p-anisaldehyde

: 105-56-6
ethyl 2-cyanoacetate

: ethyl 3,5-diamino-1-(3-fluoro-4-methoxyphenyl)-1H-pyrano[3,2-a]phenazine-2-carboxylate

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In ethanol Reflux;	84%

...Expand

: 4569-77-1
2-amino-3-hydroxy-phenazine

: 105-56-6
ethyl 2-cyanoacetate

: 4748-78-1
4-ethylbenzylaldehyde

: ethyl 3,5-diamino-1-(4-ethylphenyl)-1H-pyrano[3,2-a]phenazine-2-carboxylate

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In ethanol Reflux;	83%

...Expand

: 4569-77-1
2-amino-3-hydroxy-phenazine

: 83-38-5
2,6-dichlorobenzaldehyde

: 105-56-6
ethyl 2-cyanoacetate

: ethyl 3,5-diamino-1-(2,6-dichlorophenyl)-1H-pyrano[3,2-a]phenazine-2-carboxylate

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In ethanol Reflux;	83%

...Expand

: 4569-77-1
2-amino-3-hydroxy-phenazine

: 104-88-1
4-chlorobenzaldehyde

: 109-77-3
malononitrile

: 3,5-diamino-1-(4-chlorophenyl)-1H-pyrano[3,2-a]phenazine-2-carbonitrile

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In ethanol Reflux;	82%

...Expand

: 4569-77-1
2-amino-3-hydroxy-phenazine

: 122-03-2
(4-isopropylbenzaldehyde)

: 109-77-3
malononitrile

: 3,5-diamino-1-(4-isopropylphenyl)-1H-pyrano[3,2-a]phenazine-2-carbonitrile

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In ethanol Reflux;	82%

...Expand

: 4569-77-1
2-amino-3-hydroxy-phenazine

: 109-77-3
malononitrile

: 134-96-3
syringic aldehyde

: 3,5-diamino-1-(4-hydroxy-3,5-dimethoxyphenyl)-1H-pyrano[3,2-a]phenazine-2-carbonitrile

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In ethanol Reflux;	82%

...Expand

: 4569-77-1
2-amino-3-hydroxy-phenazine

: 31558-40-4
4-bromo-3,5-dimethoxybenzaldehyde

: 109-77-3
malononitrile

: 3,5-diamino-1-(4-bromo-3,5-dimethoxyphenyl)-1H-pyrano[3,2-a]phenazine-2-carbonitrile

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In ethanol Reflux;	82%

...Expand

: 4569-77-1
2-amino-3-hydroxy-phenazine

: 587-04-2
3-Chlorobenzaldehyde

: 109-77-3
malononitrile

: 3,5-diamino-1-(3-chlorophenyl)-1H-pyrano[3,2-a]phenazine-2-carbonitrile

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In ethanol Reflux;	81%

...Expand

: 4569-77-1
2-amino-3-hydroxy-phenazine

: 6287-38-3
3,4-dichlorobenzaldehyde

: 109-77-3
malononitrile

: 3,5-diamino-1-(3,4-dichlorophenyl)-1H-pyrano[3,2-a]phenazine-2-carbonitrile

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In ethanol Reflux;	81%

...Expand

: 4569-77-1
2-amino-3-hydroxy-phenazine

: 99-61-6
3-nitro-benzaldehyde

: 105-56-6
ethyl 2-cyanoacetate

: ethyl 3,5-diamino-1-(3-nitrophenyl)-1H-pyrano[3,2-a]phenazine-2-carboxylate

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In ethanol Reflux;	81%

...Expand

: 4569-77-1
2-amino-3-hydroxy-phenazine

: 1122-91-4
4-bromo-benzaldehyde

: 105-56-6
ethyl 2-cyanoacetate

: ethyl 3,5-diamino-1-(4-bromophenyl)-1H-pyrano[3,2-a]phenazine-2-carboxylate

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In ethanol Reflux;	81%

...Expand

: 4569-77-1
2-amino-3-hydroxy-phenazine

: 555-16-8
4-nitrobenzaldehdye

: 109-77-3
malononitrile

: 3,5-diamino-1-(4-nitrophenyl)-1H-pyrano[3,2-a]phenazine-2-carbonitrile

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In ethanol Reflux;	80%

...Expand

2-Amino-3-hydroxyphenazine Chemical Properties

The IUPAC name of 2-Amino-3-hydroxyphenazine (CAS NO.4569-77-1): 3-Amino-10H-phenazin-2-one
Synonyms: 2-Amino-3-phenazinol ; 3-Amino-2-phenazino ; 3-Amino-2-Phenazinol
CAS: 4569-77-1
Molecular Formula:C₁₂H₉N₃O
Molecular Structure:

Formula Weight: 211.22 g/mol
Index of Refraction: 1.758
Density: 1.46 g/cm³
Flash Point: 184.6 °C
Boiling Point: 381.6 °C at 760 mmHg

2-Amino-3-hydroxyphenazine Toxicity Data With Reference

The toxicity information of 2-Amino-3-hydroxyphenazine (CAS NO.4569-77-1):

mic-bac-sat 80 ng/plate

MUREAV Mutation Research. 321 (1994),43.

2-Amino-3-hydroxyphenazine Safety Profile

The Hazard Codes of 2-Amino-3-hydroxyphenazine (CAS NO.4569-77-1): Irritant Xi
Mutation data reported. When heated to decomposition it emits toxic vapors of NO_x.

Product Name

3-AMINO-PHENAZIN-2-OL

Synthetic route

2-Amino-3-hydroxyphenazine Chemical Properties

2-Amino-3-hydroxyphenazine Toxicity Data With Reference

2-Amino-3-hydroxyphenazine Safety Profile

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