2-Amino-4,6-dimethoxypyrimidine supplier

Name
2-Amino-4,6-dimethoxypyrimidine
EINECS 252-969-6
CAS No. 36315-01-2
Article Data45
CAS DataBase
Density 1.229 g/cm³
Solubility
Melting Point 94-96 °C(lit.)
Formula C₆H₉N₃O₂
Boiling Point 356.4 °C at 760 mmHg
Molecular Weight 155.156
Flash Point 169.4 °C
Transport Information
Appearance crystalline powder
Safety 26-36/37/39
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms 4,6-Dimethoxypyrimidin-2-amine;2-Amino-4,6-dimethoxypyridine;2-Amino-4,6-methoxy pyrimidine;4,6-Dimethoxy-pyrimidin-2-ylamine;2-amino-4,6-dimethoxy pyrimidine(ADMP);
PSA 70.26000
LogP 0.65720

Synthetic route

: N-benzyl-2-amino-4,6-dimethoxypyrimidine

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

Conditions

Conditions	Yield
With methanol; palladium(II) hydroxide at 20℃; for 48h;	98%
With hydrogen; palladium(II) hydroxide In methanol at 20℃; under 760.051 Torr; for 48h;	98%

: 13223-25-1
2-chloro-4,6-dimethoxypyrimidine

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

Conditions

Conditions	Yield
With ammonia In tetrahydrofuran; water at 100 - 110℃; for 4h; Solvent; Autoclave; Large scale;	96.3%
With dicyclohexyl(2',4',6'-triisopropyl-5-methoxy-3,4,6-trimethyl-[1,1'-biphenyl]-2-yl)phosphine; C50H70NO4PPdS; C50H70NO4PPdS; dicyclohexyl(2',4',6'-triisopropyl-4-methoxy-3,5,6-trimethyl-[1,1'-biphenyl]-2-yl)phosphine; ammonia; sodium t-butanolate In 1,4-dioxane at 50℃; for 24h; Reagent/catalyst; Inert atmosphere;	80%
Multi-step reaction with 2 steps 1: potassium carbonate / 1,4-dioxane / 96 h / Reflux 2: methanol; palladium(II) hydroxide / 48 h / 20 °C View Scheme
Multi-step reaction with 2 steps 1: potassium carbonate / 1,4-dioxane / 96 h / Reflux 2: hydrogen; palladium(II) hydroxide / methanol / 48 h / 20 °C / 760.05 Torr View Scheme

: 3-amino-3-methoxy-N-nitrile-2-propionamidine

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

Conditions

Conditions	Yield
Stage #1: 3-amino-3-methoxy-N-nitrile-2-propionamidine With acetic acid In toluene at 150℃; for 3h; Industrial scale; Stage #2: In toluene Reagent/catalyst; Temperature; Industrial scale;	96%
With acetic acid at 120 - 130℃; for 4h; Reagent/catalyst; Large scale;	95.47%
In toluene at 100℃; for 5h;	82.06%

: C9H13N3O2

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

Conditions

Conditions	Yield
With hydrogenchloride In water at 40 - 45℃; for 4h; Temperature;	91.3%

: 67-56-1
methanol

: 56-05-3
2-Amino-4,6-dichloropyrimidine

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

Conditions

Conditions	Yield
Stage #1: methanol With sodium hydride In tetrahydrofuran for 0.25h; Inert atmosphere; Stage #2: 2-Amino-4,6-dichloropyrimidine In tetrahydrofuran for 15h; Inert atmosphere;	91%
With sodium for 13h; Reflux;	85%
With sodium at 20℃; for 85h; Reflux;	85%
With sodium

: C10H15N3O2

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

Conditions

Conditions	Yield
With hydrogenchloride In water at 60 - 65℃; for 3h;	90.6%

: potassium bicarbonate

: 420-04-2
CYANAMID

: 71160-05-9
dimethyl 1,3-propanediimidate dihydrochloride

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

Conditions

Conditions	Yield
In water; toluene	90%

...Expand

: methyl 3-amino-3-methoxy-N-nitrile-2-propionamidine

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

Conditions

Conditions	Yield
Stage #1: methyl 3-amino-3-methoxy-N-nitrile-2-propionamidine With zinc(II) chloride In toluene at 65℃; for 3h; Stage #2: With hydrogenchloride In toluene at 20℃; for 2h; Solvent; Reagent/catalyst; Temperature;	90%
at 105℃; for 7h; Temperature;	80%
In methanol for 6h; Solvent; Reflux;	125g

