2-Aminophenol hydrochloride supplier

Name
2-AMINOPHENOL HYDROCHLORIDE
EINECS 202-431-1
CAS No. 51-19-4
Article Data6
CAS DataBase
Density 1.21 g/cm³
Solubility almost transparency
Melting Point 207 °C
Formula C6H7 N O . Cl H
Boiling Point 234.5 °C at 760 mmHg
Molecular Weight 145.589
Flash Point 95.6 °C
Transport Information
Appearance
Safety
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms o-Hydroxyanilinehydrochloride;o-Aminophenol hydrochloride;Phenol, o-amino-, hydrochloride (8CI);Phenol,2-amino-, hydrochloride (9CI);
PSA 46.25000
LogP 2.35760

Synthetic route

: 95-55-6
2-amino-phenol

: 51-19-4
2-aminophenol hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride In methanol for 15h; Inert atmosphere;	90%
With hydrogenchloride In methanol at 20℃; for 15h; pH=2 - 5;
With hydrogenchloride In water

: 7653-60-3
3-methyl-1,4-benzoxazin-2-one

: 64-17-5
ethanol

A: 617-35-6
2-oxo-propionic acid ethyl ester

B: 51-19-4
2-aminophenol hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride for 0.25h; boiling water bath;

...Expand

: 3-carboxyethylbenzoxazinone

A: 328-50-7
α-ketoglutaric acid

B: 51-19-4
2-aminophenol hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride In ethanol for 0.25h; boiling water bath;

: 64-17-5
ethanol

: 27990-57-4
3-phenyl-1,4-benzoxazin-2-one

A: 1603-79-8
phenylglyoxylic acid ethyl ester

B: 51-19-4
2-aminophenol hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride for 0.25h; boiling water bath;

...Expand

: 88-75-5
2-hydroxynitrobenzene

: 51-19-4
2-aminophenol hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride; tin(ll) chloride In ethanol; water at 30℃; Rate constant; Mechanism; various concentration of HCl; different amounts of H2O as solvent;

: 3913-17-5
2-chloro-4,8-dimethyl-quinoline

: 51-19-4
2-aminophenol hydrochloride

: 1436858-64-8
2-(4,8-dimethylquinolin-2-ylamino)phenol hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride In ethanol; water Heating;	92%

: 3913-18-6
2-chloro-4,6-dimethylquinoline

: 51-19-4
2-aminophenol hydrochloride

: 1436858-58-0
2-(4,6-dimethylquinolin-2-ylamino)phenolhydrochloride

Conditions

Conditions	Yield
With hydrogenchloride In ethanol; water Heating;	86%

: 51-19-4
2-aminophenol hydrochloride

: 2007-97-8
trichloro(o-phenylenedioxy)phosphorane

: 66258-52-4
2λ5,13'λ5-dispiro[benzo[1,3,2]dioxaphosphole-2,6'-dibenzo[d,d'][1,3,2,4]diazadiphospheto[2,1-b;4,3-b']bis[1,3,2]oxazaphosphole-13',2''-benzo[1,3,2]dioxaphosphole]

Conditions

Conditions	Yield
	85%

: 1147550-11-5
ammonium thiocyanate

: 51-19-4
2-aminophenol hydrochloride

: 1520-26-9
2-hydroxyphenylthiourea

Conditions

Conditions	Yield
at 120 - 130℃; for 0.75h;	83%

: 10200-59-6
Thiazole-2-carbaldehyde

: 51-19-4
2-aminophenol hydrochloride

: (E)-2-((thiazol-2-ylmethylene)amino)phenol

Conditions

Conditions	Yield
With triethylamine In toluene at 50℃; for 24h;	81.6%

: 634-47-9
2-chloro-4-methylquinoline

: 51-19-4
2-aminophenol hydrochloride

: 1436858-53-5
2-(4-methylquinolin-2-ylamino)phenol hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride In ethanol; water Heating;	81%

