2-Aminophenol supplier | CasNO.95-55-6

Name
2-Aminophenol
EINECS 202-431-1
CAS No. 95-55-6
Article Data366
CAS DataBase
Density 1.211 g/cm³
Solubility 17 g/L (20 °C) in water
Melting Point 172 °C
Formula C₆H₇NO
Boiling Point 234.496 °C at 760 mmHg
Molecular Weight 109.128
Flash Point 95.62 °C
Transport Information UN 2512 6.1/PG 3
Appearance Colorless to light yellow liquid
Safety 28-36/37-28A-45-36/37/39-26
Risk Codes 20/22-68-34-20/21/22
Molecular Structure
Hazard Symbols Xn, C
Synonyms NakoYellow 3GA;Paradone Olive Green B;Pelagol 3GA;Pelagol Grey GG;Rodol 2G;Zoba 3GA;o-Aminohydroxybenzene;o-Aminophenol;o-Hydroxyaniline;o-Hydroxyphenylamine;o-aminophenol;o-hydroxyaniline;O-Amino phenol;Phenol,o-amino- (8CI);(2-Hydroxyphenyl)amine;1-Amino-2-hydroxybenzene;1-Hydroxy-2-aminobenzene;2-Amino-1-hydroxybenzene;Phenol,2-amino-;2-Aminophenylalcohol;2-Hydroxyaniline;2-Hydroxybenzenamine;BASF Ursol 3GA;Benzofur GG;C.I. 76520;C.I. Oxidation Base 17;Fouramine OP;NSC 1534;NSC 226261;
PSA 46.25000
LogP 1.55560

Synthetic route

: 88-75-5
2-hydroxynitrobenzene

: 95-55-6
2-amino-phenol

Conditions

Conditions	Yield
With hydrogen; Pd in AV-17-8-Pd In ethanol at 40℃;	100%
With hydrogen; Pd in AV-17-8-Pd In ethanol at 40℃; under 760 Torr; Rate constant;	100%
With hydrogen; palladium-containing anion exchanger AB-17-8-Pd In ethanol at 20 - 40℃; under 750.06 Torr; Kinetics; Product distribution; Further Variations:; Catalysts;	100%

: 59-49-4
2-Benzoxazolinone

: 95-55-6
2-amino-phenol

Conditions

Conditions	Yield
With ammonium bromide; ethylenediamine at 70℃; for 2h; Microwave irradiation;	99%
In 1,2-dichloro-ethane at 95 - 105℃; under 0 - 1125.11 Torr; Alkaline conditions; Large scale;	96.5%
With sodium hydroxide In water at 100℃; for 16h;	72%
Alkaline hydrolysis;

: 533-58-4
2-Iodophenol

: 95-55-6
2-amino-phenol

Conditions

Conditions	Yield
With [Cu2(2,7-bis(pyridin-2-yl)-l,8-naphthyridine)(OH)(CF3COO)3]; tetrabutylammomium bromide; ammonia; caesium carbonate In water at 110 - 120℃; for 16h; Sealed tube;	99%
With ammonium hydroxide In water at 20℃; for 9h; Green chemistry;	96%

: 5570-18-3
2-aminophenylboronic acid

: 95-55-6
2-amino-phenol

Conditions

Conditions	Yield
With dihydrogen peroxide In neat (no solvent) at 30℃; for 0.3h; Green chemistry;	90%
With water; oxygen; sodium sulfite at 50℃; for 2h; Green chemistry;	72%

: 36309-44-1
2-((trimethylsilyl)oxy)aniline

: 95-55-6
2-amino-phenol

Conditions

Conditions	Yield
With methanol; 1,3-disulfonic acid imidazolium hydrogen sulfate at 20℃; for 0.0833333h; Green chemistry;	98%
With rice husk ash supported on anatase-phase titania nanoparticles nanocomposite In methanol at 20℃; for 0.05h;	94%
With nano magnetic sulfated zirconia (Fe3O4 at ZrO2/SO42-) In neat (no solvent) at 20℃; for 0.333333h; Green chemistry;	90%