: potassium bicarbonate

: 420-04-2
CYANAMID

: 71160-05-9
dimethyl 1,3-propanediimidate dihydrochloride

: 108-10-1
4-methyl-2-pentanone

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

Conditions

Conditions	Yield
In water	89.8%

...Expand

: potassium bicarbonate

: 71160-05-9
dimethyl 1,3-propanediimidate dihydrochloride

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

Conditions

Conditions	Yield
In water; toluene	89.3%

: 186581-53-3, 908094-01-9
diazomethane

: 56-09-7
2-aminopyrimidine-4,6-diol

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

Conditions

Conditions	Yield
In methanol; diethyl ether at 20℃; for 24h;	86%
In methanol; diethyl ether at 20℃; for 24h;	86%

: 56-05-3
2-Amino-4,6-dichloropyrimidine

: 124-41-4
sodium methylate

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

Conditions

Conditions	Yield
With methanol
With methanol; xylene
In methanol at 20℃; Substitution;

: azimsulfuron

A: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

B: 1-methyl-4-(2-methyl-2H-tetrazole-5-yl)-1H-pyrazole-5-sulfonamide

Conditions

Conditions	Yield
With sodium hydroxide at 50℃; Rate constant; Thermodynamic data; effect of acidic conditions (pH 1.4-5.6); effect of temperatures(40-50 deg C); ΔH; ΔS; effect of ionic strength on alkaline hydrolysis of title comp.;
With iron oxide; water at 25℃; pH=4.8; Kinetics; Further Variations:; Reagents;

: 144740-54-5
methyl 2-[[[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]amino]sulfonyl]-6-(trifluoromethyl)-3-pyridinecarboxylate monosodium salt

A: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

B: 144740-59-0
methyl 2-(aminosulfonyl)-6-(trifluoromethyl)-3-pyridinecarboxylate

C: 1-(4,6-dimethoxy-2-pyrimidinyl)-7-(trifluoromethyl)pyrido [2,3-d]pyrimidine-2,4(1H,3H)-dione

D: methyl 2-[(aminocarbonyl)(4,6-dimethoxy-2-pyrimidinyl)amino]-6-trifluoromethyl-3-pyridinecarboxylate

Conditions

Conditions	Yield
With acetate buffer at 20℃; for 720h; pH=5; Product distribution; Kinetics; Further Variations:; Temperatures; Hydrolysis; rearrangement;

...Expand

: 67-56-1
methanol

: 111991-09-4
nicosulfuron

A: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

B: [[3-[(Dimethylamino)carbonyl]-2-pyridinyl]sulfonyl]carbamic acid methyl ester

Conditions

Conditions	Yield
at 30℃; Kinetics;

...Expand

: 64-17-5
ethanol

: 111991-09-4
nicosulfuron

A: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

B: [3-(N,N-dimethylcarbamoyl)-2-pyridyl]sulfonylcarbamate ethyl ester

Conditions

Conditions	Yield
at 30℃; Kinetics;

...Expand

: 111991-09-4
nicosulfuron

A: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

B: 112006-75-4
N,N-dimethyl-2-(aminosulfonyl)-3-pyridinecarboxamide

Conditions

Conditions	Yield
With disodium hydrogenphosphate; citric acid at 30℃; pH=4; Kinetics; Further Variations:; pH-values;

dimethyl carboximidate: dimethyl carboximidate

: 51534-05-5
dimethyl 1,3-propanediimidate

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

Conditions

Conditions	Yield
With potassium carbonate In acetonitrile

aqueous cyanamide: aqueous cyanamide

: methyl 3-amino-3-methoxy-N-cyano-2-propeneimidate

: 71160-05-9
dimethyl 1,3-propanediimidate dihydrochloride

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

Conditions

Conditions	Yield
With sodium hydroxide In 5,5-dimethyl-1,3-cyclohexadiene; dichloromethane; water

...Expand

: methyl 3-amino-3-methoxy-N-cyano-2-propeneimidate

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

Conditions

Conditions	Yield
In toluene

: azimsulfuron

A: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

B: 947599-43-1
6-amino-5-[(4,6-dimethoxypyrimidin-2-yl)methylamino]-1,5,6,8-tetrahydro-7-oxa-8λ6-tia-1,2,5,6-tetraaza-azulen-4-one

