2-Methoxyethyl acrylate supplier

Name
2-Methoxyethyl acrylate
EINECS 221-499-3
CAS No. 3121-61-7
Article Data6
CAS DataBase
Density 1.012
Solubility 144g/L at 20℃
Melting Point -30°C
Formula C6H10 O3
Boiling Point 56 ºC (12 mmHg)
Molecular Weight 130.144
Flash Point 60 ºC
Transport Information UN 1992
Appearance Clear colorless liquid with a sharp musty odor.
Safety Poison by skin contact. Moderately toxic by ingestion and inhalation. Experimental reproductive effects. A skin irritant. Flammable when exposed to heat or flame; can react with oxidizing materials. To fight fire, use foam, CO₂, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes. See also GLYCOL ETHERS.
Risk Codes R20/22;R24;R60;R61
Molecular Structure
Hazard Symbols
Synonyms Acrylicacid, 2-methoxyethyl ester (6CI,7CI,8CI); 2-Methoxyethyl acrylate; 2MTA; DC 1;DC 1 (acrylate); Ethylene glycol monomethyl ether acrylate; Methoxyethylacrylate; NSC 24153; SR 244; Viscoat 2MTA
PSA 35.53000
LogP 0.36200

Synthetic route

: 109-86-4
2-methoxy-ethanol

: 292638-85-8
acrylic acid methyl ester

: 3121-61-7
2-methoxyethyl acrylate

Conditions

Conditions	Yield
With 4-acetylamino-2,2,6,6-tetramethyl-1-piperidinoxy; di(n-butyl)tin oxide In 2-Methylpentane; cyclohexane at 85 - 100℃; for 12h; Temperature; Solvent;	95%
With copper; toluene-4-sulfonic acid; hydroquinone Abdestillieren des entstandenen Methanols als Azeotrop mit Methylacrylat;

: 109-86-4
2-methoxy-ethanol

: 140-88-5
ethyl acrylate

: 3121-61-7
2-methoxyethyl acrylate

Conditions

Conditions	Yield
With copper; toluene-4-sulfonic acid; hydroquinone Abdestillieren des entstandenen Aethanols als Azeotrop mit Aethylacrylat;

: 109-86-4
2-methoxy-ethanol

: 814-68-6
acryloyl chloride

: 3121-61-7
2-methoxyethyl acrylate

Conditions

Conditions	Yield
With triethylamine In chloroform at 10℃; for 12h;
In dichloromethane

: 3121-61-7
2-methoxyethyl acrylate

: 31020-47-0
bis((methyldiethoxysilyl)propyl)amine

: 2-methoxyethyl 3-(bis(3-diethoxymethylsilylpropyl)amino)propanoate

Conditions

Conditions	Yield
In ethanol at 20℃; for 8h; Inert atmosphere;	98.327%

: 3121-61-7
2-methoxyethyl acrylate

: 13497-18-2
bis-(3-triethoxysilylpropyl)amine

: 2-methoxyethyl 3-(bis(3-triethoxysilylpropyl)amino)propanoate

Conditions

Conditions	Yield
In ethanol at 20℃; for 8h; Inert atmosphere;	97.3%

: 3121-61-7
2-methoxyethyl acrylate

: 108-98-5
thiophenol

: 3-phenylsulfanyl-propionic acid butyl ester

Conditions

Conditions	Yield
With scandium tris(trifluoromethanesulfonate) In neat (no solvent) at 20℃; for 2h; Green chemistry; regioselective reaction;	97%

: (N-cyclohexylaminomethyl)triethoxysilane

: 3121-61-7
2-methoxyethyl acrylate

: 2-methoxyethyl 3-(cyclohexyl((triethoxysilyl)methyl)amino)propanoate

Conditions

Conditions	Yield
In ethanol at 20℃; for 8h; Inert atmosphere;	96.7%

: 3121-61-7
2-methoxyethyl acrylate

: 618-40-6
1-Methyl-1-phenylhydrazine

: (E)-2-methoxyethyl 3-(2-(methylamino)phenyl)acrylate

Conditions

Conditions	Yield
With [RhCl2(p-cymene)]2; potassium acetate In methanol at 70℃; Sealed tube;	96%
With silver hexafluoroantimonate; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; acetic acid In methanol at 25℃; for 6h;	91%