: 95-56-7
2-hydroxybromobenzene

: 95-55-6
2-amino-phenol

Conditions

Conditions	Yield
With ammonium hydroxide In water at 20℃; for 9h; Green chemistry;	93%
With ammonium hydroxide; L-2-O-methyl-chiro-inositol; copper(II) acetate monohydrate; potassium iodide In 1-methyl-pyrrolidin-2-one at 150℃; for 12h;	70%
With ammonium hydroxide; copper at 80℃; for 7h; Inert atmosphere;	65.5%

: 108-95-2
phenol

: 95-55-6
2-amino-phenol

Conditions

Conditions	Yield
Stage #1: phenol With copper(ll) sulfate pentahydrate; copper In water at 30℃; for 2h; Inert atmosphere; Sealed tube; Stage #2: With ammonium hydroxide; sodium hydroxide In water at 20℃; for 1h; pH=~ 9; Inert atmosphere; Sealed tube;
Multi-step reaction with 2 steps 1: nitric acid; sulfuric acid / water / 2 h / 50 - 55 °C 2: iron; acetic acid / water / 0.75 h / Reflux View Scheme
Multi-step reaction with 2 steps 1: nitric acid; sulfuric acid / 1.08 h / 15 - 25 °C / 9000.9 Torr 2: hydrogenchloride; zinc / water / 1.5 h / 70 °C / 9750.98 Torr / Sealed tube View Scheme
Multi-step reaction with 2 steps 1.1: acetic acid 1.2: 12 h / 0 - 25 °C 2.1: ammonium hydroxide; copper / 7 h / 80 °C / Inert atmosphere View Scheme

: 2050-14-8
2,2'-Dihydroxyazobenzene

: 95-55-6
2-amino-phenol

Conditions

Conditions	Yield
With aminomethyl polysterene resin formic acid salt; zinc In methanol at 20℃; for 0.3h;	96%
With polystyrene-CH2-NH3(+)HCO2(-); magnesium In methanol at 20℃; for 0.266667h;	96%
With aminomethylpolystyrene-supported formate; palladium on activated charcoal In methanol at 20℃; for 3.5h;	95%

: 273-53-0
benzoxazole

: 95-55-6
2-amino-phenol

Conditions

Conditions	Yield
With trifluoroacetic acid In isopropyl alcohol at 70℃; for 18h;	67%
With bis(triphenylphosphine)copper(I) cyanide; caesium carbonate; triphenylphosphine Reagent/catalyst;	62%
With ethylene glycol; zinc(II) chloride In neat (no solvent) at 120℃; for 6h; Green chemistry;	62%

: 2382-96-9
benzo[d]oxazole-2-(3H)-thione

: 95-55-6
2-amino-phenol

Conditions

Conditions	Yield
With 3-azapentane-1,5-diamine at 130℃; for 2h; Sealed tube;	98%
With ammonium bromide; ethylenediamine at 80℃; for 5h; Microwave irradiation;	91%

: 24541-44-4
2-azidophenol

: 95-55-6
2-amino-phenol

Conditions

Conditions	Yield
With hydrazinium monoformate; zinc In methanol at 20℃; for 0.166667h;	96%
With zinc In methanol at 20℃; for 4h;	96%
With aluminium(III) iodide In benzene for 0.25h; Reduction; Heating;	95%
With ammonium formate; zinc In methanol at 20℃; for 0.3h;	85%

: 615-43-0
2-iodophenylamine

: 95-55-6
2-amino-phenol

Conditions

Conditions	Yield
Stage #1: 2-iodophenylamine With copper(l) iodide; 8-Hydroxyquinoline-N-oxide In dimethyl sulfoxide at 20℃; for 0.166667h; Inert atmosphere; Stage #2: With cesiumhydroxide monohydrate In water; dimethyl sulfoxide at 100℃; for 36h; Inert atmosphere;	84%
With copper(l) iodide; lithium pipecolinate; tetrabutyl ammonium fluoride; sodium hydroxide In water at 130℃; for 24h;	74%

