3-(Methylthio)propionaldehyde supplier

Name
3-(Methylthio)propionaldehyde
EINECS 221-882-5
CAS No. 3268-49-3
Article Data50
CAS DataBase
Density 0.984 g/cm³
Solubility It is readily soluble in alcohol solvents such as ethanol, propylene and glycol oil. It is insoluble in water.
Melting Point -68 °C
Formula C₄H₈OS
Boiling Point 168.2 °C at 760 mmHg
Molecular Weight 104.173
Flash Point 61.1 °C
Transport Information UN 2785 6.1/PG 3
Appearance colorless to amber liquid with an extremely foul and persistent odor
Safety 26-36/37/39-45-37/39
Risk Codes 20/22-34-36/37/38-20
Molecular Structure
Hazard Symbols Xn， C
Synonyms Propionaldehyde,3-(methylthio)- (6CI,7CI,8CI);3-(Methylmercapto)propionaldehyde;3-(Methylthio)propanal;3-Methylsulfanylpropionaldehyde;Methional;NSC 15874;b-(Methylmercapto)propionaldehyde;b-(Methylthio)propionaldehyde;b-(Methylthio)propionic aldehyde;3-Methylthio propionaldehyde;
PSA 42.37000
LogP 0.93840

Synthetic route

: 505-10-2
3-(methylthio)-1-propanol

: 3268-49-3
3-(methylsulfenyl)propanal

Conditions

Conditions	Yield
With (NH4)4[CuMo6O18(OH)6]·5H2O; oxygen; sodium sulfite In water; acetonitrile at 60℃; under 760.051 Torr; for 12h;	96%
With 1-methyl-1H-imidazole; [2,2]bipyridinyl; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; tetrakis(acetonitrile)copper(I) trifluoromethanesulfonate In acetonitrile at 20℃; for 24h;	25%
With 5H3N5H(1+)IMo6O24(5-); oxygen; sodium acetate In water; acetonitrile at 70℃; under 760.051 Torr; for 15h; Green chemistry;	97 %Chromat.
With 1-methyl-1H-imidazole; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; C22H16BrCuF2N2O2 In acetonitrile at 20℃; for 24h; Reagent/catalyst;	78 %Chromat.

: 3-methanesulfinyl-propionaldehyde

: 3268-49-3
3-(methylsulfenyl)propanal

Conditions

Conditions	Yield
With N,N,N’,N’-tetrabromobenzene-1,3-disulfonamide; triphenylphosphine In dichloromethane at 20℃; for 0.0166667h;	90%

: 74-93-1
methylthiol

: 598-54-9, 142-71-2, 4180-12-5, 24381-58-6, 66760-61-0, 66760-62-1
copper (I) acetate

: 107-02-8
acrolein

: 3268-49-3
3-(methylsulfenyl)propanal

Conditions

Conditions	Yield
With hydroquinone	88.5%

...Expand

: 87251-88-5
Fructose-methionine Amadori intermediate

A: 64265-26-5
2,4-Dimethyltetrahydrofuran

B: 96-54-8
N-Methylpyrrole

C: 109-08-0
2-Methylpyrazine

D: 1122-62-9
2-acetylpyridine

E: 3268-49-3
3-(methylsulfenyl)propanal

F: 3740-59-8
3,4-dihydro-6-methyl-2H-pyran-2-one

Conditions

Conditions	Yield
at 260℃; for 0.0833333h; Thermal degradation;	A n/a B n/a C n/a D n/a E 70% F n/a

...Expand

: 74-93-1
methylthiol

: 107-02-8
acrolein

: 3268-49-3
3-(methylsulfenyl)propanal

Conditions

Conditions	Yield
at 0℃;	41%
With copper diacetate
With pyridine; copper diacetate

: 54974-63-9
3-(methylthio)propionitrile

: 3268-49-3
3-(methylsulfenyl)propanal

Conditions

Conditions	Yield
With hydrogenchloride; tin(ll) chloride

: 16630-61-8
1,1-diethoxy-3-methylsulfanyl-propane

: 3268-49-3
3-(methylsulfenyl)propanal

Conditions

Conditions	Yield
With hydrogenchloride; water

: 74-93-1
methylthiol

: 121-44-8
triethylamine

: 107-02-8
acrolein

: 3268-49-3
3-(methylsulfenyl)propanal

Conditions

Conditions	Yield
reagiert analog mit Thioessigsaeure;
reagiert analog mit Thioessigsaeure;