: 51-19-4
2-aminophenol hydrochloride

: 104-15-4
toluene-4-sulfonic acid

: 2-hydroxyphenylhydrazine p-toluenesulfonic acid salt

Conditions

Conditions	Yield
Stage #1: 2-aminophenol hydrochloride With isopentyl nitrite In ethanol at -5 - 0℃; Stage #2: toluene-4-sulfonic acid With tin(ll) chloride In ethanol at 0 - 5℃; for 1h;	80%
With tin(ll) chloride; isopentyl nitrite 1) EtOH, 0 deg C, 2) EtOH, 0 deg C, 30 min; Yield given. Multistep reaction;

: 1038222-56-8
3-(3-phenoxybenzylamino)propionitrile

: 51-19-4
2-aminophenol hydrochloride

: 1347646-76-7
2-[2-(3-phenoxybenzylamino)ethyl]benzoxazole

Conditions

Conditions	Yield
at 190 - 200℃; Neat (no solvent); Sealed ampoule;	80%

: 51632-29-2
3-phenoxyphenylacetonitrile

: 51-19-4
2-aminophenol hydrochloride

: 1347646-70-1
2-(3-phenoxybenzyl)benzoxazole

Conditions

Conditions	Yield
at 190 - 200℃; Neat (no solvent); Sealed ampoule;	80%

: 51-19-4
2-aminophenol hydrochloride

: 2-hydroxyphenylhydrazine p-toluenesulfonic acid salt

Conditions

Conditions	Yield
Stage #1: 2-aminophenol hydrochloride With isopentyl nitrite In ethanol at -5℃; Stage #2: With tin(IV) chloride; toluene-4-sulfonic acid In ethanol at -5℃; for 1h;	80%

: 1347646-61-0
C15H11NO

: 51-19-4
2-aminophenol hydrochloride

: 1062114-84-4
2-[(E)-2-(3-phenoxyphenyl)vinyl]benzoxazole

Conditions

Conditions	Yield
With hydroquinone at 190 - 200℃; Neat (no solvent); Sealed ampoule;	76%

: 50789-45-2
3-phenoxybenzonitrile

: 51-19-4
2-aminophenol hydrochloride

2-(3-phenoxyphenyl)benzoxazole: 1152493-76-9
2-(3-phenoxyphenyl)benzoxazole

Conditions

Conditions	Yield
at 190 - 200℃; Neat (no solvent); Sealed ampoule;	74%

: 67-56-1
methanol

: 51-19-4
2-aminophenol hydrochloride

copper: copper

: Phenylmalondialdehyd-natrium salz

: Cu3((bis[(2-mercapto)anil] of phenylmalonaldehyde)-3H)2*methanol

Conditions

Conditions	Yield
In methanol Electrolysis; in electrochem. cell contg. MeOH soln. of sodium phenylmalonaldehyde ando-aminophenol hydrochloride; Cu was a sol. anode; Pt was a cathode; LiC lO4 was a background electrolyte; electrolysis was performed at 20 mA and 20 V within 4 h at room temp.; the ppt. was filtered off, washed with hot methanol, and dried in a vac.oven at 150°C; elem. anal.;	70%

...Expand

: 75-15-0
carbon disulfide

: 51-19-4
2-aminophenol hydrochloride

: 2382-96-9
benzo[d]oxazole-2-(3H)-thione

Conditions

Conditions	Yield
With triethylamine In dichloromethane for 16h; Inert atmosphere; Reflux;	70%

: 51-19-4
2-aminophenol hydrochloride

: 115423-03-5
ethyl 4-amino-3-cyanopyrazolo<5,1-c><1,2,4>triazine-8-carboxylate

A: 116507-25-6
9-ethoxycarbonyl-6-oxo-5,6-dihydropyrazolo<1',5':3,4><1,2,4>triazino<5,6-b><1,5>benzoxazepine