: 64-17-5
ethanol

: 3121-61-7
2-methoxyethyl acrylate

: 120-46-7
1,3-diphenylpropanedione

: 73172-56-2
ethyl 4-benzoylbutanoate

Conditions

Conditions	Yield
With potassium carbonate at 85℃; Sealed tube;	95%

...Expand

: 3121-61-7
2-methoxyethyl acrylate

: 945761-25-1
1-iodosinomenine

: C25H31NO7

Conditions

Conditions	Yield
With palladium diacetate; triethylamine; triphenylphosphine In N,N-dimethyl-formamide at 85℃; for 0.333333h; Time; Heck Reaction;	93%

: 3121-61-7
2-methoxyethyl acrylate

: 501-65-5
diphenyl acetylene

: 1644664-66-3
2-methoxyethyl (2E,4Z)-4,5-diphenylpenta-2,4-dienoate

Conditions

Conditions	Yield
With C34H32N2Ru In toluene at 20 - 22℃; for 24h; Inert atmosphere;	93%

: 3121-61-7
2-methoxyethyl acrylate

: (1E,4E)-1,5-di-p-tolylpenta-1,4-dien-3-one O-isopropyl oxime

: 2-methoxyethyl (E)-6-(4-methylstyryl)-4-(p-tolyl)picolinate

Conditions

Conditions	Yield
With palladium diacetate; silver trifluoroacetate; 2,6-bis(((3S,5S,7S)-adamantan-1-yl)oxy)pyridine In 1,4-dioxane at 90℃; for 24h; regioselective reaction;	93%

: 931-40-8
4-hydroxymethyl-1,3-dioxolan-2-one

: 3121-61-7
2-methoxyethyl acrylate

: 7528-90-7
acrylic acid 2-oxo-[1,3]dioxolan-4-ylmethyl ester

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane; zinc diacrylate; oxygen; 4-methoxy-phenol at 105 - 120℃; under 90 - 760 Torr; for 20h; Catalytic behavior; Reagent/catalyst; Pressure;	92%

: 3121-61-7
2-methoxyethyl acrylate

: 363-72-4
Pentafluorobenzene

: 1226635-89-7
C12H11F5O3

Conditions

Conditions	Yield
With [Rh(OH)(cod)]2; o-phenylenebis(diphenylphosphine); water In 1,4-dioxane at 120℃; for 24h; Inert atmosphere;	91%

: 98-01-1
furfural

: 3121-61-7
2-methoxyethyl acrylate

: 144261-84-7
3-(2-furyl)-3-hydroxy-2-methylene-propanoic acid 2-methoxyethyl ester

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane for 36h; Ambient temperature;	90%

: 491-38-3
1-benzopyran-4(4H)-one

: 3121-61-7
2-methoxyethyl acrylate

: (E)-methoxyethyl 3-(4-oxo-4H-chromen-5-yl)acrylate

Conditions

Conditions	Yield
With [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; silver(I) acetate; silver(I) triflimide In 1,2-dichloro-ethane at 20 - 120℃; for 1h; Sealed tube;	90%

: 3121-61-7
2-methoxyethyl acrylate

: 100-52-7
benzaldehyde

: 144261-74-5
3-phenyl-3-hydroxy-2-methylene-propanoic acid 2-methoxyethyl ester

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane for 96h; Ambient temperature;	89%

: 1070-83-3
tert-Butylacetic acid

: 3121-61-7
2-methoxyethyl acrylate

: 2-methoxyethyl 2-(4,4-dimethyl-6-oxotetrahydro-2H-pyran-2-yl)acetate

Conditions

Conditions	Yield
With disodium phosphate heptahydrate; (S)-2-acetylamino-3-phenylpropanoic acid; palladium diacetate; silver carbonate at 120℃; for 18h; Sealed tube;	88%

: 948-65-2
2-phenyl-indole

: 3121-61-7
2-methoxyethyl acrylate

: (2E,2'E)-bis(2-methoxyethyl) 3,3'-(2-(1H-indol-2-yl)-1,3-phenylene)diacrylate

Conditions

Conditions	Yield
With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; copper diacetate In ethyl acetate at 140℃; for 24h; Inert atmosphere; Schlenk technique; regioselective reaction;	86%

: 3121-61-7
2-methoxyethyl acrylate

: 5908-41-8
benzoyltrimethylsilane

: 2-methoxyethyl (E)-3-(2-((trimethylsilyl)carbonyl)phenyl)acrylate

Conditions

Conditions	Yield
With silver hexafluoroantimonate; [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; copper diacetate In 1,2-dichloro-ethane at 60℃; for 24h; Sealed tube; Inert atmosphere; Enzymatic reaction;	86%