...Expand

: 74-93-1
methylthiol

: 124-41-4
sodium methylate

: 107-02-8
acrolein

: 71-43-2
benzene

: 3268-49-3
3-(methylsulfenyl)propanal

...Expand

: 2373-51-5
chloro-methylsulfanyl-methane

: 75-01-4
chloroethylene

: 3268-49-3
3-(methylsulfenyl)propanal

Conditions

Conditions	Yield
With sulfuric acid

: 485-47-2
indan-1,2,3-trione hydrate

: 59-51-8
DL-methionine

NaCl: NaCl

aqueous KH2PO4: aqueous KH2PO4

: 3268-49-3
3-(methylsulfenyl)propanal

Conditions

Conditions	Yield
(+-)-2-amino-4-methylsulfanyl-butyric acid;

...Expand

: 74-93-1
methylthiol

: 74-85-1
ethene

carbon monoxide: carbon monoxide

A: 624-89-5
Ethyl methyl sulfide

B: 3268-49-3
3-(methylsulfenyl)propanal

Conditions

Conditions	Yield
With di-tert-butyl peroxide at 130℃; under 2206520 Torr;
With di-tert-butyl peroxide at 130℃; under 2206520 Torr;

...Expand

: 74-93-1
methylthiol

: 74-85-1
ethene

: 110-05-4
di-tert-butyl peroxide

carbon monoxide: carbon monoxide

A: 624-89-5
Ethyl methyl sulfide

B: 3268-49-3
3-(methylsulfenyl)propanal

Conditions

Conditions	Yield
at 130℃; under 2206520 Torr;

...Expand

: 59-51-8
DL-methionine

: 3268-49-3
3-(methylsulfenyl)propanal

Conditions

Conditions	Yield
With perchloric acid; cerium(IV) ammonium sulphate; sulfuric acid at 31℃; for 1h; Kinetics; Further Variations:; Temperatures; pH-values;

: 863608-03-1
acetic acid 1-(4,5-dimethoxy-2-nitrobenzyloxy)-3-methylsulfanylpropyl ester

: 3268-49-3
3-(methylsulfenyl)propanal

Conditions

Conditions	Yield
In [D3]acetonitrile for 4h; Irradiation;

: 583-92-6
4-methylthio-2-oxobutanoic acid

: 3268-49-3
3-(methylsulfenyl)propanal

Conditions

Conditions	Yield
With 1,4-dihydronicotinamide adenine dinucleotide; horse liver alcohol dehydrogenase In phosphate buffer at 30℃; pH=6.0; Enzyme kinetics;

: 74-93-1
methylthiol

: 107-02-8
acrolein

A: 3-hydroxy-2-methylthiomethyl-4-pentenal

B: 3268-49-3
3-(methylsulfenyl)propanal

C: 59902-01-1
5-methylsulfanyl-2-methylsulfanylmethyl-pent-2-enal

Conditions

Conditions	Yield
With pyridine; acetic acid at 70℃; for 0.75 - 0.833333h;	A 0.23 - 0.73 %Chromat. B 87.79 - 89.26 %Chromat. C 0.06 - 0.12 %Chromat.

...Expand

: 81382-04-9
1,1,3-tris-methylsulfanyl-propane

: 107-02-8
acrolein

: 3268-49-3
3-(methylsulfenyl)propanal

Conditions

Conditions	Yield
dimethylaminomethylpolystyrene at 0℃; for 2h;

: 74-93-1
methylthiol

: 56-81-5
glycerol

: 3268-49-3
3-(methylsulfenyl)propanal

Conditions

Conditions	Yield
zeolith HZSM-5 (Modul 28, H0 <-8.2) In methanol at 300℃; under 45754.6 Torr; for 1h; Product distribution / selectivity;
zeolith ammonium β CP 814E (H0 <-3.0) In methanol at 100 - 300℃; under 2250.23 - 30003 Torr; for 4.5h; Product distribution / selectivity;

