3-Bromo-3,3-difluoropropene supplier

Name
3-Bromo-3,3-difluoropropene
EINECS 810-594-0
CAS No. 420-90-6
Article Data8
CAS DataBase
Density 1.614 g/cm³
Solubility
Melting Point 53-54 °C
Formula C₃H₃BrF₂
Boiling Point 41.999 °C at 760 mmHg
Molecular Weight 156.958
Flash Point -4.642 °C
Transport Information
Appearance
Safety 26-36/37/39
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms Propene,3-bromo-3,3-difluoro- (6CI,7CI,8CI);1,1-Difluoroallyl bromide;3-Bromo-3,3-difluoro-1-propene;
PSA 0.00000
LogP 2.16010

Synthetic route

: 460-25-3
1,1-difluoro-1,3-dibromopropane

: 420-90-6
3-bromo-3,3-difluropropene

Conditions

Conditions	Yield
With potassium hydroxide

: 460-25-3
1,1-difluoro-1,3-dibromopropane

A: 420-90-6
3-bromo-3,3-difluropropene

B: 60917-29-5
1,1-difluoro-3-bromo-1-propene

Conditions

Conditions	Yield
With potassium hydroxide at 115 - 130℃; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
With potassium hydroxide In water at 120 - 160℃; Yield given. Yields of byproduct given;
With potassium hydroxide In water at 90 - 110℃; for 3h;

: 460-25-3
1,1-difluoro-1,3-dibromopropane

aqueous KOH-solution: aqueous KOH-solution

: 420-90-6
3-bromo-3,3-difluropropene

Conditions

Conditions	Yield
at 80℃;

: 74-85-1
ethene

: 75-61-6
dibromodifluoromethane

: 420-90-6
3-bromo-3,3-difluropropene

: 420-90-6
3-bromo-3,3-difluropropene

: 100-52-7
benzaldehyde

: 85864-61-5
2,2-difluoro-1-phenyl-3-buten-1-ol

Conditions

Conditions	Yield
With indium In water at 20℃; for 3h; Addition;	100%
With indium In N,N-dimethyl-formamide for 3h; Ambient temperature;	99%
With ammonium chloride; zinc In tetrahydrofuran allylation;	84%

: 420-90-6
3-bromo-3,3-difluropropene

: 66-25-1
hexanal

: 131437-07-5
3,3-difluoro-1-nonen-4-ol

Conditions

Conditions	Yield
With indium In water for 3h;	100%
With zinc In tetrahydrofuran	47%
With indium In N,N-dimethyl-formamide

: 420-90-6
3-bromo-3,3-difluropropene

: 104-55-2
3-phenyl-propenal

: 88257-89-0
4,4-difluoro-1-phenylhexa-1,5-dien-3-ol

Conditions

Conditions	Yield
With indium In water at 20℃; for 3h; Addition;	100%
With zinc In tetrahydrofuran 1.) 0 deg C to RT, 4.5 h; 2.) RT, overnight;	74%

: 124-19-6
nonan-1-al

: 420-90-6
3-bromo-3,3-difluropropene

: 3,3-difluorododec-1-en-4-ol

Conditions

Conditions	Yield
With indium In water at 20℃; for 3h; Addition;	100%
With indium In N,N-dimethyl-formamide for 3h; Ambient temperature;	93%

: 420-90-6
3-bromo-3,3-difluropropene

: 105-07-7
4-cyanobenzaldehyde

: 4-(2,2-difluoro-1-hydroxybut-3-en-1-yl)benzonitrile

Conditions

Conditions	Yield
With indium In N,N-dimethyl-formamide at 20℃;	100%

: 50-00-0
formaldehyd

: 420-90-6
3-bromo-3,3-difluropropene

: 2,2-difluoro-3-butene-1-ol

Conditions

Conditions	Yield
With indium; lithium iodide In N,N-dimethyl-formamide	100%
With lithium iodide In N,N-dimethyl-formamide at 22℃; for 12h;

: 18829-55-5
(E)-2-Heptenal

: 420-90-6
3-bromo-3,3-difluropropene

: (E)-3,3-Difluoro-deca-1,5-dien-4-ol

Conditions

Conditions	Yield
With indium In N,N-dimethyl-formamide for 3h; Ambient temperature;	99%