: 3121-61-7
2-methoxyethyl acrylate

: 108-98-5
thiophenol

: 2-methoxyethyl 3-(phenylthio)propionate

Conditions

Conditions	Yield
With scandium tris(trifluoromethanesulfonate) In neat (no solvent) at 20℃; for 3h; Green chemistry; regioselective reaction;	85%

: 874-14-6
1,3-dimethyluracil

: 3121-61-7
2-methoxyethyl acrylate

: (E)-2-methoxyethyl 3-(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylate

Conditions

Conditions	Yield
With N-Cbz-L-Phe; oxygen; palladium diacetate; Trimethylacetic acid In N,N-dimethyl acetamide at 100℃; under 760.051 Torr; for 24h; Heck Reaction; Schlenk technique; Green chemistry;	85%

: 118-90-1
ortho-methylbenzoic acid

: 3121-61-7
2-methoxyethyl acrylate

: 2-methoxyethyl 2-(4-methyl-3-oxo-1,3-dihydroisobenzofuran-1-yl)acetate

Conditions

Conditions	Yield
With [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; oxygen; potassium acetate; acetic acid at 80℃; under 760.051 Torr; for 18h; Green chemistry; chemoselective reaction;	85%
With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; potassium acetate; p-benzoquinone In tert-Amyl alcohol; water at 100℃; for 18h; Electrolysis; chemoselective reaction;	84%

: 3121-61-7
2-methoxyethyl acrylate

: 4711-95-9
1,4-butanediol monoglycidyl ether

: 119692-59-0
4-Hydroxybutyl acrylate glycidyl ether

Conditions

Conditions	Yield
With tetrabutoxytitanium; 4-methoxy-phenol In o-xylene at 80 - 90℃; under 75.0075 Torr;	83.7%

: 3121-61-7
2-methoxyethyl acrylate

: C14H27NSi2

: C20H31NO6

Conditions

Conditions	Yield
With tris(2,2'-bipyridyl)ruthenium dichloride In N,N-dimethyl-formamide at 25℃; for 12h; Schlenk technique; Sealed tube; Glovebox; Inert atmosphere; Irradiation;	83%

: 3121-61-7
2-methoxyethyl acrylate

: 1422263-07-7
2-methoxyethyl 2-iodoacrylate

Conditions

Conditions	Yield
With N-iodophthalimide; 3-quinuclidinol In acetonitrile at 20℃; for 24h; Darkness; chemoselective reaction;	82%

: 3121-61-7
2-methoxyethyl acrylate

: 120-46-7
1,3-diphenylpropanedione

: 2-methoxyethyl 5-oxo-5-phenylpentanoate

Conditions

Conditions	Yield
With potassium carbonate at 85℃; Sealed tube;	80%
With potassium carbonate In 2-methoxy-ethanol at 85℃; for 24h;	80%

: 123-75-1
pyrrolidine

: 3121-61-7
2-methoxyethyl acrylate

: 1074-12-0
phenylglyoxal hydrate

: 2-methoxyethyl 5-benzoyl-1-(2-oxo-2-phenylethyl)-2,3-dihydro-1H-pyrrolizine-7-carboxylate

Conditions

Conditions	Yield
With acetic acid In toluene at 100℃; for 0.666667h;	80%

...Expand

: 3121-61-7
2-methoxyethyl acrylate

: 108-95-2
phenol

: 2-methoxyethyl (E)-3-phenoxyacrylate

Conditions

Conditions	Yield
With tetrabutylammomium bromide; oxygen; palladium diacetate; potassium carbonate In dichloromethane at 40℃; for 36h; Schlenk technique;	80%

: 3121-61-7
2-methoxyethyl acrylate

: 2-(cyclohex-2-en-1-yloxy)-1,10-phenanthroline

: 2-methoxyethyl (E)-3-(6-((1,10-phenanthrolin-2-yl)oxy)cyclohex-1-en-1-yl)acrylate

Conditions

Conditions	Yield
With 2-methyl-2-phenylpropionic acid; palladium diacetate; silver trifluoroacetate; p-benzoquinone In acetonitrile at 50℃; under 760.051 Torr; for 22h; Sealed tube; regioselective reaction;	79%

: 544-12-7
3-hexen-1-ol

: 3121-61-7
2-methoxyethyl acrylate

: C12H20O4

Conditions

Conditions	Yield
With 2,2,2-trifluoroethanol; (S)-2-acetylamino-3-phenylpropanoic acid; palladium diacetate; caesium carbonate; silver carbonate In 1,4-dioxane at 70℃; for 16h; Inert atmosphere;	78%