: 90-04-0
2-methoxy-phenylamine

: 95-55-6
2-amino-phenol

Conditions

Conditions	Yield
With 1-methyl-pyrrolidin-2-one; potassium carbonate at 190℃; for 0.5h;	80%
With 1-methyl-pyrrolidin-2-one; potassium carbonate; thiophenol for 0.5h; Heating;	80%
With water; hydrogen bromide; Aliquat 336 at 105℃; for 6.5h; Catalytic behavior;	72%
With aluminium trichloride In various solvent(s) for 0.5h; Heating;
With aluminium trichloride

: 88-75-5
2-hydroxynitrobenzene

A: 3009-34-5
quinoneimine

B: 95-55-6
2-amino-phenol

Conditions

Conditions	Yield
With potassium fluoride; polymethylhydrosiloxane; palladium diacetate In tetrahydrofuran at 20℃; for 0.5h;	A 4% B 94%

: 273-53-0
benzoxazole

: 103-67-3
benzyl-methyl-amine

A: N-benzyl-N-methylbenzo[d]oxazol-2-amine

B: 95-55-6
2-amino-phenol

Conditions

Conditions	Yield
With dipotassium peroxodisulfate; acetic acid; triphenylphosphine; copper(ll) bromide In water at 40℃; for 6h;	A 15% B n/a

...Expand

: 95-57-8
2-monochlorophenol

: 95-55-6
2-amino-phenol

Conditions

Conditions	Yield
With ammonium hydroxide; potassium phosphate; Cu0.18Bi0.88O0.88I1.06 In ethanol; water at 80℃; for 20h; Inert atmosphere; Green chemistry;	76 %Chromat.

: 88-75-5
2-hydroxynitrobenzene

: 100-51-6
benzyl alcohol

A: 95-55-6
2-amino-phenol

B: 65-85-0
benzoic acid

Conditions

Conditions	Yield
With potassium hydroxide In 1,3,5-trimethyl-benzene at 160℃; for 24h; Inert atmosphere; Overall yield = 85 percent;

...Expand

1-azido-2-(Wang resin-CH2O)-benzene: 1-azido-2-(Wang resin-CH2O)-benzene

: 95-55-6
2-amino-phenol

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate; ethanethiol In dichloromethane at 20℃; for 2h;	90%

: 121555-67-7
2,6-Dichloro-3,5-difluoro-4-nitro-phenol

A: 2,6-Dichloro-3,5-difluoro-4-amino-phenol

B: 95-55-6
2-amino-phenol

Conditions

Conditions	Yield
With hydrogen In methanol; aluminum nickel
With hydrogen In methanol; aluminum nickel
With hydrogen In methanol; aluminum nickel

: 62-53-3
aniline

A: 123-30-8
4-amino-phenol

B: 95-55-6
2-amino-phenol

Conditions

Conditions	Yield
With hydrogenchloride; sodium acetate; hemin; rac-cysteine In water; acetone at 40℃; for 2h; Mechanism; pH=3; pH and reaction time dependency, various catalysts and inhibitors;
With dihydrogen peroxide; FePp In ethanol at 38℃; for 0.166667h; Product distribution; borate buffer, pH 9; further educts;
With oxygen; titanium(IV) oxide In water at 26.84℃; for 1.5h; pH=6.5; Irradiation; Title compound not separated from byproducts.;
With dihydrogen peroxide; bis(triphenyl)oxodiphosphonium trifluoromethanesulfonate salt In ethanol; water at 20℃; for 0.666667h; Overall yield = 80 %; Overall yield = 0.087 g;