C: N-(4,6-dimethoxy-2-pyrimidinyl)urea

Conditions

Conditions	Yield
In water; acetonitrile for 24h; Irradiation;

...Expand

: azimsulfuron

A: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

B: 947599-44-2
N-[[(5-hydroxy-4,6-dimethoxypyrimidin-2-yl)amino]carbonyl]-1-methyl-4-(2-methyl-2H-tetrazole-5-yl)-1H-pyrazole-5-sulfonamide

C: 1-methyl-4-(2-methyl-2H-tetrazole-5-yl)-1H-pyrazole-5-sulfonamide

Conditions

Conditions	Yield
With iron(III) oxide In water Irradiation;

...Expand

: 56-09-7
2-aminopyrimidine-4,6-diol

: 616-38-6
carbonic acid dimethyl ester

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

Conditions

Conditions	Yield
With tetrabutylammomium bromide; potassium carbonate In N,N-dimethyl-formamide at 150℃; Temperature; Time; Reagent/catalyst; Concentration;

: 120923-37-7
amidosulfuron

A: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

B: (5-hydroxy-4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl-N-methylsulfamic acid

C: (5-hydroxy-4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamic acid

D: (4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamic acid

E: 1-(4-hydroxy-6-methoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea

F: 1-(5-hydroxy-4,6-dimethoxy-pyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea

G: N-(4,6-dimethoxy-2-pyrimidinyl)urea

Conditions

Conditions	Yield
In water at 30℃; Irradiation;

...Expand

: C6H11N3O2S

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

Conditions

Conditions	Yield
In 5,5-dimethyl-1,3-cyclohexadiene at 110 - 120℃; for 0.5h; Solvent; Temperature;	285 g

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

: C11H13N3O7S

: N, N-dimethyl-2-(N-(N-(4,6-dimethoxypyrimidin-2-yl)-aminocarbonyl)-aminosulfonyl)-4-nitrobenzamide

Conditions

Conditions	Yield
In toluene Reflux;	98.4%

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

: [3-(N,N-dimethylcarbamoyl)-2-pyridyl]sulfonylcarbamate ethyl ester

: 111991-09-4
nicosulfuron

Conditions

Conditions	Yield
With calcium chloride In toluene Autoclave; Heating; Large scale;	98.4%
With tetrabutyl phosphonium bromide In acetonitrile at 60 - 100℃; for 5h; Reagent/catalyst;	97.13%
In toluene for 0.5h; Reflux;	75.6%

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

: ethyl (N-methylsulfonyl-N-methylamino)sulfonylcarbamate

: 120923-37-7
amidosulfuron

Conditions

Conditions	Yield
In chlorobenzene	97.2%

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

: 578-57-4
2-bromoanisole

: 1627898-11-6
4,6-dimethoxy-2-[(2-methoxyphenyl)amino]pyrimidine

Conditions

Conditions	Yield
With tris-(dibenzylideneacetone)dipalladium(0); 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene; sodium t-butanolate In toluene at 95℃; Buchwald-Hartwig Coupling; Schlenk technique; Inert atmosphere;	97%

: 2-ethoxyphenyl N-(2-ethoxyphenoxysulfonyl)carbamate

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

A: 94-71-3
2-Ethoxyphenol

B: 126801-58-9
ethoxysulfuron

Conditions

Conditions	Yield
In toluene	A n/a B 96.4%

...Expand

: 108-86-1
bromobenzene

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

: 4,6-dimethoxy-N-phenylpyrimidin-2-ylamine

Conditions

Conditions	Yield
With tris-(dibenzylideneacetone)dipalladium(0); 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene; sodium t-butanolate In toluene at 95℃; Reagent/catalyst; Solvent; Buchwald-Hartwig Coupling; Schlenk technique; Inert atmosphere;	96%

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

: phenyl N-{[3-(dimethylcarbamoyl)pyridin-2-yl]sulfonyl}carbamate

: 111991-09-4
nicosulfuron

Conditions

Conditions	Yield
In dichloromethane at 40℃; for 5h; Temperature; Large scale;	95.47%

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

: 144851-58-1
N-[(N'-methyl-N'-methylsulfonyl-aminosulfonyl)-aminocarbonyl]-morpholine