: 420-90-6
3-bromo-3,3-difluropropene

: 2463-63-0
3-Butyl-acrolein

: 3,3-difluorodeca-1,5-dien-4-ol

Conditions

Conditions	Yield
With indium In N,N-dimethyl-formamide at 20℃; for 3h; Addition;	99%

: 420-90-6
3-bromo-3,3-difluropropene

: 155396-71-7
tert-butyl N-(phenyl(phenylsulfonyl)methyl)carbamate

: 1095387-06-6
C15H19F2NO2

Conditions

Conditions	Yield
Stage #1: 3-bromo-3,3-difluropropene With zinc(II) chloride In N,N-dimethyl-formamide at 20℃; for 1h; Stage #2: tert-butyl N-(phenyl(phenylsulfonyl)methyl)carbamate In N,N-dimethyl-formamide at 20℃; for 1h;	99%

: 420-90-6
3-bromo-3,3-difluropropene

: 108-98-5
thiophenol

: (3,3-difluoro-2-propen-1-yl)phenyl sulfide

Conditions

Conditions	Yield
Stage #1: thiophenol With sodium hydride In 1,4-dioxane at 0℃; for 0.25h; Inert atmosphere; Sonication; Stage #2: 3-bromo-3,3-difluropropene In 1,4-dioxane at 0 - 20℃; for 1h; Inert atmosphere;	99%
Stage #1: thiophenol With sodium hydride for 0.0833333h; Inert atmosphere; Stage #2: 3-bromo-3,3-difluropropene at 20℃; for 1h; Inert atmosphere;	99%

: 420-90-6
3-bromo-3,3-difluropropene

: C10H17O4(1-)*Na(1+)

: tert-butyl ethyl 2-(3,3-difluoroprop-2-enyl)isobutan-1,3-dioate

Conditions

Conditions	Yield
With palladium diacetate; triphenylphosphine In tetrahydrofuran at 40℃; for 2h; Alkylation;	98%

: 420-90-6
3-bromo-3,3-difluropropene

: 95715-87-0
(R)-3-tert-butoxycarbonyl-4-formyl-2,2-dimethyloxazolidine

: 1056467-63-0
C14H23F2NO4

Conditions

Conditions	Yield
With indium; lithium iodide In N,N-dimethyl-formamide	98%

: 420-90-6
3-bromo-3,3-difluropropene

: 123-08-0
4-hydroxy-benzaldehyde

: 2,2-difluoro-1-(p-hydroxyphenyl)but-3-en-1-ol

Conditions

Conditions	Yield
With indium In N,N-dimethyl-formamide for 3h; Ambient temperature;	97%
With indium In N,N-dimethyl-formamide at 20℃; for 3h; Addition;	97%

: 420-90-6
3-bromo-3,3-difluropropene

: 18424-77-6
sodium diethyl methylmalonate

: 288302-72-7
diethyl 2-(3,3-difluoroprop-2-enyl)isobutan-1,3-dioate

Conditions

Conditions	Yield
With palladium diacetate; triphenylphosphine In tetrahydrofuran at 40℃; for 2h; Alkylation;	97%

: 420-90-6
3-bromo-3,3-difluropropene

: 112897-03-7
3-(tert-butyldiphenylsilyloxy)-1-propanal

: 1310565-93-5
1-(tert-butyldiphenylsilyloxy)-4,4-difluoro-5-hexen-3-ol

Conditions

Conditions	Yield
Stage #1: 3-bromo-3,3-difluropropene With indium In water at 20℃; for 0.166667h; Stage #2: 3-(tert-butyldiphenylsilyloxy)-1-propanal In tetrahydrofuran; water for 5h;	97%
Stage #1: 3-bromo-3,3-difluropropene With indium; lithium iodide In water at 20℃; for 0.166667h; Stage #2: 3-(tert-butyldiphenylsilyloxy)-1-propanal In tetrahydrofuran; water at 20℃; for 5h;	97%
With indium In tetrahydrofuran; water at 20℃; for 2h;	93%
With indium In tetrahydrofuran; water at 20 - 60℃; Inert atmosphere;	90%
With indium	90%

