3-methylanisole supplier | CasNO.100-84-5

Name
3-Methylanisole
EINECS 202-893-4
CAS No. 100-84-5
Article Data111
CAS DataBase
Density 0.941 g/cm³
Solubility Soluble in alcohol and insoluble in water.
Melting Point -47oC
Formula C₈H₁₀O
Boiling Point 172.2 °C at 760 mmHg
Molecular Weight 122.167
Flash Point 54.4 °C
Transport Information UN 1993 3/PG 3
Appearance colourless liquid
Safety 16-23-24/25
Risk Codes 10-22
Molecular Structure
Hazard Symbols Xn
Synonyms Anisole,m-methyl- (8CI);1-Methoxy-3-methylbenzene;3-Cresol methyl ether;3-Methoxytoluene;3-Methyl-1-methoxybenzene;Methyl m-tolylether;NSC 6255;m-Cresol methyl ether;m-Cresyl methyl ether;m-Methoxytoluene;m-Methylanisole;
PSA 9.23000
LogP 2.00360

Synthetic route

: 6971-51-3
3-methoxybenzyl alcohol

: 100-84-5
1-methoxy-3-methyl-benzene

Conditions

Conditions	Yield
With palladium dichloride In methanol at 40℃; for 18h; Inert atmosphere; Green chemistry; chemoselective reaction;	99%
With [IrCl(CO)(PPh3)2]; hydrazine hydrate; potassium hydroxide In methanol at 160℃; for 3h; Wolff-Kishner Reduction; Sealed tube;	86%
With [IrCl(CO)(PPh3)2]; hydrazine hydrate; potassium hydroxide In methanol at 160℃; for 3h; Sealed tube;	86%
With carbon monoxide; hydrogen; benzene unter Zusatz von Octacarbonyldikobalt und CoCO3 auf 190grad/238 at;
Multi-step reaction with 3 steps 1: 78 percent / sodium iodide; sodium hydride / tetrahydrofuran / 0 - 20 °C 2: sulfuryl chloride / CH2Cl2 / -78 °C 3: lithium; 4,4'-di-tert-butylbiphenyl / tetrahydrofuran / 1 h / 0 °C View Scheme

: 27060-75-9
4-bromo-3-methylanisole

: 100-84-5
1-methoxy-3-methyl-benzene

Conditions

Conditions	Yield
With potassium carbonate; butan-1-ol; palladium diacetate; triphenylphosphine at 100℃; for 14h;	98%

: 19924-43-7
3-methoxyphenylacetonitrile

: 100-84-5
1-methoxy-3-methyl-benzene

Conditions

Conditions	Yield
Stage #1: 3-methoxyphenylacetonitrile With 15-crown-5; sodium In tetrahydrofuran; hexane at 0℃; for 0.333333h; Birch Reduction; Inert atmosphere; Stage #2: With water In tetrahydrofuran; hexane at 0℃; for 1h; Birch Reduction; Inert atmosphere; chemoselective reaction;	98%
Stage #1: 3-methoxyphenylacetonitrile With dibenzo-18-crown-6; sodium In tetrahydrofuran; toluene at 0℃; for 0.333333h; Inert atmosphere; Stage #2: With propan-1-ol In tetrahydrofuran; toluene at 0℃; for 1h;	78%

: 591-31-1
3-methoxy-benzaldehyde

: 100-84-5
1-methoxy-3-methyl-benzene

Conditions

Conditions	Yield
Stage #1: 3-methoxy-benzaldehyde With iron(III) chloride In methanol at 20℃; for 0.05h; Stage #2: In methanol at 20℃; for 0.166667h; chemoselective reaction;	95%
With borohydride exchange resin; nickel diacetate In methanol for 3h; Ambient temperature;	93%
With triethylsilane; palladium dichloride In ethanol for 0.5h; Inert atmosphere;	86.0 %Chromat.
With triethylsilane; palladium dichloride In ethanol at 20℃; for 0.5h; Inert atmosphere;	86 %Chromat.