: 120923-37-7
amidosulfuron

Conditions

Conditions	Yield
In toluene	95%

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

: 824-94-2
p-methoxybenzyl chloride

: 1268273-15-9
4,6-dimethoxy-N,N-bis(4-methoxybenzyl)pyrimidin-2-amine

Conditions

Conditions	Yield
Stage #1: 4,6-dimethoxy-2-aminopyrimidine With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; Inert atmosphere; Stage #2: p-methoxybenzyl chloride In N,N-dimethyl-formamide at 20℃;	95%
Stage #1: 4,6-dimethoxy-2-aminopyrimidine With sodium hydride In N,N-dimethyl-formamide; mineral oil at 20℃; for 0.166667h; Inert atmosphere; Stage #2: p-methoxybenzyl chloride In N,N-dimethyl-formamide; mineral oil at 20℃; Inert atmosphere;	95%

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

: 108-36-1
1,3-dibromobenzene

: 1627898-13-8
2-[(3-bromophenyl)amino]-4,6-dimethoxypyrimidine

Conditions

Conditions	Yield
With tris-(dibenzylideneacetone)dipalladium(0); 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene; sodium t-butanolate In toluene at 95℃; Buchwald-Hartwig Coupling; Schlenk technique; Inert atmosphere;	94%

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

: C10H8INO6S

: sodium ((4,6-dimethoxypyrimidin-2-yl)carbamoyl)((2-((2-iodoethoxy)carbonyl)phenoxy)sulfonyl)amide

Conditions

Conditions	Yield
Stage #1: 4,6-dimethoxy-2-aminopyrimidine; C10H8INO6S In acetonitrile at 20℃; for 24h; Stage #2: With sodium hydrogencarbonate	94%

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

: 68-11-1
mercaptoacetic acid

: 105-07-7
4-cyanobenzaldehyde

: 1610829-11-2
4-(3-(4,6-dimethoxypyrimidin-2-yl)-4-oxothiazolidin-2-yl)benzonitrile

Conditions

Conditions	Yield
In toluene Reflux; Dean-Stark;	93.1%

...Expand

: 1-[(N-methylsulfonyl-N-methylamino)-sulfonyl]-3-(N-methylsulfonyl-N-methylamino)urea

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

A: 1184-85-6
N-methylmethane sulphonamide

B: 120923-37-7
amidosulfuron

Conditions

Conditions	Yield
In chlorobenzene	A n/a B 92.7%

...Expand

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

: 917-61-3
sodium isocyanate

: 112006-58-3
2-sulfonyl chloride-N,N-dimethylnicotinamide

: 111991-09-4
nicosulfuron

Conditions

Conditions	Yield
Stage #1: sodium isocyanate; 2-sulfonyl chloride-N,N-dimethylnicotinamide With triethylamine In acetonitrile at 25℃; for 5h; Stage #2: 4,6-dimethoxy-2-aminopyrimidine In acetonitrile at 0 - 40℃; for 1h; Temperature;	92.1%

...Expand

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

: 3-Isocyanatosulfonyl-1-methyl-1H-indole-2-carboxylic acid methyl ester

: 3-[[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]aminosulfonyl]-1-methyl-1H-indole-2-carboxylic acid, methyl ester

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In benzene for 4h; Heating;	92%

: methyl 3-chloro-1-methyl-4-(5-methyl-5,6-dihydro-1,4,2-dioxazine-3-yl)-1H-pyrazole-5-ylsulfonylcarbamate

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

: 1-{3-chloro-1-methyl-4-[5,6-dihydro-5-methyl-1,4,2-dioxazin-3-yl]pyrazol-5-ylsulfonyl}-3-(4,6-dimethoxypyrimidin-2-yl)urea

Conditions

Conditions	Yield
In n-heptane; o-xylene at 90℃; under 337.534 Torr; for 12h;	91.9%
In toluene for 4h; Product distribution / selectivity; Heating / reflux;

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

: 16182-04-0
Ethoxycarbonyl isothiocyanate

: 13223-43-3
5,7-dimethoxy-[1,2,4]-triazolo-[1,5-a]-pyrimidin-2-amine

Conditions

Conditions	Yield
Stage #1: 4,6-dimethoxy-2-aminopyrimidine; Ethoxycarbonyl isothiocyanate In ethyl acetate at 78℃; for 5.33333h; Heating / reflux; Stage #2: With hydroxyammonium sulfate In water; ethyl acetate at 71℃; Heating / reflux; Stage #3: With sodium carbonate In water; ethyl acetate at 71℃; for 7h; pH=6.5 - 7.0; Heating / reflux;	91.1%