: 59-51-8
DL-methionine

A: 1927-25-9
DL-Homoserine

B: 3268-49-3
3-(methylsulfenyl)propanal

C: 3226-65-1
methionine S-oxide

Conditions

Conditions	Yield
With water; oxygen pH=7; Mechanism; Quantum yield; γ-irradiation;
With water; oxygen; dinitrogen monoxide pH=7; Mechanism; Quantum yield; γ-irradiation;

...Expand

: 59-51-8
DL-methionine

A: 4104-45-4
3-methylthio-1-propanamine

B: 3268-49-3
3-(methylsulfenyl)propanal

C: 3226-65-1
methionine S-oxide

D: 2835-81-6
2-aminobutanoic acid

Conditions

Conditions	Yield
With water; dinitrogen monoxide Mechanism; Quantum yield; γ-irradiation;

...Expand

: 63-68-3
L-methionine

: 3268-49-3
3-(methylsulfenyl)propanal

Conditions

Conditions	Yield
With potassium permanganate; sodium perchlorate; sodium hydroxide In water at 35℃; Kinetics; Concentration; Reagent/catalyst; Temperature;

: 74-93-1
methylthiol

: 107-02-8
acrolein

A: 3268-49-3
3-(methylsulfenyl)propanal

B: 3-(methylthio)propanal hydrate

Conditions

Conditions	Yield
In aq. phosphate buffer; water-d2 for 0.333333h; pH=7;

...Expand

: 3268-49-3
3-(methylsulfenyl)propanal

: 505-10-2
3-(methylthio)-1-propanol

Conditions

Conditions	Yield
With hydrogen; phosphotungstic acid 44-hydrate; [Fe(C5H4P(i-Pr)2)2Rh(C8H12)]BF4 In water; isopropyl alcohol at 20℃; under 5171.62 Torr; for 16h;	100%
With sodium tetrahydroborate at 0 - 20℃;	99%

: 3268-49-3
3-(methylsulfenyl)propanal

: 3-methanesulfinyl-propionaldehyde

Conditions

Conditions	Yield
With Mn(III) Schiff-base; dihydrogen peroxide In water; acetic acid at 20℃; for 0.116667h;	100%
With C44H55ClMnN4O2(2+)*2I(1-); dihydrogen peroxide In water at 20℃; for 0.416667h; chemoselective reaction;	100%
With dihydrogen peroxide; Amberlyst 15 In methanol at 20℃; for 0.1h;	98%

: 3268-49-3
3-(methylsulfenyl)propanal

: 7633-32-1
tert-butyl glyoxylate

: 768-03-6
Phenyl vinyl ketone

: tert-butyl 3-methyl-2-(3-methylsulfanylpropionyloxy)-4-oxo-4-phenylbutanoate

Conditions

Conditions	Yield
[Rh(bis(diphenylphosphanyl)ethane)]ClO4 In 1,2-dichloro-ethane at 70℃; for 16h;	99%
With (bicyclo[2.2.1]hepta-2,5-diene)(1,2-bis(diphenylphosphanyl)ethane)rhodium(I) perchlorate; hydrogen In 1,2-dichloro-ethane at 70℃; for 18h; Inert atmosphere; optical yield given as %de;	83%

...Expand

: 74-90-8
hydrogen cyanide

: 3268-49-3
3-(methylsulfenyl)propanal

: 17773-41-0
2-hydroxy-4-(methylthio)butyronitrile

Conditions

Conditions	Yield
With ammonia In water at 35 - 40℃; Temperature; Large scale;	98.8%
With ammonia at 55℃; Reagent/catalyst; Inert atmosphere;	96.1%
With potassium cyanide

: 3268-49-3
3-(methylsulfenyl)propanal

: 693-02-7
hex-1-yne

: (E)-1-methylsulfanyl-non-4-en-3-one

Conditions

Conditions	Yield
[Rh(bis(diphenylphosphanyl)ethane)]ClO4 In acetone at 55℃; for 1h;	98%
With bis(norbornadiene)rhodium(l)tetrafluoroborate; 1,2-bis-(diphenylphosphino)ethane In 1,2-propylene cyclic carbonate at 70℃; for 1h; Inert atmosphere;	91%