: 69589-21-5
2-((tert-butyldimethylsilyl)oxy)aniline

: 95-55-6
2-amino-phenol

Conditions

Conditions	Yield
With tin(ll) chloride In ethanol at 20℃; for 5h;	88%

: 116296-18-5
(E)-2-(phenyldiazenyl)phenyl benzoate

A: 93-98-1
N-phenyl benzoyl amide

B: 95-55-6
2-amino-phenol

Conditions

Conditions	Yield
With ammonium chloride; zinc In methanol at 80℃; for 6h; Inert atmosphere;	A 71% B 64%

: 91-23-6
2-Nitroanisole

: 95-55-6
2-amino-phenol

Conditions

Conditions	Yield
With 1,3-dimethyl-2-imidazolidinone; sodium trimethylsilanethiolate at 185℃; for 24h;	96%

: 121555-68-8
2-chloro-3,5,6-trifluoro-4-nitrophenol

A: 2-Chloro-3,5,6-trifluoro-4-amino-phenol

B: 95-55-6
2-amino-phenol

Conditions

Conditions	Yield
aluminum nickel In methanol

: 107-21-1
ethylene glycol

: 108-95-2
phenol

: 95-55-6
2-amino-phenol

Conditions

Conditions	Yield
With hydrogenchloride; paraformaldehyde In water

: 127-17-3
2-oxo-propionic acid

: 88-75-5
2-hydroxynitrobenzene

A: 84529-13-5
3-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-one

B: 95-55-6
2-amino-phenol

Conditions

Conditions	Yield
With palladium 10% on activated carbon; hydrogen In water; isopropyl alcohol at 30℃; under 7500.75 Torr; for 10h; Autoclave;	A 28% B n/a

...Expand

: 89466-08-0
2-hydroxyphenyl boronic acid

: 95-55-6
2-amino-phenol

Conditions

Conditions	Yield
With sodium hydroxide; hydroxylamine-O-sulfonic acid In acetonitrile at 20℃; for 16h;	80%

: (E)-1-(2-hydroxyphenyl)-3-(3-(thiophen-2-yl)acryloyl)thiourea

A: 1124-65-8, 15690-25-2, 51019-83-1
3-(2-thienyl)-2-propenoic acid

B: 95-55-6
2-amino-phenol

Conditions

Conditions	Yield
With sodium hydroxide In ethanol for 1h; Reflux;

: 2-(pyrimidin-2-ylamino)phenyl 4-chlorobenzoate

: 95-55-6
2-amino-phenol

Conditions

Conditions	Yield
With hydrogenchloride In water at 150℃; for 3h; Microwave irradiation; Sealed tube;	71%

: 614-80-2
2-(acetylamino)phenol

A: 95-55-6
2-amino-phenol

B: 614-70-0
2-ethylaminophenol

Conditions

Conditions	Yield
With [bis(2-methylallyl)cycloocta-1,5-diene]ruthenium(II); formic acid; bis(trifluoromethanesulfonyl)amide; triethylamine; [2-((diphenylphospino)methyl)-2-methyl-1,3-propanediyl]bis[diphenylphosphine] In dibutyl ether at 130℃; for 24h;	A 83% B n/a

: 100-52-7
benzaldehyde

: 95-55-6
2-amino-phenol

: 833-50-1
2-phenylbenzo[d]oxazole

Conditions

Conditions	Yield
With Au NCs/TiO2 In toluene at 130℃; Inert atmosphere;	100%
With ISO-PECH polyamine catalyst In methanol at 20℃; for 0.0666667h; Green chemistry;	99%
With Co-doped NiFe2O4 nanoparticle In neat (no solvent) at 70℃; for 2h;	97%

: 95-55-6
2-amino-phenol

: 762-42-5
dimethyl acetylenedicarboxylate

: 66628-73-7
(2Z)-[2-oxo-2H-1,4-benzoxazine-3(4H)-ylidene]acetic acid methyl ester