: 420-90-6
3-bromo-3,3-difluropropene

: 95-56-7
2-hydroxybromobenzene

: 1565823-27-9
1-bromo-2-((1’,1’-difluoroallyl)oxy)benzene

Conditions

Conditions	Yield
With palladium diacetate; sodium hydride; triphenylphosphine In tetrahydrofuran at 0 - 40℃; for 0.5h; Catalytic behavior; Reagent/catalyst; Tsuji-Trost Allylation; Inert atmosphere; regioselective reaction;	97%
With palladium diacetate; sodium hydride; triphenylphosphine In tetrahydrofuran at 0 - 40℃; Tsuji-Trost Allylation; Inert atmosphere;	83%

: 420-90-6
3-bromo-3,3-difluropropene

: 7-bromo-2-(pyridin-2-yl)isoquinolin-1(2H)-one

: 7-bromo-3-(3,3-difluoroallyl)-2-(pyridin-2-yl)isoquinolin-1(2H)-one

Conditions

Conditions	Yield
With bromopentacarbonylmanganese(I); N-cyclohexyl-cyclohexanamine In 1,4-dioxane at 90℃; for 22h;	97%

: 420-90-6
3-bromo-3,3-difluropropene

: 4-methoxy-1-(pyridin-2-yl)-1H-indole

: 2-(3,3-difluoroallyl)-4-methoxy-1-(pyridin-2-yl)-1H-indole

Conditions

Conditions	Yield
With bromopentacarbonylmanganese(I); sodium acetate In 1,4-dioxane at 90℃; for 22h;	97%

: 420-90-6
3-bromo-3,3-difluropropene

: 116359-75-2
3-methyl-1-(pyridine-2-yl)-1H-indole

: 2-(3,3-difluoroallyl)-3-methyl-1-(pyridin-2-yl)-1H-indole

Conditions

Conditions	Yield
With bromopentacarbonylmanganese(I); sodium acetate In 1,4-dioxane at 90℃; for 22h;	97%

: 420-90-6
3-bromo-3,3-difluropropene

: 60656-87-3
benzyloxyacetoaldehyde

: 275377-30-5
1-(benzyloxy)-3,3-difluoropent-4-en-2-ol

Conditions

Conditions	Yield
With indium In N,N-dimethyl-formamide at 20℃; for 6h; sonification;	96%
With indium In N,N-dimethyl-formamide at 20℃; for 5h; allylation; Sonication;	80%

: 420-90-6
3-bromo-3,3-difluropropene

: 695-96-5
2-bromo-4-chlorophenol

: 1565823-30-4
2-bromo-4-chloro-1-(1,1-difluoroallyloxy)benzene

Conditions

Conditions	Yield
With palladium diacetate; sodium hydride; triphenylphosphine In tetrahydrofuran at 0 - 40℃; for 1h; Tsuji-Trost Allylation; Inert atmosphere; regioselective reaction;	96%

: 420-90-6
3-bromo-3,3-difluropropene

: 630-19-3
pivalaldehyde

: 73557-51-4
4,4-Difluoro-2,2-dimethyl-hex-5-en-3-ol

Conditions

Conditions	Yield
With n-butyllithium In tetrahydrofuran; diethyl ether; hexane; pentane at -95℃;	95%

: 420-90-6
3-bromo-3,3-difluropropene

: 96-34-4
methyl chloroacetate

: 85882-51-5
1-Chloro-3,3-difluoro-pent-4-en-2-one

Conditions

Conditions	Yield
With n-butyllithium In tetrahydrofuran; diethyl ether; hexane; pentane at -95℃;	95%

: 420-90-6
3-bromo-3,3-difluropropene

: 1122-91-4
4-bromo-benzaldehyde

: 189949-30-2
1-(p-bromophenyl)-2,2-difluorobut-3-en-1-ol

Conditions

Conditions	Yield
With indium In N,N-dimethyl-formamide for 3h; Ambient temperature;	95%
With indium In N,N-dimethyl-formamide at 20℃; for 3h; Addition;	95%