: 63452-69-7
1-iodo-4-methoxy-2-methylbenzene

: 100-84-5
1-methoxy-3-methyl-benzene

Conditions

Conditions	Yield
With potassium carbonate; butan-1-ol; palladium diacetate; triphenylphosphine at 100℃; for 1h;	93%

: 74-87-3
methylene chloride

: 108-39-4
3-methyl-phenol

: 100-84-5
1-methoxy-3-methyl-benzene

Conditions

Conditions	Yield
With benzyltrimethylammonium chloride; sodium hydroxide In water at 70℃; Concentration; Temperature; Autoclave;	92.2%

: 155496-74-5
1-Methoxy-3-methyl-2-(2-methyl-propane-2-sulfonyl)-benzene

: 100-84-5
1-methoxy-3-methyl-benzene

Conditions

Conditions	Yield
With bis(acetylacetonate)nickel(II); isopropylmagnesium chloride In tetrahydrofuran at 20℃; for 20h;	92%

: 77-78-1
dimethyl sulfate

Amberlite IRA-400 m-cresolate anion: Amberlite IRA-400 m-cresolate anion

: 100-84-5
1-methoxy-3-methyl-benzene

Conditions

Conditions	Yield
In methanol for 1.6h; Methylation;	92%

: 108-39-4
3-methyl-phenol

: 77-78-1
dimethyl sulfate

: 100-84-5
1-methoxy-3-methyl-benzene

Conditions

Conditions	Yield
With sodium hydroxide at 50℃; for 5h;	91.8%
With sodium hydroxide

: 67-56-1
methanol

: 591-24-2, 625-96-7
3-Methylcyclohexanone

: 100-84-5
1-methoxy-3-methyl-benzene

Conditions

Conditions	Yield
With ethene; 5%-palladium/activated carbon at 130℃; under 760.051 Torr;	88%

: 1527-89-5
3-methoxybenzonitrile

: 100-84-5
1-methoxy-3-methyl-benzene

Conditions

Conditions	Yield
With 20 % Pd(OH)2/C; hydrogen In methanol at 20℃; under 760.051 Torr; for 3h;	86%

: 108-39-4
3-methyl-phenol

: 74-88-4
methyl iodide

: 100-84-5
1-methoxy-3-methyl-benzene

Conditions

Conditions	Yield
With potassium carbonate In acetone at 72℃; for 24h; Inert atmosphere;	85%
With sodium hydroxide In N,N-dimethyl acetamide at 25℃; Rate constant;
With potassium hydroxide

: 598-99-2
Methyl trichloroacetate

: 108-39-4
3-methyl-phenol

: 100-84-5
1-methoxy-3-methyl-benzene

Conditions

Conditions	Yield
With 18-crown-6 ether; potassium carbonate at 150℃; for 2h;	85%

: 108-39-4
3-methyl-phenol

: 616-38-6
carbonic acid dimethyl ester

: 100-84-5
1-methoxy-3-methyl-benzene

Conditions

Conditions	Yield
With N,N'-dimethylimidazolium-2-carboxylate In acetonitrile at 160℃; for 1.33333h; Microwave irradiation; Green chemistry;	84%
With dimanganese decacarbonyl at 180℃; for 1h; Reagent/catalyst;	81%
With 1,8-diazabicyclo[5.4.0]undec-7-ene at 90℃; Inert atmosphere;

: 41977-20-2
(2R,3S)-2,3-dihydroxy-1-methylcyclohexa-4,6-diene

: 74-88-4
methyl iodide

A: 578-58-5
2-methylmethoxybenzene

B: (5S,6R)-dimethoxy-1-methylcyclohexa-1,3-diene

C: 100-84-5
1-methoxy-3-methyl-benzene

Conditions

Conditions	Yield
With potassium hydroxide In dimethyl sulfoxide at 0℃; for 1.5h;	A n/a B 80% C n/a