Conditions

Conditions	Yield
at 20℃; for 0.0666667h; Michael addition;	100%
In neat (no solvent) at 20℃; for 0.166667h; regioselective reaction;	98%
In ethanol at 0℃; for 3h;	94%

: 100-52-7
benzaldehyde

: 95-55-6
2-amino-phenol

: 3230-45-3
(E)-N-benzylidene-2-hydroxyaniline

Conditions

Conditions	Yield
With magnesium sulfate In tetrahydrofuran at 0 - 20℃; for 8h;	100%
In ethanol at 25℃; for 24h;	91%
In ethanol for 2h; Reflux;	85%

: 120-14-9
3,4-dimethoxy-benzaldehyde

: 95-55-6
2-amino-phenol

: 80241-83-4
2-(3,4-dimethoxyphenylmethyleneimino)phenol

Conditions

Conditions	Yield
In toluene Heating;	100%
In ethanol for 3h; Reflux;	75%

: 75-77-4
chloro-trimethyl-silane

: 95-55-6
2-amino-phenol

: 36309-44-1
2-((trimethylsilyl)oxy)aniline

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 27℃; for 24h; Inert atmosphere; Glovebox;	100%
With triethylamine In dichloromethane at 20℃; for 18h;	80.5%
	76%

: 73568-25-9
2-chloro-3-quinoline carboxaldehyde

: 95-55-6
2-amino-phenol

: 112697-88-8
2-((2-chloroquinolin-3-yl)methyleneamino)phenol

Conditions

Conditions	Yield
In tetrahydrofuran for 2h; Ambient temperature;	100%
In ethanol at 20℃; for 0.333333h; Sonication;	78%
With acetic acid In ethanol at 20℃;

: 1066-35-9
dimethylmonochlorosilane

: 95-55-6
2-amino-phenol

: 18245-89-1
2,2-dimethyl-2,3-dihydro-benzo[1,3,2]oxazasilole

Conditions

Conditions	Yield
With triethylamine In tetrahydrofuran for 6h; Heating;	100%

: 1118-02-1
trimethylsilyl isocyanate

: 95-55-6
2-amino-phenol

: 75226-86-7
(2-Trimethylsilanyloxy-phenyl)-urea

Conditions

Conditions	Yield
In tetrahydrofuran at 60 - 65℃; for 5h;	100%

: 95-55-6
2-amino-phenol

: 999-97-3
1,1,1,3,3,3-hexamethyl-disilazane

: 36309-44-1
2-((trimethylsilyl)oxy)aniline

Conditions

Conditions	Yield
With 1,3-disulfonic acid imidazolium hydrogen sulfate In neat (no solvent) at 20℃; for 0.0166667h; Green chemistry;	100%
With poly(4-vinylpyridine) In acetonitrile at 20℃; for 0.5h; chemoselective reaction;	98%
With 3-methyl-1-sulfonic acid imidazolium hydrogen sulfate at 20℃; for 0.0833333h; Neat (no solvent); chemoselective reaction;	95%

: 95-55-6
2-amino-phenol

: 2258-42-6
Acetic formic anhydride

: 2843-27-8
N-(2-hydroxyphenyl)formamide

Conditions

Conditions	Yield
In tetrahydrofuran at -20℃; for 0.25h;	100%

: 95-55-6
2-amino-phenol

: 161868-74-2
1,1-dichloro-5-aza-2,8-dioxa-1-phosphaV-dibenzo<9,9',11,11'-tetra-tert-butyl>-bicyclo<3.3.0>octadiene

: C34H45N2O3P

Conditions

Conditions	Yield
In benzene for 24h; Ambient temperature;	100%

: 13154-24-0
triisopropylsilyl chloride

: 95-55-6
2-amino-phenol

: 194869-04-0
2-((triisopropylsilyl)oxy)aniline

Conditions

Conditions	Yield
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 14h; Inert atmosphere;	100%
With 1H-imidazole In dichloromethane at 20℃; for 20h;	99%
With 1H-imidazole In dichloromethane for 33h; Ambient temperature;	84%
With 1H-imidazole; triethylamine In dichloromethane at 20℃; Inert atmosphere;