: 3268-49-3
3-(methylsulfenyl)propanal

: hydrocyanic acid

: 17773-41-0
2-hydroxy-4-(methylthio)butyronitrile

Conditions

Conditions	Yield
With pyridine at 45℃;	98%

: 3268-49-3
3-(methylsulfenyl)propanal

: 32644-22-7, 70000-51-0, 62014-64-6, 2327-98-2
1-methyl-3-phenylallene

: 1173936-70-3
(E)-4-methyl-1-(methylthio)-6-phenylhex-5-en-3-one

Conditions

Conditions	Yield
With [Rh(dppe)]ClO4 In acetone at 55℃; Inert atmosphere; regioselective reaction;	97%

: 3268-49-3
3-(methylsulfenyl)propanal

: 17773-41-0
2-hydroxy-4-(methylthio)butyronitrile

Conditions

Conditions	Yield
With sodium hydroxide; hydrogen isocyanide; sulfuric acid In methanol	96.1%
With hydrogen cyanide; dimethylaminomethylpolystyrene at 35 - 40℃; for 0.5h;

: 3268-49-3
3-(methylsulfenyl)propanal

: 1606-47-9
isopropyl vinyl ketone

: 7633-32-1
tert-butyl glyoxylate

: 1097736-14-5
tert-butyl 3,5-dimethyl-2-(3-(methylthio)propanoyloxy)-4-oxohexanoate

Conditions

Conditions	Yield
With (bicyclo[2.2.1]hepta-2,5-diene)(1,2-bis(diphenylphosphanyl)ethane)rhodium(I) perchlorate; hydrogen In 1,2-dichloro-ethane at 70℃; for 18h; Inert atmosphere; optical yield given as %de;	96%

...Expand

: 3268-49-3
3-(methylsulfenyl)propanal

: 74268-51-2
ethyl 2,3-pentadienecarboxylate

: 1173936-79-2
ethyl (E)-4-methyl-7-(methylthio)-5-oxohept-3-enoate

Conditions

Conditions	Yield
With [Rh(dppe)]ClO4 In acetone at 55℃; Inert atmosphere; regioselective reaction;	96%

: 5390-04-5
pent-1-yn-5-ol

: 3268-49-3
3-(methylsulfenyl)propanal

: (E)-8-hydroxy-1-methylsulfanyl-oct-4-en-3-one

Conditions

Conditions	Yield
[Rh(bis(diphenylphosphanyl)ethane)]ClO4 In acetone at 55℃; for 1h;	95%

: tetraethylammonium petntacarbonylcyanotungstate

: 3268-49-3
3-(methylsulfenyl)propanal

: 119072-55-8, 7188-38-7
tert-butylisonitrile

: 142-04-1
aniline hydrochloride

: pentacarbonyltungsten(Δ4-(CNHC(HN(t-Bu))C(CH2CH2SMe)N(Ph)))

Conditions

Conditions	Yield
In methanol to a stirred soln. of Cr-compd. the aldehyde is added via syringe followed by isocyanide at ice-bath temp., to this soln. a soln. of amine hydrochloride is added (Ar); mixt. is allowed to warm to room temp. overnight, silica gel is added and mixt. is evapd., ppt. is chromd. (silica gel; n-pentane/diethyl ether), recrystd. from CH2Cl2/pentane, elem. anal.;	95%

...Expand

: 3268-49-3
3-(methylsulfenyl)propanal

: C12H10N2O2

: methyl (1-((methylthio)methyl)-3H-benzo[e]indol-3-yl)carbamate

Conditions

Conditions	Yield
With pyrrolidine; acetic acid In dichloromethane at 20℃; for 24h;	95%
With pyrrolidine; acetic acid In dichloromethane at 20℃; for 48h;	95%