...Expand

: 1026136-94-6
2-tert-butylsulfinyl-3-methoxytoluene

: 100-84-5
1-methoxy-3-methyl-benzene

Conditions

Conditions	Yield
With nickel In ethanol for 8h; Reflux;	80%

: 824-98-6
m-methoxybenzyl chloride

A: 36707-27-4
1,2-bis(3-methoxyphenyl)ethane

B: 100-84-5
1-methoxy-3-methyl-benzene

Conditions

Conditions	Yield
With nickel In 1,2-dimethoxyethane for 6h; Ambient temperature;	A 69% B n/a

: 2398-37-0
3-methoxyphenyl bromide

: 917-54-4
methyllithium

: 100-84-5
1-methoxy-3-methyl-benzene

Conditions

Conditions	Yield
Stage #1: 3-methoxyphenyl bromide With bis(tri-t-butylphosphine)palladium(0); oxygen In toluene at 20℃; for 0.0166667h; Schlenk technique; Stage #2: methyllithium In toluene at 20℃; for 0.0333333h; Schlenk technique;	69%

: 110-62-3
pentanal

: 1798-09-0
m-methoxyphenylacetic acid

A: 1250895-32-9
1-(3-methoxyphenyl)hexan-2-ol

B: 100-84-5
1-methoxy-3-methyl-benzene

Conditions

Conditions	Yield
With (4s,6s)-2,4,5,6-tetra(9H-carbazol-9-yl)isophthalonitrile; caesium carbonate In N,N-dimethyl acetamide at 20℃; for 16h; Irradiation; Inert atmosphere;	A 63% B 20 %Chromat.

...Expand

: 67-56-1
methanol

: 108-39-4
3-methyl-phenol

A: 95-87-4
2,5-Dimethylphenol

B: 526-75-0
2,3-Dimethylphenol

C: 2416-94-6
2,3,6-trimethylphenol

D: 100-84-5
1-methoxy-3-methyl-benzene

Conditions

Conditions	Yield
silica gel at 350℃; under 61504.9 Torr; Product distribution; Further Variations:; Catalysts; Pressures; Temperatures;	A 46% B 9% C 38% D n/a

...Expand

: 863727-67-7
2-methoxy-6-methylphenyl trifluoromethanesulfonate

: 100-84-5
1-methoxy-3-methyl-benzene

Conditions

Conditions	Yield
With formic acid; tributyl-amine; 1,3-bis-(diphenylphosphino)propane; bis-triphenylphosphine-palladium(II) chloride In N,N-dimethyl-formamide at 80℃; for 8h;	46%

: 194018-68-3
vanillin triflate

A: 6971-51-3
3-methoxybenzyl alcohol

B: 100-84-5
1-methoxy-3-methyl-benzene

Conditions

Conditions	Yield
With palladium 10% on activated carbon; hydrogen In ethyl acetate at 20℃; under 760.051 Torr; for 40h;	A 30% B 42%

: 67-56-1
methanol

: 108-95-2
phenol

A: 104-93-8
4-Methylanisole

B: 578-58-5
2-methylmethoxybenzene

C: 1004-66-6
2-methoxy-1,3-dimethylbenzene

D: 6738-23-4
2,4-dimethylanisole

E: 100-66-3
methoxybenzene

F: 100-84-5
1-methoxy-3-methyl-benzene

Conditions

Conditions	Yield
APTi-II-770 at 349.9℃; Product distribution; alkylation; other catalysts, other temperatures; also cresols, further products;	A n/a B 1.8% C n/a D n/a E 19% F n/a

...Expand

: 25649-41-6
4,4',4''-((1,3,5-triazine-2,4,6-triyl)tris(oxy))tris(3-methoxybenzaldehyde)

: 100-84-5
1-methoxy-3-methyl-benzene

Conditions

Conditions	Yield
With palladium 10% on activated carbon; hydrogen In ethyl acetate at 20℃; for 24h;	14%