: 24424-99-5
di-tert-butyl dicarbonate

: 95-55-6
2-amino-phenol

: 186663-74-1
tert-butyl (2-hydroxyphenyl)carbamate

Conditions

Conditions	Yield
copper(II) bis(tetrafluoroborate) at 30 - 33℃; for 1h;	100%
In dichloromethane at 23℃; for 22h; Inert atmosphere;	100%
With Amberlyst-15 In ethanol at 20℃;	100%

: 79099-07-3
N-tert-butyloxycarbonylpiperidin-4-one

: 95-55-6
2-amino-phenol

: 162045-48-9
1-(tert-butoxycarbonyl)-4-[(2-hydroxyphenyl)amino]piperidine

Conditions

Conditions	Yield
	100%
Stage #1: N-tert-butyloxycarbonylpiperidin-4-one; 2-amino-phenol With sodium tris(acetoxy)borohydride In 1,2-dichloro-ethane at 120℃; for 0.0833333h; Microwave irradiation; Stage #2: With water; sodium hydrogencarbonate	75%
With sodium tris(acetoxy)borohydride

: 1122-91-4
4-bromo-benzaldehyde

: 95-55-6
2-amino-phenol

: 117649-27-1, 3230-46-4
2-(4-bromo-benzylidenamino)-phenol

Conditions

Conditions	Yield
In methanol at 20℃; for 1h;	100%
In methanol at 20℃; for 1h;	100%
In ethanol Heating;	96%

: 95-55-6
2-amino-phenol

: 1-bromo-2-[4-(N-piperidinosulfonyl)phenyl]ethanedione 1-phenylhydrazone

: 2-phenylhydrazono-3-[4-(N-piperidinosulfonyl)phenyl]-1,4-benzoxazine

Conditions

Conditions	Yield
With triethylamine In ethanol for 2h; Cyclization; Heating;	100%

: 121-34-6
3-methoxy-4-hydroxybenzoic acid

: 95-55-6
2-amino-phenol

: 3164-07-6
4-(benzo[d]oxazol-2ʹ-yl)-2-methoxyphenol

Conditions

Conditions	Yield
With trimethylsilylphosphate at 180℃; for 0.5h;	100%
With Trimethylsilyl polyphosphate at 180℃; for 16.75h; Cooling with ice;	10.63 g

: 87808-44-4
3-methoxy-4-methylbenzoyl chloride

: 95-55-6
2-amino-phenol

: 669091-09-2
N-(2-hydroxyphenyl)-3-methoxy-4-methylbenzamide

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 0 - 20℃;	100%

: 40996-91-6
3-vinyl-cyclohex-2-enone

: 95-55-6
2-amino-phenol

: 906078-77-1
3-[2-(2-aminophenylsulfanyl)ethyl]cyclohex-2-enone

Conditions

Conditions	Yield
With triethylamine In benzene at 0 - 25℃; for 7h;	100%

: 112440-47-8
1,2-bis(2,4,5-trimethylthiophene-3-yl)maleic anhydride

: 95-55-6
2-amino-phenol

: 155876-10-1
N-(2-hydroxyphenyl)-2,3-bis(2,4,5-trimethyl-3-thienyl)maleimide

Conditions

Conditions	Yield
With triethylamine In toluene for 24h; Heating;	100%

: 1121-60-4
pyridine-2-carbaldehyde

: 95-55-6
2-amino-phenol

: (E)-2-((pyridin-2-yl)methyleneamino)phenol

Conditions

Conditions	Yield
acetic acid In ethanol for 12h;	100%
With air In methanol at 60℃; for 1h;	90.9%
In methanol at 20℃;	87%