: 1629-58-9
4-penten-3-one

: 3268-49-3
3-(methylsulfenyl)propanal

: 7633-32-1
tert-butyl glyoxylate

: 1097736-12-3
tert-butyl 3-methyl-2-(3-(methylthio)propanoyloxy)-4-oxohexanoate

Conditions

Conditions	Yield
With (bicyclo[2.2.1]hepta-2,5-diene)(1,2-bis(diphenylphosphanyl)ethane)rhodium(I) perchlorate; hydrogen In 1,2-dichloro-ethane at 70℃; for 18h; Inert atmosphere; optical yield given as %de;	94%

...Expand

: 62992-46-5
1-(tetrahydropyranyloxy)-4-pentyn

: 3268-49-3
3-(methylsulfenyl)propanal

: (E)-1-methylsulfanyl-8-(tetrahydro-pyran-2-yloxy)-oct-4-en-3-one

Conditions

Conditions	Yield
[Rh(bis(diphenylphosphanyl)ethane)]ClO4 In acetone at 55℃; for 1h;	93%

: 3268-49-3
3-(methylsulfenyl)propanal

: 4301-14-8
acetylenemagnesium bromide

: 1227268-10-1
5-(methylsulfanyl)pent-1-yn-3-ol

Conditions

Conditions	Yield
In tetrahydrofuran at 0 - 20℃; for 2h;	93%
Stage #1: 3-(methylsulfenyl)propanal; acetylenemagnesium bromide In tetrahydrofuran at 0℃; Inert atmosphere; Stage #2: With water; ammonium chloride In tetrahydrofuran

: 60-35-5
acetamide

: 3268-49-3
3-(methylsulfenyl)propanal

: 201230-82-2
carbon monoxide

A: 1115-47-5
N-acetyl-DL-methionine

B: 24949-35-7
1,3-bis(methylthio)propane

Conditions

Conditions	Yield
With hydrogen; dicobalt octacarbonyl In acetic acid butyl ester at 70℃; under 97509.8 Torr; for 8h; Product distribution / selectivity;	A 92.2% B 5%
With hydrogen; dicobalt octacarbonyl In acetic acid butyl ester at 70℃; under 97509.8 Torr; for 8h; Product distribution / selectivity;	A 92.2% B n/a

...Expand

: 111-66-0
oct-1-ene

: 3268-49-3
3-(methylsulfenyl)propanal

: 1-(methylsulfanyl)undecan-3-one

Conditions

Conditions	Yield
With C21H44N2P2Rh*C32H12BF24 In acetone at 55℃; for 3h; Inert atmosphere;	92%
With silver perchlorate; chloro(1,5-cyclooctadiene)rhodium(I) dimer In acetone at 55℃; for 24h;	70%
With chloro(1,5-cyclooctadiene)rhodium(I) dimer; silver perchlorate; bis[2-(diphenylphosphino)phenyl] ether In acetone at 55℃; for 24h; Inert atmosphere;	67%

: 3268-49-3
3-(methylsulfenyl)propanal

: 7633-32-1
tert-butyl glyoxylate

: 73291-51-7
(E)-1-phenylpenta-1,4-dien-3-one

: 1097736-16-7
(E)-tert-butyl 3-methyl-2-(3-(methylthio)propanoyloxy)-4-oxo-6-phenylhex-5-enoate

Conditions

Conditions	Yield
With (bicyclo[2.2.1]hepta-2,5-diene)(1,2-bis(diphenylphosphanyl)ethane)rhodium(I) perchlorate; hydrogen In 1,2-dichloro-ethane at 70℃; for 18h; Inert atmosphere; optical yield given as %de;	92%

...Expand

: 3268-49-3
3-(methylsulfenyl)propanal

: 7633-32-1
tert-butyl glyoxylate

: 78-94-4
methyl vinyl ketone

: 1097736-11-2
tert-butyl 3-methyl-2-(3-(methylthio)propanoyloxy)-4-oxopentanoate

Conditions

Conditions	Yield
With (bicyclo[2.2.1]hepta-2,5-diene)(1,2-bis(diphenylphosphanyl)ethane)rhodium(I) perchlorate; hydrogen In 1,2-dichloro-ethane at 70℃; for 18h; Inert atmosphere; optical yield given as %de;	92%