: 766-85-8
3-methoxy-1-iodobenzene

: 3385-78-2
trimethyl indium

: 100-84-5
1-methoxy-3-methyl-benzene

Conditions

Conditions	Yield
With water; tris-(dibenzylideneacetone)dipalladium(0); trifuran-2-yl-phosphane In tetrahydrofuran Heating;	3%

: 2398-37-0
3-methoxyphenyl bromide

: 100-84-5
1-methoxy-3-methyl-benzene

Conditions

Conditions	Yield
With diethyl ether; magnesium anschliessend Behandeln mit Dimethylsulfat, zuletzt auf dem Dampfbad;

: 60-29-7
diethyl ether

: 38197-43-2
2-bromo-3-methylanisole

: 3585-33-9
lithium dimethylamide

A: 2-bromo-3,N,N-trimethyl-aniline

B: 100-84-5
1-methoxy-3-methyl-benzene

...Expand

: 5456-94-0
2,4-dibromo-5-methylanisole

A: 27060-75-9
4-bromo-3-methylanisole

B: 100-84-5
1-methoxy-3-methyl-benzene

Conditions

Conditions	Yield
With diethyl ether; magnesium anschliessende Hydrolyse;

: 67-56-1
methanol

: 108-39-4
3-methyl-phenol

: 100-84-5
1-methoxy-3-methyl-benzene

Conditions

Conditions	Yield
at 400 - 420℃; durch Ueberleiten ueber ThO2;

: 100-84-5
1-methoxy-3-methyl-benzene

: 27060-75-9
4-bromo-3-methylanisole

Conditions

Conditions	Yield
With hydrogenchloride; N-Bromosuccinimide; water In acetone at 20℃; for 0.0833333h; Inert atmosphere;	100%
With 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione; methyl 2-n-pentyl-1H-indole-3-carboxylate In n-heptane at 23℃; for 16h; Darkness; Green chemistry; regioselective reaction;	99%
With N-Bromosuccinimide; 2,4,6-trimethylaniline In dichloromethane at -40℃; for 2h; Inert atmosphere; regioselective reaction;	98%

: 100-84-5
1-methoxy-3-methyl-benzene

: 63452-69-7
1-iodo-4-methoxy-2-methylbenzene

Conditions

Conditions	Yield
With iodine; n-butyltriphenylphosphonium peroxodisulfate In acetonitrile for 0.5h; Heating;	100%
With N,N,N-trimethylbenzenemethanaminium dichloroiodate; zinc(II) chloride In acetic acid for 0.5h; Ambient temperature;	94%
With N-iodo-succinimide; 2,4,6-trifluoroaniline In dichloromethane at 20℃; for 24h; Inert atmosphere; regioselective reaction;	94%

: 100-84-5
1-methoxy-3-methyl-benzene

: C8H9KO

Conditions

Conditions	Yield
Stage #1: 1-methoxy-3-methyl-benzene With potassium tert-butylate at -35℃; for 0.333333h; Stage #2: With n-butyllithium In hexane at -35 - 20℃; for 12h;	100%

: 100-84-5
1-methoxy-3-methyl-benzene

: 19614-12-1
2-bromo-5-methoxybenzyl bromide

Conditions

Conditions	Yield
With N-Bromosuccinimide In dichloromethane for 4h; Heating; IR lamp;	99%
With N-Bromosuccinimide In dichloromethane for 4h; Bromination; Heating; irradiation;	88%
With N-Bromosuccinimide Photolysis;	88%

: 13274-43-6
4-methyl-1,2,4-triazoline-3,5-dione

: 100-84-5
1-methoxy-3-methyl-benzene

: 1268396-59-3
1-(4-methoxy-2-methylbenzene)-4-methyl-1,2,4-triazoline-3,5-dione

Conditions

Conditions	Yield
With trifluoroacetic acid In chloroform at 62℃; for 0.166667h; regioselective reaction;	99%