: 95-55-6
2-amino-phenol

: 4-amino-3-nitrophenylimidic acid ethyl ester hydrochloride

: 132064-15-4
4-(benzo[d]oxazol-2-yl)-2-nitrobenzeneamine

Conditions

Conditions	Yield
In ethanol at 95℃; for 5h;	100%

: 1022157-41-0
ethyl 2-chloro-6-(2-methoxyphenylamino)-5-nitropyrimidine-4-carboxylate

: 95-55-6
2-amino-phenol

: 1022157-68-1
ethyl 2-(2-hydroxyphenylamino)-6-(2-methoxyphenylamino)-5-nitropyrimidine-4-carboxylate

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃;	100%

: C17H21NO4

: 95-55-6
2-amino-phenol

: C23H26N2O4

Conditions

Conditions	Yield
Stage #1: C17H21NO4 With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dimethyl sulfoxide at 20℃; for 18h; Stage #2: 2-amino-phenol In dimethyl sulfoxide; N,N-dimethyl-formamide at 20℃; for 3h;	100%

: 136-77-6
4-Hexylresorcinol

: 95-55-6
2-amino-phenol

: 18102-12-0
5-N-hexyl-2,2',4-trihydroxyazobenzene

Conditions

Conditions	Yield
Stage #1: 2-amino-phenol With hydrogenchloride; sodium nitrite In water at 5℃; for 0.166667h; Stage #2: 4-Hexylresorcinol With sodium hydroxide In water at 5℃; Cooling with ice; Stage #3: With hydrogenchloride In water	100%

: 95-55-6
2-amino-phenol

: 762-21-0
acetylenedicarboxylic acid diethyl ester

: 942199-20-4
(2Z)-[2-oxo-2H-1,4-benzoxazine-3(4H)-ylidene]acetic acid ethyl ester

Conditions

Conditions	Yield
at 20℃; for 0.0833333h; Michael addition;	100%
at 20℃; for 0.0833333h;
With sodium chloride Milling;	> 95 %Chromat.

: 1445-73-4
1-Methyl-4-piperidone

: 10349-38-9
p-methoxyphenylisocyanide

: 95-55-6
2-amino-phenol

: 1572383-01-7
2-(4-(benzo[d]oxazol-2-yl)-1-methylpiperidin-4-ylamino)phenol

Conditions

Conditions	Yield
With trifluorormethanesulfonic acid In 2,2,2-trifluoroethanol at 55℃; for 24h; Reagent/catalyst; Solvent; Temperature; Inert atmosphere;	100%

...Expand

: 100-52-7
benzaldehyde

: 98-95-3
nitrobenzene

: 95-55-6
2-amino-phenol

A: 833-50-1
2-phenylbenzo[d]oxazole

B: 538-51-2
benzylidene phenylamine

Conditions

Conditions	Yield
With Au NCs/TiO2 In toluene at 130℃; Inert atmosphere;	A 100% B 28%

...Expand

: 79354-30-6
2-(2,4,6-trimethylphenylamino)-2-oxoacetic acid ethyl ester

: 95-55-6
2-amino-phenol

: 724794-61-0
N-2-hydroxyphenyl-N'-mesityloxalamide

Conditions

Conditions	Yield
With triethylamine In toluene Reflux;	100%
With boric acid for 1h; Heating;	70%

2-Aminophenol Specification

2-Aminophenol is an organic compound with the formula C₆H₄(OH)NH₂. Along with its isomer 4-aminophenol, it is an amphoteric molecule and a reducing agent. It is a useful reagent for the synthesis of dyes and heterocyclic compounds. Reflecting its slight hydrophilic character, white powder is moderately soluble in alcohols and can be recrystallised from hot water. O-Aminophenol should avoid the condition like incompatible materials,light. It is incompatibilities with other materials light, acids, acid chlorides, acid anhydrides, chloroformates. Its hazardous decomposition products are nitrogen oxides, carbon monoxide, carbon dioxide. Its hazardous polymerization has not been reported.