B: 116507-28-9
9-ethoxycarbonyl-6-(o-hydroxyphenyl)aminopyrazolo<1',5':3,4><1,2,4>triazino<5,6-b><1,5>benzoxazepine

Conditions

Conditions	Yield
In acetic acid for 5h; Heating;	A 22% B 68%

...Expand

: 696-59-3
cis,trans-2,5-dimethoxytetrahydrofuran

: 51-19-4
2-aminophenol hydrochloride

: 32277-91-1
2-(1H-pyrrol-1-yl)phenol

Conditions

Conditions	Yield
With nicotinamide In 1,4-dioxane for 9h; Clauson-Kaas Synthesis; Reflux; Inert atmosphere;	67%

: 51-19-4
2-aminophenol hydrochloride

: 115423-04-6
4-amino-3,8-bisethoxycarbonylpyrazolo<5,1-c><1,2,4>triazine

: 116507-25-6
9-ethoxycarbonyl-6-oxo-5,6-dihydropyrazolo<1',5':3,4><1,2,4>triazino<5,6-b><1,5>benzoxazepine

Conditions

Conditions	Yield
In acetic acid for 5h; Heating;	66%

: 51-19-4
2-aminophenol hydrochloride

: 153788-24-0
7-chloro-4-(2-cyano-2-hydroxyvinyl)tetrazolo<1,5-a>quinoxaline

: 4-<2-(2-benzoxazolyl)-2-hydroxyvinyl>-7-chlorotetrazolo<1,5-a>quinoxaline

Conditions

Conditions	Yield
With acetic acid for 2h; Heating;	65%

: 1185760-64-8
3-(3-phenoxyphenyl)-2-butenonitrile

: 51-19-4
2-aminophenol hydrochloride

: 1347646-73-4
2-[2-(3-phenoxyphenyl)propen-1-en-1-yl]benzoxazole

Conditions

Conditions	Yield
With hydroquinone at 190 - 200℃; Neat (no solvent); Sealed ampoule;	64%

: 1243274-72-7
2-methyl-2-(3-phenoxybenzoyloxy)propionitrile

: 51-19-4
2-aminophenol hydrochloride

: 1347646-79-0
1-(benzoxazol-2-yl)-1-methylethyl-3-phenoxybenzoate

Conditions

Conditions	Yield
at 190 - 200℃; Neat (no solvent); Sealed ampoule;	62%

: 1057676-70-6
3-(3-phenoxyphenyl)propanenitrile

: 51-19-4
2-aminophenol hydrochloride

: 1347646-75-6
2-[2-(3-phenoxyphenyl)ethyl]benzoxazole

Conditions

Conditions	Yield
at 190 - 200℃; Neat (no solvent); Sealed ampoule;	56%

: 51-19-4
2-aminophenol hydrochloride

: 163339-67-1
methyl 2-bromo-2-(3-bromophenyl)acetate

: 244621-27-0
2-(3-bromophenyl)-3,4-dihydro-2H-1,4-benzoxazin-3-one

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 20℃; for 24h; cyclocondensation;	55%

: 1264878-02-5
3-phenoxyphenylmethoxypropionitrile

: 51-19-4
2-aminophenol hydrochloride

: 1347646-77-8
2-{2-[(3-phenoxybenzyl)oxy]ethyl}benzoxazole

Conditions

Conditions	Yield
at 190 - 200℃; Neat (no solvent); Sealed ampoule;	51%

: 51-19-4
2-aminophenol hydrochloride

: 141238-66-6
ethyl 3-amino-4,5-diphenyl-1(H)-pyrrolo<2,3-c>pyridazine-2-carboxylate

: 141238-75-7
3,4-diphenyl-11-oxo-10,11-dihydro-12H-pyridazino<4',3':4,5>pyrrolo<3,2-b>benzoxazepine