: 696-63-9
4-Methoxybenzenethiol

: 100-84-5
1-methoxy-3-methyl-benzene

: (4-methoxy-2-methylphenyl)(4-methoxyphenyl)sulfane

Conditions

Conditions	Yield
With tetrabutylammonium acetate for 4.5h; Electrolysis; Inert atmosphere; Sealed tube; regioselective reaction;	99%

: 128-08-5
N-Bromosuccinimide

: 100-84-5
1-methoxy-3-methyl-benzene

: 27060-75-9
4-bromo-3-methylanisole

Conditions

Conditions	Yield
In dichloromethane at 20℃;	98%

: 100-84-5
1-methoxy-3-methyl-benzene

A: 1193-18-6
3-methylcyclohexen-2-one

B: 591-24-2, 625-96-7
3-Methylcyclohexanone

Conditions

Conditions	Yield
With N,N,N,N,N,N-hexamethylphosphoric triamide; lithium In tetrahydrofuran; ethanol at -30℃; for 2h;	A 97% B 3%

: 100-84-5
1-methoxy-3-methyl-benzene

: 13334-71-9
1-chloro-4-methoxy-2-methylbenzene

Conditions

Conditions	Yield
With N-chloro-succinimide; 2,4,6-trimethylaniline In dichloromethane at 20℃; Inert atmosphere; regioselective reaction;	96%
With aluminum oxide; sodium chlorite; (salen)Mn(III) In dichloromethane at 20℃; for 0.5h;	87%
With Oxone; potassium chloride In water; acetonitrile at 20℃;	76%

: 100-84-5
1-methoxy-3-methyl-benzene

: 117934-78-8
2,4-diiodo-5-methyl-methoxybenzene

Conditions

Conditions	Yield
With N,N,N-trimethylbenzenemethanaminium dichloroiodate; zinc(II) chloride In acetic acid for 24h; Ambient temperature;	96%
With iodine; mercury(II) oxide In dichloromethane for 20h; Ambient temperature;	80%
With sulfuric acid; iodine; periodic acid In water; acetic acid

: 100-84-5
1-methoxy-3-methyl-benzene

: 82101-67-5
1-deuteriomethyl-3-methoxybenzene

Conditions

Conditions	Yield
Stage #1: 1-methoxy-3-methyl-benzene With 2,2,6,6-tetramethyl-piperidine; n-butyllithium; potassium tert-butylate In tetrahydrofuran; hexane at -78℃; Inert atmosphere; Stage #2: With d(4)-methanol In tetrahydrofuran; hexane Inert atmosphere; regioselective reaction;	96%

: 100-84-5
1-methoxy-3-methyl-benzene

: 24318-46-5
3-methoxybenzyl 3-methoxybenzoate

Conditions

Conditions	Yield
With tert.-butylhydroperoxide; tetra-(n-butyl)ammonium iodide In water at 80℃; for 6h;	96%

: 100-84-5
1-methoxy-3-methyl-benzene

: 108-39-4
3-methyl-phenol

Conditions

Conditions	Yield
With N,N,N,N,N,N-hexamethylphosphoric triamide; sodium hydride; N-methylaniline In diethyl ether; xylene at 120℃; for 6.5h;	95%
With trimethylsilyl iodide at 105 - 114℃; for 0.25h; Microwave irradiation; Inert atmosphere;	92%
With 1,3-dimethyl-2-imidazolidinone; sodium hexamethyldisilazane In tetrahydrofuran at 185℃; for 12h; further reagent: LDA;	87%

: 2712-78-9
bis-[(trifluoroacetoxy)iodo]benzene

: 100-84-5
1-methoxy-3-methyl-benzene

: (2-methyl-4-methoxyphenyl)phenyliodonium trifluoroacetate

Conditions

Conditions	Yield
In methanol; water at 20℃; for 2h;	95%
With trifluoroacetic acid

: [(2,6-bis(diphenylphosphinomethyl)pyridine)Pt(C2H4)](SbF6)2

: 100-84-5
1-methoxy-3-methyl-benzene

: 952514-33-9
[(2,6-bis(diphenylphosphinomethyl)pyridine)Pt(C2H4C6H3(OMe)Me)]SbF6