...Expand

: 3268-49-3
3-(methylsulfenyl)propanal

: 1173936-60-1
C11H20

: 1173936-68-9
(E)-4-((3-methylbut-1-enyl)-1-methylthio)nonan-3-one

Conditions

Conditions	Yield
With [Rh(dppe)]ClO4 In acetone at 55℃; Inert atmosphere; regioselective reaction;	92%

: 3268-49-3
3-(methylsulfenyl)propanal

: 530-47-2
N,N-diphenylhydrazine hydrochloride

: (E)-2-(3-(methylthio)propylidene)-1,1-diphenylhydrazine

Conditions

Conditions	Yield
With sodium acetate; magnesium sulfate In dichloromethane at 20℃; Inert atmosphere;	92%

: 3268-49-3
3-(methylsulfenyl)propanal

: 13191-29-2
thienyl vinyl ketone

: 7633-32-1
tert-butyl glyoxylate

: 1097736-17-8
tert-butyl-3-methyl-2-(3-(methylthio)propanoyloxy)-4-oxo-4-(thiophen-2-yl)butanoate

Conditions

Conditions	Yield
With (bicyclo[2.2.1]hepta-2,5-diene)(1,2-bis(diphenylphosphanyl)ethane)rhodium(I) perchlorate; hydrogen In 1,2-dichloro-ethane at 70℃; for 18h; Inert atmosphere; optical yield given as %de;	91%

...Expand

: 629-05-0
n-octyne

: 3268-49-3
3-(methylsulfenyl)propanal

: 1321899-91-5
(E)-1-(methylthio)undec-4-en-3-one

Conditions

Conditions	Yield
With bis(norbornadiene)rhodium(l)tetrafluoroborate; 1,2-bis-(diphenylphosphino)ethane In 1,2-propylene cyclic carbonate at 70℃; for 1h; Inert atmosphere;	91%

: 109-80-8
1.3-propanedithiol

: 3268-49-3
3-(methylsulfenyl)propanal

: 73401-96-4
2-(2-(methylthio)ethyl)-1,3-dithiane

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate In dichloromethane at 0 - 20℃;	91%

: 60-35-5
acetamide

: 3268-49-3
3-(methylsulfenyl)propanal

: 201230-82-2
carbon monoxide

A: cobalt acetylmethionate

B: 1115-47-5
N-acetyl-DL-methionine

Conditions

Conditions	Yield
Stage #1: acetamide; 3-(methylsulfenyl)propanal; carbon monoxide With hydrogen; dicobalt octacarbonyl In ethyl acetate at 80℃; under 97509.8 Torr; for 5h; Stage #2: With oxygen at 20 - 80℃; under 7500.75 Torr;	A 90% B 80.7%

...Expand

: 3268-49-3
3-(methylsulfenyl)propanal

: 536-74-3
phenylacetylene

: 84175-29-1
(E)-5-(methylthio)-1-phenylpent-1-en-3-one

Conditions

Conditions	Yield
With bis(norbornadiene)rhodium(l)tetrafluoroborate; 1,2-bis-(diphenylphosphino)ethane In 1,2-propylene cyclic carbonate at 70℃; for 1h; Inert atmosphere;	90%

: 931-53-3
Cyclohexyl isocyanide

: 3268-49-3
3-(methylsulfenyl)propanal

: 95-54-5
1,2-diamino-benzene

: 1523157-59-6
N-cyclohexyl-3-(2-(methylthio)ethyl)quinoxaline-2-amine

Conditions

Conditions	Yield
With N,N,N’,N’-tetrabromobenzene-1,3-disulfonamide In ethanol at 20℃; for 1.3h; Ugi Condensation;	90%

...Expand

3-(Methylthio)propionaldehyde Chemical Properties

Molecular Structure of Methional (CAS NO.3268-49-3):