Physical properties about 2-Aminophenol are: (1)ACD/LogP: 0.497; (2)ACD/LogD (pH 5.5): 0.43; (3)ACD/LogD (pH 7.4): 0.49; (4)ACD/BCF (pH 5.5): 1.21; (5)ACD/BCF (pH 7.4): 1.39; (6)ACD/KOC (pH 5.5): 38.36; (7)ACD/KOC (pH 7.4): 44.05; (8)#H bond acceptors: 2; (9)#H bond donors: 3; (10)#Freely Rotating Bonds: 2; (11)Index of Refraction: 1.637; (12)Molar Refractivity: 32.371 cm³; (13)Molar Volume: 90.144 cm³; (14)Polarizability: 12.833 10-24cm³; (15)Surface Tension: 57.4010009765625 dyne/cm; (16)Density: 1.211 g/cm³; (17)Flash Point: 95.62 °C; (18)Enthalpy of Vaporization: 49.037 kJ/mol; (19)Boiling Point: 234.496 °C at 760 mmHg; (20)Vapour Pressure: 0.0350000001490116 mmHg at 25°C

Uses of 2-Aminophenol: 2-Aminophenol has a variety of uses. As a reducing agent, it is marketed under the names of Atomal and Ortol to develop black and white photographs. 2-Aminophenol is an intermediate in the synthesis of dyes. It is particularly useful in yielding tridentate ligands for metal-complex dyes when diazotized and coupled to a phenol, naphthol, or other aromatic or resonant dye species. Metal complex dyes using copper or chromium are commonly used for producing dull colors. Tridentate ligand dyes are particularly useful, since they are more stable than their bi- or mono-dentate counterparts.

When you are using this chemical, please be cautious about it as the following:
1. After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer);
2. Wear suitable protective clothing and gloves;
3. In case of accident or if you feel unwell, seek medical advice immediately (show label where possible);
4. Wear suitable protective clothing, gloves and eye/face protection;
5. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice;

You can still convert the following datas into molecular structure:
(1)InChI=1S/C6H7NO/c7-5-3-1-2-4-6(5)8/h1-4,8H,7H2;
(2)InChIKey=CDAWCLOXVUBKRW-UHFFFAOYSA-N;
(3)Smilesc1(c(cccc1)O)N;

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LDLo	subcutaneous	37mg/kg (37mg/kg)	LUNGS, THORAX, OR RESPIRATION: CYANOSIS LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: GENERAL ANESTHETIC	Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 72, Pg. 241, 1913.
guinea pig	LD50	skin	> 1gm/kg (1000mg/kg)		National Technical Information Service. Vol. OTS0555965,
mouse	LD50	intraperitoneal	200mg/kg (200mg/kg)		National Technical Information Service. Vol. AD691-490,
mouse	LD50	oral	800mg/kg (800mg/kg)	LUNGS, THORAX, OR RESPIRATION: CYANOSIS BEHAVIORAL: TREMOR	National Technical Information Service. Vol. OTS0555965,
mouse	LD50	unreported	675mg/kg (675mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 50(3), Pg. 4, 1985.
quail	LD50	oral	316mg/kg (316mg/kg)		Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.
rat	LD50	oral	951mg/kg (951mg/kg)	BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: CYANOSIS	National Technical Information Service. Vol. OTS0555965,
rat	LD50	subcutaneous	37mg/kg (37mg/kg)		Yakkyoku. Pharmacy. Vol. 32, Pg. 1093, 1981.
rat	LD50	unreported	1406mg/kg (1406mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 50(3), Pg. 4, 1985.
rat	LDLo	intraperitoneal	300mg/kg (300mg/kg)		Archives Internationales de Pharmacodynamie et de Therapie. Vol. 131, Pg. 151, 1961.

Product Name

2-Aminophenol

Synthetic route

2-Aminophenol Specification

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