: 952514-35-1
[(2,6-bis(diphenylphosphinomethyl)pyridine)Pt(C2H4C6H3(OMe)Me)]SbF6

Conditions

Conditions	Yield
In dichloromethane; water aryl compd. (1.5 equiv.) and H2O were added to soln. of Pt complex in CH2Cl2; mixt. was stirred for 2 h; dried (Na2SO4); filtered; concd. (vac.); Et2O added dropwise; filtered; dried (vac.); elem. anal.;	A 95% B n/a

...Expand

: 2-((trifluoromethyl)thio)benzo[d]isothiazol-3(2H)-one 1,1-dioxide

: 100-84-5
1-methoxy-3-methyl-benzene

: 4-methoxy-2-methyl-1-[(trifluoromethyl)thio]benzene

Conditions

Conditions	Yield
With iron(III) chloride; silver hexafluoroantimonate In 1,2-dichloro-ethane at 100℃; for 16h; Inert atmosphere; Sealed tube;	95%

: 507-20-0
tertiary butyl chloride

: 100-84-5
1-methoxy-3-methyl-benzene

: 88-40-4
2-tert-butyl-5-methylanisole

Conditions

Conditions	Yield
rhenium(I) pentacarbonyl bromide In 1,2-dichloro-ethane at 84℃; for 5h; Product distribution;	93%
Stage #1: 1-methoxy-3-methyl-benzene With aluminum (III) chloride In dichloromethane at 0 - 5℃; for 1h; Stage #2: tertiary butyl chloride In dichloromethane at 0 - 5℃; for 5h; Temperature;	87.46%
With phosphoric acid at 55 - 60℃;
With aluminium trichloride
With aluminium trichloride

: 100-84-5
1-methoxy-3-methyl-benzene

: 1527-89-5
3-methoxybenzonitrile

Conditions

Conditions	Yield
With [2,2]bipyridinyl; ammonia; dihydrogen peroxide; oxygen In N,N-dimethyl-formamide at 80℃; under 1500.15 - 3000.3 Torr; for 6h; Autoclave;	93%
With tert.-butylnitrite; N-hydroxyphthalimide; palladium diacetate In acetonitrile at 70℃; for 24h; Inert atmosphere; Sealed tube;	81%
With air; ammonia; vanadium-titanium oxide at 383.9℃; for 0.000333333h;	16.1

: 557-21-1
dicyanozinc

: 100-84-5
1-methoxy-3-methyl-benzene

: 52289-54-0
4-methoxysalicylaldehyde

Conditions

Conditions	Yield
Stage #1: dicyanozinc; 1-methoxy-3-methyl-benzene With hydrogenchloride In 1,1,2,2-tetrachloroethane at 17℃; Stage #2: With aluminium trichloride In 1,1,2,2-tetrachloroethane at 55℃; for 3h;	93%

: 140-10-3
(E)-3-phenylacrylic acid

: 100-84-5
1-methoxy-3-methyl-benzene

A: 131866-19-8
3-(4-hydroxy-2-methyl-phenyl)-3-phenyl-propionic acid

B: 109089-78-3
3-(4-methoxy-2-methyl-phenyl)-3-phenyl-propionic acid

Conditions

Conditions	Yield
With toluene-4-sulfonic acid at 125℃; for 3h;	A 5% B 93%

...Expand

: 69180-49-0
1-diacetoxy-2-methoxyphenyl-λ3-iodane

: 76-05-1
trifluoroacetic acid

: 100-84-5
1-methoxy-3-methyl-benzene

: 4-methoxy-2-methylphenyl(2-methoxyphenyl)iodonium trifluoroacetate

Conditions

Conditions	Yield
In dichloromethane at -30 - 20℃;	93%

...Expand

: 100-84-5
1-methoxy-3-methyl-benzene

: 57356-79-3
4-hydroxy-3-methyl-cyclohex-2-en-1-one

Conditions

Conditions	Yield
Stage #1: 1-methoxy-3-methyl-benzene With ammonia; lithium; tert-butyl alcohol In diethyl ether at -78℃; Birch reduction; Inert atmosphere; Stage #2: With oxalic acid In methanol; water at 20℃; for 1h; Stage #3: With 3-chloro-benzenecarboperoxoic acid In dichloromethane at 20℃; for 3h; Inert atmosphere;	93%