: 3121-61-7
2-methoxyethyl acrylate

: 10036-43-8
α-(Fluorophenyl)acetonitrile

: 2-methoxyethyl 4-cyano-4-fluoro-4-phenylbutanoate

Conditions

Conditions	Yield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In dimethyl sulfoxide at 25℃; Catalytic behavior; Solvent; Michael Addition;	76%

2-Methoxyethyl acrylate Chemical Properties

Product Name: Methyl cellosolve acrylate (CAS NO.3121-61-7)

Molecular Formula: C₆H₁₀O₃
Molecular Weight: 130.14g/mol
Mol File: 3121-61-7.mol
Einecs: 221-499-3
Appearance: Clear colorless to slightly yellow liquid
Melting Point: -30°C
Boiling point: 151.7 °C at 760 mmHg
Flash Point: 51.8 °C
Density: 1.012 g/mL at 25 °C(lit.)
Refractive index: n20/D 1.427(lit.)
Surface Tension: 27.7 dyne/cm
Enthalpy of Vaporization: 38.85 kJ/mol
Vapour Pressure: 3.62 mmHg at 25°C
XLogP3: 0.3
H-Bond Donor: 0
H-Bond Acceptor: 3

2-Methoxyethyl acrylate Toxicity Data With Reference

1.	skn-rbt 500 mg open MLD	UCDS** Union Carbide Data Sheet. (Industrial Medicine and Toxicology Dept., Union Carbide Corp., 270 Park Ave., New York, NY 10017) 9/17 ,1969.
2.	orl-mus TDLo:5200 mg/kg (female 6-13D post):REP	TCMUD8 Teratogenesis, Carcinogenesis, and Mutagenesis. 7 (1987),29.
3.	orl-rat LD50:810 mg/kg	UCDS** Union Carbide Data Sheet. (Industrial Medicine and Toxicology Dept., Union Carbide Corp., 270 Park Ave., New York, NY 10017) 9/17 ,1969.
4.	ihl-rat LC50:500 ppm/4H	UCDS** Union Carbide Data Sheet. (Industrial Medicine and Toxicology Dept., Union Carbide Corp., 270 Park Ave., New York, NY 10017) 9/17 ,1969.
5.	skn-rbt LD50:250 mg/kg	UCDS** Union Carbide Data Sheet. (Industrial Medicine and Toxicology Dept., Union Carbide Corp., 270 Park Ave., New York, NY 10017) 9/17 ,1969.

2-Methoxyethyl acrylate Consensus Reports

Glycol ether compounds are on the Community Right-To-Know List. Reported in EPA TSCA Inventory.

2-Methoxyethyl acrylate Safety Profile

Poison by skin contact. Moderately toxic by ingestion and inhalation. Experimental reproductive effects. A skin irritant. Flammable when exposed to heat or flame; can react with oxidizing materials. To fight fire, use foam, CO₂, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes. See also GLYCOL ETHERS.
Safety Information of Methyl cellosolve acrylate (CAS NO.3121-61-7):
Hazard Codes: T
Risk Statements: 20/22-24-41-61-60
20: Harmful by inhalation
22: Harmful if swallowed
24: Toxic in contact with skin
41: Risk of serious damage to eyes
60: May impair fertility
61: May cause harm to the unborn child
Safety Statements: 16-26-36/37/39-45-53
16: Keep away from sources of ignition - No smoking
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36: Wear suitable protective clothing
37: Wear suitable gloves
39: Wear eye/face protection
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)

2-Methoxyethyl acrylate Specification

Methyl cellosolve acrylate ,its CAS NO. is 3121-61-7,the synonyms is 2-Methoxy-ethanoacrylate ; 2-Methoxyethanol,acrylate ; 2-Propenoicacid,2-methoxyethylester ; Glycolmonomethyletheracrylate ; Methylcellosolveacrylate ; Sipomermca ; Acrylic acid 2-methoxyethyl ester ; 2-Methoxyethyl acrylate .

Product Name

2-Methoxyethyl acrylate

Synthetic route

2-Methoxyethyl acrylate Chemical Properties

2-Methoxyethyl acrylate Toxicity Data With Reference

2-Methoxyethyl acrylate Consensus Reports

2-Methoxyethyl acrylate Safety Profile

2-Methoxyethyl acrylate Specification

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