IUPAC Name: 3-Methylsulfanylpropanal
Canonical SMILES: CSCCC=O
InChI: InChI=1S/C4H8OS/c1-6-4-2-3-5/h3H,2,4H2,1H3
InChIKey: CLUWOWRTHNNBBU-UHFFFAOYSA-N
Molecular Weight: 104.17072 [g/mol]
Molecular Formula: C₄H₈OS
XLogP3-AA: 0.3
H-Bond Donor: 0
H-Bond Acceptor: 1
EINECS: 221-882-5
Product Categories: sulfide Flavor; Sulfides flavors
storage temp.: 2-8 °C
Melting Point: -68 °C
Index of Refraction: 1.455
Molar Refractivity: 28.76 cm³
Molar Volume: 105.8 cm³
Surface Tension: 31.5 dyne/cm
Density: 0.984 g/cm³
Flash Point: 61.1 °C
Enthalpy of Vaporization: 40.46 kJ/mol
Boiling Point: 168.2 °C at 760 mmHg
Vapour Pressure: 1.64 mmHg at 25 °C
Sensitive Air Sensitive
Appearance: colorless to amber liquid with an extremely foul and persistent odor
Classification Code: Hormone Antagonists; Hormones, Hormone Substitutes, and Hormone Antagonists; Prostaglandin antagonists; Skin / Eye Irritant

3-(Methylthio)propionaldehyde Uses

Methional (CAS NO.3268-49-3) is used as a food additive.

3-(Methylthio)propionaldehyde Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LC50	inhalation	5400mg/m3/2H (5400mg/m3)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 49(1), Pg. 85, 1984.
mouse	LD50	oral	1620mg/kg (1620mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 49(1), Pg. 85, 1984.
rabbit	LDLo	skin	2500mg/kg (2500mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: EXCITEMENT	National Technical Information Service. Vol. OTS0534366,
rat	LC50	inhalation	5820mg/m3/4H (5820mg/m3)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 49(1), Pg. 85, 1984.
rat	LD50	oral	700mg/kg (700mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS GASTROINTESTINAL: ALTERATION IN GASTRIC SECRETION	National Technical Information Service. Vol. OTS0546239,

3-(Methylthio)propionaldehyde Consensus Reports

Reported in EPA TSCA Inventory.

3-(Methylthio)propionaldehyde Safety Profile

Safety Information of Methional (CAS NO.3268-49-3):
Hazard Codes: Corrosive C, Harmful Xn
Risk Statements: 20/22-34-36/37/38-20
R20/22:Harmful by inhalation and if swallowed.
R34:Causes burns.
R36/37/38:Irritating to eyes, respiratory system and skin.
R20:Harmful by inhalation.
Safety Statements: 26-36/37/39-45-37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S37/39:Wear suitable gloves and eye/face protection.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 2785 6.1/PG 3
WGK Germany: 1
RTECS: UE2285000
F: 10-13-23
HazardClass: 6.1(b)
PackingGroup: III
Moderately toxic by ingestion. When heated to decomposition it emits toxic vapors of SO_x.

3-(Methylthio)propionaldehyde Standards and Recommendations

DOT Classification: 6.1; Label: KEEP AWAY FROM FOOD

3-(Methylthio)propionaldehyde Specification

Methional (CAS NO.3268-49-3), its Synonyms are 3-(Methylmercapto)propionaldehyde ; 3-(Methylthio)propanal ; 3-(Methylthio)propionaldehyde ; 3-Methylmercaptopropyl aldehyde ; Methylmercaptopropionic aldehyde ; beta-(Methylmercapto)propionaldehyde ; beta-(Methylthio)propionaldehyde ; Propanal, 3-(methylthio)- ; Propionaldehyde, 3-(methylthio)- . It is slightly soluble in water and denser than water and if contact it may slightly irritate skin, eyes and mucous membranes.

Product Name

3-(Methylthio)propionaldehyde

Synthetic route

3-(Methylthio)propionaldehyde Chemical Properties

3-(Methylthio)propionaldehyde Uses

3-(Methylthio)propionaldehyde Toxicity Data With Reference

3-(Methylthio)propionaldehyde Consensus Reports

3-(Methylthio)propionaldehyde Safety Profile

3-(Methylthio)propionaldehyde Standards and Recommendations

3-(Methylthio)propionaldehyde Specification

Related Products

Hot Products