Conditions

Conditions	Yield
In acetic acid for 5h; Heating;	50%

: 142-71-2
copper diacetate

: 51-19-4
2-aminophenol hydrochloride

: Phenylmalondialdehyd-natrium salz

: Cu3((bis[(2-mercapto)anil] of phenylmalonaldehyde)-3H)2

Conditions

Conditions	Yield
With CH3COOH In 1,4-dioxane; methanol to a mixt. of methanol solns. of sodium phenylmalonaldehyde and o-aminophenol hydrochloride was added a 1:1 methanol-dioxane mixt. to dissolve the ppt. and then soln. of Cu-contg. compd. with 2-3 drops of AcOH to supress hydrolysis; the ppt. was filtered out, washed with methanol, and dried in a vac. oven at 120°C; elem. anal.;	50%

...Expand

: 142-71-2
copper diacetate

: 34461-00-2
nitromalondialdehyde sodium salt

: 51-19-4
2-aminophenol hydrochloride

: Cu3((bis[(2-mercapto)anil] of nitromalonaldehyde)-3H)2

Conditions

Conditions	Yield
With CH3COOH In 1,4-dioxane; methanol to a mixt. of methanol solns. of sodium nitromalonaldehyde and o-aminophenol hydrochloride was added a 1:1 methanol-dioxane mixt. to dissolve the ppt. and then soln. of Cu-contg. compd. with 2-3 drops of AcOH to supress hydrolysis; the ppt. was filtered out, washed with methanol, and dried in a vac. oven at 120°C; elem. anal.;	50%

...Expand

: 7732-18-5
water

: 51-19-4
2-aminophenol hydrochloride

: 373-02-4, 14998-37-9, 33025-09-1, 94044-50-5, 98268-31-6
nickel diacetate

: Phenylmalondialdehyd-natrium salz

: Ni3((bis[(2-mercapto)anil] of phenylmalonaldehyde)-3H)2*4H2O

Conditions

Conditions	Yield
With CH3COOH; KOH In 1,4-dioxane; methanol to a mixt. of methanol solns. of sodium phenylmalonaldehyde and o-aminophenol hydrochloride was added a 1:1 methanol-dioxane mixt. to dissolve the ppt. and then soln. of Ni-contg. compd. with 2-3 drops of AcOH to supress hydrolysis; addn. of KOH in MeOH; the ppt. was filtered out, washed with methanol, and dried in a vac. oven at 120°C; elem. anal.;	50%

...Expand

: 51-19-4
2-aminophenol hydrochloride

: 57-13-6
urea

A: 59-49-4
2-Benzoxazolinone

B: 1196-72-1
n-(2-hydroxy-benzene)-urea

C: 63118-40-1
N-(o-hydroxyphenyl)biuret

Conditions

Conditions	Yield
at 175℃; for 2h;	A 49% B 1% C 0.4%

...Expand

: 3-phenyl-2-(3-phenoxyphenyl)acrylonitrile

: 51-19-4
2-aminophenol hydrochloride

: 2-[2-phenyl-1-(3-phenoxyphenyl)vinyl]benzoxazole

Conditions

Conditions	Yield
at 220 - 250℃; for 10h; Sealed tube;	36%

2-Aminophenol hydrochloride Chemical Properties

Molecular formula ：C₆H₇NO
Molar mass ：109.13 g/mol
Appearance ：White orthorhombic pyramidal needles
Density ：1.328 g/cm3
Melting point ：174 °C
Solubility in WATER：slightly soluble in cold WATER, soluble in hot WATER

2-Aminophenol hydrochloride Uses

it is an amphoteric molecule and a reducing agent.

2-Aminophenol hydrochloride Production

It is industrially synthesized by reducing the corresponding nitrophenol by hydrogen in the presence of various catalysts.

2-Aminophenol hydrochloride Toxicity Data With Reference

RTECS SJ6069000

Product Name

2-AMINOPHENOL HYDROCHLORIDE

Synthetic route

2-Aminophenol hydrochloride Chemical Properties

2-Aminophenol hydrochloride Uses

2-Aminophenol hydrochloride Production

2-Aminophenol hydrochloride Toxicity Data With Reference

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