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

: 2398-37-0
3-methoxyphenyl bromide

: 1627898-10-5
4,6-dimethoxy-2-[(3-methoxyphenyl)amino]pyrimidine

Conditions

Conditions	Yield
With tris-(dibenzylideneacetone)dipalladium(0); 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene; sodium t-butanolate In toluene at 95℃; Buchwald-Hartwig Coupling; Schlenk technique; Inert atmosphere;	91%

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

: 437-81-0
2,6-difluorobenzaldehyde

: 68-11-1
mercaptoacetic acid

: 1610829-33-8
2-(2,6-difluorophenyl)-3-(4,6-dimethoxypyrimidin-2-yl)thiazolidin-4-one

Conditions

Conditions	Yield
In toluene Reflux; Dean-Stark;	90.2%

...Expand

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

: C15H19NO6S

: methyl (E)-3-(3-(N-((4,6-dimethoxypyrimidin-2-yl)carbamoyl)sulfamoyl)-4-methylphenyl)-2-methylacrylate

Conditions

Conditions	Yield
In ethanol; toluene Reflux;	90.1%

: 36315-01-2
4,6-dimethoxy-2-aminopyrimidine

: 201230-82-2
carbon monoxide

: 98-46-4
3-trifluoromethylnitrobenzene

: N-(3-trifluoromethylphenyl)-N'-(4,6-dimethoxy-2-pyrimidyl)urea

Conditions

Conditions	Yield
With triethylamine; selenium(IV) oxide In toluene at 140 - 150℃; under 22501.8 Torr; for 4h;	89.8%

...Expand

2-Amino-4,6-dimethoxypyrimidine Specification

The 2-Amino-4,6-dimethoxypyrimidine with the cas number 36315-01-2, is also called (4,6-Dimethoxypyrimidin-2-amine named by IUPAC. 2-Amino-4,6-dimethoxypyrimidine belongs to the following product categories: (1)Pyridines ; (2)Pyrimidines ; (3)Purines and Pteredines; (4)Pyrimidine; (5)Amines; (6)Pyrimidines; (7)Building Blocks; (8)Heterocyclic Building Blocks.

Properties of 2-Amino-4,6-dimethoxypyrimidine: (1)H bond acceptors: 5 ; (2)H bond donors: 2 ; (3)Freely Rotating Bonds: 2 ; (4)Polar Surface Area: 47.48 Å ; (5)Index of Refraction: 1.547 ; (6)Molar Refractivity: 40.02 cm³ ; (7)Molar Volume: 126.1 cm³ ; (8)Polarizability: 15.86× 10^-24cm³ ; (9)Surface Tension: 49.5 dyne/cm ; (10)Density: 1.229 g/cm³ ; (11)Flash Point: 169.4 °C ; (12)Enthalpy of Vaporization: 60.17 kJ/mol ; (13)Boiling Point: 356.4 °C at 760 mmHg ; (14)Vapour Pressure: 2.92E-05 mmHg at 25°C

Uses of 2-Amino-4,6-dimethoxypyrimidine: This product is a kind of important pesticide intermediates for synthesis of sulfonylurea pesticide, such as bensulfuron methyl , Nicosulfuron , cyclosulfamuron , Ethoxysulfuron , Rimsulfuron , Azimsulfuron and so on.

Preparation of 2-Amino-4,6-dimethoxypyrimidine: (1)It is mainly produced by raw materials such as propylene nitriles, methanol, cyanamide. (2) Reaction of N,N-Dimethylaniline, with 2-Amino-4,6-dihydroxypyrimidine and phosphorus oxychloride to produce 2-Amino-4,6-dichloropyrimidine. Then react with sodium methoxide to obtain 2-Amino-4,6-dimethoxypyrimidine.

When you are using this chemical, please be cautious about it as the following:
Firstly, 2-Amino-4,6-dimethoxypyrimidine is irritating not only to eyes, respiratory system but also is irritating to skin. When using it, please wear suitable protective clothing, gloves and eye/face protection. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure :
1. SMILES: O(c1nc(nc(OC)c1)N)C
2. InChI: InChI=1/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)

Product Name

2-Amino-4,6-dimethoxypyrimidine

Synthetic route

2-Amino-4,6-dimethoxypyrimidine Specification

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