: 98-01-1
furfural

: 420-90-6
3-bromo-3,3-difluropropene

: 275377-29-2
2,2-difluoro-1-(furan-2-yl)but-3-en-1-ol

Conditions

Conditions	Yield
With indium In N,N-dimethyl-formamide at 20℃; for 4h; sonification;	95%
With indium In N,N-dimethyl-formamide at 20℃; allylation; Sonication;	77%

: 420-90-6
3-bromo-3,3-difluropropene

: 2315-86-8
3-bromo-4-hydroxybenzonitrile

: 3-bromo-4-(1,1-difluoroallyloxy)benzonitrile

Conditions

Conditions	Yield
With palladium diacetate; sodium hydride; triphenylphosphine In tetrahydrofuran at 0 - 40℃; for 0.5h; Tsuji-Trost Allylation; Inert atmosphere; regioselective reaction;	95%

: 109822-12-0
5-chloro-2H-[1,2'-bipyridin]-2-one

: 420-90-6
3-bromo-3,3-difluropropene

: 5-chloro-6-(3,3-difluoroallyl)-2H-[1,2'-bipyridin]-2-one

Conditions

Conditions	Yield
With bromopentacarbonylmanganese(I); N-cyclohexyl-cyclohexanamine In 1,4-dioxane at 90℃; for 22h;	95%

: 420-90-6
3-bromo-3,3-difluropropene

: 5-methoxy-1-(pyridine-2-yl)-1H-indole

: 2-(3,3-difluoroallyl)-5-methoxy-1-(pyridin-2-yl)-1H-indole

Conditions

Conditions	Yield
With bromopentacarbonylmanganese(I); sodium acetate In 1,4-dioxane at 90℃; for 22h;	95%

: 420-90-6
3-bromo-3,3-difluropropene

: 119-36-8
methyl salicylate

: methyl 2-((1’,1’-difluoroallyl)oxy)benzoate

Conditions

Conditions	Yield
With palladium diacetate; sodium hydride; triphenylphosphine In tetrahydrofuran at 0 - 40℃; Tsuji-Trost Allylation; Inert atmosphere;	95%

: 420-90-6
3-bromo-3,3-difluropropene

: 19438-10-9
methyl 3-hydroxybenzoate

: methyl-3-((1’,1’-difluoroallyl)oxy)benzoate

Conditions

Conditions	Yield
With palladium diacetate; sodium hydride; triphenylphosphine In tetrahydrofuran at 0 - 40℃; Tsuji-Trost Allylation; Inert atmosphere;	95%

3-Bromo-3,3-difluoropropene Chemical Properties

Molecular structure of 3-Bromo-3,3-difluoropropene (CAS NO.420-90-6) is:

Product Name: 3-Bromo-3,3-difluoropropene
CAS Registry Number: 420-90-6
Empirical Formula: C₃H₃BrF₂
Molecular Weight: 156.9567
Melting Point: 53-54 °C
Storage temp.: Keep Cold
Surface Tension: 20.4 dyne/cm
Density: 1.613 g/cm³
Enthalpy of Vaporization: 27.44 kJ/mol
Boiling Point: 42 °C at 760 mmHg
Vapour Pressure: 411 mmHg at 25°C

3-Bromo-3,3-difluoropropene Safety Profile

Safty information about 3-Bromo-3,3-difluoropropene (CAS NO.420-90-6) is:
Hazard Codes: Irritant Xi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36/37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
Hazard Note: Irritant
HazardClass: IRRITANT, KEEP COLD

3-Bromo-3,3-difluoropropene Specification

3-Bromo-3,3-difluoropropene , its cas register number is 420-90-6. It also can be called 3-Bromo-3,3-difluoro-1-propene ; 1,1-Difluoroallyl bromide ; Propene,3-bromo-3,3-difluoro- (6CI,7CI,8CI) .

Product Name

3-Bromo-3,3-difluoropropene

Synthetic route

3-Bromo-3,3-difluoropropene Chemical Properties

3-Bromo-3,3-difluoropropene Safety Profile

3-Bromo-3,3-difluoropropene Specification

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