: 4294-57-9
para-methylphenylmagnesium bromide

: 100-84-5
1-methoxy-3-methyl-benzene

: 7383-90-6
3,4'-dimethylbiphenyl

Conditions

Conditions	Yield
With bis(1,5-cyclooctadiene)nickel (0); C23H28N4 In tetrahydrofuran; m-xylene at 60℃; for 4h; Kumada Cross-Coupling; Inert atmosphere; Sealed tube;	93%
With (IPr)Ni(π-allyl)Cl In tetrahydrofuran at 60℃; for 12h; Kumada Cross-Coupling; Inert atmosphere;	81%

: 100-84-5
1-methoxy-3-methyl-benzene

: 13697-84-2
1-methoxy-5-methyl-cyclohexa-1,4-diene

Conditions

Conditions	Yield
With lithium In ethanol; ammonia at -78℃; for 0.5h;	92%
With ammonia; sodium In diethyl ether at -78 - -35℃; for 2h;	82%
With ammonia; sodium In diethyl ether; tert-butyl alcohol at -78 - -35℃; for 2h;	82%

3-methylanisole Chemical Properties

IUPAC Name: 1-methoxy-3-methylbenzene
The MF of 3-methylanisole(100-84-5): C₈H₁₀O
The MW of 3-methylanisole(100-84-5): 122.16
EINECS: 202-893-4
bp: 175-176 °C(lit.)
density: 0.969 g/mL at 25 °C(lit.)
refractive index: n20/D 1.513(lit.)
Fp: 130 °F
storage temp.: Flammables area
Appearance: Clear very slight yellow liquid.
Solubility in water: Insoluble
Stability: Stable. Flammable. Incompatible with strong oxidizing agents.
Categories: Aromatic Hydrocarbons (substituted) & Derivatives;Aromatic Ethers;AnisoleSeries;Anisoles, Alkyloxy Compounds & Phenylacetates;Ethers;Organic Building Blocks;Oxygen Compounds
Synonyms: 1-METHOXY-3-METHYLBENZENE;AMBROL;3-METHOXYTOLUENE;3-METHYLANISOLE;METHYL M-TOLYL ETHER;METHYL-M-CRESOL;M-CRESOL METHYL ETHER;M-CRESYL METHYL ETHER
The Structure of 3-methylanisole(100-84-5):

3-methylanisole Uses

3-methylanisole(100-84-5) is mainly used for synthetic dyes and pharmaceutical intermediates.

3-methylanisole Toxicity Data With Reference

1. mouse LD intraperitoneal > 500mg/kg (500mg/kg)
"Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. Vol. 6, Pg. 214, 1954.

3-methylanisole Safety Profile

Hazard Codes:

Xn
Risk Statements: 10-22
10: Flammable
22: Harmful if swallowed
Safety Statements: 16-23-24/25
16: Keep away from sources of ignition - No smoking
23: Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer)
24/25: Avoid contact with skin and eyes
RIDADR: UN 1993 3/PG 3
WGK Germany: 3
RTECS: BZ8778000
HazardClass: 3
PackingGroup: III

3-methylanisole Specification

1. First Aid Measures
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
2. Handling and Storage
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.
Handling:
Wash thoroughly after handling. Use only in a well ventilated area. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.

Product Name

3-Methylanisole

Synthetic route

3-methylanisole Chemical Properties

3-methylanisole Uses

3-methylanisole Toxicity Data With Reference

3-methylanisole Safety Profile

3-methylanisole Specification

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